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acetaminophen and Hyperglycemia

acetaminophen has been researched along with Hyperglycemia in 15 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"To test the possibility that aging-related hyperglycemia can be prevented by pharmacological manipulation of MAPK hyperactivation, aged (27-month old) Fischer 344/NNiaHSD x Brown Norway/BiNia F1 (F344BN) rats were administered acetaminophen (30 mg/kg body weight/day) for 6 months in drinking water."7.75Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2. ( Blough, ER; Desai, DH; Gutta, AK; Kakarla, SK; Katta, A; Paturi, S; Rice, KM; Walker, EM; Wu, M, 2009)
"We examined the contributions of insulin secretion, glucagon suppression, splanchnic and peripheral glucose metabolism, and delayed gastric emptying to the attenuation of postprandial hyperglycemia during intravenous exenatide administration."7.74Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. ( Cersosimo, E; Cervera, A; DeFronzo, RA; Fernandez, M; Musi, N; Sriwijitkamol, A; Triplitt, C; Wajcberg, E; Zuo, P, 2008)
" Although her consciousness and hemodynamic status gradually improved after treatment with N-acetylcysteine and other supportive measures, she was found to have pancytopenia, pancreatitis and hepatorenal failure during the hospitalization and eventually died 18 d post-admission."7.71Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning. ( Deng, JF; Lin, TJ; Yang, CC, 2001)
" A comparison of the dose-response curves for hepatic glycogen depletion and glutathione depletion showed that acetaminophen (50-500 mg/kg at 2."5.27Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice. ( Cameron, AM; Hinson, JA; Mays, JB, 1983)
"To test the possibility that aging-related hyperglycemia can be prevented by pharmacological manipulation of MAPK hyperactivation, aged (27-month old) Fischer 344/NNiaHSD x Brown Norway/BiNia F1 (F344BN) rats were administered acetaminophen (30 mg/kg body weight/day) for 6 months in drinking water."3.75Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2. ( Blough, ER; Desai, DH; Gutta, AK; Kakarla, SK; Katta, A; Paturi, S; Rice, KM; Walker, EM; Wu, M, 2009)
"We examined the contributions of insulin secretion, glucagon suppression, splanchnic and peripheral glucose metabolism, and delayed gastric emptying to the attenuation of postprandial hyperglycemia during intravenous exenatide administration."3.74Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. ( Cersosimo, E; Cervera, A; DeFronzo, RA; Fernandez, M; Musi, N; Sriwijitkamol, A; Triplitt, C; Wajcberg, E; Zuo, P, 2008)
" Although her consciousness and hemodynamic status gradually improved after treatment with N-acetylcysteine and other supportive measures, she was found to have pancytopenia, pancreatitis and hepatorenal failure during the hospitalization and eventually died 18 d post-admission."3.71Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning. ( Deng, JF; Lin, TJ; Yang, CC, 2001)
"Twenty-five patients (45-73 years) with type 2 diabetes [glycated haemoglobin (HbA1c) 6."2.73Pre-operative carbohydrate loading may be used in type 2 diabetes patients. ( Gustafsson, UO; Hagström-Toft, E; Hellström, PM; Ljungqvist, O; Nygren, J; Soop, M; Thorell, A, 2008)
"Hyperglycemia was induced by the administration of streptozotocin."1.72Investigation of Intestinal Absorption and Excretion of Paracetamol in Streptozotocin-Induced Hyperglycemia. ( Almási, A; Kovács, S; Kulcsár, G; Mészáros, P; Páskuj, M, 2022)
"Five subjects with poorly controlled IDDM and six age-weight-matched control subjects were clamped at a mean plasma glucose concentration of approximately 9 mM and mean plasma insulin concentrations approximately 400 pM for 5 h."1.2913C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. ( Cline, GW; Katz, LD; Magnusson, I; Rothman, DL; Shulman, GI, 1994)
"When post-ischemic seizures ensued in hyperglycemic subjects, temperature was 39."1.29Preischemic hyperglycemia leads to delayed postischemic hyperthermia. ( Lundgren, J; Siesjö, BK; Smith, ML; Uchino, H, 1994)
" A comparison of the dose-response curves for hepatic glycogen depletion and glutathione depletion showed that acetaminophen (50-500 mg/kg at 2."1.27Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice. ( Cameron, AM; Hinson, JA; Mays, JB, 1983)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's5 (33.33)18.2507
2000's5 (33.33)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Mészáros, P1
Kovács, S1
Kulcsár, G1
Páskuj, M1
Almási, A1
Drury, P1
Levi, C1
McInnes, E1
Hardy, J1
Ward, J1
Grimshaw, JM1
D' Este, C1
Dale, S1
McElduff, P1
Cheung, NW1
Quinn, C1
Griffiths, R1
Evans, M1
Cadilhac, D1
Middleton, S1
Montagnana, M1
Caputo, M1
Giavarina, D1
Lippi, G1
Wu, M1
Desai, DH1
Kakarla, SK1
Katta, A1
Paturi, S1
Gutta, AK1
Rice, KM1
Walker, EM1
Blough, ER1
Gustafsson, UO1
Nygren, J1
Thorell, A1
Soop, M1
Hellström, PM1
Ljungqvist, O1
Hagström-Toft, E1
Cervera, A1
Wajcberg, E1
Sriwijitkamol, A1
Fernandez, M1
Zuo, P1
Triplitt, C1
Musi, N1
DeFronzo, RA1
Cersosimo, E1
Farah, DA1
Boag, D1
Moran, F1
McIntosh, S1
Hinson, JA1
Mays, JB1
Cameron, AM1
Lawrence, IG1
Lear, J1
Burden, AC1
Maddocks, E1
Smith, JF1
Cline, GW1
Rothman, DL1
Magnusson, I1
Katz, LD1
Shulman, GI1
Uchino, H1
Lundgren, J1
Smith, ML1
Siesjö, BK1
Dunn, RJ1
Yang, CC1
Deng, JF1
Lin, TJ1
Copland, AM1
Mather, J1
Ness, A1
Fulton, JD1
Thomson, JS1
Prescott, LF1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Preoperative Oral Carbohydrates on the Glycemic Variability of Diabetic Patients[NCT04013594]50 participants (Actual)Interventional2019-08-20Completed
Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study[NCT03220997]200 participants (Anticipated)Interventional2017-08-31Not yet recruiting
The Effect of Carbohydrate Loading on Gastric Residual Volume and Hunger Score: A Single Blind, Randomised Controlled Trial Study[NCT03948594]78 participants (Anticipated)Interventional2019-05-31Not yet recruiting
Impact of Preoperative Oral Carbohydrate on Recovery in Diabetic Patients After Gastrointestinal Surgery: a Pilot Randomized Controlled Trial[NCT03204344]65 participants (Actual)Interventional2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetaminophen and Hyperglycemia

ArticleYear
Overview on self-monitoring of blood glucose.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 402, Issue:1-2

    Topics: Acetaminophen; Blood Glucose Self-Monitoring; Calibration; Diabetes Mellitus; Hematocrit; Humans; Hy

2009

Trials

1 trial available for acetaminophen and Hyperglycemia

ArticleYear
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008
Pre-operative carbohydrate loading may be used in type 2 diabetes patients.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Beverages; Blood Glucose; Diabetes Mellitus, Type 2;

2008

Other Studies

13 other studies available for acetaminophen and Hyperglycemia

ArticleYear
Investigation of Intestinal Absorption and Excretion of Paracetamol in Streptozotocin-Induced Hyperglycemia.
    International journal of molecular sciences, 2022, Oct-07, Volume: 23, Issue:19

    Topics: Acetaminophen; Acetylcysteine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Glucuronide

2022
Management of fever, hyperglycemia, and swallowing dysfunction following hospital admission for acute stroke in New South Wales, Australia.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9, Issue:1

    Topics: Acetaminophen; Aged; Aged, 80 and over; Antipyretics; Cohort Studies; Deglutition Disorders; Female;

2014
Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2.
    Diabetes/metabolism research and reviews, 2009, Volume: 25, Issue:3

    Topics: Acetaminophen; Aging; Animals; Blood Glucose; Enzyme Activation; Glucose Transporter Type 4; Hypergl

2009
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 294, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Glucose; Diabetes Mellitus, Type 2; Exenatide;

2008
Paracetamol interference with blood glucose analysis: a potentially fatal phenomenon.
    British medical journal (Clinical research ed.), 1982, Jul-17, Volume: 285, Issue:6336

    Topics: Acetaminophen; Blood Glucose; Female; Humans; Hyperglycemia; Middle Aged

1982
Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice.
    Biochemical pharmacology, 1983, Jul-01, Volume: 32, Issue:13

    Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Hypergl

1983
Hyperglycaemia induced by paracetamol.
    Postgraduate medical journal, 1995, Volume: 71, Issue:841

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Humans; Hyperglycemia; Male; Time Factor

1995
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:6

    Topics: Acetaminophen; Adult; Carbon Isotopes; Citric Acid Cycle; Diabetes Mellitus, Type 1; Female; Glucose

1994
Preischemic hyperglycemia leads to delayed postischemic hyperthermia.
    Stroke, 1994, Volume: 25, Issue:9

    Topics: Acetaminophen; Animals; Body Temperature Regulation; Brain Ischemia; Fever; Glucose; Hypercapnia; Hy

1994
Massive sulfasalazine and paracetamol ingestion causing acidosis, hyperglycemia, coagulopathy, and methemoglobinemia.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Acute Disease; Adult; Anti-Inflammatory Agents; Blo

1998
Pancytopenia, hyperglycemia, shock, coma, rhabdomyolysis, and pancreatitis associated with acetaminophen poisoning.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Coma; Diagnosis, Diff

2001
Apparent hyperglycaemia in paracetamol overdose.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1992, Volume: 42, Issue:359

    Topics: Acetaminophen; Adult; Blood Glucose; Drug Overdose; False Positive Reactions; Humans; Hyperglycemia;

1992
Liver damage and impaired glucose tolerance after paracetamol overdosage.
    British medical journal, 1966, Aug-27, Volume: 2, Issue:5512

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Glucose Tolerance Test; Humans; Hyperglycemia

1966