Page last updated: 2024-10-31

metyrapone and Hyperglycemia

metyrapone has been researched along with Hyperglycemia in 6 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."5.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)
"Acute hyperglycemia was induced by IP injection of dextrose 30 minutes before ischemia."1.33Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation. ( Bargalló, N; Chamorro, A; Falcón, C; Martín, A; Planas, AM; Rojas, S, 2006)
"In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models."1.31Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martín, A1
Rojas, S1
Chamorro, A1
Falcón, C1
Bargalló, N1
Planas, AM1
Schurr, A1
Payne, RS1
Miller, JJ1
Tseng, MT1
Atiea, JA1
Aslan, SM1
Owens, DR1
Luzio, S1
Steel, K1
Baerg, RD1
Adams, DO1
Zicha, L1
Bergner, D1
Christmann, A1
Hardisty, MW1

Other Studies

6 other studies available for metyrapone and Hyperglycemia

ArticleYear
Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.
    Stroke, 2006, Volume: 37, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Disease Progression; Glycosylation; Hyperglycemia

2006
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
    Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticostero

2001
Early morning hyperglycaemia "dawn phenomenon" in non-insulin dependent diabetes mellitus (NIDDM): effects of cortisol suppression by metyrapone.
    Diabetes research (Edinburgh, Scotland), 1990, Volume: 14, Issue:4

    Topics: Aged; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 2; Epinephrine; Female; Gl

1990
Cushing's syndrome in association with a carcinoid tumor of the lung.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:9

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoid Tumor; Cushing Sy

1967
[Glucocorticoids and glucose metabolism. 2. Studies on the influence of metopirone on glucose tolerance with and without additional application of adrenocorticotropic hormone and prenisolone].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Hu

1966
Quantitative and experimental studies on the interrenal tissues of the upstream migrant stage of the river lamprey, Lampetra fluviatilis L.
    General and comparative endocrinology, 1972, Volume: 18, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cell Count; Cell Nucleus; Fishes; Hyperglycemi

1972