| Assay ID | Title | Year | Journal | Article |
|---|
| AID36997 | Inhibitory activity against alpha-fucosidase from bovine epididymis at concentration 1 mM | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID40150 | Inhibitory activity against beta-galactosidase from bovine liver | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID731623 | Induction of alpha galactosidase A R301Q mutant activity in lymphoblasts derived from Fabry disease patient at 100 uM after 4 days relative to control | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Pharmacological chaperones as therapeutics for lysosomal storage diseases. |
| AID37281 | Inhibitory activity against alpha-glucosidase from rat intestinal maltase at concentration 1 mM | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID37119 | Inhibitory activity against alpha-galactosidase from coffee bean. | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID37128 | Inhibitory activity against alpha-galactosidase from rat epididymis. | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID778972 | Inhibition of rat intestinal alpha-glucosidase using sucrose as substrate assessed as glucose formation incubated for 10 mins prior to substrate addition measured after 30 mins by glucose oxidase method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID37395 | Inhibitory activity measured against alpha-glucosidase of rat liver ER glucosidase II by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID778969 | Hypoglycemic effect in sucrose-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 120 mins by glucose oxidase method (Rvb = 137.8 +/- 14.5 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID342793 | Inhibition of rat intestinal brush border membrane maltase | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID342799 | Inhibition of human lysosomal alpha-glucosidase | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID37396 | Inhibitory activity measured against alpha-glucosidase of rat liver lysosomal by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID342802 | Inhibition of human lysosomal beta-glucosidase at 1000 uM | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID342805 | Inhibition of rabbit muscle amylo-1,6-glucosidase | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID342797 | Inhibition of rat intestinal brush border membrane sucrase | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID73345 | Inhibitory activity measured against beta-galactosidase of bovine liver by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID778970 | Hypoglycemic effect in sucrose-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 60 mins by glucose oxidase method (Rvb = 183.3 +/- 29.1 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID37129 | Inhibitory activity against alpha-galactosidase from rat epididymis at concentration 1 mM | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID37289 | Inhibitory activity measured against alpha-glucosidase of rat intestinal isomaltase by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID73342 | Inhibitory activity measured against alpha-galactosidase of coffee bean by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID37290 | Inhibitory activity measured against alpha-glucosidase of rat intestinal maltase by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID210964 | Inhibitory activity measured against trehalase of porcine kidney by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID40156 | Inhibitory activity against beta-galactosidase from bovine liver at concentration 1 mM | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID37260 | Inhibitory activity measured against alpha-glucosidase of rice by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID342795 | Inhibition of rat intestinal brush border membrane isomaltase | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID37291 | Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase method | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID778968 | Hypoglycemic effect in sucrose-challenged ICR mouse assessed as glucose AUC at 10 mg/kg, po by glucose oxidase method (Rvb = 323.2 +/- 37.2 mg.hr/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID342811 | Inhibition of maltase in human Caco-2 cell model system after 2 hrs | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID73348 | Inhibitory activity measured against beta-galactosidase of rat intestinal lactase by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID37120 | Inhibitory activity against alpha-galactosidase from coffee bean at concentration 1 mM | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID778966 | Hypoglycemic effect in starch-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 60 mins by glucose oxidase method (Rvb = 243.0 +/- 29.0 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID778964 | Hypoglycemic effect in starch-challenged ICR mouse assessed as glucose AUC at 10 mg/kg, po by glucose oxidase method (Rvb = 430.1 +/- 44.7 mg.hr/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID400363 | Antihyperglycemic effect in STZ-diabetic ddY mouse assessed as reduction in blood glucose level at 150 umol/kg, ip by glucose oxidase method | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3
| Antihyperglycemic effects of N-containing sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castanospermum australe in streptozotocin-diabetic mice. |
| AID37280 | Inhibitory activity against alpha-glucosidase from rat intestinal maltase | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21
| Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
| AID778971 | Hypoglycemic effect in sucrose-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 30 mins by glucose oxidase method (Rvb = 187.4 +/- 21.6 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID778965 | Hypoglycemic effect in starch-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 120 mins by glucose oxidase method (Rvb = 174.2 +/- 22.9 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID342804 | Inhibition of rabbit glycogen phosphorylase B at 400 uM | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
| AID36824 | Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID36965 | Inhibitory activity measured against alpha-L-fucosidase of rat epididymis by colorimetric assay using the D-glucose oxidase-peroxidase method at 1000 uM | 1998 | Journal of medicinal chemistry, Jul-02, Volume: 41, Issue:14
| Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. |
| AID778967 | Hypoglycemic effect in starch-challenged ICR mouse assessed as blood glucose level at 10 mg/kg, po after 30 mins by glucose oxidase method (Rvb = 278.9 +/- 33.5 mg/dL) | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21
| α-Glucosidase-inhibitory iminosugars from the leaves of Suregada glomerulata. |
| AID1797728 | In Vitro Enzyme Inhibition from Article 10.1016/j.bmc.2006.08.003: \\Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.\\ | 2006 | Bioorganic & medicinal chemistry, Dec-01, Volume: 14, Issue:23
| Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |