Page last updated: 2024-08-17

nadp and Hyperglycemia

nadp has been researched along with Hyperglycemia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's5 (15.15)18.2507
2000's4 (12.12)29.6817
2010's11 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Griesel, BA; Gurley, JM; Jackson, RM; Olson, AL; Szweda, LI1
Flyvbjerg, A; Greenbaum, AL; Grønbaek, H; Kunjara, S; McLean, P; Sochor, M1
Berlovskaya, E; Cherkasova, O; Fadeev, V; Priezzhev, A; Shirshin, E; Tikhonova, T1
Agarkov, AA; Popova, TN; Voronkova, YG; Zinovkin, RA1
Chen, X; Cheung, WW; Huang, R; Ji, X; Lan, T; Li, C; Li, N; Liu, B; Ou, Y; Wang, L; Yang, G; Yang, Z; Yuan, K1
Cao, H; Huang, Q; Ji, L; Jing, Z; Li, F; Li, J; Liu, F; Xing, J; Yin, C; Zhao, Y1
Floyd, BC; George, S; Gupte, RS; Gupte, SA; Kozicky, M; Neito, V; Recchia, F; Serpillon, S; Stanley, W; Wolin, MS1
Choi, MS; Ha, SO; Huh, TL; Jeon, SM; Kim, K; Koh, HJ; Kwon, OS; Lee, SH1
Druhan, LJ; Ilangovan, G; Presley, T; Vedam, K1
Bhadhuri, G; Bhattacharya, B; Choudhuri, S; Chowdhury, IH; Dutta, D; Mandal, LK; Mukherjee, A; Paine, SK; Saha, A; Sen, A1
Johnston, KC; Southerland, AM1
Duarte, FV; Gomes, AP; Palmeira, CM; Rolo, AP; Teodoro, JS; Varela, AT1
Baiza-Gutman, LA; Cruz, M; Díaz-Flores, M; Durán-Reyes, G; Galván, RE; Gutiérrez, M; Ibáñez-Hernández, MA; Medina-Navarro, R; Ortega-Camarillo, C; Pascoe-Lira, D; Vilar-Rojas, C1
Chen, YW; Hébert, MJ; Ingelfinger, JR; Liu, F; Tran, S; Zhang, SL; Zhu, Y1
Hothersall, JS; Muirhead, RP1
Nourooz-Zadeh, J; Ou, P; Tritschler, HJ; Wolff, S1
Ido, Y; Williamson, JR1
Duckworth, WC1
Blackmore, PF; Clark, MG; Irving, MG; Regtop, HL; Rienits, KG; Taylor, BL; Williams, JF1
Gabbay, KH1
Hothersall, JS; Jones, RH; Muirhead, RP; Taylaur, CE1
Hotta, N; Sakamoto, N1
Jain, SK1
Das, B; Srivastava, SK1
Agren, A; Berne, C; Brolin, SE1
Polk, HC; Robertson, HD1
Christians, J; Hasselblatt, A; Panten, U; Poser, W; von Kriegstein, E1
Ellerman, JE; Fertel, R; Kotler-Brajtburg, J; krzanowski, J; Matschinsky, FM1
Gabbay, KH; O'Sullivan, JB1
Hellman, B; Idahl, LA1
Hellman, B1
Hostetler, KY; Williams, HR1
Berne, C; Brolin, SE; Isacsson, U1

Reviews

4 review(s) available for nadp and Hyperglycemia

ArticleYear
Considering hyperglycemia and thrombolysis in the Stroke Hyperglycemia Insulin Network Effort (SHINE) trial.
    Annals of the New York Academy of Sciences, 2012, Volume: 1268

    Topics: Animals; Brain Ischemia; Cerebral Hemorrhage; Diabetes Complications; Disease Models, Animal; Fibrinolytic Agents; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; NADP; NADPH Oxidases; Obesity; Recombinant Proteins; Single-Blind Method; Superoxides; Thrombolytic Therapy; Tissue Plasminogen Activator

2012
Hyperglycemia and cardiovascular disease.
    Current atherosclerosis reports, 2001, Volume: 3, Issue:5

    Topics: Blood Glucose; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetic Angiopathies; Glycation End Products, Advanced; Humans; Hyperglycemia; NADP; Oxidative Stress; Postprandial Period; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors

2001
Hyperglycemia, polyol metabolism, and complications of diabetes mellitus.
    Annual review of medicine, 1975, Volume: 26

    Topics: Animals; Blood Glucose; Body Fluids; Cataract; Chemical Phenomena; Chemistry; Diabetes Complications; Fructose; Glucose; Humans; Hyperglycemia; Islets of Langerhans; Kidney; NAD; NADP; Neural Conduction; Oxidoreductases; Rats; Sorbitol; Tibial Nerve

1975
Quantitative histochemistry of glucose metabolism in the islets of Langerhans.
    Current problems in clinical biochemistry, 1971, Volume: 3

    Topics: Adenosine Triphosphate; Animals; Blood Glucose; Citrates; Glucose; Glucosephosphates; Glutamates; Glycogen; Hexokinase; Hexosediphosphates; Hexosephosphates; Hyperglycemia; Islets of Langerhans; Lactates; Methods; Mice; NAD; NADP; Obesity; Organophosphorus Compounds; Pyruvates; Spectrometry, Fluorescence; Uridine Diphosphate Sugars

1971

Trials

1 trial(s) available for nadp and Hyperglycemia

ArticleYear
Considering hyperglycemia and thrombolysis in the Stroke Hyperglycemia Insulin Network Effort (SHINE) trial.
    Annals of the New York Academy of Sciences, 2012, Volume: 1268

    Topics: Animals; Brain Ischemia; Cerebral Hemorrhage; Diabetes Complications; Disease Models, Animal; Fibrinolytic Agents; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; NADP; NADPH Oxidases; Obesity; Recombinant Proteins; Single-Blind Method; Superoxides; Thrombolytic Therapy; Tissue Plasminogen Activator

2012

Other Studies

29 other study(ies) available for nadp and Hyperglycemia

ArticleYear
Glucose availability controls adipogenesis in mouse 3T3-L1 adipocytes via up-regulation of nicotinamide metabolism.
    The Journal of biological chemistry, 2017, 11-10, Volume: 292, Issue:45

    Topics: 3T3-L1 Cells; Adipocytes, White; Adipogenesis; Adiponectin; Adipose Tissue, White; Animals; Biomarkers; Cells, Cultured; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Hyperglycemia; Hypoglycemia; Lipogenesis; Liver X Receptors; Mice; Mice, Inbred C57BL; NAD; NADP; Promoter Regions, Genetic; Stromal Cells; Up-Regulation

2017
Effects of long-acting somatostatin analogues on redox systems in rat lens in experimental diabetes.
    International journal of experimental pathology, 2014, Volume: 95, Issue:2

    Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Glucose; Glutathione; Hyperglycemia; Insulin; Lens, Crystalline; Male; NADP; Octreotide; Oligopeptides; Oxidation-Reduction; Peptides, Cyclic; Rats; Rats, Wistar; Somatostatin

2014
Native fluorescence spectroscopy of blood plasma of rats with experimental diabetes: identifying fingerprints of glucose-related metabolic pathways.
    Journal of biomedical optics, 2015, Volume: 20, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Cross-Linking Reagents; Diabetes Mellitus, Experimental; Fluorescence; Gene Expression Regulation; Glucose; Glycosylation; Hyperglycemia; Male; Metabolic Networks and Pathways; NAD; NADP; Plasma; Rats; Rats, Wistar; Spectrometry, Fluorescence

2015
Effect of SkQ1 on Activity of the Glutathione System and NADPH-Generating Enzymes in an Experimental Model of Hyperglycemia.
    Biochemistry. Biokhimiia, 2015, Volume: 80, Issue:12

    Topics: Animals; Antioxidants; Disease Models, Animal; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hyperglycemia; Isocitrate Dehydrogenase; Liver; Male; Mitochondria; NADP; Oxidation-Reduction; Plastoquinone; Rats; Reactive Oxygen Species

2015
Andrographolide ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated renal oxidative stress and inflammation via Akt/NF-κB pathway.
    Molecular and cellular endocrinology, 2016, 12-05, Volume: 437

    Topics: Animals; Cell Nucleus; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Diterpenes; DNA; Extracellular Matrix; Glucose; Humans; Hyperglycemia; Hypertrophy; Inflammation; Kidney; Kidney Glomerulus; Male; Mesangial Cells; Mice, Inbred C57BL; NADP; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Streptozocin

2016
MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca
    Diabetes, 2017, Volume: 66, Issue:6

    Topics: Animals; Apoptosis; Blotting, Western; Calcium; Calcium-Binding Proteins; Cells, Cultured; Diabetic Cardiomyopathies; Echocardiography; Gene Knockdown Techniques; Glutathione; Glutathione Disulfide; Hyperglycemia; Immunohistochemistry; Mice; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Myocytes, Cardiac; NAD; NADP; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2017
Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Endothelium, Vascular; Fatty Acids, Nonesterified; Gene Expression Regulation, Enzymologic; Glucosephosphate Dehydrogenase; Glutathione; Heart Diseases; Hydrogen Peroxide; Hyperglycemia; Insulin; Isometric Contraction; Mitochondria, Heart; Myocardium; NADP; NADPH Oxidases; Obesity; Rats; Rats, Zucker; Superoxides; Triglycerides; Up-Regulation

2009
Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress.
    Molecules and cells, 2010, Feb-28, Volume: 29, Issue:2

    Topics: Animals; Cell Line; Cytoprotection; Cytosol; Diabetic Nephropathies; Dogs; Enzyme Induction; Glucose; Humans; Hyperglycemia; Isocitrate Dehydrogenase; Kidney Tubules, Proximal; Male; Mice; NADP; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stress, Physiological; Transfection; Up-Regulation

2010
Hyperthermia-induced Hsp90·eNOS preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD activity.
    The Journal of biological chemistry, 2010, Dec-03, Volume: 285, Issue:49

    Topics: Animals; Aorta; Cattle; Down-Regulation; Endothelial Cells; Gene Expression Regulation, Enzymologic; Glucose; Glucose Transporter Type 1; Glucosephosphate Dehydrogenase; Heat-Shock Response; Hot Temperature; HSP90 Heat-Shock Proteins; Hyperglycemia; NADP; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Up-Regulation

2010
Role of hyperglycemia-mediated erythrocyte redox state alteration in the development of diabetic retinopathy.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:1

    Topics: Blood Glucose; Blood Pressure; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Erythrocyte Membrane; Erythrocytes; Female; Fluorescein Angiography; Glucose Tolerance Test; Glutathione; Glycated Hemoglobin; Humans; Hyperglycemia; Lactic Acid; Male; Middle Aged; NAD; NADP; Oxidation-Reduction; Pyruvic Acid

2013
Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.
    Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2

    Topics: Azaserine; Diabetes Mellitus; Glucose; Glycolysis; Hep G2 Cells; Hexosamines; Humans; Hyperglycemia; Membrane Potential, Mitochondrial; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Protein Carbonylation; Reactive Oxygen Species; Thiamine

2013
Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat.
    Life sciences, 2006, Apr-25, Volume: 78, Issue:22

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucosephosphate Dehydrogenase; Glutathione; Hyperglycemia; Liver; Male; NADP; Organ Size; Oxidation-Reduction; Pancreas; Rats; Rats, Sprague-Dawley

2006
Reactive oxygen species and nuclear factor-kappa B pathway mediate high glucose-induced Pax-2 gene expression in mouse embryonic mesenchymal epithelial cells and kidney explants.
    Kidney international, 2006, Volume: 70, Issue:9

    Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Electron Transport Complex I; Epithelium; Gene Expression Regulation, Developmental; Glucose; Hyperglycemia; Kidney; Mesoderm; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADP; NF-kappa B; p38 Mitogen-Activated Protein Kinases; PAX2 Transcription Factor; Protein Kinase C; Reactive Oxygen Species

2006
The effect of phenazine methosulphate on intermediary pathways of glucose metabolism in the lens at different glycaemic levels.
    Experimental eye research, 1995, Volume: 61, Issue:5

    Topics: Animals; Diamide; Glucose; Glycolysis; Hyperglycemia; Lens, Crystalline; Male; Methylphenazonium Methosulfate; NADP; Pentose Phosphate Pathway; Peroxides; Rats; Rats, Wistar; tert-Butylhydroperoxide

1995
Activation of aldose reductase in rat lens and metal-ion chelation by aldose reductase inhibitors and lipoic acid.
    Free radical research, 1996, Volume: 25, Issue:4

    Topics: 1-Octanol; Aldehyde Reductase; Animals; Ascorbic Acid; Chelating Agents; Copper; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Fluorenes; Glucose; Humans; Hydantoins; Hydrogen Peroxide; Hyperglycemia; Imidazoles; Imidazolidines; In Vitro Techniques; Ions; Lens, Crystalline; Lipid Peroxidation; NADP; Octanols; Oxidation-Reduction; Phenanthrolines; Rats; Thioctic Acid

1996
Understanding retinal cytosolic reductive stress.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:7

    Topics: Animals; Cytosol; Diabetic Retinopathy; Hyperglycemia; NAD; NADP; Oxidation-Reduction; Rats; Stress, Physiological

1998
Studies in situ on the effects of hyperglycemia on the C1/C6 ratio and the regulation of fatty acid metabolism in rabbit liver.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1975, May-15, Volume: 51, Issue:1

    Topics: Adenine Nucleotides; Animals; Blood Glucose; Carbon Radioisotopes; Coenzyme A; Fatty Acids; Female; Fructosephosphates; Glucose; Glucosephosphates; Glycerophosphates; Hyperglycemia; Ischemia; Lactates; Liver; NAD; NADP; Phosphates; Portal Vein; Pyruvates; Rabbits; Starvation; Vena Cava, Inferior

1975
Anti-oxidant status in an in vitro model for hyperglycaemic lens cataract formation: competition for available nicotinamide adenine dinucleotide phosphate between glutathione reduction and the polyol pathway.
    Biochemistry international, 1992, Volume: 27, Issue:5

    Topics: Animals; Binding, Competitive; Cataract; Esters; Glutathione; Hydrogen Peroxide; Hyperglycemia; In Vitro Techniques; Male; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Rats; Rats, Wistar; Sorbitol

1992
[Abnormal metabolism of polyol pathway and diabetic complications].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Inositol; NADP; Osmotic Pressure; Polymers

1991
Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells.
    The Journal of biological chemistry, 1989, Dec-15, Volume: 264, Issue:35

    Topics: Adult; Barbital; Erythrocyte Membrane; Glucose; Humans; Hyperglycemia; In Vitro Techniques; Lipid Peroxidation; Membrane Lipids; Models, Biological; NADP; Osmotic Fragility; Oxidation-Reduction; Sorbitol

1989
Activation of aldose reductase from human tissues.
    Diabetes, 1985, Volume: 34, Issue:11

    Topics: Adult; Aged; Aldehyde Reductase; Aorta; Brain; Chromatography, DEAE-Cellulose; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glyceraldehyde; Humans; Hyperglycemia; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Middle Aged; Muscles; NADP; Sugar Alcohol Dehydrogenases

1985
Influence of ischemia on the levels of reduced pyridine nucleotides in the pancreatic islets.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1973, Volume: 5, Issue:2

    Topics: Animals; Hyperglycemia; Ischemia; Islets of Langerhans; Liver; Luciferases; Male; Mice; NAD; NADP; Obesity; Pancreas; Photochemistry; Rats

1973
The mechanism of infection in patients with diabetes mellitus: a review of leukocyte malfunction.
    Surgery, 1974, Volume: 75, Issue:1

    Topics: Acidosis; Animals; Bacterial Infections; Bacteriuria; Diabetes Complications; Diabetes Mellitus; Dogs; Female; Hemagglutination; Humans; Hyperglycemia; Leukocytes; NADP; Phagocytosis; Rabbits; Rats

1974
Studies on the mechanism of L-leucine-and alpha-ketoisocaproic acid-induced insulin release from perifused isolated pancreatic islets.
    Diabetologia, 1974, Volume: 10, Issue:2

    Topics: Animals; Caproates; Chemical Phenomena; Chemistry; Female; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; NADP; Obesity; Spectrometry, Fluorescence; Structure-Activity Relationship; Valerates

1974
The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord.
    Diabetes, 1968, Volume: 17, Issue:5

    Topics: Animals; Axons; Blood Glucose; Cauda Equina; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucose; Glyceraldehyde; Glycosuria; Hyperglycemia; Male; NAD; NADP; Nerve Regeneration; Oxidoreductases; Rabbits; Rats; Schwann Cells; Sciatic Nerve; Sorbitol; Spinal Cord

1968
Presence and mobilization of glycogen in mammalian pancreatic beta cells.
    Endocrinology, 1969, Volume: 84, Issue:1

    Topics: Animals; Cyclic AMP; Fluorometry; Glucagon; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glycogen; Hexokinase; Hyperglycemia; Ischemia; Islets of Langerhans; Mice; NADP; Obesity; Phosphoglucomutase

1969
Some metabolic aspects of the obese-hyperglycemic syndrome in mice.
    Diabetologia, 1967, Volume: 3, Issue:2

    Topics: Adipose Tissue; Animals; Atrophy; Female; Glucose Tolerance Test; Glucuronidase; Hyperglycemia; Isocitrate Dehydrogenase; Liver; Male; Mice; Muscles; NAD; NADP; Obesity; Testis

1967
Effects of hyperglycemia, tolbutamide and glucagon on the pathways of glucose oxidation in the goosefish islet in vitro.
    Diabetes, 1970, Volume: 19, Issue:8

    Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Fishes; Glucagon; Glucose; Hyperglycemia; Islets of Langerhans; NAD; NADP; Nucleotides; Oxygen; Pyridines; Tolbutamide

1970
Photokinetic assay of NADH and NADPH in microdissected tissue samples.
    Analytical biochemistry, 1972, Volume: 50, Issue:1

    Topics: Alcaligenes; Alcohol Oxidoreductases; Animals; Glucosephosphate Dehydrogenase; Glutathione Reductase; Hydroxybutyrate Dehydrogenase; Hyperglycemia; Islets of Langerhans; Kinetics; Liver; Luciferases; Mice; Mice, Inbred Strains; Micromanipulation; NAD; NADP; Obesity; Oscillometry; Oxidation-Reduction; Pancreas; Rhodobacter sphaeroides; Saccharomyces cerevisiae

1972