melatonin has been researched along with Hyperglycemia in 48 studies
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Melatonin is a multifunctional indolamine which counteracts several pathophysiologic steps and displays significant beneficial effects against hyperglycemia-induced cellular toxicity." | 8.84 | Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin. ( Korkmaz, A; Oter, S; Reiter, RJ; Tan, DX; Topal, T, 2008) |
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 8.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| " In the present study, we aimed to examine the protective effect of melatonin against hyperglycemia-induced alterations in the amyloidogenic pathway." | 8.12 | Melatonin Attenuates High Glucose-Induced Changes in Beta Amyloid Precursor Protein Processing in Human Neuroblastoma Cells. ( Boontem, P; Chaopae, W; Govitrapong, P; Nopparat, C; Sopha, P; Wongchitrat, P, 2022) |
| " Melatonin is a strong anti-inflammatory hormone, mediating the cytoprotective effect of a variety of retinal cells against hyperglycemia." | 7.96 | Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy. ( Chen, L; Liu, W; Liu, X; Shi, Q; Song, E; Sun, Y; Tu, Y; Wang, K; Wang, X; Wang, Z; Zhao, Q; Zhu, M, 2020) |
| "This study sought to investigate a novel effect of melatonin in reducing brain injury in an in vivo hyperglycemic intracerebral hemorrhage (ICH) model and further explore the mechanisms of protection." | 7.96 | Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats. ( Liang, F; Shi, L; Sun, Z; Wang, J; Wang, Z; Xu, S; Zhang, J; Zheng, J; Zhou, J; Zhu, X, 2020) |
| "The effects of melatonin, aluminum oxide, and polymethylsiloxane complex on the expression of LYVE-1 (lymphatic vessel endothelial hyaluronan receptor) in the liver were studied in db/db mice with experimental obesity and type 2 diabetes mellitus." | 7.83 | Effects of Melatonin, Aluminum Oxide, and Polymethylsiloxane Complex on the Expression of LYVE-1 in the Liver of Mice with Obesity and Type 2 Diabetes Mellitus. ( Arkhipov, SA; Ishchenko, IY; Klimontov, VV; Konenkov, VI; Michurina, SV; Rachkovskaya, LN; Zavyalov, EL, 2016) |
| "The present results suggest that melatonin prevents the well-recognized increase in glucose levels that usually follows exposure to intermittent hypoxia." | 7.81 | Melatonin prevents hyperglycemia in a model of sleep apnea. ( Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP, 2015) |
| "The antioxidative effects of melatonin (Mel), 5-hydroxytryptophan (5-HTP) and taurine (TAU) on hyperglycemia-induced oxidative stress was investigated in primary cultures of kidney-cortex tubule cells grown in metabolically and hormonally defined medium." | 7.74 | Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. ( Bryla, J; Derlacz, RA; Drozak, J; Piekutowska, A; Sliwinska, M; Winiarska, K, 2007) |
| "Gestational diabetes mellitus is an important public health problem and has been associated with the development of pregnancy-specific urinary incontinence." | 7.01 | Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus. ( Barbosa, AMP; França, DCH; França, EL; Honorio-França, AC; Rudge, MVC; Sobrevia, L, 2023) |
| " Additionally, due to its variable absorption and poor oral bioavailability necessitates the development of alternative delivery methods." | 5.91 | Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats. ( Abdelaziz, M; Alaa, H; El-Karamany, Y; Farid, A; Magdy, S; Mansour, M; Mohsen, S; Mustafa, M, 2023) |
| "Melatonin treatment reversed the harmful effects of hyperglycemia on EPC through adenosine monophosphate-activated protein kinase-related mechanisms to increase eNOS phosphorylation and heme oxygenase-1 expression." | 5.72 | Melatonin Improves Ischemia-Induced Circulation Recovery Impairment in Mice with Streptozotocin-Induced Diabetes by Improving the Endothelial Progenitor Cells Functioning. ( Chen, CY; Chou, RH; Huang, HL; Huang, PH; Kuo, CS; Lin, SJ; Tsai, HY; Wei, JH, 2022) |
| "Melatonin treatment significantly preserved the functions of both pancreas and liver by reducing β cell apoptosis, CD68-cell infiltration, ROS production, and caspase-3 expression." | 5.48 | Melatonin attenuates smoking-induced hyperglycemia via preserving insulin secretion and hepatic glycogen synthesis in rats. ( Di, X; Lai, Z; Li, T; Liu, C; Liu, X; Ni, L; Song, X; Wang, X; Xie, Z; Zhang, R; Zhao, Z, 2018) |
| "Melatonin is a neurohormone that works as a nighttime signal for circadian integrity and health maintenance." | 5.40 | Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia. ( Afeche, SC; Amaral, FG; Barone, M; Bordin, S; Cipolla-Neto, J; do Carmo Buonfiglio, D; Lima, L; Menna-Barreto, L; Peliciari-Garcia, RA; Peres, R; Reiter, RJ; Scavone, C; Scialfa, JH; Turati, AO, 2014) |
| " There has also been a marked increase in the prevalence of metabolic syndrome in recent decades, which has been associated with a reduction in nocturnal pineal production of melatonin with aging and an increased risk of coronary diseases, type 2 diabetes mellitus (T2DM) and death." | 4.90 | Melatonin and metabolic regulation: a review. ( A-Serrano, MM; Acuña-Castroviejo, D; Agil, A; Blanca-Herrera, RM; Fernández-Vázquez, G; Navarro-Alarcón, M; Ruiz-Ojeda, FJ, 2014) |
| " Melatonin is a multifunctional indolamine which counteracts several pathophysiologic steps and displays significant beneficial effects against hyperglycemia-induced cellular toxicity." | 4.84 | Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin. ( Korkmaz, A; Oter, S; Reiter, RJ; Tan, DX; Topal, T, 2008) |
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 4.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| " In the present study, we aimed to examine the protective effect of melatonin against hyperglycemia-induced alterations in the amyloidogenic pathway." | 4.12 | Melatonin Attenuates High Glucose-Induced Changes in Beta Amyloid Precursor Protein Processing in Human Neuroblastoma Cells. ( Boontem, P; Chaopae, W; Govitrapong, P; Nopparat, C; Sopha, P; Wongchitrat, P, 2022) |
| " This is due to hyperglycemia, the higher prevalence of sleep disorders and also the low levels of melatonin, a substance with anti-inflammatory actions, in these patients." | 4.02 | Possible role of exogenous melatonin in preventing more serious COVID-19 infection in patients with type 2 diabetes mellitus. ( Martorina, WJ; Tavares, A, 2021) |
| " Melatonin is a strong anti-inflammatory hormone, mediating the cytoprotective effect of a variety of retinal cells against hyperglycemia." | 3.96 | Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy. ( Chen, L; Liu, W; Liu, X; Shi, Q; Song, E; Sun, Y; Tu, Y; Wang, K; Wang, X; Wang, Z; Zhao, Q; Zhu, M, 2020) |
| "This study sought to investigate a novel effect of melatonin in reducing brain injury in an in vivo hyperglycemic intracerebral hemorrhage (ICH) model and further explore the mechanisms of protection." | 3.96 | Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats. ( Liang, F; Shi, L; Sun, Z; Wang, J; Wang, Z; Xu, S; Zhang, J; Zheng, J; Zhou, J; Zhu, X, 2020) |
| "The effects of melatonin, aluminum oxide, and polymethylsiloxane complex on the expression of LYVE-1 (lymphatic vessel endothelial hyaluronan receptor) in the liver were studied in db/db mice with experimental obesity and type 2 diabetes mellitus." | 3.83 | Effects of Melatonin, Aluminum Oxide, and Polymethylsiloxane Complex on the Expression of LYVE-1 in the Liver of Mice with Obesity and Type 2 Diabetes Mellitus. ( Arkhipov, SA; Ishchenko, IY; Klimontov, VV; Konenkov, VI; Michurina, SV; Rachkovskaya, LN; Zavyalov, EL, 2016) |
| "The present results suggest that melatonin prevents the well-recognized increase in glucose levels that usually follows exposure to intermittent hypoxia." | 3.81 | Melatonin prevents hyperglycemia in a model of sleep apnea. ( Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP, 2015) |
| "Hyperglycemia increased retinal oxidation as measured through levels of nitrotyrosine and malondialdehyde." | 3.80 | Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats. ( Bakariş, S; Durdu, H; Ergün, Y; Ganiyusufoğlu, E; Kılınç, M; Ozdemir, G, 2014) |
| "Due to its antioxidant and antiapoptotic action, melatonin was able to mitigate, but not prevent acute tubular necrosis in rats with hyperglycemia under anesthesia by isoflurane." | 3.80 | Evaluation of renal protection from high doses of melatonin in an experimental model of renal ischemia and reperfusion in hyperglycemic rats. ( Castiglia, YM; de Carvalho, LR; de Souza, AV; Deffune, E; Domingues, MA; Golim, MA; Vianna, IG; Vianna, PT, 2014) |
| "The aim of this study was to investigate the effects of melatonin on glucose homeostasis in young male Zucker diabetic fatty (ZDF) rats, an experimental model of metabolic syndrome and type 2 diabetes mellitus (T2DM)." | 3.78 | Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats. ( Agil, A; Fernández-Vázquez, G; Figueroa, A; Rosado, I; Ruiz, R; Zen, N, 2012) |
| "The antioxidative effects of melatonin (Mel), 5-hydroxytryptophan (5-HTP) and taurine (TAU) on hyperglycemia-induced oxidative stress was investigated in primary cultures of kidney-cortex tubule cells grown in metabolically and hormonally defined medium." | 3.74 | Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. ( Bryla, J; Derlacz, RA; Drozak, J; Piekutowska, A; Sliwinska, M; Winiarska, K, 2007) |
| "Gestational diabetes mellitus is an important public health problem and has been associated with the development of pregnancy-specific urinary incontinence." | 3.01 | Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus. ( Barbosa, AMP; França, DCH; França, EL; Honorio-França, AC; Rudge, MVC; Sobrevia, L, 2023) |
| "Melatonin is a multifunctional indoleamine which counteracts several pathophysiologic steps and displays significant beneficial effects against hyperglycemia-induced cellular toxicity." | 2.48 | Glucose: a vital toxin and potential utility of melatonin in protecting against the diabetic state. ( Korkmaz, A; Ma, S; Reiter, RJ; Rosales-Corral, S; Tan, DX; Topal, T, 2012) |
| " Additionally, due to its variable absorption and poor oral bioavailability necessitates the development of alternative delivery methods." | 1.91 | Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats. ( Abdelaziz, M; Alaa, H; El-Karamany, Y; Farid, A; Magdy, S; Mansour, M; Mohsen, S; Mustafa, M, 2023) |
| "Melatonin treatment reversed the harmful effects of hyperglycemia on EPC through adenosine monophosphate-activated protein kinase-related mechanisms to increase eNOS phosphorylation and heme oxygenase-1 expression." | 1.72 | Melatonin Improves Ischemia-Induced Circulation Recovery Impairment in Mice with Streptozotocin-Induced Diabetes by Improving the Endothelial Progenitor Cells Functioning. ( Chen, CY; Chou, RH; Huang, HL; Huang, PH; Kuo, CS; Lin, SJ; Tsai, HY; Wei, JH, 2022) |
| "Melatonin treatment ameliorated hyperglycaemia-induced impairment of Leydig cell function with simultaneous stimulation of 5'-adenosine monophosphate activated protein kinase (AMPK)/SIRT1 activity and the expression of autophagy-related genes." | 1.72 | Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway. ( Lin, S; Lv, Z; Wang, P; Zhang, S, 2022) |
| "Melatonin is a hormone known as having very strong anti-oxidant property." | 1.56 | Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. ( Jang, JE; Jung, HS; Kim, MK; Kim, TN; Kwon, MJ; Lee, SH; Lee, YH; Park, JH, 2020) |
| "Melatonin was decreased (124." | 1.48 | Melatonin levels in human diabetic dental pulp tissue and its effects on dental pulp cells under hyperglycaemic conditions. ( Brković, B; DJukić, L; DŽeletović, B; Milašin, J; Milosavljević, A; Roganović, J; Toljić, B, 2018) |
| "Melatonin treatment significantly preserved the functions of both pancreas and liver by reducing β cell apoptosis, CD68-cell infiltration, ROS production, and caspase-3 expression." | 1.48 | Melatonin attenuates smoking-induced hyperglycemia via preserving insulin secretion and hepatic glycogen synthesis in rats. ( Di, X; Lai, Z; Li, T; Liu, C; Liu, X; Ni, L; Song, X; Wang, X; Xie, Z; Zhang, R; Zhao, Z, 2018) |
| "Hyperglycemia is a representative hallmark and risk factor for diabetes and is closely linked to diabetes associated complications." | 1.48 | Protective Role of Melatonin in Streptozotocin Induced Pancreatic Damages in Diabetic Wistar Rat. ( Ahmad Hajam, Y; Basheer, M; Ghosh, H; Rai, S; Singh, S, 2018) |
| "Melatonin was injected intraperitoneally at a dose of 50 mg/kg/day for 56 days to group 3 and group 4." | 1.48 | Melatonin protects against streptozotocin-induced diabetic cardiomyopathy by the phosphorylation of vascular endothelial growth factor-A (VEGF-A). ( Behram Kandemir, Y; Bozdemir, MN; Guntekin, Ü; Korucuk, N; Tosun, V, 2018) |
| "Melatonin treatment effectively ameliorated MI/R injury by reducing infarct size, myocardial apoptosis, and oxidative stress." | 1.46 | Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner. ( Fan, C; Li, Z; Wang, H; Xu, Y; Xue, X; Yang, Y; Yu, L; Zhang, J; Zhao, G, 2017) |
| "Treatment of melatonin, rats had shorter escape latencies and remained in the target quadrant longer compared to the HFD-fed and STZ-treated rats." | 1.43 | Melatonin attenuates the high-fat diet and streptozotocin-induced reduction in rat hippocampal neurogenesis. ( Govitrapong, P; Kamsrijai, U; Lansubsakul, N; Mukda, S; Sae-Ung, K; Wongchitrat, P, 2016) |
| "Melatonin is a neurohormone that works as a nighttime signal for circadian integrity and health maintenance." | 1.40 | Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia. ( Afeche, SC; Amaral, FG; Barone, M; Bordin, S; Cipolla-Neto, J; do Carmo Buonfiglio, D; Lima, L; Menna-Barreto, L; Peliciari-Garcia, RA; Peres, R; Reiter, RJ; Scavone, C; Scialfa, JH; Turati, AO, 2014) |
| "Melatonin concentration was higher in colostrum samples from hyperglycemic than normoglycemic mothers." | 1.39 | Antioxidant effect of melatonin on the functional activity of colostral phagocytes in diabetic women. ( Calderon, IM; Fagundes, DL; França, EL; Honorio-França, AC; Morceli, G, 2013) |
| "Melatonin is a potent antioxidant capable of protecting variety of retinal cells from oxidative damage." | 1.38 | Melatonin-mediated cytoprotection against hyperglycemic injury in Müller cells. ( Cai, J; Chang, Q; Jiang, T; Wang, L; Xu, G; Yan, S; Zhao, Z, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.08) | 18.7374 |
| 1990's | 3 (6.25) | 18.2507 |
| 2000's | 9 (18.75) | 29.6817 |
| 2010's | 24 (50.00) | 24.3611 |
| 2020's | 11 (22.92) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, P | 1 |
| Zhang, S | 1 |
| Lin, S | 1 |
| Lv, Z | 1 |
| Kuo, CS | 1 |
| Chen, CY | 1 |
| Huang, HL | 1 |
| Tsai, HY | 1 |
| Chou, RH | 1 |
| Wei, JH | 1 |
| Huang, PH | 1 |
| Lin, SJ | 1 |
| França, DCH | 1 |
| França, EL | 2 |
| Sobrevia, L | 1 |
| Barbosa, AMP | 1 |
| Honorio-França, AC | 2 |
| Rudge, MVC | 1 |
| Xu, Q | 1 |
| Cheung, RTF | 1 |
| Alaa, H | 1 |
| Abdelaziz, M | 1 |
| Mustafa, M | 1 |
| Mansour, M | 1 |
| Magdy, S | 1 |
| Mohsen, S | 1 |
| El-Karamany, Y | 1 |
| Farid, A | 1 |
| Tu, Y | 1 |
| Zhu, M | 1 |
| Wang, Z | 2 |
| Wang, K | 1 |
| Chen, L | 1 |
| Liu, W | 1 |
| Shi, Q | 1 |
| Zhao, Q | 1 |
| Sun, Y | 1 |
| Wang, X | 3 |
| Song, E | 1 |
| Liu, X | 2 |
| Lee, YH | 1 |
| Jung, HS | 1 |
| Kwon, MJ | 1 |
| Jang, JE | 1 |
| Kim, TN | 1 |
| Lee, SH | 1 |
| Kim, MK | 1 |
| Park, JH | 1 |
| Liang, F | 1 |
| Wang, J | 4 |
| Zhu, X | 2 |
| Zheng, J | 1 |
| Sun, Z | 1 |
| Xu, S | 1 |
| Zhang, J | 3 |
| Zhou, J | 1 |
| Shi, L | 1 |
| Nopparat, C | 1 |
| Chaopae, W | 1 |
| Boontem, P | 1 |
| Sopha, P | 1 |
| Wongchitrat, P | 2 |
| Govitrapong, P | 2 |
| Shao, A | 1 |
| Gao, S | 1 |
| Wu, H | 1 |
| Xu, W | 1 |
| Pan, Y | 2 |
| Fang, Y | 1 |
| Martorina, WJ | 1 |
| Tavares, A | 1 |
| Li, T | 1 |
| Ni, L | 1 |
| Zhao, Z | 2 |
| Lai, Z | 1 |
| Di, X | 1 |
| Xie, Z | 1 |
| Song, X | 1 |
| Zhang, R | 1 |
| Liu, C | 1 |
| Milosavljević, A | 1 |
| DJukić, L | 1 |
| Toljić, B | 1 |
| Milašin, J | 1 |
| DŽeletović, B | 1 |
| Brković, B | 1 |
| Roganović, J | 1 |
| Kadry, SM | 1 |
| El-Dakdoky, MH | 1 |
| Haggag, NZ | 1 |
| Rashed, LA | 1 |
| Hassen, MT | 1 |
| Gurel-Gokmen, B | 1 |
| Ipekci, H | 1 |
| Oktay, S | 1 |
| Alev, B | 1 |
| Ustundag, UV | 1 |
| Ak, E | 1 |
| Akakın, D | 1 |
| Sener, G | 1 |
| Emekli-Alturfan, E | 1 |
| Yarat, A | 1 |
| Tunali-Akbay, T | 1 |
| Behram Kandemir, Y | 1 |
| Guntekin, Ü | 1 |
| Tosun, V | 1 |
| Korucuk, N | 1 |
| Bozdemir, MN | 1 |
| Li, H | 1 |
| Zhang, Y | 2 |
| Liu, S | 2 |
| Li, F | 1 |
| Wang, B | 1 |
| Cao, L | 1 |
| Xia, T | 1 |
| Yao, Q | 1 |
| Chen, H | 1 |
| Li, Y | 1 |
| Li, G | 1 |
| Li, X | 1 |
| Ni, S | 1 |
| Ahmad Hajam, Y | 1 |
| Rai, S | 1 |
| Basheer, M | 1 |
| Ghosh, H | 1 |
| Singh, S | 1 |
| Morceli, G | 1 |
| Fagundes, DL | 1 |
| Calderon, IM | 1 |
| Amaral, FG | 1 |
| Turati, AO | 1 |
| Barone, M | 1 |
| Scialfa, JH | 1 |
| do Carmo Buonfiglio, D | 1 |
| Peres, R | 1 |
| Peliciari-Garcia, RA | 1 |
| Afeche, SC | 1 |
| Lima, L | 1 |
| Scavone, C | 1 |
| Bordin, S | 1 |
| Reiter, RJ | 3 |
| Menna-Barreto, L | 1 |
| Cipolla-Neto, J | 1 |
| de Souza, AV | 1 |
| Golim, MA | 1 |
| Deffune, E | 1 |
| Domingues, MA | 1 |
| de Carvalho, LR | 1 |
| Vianna, IG | 1 |
| Castiglia, YM | 1 |
| Vianna, PT | 1 |
| Ozdemir, G | 1 |
| Ergün, Y | 1 |
| Bakariş, S | 1 |
| Kılınç, M | 1 |
| Durdu, H | 1 |
| Ganiyusufoğlu, E | 1 |
| Navarro-Alarcón, M | 1 |
| Ruiz-Ojeda, FJ | 1 |
| Blanca-Herrera, RM | 1 |
| A-Serrano, MM | 1 |
| Acuña-Castroviejo, D | 1 |
| Fernández-Vázquez, G | 2 |
| Agil, A | 2 |
| Kaminski, RS | 1 |
| Martinez, D | 1 |
| Fagundes, M | 1 |
| Martins, EF | 1 |
| Montanari, CC | 1 |
| Rosa, DP | 1 |
| Fiori, CZ | 1 |
| Marroni, NP | 1 |
| Kahya, MC | 1 |
| Naziroğlu, M | 1 |
| Çiğ, B | 1 |
| Gobbo, MG | 1 |
| Dizeyi, N | 1 |
| Abrahamsson, PA | 1 |
| Bertilsson, PA | 1 |
| Masitéli, VS | 1 |
| Pytlowanciv, EZ | 1 |
| Taboga, SR | 1 |
| Góes, RM | 1 |
| Guo, Y | 1 |
| Yuan, Q | 1 |
| Wang, L | 2 |
| Liu, Q | 1 |
| Wang, F | 1 |
| Hao, A | 1 |
| Lansubsakul, N | 1 |
| Kamsrijai, U | 1 |
| Sae-Ung, K | 1 |
| Mukda, S | 1 |
| Yu, L | 1 |
| Fan, C | 1 |
| Li, Z | 1 |
| Xue, X | 1 |
| Xu, Y | 1 |
| Zhao, G | 1 |
| Yang, Y | 1 |
| Wang, H | 1 |
| Michurina, SV | 1 |
| Ishchenko, IY | 1 |
| Arkhipov, SA | 1 |
| Klimontov, VV | 1 |
| Rachkovskaya, LN | 1 |
| Konenkov, VI | 1 |
| Zavyalov, EL | 1 |
| Korkmaz, A | 2 |
| Topal, T | 2 |
| Oter, S | 1 |
| Tan, DX | 2 |
| Sainath, SB | 1 |
| Reddy, PS | 1 |
| Rosado, I | 1 |
| Ruiz, R | 1 |
| Figueroa, A | 1 |
| Zen, N | 1 |
| Ma, S | 1 |
| Rosales-Corral, S | 1 |
| Korkmaz, GG | 1 |
| Uzun, H | 1 |
| Cakatay, U | 1 |
| Aydin, S | 1 |
| Jiang, T | 1 |
| Chang, Q | 1 |
| Yan, S | 1 |
| Cai, J | 1 |
| Xu, G | 1 |
| Stetinová, V | 1 |
| Smetanová, L | 1 |
| Grossmann, V | 1 |
| Anzenbacher, P | 1 |
| Kocic, G | 1 |
| Djordjevic, V | 1 |
| Vlahovic, P | 1 |
| Kocic, R | 1 |
| Pavlovic, D | 1 |
| Jevtovic, T | 1 |
| Guven, A | 1 |
| Yavuz, O | 1 |
| Cam, M | 1 |
| Ercan, F | 1 |
| Bukan, N | 1 |
| Comunoglu, C | 1 |
| Gokce, F | 1 |
| Kafl, HE | 1 |
| Elkashef, HA | 1 |
| Derlacz, RA | 1 |
| Sliwinska, M | 1 |
| Piekutowska, A | 1 |
| Winiarska, K | 1 |
| Drozak, J | 1 |
| Bryla, J | 1 |
| Cano, P | 1 |
| Jiménez-Ortega, V | 1 |
| Larrad, A | 1 |
| Reyes Toso, CF | 1 |
| Cardinali, DP | 1 |
| Esquifino, AI | 1 |
| Boden, G | 1 |
| Ruiz, J | 1 |
| Urbain, JL | 1 |
| Chen, X | 1 |
| Shima, T | 1 |
| Chun, SJ | 1 |
| Niijima, A | 1 |
| Bizot-Espiard, JG | 2 |
| Guardiola-Lemaitre, B | 2 |
| Hosokawa, M | 1 |
| Nagai, K | 1 |
| Doublé, A | 1 |
| Delagrange, P | 1 |
| Ktorza, A | 1 |
| Pénicaud, L | 1 |
| Abdel-Wahab, MH | 1 |
| Abd-Allah, AR | 1 |
| Andersson, AK | 1 |
| Sandler, S | 1 |
| Bailey, CJ | 1 |
| Atkins, TW | 1 |
| Matty, AJ | 1 |
4 reviews available for melatonin and Hyperglycemia
| Article | Year |
|---|---|
Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus.
Topics: Cytokines; Diabetes, Gestational; Female; Humans; Hyperglycemia; Melatonin; Nutrigenomics; Pregnancy | 2023 |
Melatonin and metabolic regulation: a review.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hyperglycemia; M | 2014 |
Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin.
Topics: Animals; Humans; Hyperglycemia; Melatonin; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive | 2008 |
Glucose: a vital toxin and potential utility of melatonin in protecting against the diabetic state.
Topics: Adipocytes; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diabetes Mellitus, Type | 2012 |
44 other studies available for melatonin and Hyperglycemia
| Article | Year |
|---|---|
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Ley | 2022 |
Melatonin Improves Ischemia-Induced Circulation Recovery Impairment in Mice with Streptozotocin-Induced Diabetes by Improving the Endothelial Progenitor Cells Functioning.
Topics: Animals; Diabetes Mellitus, Experimental; Endothelial Progenitor Cells; Hindlimb; Humans; Hydrogen P | 2022 |
Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Diabetes Mellitus, Type 1; Hyperglycemia; Infarction, | 2023 |
Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Chitosan; Diabetes Mellitus, Experimental; Humans; Hyperglycem | 2023 |
Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy.
Topics: Animals; Apoptosis; Cytokines; Diabetes Mellitus; Diabetic Retinopathy; Ependymoglial Cells; Hypergl | 2020 |
Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity.
Topics: Animals; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cellular Senescence; Hyperglyce | 2020 |
Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Hyperglycemia; Injections, Intraperitoneal; Ma | 2020 |
Melatonin Attenuates High Glucose-Induced Changes in Beta Amyloid Precursor Protein Processing in Human Neuroblastoma Cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2022 |
Melatonin Ameliorates Hemorrhagic Transformation via Suppression of ROS-Induced NLRP3 Activation after Cerebral Ischemia in Hyperglycemic Rats.
Topics: Animals; Brain Ischemia; Hematoma, Subdural, Intracranial; Hyperglycemia; Male; Melatonin; NLR Famil | 2021 |
Possible role of exogenous melatonin in preventing more serious COVID-19 infection in patients with type 2 diabetes mellitus.
Topics: COVID-19; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Melatonin; SARS-CoV-2 | 2021 |
Melatonin attenuates smoking-induced hyperglycemia via preserving insulin secretion and hepatic glycogen synthesis in rats.
Topics: Animals; Hyperglycemia; Insulin; Insulin Secretion; Liver; Liver Glycogen; Male; Melatonin; Pancreas | 2018 |
Melatonin levels in human diabetic dental pulp tissue and its effects on dental pulp cells under hyperglycaemic conditions.
Topics: Aged; Case-Control Studies; Dental Pulp; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assa | 2018 |
Melatonin improves the therapeutic role of mesenchymal stem cells in diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bone Marrow Cells; Cell Proliferation; Cells, Cultured | 2018 |
Melatonin improves hyperglycemia induced damages in rat brain.
Topics: Animals; Antioxidants; Brain; Brain Diseases, Metabolic; Diabetes Mellitus, Experimental; Diabetic N | 2018 |
Melatonin protects against streptozotocin-induced diabetic cardiomyopathy by the phosphorylation of vascular endothelial growth factor-A (VEGF-A).
Topics: Animals; Antioxidants; Blood Glucose; Cardiotonic Agents; Coronary Vessels; Diabetic Cardiomyopathie | 2018 |
Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia.
Topics: Autophagy; Cell Differentiation; Cell Proliferation; Hyperglycemia; Melatonin; Neural Stem Cells; Si | 2019 |
Protective Role of Melatonin in Streptozotocin Induced Pancreatic Damages in Diabetic Wistar Rat.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; I | 2018 |
Antioxidant effect of melatonin on the functional activity of colostral phagocytes in diabetic women.
Topics: Adolescent; Adult; Antioxidants; Calcium; Colostrum; Cross-Sectional Studies; Escherichia coli; Fema | 2013 |
Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Cell Survival; Diabetes Mellitus, Experimental; Humans; | 2014 |
Evaluation of renal protection from high doses of melatonin in an experimental model of renal ischemia and reperfusion in hyperglycemic rats.
Topics: Animals; Dose-Response Relationship, Drug; Hyperglycemia; Kidney; Male; Melatonin; Rats; Rats, Wista | 2014 |
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopa | 2014 |
Melatonin prevents hyperglycemia in a model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Disease Models, Anim | 2015 |
Melatonin and selenium reduce plasma cytokine and brain oxidative stress levels in diabetic rats.
Topics: Animals; Antioxidants; Brain; Cytokines; Diabetes Mellitus, Experimental; Female; Glutathione Peroxi | 2015 |
Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Cell Line, Tumor; Cell Proliferation; Cel | 2015 |
Melatonin prevents neural tube defects in the offspring of diabetic pregnancy.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Experimental; Female; Hyperglycemia; Melatonin; Mice | 2015 |
Melatonin attenuates the high-fat diet and streptozotocin-induced reduction in rat hippocampal neurogenesis.
Topics: Animals; Diet, High-Fat; Doublecortin Protein; Hippocampus; Hyperglycemia; Male; Melatonin; Memory; | 2016 |
Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner.
Topics: Animals; Blotting, Western; Disease Models, Animal; Fluorescent Antibody Technique; Hyperglycemia; M | 2017 |
Effects of Melatonin, Aluminum Oxide, and Polymethylsiloxane Complex on the Expression of LYVE-1 in the Liver of Mice with Obesity and Type 2 Diabetes Mellitus.
Topics: Aluminum Oxide; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Ani | 2016 |
Melatonergic regulation of hemolymph sugar levels in the freshwater edible crab, Oziotelphusa senex senex.
Topics: Animals; Brachyura; Carbohydrate Metabolism; Carbohydrates; Glycogen; Hemolymph; Homeostasis; Hyperg | 2010 |
Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids, Nonesterified | 2012 |
Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; DNA Damage; Enzyme-Linked Immun | 2012 |
Melatonin-mediated cytoprotection against hyperglycemic injury in Müller cells.
Topics: Animals; Base Sequence; DNA Primers; Hyperglycemia; Melatonin; Neuroglia; Rats; Rats, Sprague-Dawley | 2012 |
In vitro and in vivo assessment of the antioxidant activity of melatonin and related indole derivatives.
Topics: Alloxan; Animals; Antioxidants; Carboxylic Acids; Female; Hyaluronic Acid; Hyperglycemia; In Vitro T | 2002 |
Antioxidants modulate adenosine metabolism in rat mesangial cells cultured under high glucose conditions.
Topics: Adenosine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Cell Culture | 2002 |
Effects of melatonin on streptozotocin-induced diabetic liver injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; L | 2006 |
Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; En | 2006 |
Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury.
Topics: 5-Hydroxytryptophan; Animals; Hyperglycemia; Kidney Cortex; Kidney Diseases; Kidney Tubules; Male; M | 2007 |
Effect of a high-fat diet on 24-h pattern of circulating levels of prolactin, luteinizing hormone, testosterone, corticosterone, thyroid-stimulating hormone and glucose, and pineal melatonin content, in rats.
Topics: Animals; Blood Glucose; Body Weight; Circadian Rhythm; Corticosterone; Diet; Dietary Fats; Hormones; | 2008 |
Evidence for a circadian rhythm of insulin secretion.
Topics: Adult; Blood Glucose; C-Peptide; Circadian Rhythm; Female; Glucose Clamp Technique; Humans; Hydrocor | 1996 |
Melatonin suppresses hyperglycemia caused by intracerebroventricular injection of 2-deoxy-D-glucose in rats.
Topics: Animals; Blood Glucose; Cerebral Ventricles; Deoxyglucose; Glucagon; Hyperglycemia; Injections, Intr | 1997 |
Diurnal rhythms in plasma glucose, insulin, growth hormone and melatonin levels in fasted and hyperglycaemic rats.
Topics: Animals; Blood Glucose; Circadian Rhythm; Fasting; Growth Hormone; Hyperglycemia; Insulin; Male; Mel | 1998 |
Possible protective effect of melatonin and/or desferrioxamine against streptozotocin-induced hyperglycaemia in mice.
Topics: Animals; Blood Glucose; Deferoxamine; Glutathione; Hyperglycemia; Lipid Peroxidation; Lipids; Male; | 2000 |
Melatonin protects against streptozotocin, but not interleukin-1beta-induced damage of rodent pancreatic beta-cells.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glucose; Hypergl | 2001 |
Melatonin inhibition of insulin secretion in the rat and mouse.
Topics: Animals; Blood Glucose; Depression, Chemical; Glucose; Glucose Tolerance Test; Hyperglycemia; Insuli | 1974 |