bupivacaine has been researched along with Hyperglycemia in 5 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anesthetic bupivacaine (Bup) has been reported to induce neurotoxicity mediated by reactive oxygen species (ROS), which is aggravated by hyperglycemia." | 8.02 | KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity. ( Lai, L; Lei, H; Li, H; Li, L; Weng, Y; Xu, S; Zhang, Y, 2021) |
| " The anesthetic bupivacaine (Bup) has been reported to induce neurotoxicity mediated by reactive oxygen species (ROS), which is aggravated by hyperglycemia." | 4.02 | KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity. ( Lai, L; Lei, H; Li, H; Li, L; Weng, Y; Xu, S; Zhang, Y, 2021) |
| "Levobupivacaine was more potent than lidocaine in all tests employed on diabetic rats." | 1.39 | Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy. ( Gunay, I; Gunes, Y; Mert, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Weng, Y | 1 |
| Lai, L | 1 |
| Lei, H | 1 |
| Xu, S | 1 |
| Zhang, Y | 1 |
| Li, L | 2 |
| Ye, XP | 1 |
| Lu, AZ | 1 |
| Zhou, SQ | 1 |
| Liu, H | 1 |
| Liu, ZJ | 1 |
| Jiang, S | 1 |
| Xu, SY | 1 |
| Mert, T | 1 |
| Gunes, Y | 1 |
| Gunay, I | 1 |
| Kiliçkan, L | 1 |
| Yumuk, Z | 1 |
| Bayindir, O | 1 |
| Hahn, RG | 1 |
2 trials available for bupivacaine and Hyperglycemia
| Article | Year |
|---|---|
The effect of combined preinduction thoracic epidural anaesthesia and glucocorticoid administration on perioperative interleukin-10 levels and hyperglycemia. A randomized controlled trial.
Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Blood Glucose; Bupivacaine; Cardiopulmonary Bypass; | 2008 |
Increased haemodilution in hypotension induced by epidural anaesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, Spinal; Blood Glucose; Blood Pressure; Bl | 1993 |
3 other studies available for bupivacaine and Hyperglycemia
| Article | Year |
|---|---|
KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity.
Topics: Bupivacaine; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Humans; Hyperglycemia; Krupp | 2021 |
Hyperglycemia magnifies bupivacaine-induced cell apoptosis triggered by mitochondria dysfunction and endoplasmic reticulum stress.
Topics: Anesthetics, Local; Apoptosis; Blotting, Western; Bupivacaine; Cell Survival; Endoplasmic Reticulum | 2013 |
Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy.
Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Disease Models, Animal; F | 2013 |