pd 98059 has been researched along with Hyperglycemia in 10 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin is a potential anticancer agent for pancreatic cancer." | 5.51 | Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways. ( Cao, L; Han, L; Li, W; Ma, Q; Wang, Z; Wu, Z; Xiao, X, 2019) |
| "Human pancreatic cancer Panc-1 cells were exposed to high glucose condition with or without resveratrol, N-acetylcysteine (NAC, a scavenger of free radicals), PD 98059 (an ERK inhibitor) or SB 203580 (a p38 MAPK inhibitor)." | 5.43 | Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways. ( Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X, 2016) |
| "Curcumin is a potential anticancer agent for pancreatic cancer." | 1.51 | Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways. ( Cao, L; Han, L; Li, W; Ma, Q; Wang, Z; Wu, Z; Xiao, X, 2019) |
| "Human pancreatic cancer Panc-1 cells were exposed to high glucose condition with or without resveratrol, N-acetylcysteine (NAC, a scavenger of free radicals), PD 98059 (an ERK inhibitor) or SB 203580 (a p38 MAPK inhibitor)." | 1.43 | Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways. ( Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W | 2 |
| Wang, Z | 1 |
| Xiao, X | 2 |
| Han, L | 1 |
| Wu, Z | 1 |
| Ma, Q | 2 |
| Cao, L | 2 |
| Chen, X | 1 |
| Zhou, J | 1 |
| Ni, X | 1 |
| Huang, X | 1 |
| Yao, J | 1 |
| He, Q | 1 |
| Wang, K | 1 |
| Duan, T | 1 |
| Cazarolli, LH | 1 |
| Folador, P | 1 |
| Moresco, HH | 1 |
| Brighente, IM | 1 |
| Pizzolatti, MG | 1 |
| Silva, FR | 1 |
| Liu, W | 1 |
| Lan, T | 1 |
| Xie, X | 1 |
| Huang, K | 1 |
| Peng, J | 1 |
| Huang, J | 1 |
| Shen, X | 1 |
| Liu, P | 1 |
| Huang, H | 1 |
| She, T | 1 |
| Wang, X | 1 |
| Gan, Y | 1 |
| Kuang, D | 1 |
| Yue, J | 1 |
| Ni, J | 1 |
| Zhao, X | 1 |
| Wang, G | 1 |
| Li, L | 1 |
| Sawamura, T | 1 |
| Renier, G | 1 |
| Zhao, B | 1 |
| Cai, J | 1 |
| Boulton, M | 1 |
| Devaraj, S | 1 |
| Venugopal, SK | 1 |
| Singh, U | 1 |
| Jialal, I | 1 |
| Venkatachalam, K | 1 |
| Mummidi, S | 1 |
| Cortez, DM | 1 |
| Prabhu, SD | 1 |
| Valente, AJ | 1 |
| Chandrasekar, B | 1 |
10 other studies available for pd 98059 and Hyperglycemia
| Article | Year |
|---|---|
Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Curcumin; Epi | 2019 |
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Sc | 2016 |
Potential Role of Hyperglycemia in Fetoplacental Endothelial Dysfunction in Gestational Diabetes Mellitus.
Topics: Adult; Case-Control Studies; Cell Movement; Cell Proliferation; Diabetes, Gestational; Diffusion Cha | 2016 |
Mechanism of action of the stimulatory effect of apigenin-6-C-(2''-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake.
Topics: Alloxan; Androstadienes; Animals; Biological Transport; Blood Glucose; Carbon Radioisotopes; Colchic | 2009 |
S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition.
Topics: Animals; Diabetic Nephropathies; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; F | 2012 |
Hyperglycemia suppresses cardiac stem cell homing to peri-infarcted myocardium via regulation of ERK1/2 and p38 MAPK activities.
Topics: Animals; Cell Movement; Cells, Cultured; Diabetes Mellitus, Experimental; Extracellular Signal-Regul | 2012 |
Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.
Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; | 2004 |
Expression of placenta growth factor is regulated by both VEGF and hyperglycaemia via VEGFR-2.
Topics: Animals; Blotting, Western; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavo | 2004 |
Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase c-{alpha} and -{beta}.
Topics: Cell Line; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Humans; Hyperglycemia; Imidazoles; Inter | 2005 |
Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts.
Topics: Animals; Cardiovascular Agents; Cell Culture Techniques; Cells, Cultured; Collagen; Enzyme Activatio | 2008 |