thiophenes has been researched along with Hyperglycemia in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 23 (74.19) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, HY; Gu, HB; Li, H; Shan, BS; Zhou, X | 1 |
| Ashworth, KE; Bush, ND; Halm, MK; Kemp, BE; Medak, KD; Shamshoum, H; Townsend, LK; Wright, DC | 1 |
| Gaikwad, AB; Sharma, N | 1 |
| Habu, M; Kurozumi, A; Okada, Y; Tanaka, Y | 1 |
| Takeishi, S; Takekoshi, S; Tsuboi, H | 1 |
| Chang, WT; Chen, ZC; Cheng, JT; Cheng, KC; Cheng, YZ; Li, Y | 1 |
| Ghosh, A; Heise, T; Plum-Mörschel, L; Polidori, D; Rothenberg, P; Sha, S | 1 |
| Hayashizaki, Y; Imamura, M; Kihara, R; Kobayashi, Y; Kurosaki, E; Li, Q; Noda, A; Sasamata, M; Shibasaki, M; Tahara, A; Takasu, T; Tomiyama, H; Yamajuku, D; Yokono, M | 2 |
| Condren, AB; Donahue, EP; Farmer, TD; Healey, EC; Kim, K; McCoy, GA; O'Brien, TP; Printz, RL; Shiota, M; Ueta, K | 1 |
| Dieu Van, NK; Han, P; Ji, L; Liu, Y; Meininger, G; Qiu, R; Vijapurkar, U; Yang, G | 1 |
| Arakawa, K; Hikida, K; Kakimoto, T; Kimata, H; Kuriyama, C; Lee, SP; Matsushita, Y; Nakayama, K; Qi, J; Saito, A; Shiotani, M; Taniuchi, N; Ueta, K; Watanabe, Y; Xu, JZ | 1 |
| Katakami, N; Matsuoka, TA; Shimomura, I; Shiraiwa, T; Takahara, M | 1 |
| Anvari, E; Walum, E; Welsh, N; Wikström, P | 1 |
| Hayashizaki, Y; Takakura, S; Takasu, T; Toyoshi, T | 1 |
| Bando, H; Horasawa, S; Kawasumi, K; Ohashi, K; Osame, K; Saito, S | 1 |
| Abiko, A; Atageldiyeva, K; Fujita, Y; Haneda, M; Honjo, J; Makino, Y; Mizumoto, K; Takeda, Y; Takiyama, Y; Yanagimachi, T | 1 |
| Kato, H; Nagai, Y; Ohta, A; Sada, Y; Tanaka, Y | 1 |
| Atsumi, T; Miyoshi, H; Nakamura, A; Takase, T; Yamamoto, C | 1 |
| Bajaj, M; Birnbaum, Y; Chen, H; Chen, Y; Nanhwan, MK; Qian, J; Ye, Y | 1 |
| Aleksunes, LM; Goedken, MJ; Klaassen, CD; Reisman, SA; Yeager, RL | 1 |
| Brecht, S; Crucitti, A; Nilsson, M; Wernicke, J; Yang, CR; Zhang, Q | 1 |
| Bae, MH; Chae, YN; Choi, HH; Choi, SH; Hur, Y; Kim, E; Kim, JG; Kim, MK; Lim, JI; Moon, HS; Park, CS; Park, YH; Shin, CY; Son, MH | 1 |
| Cassader, M; Gambino, R; Musso, G; Pagano, G | 1 |
| Kadokura, T; Krauwinkel, WJ; Smulders, RA; Veltkamp, SA | 1 |
| Arakawa, K; Conway, B; Conway, J; Demarest, K; Du, F; Kuriyama, C; Liang, Y; Liu, Y; Martin, T; Matsushita, Y; Polidori, D; Ueta, K; Ways, K; Xu, J | 1 |
| Cambray, AJ; D'Ambrosio, R; Higashi, H; Meno, JR; Winn, HR; Zhou, J | 1 |
| Bartlett, JB; Berg, S; Carey, F; Charles, AD; Convey, G; De Schoolmeester, J; Freeman, S; Loxham, SJ; Poucher, SM; Teague, J; Turnbull, AV; Walker, M | 1 |
| Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA | 1 |
| Hamada, Y; Hara, T; Hotta, N; Kamijo, M; Koh, N; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Wakao, T | 1 |
| Asensio Sánchez, VM | 1 |
2 review(s) available for thiophenes and Hyperglycemia
| Article | Year |
|---|---|
Duloxetine treatment and glycemic controls in patients with diagnoses other than diabetic peripheral neuropathic pain: a meta-analysis.
Topics: Antidepressive Agents; Anxiety Disorders; Blood Glucose; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Glycemic Index; Humans; Hyperglycemia; Male; Middle Aged; Mood Disorders; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2010 |
A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-transport (SGLT) inhibitors: systematic review and meta-analysis of randomized trials.
Topics: Benzhydryl Compounds; Blood Pressure; Body Mass Index; Canagliflozin; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Randomized Controlled Trials as Topic; Sodium-Glucose Transport Proteins; Thiophenes | 2012 |
5 trial(s) available for thiophenes and Hyperglycemia
| Article | Year |
|---|---|
Comparison of tofogliflozin 20 mg and ipragliflozin 50 mg used together with insulin glargine 300 U/mL using continuous glucose monitoring (CGM): A randomized crossover study.
Topics: Activities of Daily Living; Aged; Benzhydryl Compounds; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucosides; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Glargine; Japan; Male; Membrane Transport Modulators; Middle Aged; Monitoring, Ambulatory; Risk; ROC Curve; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2017 |
Validation of a novel method for determining the renal threshold for glucose excretion in untreated and canagliflozin-treated subjects with type 2 diabetes mellitus.
Topics: Blood Glucose; Body Mass Index; Canagliflozin; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Glucosides; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Kidney; Kidney Function Tests; Male; Membrane Transport Modulators; Middle Aged; Overweight; Postprandial Period; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
Canagliflozin in Asian patients with type 2 diabetes on metformin alone or metformin in combination with sulphonylurea.
Topics: Aged; Canagliflozin; China; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Malaysia; Male; Membrane Transport Modulators; Metformin; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Thiophenes; Vietnam | 2015 |
Effect of 24-week treatment with ipragliflozin on proinsulin/C-peptide ratio in Japanese patients with type 2 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Middle Aged; Proinsulin; Prospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2017 |
Effect of Ipragliflozin (ASP1941), a novel selective sodium-dependent glucose co-transporter 2 inhibitor, on urinary glucose excretion in healthy subjects.
Topics: Adult; Blood Glucose; Blood Pressure Determination; Body Mass Index; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Glucose; Glucosides; Glycosuria; Heart Rate; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Placebos; Sex Factors; Sodium-Glucose Transporter 2 Inhibitors; Symporters; Thiophenes; Young Adult | 2011 |
24 other study(ies) available for thiophenes and Hyperglycemia
| Article | Year |
|---|---|
AT2 Receptor Stimulation Inhibits Vascular Smooth Muscle Cell Senescence Induced by Angiotensin II and Hyperglycemia.
Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Cellular Senescence; Glucose; Hyperglycemia; Imidazoles; Male; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 2; Sirolimus; Sulfonamides; Superoxides; Thiophenes | 2022 |
AMPK β1 activation suppresses antipsychotic-induced hyperglycemia in mice.
Topics: AMP-Activated Protein Kinases; Animals; Antipsychotic Agents; Biphenyl Compounds; Blood Glucose; Female; Gene Deletion; Gene Expression Regulation, Enzymologic; Glucose Tolerance Test; Hyperglycemia; Mice; Olanzapine; Pyrones; Pyruvic Acid; Thiophenes | 2019 |
Effects of renal ischemia injury on brain in diabetic and non-diabetic rats: Role of angiotensin II type 2 receptor and angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Animals; Brain; Diabetes Mellitus, Experimental; Diminazene; Hyperglycemia; Imidazoles; Kidney Diseases; Kidney Tubules; Male; Malondialdehyde; Nitrites; Rats, Wistar; Receptor, Angiotensin, Type 2; Reperfusion Injury; Sulfonamides; Thiophenes | 2020 |
[Short-term Glucose Lowering Effects of Sodium-glucose Cotransporter 2 Inhibitors Confirmed by Flash Glucose Monitoring in Two Outpatients with Type 1 Diabetes].
Topics: Adult; Benzhydryl Compounds; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Female; Glucosides; Glycemic Control; Humans; Hyperglycemia; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2020 |
GW0742 activates peroxisome proliferator-activated receptor δ to reduce free radicals and alleviate cardiac hypertrophy induced by hyperglycemia in cultured H9c2 cells.
Topics: Animals; Blotting, Western; Calcium; Cardiomegaly; Cell Line; Free Radicals; Hyperglycemia; Rats; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes | 2018 |
Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Glucose Tolerance Test; Glucosides; Glycosuria; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Obesity; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Liver; Glomerular Filtration Rate; Glucose Intolerance; Glucosides; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Kidney; Liver; Male; Oxidative Stress; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Thiophenes | 2014 |
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Topics: Animals; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Eating; Glucagon; Glucokinase; Glucose; Glucose Clamp Technique; Glucosides; Hyperglycemia; Hyperinsulinism; Immunohistochemistry; Liver; Male; Obesity; Organ Size; Oxygen Consumption; Rats; Rats, Zucker; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2014 |
Analysis of the effect of canagliflozin on renal glucose reabsorption and progression of hyperglycemia in zucker diabetic Fatty rats.
Topics: Animals; Blood Glucose; Canagliflozin; Diabetes Mellitus, Experimental; Dogs; Glucose; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Kidney; Mice; Rats; Rats, Zucker; Sodium-Glucose Transporter 2; Thiophenes | 2014 |
Ameliorated pancreatic β cell dysfunction in type 2 diabetic patients treated with a sodium-glucose cotransporter 2 inhibitor ipragliflozin.
Topics: Adult; Algorithms; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Japan; Male; Middle Aged; Pilot Projects; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2015 |
The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice.
Topics: Animals; Diet, High-Fat; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucose Intolerance; High-Throughput Screening Assays; Humans; Hyperglycemia; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; NADPH Oxidases; Piperazines; Reactive Oxygen Species; Thiophenes | 2015 |
Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Progression; Glucosides; Hyperglycemia; Hypoglycemic Agents; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2016 |
[Efficacy of Ipragliflozin in Patients with Steroid-Induced Hyperglycemia during Cancer Chemotherapy].
Topics: Antiemetics; Blood Glucose; Chemoradiotherapy; Dexamethasone; Esophageal Neoplasms; Glucosides; Humans; Hyperglycemia; Male; Middle Aged; Neoplasm Staging; Thiophenes | 2016 |
Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice.
Topics: Animals; Body Weight; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experimental; Diet, Carbohydrate-Restricted; Energy Intake; Fatty Acid Synthases; Forkhead Box Protein O1; Gluconeogenesis; Glucose Tolerance Test; Glucosides; Glycogen; Hyperglycemia; Insulin Resistance; Kidney; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Obesity; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triglycerides; Up-Regulation | 2016 |
Amelioration of fatty liver index in patients with type 2 diabetes on ipragliflozin: an association with glucose-lowering effects.
Topics: Adiposity; Adult; Diabetes Mellitus, Type 2; Female; Glucosides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Japan; Lipotropic Agents; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Severity of Illness Index; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2017 |
Aleglitazar, a dual peroxisome proliferator-activated receptor-α and -γ agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia.
Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Cytochromes c; Cytoprotection; Dose-Response Relationship, Drug; Genotype; Hyperglycemia; Hypoglycemic Agents; Mice, Knockout; Myocytes, Cardiac; Oxazoles; Oxidative Stress; Phenotype; PPAR alpha; PPAR gamma; RNA Interference; Signal Transduction; Thiophenes; Time Factors; Transfection | 2017 |
Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose Intolerance; Glucose-6-Phosphatase; Hyperglycemia; Insulin; Liver; Liver Glycogen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Pancreas; Phosphoenolpyruvate Carboxykinase (GTP); Pyrazines; Pyruvate Kinase; RNA, Messenger; Thiones; Thiophenes; Urodynamics | 2010 |
PAM-1616, a selective peroxisome proliferator-activated receptor γ modulator with preserved anti-diabetic efficacy and reduced adverse effects.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cells, Cultured; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Phenylpropionates; PPAR alpha; PPAR delta; PPAR gamma; Rosiglitazone; Thiazolidinediones; Thiophenes; Water-Electrolyte Balance | 2011 |
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models.
Topics: Animals; Blood Glucose; Body Weight; Canagliflozin; Cells, Cultured; CHO Cells; Cricetinae; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucosides; Humans; Hyperglycemia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Rats; Rats, Zucker; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Weight Gain | 2012 |
Hippocampal injury and neurobehavioral deficits are improved by PD 81,723 following hyperglycemic cerebral ischemia.
Topics: Animals; Behavior, Animal; Cell Death; Dose-Response Relationship, Drug; Hippocampus; Hyperglycemia; Ischemic Attack, Transient; Male; Maze Learning; Neuroprotective Agents; Rats; Rats, Wistar; Reaction Time; Receptors, Purinergic P1; Thiophenes | 2003 |
An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.
Topics: Animals; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Tolerance Test; Glycogen Phosphorylase; Glycogen Synthase; Hepatocytes; Hyperglycemia; Inhibitory Concentration 50; Male; Obesity; Quinolones; Rats; Rats, Wistar; Rats, Zucker; Thiophenes | 2007 |
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans.
Topics: Acrylates; Adult; Angiotensin II; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Imidazoles; Kidney; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System; Thiophenes | 2000 |
Physiological and morphometric analyses of neuropathy in sucrose-fed OLETF rats.
Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dietary Sucrose; Enzyme Inhibitors; Erythrocytes; Humans; Hyperglycemia; Male; Neural Conduction; Platelet Aggregation; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Tetrazoles; Thiophenes | 2001 |
[Severe hyperglycemia caused by dorzolamide].
Topics: Antihypertensive Agents; Female; Humans; Hyperglycemia; Middle Aged; Severity of Illness Index; Sulfonamides; Thiophenes | 2001 |