Page last updated: 2024-10-25

chlorpromazine and Hyperglycemia

chlorpromazine has been researched along with Hyperglycemia in 29 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs."3.71Glucose intolerance with atypical antipsychotics. ( Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M, 2002)
"Chlorpromazine has very likely been responsible for a considerable increase in the prevalence of diabetes in hospitalized psychotics, while antidepressants can produce useful improvement of diabetic control, especially in brittle diabetics."1.26The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus. ( Zumoff, B, 1979)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199026 (89.66)18.7374
1990's0 (0.00)18.2507
2000's3 (10.34)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hedenmalm, K1
Hägg, S1
Ståhl, M1
Mortimer, O1
Spigset, O1
JILEK, L1
TROJAN, S1
LAITL, J1
ARNESON, GA1
RENKER, U1
TIWARI, NM1
BHIDE, MB1
SEN, SC1
BONACCORSI, A1
GARATTINI, S1
JORI, A2
Duncan, E1
Dunlop, BW1
Boshoven, W1
Woolson, SL1
Hamer, RM1
Phillips, LS1
Ichijo, M1
Ishihara, T1
Uchida, A1
Mori, K1
Dagli, AJ1
Bhattacharyya, J1
Das, KP1
Wannarka, GL1
Fletcher, HP1
Schnell, RC1
Zumoff, B1
Siddiqui, HH1
Malhotra, NK1
Bhatia, B1
Subramanian, R1
Vargas, I1
Kawada, ME1
Espósito Avella, M1
Dávila, L1
Bravo, C1
Carrara, MC1
Sato, T1
Mennear, JH4
Spratto, GR1
Miya, TS5
Hellman, B1
Lernmark, A1
Sehlin, J1
Täljedal, IB1
Proakis, AG1
Borowitz, JL1
Vapaatalo, H1
Karppanen, H1
Simánĕ, Z1
Likovská, M1
Thonnard-Neumann, E1
Stepanov, MN1
Ghafghazi, T2
Chalmers, RK1
Satoh, T1
Iwamoto, T1

Other Studies

29 other studies available for chlorpromazine and Hyperglycemia

ArticleYear
Glucose intolerance with atypical antipsychotics.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlor

2002
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
    Ceskoslovenska pediatrie, 1963, Volume: 18

    Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital

1963
[RESISTANCE OF THE BODY TO ANOXIA DURING THE COURSE OF ONTOGENESIS AND THE EFFECT OF CHLORPROMAZINE].
    Ceskoslovenska gynekologie, 1963, Volume: 28

    Topics: Aging; Body Temperature Regulation; Chlorpromazine; Hyperglycemia; Hypoxia; Metabolism; Pharmacology

1963
PHENOTHIAZINE DERIVATIVES AND GLUCOSE METABOLISM.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Animals; Bipolar Disorder; Carbohydrate Metabolism; Chlorpromazine; Diabetes Mellitus; Furunculosis;

1964
["ON CASE REPORTS ON SIDE-EFFECTS OF PHENOTHIAZINES"].
    Das Deutsche Gesundheitswesen, 1964, Feb-27, Volume: 19

    Topics: Carbohydrate Metabolism; Chlorpromazine; Diabetes Mellitus; Hyperglycemia; Insulin; Lipid Metabolism

1964
EFFECT OF CHLORPROMAZINE AND RELATED PHENOTHIAZINES ON EPINEPHRINE AND INSULIN INDUCED RESPONSE ON BLOOD SUGAR.
    Journal of experimental medical sciences, 1964, Volume: 8

    Topics: Animals; Blood Glucose; Chlorpromazine; Epinephrine; Hyperglycemia; Hypoglycemia; Insulin; Mice; Pha

1964
STUDIES ON THE HYPERGLYCAEMIA INDUCED BY CHLORPROMAZINE IN RATS.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Adrenal Medulla; Adrenalectomy; Chlorpromazine; Dibenzylchlorethamine; Glucose; Hyperglycemia; Injec

1964
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphe

2007
[Case of syndrome malin with a transient appearance of "multicore"].
    Rinsho shinkeigaku = Clinical neurology, 1983, Volume: 23, Issue:9

    Topics: Adult; Chlorpromazine; Coxsackievirus Infections; Dehydration; Enterovirus B, Human; Humans; Hypergl

1983
Severe hyperglycaemia following ingestion of chlorpromazine.
    The Journal of the Association of Physicians of India, 1984, Volume: 32, Issue:8

    Topics: Adult; Chlorpromazine; Female; Humans; Hyperglycemia; Suicide, Attempted

1984
Aggregation of insulin by chlorpromazine.
    Biochemical pharmacology, 2001, Nov-01, Volume: 62, Issue:9

    Topics: Animals; Antipsychotic Agents; Cattle; Chlorpromazine; Humans; Hyperglycemia; Insulin; Kinetics

2001
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine;

1979
The effects of psychotropic drugs and diuretics on blood glucose levels in diabetes mellitus.
    Comprehensive therapy, 1979, Volume: 5, Issue:4

    Topics: Blood Glucose; Chlorpromazine; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Psychotropic

1979
Factors affecting blood glucose and liver glycogen in chlorpromazine-treated mice subjected to simulated altitudes.
    The Indian journal of medical research, 1979, Volume: 70

    Topics: Altitude; Animals; Blood Glucose; Chlorpromazine; Hyperglycemia; Hypoxia; Injections, Intraperitonea

1979
Adrenal and liver participation in the rat's post-stress diabetic response.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Blood Proteins; Chlorpromazine; Diabetes Mell

1976
[Interaction of cadmium, diphenylhydantoin and chlorpromazine: their effect in the metabolism of carbohydrates in mice].
    Revista medica de Panama, 1985, Volume: 10, Issue:3

    Topics: Animals; Cadmium; Carbohydrate Metabolism; Chlorpromazine; Drug Interactions; Glucose Tolerance Test

1985
On the mechanism of the hyperglycaemic effect of chlorpromazine.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Animals; Blood Glucose; Chlorpromazine; Drug Synergism; Epinephrine; Ethanolamines; Hyperglycemia; N

1966
Glycemic effects of solanine in rats.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:4

    Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpromazine; Ergotamine; Female; Glucose Tolerance Test; G

1967
Failure of beta-adrenergic blocking agents to antagonize the hyperglycemic effect of epinephrine in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Animals; Chlorpromazine; Epinephrine; Hy

1971
The pancreatic -cell recognition of insulin secretagogues. V. Binding and stimulatory action of phlorizin.
    Molecular pharmacology, 1972, Volume: 8, Issue:6

    Topics: Animals; Antimycin A; Arginine; Carbon Isotopes; Chloromercuribenzoates; Chlorpromazine; Diabetes Me

1972
Phenothiazine-induced hyperglycemia: relation to CNS and adrenal effects.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Catecholamines; Cattle; Central Nervous Syste

1971
Chlorpromazine-induced glucose intolerance in the mouse.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:3

    Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental; Epinephrine; Fasting; Hyperglycemia; Liver

1970
Blood glucose, serum GOT and tissue catecholamines in rats after combined ethanol-tranquilizer administration.
    Agents and actions, 1970, Volume: 1, Issue:4

    Topics: Adrenal Glands; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Catecholamines; Chlormet

1970
A comparative study on the hyperglycemic effects of chlorpromazine and octoclothepine.
    Activitas nervosa superior, 1967, Volume: 9, Issue:4

    Topics: Adrenal Glands; Animals; Blood Glucose; Chlorpromazine; Hyperglycemia; Pituitary Gland; Rats

1967
Phenothiazines and diabetes in hospitalized women.
    The American journal of psychiatry, 1968, Volume: 124, Issue:7

    Topics: Age Factors; Chlorpromazine; Diabetes Mellitus; Female; Glycosuria; Gonads; Humans; Hyperglycemia; M

1968
[Change in the blood sugar level and peculiarities of prevention of surgical hyperglycemia in stomach resection under potentiated local anesthesia].
    Vestnik khirurgii imeni I. I. Grekova, 1968, Volume: 100, Issue:6

    Topics: Adult; Aged; Analgesics; Anesthesia, Local; Blood Glucose; Chlorpromazine; Drug Synergism; Female; G

1968
Chlorpromazine and epinephrine hyperglycemic mechanisms.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:10

    Topics: Adrenalectomy; Animals; Chlorpromazine; Depression, Chemical; Drug Synergism; Epinephrine; Glucose;

1968
Estradiol antagonism of chlorpromazine hyperglycemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:3

    Topics: Animals; Blood Glucose; Chlorpromazine; Diaphragm; Estradiol; Glucose; Hyperglycemia; Male; Rats

1968
Neurotropic drugs, electroshock and carbohydrate metabolism in the rat.
    Biochemical pharmacology, 1966, Volume: 15, Issue:3

    Topics: Adrenal Medulla; Animals; Blood Glucose; Chlordiazepoxide; Chlorpromazine; Electroconvulsive Therapy

1966