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azathioprine and Hyperglycemia

azathioprine has been researched along with Hyperglycemia in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Two hundred twenty-three recipients of first cadaveric kidney allografts were randomized to receive tacrolimus (TAC) + mycophenolate mofetil (MMF), TAC + azathioprine (AZA), or cyclosporine (Neoral; CsA) + MMF."9.10Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at three years. ( Ahsan, N; Alfrey, EJ; Corwin, C; Danovitch, G; Fitzsimmons, WE; Gonwa, T; Halloran, P; Hardy, M; Johnson, C; Leonhardt, M; Light, J; Metzger, R; Mulloy, L; Rocher, L; Scandling, J; Shield, C; Sorensen, J; Stegall, M; VanVeldhuisen, P; Wachs, M, 2003)
"Two hundred twenty-three recipients of first cadaveric kidney allografts were randomized to receive tacrolimus (TAC) + mycophenolate mofetil (MMF), TAC + azathioprine (AZA), or cyclosporine (Neoral; CsA) + MMF."5.10Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at three years. ( Ahsan, N; Alfrey, EJ; Corwin, C; Danovitch, G; Fitzsimmons, WE; Gonwa, T; Halloran, P; Hardy, M; Johnson, C; Leonhardt, M; Light, J; Metzger, R; Mulloy, L; Rocher, L; Scandling, J; Shield, C; Sorensen, J; Stegall, M; VanVeldhuisen, P; Wachs, M, 2003)
" Is the evidence now sufficient to support the routine use of regimens including CNIs in LN? Although CNIs appear to have similar efficacy to MMF-based regimens as induction therapy, and are comparable with azathioprine as maintenance treatment, CNI toxicities, such as new-onset hypertension, hyperglycaemia and nephrotoxicity, have been problematic."3.83Con: The use of calcineurin inhibitors in the treatment of lupus nephritis. ( Fernandez Nieto, M; Jayne, DR, 2016)
"Post-transplant diabetes mellitus is a significant risk factor for cardiovascular disease in solid organ transplantation."2.52Immunosuppression and Post-transplant Hyperglycemia. ( Montero, N; Pascual, J, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montero, N1
Pascual, J1
Fernandez Nieto, M1
Jayne, DR1
Gonwa, T1
Johnson, C1
Ahsan, N1
Alfrey, EJ1
Halloran, P1
Stegall, M1
Hardy, M1
Metzger, R1
Shield, C1
Rocher, L1
Scandling, J1
Sorensen, J1
Mulloy, L1
Light, J1
Corwin, C1
Danovitch, G1
Wachs, M1
VanVeldhuisen, P1
Leonhardt, M1
Fitzsimmons, WE1
RIFKIND, D1
MARCHIORO, TL1
WADDELL, WR1
STARZL, TE1
Paterson, AJ1
Lamey, PJ1
Lewis, MA1
Nolan, A1
Rademaker, M1
Walker, RE1
McCrindle, BW1
Coles, JG1
West, LJ1
Roth, D1
Milgrom, M1
Esquenazi, V1
Fuller, L1
Burke, G1
Miller, J1
Amiel, JA1
Toledo-Pereyra, LH1
Hill, CM1
Douglas, JF1
Rajkumar, KV1
McEvoy, J1
McGeown, MG1
Zimmermann, G1
Hell, E1
Anderson, RJ1
Schafer, LA1
Olin, DB1
Eickhoff, TC1
Gliedman, ML1
Gold, M1
Whittaker, J1
Rifkin, H1
Soberman, R1
Freed, S1
Tellis, V1
Veith, FJ1
Inou, T2
Ota, K2
Mori, S2
Reemtsma, K1
Giraldo, N1
Depp, DA1
Eichwald, EJ1
Kanazawa, Y1
Kuzuya, T1

Reviews

1 review available for azathioprine and Hyperglycemia

ArticleYear
Immunosuppression and Post-transplant Hyperglycemia.
    Current diabetes reviews, 2015, Volume: 11, Issue:3

    Topics: Adrenal Cortex Hormones; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Ever

2015

Trials

1 trial available for azathioprine and Hyperglycemia

ArticleYear
Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at three years.
    Transplantation, 2003, Jun-27, Volume: 75, Issue:12

    Topics: Acute Disease; Azathioprine; Cadaver; Creatinine; Cyclosporine; Drug Therapy, Combination; Florida;

2003

Other Studies

13 other studies available for azathioprine and Hyperglycemia

ArticleYear
Con: The use of calcineurin inhibitors in the treatment of lupus nephritis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016, Volume: 31, Issue:10

    Topics: Azathioprine; Calcineurin Inhibitors; Cyclophosphamide; Cyclosporine; Humans; Hyperglycemia; Hyperte

2016
INFECTIOUS DISEASES ASSOCIATED WITH RENAL HOMOTRANSPLANTATION.
    JAMA, 1964, Aug-10, Volume: 189

    Topics: Adolescent; Agammaglobulinemia; Agranulocytosis; Azathioprine; Bacteriophage Typing; Child; Diagnosi

1964
Pemphigus vulgaris precipitated by glibenclamide therapy.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1993, Volume: 22, Issue:2

    Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole

1993
Clinical outcomes associated with conversion to tacrolimus-based immunosuppression in pediatric cardiac transplantation.
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female;

1998
Posttransplant hyperglycemia. Increased incidence in cyclosporine-treated renal allograft recipients.
    Transplantation, 1989, Volume: 47, Issue:2

    Topics: Actuarial Analysis; Adult; Azathioprine; Cyclosporins; Diabetes Mellitus; Female; Graft Survival; Hu

1989
[Transplantation of pancreatic islets in dogs--a new method].
    Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1986, Volume: 19, Issue:4

    Topics: Animals; Azathioprine; Dogs; Hyperglycemia; Immunosuppression Therapy; Islets of Langerhans Transpla

1986
Glycosuria and hyperglycaemia after kidney transplantation.
    Lancet (London, England), 1974, Aug-31, Volume: 2, Issue:7879

    Topics: Acute Disease; Azathioprine; Glucose Tolerance Test; Glycosuria; Humans; Hydrocortisone; Hyperglycem

1974
[Transplantation and preservation by freezing of the pancreas in dogs].
    Langenbecks Archiv fur Chirurgie, 1971, Volume: 328, Issue:4

    Topics: Amylases; Animals; Azathioprine; Dogs; Female; Freezing; Glucose Tolerance Test; Graft Rejection; Gr

1971
Infectious risk factors in the immunosuppressed host.
    The American journal of medicine, 1973, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Agammaglobulinemia; Age Factors; Antilymphocyte Serum; Azathioprine; Child; Femal

1973
Clinical segmental pancreatic transplantation with ureter-pancreatic duct anastomosis for exocrine drainage.
    Surgery, 1973, Volume: 74, Issue:2

    Topics: Adult; Azathioprine; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Hyperglycemi

1973
Manifestations of rejection of pancreaticoduodenal allografts.
    Transplantation, 1968, Volume: 6, Issue:4

    Topics: Amylases; Animals; Azathioprine; Blood Glucose; Dogs; Duodenum; Histocompatibility; Hyperglycemia; I

1968
Islet cell transplantation.
    Annals of surgery, 1968, Volume: 168, Issue:3

    Topics: Animals; Azathioprine; Blood Glucose; Dogs; Female; Hyperglycemia; Male; Mercaptopurine; Pancreas; P

1968
Endocrine function of the pancreatic allograft.
    Endocrinology, 1968, Volume: 82, Issue:4

    Topics: Animals; Azathioprine; Blood Glucose; Dogs; Glucose Tolerance Test; Graft vs Host Disease; Hyperglyc

1968