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indomethacin and Hyperglycemia

indomethacin has been researched along with Hyperglycemia in 21 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
" The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i."1.32Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's4 (19.05)18.2507
2000's6 (28.57)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xian, T1
Gan, Y1
Lu, Y1
Wang, M1
Yuan, W1
Zhou, Y1
Chen, J1
Wang, K1
Xiong, S1
Huang, Q1
Zayachkivska, O1
Gzregotsky, M1
Ferentc, M1
Yaschenko, A1
Urbanovych, A1
Aljofan, M1
Ding, H1
Wong, YC1
Sim, MK1
Lee, KO1
Mori, A1
Suzuki, S1
Sakamoto, K1
Nakahara, T1
Ishii, K1
Stetinová, V1
Smetanová, L1
Grossmann, V1
Anzenbacher, P1
Matsumoto, T1
Wakabayashi, K1
Kobayashi, T1
Kamata, K1
Kafl, HE1
Elkashef, HA1
Schusdziarra, V2
Morenkova, SA1
Svetukhin, AM1
Begishev, RA1
Tkach, JR1
Taylor, PD1
Poston, L1
Wascher, TC1
Bachernegg, M1
Kickenweiz, A1
Stark, G1
Stark, U1
Toplak, H1
Graier, WF1
Grupp, LA1
Lau, V1
Harding, S1
Kondo, F1
Kondo, Y1
Makino, H1
Ogawa, N1
Kocsis, E1
Pacher, P1
Pósa, I1
Nieszner, E1
Pogátsa, G1
Koltai, MZ1
Rouiller, D1
Unger, RH1
Perico, N1
Benigni, A1
Gabanelli, M1
Piccinelli, A1
Ròg, M1
De Riva, C1
Remuzzi, G1
Hoeldtke, RD1
O'Dorisio, TM1
Boden, G1
Bratusch-Marrain, PR1
Vierhapper, H1
Komjati, M1
Waldhäusl, WK1
Amano, Y1
Takaori, S1

Reviews

1 review available for indomethacin and Hyperglycemia

ArticleYear
The role of somatostatin during the gastric phase of a meal.
    Hepato-gastroenterology, 1980, Volume: 27, Issue:3

    Topics: Atropine; Cimetidine; Digestion; Gastric Mucosa; Gastrins; Humans; Hydrogen-Ion Concentration; Hyper

1980

Trials

1 trial available for indomethacin and Hyperglycemia

ArticleYear
Treatment of autonomic neuropathy with a somatostatin analogue SMS-201-995.
    Lancet (London, England), 1986, Sep-13, Volume: 2, Issue:8507

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Caffeine; Chronic Disease; Female; H

1986

Other Studies

19 other studies available for indomethacin and Hyperglycemia

ArticleYear
Ameliorative effects of indomethacin at different concentrations on endothelial insulin resistance through two distinct pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug

2018
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 2

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione P

2008
High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells.
    Journal of cellular physiology, 2010, Volume: 222, Issue:3

    Topics: Acetophenones; Animals; Benzophenanthridines; Blotting, Western; Cells, Cultured; Cyclooxygenase 1;

2010
Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
    Biochemical pharmacology, 2011, Nov-01, Volume: 82, Issue:9

    Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cystinyl Aminopeptidase; Dietary Fats; Dietar

2011
Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats.
    European journal of pharmacology, 2011, Nov-01, Volume: 669, Issue:1-3

    Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus,

2011
In vitro and in vivo assessment of the antioxidant activity of melatonin and related indole derivatives.
    General physiology and biophysics, 2002, Volume: 21, Issue:2

    Topics: Alloxan; Animals; Antioxidants; Carboxylic Acids; Female; Hyaluronic Acid; Hyperglycemia; In Vitro T

2002
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
    Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen

2004
Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats.
    Pakistan journal of pharmaceutical sciences, 2006, Volume: 19, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; En

2006
[Effect of indomethacin on carbohydrate metabolism in generalized infection].
    Khirurgiia, 1984, Issue:7

    Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Indomethacin; Insulin;

1984
Indomethacin-induced hyperglycemia in psoriatic arthritis.
    Journal of the American Academy of Dermatology, 1982, Volume: 7, Issue:6

    Topics: Adult; Arthritis; Humans; Hyperglycemia; Indomethacin; Male; Psoriasis

1982
The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery.
    British journal of pharmacology, 1994, Volume: 113, Issue:3

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Hyperglycemia; In

1994
Involvement of the L-arginine-nitric oxide pathway in hyperglycaemia-induced coronary artery dysfunction of isolated guinea pig hearts.
    European journal of clinical investigation, 1996, Volume: 26, Issue:8

    Topics: Animals; Arginine; Blood Circulation; Coronary Vessels; Diabetes Mellitus, Type 1; Female; Glucose;

1996
The reduction in alcohol intake in rats by isoproterenol is attenuated by indomethacin but not enalapril: relationship to blood glucose levels.
    Psychopharmacology, 1998, Volume: 138, Issue:2

    Topics: Adrenergic beta-Agonists; Alcohol Drinking; Analysis of Variance; Angiotensin II; Angiotensin-Conver

1998
Delayed neuronal death in hippocampal CA1 pyramidal neurons after forebrain ischemia in hyperglycemic gerbils: amelioration by indomethacin.
    Brain research, 2000, Jan-17, Volume: 853, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Death; Gerbillinae; Hippocampus; H

2000
Hyperglycaemia alters the endothelium-dependent relaxation of canine coronary arteries.
    Acta physiologica Scandinavica, 2000, Volume: 169, Issue:3

    Topics: Acetylcholine; Animals; Blood Glucose; Coronary Vessels; Cyclooxygenase Inhibitors; Diabetes Mellitu

2000
Sympathectomy and prostaglandin deficiency do not prevent gastrogenic hyperglycaemia and hyperinsulinaemia.
    Acta endocrinologica, 1979, Volume: 92, Issue:4

    Topics: Animals; Blood Glucose; Dogs; Food; Gastrins; Glucagon; Hydrogen-Ion Concentration; Hydroxydopamines

1979
Atrial natriuretic peptide and prostacyclin synergistically mediate hyperfiltration and hyperperfusion of diabetic rats.
    Diabetes, 1992, Volume: 41, Issue:4

    Topics: Animals; Atrial Natriuretic Factor; Diabetes Mellitus, Experimental; Drug Synergism; Epoprostenol; G

1992
Acetyl-salicylic acid impairs insulin-mediated glucose utilization and reduces insulin clearance in healthy and non-insulin-dependent diabetic man.
    Diabetologia, 1985, Volume: 28, Issue:9

    Topics: Adult; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia;

1985
Effect of antiphlogistics on the level of blood glucose in the rat.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:4

    Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Blood Glucose; Fasting; Hexamethoniu

1968