indomethacin has been researched along with Hyperglycemia in 21 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i." | 1.32 | Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xian, T | 1 |
| Gan, Y | 1 |
| Lu, Y | 1 |
| Wang, M | 1 |
| Yuan, W | 1 |
| Zhou, Y | 1 |
| Chen, J | 1 |
| Wang, K | 1 |
| Xiong, S | 1 |
| Huang, Q | 1 |
| Zayachkivska, O | 1 |
| Gzregotsky, M | 1 |
| Ferentc, M | 1 |
| Yaschenko, A | 1 |
| Urbanovych, A | 1 |
| Aljofan, M | 1 |
| Ding, H | 1 |
| Wong, YC | 1 |
| Sim, MK | 1 |
| Lee, KO | 1 |
| Mori, A | 1 |
| Suzuki, S | 1 |
| Sakamoto, K | 1 |
| Nakahara, T | 1 |
| Ishii, K | 1 |
| Stetinová, V | 1 |
| Smetanová, L | 1 |
| Grossmann, V | 1 |
| Anzenbacher, P | 1 |
| Matsumoto, T | 1 |
| Wakabayashi, K | 1 |
| Kobayashi, T | 1 |
| Kamata, K | 1 |
| Kafl, HE | 1 |
| Elkashef, HA | 1 |
| Schusdziarra, V | 2 |
| Morenkova, SA | 1 |
| Svetukhin, AM | 1 |
| Begishev, RA | 1 |
| Tkach, JR | 1 |
| Taylor, PD | 1 |
| Poston, L | 1 |
| Wascher, TC | 1 |
| Bachernegg, M | 1 |
| Kickenweiz, A | 1 |
| Stark, G | 1 |
| Stark, U | 1 |
| Toplak, H | 1 |
| Graier, WF | 1 |
| Grupp, LA | 1 |
| Lau, V | 1 |
| Harding, S | 1 |
| Kondo, F | 1 |
| Kondo, Y | 1 |
| Makino, H | 1 |
| Ogawa, N | 1 |
| Kocsis, E | 1 |
| Pacher, P | 1 |
| Pósa, I | 1 |
| Nieszner, E | 1 |
| Pogátsa, G | 1 |
| Koltai, MZ | 1 |
| Rouiller, D | 1 |
| Unger, RH | 1 |
| Perico, N | 1 |
| Benigni, A | 1 |
| Gabanelli, M | 1 |
| Piccinelli, A | 1 |
| Ròg, M | 1 |
| De Riva, C | 1 |
| Remuzzi, G | 1 |
| Hoeldtke, RD | 1 |
| O'Dorisio, TM | 1 |
| Boden, G | 1 |
| Bratusch-Marrain, PR | 1 |
| Vierhapper, H | 1 |
| Komjati, M | 1 |
| Waldhäusl, WK | 1 |
| Amano, Y | 1 |
| Takaori, S | 1 |
1 review available for indomethacin and Hyperglycemia
| Article | Year |
|---|---|
The role of somatostatin during the gastric phase of a meal.
Topics: Atropine; Cimetidine; Digestion; Gastric Mucosa; Gastrins; Humans; Hydrogen-Ion Concentration; Hyper | 1980 |
1 trial available for indomethacin and Hyperglycemia
| Article | Year |
|---|---|
Treatment of autonomic neuropathy with a somatostatin analogue SMS-201-995.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Caffeine; Chronic Disease; Female; H | 1986 |
19 other studies available for indomethacin and Hyperglycemia
| Article | Year |
|---|---|
Ameliorative effects of indomethacin at different concentrations on endothelial insulin resistance through two distinct pathways.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug | 2018 |
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione P | 2008 |
High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells.
Topics: Acetophenones; Animals; Benzophenanthridines; Blotting, Western; Cells, Cultured; Cyclooxygenase 1; | 2010 |
Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cystinyl Aminopeptidase; Dietary Fats; Dietar | 2011 |
Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2011 |
In vitro and in vivo assessment of the antioxidant activity of melatonin and related indole derivatives.
Topics: Alloxan; Animals; Antioxidants; Carboxylic Acids; Female; Hyaluronic Acid; Hyperglycemia; In Vitro T | 2002 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen | 2004 |
Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; En | 2006 |
[Effect of indomethacin on carbohydrate metabolism in generalized infection].
Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Indomethacin; Insulin; | 1984 |
Indomethacin-induced hyperglycemia in psoriatic arthritis.
Topics: Adult; Arthritis; Humans; Hyperglycemia; Indomethacin; Male; Psoriasis | 1982 |
The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Hyperglycemia; In | 1994 |
Involvement of the L-arginine-nitric oxide pathway in hyperglycaemia-induced coronary artery dysfunction of isolated guinea pig hearts.
Topics: Animals; Arginine; Blood Circulation; Coronary Vessels; Diabetes Mellitus, Type 1; Female; Glucose; | 1996 |
The reduction in alcohol intake in rats by isoproterenol is attenuated by indomethacin but not enalapril: relationship to blood glucose levels.
Topics: Adrenergic beta-Agonists; Alcohol Drinking; Analysis of Variance; Angiotensin II; Angiotensin-Conver | 1998 |
Delayed neuronal death in hippocampal CA1 pyramidal neurons after forebrain ischemia in hyperglycemic gerbils: amelioration by indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Death; Gerbillinae; Hippocampus; H | 2000 |
Hyperglycaemia alters the endothelium-dependent relaxation of canine coronary arteries.
Topics: Acetylcholine; Animals; Blood Glucose; Coronary Vessels; Cyclooxygenase Inhibitors; Diabetes Mellitu | 2000 |
Sympathectomy and prostaglandin deficiency do not prevent gastrogenic hyperglycaemia and hyperinsulinaemia.
Topics: Animals; Blood Glucose; Dogs; Food; Gastrins; Glucagon; Hydrogen-Ion Concentration; Hydroxydopamines | 1979 |
Atrial natriuretic peptide and prostacyclin synergistically mediate hyperfiltration and hyperperfusion of diabetic rats.
Topics: Animals; Atrial Natriuretic Factor; Diabetes Mellitus, Experimental; Drug Synergism; Epoprostenol; G | 1992 |
Acetyl-salicylic acid impairs insulin-mediated glucose utilization and reduces insulin clearance in healthy and non-insulin-dependent diabetic man.
Topics: Adult; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; | 1985 |
Effect of antiphlogistics on the level of blood glucose in the rat.
Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Blood Glucose; Fasting; Hexamethoniu | 1968 |