Page last updated: 2024-12-07

2-amino-4-phenylbutyric acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-amino-4-phenylbutanoic acid: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID102530
CHEMBL ID203873
SCHEMBL ID130567
MeSH IDM0062800

Synonyms (57)

Synonym
dl-homophenylalanine, 98%
2-amino-4-phenylbutyric acid
AKOS000184444
2-amino-4-phenylbutanoic acid
CHEMBL203873 ,
FT-0691544
rac-2-amino-4-phenylbutanoic acid
bdbm50179729
1012-05-1
A800353
2-azanyl-4-phenyl-butanoic acid
2-amino-4-phenyl-butyric acid
dl-homophenylalanine
H1329
(-)-2-amino-4-phenylbutyric acid
ntl1ib8f3l ,
unii-ntl1ib8f3l
benzenebutanoic acid, alpha-amino-
FT-0641882
FT-0633244
FT-0627846
AM20060478
h-dl-hophe-oh
AB02512
AB00246
d,l-homophenylalanine
SCHEMBL130567
AKOS016038570
(2rs)-2-amino-4-phenylbutanoic acid
benzenebutanoic acid, .alpha.-amino-
dl-2-amino-4-phenylbutyric acid
lisinopril dihydrate impurity a [ep impurity]
homophenylalanine, dl-
benzenebutanoic acid, .alpha.-amino-, (+/-)-
homophenylalanine, (+/-)-
amino-.gamma.-phenylbutyric acid, dl-.alpha.
SY012187
SY012060
benzenebutanoic acid, .alpha.-amino-, (.+/-.)-
F8881-6103
STL481979
mfcd00063092
J-507879
h-dl-homophe-oh
lisinopril dihydrate imp. a (ep); lisinopril imp. a (ep); (2rs)-2-amino-4-phenylbutanoic acid; lisinopril dihydrate impurity a; lisinopril impurity a
(rs)-2-amino-4-phenyl-butyric acid
(r)-2-amino-4-phenyl-butyric acid
BCP25938
l-homophe-oh;(s)-2-amino-4-phenylbutyric acid
DTXSID80874100
AS-17599
BCP11593
Q27285054
CS-W017261
EN300-135009
SY034143
Z317025074
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Voltage-dependent calcium channel subunit alpha-2/delta-1Mus musculus (house mouse)Ki5.38520.10001.64665.4000AID261154
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID261154Displacement of [3H]L-leucine from alpha-2delta containing calcium channel in murine brain2006Bioorganic & medicinal chemistry letters, Mar-01, Volume: 16, Issue:5
Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (50)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's6 (12.00)18.2507
2000's23 (46.00)29.6817
2010's14 (28.00)24.3611
2020's7 (14.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.84 (24.57)
Research Supply Index4.08 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (3.45%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other56 (96.55%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]