Page last updated: 2024-11-06

prednisolone and Hyperglycemia

prednisolone has been researched along with Hyperglycemia in 63 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Prednisolone is a commonly used drug in cats and potential adverse effects include hyperglycaemia and diabetes mellitus."8.02Prednisolone-induced diabetes mellitus in the cat: a historical cohort. ( Boge, GS; Glanemann, B; Moberg, HL; Nerhagen, S, 2021)
" Cyclosporin A therapy quickly improved myasthenia gravis symptoms in all cases, which allowed a rapid reduction in the prednisolone dose and improvement of prednisolone-related hyperglycemia and hypertension."7.79Prednisolone-sparing effect of cyclosporin A therapy for very elderly patients with myasthenia gravis. ( Fujita, K; Kaneko, S; Kusaka, H; Morita, J; Nakamura, S; Nakano, S; Shinde, A, 2013)
"Prednisolone treatment aggravated fasting hyperglycemia and hyperinsulinemia caused by high-fat feeding, resulting in a higher homeostatic assessment model of insulin resistance."5.38Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance. ( Bloks, VW; Dokter, WH; Grefhorst, A; Groen, AK; Kuipers, F; Laskewitz, AJ; Reijngoud, DJ; Schreurs, M; van Dijk, TH; van Lierop, MJ, 2012)
"Eighteen subjects with rheumatoid arthritis who had not taken oral glucocorticoids for ≥6 months were studied before and after prednisolone 6 mg/day for 7 days to determine the acute effects of prednisolone."5.22Effect of acute and chronic glucocorticoid therapy on insulin sensitivity and postprandial vascular function. ( Burt, MG; Drake, SM; Heilbronn, LK; Jenkins, AB; Mangelsdorf, BL; Radhakutty, A; Samocha-Bonet, D; Smith, MD; Thompson, CH, 2016)
"We found that prednisolone treatment dose-dependently reduced C-peptide secretion following arginine stimulation on top of hyperglycemia (ASI-iAUCCP): -2."5.17Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance? ( Deacon, CF; Diamant, M; Heine, RJ; Holst, JJ; Karemaker, JM; Kwa, KA; Mari, A; Tushuizen, ME; van Genugten, RE; van Raalte, DH, 2013)
"Prednisolone is a commonly used drug in cats and potential adverse effects include hyperglycaemia and diabetes mellitus."4.02Prednisolone-induced diabetes mellitus in the cat: a historical cohort. ( Boge, GS; Glanemann, B; Moberg, HL; Nerhagen, S, 2021)
"To reveal how often patients with rheumatoid arthritis (RA) or any of other connective tissue diseases (CTDs) who take prednisolone (PSL) manifest postprandial hyperglycemia, and to evaluate the effects of divided daily dose administration of PSL, and of acarbose and nateglinide, on RA patients."3.80Early diagnosis and treatment of steroid-induced diabetes mellitus in patients with rheumatoid arthritis and other connective tissue diseases. ( Chino, Y; Goto, D; Hayashi, T; Ito, S; Kondo, Y; Matsumoto, I; Ogishima, H; Sugihara, M; Sumida, T, 2014)
" Cyclosporin A therapy quickly improved myasthenia gravis symptoms in all cases, which allowed a rapid reduction in the prednisolone dose and improvement of prednisolone-related hyperglycemia and hypertension."3.79Prednisolone-sparing effect of cyclosporin A therapy for very elderly patients with myasthenia gravis. ( Fujita, K; Kaneko, S; Kusaka, H; Morita, J; Nakamura, S; Nakano, S; Shinde, A, 2013)
"Prednisolone predominantly causes hyperglycemia in the afternoon and evening."3.77Continuous monitoring of circadian glycemic patterns in patients receiving prednisolone for COPD. ( Aguilar-Loza, NR; Burt, MG; Frith, P; Roberts, GW; Stranks, SN, 2011)
" She was treated with prednisolone, and < 1 year later she presented with marked hyperglycemia."3.70Successful treatment with plasmapheresis, cyclophosphamide, and cyclosporin A in type B syndrome of insulin resistance. Case report. ( Bremell, T; Eliasson, B; Eriksson, JW; Fowelin, J; Fredriksson, L; Yu, ZW, 1998)
" Here we characterise the safety of these agents in subpopulations and assess manageability of key adverse events (AEs)."3.30Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer. ( Bracarda, S; Chen, G; Chi, KN; de Bono, J; Garcia, J; Harris, A; Hinton, H; Massard, C; Matsubara, N; Olmos, D; Sandhu, S; Sane, R; Schenkel, F; Sternberg, CN; Sweeney, C, 2023)
"We performed a post-hoc analysis of a randomised, placebo-controlled, double blind, dose-response intervention study involving 32 healthy males (age: 22 ± 3 years; BMI 22."2.87The osteoblast: Linking glucocorticoid-induced osteoporosis and hyperglycaemia? A post-hoc analysis of a randomised clinical trial. ( Brands, M; de Jongh, RT; den Heijer, M; Heijboer, AC; Serlie, MJ; van Bommel, EJM; van Raalte, DH, 2018)
"Prednisolone is a major risk factor for hyperglycaemia and new-onset diabetes after transplantation."2.79Divided dosing reduces prednisolone-induced hyperglycaemia and glycaemic variability: a randomized trial after kidney transplantation. ( Cohney, SJ; Colman, PG; Fourlanos, S; Yates, CJ, 2014)
"Treatment of prednisolone-induced hyperglycaemia should be directed at the postprandial period."2.77Screening for diabetes in patients with inflammatory rheumatological disease administered long-term prednisolone: a cross-sectional study. ( Ahern, MJ; Burt, MG; Petersons, CJ; Smith, MD; Stranks, SN; Willenberg, VM, 2012)
"Hyperglycemia in children with acute lymphoblastic leukemia (ALL) has been well documented in the literature."2.69Clinical value of glycated hemoglobin and fructosamine in the long-term glycemic control of children with acute lymphoblastic leukemia. ( Ozbek, N; Yalçin, SS; Yetgin, S, 1998)
"A 66-year-old man with type 2 diabetes on hemodialysis treatment was admitted due to poor glycemic control."1.42Severe Insulin-resistant Diabetes due to Insulin Antibodies Associated with Eosinophilia. ( Nagao, M; Nakajima, Y; Oikawa, S; Sugihara, H; Takaya, M; Takemitsu, S; Uchigata, Y, 2015)
"Prednisolone treatment aggravated fasting hyperglycemia and hyperinsulinemia caused by high-fat feeding, resulting in a higher homeostatic assessment model of insulin resistance."1.38Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance. ( Bloks, VW; Dokter, WH; Grefhorst, A; Groen, AK; Kuipers, F; Laskewitz, AJ; Reijngoud, DJ; Schreurs, M; van Dijk, TH; van Lierop, MJ, 2012)
"She had been diagnosed with idiopathic thrombocytopenic purpura (ITP)."1.37Hyperglycemic hyperosmolar syndrome caused by steroid therapy in a patient with lupus nephritis. ( Choi, BS; Choi, SR; Chung, BH; Kang, SH; Kim, YS; Lee, JY; Park, CW; Park, HS; Sun, IO; Yang, CW, 2011)
"Previously it was shown in experimental arthritis that encapsulation of glucocorticoids (GC) as water-soluble phosphate esters in PEG-liposomes resulted in a strong improvement of the anti-inflammatory effect as compared to the free drug."1.37Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis. ( Beijnen, JH; Hofkens, W; Metselaar, JM; Nuijen, B; Storm, G; van den Hoven, JM; Wagenaar-Hilbers, JP; Wauben, MH, 2011)
"An 81-year-old man, with chronic renal failure due to chronic glomerulonephritis on maintenance hemodialysis (HD) for 4."1.34A case report of autoimmune pancreatitis accompanied with rapidly developing hyperglycemia and hypertension in a chronic hemodialysis patient. ( Shinoda, T; Wada, K; Yoshimoto, H, 2007)
"Thirteen patients with severe alcoholic hepatitis were treated with systemic steroids and TEN."1.32Combining steroids with enteral nutrition: a better therapeutic strategy for severe alcoholic hepatitis? Results of a pilot study. ( Alvarez, MA; Cabré, E; Gassull, MA; Lorenzo-Zúñiga, V; Montoliu, S; Planas, R, 2004)
" A long-term administration of antituberculous drugs affects hydrolysis and carbohydrate absorption in the small intestine."1.28[Hydrolysis and absorption of carbohydrates and correction of their disorders in patients with pulmonary tuberculosis]. ( Grishchuk, LA, 1990)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199019 (30.16)18.7374
1990's6 (9.52)18.2507
2000's8 (12.70)29.6817
2010's26 (41.27)24.3611
2020's4 (6.35)2.80

Authors

AuthorsStudies
Matsubara, N1
de Bono, J1
Sweeney, C1
Chi, KN1
Olmos, D1
Sandhu, S1
Massard, C1
Garcia, J1
Chen, G1
Harris, A1
Schenkel, F1
Sane, R1
Hinton, H1
Bracarda, S1
Sternberg, CN1
Chen, AX1
Radhakutty, A4
Zimmermann, A1
Stranks, SN5
Thompson, CH3
Burt, MG7
Hirota, Y1
Suwanai, H1
Yamauchi, T1
Kadowaki, T1
Nerhagen, S1
Moberg, HL1
Boge, GS1
Glanemann, B1
Nakagawa, R1
Takasawa, K1
Yeh, TW1
Imai, K1
Kashimada, K1
Morio, T1
van Bommel, EJM1
de Jongh, RT1
Brands, M1
Heijboer, AC1
den Heijer, M1
Serlie, MJ1
van Raalte, DH2
Wang, B1
Smyl, C1
Chen, CY1
Li, XY1
Huang, W1
Zhang, HM1
Pai, VJ1
Kang, JX1
Abbas, N1
Elhassan, M1
Kelly, P1
Yorke, R1
Mustafa, OG1
Whyte, MB1
Cansu, GB1
Cansu, DÜ1
Taşkıran, B1
Bilge, ŞY1
Bilgin, M1
Korkmaz, C1
Yates, CJ2
Fourlanos, S2
Colman, PG2
Cohney, SJ2
Ito, S2
Ogishima, H1
Kondo, Y1
Sugihara, M1
Hayashi, T1
Chino, Y1
Goto, D1
Matsumoto, I1
Sumida, T2
Sever, MS1
Brady, V1
Thosani, S1
Zhou, S1
Bassett, R1
Busaidy, NL1
Lavis, V1
Liu, XX1
Zhu, XM1
Miao, Q1
Ye, HY1
Zhang, ZY1
Li, YM1
Drake, SM3
Aguilar-Loza, NR2
Esterman, A1
Roberts, GW3
Takaya, M1
Nagao, M1
Takemitsu, S1
Nakajima, Y1
Sugihara, H1
Uchigata, Y1
Oikawa, S1
Mangelsdorf, BL2
Samocha-Bonet, D1
Jenkins, AB1
Heilbronn, LK1
Smith, MD2
Stranks, JL1
Zimmermann, AT1
Nakajima, A1
Doki, K1
Homma, M1
Sagae, T1
Saito, R1
Kohda, Y1
Sharma, A1
Pinto Pereira, LM1
Capildeo, K1
Charles, K1
Teelucksingh, S1
Kang, SH1
Lee, JY1
Park, HS1
Sun, IO1
Choi, SR1
Chung, BH1
Choi, BS1
Yang, CW1
Kim, YS1
Park, CW1
Frith, P1
van den Hoven, JM1
Hofkens, W1
Wauben, MH1
Wagenaar-Hilbers, JP1
Beijnen, JH1
Nuijen, B1
Metselaar, JM1
Storm, G1
Kappelgaard, P1
Hansen, KB1
Vilsbøll, T1
Knop, FK1
Larsen, M1
Willenberg, VM1
Petersons, CJ1
Ahern, MJ1
Laskewitz, AJ1
van Dijk, TH1
Grefhorst, A1
van Lierop, MJ1
Schreurs, M1
Bloks, VW1
Reijngoud, DJ1
Dokter, WH1
Kuipers, F1
Groen, AK1
Rohrmeier, C1
Koemm, N1
Babilas, P1
Prahs, P1
Strutz, J1
Buettner, R1
Kwa, KA1
van Genugten, RE1
Tushuizen, ME1
Holst, JJ1
Deacon, CF1
Karemaker, JM1
Heine, RJ1
Mari, A1
Diamant, M1
Nakamura, S1
Kaneko, S1
Shinde, A1
Morita, J1
Fujita, K1
Nakano, S1
Kusaka, H1
Mathew, JT1
Rao, M1
Job, V1
Ratnaswamy, S1
Jacob, CK1
ZHEREBTSOV, LA1
DUERR, F1
STAQUET, M1
YABO, R1
VIKTORA, J1
WOLFF, F1
Alvarez, MA1
Cabré, E1
Lorenzo-Zúñiga, V1
Montoliu, S1
Planas, R1
Gassull, MA1
Panthakalam, S1
Bhatnagar, D1
Klimiuk, P1
Koyama, R1
Nakanishi, K1
Kato, M1
Yamashita, S1
Kuwahara, H1
Katori, H1
Coll, AP1
Morganstein, D1
Jayne, D1
Soos, MA1
O'Rahilly, S1
Burke, J1
Uzu, T1
Harada, T1
Sakaguchi, M1
Kanasaki, M1
Isshiki, K1
Araki, S1
Sugiomoto, T1
Koya, D1
Haneda, M1
Kashiwagi, A1
Yamauchi, A1
Wada, K1
Shinoda, T1
Yoshimoto, H1
Tommasini, R1
Bloch, K1
Franceschini, J1
Longoni, A1
Mandelli, V1
Parenti, MA1
Passerini, N1
Valzelli, G1
Gulbenkian, A1
Grasso, AY1
Tabachnick, II1
Boyer, MH1
Takahara, S2
Kokado, Y1
Kameoka, H1
Takano, Y1
Jiang, H1
Moutabarrik, A1
Ishibashi, M2
Okuyama, A1
Sonoda, T1
Ochiai, T1
Fukao, K1
Takahashi, K1
Endo, T1
Yokoyama, I1
Uchida, K1
Ohshima, S1
Morozumi, K1
Paterson, AJ1
Lamey, PJ1
Lewis, MA1
Nolan, A1
Rademaker, M1
Yetgin, S1
Yalçin, SS1
Ozbek, N1
Eriksson, JW1
Bremell, T1
Eliasson, B1
Fowelin, J1
Fredriksson, L1
Yu, ZW1
Grishchuk, LA1
Kayanuma, K1
Matsumoto, Y1
Yomura, Y1
Uono, M1
Greenstone, MA1
Shaw, AB1
Middleton, DJ1
Watson, AD1
Muszbek, L1
Csaba, B1
Kovács, K1
Csizér, Z1
Hill, CM1
Douglas, JF1
Rajkumar, KV1
McEvoy, J1
McGeown, MG1
Zicha, L1
Bergner, D1
Christmann, A1
Zimmermann, G1
Hell, E1
Silberman, H1
Barker, CF1
Henderson, LW1
Gardner, L1
Murphy, JJ1
Khudoleeva, AB1
Lewis, GP1
Jick, H1
Slone, D1
Shapiro, S1
Kurzweg, W1
Umlauft, KD1
Rotermund, L1
Dwaronat, A1
Khan, A1
Adachi, M1
Hill, JM1
Ulmer, WT1
Nicolas, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Neutral Protamine Hagedorn (NPH) Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia[NCT03511521]Phase 43 participants (Actual)Interventional2018-03-27Terminated (stopped due to Unable to recruit sufficient number of patients)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Glycemic Control

mean of 4 glucose levels per day (premeal and bedtime) for each group for first 3 days after intervention (NCT03511521)
Timeframe: 3 days

Interventionmg/dL (Mean)
NPH Insulin284.3
Basal/Bolus Insulin184.3

Percentage of Glucose Values Within the Hypoglycemic Range

Percentage of the glucose values (premeal and bedtime for 3 days) less than 70 mg/dL and 54 mg/dL (NCT03511521)
Timeframe: 3 days

InterventionPercentage of glucose values < 70 mg/dL (Mean)
NPH Insulin0
Basal/Bolus Insulin0

Percentage of Glucose Values Within Therapeutic Range

Percentage of the glucose values (premeal and bedtime for 3 days) within the therapeutic target of 80 - 180 mg/dL (NCT03511521)
Timeframe: 3 days

Interventionpercentage of glucose values in range (Mean)
NPH Insulin4.2
Basal/Bolus Insulin50

Reviews

2 reviews available for prednisolone and Hyperglycemia

ArticleYear
MANAGEMENT OF ENDOCRINE DISEASE: Critical review of the evidence underlying management of glucocorticoid-induced hyperglycaemia
    European journal of endocrinology, 2018, 10-01, Volume: 179, Issue:4

    Topics: Blood Glucose; Evidence-Based Medicine; Glucocorticoids; Glycated Hemoglobin; Humans; Hyperglycemia;

2018
Hyperglycemia induced by glucocorticoids in nondiabetic patients: a meta-analysis.
    Annals of nutrition & metabolism, 2014, Volume: 65, Issue:4

    Topics: Databases, Factual; Diabetes Mellitus, Type 2; Glucocorticoids; Humans; Hyperglycemia; Incidence; Pr

2014

Trials

12 trials available for prednisolone and Hyperglycemia

ArticleYear
Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer.
    Clinical genitourinary cancer, 2023, Volume: 21, Issue:2

    Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Exanthema; Humans; Hyperglycemi

2023
The osteoblast: Linking glucocorticoid-induced osteoporosis and hyperglycaemia? A post-hoc analysis of a randomised clinical trial.
    Bone, 2018, Volume: 112

    Topics: Adult; Blood Glucose; Dose-Response Relationship, Drug; Double-Blind Method; Glucocorticoids; Humans

2018
Screening for new-onset diabetes after kidney transplantation: limitations of fasting glucose and advantages of afternoon glucose and glycated hemoglobin.
    Transplantation, 2013, Oct-27, Volume: 96, Issue:8

    Topics: Adult; Blood Glucose; Circadian Rhythm; Cross-Sectional Studies; Fasting; Female; Glucocorticoids; G

2013
Divided dosing reduces prednisolone-induced hyperglycaemia and glycaemic variability: a randomized trial after kidney transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:3

    Topics: Adult; Blood Glucose; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Hyperglycemi

2014
Effect of acute and chronic glucocorticoid therapy on insulin sensitivity and postprandial vascular function.
    Clinical endocrinology, 2016, Volume: 84, Issue:4

    Topics: Aged; Arthritis, Rheumatoid; Blood Glucose; Cross-Sectional Studies; Drug Administration Schedule; F

2016
Treatment of prednisolone-induced hyperglycaemia in hospitalized patients: Insights from a randomized, controlled study.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:4

    Topics: Aged; Blood Glucose; Drug Administration Schedule; Female; Hospitalization; Humans; Hyperglycemia; H

2017
Screening for diabetes in patients with inflammatory rheumatological disease administered long-term prednisolone: a cross-sectional study.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; D

2012
Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Anthropometry; Arginine; Blood Glucose; Dose-Response Relationship, Drug; Double-

2013
Monitoring of FK 506 blood levels in kidney transplant recipients.
    Transplantation proceedings, 1994, Volume: 26, Issue:4

    Topics: Drug Monitoring; Family; Graft Rejection; Humans; Hyperglycemia; Kidney Transplantation; Metabolic C

1994
Japanese multicenter studies of FK 506 in renal transplantation. Japanese FK 506 Study Group.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Amylases; Cholesterol; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Graft Rejection;

1995
Clinical value of glycated hemoglobin and fructosamine in the long-term glycemic control of children with acute lymphoblastic leukemia.
    Acta paediatrica Japonica : Overseas edition, 1998, Volume: 40, Issue:1

    Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Female; Fructosamine; Glucocorticoids; Glycated

1998
Alternate day corticosteroid causes alternate day hyperglycaemia.
    Postgraduate medical journal, 1987, Volume: 63, Issue:743

    Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Drug Administration Schedule; Female; Hum

1987

Other Studies

49 other studies available for prednisolone and Hyperglycemia

ArticleYear
Clinical determinants of insulin requirements during treatment of prednisolone-induced hyperglycaemia.
    Diabetes research and clinical practice, 2023, Volume: 197

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypergly

2023
Clinical Features of Type B Insulin Resistance in Japanese Patients: Case Report and Survey-Based Case Series Study.
    Journal of diabetes research, 2020, Volume: 2020

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Blood Glucose; Female; Humans; Hype

2020
Prednisolone-induced diabetes mellitus in the cat: a historical cohort.
    Journal of feline medicine and surgery, 2021, Volume: 23, Issue:2

    Topics: Animals; Cat Diseases; Cats; Diabetes Mellitus; Hyperglycemia; Prednisolone; Risk Factors

2021
Type 1 diabetes mellitus associated with activated phosphatidylinositol 3-kinase delta syndrome, type 2.
    Journal of diabetes, 2018, Volume: 10, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Class I Phosphatidylinositol 3-Kinases; Diabetes Mellitus, Type 1;

2018
Suppression of Postprandial Blood Glucose Fluctuations by a Low-Carbohydrate, High-Protein, and High-Omega-3 Diet via Inhibition of Gluconeogenesis.
    International journal of molecular sciences, 2018, Jun-21, Volume: 19, Issue:7

    Topics: Alanine; Alanine Transaminase; Animals; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Experimen

2018
Greater illness severity characterises steroid diabetes following acute hospitalisation.
    Clinical medicine (London, England), 2019, Volume: 19, Issue:1

    Topics: Blood Glucose; Diabetes Mellitus; Female; Glucocorticoids; Hospitalization; Humans; Hyperglycemia; I

2019
What is the optimal time for measuring glucose concentration to detect steroid-induced hyperglycemia in patients with rheumatic diseases?
    Clinical biochemistry, 2019, Volume: 67

    Topics: Adrenal Cortex Hormones; Adult; Blood Glucose; Female; Humans; Hyperglycemia; Male; Middle Aged; Pre

2019
Early diagnosis and treatment of steroid-induced diabetes mellitus in patients with rheumatoid arthritis and other connective tissue diseases.
    Modern rheumatology, 2014, Volume: 24, Issue:1

    Topics: Acarbose; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Glucose; Connective Tissue

2014
Transplantation-steroid-impaired glucose metabolism: a hope for improvement?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:3

    Topics: Blood Glucose; Carbohydrate Metabolism; Glucose; Humans; Hyperglycemia; Immunosuppressive Agents; Ki

2014
Safe and effective dosing of basal-bolus insulin in patients receiving high-dose steroids for hyper-cyclophosphamide, doxorubicin, vincristine, and dexamethasone chemotherapy.
    Diabetes technology & therapeutics, 2014, Volume: 16, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Can

2014
Efficacy of a basal bolus insulin protocol to treat prednisolone-induced hyperglycaemia in hospitalised patients.
    Internal medicine journal, 2015, Volume: 45, Issue:3

    Topics: Aged; Aged, 80 and over; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female;

2015
Severe Insulin-resistant Diabetes due to Insulin Antibodies Associated with Eosinophilia.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:18

    Topics: Aged; Antibodies; Blood Glucose; Diabetes Mellitus, Type 2; Eosinophilia; Glucocorticoids; Humans; H

2015
[Investigation of glucocorticoid-induced side effects in patients with autoimmune diseases].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2009, Volume: 129, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Appetite; Autoimmune Diseases; Candidiasis, Oral; Dose-Response Rela

2009
Steroid-induced iatrogenic disease after treating for pseudothrombocytopenia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:1

    Topics: Bone Diseases, Metabolic; Diabetes Mellitus; Diagnostic Errors; Glucocorticoids; Humans; Hyperglycem

2011
Hyperglycemic hyperosmolar syndrome caused by steroid therapy in a patient with lupus nephritis.
    Journal of Korean medical science, 2011, Volume: 26, Issue:3

    Topics: Edema; Epilepsies, Myoclonic; Female; Humans; Hyperglycemia; Immunosuppression Therapy; Insulin; Lup

2011
Continuous monitoring of circadian glycemic patterns in patients receiving prednisolone for COPD.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Blood Glucose; Blood Glucose Self-Monitoring; Cro

2011
Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis.
    International journal of pharmaceutics, 2011, Sep-20, Volume: 416, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Body Weight; Budesonide; Dexamethasone;

2011
Electroretinography in healthy subjects in relation to systemic glucocorticoid intake.
    Documenta ophthalmologica. Advances in ophthalmology, 2012, Volume: 124, Issue:1

    Topics: Adult; Electroretinography; Follow-Up Studies; Glucocorticoids; Glucose Tolerance Test; Humans; Hype

2012
Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance.
    Endocrinology, 2012, Volume: 153, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Dietary Fats; Hyperglycemia; Insulin Resistance; M

2012
Sudden sensorineural hearing loss: systemic steroid therapy and the risk of glucocorticoid-induced hyperglycemia.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:4

    Topics: Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-

2013
Prednisolone-sparing effect of cyclosporin A therapy for very elderly patients with myasthenia gravis.
    Neuromuscular disorders : NMD, 2013, Volume: 23, Issue:2

    Topics: Aged, 80 and over; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female

2013
Post-transplant hyperglycaemia: a study of risk factors.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:1

    Topics: Adult; Analysis of Variance; Blood Glucose; Body Mass Index; Cyclosporine; Female; Glucose Tolerance

2003
[COMPLICATIONS DURING PREDNISOLONE THERAPY OF CHRONIC HEPATITIS AND LIVER CIRRHOSIS].
    Terapevticheskii arkhiv, 1963, Volume: 35

    Topics: Adolescent; Adrenocortical Hyperfunction; Cardiovascular System; Dyspepsia; Geriatrics; Glycosuria;

1963
[PATHOPHYSIOLOGY AND THERAPY OF DIABETIC COMA].
    Deutsche medizinische Wochenschrift (1946), 1964, Nov-06, Volume: 89

    Topics: Acidosis; Bicarbonates; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Fructose; Humans; H

1964
AN ADRENERGIC MECHANISM FOR HYPERGLYCEMIA INDUCED BY DIAZOXIDE.
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic Agents; Antihypertensive Agents; Cyanides; Diazoxide; Dogs

1965
Combining steroids with enteral nutrition: a better therapeutic strategy for severe alcoholic hepatitis? Results of a pilot study.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:12

    Topics: Adult; Alcohol Drinking; Combined Modality Therapy; Communicable Diseases; Drug Administration Sched

2004
The prevalence and management of hyperglycaemia in patients with rheumatoid arthritis on corticosteroid therapy.
    Scottish medical journal, 2004, Volume: 49, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Diabetes Mellitus; F

2004
Hypoglycemia and hyperglycemia due to insulin antibodies against therapeutic human insulin: treatment with double filtration plasmapheresis and prednisolone.
    The American journal of the medical sciences, 2005, Volume: 329, Issue:5

    Topics: Adult; Aged; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus; Female; Humans; Hyperglyce

2005
Successful treatment of Type B insulin resistance in a patient with otherwise quiescent systemic lupus erythematosus.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:6

    Topics: Adult; Diabetes Complications; Female; Glucocorticoids; Humans; Hyperglycemia; Hypoglycemic Agents;

2005
Glucocorticoid-induced diabetes mellitus: prevalence and risk factors in primary renal diseases.
    Nephron. Clinical practice, 2007, Volume: 105, Issue:2

    Topics: Adult; Age Factors; Blood Glucose; Body Mass Index; Circadian Rhythm; Diabetes Mellitus; Female; Glu

2007
A case report of autoimmune pancreatitis accompanied with rapidly developing hyperglycemia and hypertension in a chronic hemodialysis patient.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2007, Volume: 11, Issue:2

    Topics: Aged, 80 and over; Autoimmune Diseases; Cholangiopancreatography, Endoscopic Retrograde; Diabetes Co

2007
Pharmacological activity of pregna-1,4-diene-3,20-dione-11 (beta),17(alpha)-21-triol-21-stearoylglycolate.
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Capillary Resistance; Diuresis; Dogs; Edema; Gluco

1966
The effect of altered carbohydrate metabolism in pertussis-sensitized mice on anaphylaxis.
    Biochemical pharmacology, 1967, Volume: 16, Issue:5

    Topics: Alloxan; Anaphylaxis; Animals; Blood Glucose; Body Weight; Diazoxide; Eating; Epinephrine; Female; G

1967
Hyperosmolar anacidotic coma in association with glucocorticoid therapy.
    JAMA, 1967, Dec-11, Volume: 202, Issue:11

    Topics: Acidosis; Adult; Aged; Coma; Dehydration; Female; Humans; Hyperglycemia; Male; Middle Aged; Osmosis;

1967
Pemphigus vulgaris precipitated by glibenclamide therapy.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1993, Volume: 22, Issue:2

    Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole

1993
Successful treatment with plasmapheresis, cyclophosphamide, and cyclosporin A in type B syndrome of insulin resistance. Case report.
    Diabetes care, 1998, Volume: 21, Issue:8

    Topics: Adipocytes; Animals; Autoantibodies; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Fema

1998
[Hydrolysis and absorption of carbohydrates and correction of their disorders in patients with pulmonary tuberculosis].
    Problemy tuberkuleza, 1990, Issue:3

    Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Folic Acid; Hexoses; Hu

1990
[A case of epilepsia partialis continua associated with nonketotic hyperglycemia due to steroid-induced diabetes mellitus].
    Rinsho shinkeigaku = Clinical neurology, 1987, Volume: 27, Issue:1

    Topics: Diabetes Mellitus, Type 2; Epilepsies, Partial; Humans; Hyperglycemia; Male; Middle Aged; Prednisolo

1987
Glucose intolerance in cats given short-term therapies of prednisolone and megestrol acetate.
    American journal of veterinary research, 1985, Volume: 46, Issue:12

    Topics: Animals; Blood Glucose; Cat Diseases; Cats; Female; Hyperglycemia; Male; Megestrol; Megestrol Acetat

1985
The effect of Bordetella pertussis vaccine on epinephrine induced hyperglycemia in rats.
    Acta allergologica, 1971, Volume: 26, Issue:6

    Topics: Animals; Blood Glucose; Drug Interactions; Epinephrine; Histamine Release; Hyperglycemia; Hypoglycem

1971
Glycosuria and hyperglycaemia after kidney transplantation.
    Lancet (London, England), 1974, Aug-31, Volume: 2, Issue:7879

    Topics: Acute Disease; Azathioprine; Glucose Tolerance Test; Glycosuria; Humans; Hydrocortisone; Hyperglycem

1974
[Glucocorticoids and glucose metabolism. 2. Studies on the influence of metopirone on glucose tolerance with and without additional application of adrenocorticotropic hormone and prenisolone].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Hu

1966
[Transplantation and preservation by freezing of the pancreas in dogs].
    Langenbecks Archiv fur Chirurgie, 1971, Volume: 328, Issue:4

    Topics: Amylases; Animals; Azathioprine; Dogs; Female; Freezing; Glucose Tolerance Test; Graft Rejection; Gr

1971
Functional ureteral obstruction and massive diuresis following renal homotransplantation.
    The Journal of urology, 1972, Volume: 108, Issue:6

    Topics: Adolescent; Diuresis; Electrolytes; Glycosuria; Humans; Hyperglycemia; Kidney Function Tests; Kidney

1972
[Nature of complications in patients with pemphigus in long-term treatment with corticosteroid hormones].
    Sovetskaia meditsina, 1974, Volume: 37, Issue:3

    Topics: Adult; Aged; Cushing Syndrome; Female; Humans; Hyperglycemia; Male; Middle Aged; Osteoporosis; Pemph

1974
The role of genetic factors and serum protein binding in determining drug response as revealed by comprehensive drug surveillance.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: ABO Blood-Group System; Blood Proteins; Computers; Contraceptives, Oral; Female; Genetics, Medical;

1971
[Clinical and laboratory diagnostic studies on the use of prednisolone in experimental carbohydrate poisoning in cattle].
    Archiv fur experimentelle Veterinarmedizin, 1969, Volume: 23, Issue:4

    Topics: Animals; Blood Glucose; Carbohydrates; Cattle; Cattle Diseases; Glycosuria; Hyperglycemia; Poisoning

1969
Potentiation of diabetogenic effect of L-asparaginase by prednisolone.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1970, Volume: 2, Issue:5

    Topics: Animals; Asparaginase; Blood Glucose; Diabetes Mellitus; Drug Synergism; Glycosuria; Hyperglycemia;

1970
[Long-term treatment of chronic obstructive bronchitis with corticosteroids].
    Deutsche medizinische Wochenschrift (1946), 1966, Oct-21, Volume: 91, Issue:42

    Topics: Adrenal Cortex Hormones; Adult; Aged; Bronchitis; Follow-Up Studies; Humans; Hyperglycemia; Middle A

1966