metronidazole has been researched along with Hyperglycemia in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Tucker, TR | 1 |
Knitter, CA | 1 |
Khoury, DM | 1 |
Eshghi, S | 1 |
Tran, S | 1 |
Sharrock, AV | 1 |
Wiles, TJ | 1 |
Ackerley, DF | 1 |
Mumm, JS | 1 |
Parsons, MJ | 1 |
Rocker, A | 1 |
Howell, J | 1 |
Voithofer, G | 1 |
Clark, JK | 1 |
Rao, DD | 1 |
Desai, A | 1 |
Kulkarni, RD | 1 |
Gopalkrishnan, K | 1 |
Rao, CB | 1 |
3 other studies available for metronidazole and Hyperglycemia
Article | Year |
---|---|
An inducible model of chronic hyperglycemia.
Topics: Animals; Animals, Genetically Modified; Diabetes Mellitus; Hyperglycemia; Metronidazole; Nitroreduct | 2023 |
Acute effects of hyperglycemia on the peripheral nervous system in zebrafish ( Danio rerio) following nitroreductase-mediated β-cell ablation.
Topics: Animals; Animals, Genetically Modified; Basic Helix-Loop-Helix Transcription Factors; Behavior, Anim | 2019 |
Comparison of maxillofacial space infection in diabetic and nondiabetic patients.
Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Case-Control Studi | 2010 |