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metronidazole and Hyperglycemia

metronidazole has been researched along with Hyperglycemia in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Tucker, TR1
Knitter, CA1
Khoury, DM1
Eshghi, S1
Tran, S1
Sharrock, AV1
Wiles, TJ1
Ackerley, DF1
Mumm, JS1
Parsons, MJ1
Rocker, A1
Howell, J1
Voithofer, G1
Clark, JK1
Rao, DD1
Desai, A1
Kulkarni, RD1
Gopalkrishnan, K1
Rao, CB1

Other Studies

3 other studies available for metronidazole and Hyperglycemia

ArticleYear
An inducible model of chronic hyperglycemia.
    Disease models & mechanisms, 2023, 08-01, Volume: 16, Issue:8

    Topics: Animals; Animals, Genetically Modified; Diabetes Mellitus; Hyperglycemia; Metronidazole; Nitroreduct

2023
Acute effects of hyperglycemia on the peripheral nervous system in zebrafish ( Danio rerio) following nitroreductase-mediated β-cell ablation.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2019, 04-01, Volume: 316, Issue:4

    Topics: Animals; Animals, Genetically Modified; Basic Helix-Loop-Helix Transcription Factors; Behavior, Anim

2019
Comparison of maxillofacial space infection in diabetic and nondiabetic patients.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 110, Issue:4

    Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Case-Control Studi

2010