1-methyl-3-isobutylxanthine has been researched along with Hyperglycemia in 6 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When mannoheptulose was introduced 15 min after starting perfusion with 27 mM glucose, inhibition was apparent in non-diabetic rats, but not in STZ." | 1.27 | B cell insensitivity in a rat model of non-insulin-dependent diabetes. Evidence for a rapidly reversible effect of previous hyperglycemia. ( Grill, V; Ostenson, CG; Westberg, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balbo, SL | 1 |
| Ribeiro, RA | 1 |
| Mendes, MC | 1 |
| Lubaczeuski, C | 1 |
| Maller, AC | 1 |
| Carneiro, EM | 1 |
| Bonfleur, ML | 1 |
| Wogensen, L | 1 |
| Ma, YH | 1 |
| Grodsky, GM | 1 |
| Robertson, RP | 1 |
| Burton, F | 1 |
| Sutcliffe, JG | 1 |
| Sarvetnick, N | 1 |
| Khan, A | 1 |
| Ostenson, CG | 2 |
| Berggren, PO | 1 |
| Efendic, S | 1 |
| Sako, Y | 1 |
| Grill, VE | 1 |
| Grill, V | 2 |
| Rundfeldt, M | 1 |
| Westberg, M | 1 |
6 other studies available for 1-methyl-3-isobutylxanthine and Hyperglycemia
| Article | Year |
|---|---|
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Functional effects of transgenic expression of cholera toxin in pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cholera Toxin; Colforsin; Cyclic AMP; Female; G | 1993 |
Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Glucose; Hyperglycemia; Insulin; | 1992 |
A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Dexamethasone | 1990 |
Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozocin-diabetic and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; | 1986 |
B cell insensitivity in a rat model of non-insulin-dependent diabetes. Evidence for a rapidly reversible effect of previous hyperglycemia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; B-Lymphocytes; Diabetes Mellitus, Experimental; Diabetes Melli | 1987 |