glucagon has been researched along with Hyperglycemia in 931 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 422 (45.33) | 18.7374 |
| 1990's | 133 (14.29) | 18.2507 |
| 2000's | 128 (13.75) | 29.6817 |
| 2010's | 202 (21.70) | 24.3611 |
| 2020's | 46 (4.94) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Cui, C; Cui, Y; Guo, X; He, Q; Hou, X; Hu, H; Li, W; Liang, K; Liu, F; Qin, J; Song, J; Sun, Y; Sun, Z; Wang, C; Wang, J; Wang, L; Yan, F; Yang, M; Zang, N; Zhao, R | 1 |
| Asadi, F; Dhanvantari, S | 1 |
| Aas Holm, L; Ängquist, L; Christiansen, M; de Retana Alzola, IF; Fonvig, CE; Frithioff-Bøjsøe, C; Hansen, T; Hartmann, B; Holm, JC; Holst, JJ; Jonsson, AE; Lund, MAV; Pedersen, O; Stinson, SE; Sørensen, TIA | 1 |
| Adebiyi, A; Kanthakumar, P; Kumar, R; Peixoto-Neves, D; Soni, H | 1 |
| Hahn, MK; McKie, GL; Medak, KD; Shamshoum, H; Wright, DC | 1 |
| Dan, K; Fushimi, Y; Iwamoto, H; Iwamoto, Y; Kaku, K; Kaneto, H; Katakura, Y; Kimura, T; Kubo, M; Mune, T; Nakanishi, S; Nakao, E; Sanada, J; Shimoda, M; Sugisaki, T; Takahashi, K; Tatsumi, F; Wamata, R | 1 |
| Chen, X; Gao, J; Hu, C; Huang, K; Hui, X; Jin, M; Sun, X; Wang, T; Wu, C; Yang, Y; Zhang, Y; Zhao, LZ; Zhao, Y; Zou, Z | 1 |
| Chen, A; DePaoli, A; Fanget, M; Fox, M; Guo, W; Haldankar, R; Humphrey, M; Kaplan, DD; Kekatpure, A; Kutach, A; Li, D; Lindhout, DA; Liu, W; Liu, Z; Matern, H; Mondal, K; Ngan, I; Pedersen, O; Shen, D; Solloway, MJ; Song, B; Tang, J; Tian, H; Wang, Y; Winans, B; Wu, H; Xi, Y; Yang, H; Younis, H; Zha, J; Zhou, M | 1 |
| Meamar, R; Rad, MG; Sharifi, M; Soltani, N | 1 |
| Andrews, JC; Arora, P; Bailey, KR; Cobelli, C; Dalla Man, C; Laurenti, MC; Matveyenko, A; Rizza, RA; Vella, A | 1 |
| Chapman, I; Giezenaar, C; Horowitz, M; Jones, KL; Lange, K; Oberoi, A; Rigda, RS; Soenen, S | 1 |
| Chen, J; Grayson, TB; Jing, G; Jo, S; Lu, B; Shalev, A; Xu, G | 1 |
| Bao, YR; Cho, YH; Han, YE; Kang, CW; Koo, J; Ku, CR; Lee, EJ; Oh, JH | 1 |
| Eguchi, H; Fujita, Y; Horii, T; Ishibashi, C; Kawata, S; Kozawa, J; Miyagawa, JI; Nammo, T; Ozawa, H; Shimomura, I; Yoneda, S | 1 |
| Han, C; Jiang, Y; Ma, W; Qiao, A; Qin, G; Yan, B; Zhou, J | 1 |
| Holst, JJ; Wewer Albrechtsen, NJ; Winther-Sørensen, M | 1 |
| Åkertröm, T; Bouman, SD; Bowler, A; Brand, CL; Cappelen, KA; Demozay, D; Egebjerg, T; Eliasen, IP; Hansen, BF; Hennen, S; Hoeg-Jensen, T; Hummelshøj, T; Hvid, H; Ingvorsen, C; Jensen, S; McGuire, J; Olsen, GS; Pedersen, TÅ; Poulsen, BR; Roed, NK; Stidsen, CE; Tiainen, P | 1 |
| Chen, W; Dai, Y; Li, H; Wu, G; Xu, R; Yin, Z; Zhang, H | 1 |
| Holst, JJ | 1 |
| Gulati, S; Misra, A; Pandey, RM; Sati, HC; Sharma, M; Tiwari, R; Upadhyay, AD | 1 |
| Chen, X; DeFronzo, RA; Merovci, A; Tripathy, D | 1 |
| Dai, Z; Dong, LQ; Liu, F; Liu, W; Ryu, J; Sun, LZ; Wang, Y; Xiao, Y; Yan, Y; Zhang, D; Zhang, R; Zhou, Z; Zou, H | 1 |
| Deguchi-Horiuchi, H; Lee, EY; Manabe, I; Miki, T; Suzuki, S; Tanaka, T; Yamanaka, N; Yokote, K | 1 |
| Bloom, SR; Campbell, JE; Cherrington, AD; Dean, ED; Finan, B; Gluud, LL; Holst, JJ; Knop, FK; Müller, TD; Tan, TM; Wewer Albrechtsen, NJ | 1 |
| Agranovich, B; Assa, M; Avrahami, D; Bernal-Mizrachi, E; Cerasi, E; Glaser, B; Gottlieb, E; Helman, A; Jackson, F; Kadosh, L; Kogot-Levin, A; Leibowitz, G; Malka, A; Piran, R; Riahi, Y | 1 |
| Hu, R; Jois, SV; Xu, L; Zhang, L | 1 |
| Cheng, D; Dang, P; Li, J; Li, Z; Pan, D; Song, W; Yuan, Y; Zhao, T | 1 |
| Chen, S; Klein, S; Scherer, PE; Smith, GI; Stern, JH; Unger, RH | 1 |
| Alvarez-Jimenez, R; Burggraaf, K; Masroor, S; Peletier, LA; Peletier, MA; van Dongen, MGJ | 1 |
| Chen, Y; Hu, C; Hu, M; Hu, Y; Li, D; Li, X; Liao, S; Liu, B; Liu, J; Lu, Y; Lv, X; Qian, Q; Tan, M; Wang, Y; Wu, D; Xiong, X; Zhang, D; Zhang, Z | 1 |
| Jiang, B; Jin, J; Liu, P; Sheng, L; Song, Y; Zhang, H; Zhong, Y; Zhou, H | 1 |
| Barg, S; Gandasi, NR; Lund, PE; Omar-Hmeadi, M; Tengholm, A | 1 |
| Basu, A; Basu, R; Carter, RE; Yadav, Y | 1 |
| Baldi, S; Frascerra, S; Mengozzi, A; Natali, A; Nesti, L; Tricò, D | 1 |
| Chen, W; Cui, J; Shang, A; Wang, W | 1 |
| Fan, X; Gong, J; Jun, H; Li, G; Liu, S; Ma, Y; Rui, L; Wang, J; Weinman, SA; Wu, J; Yin, L | 1 |
| Abiru, N; Akazawa, S; Haraguchi, A; Horie, I; Ito, A; Kamada, A; Kawakami, A; Miwa, M; Nakashima, Y; Natsuda, S; Niri, T; Sako, A; Shigeno, R | 1 |
| Feng, C; Ge, Y; Le, G; Li, B; Shi, Y; Sun, J; Tang, X; Yang, Y | 1 |
| Flatt, AJS; Greenbaum, CJ; Rickels, MR; Shaw, JAM | 1 |
| Calzone, F; Lyerly, HK; Morse, MA; Osada, T; Thai, D; Wang, J; Yan, H | 1 |
| Ahrén, B | 1 |
| Engelhardt, JF; Gibson-Corley, KN; He, N; Liang, B; Norris, AW; Sun, X; Uc, A; Yi, Y | 1 |
| Hernández-Muñoz, R; Luna-Castro, M; Martiñón-Gutiérrez, G | 1 |
| Boriboun, C; Deng, J; Habegger, KM; Kim, T; Ma, W; Ma, YC; Qiao, A; Qin, G; Qiu, H; Richard, S; Song, Y; Xu, S; Yan, B; Yang, L; Zhang, C; Zhang, E; Zhang, J; Zhou, J | 1 |
| Broughton, KS; LeMieux, MJ; Rao, M; Zumbro, EL | 1 |
| Choi, H; Jun, HS; Lee, CY; Maeng, HJ; Mee Lee, K; Nguyen, TT; Park, EY; Shin, D | 1 |
| Li, Q; Li, W; Liu, R; Long, H; Muhindo, EM; Sui, W; Wu, T; Zhang, M; Zhang, Y; Zhao, Y | 1 |
| Binkowski, S; Davis, EA; Harray, AJ; Horowitz, M; Jones, T; Keating, BL; King, BR; Paramalingam, N; Smart, CEM; Smith, G; Standfield, S | 1 |
| Ameneiro, C; Beiroa, D; Bernardo, G; Bilbao, J; Bravo, SB; Carneiro, C; Cho, JW; Coppari, R; Cuñarro, J; Da Silva Lima, N; Dieguez, C; Dp Chantada-Vazquez, M; Fernandez, U; Fernández-Ramos, D; Ferno, J; Fidalgo, M; Fondevila, MF; Fruhbeck, G; Garcia-Vence, M; Gonzalez-Rellan, MJ; Guallar, D; Herzig, S; Iglesias, C; López, M; Lopitz-Otsoa, F; Martinez-Chantar, ML; Mato, JM; Millet, O; Müller, TD; Nogueiras, R; Novoa, E; Perez-Fernandez, R; Porteiro, B; Rodríguez, A; Sabio, G; Senra, A; Seoane, S; Tovar, S; Varela-Rey, M; Veyrat-Durebex, C; Vidal, A; Woodhoo, A; Yang, WH | 1 |
| Lund, A | 1 |
| Jung, HS; Kim, M; Kim, TK; Kim, TN; Kwon, MJ; Lee, EJ; Lee, SH; Park, JH; Rhee, BD; Shin, HM | 1 |
| DeFronzo, R; Gaggini, M; Gastaldelli, A | 1 |
| Castellani, LN; Charron, MJ; Peppler, WT; Sutton, CD; Whitfield, J; Wright, DC | 1 |
| Higashihara, E; Horie, S; Kugita, M; Nagao, S; Nishii, K; Suzuki, A; Yamaguchi, T; Yuzawa, Y | 1 |
| Díaz-Villaseñor, A; Palacios-González, B; Torres, N; Tovar, AR; Tovar-Palacio, C; Velázquez-Villegas, LA | 1 |
| Jung, H; Kim, MK; Kim, TK; Kim, TN; Kwon, MJ; Lee, E; Lee, SH; Park, JH; Rhee, BD; Shin, HM | 1 |
| Cai, X; Dai, Y; Huang, W; Huang, X; Lin, H; Qian, H; Sun, L; Yang, B; Zhang, B; Zhou, J | 1 |
| Ali, M; Anjum, MS; Butt, H; Khan, SN; Mehmood, A; Riazuddin, S | 1 |
| Marks, V | 1 |
| Eberhard, D; Heiss, C; Klüppel, C; Lammert, E; Mayatepek, E; Meissner, T; Mrugala, J; Welters, A; Wörmeyer, L | 1 |
| Bouchi, R; Hashimoto, K; Izumiyama, H; Masuda, S; Minami, I; Murakami, M; Ogawa, Y; Okuma, H; Takeuchi, T; Yoshimoto, T | 1 |
| Girard, J | 1 |
| Chen, S; Cullis, PR; Ho, JSS; Kieffer, TJ; Neumann, UH; Tam, YYC | 1 |
| Bailey, KR; Cobelli, C; Man, CD; Rizza, RA; Shah, M; Sharma, A; Varghese, RT; Vella, A | 1 |
| Carria, L; Cengiz, E; Galderisi, A; Sherr, J; Tamborlane, W; Tichy, E; VanName, M; Weinzimer, S; Weyman, K; Zgorski, M | 1 |
| Coudriet, GM; Fischbach, S; Fusco, J; Gittes, GK; Guo, P; Piganelli, JD; Prasadan, K; Ramachandran, S; Shiota, C; Witkowski, P; Xiao, X; Zhang, T | 1 |
| Horowitz, M; Jones, KL; Marathe, CS; Rayner, CK; Wu, T | 1 |
| Chang, X; Cui, H; Guo, Y; Wang, C; Zeng, H | 1 |
| Bloom, SR; Scott, RV | 1 |
| Trautmann, ME; Vora, J | 1 |
| Birnbaum, MJ; Blatnik, M; Cárdenas, C; Foskett, JK; Holland, WL; Jatkar, A; Lu, W; Miller, RA; Park, JO; Pirman, DA; Rabinowitz, JD; Shi, Y; Wan, M; Wu, H; Zhang, Y | 1 |
| Ahrén, B; Farngren, J; Persson, M | 1 |
| Morris, A | 1 |
| Knop, FK | 1 |
| Arai, Y; Hasegawa, K; Itazaki, S; Kasai, Y; Katsumata, Y; Matsunari, H; Nagashima, H; Nagaya, M; Nakano, K; Okamoto, K; Umeki, I; Umeyama, K; Watanabe, M | 1 |
| He, Z; Hou, X; Hu, C; Jia, W; Jiang, F; Wang, J; Wang, S; Zhang, R | 1 |
| Ishiwata, Y; Kimura, Y; Nagata, M; Takahashi, H; Yasuhara, M | 1 |
| Alada, ARA; Oyebola, DDO; Shittu, ST | 1 |
| D'Alessio, D; Dimarchi, R; Habegger, K; Haller, A; Holland, J; Khrisna, R; Perez-Tilve, D; Rivero-Gutierrez, B; Yates, E | 1 |
| Li, D; Li, L; Ma, L; Shang, Y; Shen, C; Yu, Y; Zhao, D | 1 |
| Gilbert, RE; Jin, T; Thai, K; Woo, M; Zhang, Y | 1 |
| Adam, J; Ashcroft, FM; Brereton, M; Chibalina, MV; Hamilton, A; Haythorne, E; Knudsen, JG; Mulder, H; Ramracheya, R; Rorsman, P; Spégel, P; Tarasov, AI; Zhang, Q | 1 |
| Gao, F; Han, J; Hu, D; Jia, Y; Li, J; Qin, X; Xie, W; Xu, J; Yang, H; Zhang, X; Zhu, H; Zhu, L | 1 |
| Ozkan, H; Ozmen, O; Topsakal, S | 1 |
| Cherney, DZ; Lovshin, JA | 1 |
| Dash, S; Floh, A; Lee, SJ; Stahel, P; Sud, SK | 1 |
| Abdul-Ghani, M; Basu, R; DeFronzo, RA; Merovci, A; Tripathy, D | 1 |
| Galsgaard, KD; Holst, JJ; Kjeldsen, SAS; Pedersen, J; Rosenkilde, MM; Wewer Albrechtsen, NJ; Winther-Sørensen, M | 1 |
| Della Rossa, F; Klickstein, I; Russell, J; Shirin, A; Sorrentino, F | 1 |
| Ångerman, S; Kuisma, M; Nurmi, J; Pietiläinen, K; Salo, A; Vihonen, H | 1 |
| Dallaqua, B; Damasceno, DC; Gallego, FQ; Iessi, IL; Miranda, CA; Pando, RH; Rocha, NS; Sinzato, YK; Volpato, GT | 1 |
| Bhansali, A; Bhansali, S; Bhat, K; Dutta, P; Kochhar, R; Kurpad, AV; Mudaliar, S; Mukherjee, KK; Sachdeva, N; Shekhawat, VS; Sinha, SK; Vaiphei, K | 1 |
| Matschinsky, FM; Wilson, DF | 1 |
| Barella, LF; Cui, Y; Dattaroy, D; Doliba, NM; Hochgeschwender, U; Kaestner, KH; Matschinsky, FM; Pham, J; Roth, BL; Wang, L; Wess, J; Wilkins, KJ; Zhu, L | 1 |
| Alonso-Magdalena, P; Bru-Tari, E; Cobo-Vuilleumier, N; Dos Santos, RS; Gauthier, BR; Marroqui, L; Nadal, A; Quesada, I | 1 |
| Checklin, HL; Horowitz, M; Jones, KL; Ma, J; Meyer, JH; Rayner, CK; Stevens, JE; Wishart, JM | 1 |
| Franklin, ZJ; Irwin, N; O'Harte, FP | 1 |
| Bazotte, RB; Curi, R; de Castro R Marques, A; Minguetti-Câmara, VC; Obici, S; Tavoni, TM | 1 |
| Bakhtiani, PA; Castle, JR; El Youssef, J; Ward, WK; Zhao, LM | 1 |
| Bikopoulos, G; Ceddia, RB; Curi, R; Hung, S; Patterson, JD; Pistor, KE; Vitzel, KF | 1 |
| Chodavarapu, H; Elased, KM; Grobe, N; Madhu, M; Salem, ES; Somineni, HK | 1 |
| Armstrong, D; Burke, P; Ciaraldi, TP; Henry, RR; Ligueros-Saylan, M; Mudaliar, S | 1 |
| Cheng, Y; Dong, L; Fu, X; Han, W; Hao, H; Hou, Q; Liu, H; Liu, J; Mu, Y; Shen, J; Ti, D; Tong, C; Zhao, Y | 1 |
| Damian, V; Dorfman, MD; Guyenet, SJ; Matsen, ME; Meek, TH; Morton, GJ; Nguyen, HT; Taborsky, GJ | 1 |
| Fujimoto, M; He, P; Ishibashi, R; Ishikawa, T; Kawamura, H; Kobayashi, K; Okabe, E; Onishi, S; Takemoto, M; Watanabe, K; Yamaga, M; Yokote, K | 1 |
| Li, XC; Zhuo, JL | 1 |
| Bojsen-Møller, KN; Dirksen, C; Hansen, DL; Holst, JJ; Jacobsen, SH; Jørgensen, NB; Kristiansen, VB; Madsbad, S; Naver, LS; Worm, D | 1 |
| Avezza, F; Bianchi, R; Canta, A; Carozzi, V; Cavagnini, C; Cavaletti, G; Chiorazzi, A; Figliuzzi, M; Lauria, G; Lombardi, R; Marmiroli, P; Meregalli, C; Oggioni, N; Porretta-Serapiglia, C; Remuzzi, A; Sala, B | 1 |
| Berglund, ED; Elmquist, JK; Kim, MH; Lee, CE; Liu, C; Liu, T; Sohn, JW; Vianna, CR; Williams, KW; Xu, Y | 1 |
| Cho, KY; Nakamura, A; Nomoto, H; Ono, Y | 1 |
| Calanna, S; Christensen, MB; Holst, JJ; Knop, FK; Vilsbøll, T | 1 |
| Breitschaft, A; Darstein, C; Golor, G; Hermosillo Reséndiz, K; Hu, K | 1 |
| Abdul-Ghani, MA; Daniele, G; DeFronzo, RA; Eldor, R; Fiorentino, TV; Merovci, A; Norton, L; Perez, Z; Solis-Herrera, C; Tripathy, D; Xiong, J | 1 |
| Bernhard, N; Connolly, BL; McAlpine, K; Moineddin, R | 1 |
| Condren, AB; Donahue, EP; Farmer, TD; Healey, EC; Kim, K; McCoy, GA; O'Brien, TP; Printz, RL; Shiota, M; Ueta, K | 1 |
| Fujigaki, Y; Fujikura, T; Isobe, S; Iwakura, T; Kato, A; Naito, Y; Ohashi, N; Ono, M; Sakao, Y; Tsuji, N; Tsuji, T; Yasuda, H | 1 |
| Alonso-Magdalena, P; Fuentes, E; Marroquí, L; Merino, B; Nadal, A; Quesada, I | 1 |
| Basu, A; Basu, R; Carter, RE; Cobelli, C; Kudva, YC | 1 |
| Christensen, CS; Karstoft, K; Pedersen, BK; Solomon, TP | 1 |
| Bloom, SR; Cegla, J; Chambers, ES; Cuenco, J; Ghatei, MA; Hussein, M; Jones, B; Kenkre, J; Lim, CT; McCullough, KA; Meeran, K; Minnion, J; Parvizi, N; Tan, TM; Tharakan, G; Troke, RC | 1 |
| Cantwell, M; Heptulla, RA; Ramchandani, N; Renukuntla, VS; Trast, J | 1 |
| Ang, M; Linn, T | 1 |
| Basu, A; Basu, R; Bharucha, AE; Carter, RE; Cobelli, C; Hinshaw, L; Kudva, YC; Mallad, A; Man, CD; Schiavon, M | 1 |
| Birnbaum, MJ; Boudaba, N; Campbell, DG; Deak, M; Foretz, M; Göransson, O; Gourlay, R; Gray, NS; Kaestner, KH; Marion, A; Patel, K; Peggie, M; Sakamoto, K; Sutherland, C; Titchenell, P; Tournier, E; Viollet, B; Wan, M | 1 |
| Allister, EM; Cai, EP; Gaisano, HY; Luk, CT; Schroer, SA; Shi, SY; Wang, L; Wheeler, MB; Woo, M | 1 |
| Herzog, B; Jordi, J; Lutz, TA; Verrey, F | 1 |
| Berglund, ED; Charron, MJ; Evans, MR; Holland, WL; Lee, Y; Roth, MG; Scherer, PE; Unger, RH; Wang, MY; Yu, X | 1 |
| Calle, RA; Fryburg, DA; Ghosh, A; Lee, DS; Raymond, RH; Robertson, RP; Savage, PJ; Shankar, SS; Vassileva, MT; Weir, GC | 1 |
| Aulinger, BA; D'Alessio, DA; Drazen, DL; Seeley, RJ; Smith, EP; Ulrich-Lai, Y; Vahl, TP; Woods, SC | 1 |
| Gui, Q; Wang, XD; Wang, Y; Zhu, YD; Zhu, YX | 1 |
| Deacon, CF; Feinle-Bisset, C; Heruc, GA; Horowitz, M; Little, TJ; Luscombe-Marsh, N; Rayner, CK | 1 |
| De Jesus, DF; Dirice, E; Hu, J; Kahraman, S; Kulkarni, RN | 1 |
| Nakamura, S; Nakazato, M; Sakoda, H; Tsubouchi, C; Tsuchimochi, W; Ueno, H; Yamashita, E | 1 |
| Carr, MC; Hompesch, M; Jones-Leone, A; Matthews, J; Morrow, L; Reinhardt, RR; Young, M; Zhi, H | 1 |
| Abdulla, H; Atherton, PJ; Idris, I; Phillips, B; Smith, K; Wilkinson, D | 1 |
| Furukawa, A; Ishihara, H; Kosuda, M; Nakazaki, M; Otsuka, Y; Yamaguchi, S | 1 |
| Baretić, M; Troskot, R | 1 |
| Holst, JJ; Karstoft, K; Knudsen, SH; Pedersen, BK; Solomon, TP; Winding, K | 2 |
| Escalada, FJ | 1 |
| Benoit, YD; Gudas, LJ; Trasino, SE | 1 |
| Bassil, M; Burgos, SA; Chevalier, S; Gougeon, R; Lamarche, M; Marliss, EB; Morais, JA | 1 |
| Almokayyad, RM; Gannon, MC; Nuttall, FQ | 1 |
| Farmer, TD; Havlik, AE; Jenkins, EC; McCoy, GA; Nass, ER; Nicholson, WE; O'Brien, TP; Printz, RL; Shiota, M | 1 |
| Andersen, ML; Fredheim, S; Hansen, L; Holst, JJ; Johannesen, J; Mortensen, HB; Nielsen, LB; Pipper, C; Pörksen, S; Svensson, J; Thomsen, J | 1 |
| Deacon, CF; Hamamoto, Y; Hamasaki, A; Harada, N; Hirano, T; Holst, JJ; Inagaki, N; Iwasaki, M; Kuroe, A; Kurose, T; Lee, S; Murotani, K; Seino, Y; Watanabe, K; Yabe, D; Yamane, S | 1 |
| Annink, CE; Chapman, MJ; Cousins, CE; Deane, AM; Horowitz, M; Jones, KL; Kar, P; Meier, JJ; Nauck, MA | 1 |
| Adin, CA; Borin-Crivellenti, S; Gilor, C; Hall, MJ; Lakritz, J; Rajala-Schultz, P; Rudinsky, AJ | 1 |
| Cubelo, A; Dorfman, MD; Fischer, JD; Kumar, MR; Matsen, ME; Meek, TH; Morton, GJ; Taborsky, GJ | 1 |
| Deeg, MA; Fu, H; Garhyan, P; Kelly, RP; Lim, CN; Loh, MT; Pinaire, JA; Prince, MJ; Raddad, E | 1 |
| Heden, TD; Kanaley, JA; Leidy, HJ; Liu, Y; Nyhoff, LM; Park, YM; Thyfault, JP | 1 |
| Campbell, MD; Gonzalez, JT; Rumbold, PL; Shaw, JA; Stevenson, EJ; Walker, M; West, DJ | 1 |
| Abadpour, S; Foss, A; Gorman, T; Hoeyem, M; Johansson, L; Korsgren, O; Sahraoui, A; Scholz, H; Skrtic, S; Smith, DM; Winzell, MS | 1 |
| Chen, MC; Hsieh, CH; Hsu, KC; Hung, CC; Wang, TY | 1 |
| Chang, BC; Chen, LM; Ren, HZ; Shan, CY; Wang, Y; Xu, YG; Yang, JH; Yang, YH; Zheng, MY | 1 |
| Coleman, MP; Cooper, E; Mundinger, TO; Taborsky, GJ | 1 |
| Cox, AR; Hess, RS; Kushner, JA; Lam, CJ; Rankin, MM; Shields, EJ; Van Winkle, TJ | 1 |
| Ahren, B; Bar-Dayan, Y; Froy, O; Jakubowicz, D; Landau, Z; Wainstein, J | 1 |
| Challet, E; Foppen, E; Jha, PK; Kalsbeek, A | 1 |
| Albury-Warren, TM; Altomare, DA; Masternak, MM; Pandey, V; Spinel, LP | 1 |
| Cefalo, CM; Conte, C; Giaccari, A; Kulkarni, RN; Mari, A; Mezza, T; Moffa, S; Pontecorvi, A; Sorice, GP; Sun, VA | 1 |
| Abiko, A; Atageldiyeva, KK; Fujita, Y; Haneda, M; Honjo, J; Kieffer, TJ; Makino, Y; Takeda, Y; Takiyama, Y; Yanagimachi, T | 1 |
| Covey, SD; Denroche, HC; Kieffer, TJ; Mojibian, M; Neumann, UH | 1 |
| Choi, K; Weber, JM | 1 |
| Scheen, AJ | 1 |
| Cho, YM; Kim, EK; Kim, LK; Oh, TJ | 1 |
| Centofanti, B; Chen, Z; Gonzalez, FJ; Periyasamy, S; Ramakrishnan, SK; Rui, L; Shah, YM; Takahashi, S; Uhler, MD; Weisz, K; Zhang, H | 1 |
| Engelhardt, JF; Gibson-Corley, K; Hara, M; He, N; Liang, B; Norris, AW; Ode, KL; Philipson, LH; Sun, X; Tyler, SR; Uc, A; Wang, K; Xie, W; Yi, Y | 1 |
| Kulina, GR; Rayfield, EJ | 1 |
| Brozinick, JT; Chen, S; Geldenhuys, WJ; Kusminski, CM; Li, WH; Sanders, PE; Scherer, PE; Spurgin, SB; Sun, K; Unger, RH; Wang, QA; Ye, R | 1 |
| Blauw, H; DeVries, JH; Koops, R; van Bon, AC | 1 |
| Gromada, J; Harp, JB; Yancopoulos, GD | 1 |
| Christensen, MB | 1 |
| Gylfe, E | 1 |
| Briant, L; Rorsman, P; Salehi, A; Vergari, E; Zhang, Q | 1 |
| Ishiwata, Y; Nagata, M; Nakajima, M; Negishi, K; Takahashi, H; Takahashi, Y; Yasuhara, M | 1 |
| Cantwell, M; Heptulla, RA; Ilkowitz, JT; Katikaneni, R; Ramchandani, N | 1 |
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| Hinds, A; Machida, H; Parsons, HG; Sheehan, AG | 1 |
| Leclercq-Meyer, V; Malaisse, WJ; Marchand, J | 1 |
| Fujiwara, T; Fukami, M; Fukuda, K; Horikoshi, H; Wada, M; Yoshioka, S; Yoshioka, T | 1 |
| Anderson, RA; Bryden, NA; Canary, JJ; Polansky, MM | 1 |
| Abumrad, NN; Badr, KF; Jacobson, HR; Nammour, TM; Williams, PE | 1 |
| Caruso, M; Divertie, GD; Jensen, MD; Miles, JM | 1 |
| Butler, PC; Rizza, RA | 1 |
| Diem, P; Klein, DJ; Levitt, MD; Moran, A; Robertson, RP | 1 |
| Faber, OK; Gjessing, HJ; Pedersen, O; Reinholdt, B | 1 |
| Kawamori, R | 1 |
| Lundgren, J; Mans, A; Siesjö, BK | 1 |
| Hanley, RM | 1 |
| Aslan, SM; Atiea, JA; Luzio, S; Owens, DR | 1 |
| Attvall, S; Fowelin, J; Lager, I; Smith, U; von Schenck, H | 1 |
| Chen, YD; Hollenbeck, C; Johnston, P; Reaven, GM; Sheu, W | 1 |
| Kagawa, S; Matsuoka, A; Takao, F; Yamashita, K | 1 |
| Clutter, WE; Cryer, PE; Havlin, CE; Hirsch, IB; Shah, SD; Smith, LJ | 1 |
| Koh, CS; Lee, HK; Lee, KU; Min, HK; Park, KS; Rhee, BD | 1 |
| Blickle, JF; Bockel, R; Doffoel, M; Fratte, S; Hirsch, E; Pinget, M; Reville, M; Roze, F; Vetter, D; Winiszewski, P | 1 |
| Buonocore, S; D'Onofrio, F; Gentile, S; Lefèbvre, PJ; Paolisso, G; Scheen, A; Sgambato, S; Varricchio, M | 1 |
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| Flynn, T; Gumbiner, B; Henry, RR; Thorburn, AW | 1 |
| Möhrle, W; Richter, WO; Ritter, MM; Schwandt, P | 1 |
| Bihoreau, MT; Ferré, P; Girard, J; Jame, P; Ktorza, A; Nurjhan, N; Picon, L | 1 |
| Akaji, K; Kii, E; Manabe, T; Ohshio, G; Tanaka, Y; Tobe, T; Yajima, H; Yoshimura, T | 1 |
| Gotoh, M; Iguchi, A; Mano, T; Matsunaga, H; Miura, H; Sakamoto, N; Uemura, K; Yatomi, A | 1 |
| Elahi, D; Meneilly, GS; Minaker, KL; Rowe, JW; Sclater, AL | 1 |
| Albrecht, GH; Arbuckle, S; Goldman, J; Mahan, E; Slavin, BG; Soejima, K; Zeidler, A | 1 |
| Iguchi, A; Kawahara, H; Kunoh, Y; Miura, H; Sakamoto, N; Tamagawa, T; Uemura, K; Yatomi, A | 1 |
| Fujii, T; Inoue, S; Nagai, K; Nakagawa, H | 1 |
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| Briand, R; Gagné, J; Yamaguchi, N | 1 |
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| Gotoh, M; Iguchi, A; Matsunaga, H; Nomura, T; Ohuchi, M; Sakamoto, N | 1 |
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| Klaff, LJ; Taborsky, GJ | 1 |
| Efendić, S; Grill, V; Gutniak, M; Wiechel, KL | 1 |
| Bell, PM; Firth, RG; Rizza, RA | 2 |
| Fujiwara, T; Nagai, K; Nakagawa, H; Takagi, S | 1 |
| Gotoh, M; Honmura, A; Iguchi, A; Matsunaga, H; Sakamoto, N; Yanase, M; Yatomi, A | 1 |
| Nagai, K; Nakagawa, H; Yamamoto, H | 1 |
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| Ceriello, A; Cozzolino, D; D'Onofrio, F; Giugliano, D; Salvatore, T; Torella, R | 1 |
| Kunii, Y; Marubashi, S; Sasaki, H; Tominaga, M | 1 |
| Beylot, M; Cohen, R; Dechaud, H; Mornex, R; Riou, JP; Sautot, G; Serusclat, P | 1 |
| Abraham, G; Leiter, LA; Marliss, EB; Mitchell, TH; Schiffrin, A | 1 |
| Hirata, Y; Inoue, Y; Matsumoto, H; Tasaka, Y | 1 |
| Kagawa, S; Matsuoka, A; Sakamoto, K; Takao, F | 1 |
| DeFronzo, RA; Groop, L; Groop, PH; Luzi, L; Melander, A; Ratheiser, K; Simonson, DC | 1 |
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| Futenma, A; Gotoh, M; Iguchi, A; Kato, K; Nakamura, S; Sakamoto, N; Yanase, M | 1 |
| Farrell, PA; Galbo, H; Mikines, KJ; Sonne, B; Tronier, B | 1 |
| Elahi, D; Miyoshi, H; Peters, EJ; Shulman, GI; Wolfe, MH; Wolfe, RR | 1 |
| Ahrén, B; Efendić, S; Lindskog, S; Tatemoto, K | 1 |
| Leahy, JL; Weir, GC | 1 |
| Cryer, PE; Havlin, CE; Levandoski, LA; Santiago, JV; Tordjman, KM; White, NH | 1 |
| Dubuc, PU | 1 |
| Hirota, M; Mizuno, A; Ohboshi, C; Shima, K; Shimizu, I | 1 |
| Christiansen, J; Holst, JJ; Loud, FB; Rehfeld, JF | 1 |
| Helderman, JH; Imamura, T; Koffler, M; Santeusanio, F | 1 |
| Cooper, HE; Deal, DA; Leahy, JL; Weir, GC | 1 |
| Bell, PM; Firth, RG; Hansen, I; Marsh, HM; Rizza, RA | 1 |
| Castells, S; Rao, SP | 1 |
| Pildes, RS; Pyati, SP | 1 |
| Karam, JH; Nolte, MS; Salamon, E; Sanz, N | 1 |
| Carlson, DE; Gann, DS; McLeod, MK | 1 |
| Andersen, DK; Brunicardi, FC; Druck, P; Elahi, D; Goulet, RJ; Sun, YS | 1 |
| Franz, MJ | 1 |
| Arnulf, JJ; Dor, V; Galletti, PM; Hahn, C; Isetta, C; Kuntschen, FR | 1 |
| Blagovidov, DF; Danilov, MV; Ganzha, PF; Uralov, MM | 1 |
| Dimitriadis, GD; Gerich, JE; Go, VL; Tessari, P | 1 |
| Grundy, S; McGarry, JD; Starke, A; Unger, RH | 1 |
| Daligcon, BC; Oyama, J | 1 |
| Ferre, P; Girard, JR; Ktorza, A; Nurjhan, N; Picon, L | 1 |
| Jobidon, C; Nadeau, A; Rousseau-Migneron, S; Tancrède, G; Trudel, D | 1 |
| DeFronzo, RA; Smith, JD | 1 |
| Baer, AR; Dupre, J | 1 |
| Nadeau, A; Nadeau, S; Rousseau-Migneron, S | 1 |
| Bahn Zobbe, V; Hartvig Hartsen, S; Krause, S; Rasmussen, D; Rygaard, H; Strandberg, C; Thomsen, HS | 1 |
| Fish, RE; Nelson, KM; Spitzer, JA | 1 |
| Brennan, MF; Meguid, MM | 1 |
| Agot, H; Alric, R; Loubatières, AL; Loubatières-Mariani, MM; Ribes, G | 1 |
| Marks, V; Marri, G; Samols, E; Tyler, J | 1 |
| Danilevicius, Z | 1 |
| Lenti, G | 1 |
| Beloff-Chain, A; Findlay, JA; Lever, JD; Rookledge, KA | 1 |
| Adámek, R; Saxl, O; Snopková, J; Teyschl, O; Vítek, B; Vognárek, J | 1 |
| Dupré, J; Eisentraut, AM; Ketterer, H; Unger, RH | 1 |
| Balagura, S | 1 |
| Conn, JW; Fajans, SS; Floyd, JC; Harrison, TS; Knopf, RF; Thiffault, CA | 1 |
| Catellier, C; Plamondon, C; Ringuet, J; Rivière, L | 1 |
| AvRuskin, TW; Coran, AG; Crigler, JF | 1 |
| Hellman, B; Idahl, LA | 2 |
| Bricaire, H; Luton, JP; Pandos, P; Strauch, G | 1 |
| Bergström, J; Hultman, E; Nilsson, LH | 1 |
| Lernmark, A | 1 |
| Bernier, JJ | 1 |
| Hostetler, KY; Williams, HR | 1 |
| Daniel, RR; Faloona, GR; Freinkel, N; Metzger, BE; Nitzan, M; Unger, RH | 1 |
| Fussgänger, RD; Laube, H; Pfeiffer, EF | 1 |
| Faloona, GR; Hutcheson, DR; Leshin, SJ; Unger, RH; Willerson, JT | 1 |
| Faloona, GR; Santeusanio, F; Unger, RH | 1 |
| Berson, SA; Yalow, RS | 1 |
| Schmidt, HA | 1 |
| Gomez-Acebo, J; Parrilla, R | 1 |
| Braaten, JT; Faloona, GR; Unger, RH | 1 |
| Mosin, VI | 1 |
| Späth, G | 1 |
| Frenkel, G; Kraicer, PF; Shani, J | 1 |
| Golda, W; Sieradzki, J; Szybiński, Z | 1 |
| Kerins, C; Said, SI | 1 |
| Aziz, EM; Lipsitz, PJ | 1 |
| Faloona, GR; Knochel, JP; Santeusanio, F; Unger, RH | 1 |
| Czerwinski, C; De Santis, R; Garcia, MJ; Lan, VV; Penhos, JC; Ramey, E | 1 |
| Conn, JW; Fajans, SS; Floyd, JC; Knopf, RF; Pek, S; Prchkov, VK | 1 |
| Boucher, ME; Bromer, WW; Patterson, JM | 1 |
| Forsham, PH; Gerich, JE; Karam, JH | 1 |
| Neumann, B; Weber, B | 1 |
| Jablońska, A | 1 |
| Faloona, GR; Lindsey, CA; Moylan, JA; Pruitt, BA; Unger, RH; Wilmore, DW | 1 |
| Duprey, J; Lubetzki, J | 1 |
| Aubry, F; Davignon, J; Marcel, YL | 1 |
| Patel, DA; Pildes, RS; Ramamurthy, RS | 1 |
| Fanska, RE; Frankel, BJ; Gerich, JE; Gerritsen, GC; Grodsky, GM; Hagura, R | 1 |
| Avruskin, TW; Juan, CS; Tang, SC | 1 |
| Marques, M | 1 |
| Lawrence, AM; Nevis, HC; Stiller, A; Woll, J | 1 |
| Assan, R; Pignard, P; Rosselin, G; Tchobroutsky, G | 1 |
| Lawrence, AM | 1 |
| Marks, V; Salmols, E | 1 |
| Kaneto, A; Kosaka, K; Mizuno, Y; Tasaka, Y | 1 |
| Adam, PA; Kornhauser, D; Schwartz, R | 1 |
| Aguilar-Parada, E; Faloona, GR; Müller, WA; Unger, RH | 1 |
| Westman, S | 1 |
| Lampe, EW; Moberg, AW; Najarian, JS; Simmons, RL | 1 |
| Faloona, GR; Müller, WA; Unger, RH | 1 |
| Oneda, A | 1 |
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| Frohman, LA | 1 |
| Aguilar-Parada, E; Eisentraut, AM; Müller, WA; Unger, RH | 1 |
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| Baroja, IM; Diaz-Fierros, M; Marco, J; Valverde, I; Villanueva, ML | 1 |
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| Mutt, V; Said, SI | 1 |
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| Ludewig, RM; Madden, JJ; Wangensteen, SL | 1 |
| Ogawa, S; Otaka, T; Uchiyama, M; Yoshida, T | 1 |
| Ege, P; Jacobsen, M | 1 |
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| Ezdinli, EZ; Javid, R; Owens, G; Sokal, JE | 1 |
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| Aguilar-Parada, E; Eisentraut, AM; Ohneda, A; Unger, RH | 2 |
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93 review(s) available for glucagon and Hyperglycemia
| Article | Year |
|---|---|
Pathways of Glucagon Secretion and Trafficking in the Pancreatic Alpha Cell: Novel Pathways, Proteins, and Targets for Hyperglucagonemia.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin Resistance; Signal Transduction | 2021 |
The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease.
Topics: Amino Acids; Animals; Diabetes Mellitus, Type 2; Feedback; Glucagon; Glucose; Humans; Hyperglycemia; Lipids; Non-alcoholic Fatty Liver Disease | 2023 |
100 years of glucagon and 100 more.
Topics: Amino Acids; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Non-alcoholic Fatty Liver Disease | 2023 |
Pancreatic islet reserve in type 1 diabetes.
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells | 2021 |
Glucose-lowering action through targeting islet dysfunction in type 2 diabetes: Focus on dipeptidyl peptidase-4 inhibition.
Topics: Asia, Eastern; Asian People; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Metformin | 2021 |
On the role of the gut in diabetic hyperglucagonaemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin | 2017 |
Glucose kinetics: an update and novel insights into its regulation by glucagon and GLP-1.
Topics: Animals; Diabetes Mellitus, Type 2; Fasting; Gastric Emptying; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Gluconeogenesis; Glucose; Homeostasis; Humans; Hyperglycemia; Kinetics; Liver; Receptors, Glucagon; Satiation | 2017 |
NMDAR antagonists for the treatment of diabetes mellitus-Current status and future directions.
Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Drug Design; Drug Resistance, Multiple; Drugs, Investigational; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Neuralgia; Receptors, N-Methyl-D-Aspartate | 2017 |
Glucagon, a key factor in the pathophysiology of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Liver; Rodentia | 2017 |
Problem or solution: The strange story of glucagon.
Topics: Diabetes Mellitus, Type 2; Energy Metabolism; Glucagon; Humans; Hyperglycemia; Incretins; Insulin; Obesity; Receptors, Glucagon | 2018 |
Use of glucagon-like peptide-1 receptor agonists among individuals on basal insulin requiring treatment intensification.
Topics: Administration, Oral; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucagon; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Incretins; Insulin Glargine; Insulin, Long-Acting; Peptides; Postprandial Period; Treatment Outcome | 2018 |
EJE PRIZE 2018: A gut feeling about glucagon.
Topics: Diabetes Mellitus, Type 2; Enteroendocrine Cells; Fasting; Fatty Liver; Gastrointestinal Tract; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Liver; Proglucagon | 2018 |
A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Forecasting; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulins; Pancreas, Artificial | 2013 |
Current insights and new perspectives on the roles of hyperglucagonemia in non-insulin-dependent type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Humans; Hyperglycemia; Hypertension; Insulin | 2013 |
Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes.
Topics: Blood Glucose; Diabetes Mellitus; Diet; Energy Metabolism; Glucagon; Glucagon-Secreting Cells; Homeostasis; Humans; Hyperglycemia; Lipid Metabolism; Obesity; Receptors, Glucagon | 2014 |
Physiological mechanisms of action of incretin and insulin in regulating skeletal muscle metabolism.
Topics: Blood Flow Velocity; Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin; Insulin Resistance; Microcirculation; Muscle, Skeletal | 2014 |
How to fight obesity with antidiabetic drugs: targeting gut or kidney?
Topics: Anti-Obesity Agents; Bariatric Surgery; Biological Transport; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Exenatide; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glucose; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kidney Tubules, Proximal; Microvilli; Multicenter Studies as Topic; Obesity; Peptides; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Venoms; Weight Loss | 2015 |
THE ROLE OF GLUCAGON IN THE PATHOPHYSIOLOGY AND MANAGEMENT OF DIABETES.
Topics: Diabetes Mellitus; Drug Discovery; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Metabolic Networks and Pathways | 2016 |
Glucagon orchestrates stress-induced hyperglycaemia.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide-1 Receptor; Humans; Hyperglycemia; Stress, Physiological | 2016 |
Glucose-dependent insulinotropic polypeptide: effects on insulin and glucagon secretion in humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Male; Randomized Controlled Trials as Topic | 2016 |
Glucose control of glucagon secretion-'There's a brand-new gimmick every year'.
Topics: Animals; Autoimmune Diseases; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Signal Transduction; Somatostatin | 2016 |
Glucagon secretion from pancreatic α-cells.
Topics: Animals; Diabetes Mellitus, Type 2; Electrophysiology; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Mice; Models, Theoretical; Rats; Receptors, Somatostatin; Signal Transduction; Somatostatin | 2016 |
Pancreatic alpha-cell dysfunction in diabetes.
Topics: Diabetes Mellitus; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia | 2008 |
Insulin as a physiological modulator of glucagon secretion.
Topics: Animals; Glucagon; Humans; Hyperglycemia; Insulin; Islets of Langerhans | 2008 |
[New therapies for type 2 diabetes: what place for incretin-based agents and rimonabant compared to the previous ones?].
Topics: Administration, Oral; Diabetes Mellitus, Type 2; Glucagon; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Metabolic Syndrome; Metformin; Piperidines; Pyrazoles; Rimonabant; Safety; Sulfonylurea Compounds; Thiazolidinediones | 2008 |
Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Glucagon; Humans; Hyperglycemia; Receptors, Glucagon | 2009 |
Calcium channel blocker toxicity.
Topics: Adult; Assisted Circulation; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Cardiovascular Agents; Cardiovascular Diseases; Charcoal; Child, Preschool; Combined Modality Therapy; Drug Overdose; Enema; Extracorporeal Circulation; Fat Emulsions, Intravenous; Fluid Therapy; Glucagon; Heart; Humans; Hyperglycemia; Infant; Muscle, Smooth, Vascular; Plasmapheresis; Poisoning; Practice Guidelines as Topic | 2009 |
Perioperative intensive insulin therapy using artificial endocrine pancreas in patients undergoing pancreatectomy.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Humans; Hyperglycemia; Insulin Infusion Systems; Pancreatectomy; Pancreatic Polypeptide; Perioperative Care; Postoperative Complications | 2009 |
Sick day management in children and adolescents with diabetes.
Topics: Adolescent; Blood Glucose; Child; Diabetes Complications; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Infections; Insulin; Ketones; Sick Leave | 2009 |
Molecular pathways underlying the pathogenesis of pancreatic alpha-cell dysfunction.
Topics: Animals; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypertrophy; Islets of Langerhans; Models, Biological; Nervous System; Neurotransmitter Agents; Pancreas; Signal Transduction; Somatostatin | 2010 |
CREB and the CRTC co-activators: sensors for hormonal and metabolic signals.
Topics: Adipose Tissue; Animals; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Glucagon; Gluconeogenesis; Humans; Hyperglycemia; Hypothalamus; Insulin; Islets of Langerhans; Liver; Longevity; Models, Biological; Muscle, Skeletal; Phosphorylation; Signal Transduction; Trans-Activators | 2011 |
Glucagon antagonism as a potential therapeutic target in type 2 diabetes.
Topics: Biphenyl Compounds; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemic Agents; Liver; Receptors, Glucagon; Signal Transduction | 2011 |
Early milestones in glucagon research.
Topics: Animals; Biomedical Research; Glucagon; History, 20th Century; Humans; Hyperglycemia; Nobel Prize; Radioimmunoassay | 2011 |
Brain glucose sensing and neural regulation of insulin and glucagon secretion.
Topics: Autonomic Nervous System; Biological Transport; Blood Glucose; Brain; Diabetes Mellitus, Type 2; Glucagon; Glucose Transporter Type 2; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Signal Transduction | 2011 |
The role of dysregulated glucagon secretion in type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin-Secreting Cells; Liver; Mice | 2011 |
Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemia; Insulin; Mice; Models, Biological; Rats; Somatostatin | 2012 |
Safe glycemic management during closed-loop treatment of type 1 diabetes: the role of glucagon, use of multiple sensors, and compensation for stress hyperglycemia.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Pancreas, Artificial; Stress, Psychological | 2011 |
Dysglycaemia in the critically ill - significance and management.
Topics: Analysis of Variance; Biomarkers; Blood Glucose; Critical Illness; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Risk Factors | 2013 |
[Glucagon and GLP (glucagon-like peptide)].
Topics: Animals; Diabetes Mellitus; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Peptide Fragments; Peptides; Protein Precursors | 2002 |
[WHAT IS THE GLUCAGON PROBLEM?].
Topics: Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Glucagon; Hyperglycemia; Hyperinsulinism; Metabolism; Pharmacology; Physiology; Research | 1963 |
EXPERIMENTAL DIABETES AND THE MODE OF ACTION OF THE SULFONYLUREAS. WITH SOME SPECULATIONS ON THE PREVENTION OF DIABETES.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cortisone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids; Fluoroacetates; Genetics, Medical; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Leucine; Pharmacology; Pregnancy; Prolactin; Rats; Research; Sulfonylurea Compounds; Tolbutamide | 1964 |
THE HYPERGLYCEMIC ACTION OF HORMONES.
Topics: Adrenal Cortex Hormones; Glucagon; Growth Hormone; Hormones; Human Growth Hormone; Hyperglycemia; Insulin; Pharmacology; Proteins | 1964 |
[MORPHOLOGICAL PROBLEMS IN DIABETES RESEARCH].
Topics: Adolescent; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islands; Islets of Langerhans; Obesity; Pathology; Research | 1964 |
A lesson in early morning hyperglycemia.
Topics: Blood Glucose Self-Monitoring; Circadian Rhythm; Diabetes Complications; Dose-Response Relationship, Drug; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; Metformin; Somatomedins; Time Factors | 2004 |
[Impaired hepatic glucose metabolism].
Topics: Glucagon; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Obesity; Postprandial Period | 2005 |
Glucagon: the effects of its excess and deficiency on insulin action.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Insulin | 2006 |
The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications.
Topics: Animals; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Postprandial Period; Receptors, Glucagon | 2007 |
Gastric inhibitory polypeptide.
Topics: Adolescent; Adult; Diabetes Mellitus; Gastric Inhibitory Polypeptide; Gastric Juice; Gastrointestinal Hormones; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Malabsorption Syndromes; Obesity; Somatostatin | 1980 |
The CNS control of glucose metabolism.
Topics: Adolescent; Adult; Animals; Blood Glucose; Brain Injuries; Brain Neoplasms; Catecholamines; Central Nervous System; Child; Diabetes Mellitus; Female; Glucagon; Glucocorticoids; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypothalamus; Insulin; Kinetics; Liver; Male; Middle Aged; Pituitary Hormones; Somatostatin; Spinal Cord Injuries | 1981 |
The glucagonoma syndrome: clinical features, diagnosis, and treatment.
Topics: Adenoma, Islet Cell; Adult; Amino Acids; Diagnosis, Differential; Female; Glucagon; Glucagonoma; Humans; Hyperglycemia; Insulinoma; Male; Middle Aged; Pancreatic Neoplasms; Paraneoplastic Endocrine Syndromes; Skin | 1981 |
Excessive insulin therapy: biochemical effects and clinical repercussions. Current concepts of counterregulation in type I diabetes.
Topics: Blood Glucose; Diabetes Mellitus; Epinephrine; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin | 1983 |
Islet function and stress hyperglycemia: plasma glucose and epinephrine interaction.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Feedback; Glucagon; Humans; Hyperglycemia; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Myocardial Infarction; Physical Exertion; Stress, Physiological; Surgical Procedures, Operative; Sympathetic Nervous System; Wounds and Injuries | 1984 |
[Pathophysiology and therapy of diabetic ketoacidosis and of non-ketoacidotic hyperosmolar diabetic coma].
Topics: Amino Acids; Blood Glucose; Catecholamines; Dehydration; Diabetic Coma; Diabetic Ketoacidosis; Glucagon; Growth Substances; Humans; Hydrocortisone; Hyperglycemia; Hyperglycemic Hyperosmolar Nonketotic Coma; Insulin; Osmolar Concentration; Sodium Chloride; Water-Electrolyte Imbalance | 1984 |
Hormonal changes and their influence on metabolism and nutrition in the critically ill.
Topics: Animals; Catecholamines; Critical Care; Glucagon; Gluconeogenesis; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Infections; Insulin; Nitrogen; Oxygen Consumption; Urea; Wounds and Injuries | 1982 |
Glucose metabolism and liver cirrhosis.
Topics: Catecholamines; Chronic Disease; Diabetes Mellitus, Type 2; Fatty Acids; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Insulin-Like Growth Factor I; Liver Cirrhosis; Nutrition Disorders | 1995 |
[Glucose metabolism and chronic renal insufficiency].
Topics: Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Kidney Failure, Chronic; Parathyroid Hormone | 1994 |
Central glucagon-like peptide-I in the control of feeding.
Topics: Animals; Brain; Feeding Behavior; Genes, fos; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hyperglycemia; Hyperinsulinism; Neurons; Peptide Fragments; Protein Precursors; Rats; Rats, Zucker; Receptors, Glucagon; Venoms | 1996 |
Modulation of gastric emptying as a therapeutic approach to glycaemic control.
Topics: Amino Acid Sequence; Amyloid; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gastric Emptying; Glucagon; Humans; Hyperglycemia; Islet Amyloid Polypeptide; Molecular Sequence Data; Postprandial Period; Rats | 1996 |
[Stress and glycemic control in diabetes mellitus].
Topics: Blood Glucose; Catecholamines; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Stress, Psychological | 1997 |
Metabolic abnormalities in impaired glucose tolerance.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Glucose Intolerance; Humans; Hyperglycemia; Insulin; Insulin Resistance; Middle Aged; Prevalence; Risk Factors; United States | 1997 |
Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function.
Topics: Animals; Gene Expression Regulation; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Like Growth Factor I; Islets of Langerhans | 2000 |
[Postprandial hyperglycemia. I. Physiopathology, clinical consequences and dietary management].
Topics: Absorption; Cardiovascular Diseases; Diabetes Complications; Dietary Carbohydrates; Dietary Fiber; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Kinetics; Postprandial Period; Risk Factors | 2002 |
[Postprandial hyperglycemia. II. Pharmacological approaches].
Topics: alpha-Glucosidases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Enzyme Inhibitors; Glucagon; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Postprandial Period | 2002 |
Diabetic coma: a reappraisal after five years.
Topics: Age Factors; Blood; Blood Glucose; Catecholamines; Diabetic Coma; Glucagon; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Hyperglycemia; Insulin; Ketone Bodies; Potassium | 1977 |
Somatostatin and the endocrine pancreas.
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Humans; Hydroxybutyrates; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1976 |
Hormonal interactions in the regulation of blood glucose.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dogs; Glucagon; Humans; Hyperglycemia; Insulin; Liver; Rats; Receptors, Cell Surface; Somatostatin; Stress, Physiological; Uremia | 1979 |
The role of glucagon in the endogenous hyperglycemia of diabetes mellitus.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Somatostatin | 1977 |
Diabetic regulation and its relationship to microangiopathy.
Topics: Adult; Basement Membrane; Blood Glucose; Capillaries; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Glucagon; Hemoglobin A; Humans; Hyperglycemia; Insulin; Kidney Glomerulus; Middle Aged; Muscles | 1978 |
Role of glucagon in the pathogenesis of diabetes: the status of the controversy.
Topics: Alanine; Animals; Antigens; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Proteins; Dogs; Glucagon; Glucose; Humans; Hydroxybutyrates; Hyperglycemia; Insulin; Islets of Langerhans; Ketone Bodies; Lactates; Liver; Models, Biological; Somatostatin | 1978 |
[Diet therapy of diabetes mellitus].
Topics: Circadian Rhythm; Diabetes Mellitus; Dietary Carbohydrates; Energy Intake; Glucagon; Hyperglycemia; Insulin; Lipoproteins; Obesity | 1978 |
Insulin resistance in obesity: a critical analysis at enzyme level. A review.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Glucagon; Gluconeogenesis; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Lipolysis; Liver; Mice; Muscles; Obesity; Proteins; Rats | 1979 |
The role of hepatic control of glucose homeostasis in the etiology of neonatal hypo- and hyperglycemia.
Topics: Adult; Delivery, Obstetric; Diagnosis, Differential; Female; Fetus; Glucagon; Glucose; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Hypoxia; Infant; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Infant, Small for Gestational Age; Infections; Insulin; Liver; Nutritional Requirements; Pregnancy; Stress, Physiological | 1979 |
[Etiology of diabetes (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Autoimmune Diseases; Child; Child, Preschool; Diabetes Mellitus; Endocrine System Diseases; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Islets of Langerhans; Male; Menopause; Middle Aged; Obesity; Pancreatic Diseases; Pregnancy; Sex Factors; Somatostatin; Virus Diseases | 1977 |
[Glucagon, stomach and pancreas].
Topics: Animals; Dogs; Gastric Juice; Gastric Mucosa; Gastrins; Gastrointestinal Hormones; Glucagon; Humans; Hyperglycemia; Islets of Langerhans; Pancreas; Pancreatitis; Peptic Ulcer; Secretin | 1975 |
[Possibilities of preventing diabetic angiopathy (pathogenetic factors in angiopathy)].
Topics: Animals; Diabetic Angiopathies; Epinephrine; Fructose; Glucagon; Growth Hormone; Humans; Hyperglycemia; Microcirculation; Norepinephrine; Sorbitol | 1976 |
[The role of glucagon in hyperglycemia. A review (author's transl)].
Topics: Acromegaly; Adult; Burns; Child; Cushing Syndrome; Diabetes Mellitus; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Infections; Insulin; Islets of Langerhans; Liver; Liver Cirrhosis; Myocardial Infarction; Pancreatic Diseases; Pheochromocytoma; Prediabetic State; Shock; Somatostatin | 1975 |
Carbohydrate metabolism in trauma.
Topics: Blood Glucose; Body Weight; Burns; Carbohydrate Metabolism; Catecholamines; Glucagon; Glucose; Glucose Tolerance Test; Homeostasis; Humans; Hyperglycemia; Insulin; Kinetics; Nitrogen; Wounds and Injuries | 1976 |
The hypothalamic regulatory hormones and their clinical applications.
Topics: Female; Follicle Stimulating Hormone; Gastrins; Glucagon; Gonadotropin-Releasing Hormone; Humans; Hyperglycemia; Hyperthyroidism; Hypothalamus; Hypothyroidism; Insulin; Luteinizing Hormone; Male; Menopause; Pituitary Gland, Anterior; Somatostatin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1976 |
Evolving role of glucagon in human diabetes mellitus.
Topics: Diabetes Mellitus; Glucagon; Glucose; Humans; Hyperglycemia; Insulin Antagonists; Insulin Resistance; Ketone Bodies; Liver | 1975 |
Regulation of net hepatic glucose uptake in vivo.
Topics: Administration, Oral; Animals; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Liver; Pancreatic Hormones; Portal Vein | 1992 |
Glucose counterregulation, hypoglycemia, and intensive insulin therapy in diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Islets of Langerhans; Liver; Neurotransmitter Agents | 1985 |
The relevance of glucose counterregulatory systems to patients with insulin-dependent diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Autonomic Nervous System Diseases; Blood Glucose; Brain; Chromaffin System; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Neuropathies; Epinephrine; Forecasting; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Stress, Physiological; Sympathetic Nervous System | 1986 |
[Hormonal disorders after radical operations on the pancreas (a review of the literature)].
Topics: Adaptation, Physiological; Blood Glucose; Diabetes Mellitus; Duodenum; Endocrine System Diseases; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Lipase; Pancreas; Pancreatectomy; Postoperative Complications; Time Factors | 1985 |
Is glucose intolerance harmful for the uremic patient?
Topics: Amino Acids, Branched-Chain; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Glomerular Filtration Rate; Glucagon; Glucose; Glycated Hemoglobin; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Lipoproteins, VLDL; Renal Dialysis; Uremia | 1985 |
Pancreatic glucagon in health and disease.
Topics: Amino Acids; Cyclic AMP; Diabetes Mellitus; Digestive System; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Glycogen; Humans; Hyperglycemia; Insulin; Insulin Secretion; Liver Glycogen; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms | 1971 |
Radioimmunoassay in gastroenterology.
Topics: Age Factors; Anemia, Pernicious; Antigen-Antibody Reactions; Antigens, Neoplasm; Cholecystokinin; Cross Reactions; Digestive System Physiological Phenomena; Duodenal Ulcer; Gastric Mucosa; Gastrins; Gastrointestinal Diseases; Gastrointestinal Hormones; Gastrointestinal Neoplasms; Glucagon; Hepatitis B Antigens; Hormones; Humans; Hyperglycemia; Insulin; Methods; Radioimmunoassay; Secretin; Zollinger-Ellison Syndrome | 1972 |
[Carbohydrate metabolism in liver diseases].
Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hepatitis; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Liver Cirrhosis; Liver Diseases; Pancreatitis; Tolbutamide | 1974 |
[Intensive medicine. Acute threatening metabolic disorders in diabetes mellitus].
Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Diagnosis, Differential; Electrolytes; Emergencies; Glucagon; Glucose; Glycosuria; Humans; Hyperglycemia; Hypoglycemia; Infusions, Parenteral; Insulin; Insulin Resistance; Lactates; Mental Disorders; Neurologic Manifestations; Osmosis; Prognosis; Shock | 1972 |
[Glucagon: recent physiological data].
Topics: Animals; Biological Assay; Cats; Cobalt; Coloring Agents; Diabetes Mellitus; Dogs; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucosyltransferases; Glycogen Storage Disease; Guinea Pigs; Humans; Hyperglycemia; Islets of Langerhans; Liver Glycogen; Mice; Proteins; Rabbits; Radioimmunoassay; Rats; Species Specificity; Water-Electrolyte Balance | 1968 |
Glucagon.
Topics: Animals; Calcium; Catecholamines; Dogs; Gastric Juice; Glucagon; Glucose; Humans; Hyperglycemia; Pancreas; Pancreatic Juice; Parathyroid Glands; Rabbits; Radioimmunoassay; Rats | 1969 |
[Glucagon mediated insulin release in man].
Topics: Blood Glucose; Diabetes Mellitus; Ethanol; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Liver Cirrhosis; Methandrostenolone; Obesity; Pancreas | 1968 |
[Growth hormone and carbohydrate metabolism].
Topics: Acromegaly; Animals; Carbohydrate Metabolism; Diabetes Mellitus; Dogs; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Hypopituitarism; Insulin; Pancreas; Phentolamine; Propranolol; Rats | 1971 |
The hypothalamus and metabolic control.
Topics: Adipose Tissue; Adrenal Glands; Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Dogs; Electroencephalography; Fatty Acids; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Hypothalamus; Insulin; Insulin Secretion; Lipid Metabolism; Metabolism; Obesity; Rats; Triglycerides; Vagus Nerve | 1971 |
88 trial(s) available for glucagon and Hyperglycemia
| Article | Year |
|---|---|
Beneficial effects of premeal almond load on glucose profile on oral glucose tolerance and continuous glucose monitoring: randomized crossover trials in Asian Indians with prediabetes.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Postprandial Period; Prediabetic State; Prunus dulcis | 2023 |
Effects of Dietary Fat and Protein on Glucoregulatory Hormones in Adolescents and Young Adults With Type 1 Diabetes.
Topics: Adult; Australia; Biomarkers; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Female; Follow-Up Studies; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Male; Meals; Prognosis | 2022 |
Pramlintide but Not Liraglutide Suppresses Meal-Stimulated Glucagon Responses in Type 1 Diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Islet Amyloid Polypeptide; Liraglutide; Male; Meals; Postprandial Period; Treatment Outcome; Young Adult | 2018 |
Effects on the glucagon response to hypoglycaemia during DPP-4 inhibition in elderly subjects with type 2 diabetes: A randomized, placebo-controlled study.
Topics: Aged; Aged, 80 and over; Aging; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Male; Meals; Metformin; Risk; Sitagliptin Phosphate; Sweden | 2018 |
Mechanisms of early glucose regulation disturbance after out-of-hospital cardiopulmonary resuscitation: An explorative prospective study.
Topics: Aged; Aged, 80 and over; Blood Glucose; Cardiopulmonary Resuscitation; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Prospective Studies | 2019 |
A randomised trial of enteric-coated nutrient pellets to stimulate gastrointestinal peptide release and lower glycaemia in type 2 diabetes.
Topics: Area Under Curve; Blood Glucose; Colon; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Ileum; Insulin; Lauric Acids; Male; Metformin; Middle Aged; Tablets, Enteric-Coated; Time Factors | 2013 |
Hyperglycemia associated with pasireotide: results from a mechanistic study in healthy volunteers.
Topics: Adolescent; Adult; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Male; Middle Aged; Somatostatin | 2013 |
Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass.
Topics: Adult; Blood Glucose; Female; Gastric Bypass; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Obesity, Morbid; Pancreas; Peptide Fragments; Postprandial Period; Treatment Outcome | 2013 |
Glucose-dependent insulinotropic polypeptide: blood glucose stabilizing effects in patients with type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Male; Middle Aged | 2014 |
Management of hyperglycemia associated with pasireotide (SOM230): healthy volunteer study.
Topics: Adamantane; Adolescent; Adult; Blood Glucose; Cyclohexanes; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Healthy Volunteers; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Liraglutide; Male; Maximum Tolerated Dose; Metformin; Middle Aged; Nateglinide; Nitriles; Phenylalanine; Prognosis; Pyrrolidines; Somatostatin; Vildagliptin; Young Adult | 2014 |
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.
Topics: Benzhydryl Compounds; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fasting; Glucagon; Glucose; Glucose Clamp Technique; Glucosides; Humans; Hyperglycemia; Insulin; Male; Metformin; Middle Aged; Muscles; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Time Factors | 2014 |
The acute effects of interval- Vs continuous-walking exercise on glycemic control in subjects with type 2 diabetes: a crossover, controlled study.
Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Exercise; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Oxygen Consumption; Walking | 2014 |
Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake.
Topics: Adult; Cross-Over Studies; Eating; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Male; Young Adult | 2014 |
Role of glucagon-like peptide-1 analogue versus amylin as an adjuvant therapy in type 1 diabetes in a closed loop setting with ePID algorithm.
Topics: Adolescent; Adult; Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Islet Amyloid Polypeptide; Male; Pancreas, Artificial; Peptides; Venoms; Young Adult | 2014 |
Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial.
Topics: Blood Glucose; C-Peptide; Carbohydrate Metabolism; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Double-Blind Method; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Isomaltose; Male; Middle Aged; Postprandial Period; Sucrose | 2014 |
Effects of dipeptidyl peptidase IV inhibition on glycemic, gut hormone, triglyceride, energy expenditure, and energy intake responses to fat in healthy males.
Topics: Adamantane; Adolescent; Adult; Appetite Regulation; Cross-Over Studies; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Energy Intake; Energy Metabolism; Food-Drug Interactions; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Insulin Secretion; Male; Middle Aged; Nitriles; Peptide Fragments; Peptide YY; Postprandial Period; Pyrrolidines; Vildagliptin; Young Adult | 2014 |
Albiglutide does not impair the counter-regulatory hormone response to hypoglycaemia: a randomized, double-blind, placebo-controlled, stepped glucose clamp study in subjects with type 2 diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Down-Regulation; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Middle Aged; Pancreas; Recombinant Proteins; Up-Regulation | 2015 |
Addition of sitagliptin or metformin to insulin monotherapy improves blood glucose control via different effects on insulin and glucagon secretion in hyperglycemic Japanese patients with type 2 diabetes.
Topics: Aged; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Resistance; Drug Therapy, Combination; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Postprandial Period; Sitagliptin Phosphate | 2015 |
Comparison of a carbohydrate-free diet vs. fasting on plasma glucose, insulin and glucagon in type 2 diabetes.
Topics: Aged; Blood Glucose; C-Peptide; Caloric Restriction; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet, Reducing; Fasting; Glucagon; Hospitals, Veterans; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Weight Loss | 2015 |
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients.
Topics: Adult; Aged; Blood Glucose; Eating; Female; Food; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Incretins; Insulin; Insulin Secretion; Male; Middle Aged; Postprandial Period; Time Factors; Young Adult | 2015 |
Effects of glucose-dependent insulinotropic polypeptide on gastric emptying, glycaemia and insulinaemia during critical illness: a prospective, double blind, randomised, crossover study.
Topics: Adult; Aged; Critical Illness; Cross-Over Studies; Double-Blind Method; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Prospective Studies | 2015 |
Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes.
Topics: Adult; Aged; Biphenyl Compounds; Cohort Studies; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucagon; Glycated Hemoglobin; Half-Life; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Molecular Targeted Therapy; Receptors, Glucagon; Risk; Single-Blind Method | 2015 |
A high-protein breakfast induces greater insulin and glucose-dependent insulinotropic peptide responses to a subsequent lunch meal in individuals with type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Breakfast; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet; Diet Records; Dietary Carbohydrates; Dietary Proteins; Energy Intake; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Lunch; Male; Middle Aged; Postprandial Period; Single-Blind Method; Young Adult | 2015 |
Comparison of appetite responses to high- and low-glycemic index postexercise meals under matched insulinemia and fiber in type 1 diabetes.
Topics: Adult; Appetite Regulation; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Diabetic; Dietary Fiber; Drug Therapy, Combination; Exercise; Glucagon; Glucagon-Like Peptide 1; Glycemic Index; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin Aspart; Insulin Glargine; Insulin, Long-Acting; Jogging; Male; Meals; Postprandial Period | 2015 |
Fasting until noon triggers increased postprandial hyperglycemia and impaired insulin response after lunch and dinner in individuals with type 2 diabetes: a randomized clinical trial.
Topics: Adult; Aged; Blood Glucose; Body Mass Index; Breakfast; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Follow-Up Studies; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Lunch; Male; Meals; Middle Aged; Postprandial Period | 2015 |
Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion.
Topics: Adult; Aged; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Fiber; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Intestinal Mucosa; Male; Middle Aged; ROC Curve | 2016 |
Performance and safety of an integrated bihormonal artificial pancreas for fully automated glucose control at home.
Topics: Adolescent; Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Home Care Services; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Infusion Systems; Insulins; Male; Middle Aged; Pancreas, Artificial; Pilot Projects; Treatment Outcome; Young Adult | 2016 |
Adjuvant Liraglutide and Insulin Versus Insulin Monotherapy in the Closed-Loop System in Type 1 Diabetes: A Randomized Open-Labeled Crossover Design Trial.
Topics: Adult; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Incidence; Insulin; Insulin Infusion Systems; Liraglutide; Male; Middle Aged; ROC Curve | 2016 |
Once-weekly dulaglutide 1.5 mg restores insulin secretion in response to intravenous glucose infusion.
Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Glucagon; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Infusions, Intravenous; Injections, Subcutaneous; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Recombinant Fusion Proteins; Treatment Outcome | 2017 |
Outpatient 60-hour day-and-night glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or sensor-augmented pump therapy in adults with type 1 diabetes: An open-label, randomised, crossover, controlled trial.
Topics: Activities of Daily Living; Adult; Blood Glucose; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus, Type 1; Glucagon; Glycated Hemoglobin; Hormone Replacement Therapy; Humans; Hyperglycemia; Hypoglycemia; Infusion Pumps; Insulin; Insulin Infusion Systems; Middle Aged; Monitoring, Ambulatory; Pancreas, Artificial; Patient Education as Topic; Quebec; Risk | 2017 |
Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans.
Topics: Adiponectin; Adult; Blood Glucose; Cross-Over Studies; Diet; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Male | 2008 |
Reducing postprandial hyperglycemia with adjuvant premeal pramlintide and postmeal insulin in children with type 1 diabetes mellitus.
Topics: Adolescent; Amyloid; Chemotherapy, Adjuvant; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Drug Administration Schedule; Feeding Behavior; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male | 2009 |
Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes.
Topics: Adamantane; Aged; Blood Glucose; Body Mass Index; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Middle Aged; Nitriles; Pyrrolidines; Vildagliptin | 2009 |
Twenty-four-hour simultaneous subcutaneous Basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia.
Topics: Adolescent; Amyloid; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucagon; Hormones; Humans; Hyperglycemia; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Islet Amyloid Polypeptide; Male; Postprandial Period; Young Adult | 2009 |
Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetes.
Topics: Area Under Curve; Blood Glucose; Cross-Over Studies; Cyclic AMP; Diabetes Mellitus, Type 2; Diet, Diabetic; Glucagon; Glutaminase; Humans; Hyperglycemia; Hypoglycemic Agents; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Metformin; Placebos; Postprandial Period; Sulfonylurea Compounds | 2009 |
The effect of exogenous glucagon-like peptide-1 on the glycaemic response to small intestinal nutrient in the critically ill: a randomised double-blind placebo-controlled cross over study.
Topics: Adult; Aged; Area Under Curve; Blood Glucose; Critical Illness; Cross-Over Studies; Double-Blind Method; Enteral Nutrition; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Incretins; Infusions, Intravenous; Insulin; Male; Middle Aged | 2009 |
Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction.
Topics: Adult; Amyloid; Area Under Curve; C-Peptide; Demography; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Middle Aged; Peptides; Primary Graft Dysfunction; Prospective Studies; Transplantation, Homologous; Venoms | 2009 |
Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans.
Topics: Animals; Anserine; Autonomic Nervous System; Blood Glucose; Cross-Over Studies; Deoxyglucose; Dose-Response Relationship, Drug; Drug Administration Routes; Glucagon; Glucose Tolerance Test; Histamine H3 Antagonists; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Neurons; Rats; Rats, Wistar; Sympatholytics; Time Factors; Vagus Nerve | 2010 |
Gastric emptying, incretin hormone secretion, and postprandial glycemia in cystic fibrosis--effects of pancreatic enzyme supplementation.
Topics: Adult; Blood Glucose; Cystic Fibrosis; Dietary Carbohydrates; Dietary Fats; Double-Blind Method; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Incretins; Insulin; Lipase; Male; Pancreas; Young Adult | 2011 |
Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients.
Topics: Administration, Oral; Aged; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glutamine; Humans; Hyperglycemia; Insulin; Insulin Secretion; Male; Middle Aged; Postprandial Period; Pyrazines; Sitagliptin Phosphate; Triazoles | 2011 |
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans.
Topics: Adult; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Injections, Intraventricular; Insulin; Insulin Secretion; Male; Young Adult | 2011 |
Does the fat-protein meal increase postprandial glucose level in type 1 diabetes patients on insulin pump: the conclusion of a randomized study.
Topics: Adolescent; Blood Glucose; Blood Glucose Self-Monitoring; C-Peptide; Child; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Postprandial Period | 2012 |
Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance.
Topics: Adult; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gastric Bypass; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Obesity, Morbid; Postprandial Period; Time Factors | 2012 |
Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes.
Topics: Adamantane; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glucagon; Glucagon-Secreting Cells; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nitriles; Pyrrolidines; Vildagliptin; Young Adult | 2012 |
Tighter control of postprandial hyperglycemia with mitiglinide/voglibose fixed-dose combination in Japanese patients with type 2 diabetes mellitus.
Topics: Aged; Asian People; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Inositol; Insulin; Isoindoles; Male; Middle Aged | 2012 |
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity.
Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Pancreatic Hormones | 2012 |
Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?
Topics: Adolescent; Adult; Anthropometry; Arginine; Blood Glucose; Dose-Response Relationship, Drug; Double-Blind Method; Glucagon; Glucocorticoids; Glucose Clamp Technique; Heart Rate; Humans; Hyperglycemia; Incretins; Islets of Langerhans; Male; Pancreatic Diseases; Pancreatic Function Tests; Prednisolone; Stimulation, Chemical; Sympathetic Nervous System; Vagus Nerve; Young Adult | 2013 |
Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia.
Topics: Adult; Calorimetry, Indirect; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Infusions, Intravenous; Male; Middle Aged | 2013 |
Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Resistance; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Incretins; Injections, Subcutaneous; Liraglutide; Male; Metformin; Middle Aged; Peptides | 2013 |
The human amylin analog, pramlintide, reduces postprandial hyperglucagonemia in patients with type 2 diabetes mellitus.
Topics: Adult; Amyloid; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male; Middle Aged; Postprandial Period | 2002 |
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Middle Aged; Neurotransmitter Agents; Nuclear Proteins; Pancreatitis; Peptide Fragments; Phenotype; Protein Precursors; Transcription Factors | 2003 |
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Parenteral Nutrition, Total; Peptide Fragments; Placebos | 2004 |
Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes.
Topics: Adult; Aged; Analysis of Variance; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Male; Middle Aged; Peptide Fragments; Postoperative Care; Postoperative Complications; Protein Precursors | 2004 |
The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes.
Topics: Adolescent; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male | 2005 |
Initially more rapid small intestinal glucose delivery increases plasma insulin, GIP, and GLP-1 but does not improve overall glycemia in healthy subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Insulin; Intestine, Small; Male; Peptide Fragments; Postprandial Period; Protein Precursors; Reference Values | 2005 |
Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight.
Topics: Adult; Blood Glucose; C-Peptide; Eating; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Infant, Low Birth Weight; Infant, Newborn; Insulin; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors | 2005 |
Effect of prior hyperglycemia on IL-6 responses to exercise in children with type 1 diabetes.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; Female; Glucagon; Glucose Clamp Technique; Growth Substances; Humans; Hydrocortisone; Hyperglycemia; Insulin; Interleukin-6; Male; Oxygen Consumption | 2006 |
Effects of hyperglycemia on glucose metabolism before and after oral glucose ingestion in normal men.
Topics: Administration, Oral; Blood Glucose; C-Peptide; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Time Factors | 2006 |
Diurnal rhythm in endogenous glucose production is a major contributor to fasting hyperglycaemia in type 2 diabetes. Suprachiasmatic deficit or limit cycle behaviour?
Topics: Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose; Homeostasis; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Nonlinear Dynamics; Suprachiasmatic Nucleus | 2006 |
Effect of pioglitazone on the metabolic and hormonal response to a mixed meal in type II diabetes.
Topics: Adiponectin; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Glycated Hemoglobin; Glycolysis; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Lactates; Male; Middle Aged; Pioglitazone; Thiazolidinediones | 2007 |
Postprandial hormonal responses to different types of complex carbohydrate in individuals with impaired glucose tolerance.
Topics: Adult; Aged; Blood Glucose; Cellulose; Dietary Carbohydrates; Edible Grain; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Starch; Vegetables | 1980 |
Comparison of serum glucose, insulin, and glucagon responses to different types of complex carbohydrate in noninsulin-dependent diabetic patients.
Topics: Adult; Aged; Blood Glucose; Bread; Diabetes Mellitus; Dietary Carbohydrates; Female; Glucagon; Glucose; Glycosuria; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Oryza; Vegetables; Zea mays | 1981 |
Regulation of insulin-like growth factor binding protein-1 (IGFBP-1) in insulin-dependent diabetes mellitus. Effects of hyperglycaemia and insulin.
Topics: Adult; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Insulin Antagonists; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Male | 1994 |
Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus.
Topics: Autonomic Nervous System; Diabetes Mellitus, Type 2; Eating; Female; Gastric Emptying; Gastrointestinal Motility; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver; Male; Middle Aged; Muscle Contraction; Stomach | 1995 |
Blood glucose estimation and symptoms during hyperglycemia and hypoglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Affect; Blood Glucose; Cluster Analysis; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Hormones; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Male; Norepinephrine; Surveys and Questionnaires | 1995 |
Effects of insulin and glucose on urea synthesis in normal man, independent of pancreatic hormone secretion.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Liver; Male; Nitrogen; Pancreas; Pancreatic Hormones; Somatostatin; Urea | 1994 |
beta-Endorphin and some hormonal levels in children with acute stress hyperglycaemia.
Topics: Acute Disease; beta-Endorphin; Blood Glucose; Bronchopneumonia; Child; Child, Preschool; Female; Gastroenteritis; Glucagon; Growth Hormone; Hormones; Humans; Hydrocortisone; Hyperglycemia; Infant; Insulin; Male; Prolactin; Sepsis; Stress, Physiological; Thyrotropin | 1994 |
Subcutaneous injection of the incretin hormone glucagon-like peptide 1 abolishes postprandial glycemia in NIDDM.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Injections, Subcutaneous; Insulin; Male; Middle Aged; Peptide Fragments; Protein Precursors; Radioimmunoassay; Time Factors | 1994 |
Acute hyperglycaemic effect of anaesthetic induction with thiopentone.
Topics: Acute Disease; Anesthesia, Intravenous; Blood Glucose; Epinephrine; Female; Glucagon; Humans; Hyperglycemia; Insulin; Labetalol; Neurosecretory Systems; Norepinephrine; Placebos; Thiopental | 1993 |
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Kinetics; Male; Middle Aged; Peptide Fragments; Time Factors | 1993 |
The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans.
Topics: Adult; Amino Acids; C-Peptide; Fatty Acids, Nonesterified; Gastrointestinal Agents; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Lactates; Lactic Acid; Liver; Male; Models, Biological | 1996 |
Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects.
Topics: Administration, Oral; Adolescent; Adult; C-Peptide; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Peptide Fragments; Peptides; Secretory Rate; Stimulation, Chemical | 1997 |
Beta cell response to oral glimepiride administration during and following a hyperglycaemic clamp in NIDDM patients.
Topics: Administration, Oral; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Middle Aged; Pharmaceutical Preparations; Proinsulin; Sulfonylurea Compounds | 1997 |
Effects of differing antecedent hypoglycemia on subsequent counterregulation in normal humans.
Topics: Adult; Blood Glucose; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male; Neurosecretory Systems; Norepinephrine; Pancreatic Polypeptide; Single-Blind Method; Time Factors | 1997 |
Regulation of glucose homeostasis in humans with denervated livers.
Topics: Adult; Biomarkers; Blood Glucose; C-Peptide; Central Nervous System; Denervation; Glucagon; Glucose Clamp Technique; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Resistance; Liver; Liver Transplantation; Middle Aged; Models, Biological; Somatostatin; Time Factors | 1997 |
Neuroendocrine stress hormones do not recreate the postoperative hypercoagulable state.
Topics: Adult; Angiotensin II; Blood Coagulation; Epinephrine; Female; Glucagon; Hemodynamics; Humans; Hydrocortisone; Hyperglycemia; Leukocyte Count; Male; Norepinephrine; Plasminogen Activator Inhibitor 1; Platelet Count; Postoperative Period; Protein C; Stress, Physiological; Time Factors; Tissue Plasminogen Activator; Vasopressins | 1998 |
Inhibitory effects of hyperglycaemia on fed jejunal motility: potential role of hyperinsulinaemia.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Drug Combinations; Gastrointestinal Motility; Gastrointestinal Transit; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Jejunum; Male; Pancreatic Polypeptide; Peptide Fragments; Perfusion; Phospholipids; Protein Precursors; Sorbitol | 1998 |
Stress hyperglycemia in minimally invasive surgery.
Topics: Cholecystectomy, Laparoscopic; Cholelithiasis; Digestive System Surgical Procedures; Female; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Minimally Invasive Surgical Procedures; Postoperative Period; Preoperative Care; Statistics, Nonparametric; Stress, Physiological | 1998 |
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2.
Topics: Appetite; Blood Glucose; Brain Chemistry; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Eating; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Male; Middle Aged; Obesity; Peptide Fragments; Protein Precursors; Satiation | 1999 |
Effect of hemipancreatectomy and of pancreatic diversion on the tolerance to a glucose load in humans.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Feedback; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperglycemia; Immunosuppression Therapy; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Pancreas Transplantation; Pancreatectomy | 2000 |
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Reproducibility of Results | 2000 |
Effects of fructose on hepatic glucose metabolism in humans.
Topics: Adult; Blood Glucose; Carbon Isotopes; Deuterium; Female; Fructose; Glucagon; Glucose; Glucose Clamp Technique; Glucose-6-Phosphate; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Liver; Male; Somatostatin; Uridine Diphosphate Glucose | 2000 |
Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus.
Topics: Aged; Blood Glucose; Deuterium; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Glycolysis; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Ketone Bodies; Male; Middle Aged; Tritium | 2001 |
Comparison of the suppressive effects of elevated plasma glucose and free fatty acid levels on glucagon secretion in normal and insulin-dependent diabetic subjects. Evidence for selective alpha-cell insensitivity to glucose in diabetes mellitus.
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Receptors, Drug | 1976 |
Metabolic effects of hyperglycemia and hyperinsulinemia on fate of intracellular glucose in NIDDM.
Topics: Blood Glucose; C-Peptide; Calorimetry; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Lipid Metabolism; Male; Middle Aged; Obesity; Oxidation-Reduction | 1990 |
Impairment of noninsulin-mediated glucose disposal in the elderly.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Animals; Blood Glucose; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Middle Aged; Somatostatin | 1989 |
Glucagon in acute ureteral colic. A randomized trial.
Topics: Adult; Colic; Glucagon; Glycosuria; Humans; Hyperglycemia; Infusions, Parenteral; Injections, Intravenous; Middle Aged; Nausea; Random Allocation; Ureteral Calculi | 1986 |
Stimulation of glucagon secretion by oral glucose.
Topics: Adult; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Immunoassay; Insulin | 1965 |
750 other study(ies) available for glucagon and Hyperglycemia
| Article | Year |
|---|---|
Mesenchymal stem cell-conditioned medium alleviates high fat-induced hyperglucagonemia via miR-181a-5p and its target PTEN/AKT signaling.
Topics: Animals; Base Sequence; Cell Line; Culture Media, Conditioned; Diet, High-Fat; Glucagon; Hyperglycemia; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; MicroRNAs; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Reproducibility of Results; Signal Transduction | 2021 |
Hyperglucagonemia in Pediatric Adiposity Associates With Cardiometabolic Risk Factors but Not Hyperglycemia.
Topics: Adiposity; Adolescent; Blood Glucose; Body Mass Index; Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Resistance; Overweight; Pediatric Obesity; Risk Factors; Young Adult | 2022 |
Loss of urotensin II receptor diminishes hyperglycemia and kidney injury in streptozotocin-treated mice.
Topics: Animals; Glucagon; Hyperglycemia; Kidney; Mice; Mice, Knockout; Receptors, G-Protein-Coupled; Streptozocin; Urotensins | 2022 |
Fasting or the short-term consumption of a ketogenic diet protects against antipsychotic-induced hyperglycaemia in mice.
Topics: 3-Hydroxybutyric Acid; Animals; Antipsychotic Agents; Blood Glucose; Diet, Ketogenic; Esters; Fasting; Glucagon; Hyperglycemia; Insulin; Ketone Bodies; Ketones; Mice; Olanzapine | 2022 |
Glucagon Test Is a Useful Predictor of Withdrawal From Insulin Therapy in Subjects With Type 2 Diabetes Mellitus.
Topics: C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Humans; Hyperglycemia; Insulin | 2022 |
SARS-CoV-2 Infection Causes Hyperglycemia in Cats.
Topics: Animals; Cats; COVID-19; Glucagon; Humans; Hyperglycemia; RNA, Viral; SARS-CoV-2 | 2022 |
Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin-Secreting Cells; Mice; Receptors, Glucagon | 2022 |
The role of pancreas to improve hyperglycemia in STZ-induced diabetic rats by thiamine disulfide.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Insulin; Male; Pancreas; Rats; Streptozocin; Thiamine | 2022 |
The relationship between insulin and glucagon concentrations in non-diabetic humans.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Humans; Hyperglycemia; Insulin; Middle Aged; Reproducibility of Results | 2022 |
Comparative Effects of Co-Ingesting Whey Protein and Glucose Alone and Combined on Blood Glucose, Plasma Insulin and Glucagon Concentrations in Younger and Older Men.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Insulin; Male; Postprandial Period; Whey Proteins | 2022 |
Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia.
Topics: Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperglycemia; Insulin; Insulin-Secreting Cells; Mice; Pancreatic Diseases; Streptozocin; Thioredoxins | 2022 |
Olfactory marker protein regulation of glucagon secretion in hyperglycemia.
Topics: Animals; Glucagon; Humans; Hyperglycemia; Mice; Olfactory Marker Protein; Receptors, Odorant; RNA, Small Interfering; Streptozocin | 2022 |
Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules.
Topics: Blood Glucose; Boron Compounds; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin Resistance; Lipid Droplets | 2022 |
Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Type 2; Gene Expression; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Mice; RNA-Binding Proteins; src-Family Kinases; Transcription Factors | 2022 |
Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Topics: Alanine Transaminase; Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucagon; Hyperglycemia; Hypoglycemia; Insulin; Liver; Mice; Rats; Receptors, Glucagon; Streptozocin | 2023 |
Aspirin Suppresses Hepatic Glucagon Signaling Through Decreasing Production of Thromboxane A2.
Topics: Aspirin; Diabetes Mellitus; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Liver; Thromboxane A2 | 2023 |
Glucagon 100 years. Important, but still enigmatic.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Insulin | 2023 |
Chronic physiologic hyperglycemia impairs insulin-mediated suppression of plasma glucagon concentration in healthy humans.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance | 2023 |
Upregulated TGF-β1 contributes to hyperglycaemia in type 2 diabetes by potentiating glucagon signalling.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Type 2; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Humans; Hyperglycemia; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Transforming Growth Factor beta1 | 2023 |
Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia.
Topics: Animals; Glucagon; Glucose; Glutaminase; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Knockout; Tumor Suppressor Protein p53 | 2023 |
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Topics: Adult; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Mammals; Mechanistic Target of Rapamycin Complex 1 | 2023 |
Oleanolic acid and moderate drinking increase the pancreatic GLP-1R expression of the
Topics: Animals; Blood Glucose; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Hyperglycemia; Insulin; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2023 |
Peroxisomal ERK mediates Akh/glucagon action and glycemic control.
Topics: Animals; Carbohydrates; Drosophila; Drosophila Proteins; Extracellular Signal-Regulated MAP Kinases; Glucagon; Glycemic Control; Hyperglycemia; Peroxisomes | 2023 |
Obesity dysregulates fasting-induced changes in glucagon secretion.
Topics: Adult; Animals; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Male; Mice, Inbred C57BL; Middle Aged; Obesity; Pancreas | 2019 |
Mathematical modeling of the glucagon challenge test.
Topics: Blood Glucose; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Models, Theoretical; Receptors, Glucagon | 2019 |
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Gene Knockdown Techniques; Glucagon; Gluconeogenesis; Glucose; Glucose Intolerance; Hyperglycemia; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ubiquitin Thiolesterase | 2019 |
Berberine Attenuates Hyperglycemia by Inhibiting the Hepatic Glucagon Pathway in Diabetic Mice.
Topics: Animals; Berberine; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Liver; Mice; Mice, Obese; Signal Transduction | 2020 |
Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes.
Topics: Diabetes Mellitus, Type 2; Exocytosis; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Hyperglycemia; Insulin; Optical Imaging; Receptors, Somatostatin; Somatostatin | 2020 |
Novel Insights Into Effects of Cortisol and Glucagon on Nocturnal Glucose Production in Type 2 Diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Gluconeogenesis; Humans; Hydrocortisone; Hyperglycemia; Male; Middle Aged; Time Factors | 2020 |
A Protein/Lipid Preload Attenuates Glucose-Induced Endothelial Dysfunction in Individuals with Abnormal Glucose Tolerance.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Proteins; Endothelium, Vascular; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Postprandial Period; Young Adult | 2020 |
Rational design of a GLP-1/GIP/Gcg receptor triagonist to correct hyperglycemia, obesity and diabetic nephropathy in rodent animals.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Design; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide-1 Receptor; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity | 2020 |
A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control.
Topics: Animals; Cells, Cultured; Gain of Function Mutation; Glucagon; Gluconeogenesis; Glucose; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Isoforms; Protein-Arginine N-Methyltransferases | 2020 |
Impact of glucagon response on early postprandial glucose excursions irrespective of residual β-cell function in type 1 diabetes: A cross-sectional study using a mixed meal tolerance test.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin-Secreting Cells; Male; Meals; Middle Aged; Prospective Studies | 2021 |
Oxidized Pork Induces Disorders of Glucose Metabolism in Mice.
Topics: Animals; Blood Glucose; Body Weight; Cooking; Eating; Glucagon; Glucose; Glucose Metabolism Disorders; Glucose Tolerance Test; Hyperglycemia; Inflammation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Pork Meat | 2021 |
Targeting the glucagon receptor signaling pathway as a novel strategy to counteract PI3K inhibitor induced hyperglycemia while sustaining tumor PI3K inhibition.
Topics: Glucagon; Humans; Hyperglycemia; Neoplasms; Phosphatidylinositol 3-Kinases; Receptors, Glucagon; Signal Transduction | 2021 |
Acute pancreatitis-induced islet dysfunction in ferrets.
Topics: Acute Disease; Amylases; Animals; Blood Glucose; Ceruletide; Ferrets; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Insulin Resistance; Interleukin-6; Lipase; Pancreatitis; Tumor Necrosis Factor-alpha | 2021 |
Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Electromagnetic Fields; Energy Metabolism; Fasting; Glucagon; Hyperglycemia; Insulin; Lactic Acid; Lipids; Metabolomics; Oxidation-Reduction; Pyruvic Acid; Rats | 2021 |
Sam68 promotes hepatic gluconeogenesis via CRTC2.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blood Glucose; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA-Binding Proteins; Transcription Factors; Up-Regulation | 2021 |
Whey protein preload enhances the active GLP-1 response and reduces circulating glucose in women with polycystic ovarian syndrome.
Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Proteins; Dietary Supplements; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Hyperglycemia; Incretins; Insulin; Polycystic Ovary Syndrome; Postprandial Period; Whey Proteins; Young Adult | 2021 |
Synthesis and anti-diabetic activity of novel biphenylsulfonamides as glucagon receptor antagonists.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Mice, Inbred C57BL; Molecular Structure; Receptors, Glucagon; Structure-Activity Relationship; Sulfonamides | 2021 |
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Glucagon; Hyperglycemia; Lacticaseibacillus rhamnosus; Mice; Signal Transduction | 2021 |
O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
Topics: Acetylglucosamine; Animals; Base Sequence; Caloric Restriction; Cell Line; Colforsin; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Glucocorticoids; Gluconeogenesis; Glucose; Glycosylation; Hepatocytes; Humans; Hydrocortisone; Hyperglycemia; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Protein Binding; Protein Stability; Pyruvic Acid; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53 | 2021 |
The effect of PPARγ agonist on SGLT2 and glucagon expressions in alpha cells under hyperglycemia.
Topics: Animals; Cells, Cultured; Chromans; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperglycemia; Hypoglycemic Agents; Mice; Phosphatidylinositol 3-Kinases; PPAR gamma; Proto-Oncogene Proteins c-akt; Signal Transduction; Sodium-Glucose Transporter 2; Thiazolidinediones; Troglitazone | 2017 |
Glucagon receptor knockout mice are protected against acute olanzapine-induced hyperglycemia.
Topics: Animals; Benzodiazepines; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glucose Tolerance Test; Homeostasis; Hyperglycemia; Insulin; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Olanzapine; Receptors, Glucagon | 2017 |
Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.
Topics: Animals; Blood Glucose; Body Weight; Cyclic AMP; Disease Models, Animal; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Glucagon; Heart; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin-Like Growth Factor I; Ki-67 Antigen; Kidney; Liver; Male; Octreotide; Phosphoproteins; Polycystic Kidney, Autosomal Recessive; Rats; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases; Somatostatin | 2017 |
Recycling of glucagon receptor to plasma membrane increases in adipocytes of obese rats by soy protein; implications for glucagon resistance.
Topics: Adipocytes; Adipose Tissue, White; Animals; Cell Membrane; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Gene Expression Regulation; Glucagon; Hyperglycemia; Male; Obesity; rab GTP-Binding Proteins; Rats; Rats, Zucker; Receptors, Glucagon; Soybean Proteins; Triglycerides | 2017 |
Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1.
Topics: Adenoma; Animals; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus, Type 2; Forkhead Box Protein O1; Glucagon; Glucagon-Secreting Cells; Glucose; Hydrogen Peroxide; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Mice; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt | 2017 |
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Like Peptide 1; HEK293 Cells; Humans; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Obese; Receptors, Glucagon | 2017 |
Transplantation of stromal-derived factor 1α and basic fibroblast growth factor primed insulin-producing cells reverses hyperglycaemia in diabetic rats.
Topics: Animals; Blood Glucose; Cells, Cultured; Chemokine CXCL12; Diabetes Mellitus, Experimental; Female; Fibroblast Growth Factors; Glucagon; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Rats; Rats, Sprague-Dawley | 2017 |
Rebirth of the Incretin Concept: Its conception and early development.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Incretins; Insulin; Peptide Fragments | 2018 |
Suppression of Extrapancreatic Glucagon by Octreotide May Reduce the Fasting and Postprandial Glucose Levels in a Diabetic Patient after Total Pancreatectomy.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Middle Aged; Octreotide; Pancreatectomy; Postprandial Period | 2017 |
Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucagon; Homeostasis; Hyperglycemia; Insulin; Leptin; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Receptors, Glucagon; RNA, Small Interfering | 2017 |
Impaired Insulin Action Is Associated With Increased Glucagon Concentrations in Nondiabetic Humans.
Topics: Biomarkers; Blood Glucose; C-Peptide; Cross-Sectional Studies; Female; Follow-Up Studies; Glucagon; Glucagon-Secreting Cells; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Prediabetic State; Prognosis | 2018 |
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.
Topics: Alloxan; Animals; Blood Glucose; Cellular Reprogramming; Dependovirus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression Profiling; Genetic Therapy; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Lectins, C-Type; Mice, Inbred C57BL; Mice, SCID; Receptors, Immunologic; Trans-Activators | 2018 |
Glucagon receptor signalling - backwards and forwards.
Topics: Animals; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Receptors, Glucagon; Signal Transduction | 2018 |
Additional dexamethasone in chemotherapies with carboplatin and paclitaxel could reduce the impaired glycometabolism in rat models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carboplatin; Dexamethasone; Disease Models, Animal; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ovarian Neoplasms; Paclitaxel; Rats | 2018 |
Targeting hepatic glutaminase activity to ameliorate hyperglycemia.
Topics: Animals; Cells, Cultured; Cryopreservation; Glucagon; Glutaminase; Glutamine; Hepatocytes; Humans; Hyperglycemia; Kinetics; Liver; Metabolic Flux Analysis; Mice, Inbred C57BL; Mice, Knockout | 2018 |
Acute effects of glucagon on the liver.
Topics: Glucagon; Glutaminase; Humans; Hyperglycemia; Insulin; Liver | 2018 |
Effectiveness of bioengineered islet cell sheets for the treatment of diabetes mellitus.
Topics: Abdominal Cavity; Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; DNA Methylation; Glucagon; Homeodomain Proteins; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, SCID; Nerve Tissue Proteins; Primary Cell Culture; Promoter Regions, Genetic; Streptozocin; Tissue Engineering; Trans-Activators; Treatment Outcome | 2018 |
Association between serum somatostatin levels and glucose-lipid metabolism in the Jino ethnic minority and Han Chinese population.
Topics: Adult; Asian People; C-Peptide; China; Cholesterol, HDL; Fasting; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Lipid Metabolism; Middle Aged; Somatostatin | 2018 |
Clozapine-Induced Acute Hyperglycemia Is Accompanied with Elevated Serum Concentrations of Adrenaline and Glucagon in Rats.
Topics: Animals; Antipsychotic Agents; Blood Glucose; Clozapine; Corticosterone; Epinephrine; Glucagon; Hyperglycemia; Insulin; Male; Rats, Wistar | 2018 |
Metabolic Fate of the Glucose Taken up by the Intestine During Induced Hyperglycaemia in Dogs.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Gluconeogenesis; Glucose; Glycogen; Hyperglycemia; Insulin; Intestinal Mucosa; Male | 2018 |
Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide-1 Receptor; Hyperglycemia; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Knockout; Receptors, Glucagon; Streptozocin; Transcriptome | 2018 |
Effects of Exendin-4 on pancreatic islets function in treating hyperglycemia post severe scald injury in rats.
Topics: Animals; Burns; Exenatide; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Islets of Langerhans; Rats; Rats, Wistar | 2018 |
SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice.
Topics: Anilides; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Hyperplasia; Insulin; Male; Mice; Sirtuin 1; Thiazoles | 2018 |
Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.
Topics: Adenosine Triphosphate; Animals; Cell Line; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Potassium Channels; Rats; Rats, Wistar; Sodium | 2019 |
Acute pancreatic beta cell apoptosis by IL-1β is responsible for postburn hyperglycemia: Evidence from humans and mice.
Topics: Acute Disease; Adult; Animals; Apoptosis; Blood Glucose; Burns; Disease Models, Animal; Female; Glucagon; Glucocorticoids; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Interleukin-1beta; Male; Mice, Inbred C57BL; Models, Biological; Neutralization Tests; Survival Analysis | 2019 |
Investigation of the diabetic effects of maternal high-glucose diet on rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes, Gestational; Female; Glucagon; Glucose; Hyperglycemia; Pancreas; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2019 |
Sodium transport in diabetes: two sides to the coin.
Topics: Adenosine Triphosphate; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Sodium | 2019 |
Intranasal glucagon acutely increases energy expenditure without inducing hyperglycaemia in overweight/obese adults.
Topics: Administration, Intranasal; Blood Glucose; Cross-Over Studies; Eating; Energy Metabolism; Female; Glucagon; Humans; Hyperglycemia; Male; Middle Aged; Obesity; Overweight | 2019 |
Mild Physiologic Hyperglycemia Induces Hepatic Insulin Resistance in Healthy Normal Glucose-Tolerant Participants.
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycogenolysis; Healthy Volunteers; Humans; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Middle Aged; Tritium | 2019 |
Glucose and amino acid metabolism in mice depend mutually on glucagon and insulin receptor signaling.
Topics: Amino Acids; Animals; Blood Glucose; Glucagon; Glucose; Hyperglycemia; Hyperinsulinism; Mice; Peptides; Receptor, Insulin; Receptors, Glucagon | 2019 |
Optimal regulation of blood glucose level in Type I diabetes using insulin and glucagon.
Topics: Algorithms; Blood Glucose; Diabetes Mellitus, Type 1; Drug Delivery Systems; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Nonlinear Dynamics; Postprandial Period; Risk | 2019 |
Temporal analysis of distribution pattern of islet cells and antioxidant enzymes for diabetes onset in postnatal critical development window in rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Pancreas; Pregnancy; Rats; Rats, Wistar; Spatio-Temporal Analysis; Streptozocin | 2019 |
Glucose-dependent Insulinotropic Polypeptide (GIP) Resistance and β-cell Dysfunction Contribute to Hyperglycaemia in Acromegaly.
Topics: Acromegaly; Adult; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Incretins; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Prospective Studies; Receptors, Gastrointestinal Hormone | 2019 |
Oxygen dependence of glucose sensing: role in glucose homeostasis and related pathology.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucokinase; Glucose; Homeostasis; Humans; Hyperglycemia; Insulin; Oxidative Phosphorylation; Oxygen; Pancreas; Regional Blood Flow; Vascular Diseases | 2019 |
Intra-islet glucagon signaling is critical for maintaining glucose homeostasis.
Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Transgenic; Paracrine Communication; Receptors, G-Protein-Coupled; Signal Transduction | 2019 |
Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes.
Topics: Animals; B7-1 Antigen; Cell Proliferation; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucagon-Secreting Cells; Homeodomain Proteins; Hyperglycemia; Insulin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Trans-Activators | 2019 |
desHis¹Glu⁹-glucagon-[mPEG] and desHis¹Glu⁹(Lys³⁰PAL)-glucagon: long-acting peptide-based PEGylated and acylated glucagon receptor antagonists with potential antidiabetic activity.
Topics: Acylation; Animals; Cell Line; Cyclic AMP; Dipeptidyl Peptidase 4; Drug Stability; Glucagon; HEK293 Cells; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Obese; Obesity; Polyethylene Glycols; Receptors, Glucagon; Recombinant Proteins; Second Messenger Systems | 2013 |
Evaluation of liver glycogen catabolism during hypercortisolism induced by the administration of dexamethasone in rats.
Topics: Animals; Body Weight; Cushing Syndrome; Cyclic AMP; Dexamethasone; Epinephrine; Fasting; Glucagon; Glucose Intolerance; Glycogen; Hyperglycemia; Liver; Male; Rats; Rats, Wistar | 2013 |
Chronic treatment with the AMP-kinase activator AICAR increases glycogen storage and fatty acid oxidation in skeletal muscles but does not reduce hyperglucagonemia and hyperglycemia in insulin deficient rats.
Topics: Adenylate Kinase; Adiposity; Aminoimidazole Carboxamide; Animals; Blood Glucose; Epididymis; Fatty Acids; Glucagon; Glycogen; Glycogen Synthase; Glycogen Synthase Kinase 3; Hyperglycemia; Insulin; Male; Muscle, Skeletal; Oxidation-Reduction; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribonucleotides; Triglycerides | 2013 |
Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion.
Topics: ADAM Proteins; ADAM17 Protein; Albuminuria; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Kidney Diseases; Male; Membrane Proteins; Mice; Peptidyl-Dipeptidase A; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-3; Triglycerides | 2013 |
Multiple intravenous infusions of bone marrow mesenchymal stem cells reverse hyperglycemia in experimental type 2 diabetes rats.
Topics: Administration, Intravenous; Animals; Blood Glucose; Bone Marrow; C-Peptide; Culture Media, Conditioned; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Streptozocin | 2013 |
Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia.
Topics: Animals; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Secreting Cells; Gluconeogenesis; Hyperglycemia; Hypoglycemic Agents; Infusions, Intraventricular; Injections, Intraventricular; Leptin; Liver; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Receptors, Leptin; Recombinant Proteins; Signal Transduction; Ventromedial Hypothalamic Nucleus | 2013 |
Sitagliptin improves postprandial hyperglycemia by inhibiting glucagon secretion in Werner syndrome with diabetes.
Topics: Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles; Werner Syndrome | 2013 |
Islet transplantation and insulin administration relieve long-term complications and rescue the residual endogenous pancreatic β cells.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Complications; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Neural Conduction; Nociception; Pain Threshold; Proteinuria; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2013 |
Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.
Topics: Animals; Appetite Depressants; Body Weight; Dietary Fats; Dietary Sucrose; Drug Resistance; Energy Metabolism; Feeding Behavior; Female; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hyperinsulinism; Hyperphagia; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Mice, Knockout; Neurons; Obesity; Pro-Opiomelanocortin; Receptor, Serotonin, 5-HT2C; Recombinant Fusion Proteins; Serotonin; Serotonin Receptor Agonists | 2013 |
The glycemic/metabolic responses to meal tolerance tests at breakfast, lunch and dinner, and effects of the mitiglinide/voglibose fixed-dose combination on postprandial profiles in Japanese patients with type 2 diabetes mellitus.
Topics: Aged; Blood Glucose; Breakfast; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Acids, Nonesterified; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemic Agents; Inositol; Insulin; Isoindoles; Lunch; Male; Meals; Middle Aged; Postprandial Period; Triglycerides | 2014 |
Variations in blood glucose levels following gastrostomy tube insertion in a paediatric population.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Female; Gastrointestinal Agents; Gastrostomy; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Infant; Infant, Newborn; Intubation, Gastrointestinal; Logistic Models; Male; Retrospective Studies | 2014 |
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Topics: Animals; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Eating; Glucagon; Glucokinase; Glucose; Glucose Clamp Technique; Glucosides; Hyperglycemia; Hyperinsulinism; Immunohistochemistry; Liver; Male; Obesity; Organ Size; Oxygen Consumption; Rats; Rats, Zucker; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2014 |
Alogliptin improves steroid-induced hyperglycemia in treatment-naïve Japanese patients with chronic kidney disease by decrease of plasma glucagon levels.
Topics: Aged; Asian People; Body Mass Index; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Japan; Kidney Function Tests; Male; Piperidines; Regression Analysis; Renal Insufficiency, Chronic; Steroids; Uracil; Vital Signs | 2014 |
Closed-loop artificial pancreas systems: physiological input to enhance next-generation devices.
Topics: Algorithms; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Eating; Exercise; Glucagon; Gonadal Steroid Hormones; Humans; Hyperglycemia; Hypoglycemia; Insulin; Insulin Infusion Systems; Pancreas, Artificial; Stress, Psychological | 2014 |
Effects of delayed gastric emptying on postprandial glucose kinetics, insulin sensitivity, and β-cell function.
Topics: Adolescent; Adult; Algorithms; Blood Glucose; C-Peptide; Female; Food; Gastric Emptying; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Kinetics; Male; Middle Aged; Young Adult | 2014 |
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
Topics: AMP-Activated Protein Kinases; Animals; Fasting; Gene Expression Regulation; Glucagon; Gluconeogenesis; Glucose; Hepatocytes; Hyperglycemia; Insulin; Liver; Male; Mice; Mice, Knockout; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Signal Transduction; Transcription Factors | 2014 |
PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin Resistance; Insulin-Secreting Cells; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; RNA, Small Interfering; Signal Transduction | 2015 |
Novel antidiabetic nutrients identified by in vivo screening for gastric secretion and emptying regulation in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Food; Gastric Emptying; Glucagon; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Postprandial Period; Rats, Wistar | 2014 |
Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells.
Topics: Animals; Blood Glucose; Body Temperature; Body Weight; Cell Line; Ceramides; Cricetinae; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Feeding Behavior; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Hyperinsulinism; Insulin; Insulin-Secreting Cells; Lipogenesis; Male; Mice, Inbred C57BL; Rats; Receptors, Glucagon; RNA, Messenger | 2014 |
Arginine is preferred to glucagon for stimulation testing of β-cell function.
Topics: Adult; Aged; Arginine; Blood Glucose; Body Mass Index; C-Peptide; Female; Glucagon; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Insulin-Secreting Cells; Kinetics; Male; Middle Aged; Mouth Mucosa; Nausea; Obesity; Paresthesia; Reproducibility of Results | 2014 |
Meal feeding improves oral glucose tolerance in male rats and causes adaptations in postprandial islet hormone secretion that are independent of plasma incretins or glycemia.
Topics: Allostasis; Animals; Behavior, Animal; Feeding Behavior; Gastric Inhibitory Polypeptide; Glucagon; Glucose Intolerance; Hyperglycemia; Ileum; Incretins; Insulin; Insulin Secretion; Intestinal Mucosa; Islets of Langerhans; Jejunum; Male; Meals; Neurosecretory Systems; Organ Specificity; Postprandial Period; Proglucagon; Rats, Long-Evans | 2014 |
Glucagon-induced angiogenesis and tumor growth through the HIF-1-VEGF-dependent pathway in hyperglycemic nude mice.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glucagon; Heterografts; Humans; Hyperglycemia; Hypoxia-Inducible Factor 1; Mice; Mice, Nude; Mice, Obese; Neoplasms; Neovascularization, Pathologic; Signal Transduction; Tumor Burden; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2014 |
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Topics: Animals; Animals, Newborn; Blood Glucose; Cell Proliferation; Diabetes, Gestational; Disease Models, Animal; Female; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Leptin; Mice; Organ Size; Phenotype; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Weight Gain | 2014 |
Teneligliptin improves glycemic control with the reduction of postprandial insulin requirement in Japanese diabetic patients.
Topics: Aged; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Japan; Middle Aged; Monitoring, Ambulatory; Postprandial Period; Pyrazoles; Thiazolidines | 2015 |
Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Exercise; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Injections; Insulin; Insulin Secretion; Male; Pancreas; Treatment Outcome | 2015 |
[The physiology of glucagon-like peptide-1 and its role in the pathophysiology of type 2 diabetes mellitus].
Topics: Animals; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Eating; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Homeostasis; Humans; Hyperglycemia; Incretins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Malabsorption Syndromes; Mice; Mice, Knockout; Models, Biological; Obesity; Receptors, Glucagon | 2014 |
Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.
Topics: Animals; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Retinoic Acid 4-Hydroxylase; Retinoids; Retinol-Binding Proteins, Cellular; Signal Transduction; Vitamin A Deficiency | 2015 |
Protein and glucose metabolic responses to hyperinsulinemia, hyperglycemia, and hyperaminoacidemia in obese men.
Topics: Adult; Amino Acids; Glucagon; Glucose; Human Growth Hormone; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Intravenous; Insulin; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Obesity; Octreotide; Pancreas; Postprandial Period; Young Adult | 2015 |
Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp.
Topics: Administration, Intravenous; Animals; Blood Glucose; Catheterization, Peripheral; Glucagon; Glucose Clamp Technique; Hyperglycemia; Insulin; Male; Portal Vein; Rats; Rats, Sprague-Dawley | 2015 |
The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes.
Topics: Adolescent; Age of Onset; Biomarkers; Blood Glucose; Child; Denmark; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin-Secreting Cells; Male; Multivariate Analysis; Prospective Studies; Time Factors | 2015 |
Pharmacokinetics and pharmacodynamics of the glucagon-like peptide-1 analog liraglutide in healthy cats.
Topics: Animals; Appetite; Blood Glucose; Cats; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Hyperglycemia; Hypoglycemic Agents; Insulin; Liraglutide; Male; Weight Loss | 2015 |
Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.
Topics: Animals; Diabetes Mellitus, Experimental; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; Insulin; Ketone Bodies; Ketosis; Liraglutide; Liver; Male; Rats, Wistar; Receptors, Glucagon; Streptozocin | 2015 |
The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model.
Topics: Animals; Apoptosis; Blood Glucose; C-Peptide; Cell Count; Diabetes Mellitus, Experimental; Exenatide; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Graft Survival; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice, Inbred BALB C; Models, Animal; Peptides; Venoms | 2015 |
Improvement of glycemic control in streptozotocin-induced diabetic rats by Atlantic salmon skin gelatin hydrolysate as the dipeptidyl-peptidase IV inhibitor.
Topics: Animals; British Columbia; Diabetes Mellitus, Type 2; Dietary Supplements; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Endopeptidases; Fish Proteins; Food-Processing Industry; Gelatin; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Industrial Waste; Insulin; Insulin Secretion; Male; Protein Hydrolysates; Rats, Sprague-Dawley; Salmo salar; Skin | 2015 |
Relationship between circadian blood pressure variability and function of islet α and β cell in type 2 diabetes with dyssomnia.
Topics: Administration, Oral; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diabetes Mellitus, Type 2; Dyssomnias; Female; Glucagon; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Prehypertension; Retrospective Studies | 2015 |
Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.
Topics: Animals; Diabetes Mellitus, Type 1; Down-Regulation; Electric Stimulation; Ganglia, Sympathetic; Ganglionic Stimulants; Glucagon; Hyperglycemia; Islets of Langerhans; Male; Mutant Proteins; Nerve Tissue Proteins; Neurons; Nicotinic Agonists; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Rats, Transgenic; Rats, Wistar; Receptors, Nicotinic; Synaptic Transmission; Wallerian Degeneration | 2015 |
Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Type 1; Dogs; Female; Glucagon; Hyperglycemia; Insulin; Insulin-Secreting Cells; Ketosis; Lymphocytes; Male; Organ Size | 2015 |
Effects of central gastrin-releasing peptide on glucose metabolism.
Topics: Analysis of Variance; Animals; Blood Glucose; Corticosterone; Gastrin-Releasing Peptide; Gastrointestinal Agents; Glucagon; Humans; Hyperglycemia; Injections, Intraventricular; Insulin; Male; Rats; Rats, Wistar; Time Factors | 2015 |
Prediabetes linked to excess glucagon in transgenic mice with pancreatic active AKT1.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Enzyme Activation; Fasting; Genotype; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Myristic Acids; Pancreas; Prediabetic State; Proto-Oncogene Proteins c-akt | 2016 |
β-Cell Glucose Sensitivity Is Linked to Insulin/Glucagon Bihormonal Cells in Nondiabetic Humans.
Topics: Adult; Aged; Female; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Middle Aged; Pancreas; Pancreatic Ducts; Pancreatic Function Tests; Pancreaticoduodenectomy | 2016 |
Pancreatic glucose-dependent insulinotropic polypeptide (GIP) (1-30) expression is upregulated in diabetes and PEGylated GIP(1-30) can suppress the progression of low-dose-STZ-induced hyperglycaemia in mice.
Topics: Animals; Body Weight; Cell Proliferation; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Gastric Inhibitory Polypeptide; Glucagon; Hyperglycemia; Hypoglycemic Agents; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Streptozocin | 2016 |
Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Acids; Glucagon; Glycerol; Hyperglycemia; Hypoglycemia; Insulin; Leptin; Mice; Mice, Knockout; Peptides; Receptor, Insulin; Triglycerides | 2016 |
Coping with an exogenous glucose overload: glucose kinetics of rainbow trout during graded swimming.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Female; Glucagon; Glucose; Glycogen; Hyperglycemia; Liver; Male; Oncorhynchus mykiss; Oxidation-Reduction; Oxygen Consumption; Physical Exertion; Swimming | 2016 |
Dulaglutide (LY-2189265) for the treatment of type 2 diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Humans; Hyperglycemia; Hypoglycemic Agents; Immunoglobulin Fc Fragments; Insulin; Insulin Secretion; Recombinant Fusion Proteins | 2016 |
HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Glucagon; Gluconeogenesis; Hepatocytes; Hyperglycemia; Insulin; Liver; Mice, Inbred C57BL; Mice, Transgenic; Postprandial Period; Primary Cell Culture; Signal Transduction; Von Hippel-Lindau Tumor Suppressor Protein | 2016 |
A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
Topics: Animals; Blood Glucose; Cystic Fibrosis; Cytokines; Female; Ferrets; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Male; Pancreas | 2016 |
MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk.
Topics: Animals; Apoptosis; Cell Survival; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Intolerance; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Iron-Binding Proteins; Membrane Proteins; Mice; Mitochondria; Receptor Cross-Talk; Ubiquitin-Protein Ligases | 2016 |
Mechanism Underlying Induction of Hyperglycemia in Rats by Single Administration of Olanzapine.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Corticosterone; Epinephrine; Glucagon; Histamine; Hyperglycemia; Injections, Intravenous; Insulin; Male; Models, Biological; Olanzapine; Propranolol; Rats, Wistar | 2016 |
Dogfish glucagon analogues counter hyperglycaemia and enhance both insulin secretion and action in diet-induced obese diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Dogfish; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Obese; Obesity | 2016 |
Cocaine- and amphetamine-regulated transcript: a novel regulator of energy homeostasis expressed in a subpopulation of pancreatic islet cells.
Topics: Animals; Brain; Diabetes Mellitus, Type 2; Glucagon; Homeostasis; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Nerve Tissue Proteins | 2016 |
Male Men1 heterozygous mice exhibit fasting hyperglycemia in the early stage of MEN1.
Topics: Animals; Fasting; Glucagon; Gluconeogenesis; Heterozygote; Hyperglycemia; Insulin Resistance; Islets of Langerhans; Liver; Male; Mice; Mice, Mutant Strains; Multiple Endocrine Neoplasia Type 1 | 2016 |
Role of Dual-Hormone Closed-Loop Delivery System in the Future.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Drug Monitoring; Drug Therapy, Combination; Glucagon; Hormone Replacement Therapy; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Infusion Pumps; Insulin; Insulin Infusion Systems; Monitoring, Ambulatory; Randomized Controlled Trials as Topic | 2016 |
Functional and Molecular Adaptations of Enteroendocrine L-Cells in Male Obese Mice Are Associated With Preservation of Pancreatic α-Cell Function and Prevention of Hyperglycemia.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Enteroendocrine Cells; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Hyperglycemia; Insulin-Secreting Cells; Male; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Peptide Fragments; Phenotype | 2016 |
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Drug Synergism; Glucagon; Hyperglycemia; Liver; Metabolic Diseases; Mice; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Obesity; Triiodothyronine | 2016 |
Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Fibroblast Growth Factors; Glucagon; Glucagon-Like Peptide 1; Glucuronidase; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Streptozocin | 2017 |
Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin-Secreting Cells; Ketosis; Mice; Mutation; Peptides; Receptor, Insulin; Receptors, Glucagon | 2017 |
Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.
Topics: Activin Receptors; Activins; Animals; Carbohydrate Metabolism; Carrier Proteins; Dietary Carbohydrates; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enteroendocrine Cells; Fat Body; Gastrointestinal Tract; Glucagon; Hepatocytes; Hyperglycemia; Insect Hormones; Larva; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Receptors, Glucagon; RNA Interference; RNA, Messenger; Signal Transduction | 2017 |
Suppression of islet homeostasis protein thwarts diabetes mellitus progression.
Topics: Animals; Cell Line; Diabetes Mellitus, Type 1; Female; Glucagon; HLA-D Antigens; Homeodomain Proteins; Humans; Hyperglycemia; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Proteins; Trans-Activators | 2017 |
Islet alpha cell number is maintained in microencapsulated islet transplantation.
Topics: Animals; Blood Glucose; Capsules; Cell Count; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL | 2008 |
Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.
Topics: Adenoviridae; Aging; Animals; Blood Glucose; Blotting, Western; Body Weight; Carrier Proteins; Diabetes Mellitus, Experimental; Glucagon; Glucokinase; Glucose; Hyperglycemia; Insulin; Liver; Male; Rats; Rats, Zucker | 2009 |
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Topics: Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Postprandial Period | 2008 |
Metabolic fate of plasma glucose during hyperglycemia in impaired glucose tolerance: evidence for further early defects in the pathogenesis of type 2 diabetes.
Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Clamp Technique; Glucose Intolerance; Glycogen; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Male; Middle Aged; Oxidation-Reduction | 2009 |
Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans.
Topics: Adult; Body Mass Index; C-Peptide; Cholesterol, HDL; Female; Gastric Emptying; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Kidney Function Tests; Liver Function Tests; Male; Postprandial Period; Reference Values; Young Adult | 2009 |
Insulin-producing cells derived from rat bone marrow and their autologous transplantation in the duodenal wall for treating diabetes.
Topics: Animals; Blood Glucose; Bone Marrow Cells; Bone Marrow Transplantation; Cell Culture Techniques; Cell Separation; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Experimental; Duodenum; Glucagon; Glucose Tolerance Test; Glucose Transporter Type 2; Homeodomain Proteins; Hyperglycemia; Insulin; Insulin Secretion; Intestinal Mucosa; Rats; Transplantation, Autologous; Treatment Outcome | 2009 |
Incretins in the ICU: is insulin on its way out?
Topics: Female; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Incretins; Insulin; Intensive Care Units; Male; Outcome Assessment, Health Care | 2009 |
[The role of syntaxin1A/synaptosome-associated protein-25 in reversing hyperglycemia-induced alpha cell toxicity].
Topics: Animals; Cell Line, Tumor; Cell Survival; Gene Expression; Glucagon; Hyperglycemia; Islets of Langerhans; Mice; Signal Transduction; Synaptosomal-Associated Protein 25; Syntaxin 1 | 2009 |
Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channels; Male; Mice; Mice, Knockout; Mitochondrial Proteins; Reactive Oxygen Species; Streptozocin; Uncoupling Protein 2 | 2009 |
Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucagon-Secreting Cells; Glucose; Hyperglycemia; Hyperplasia; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Glucagon; Tachyphylaxis | 2009 |
A case of recurrent type 1 diabetes mellitus with insulitis of transplanted pancreas in simultaneous pancreas-kidney transplantation from cardiac death donor.
Topics: Adult; Biopsy; Cadaver; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucagon; Graft Rejection; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Secretion; Kidney Transplantation; Pancreas Transplantation; Postoperative Complications; Recurrence; Renal Dialysis; Tissue Donors; Young Adult | 2010 |
A mathematical model of brain glucose homeostasis.
Topics: Animals; Blood-Brain Barrier; Brain; Computer Simulation; Diabetes Mellitus; Glucagon; Glucose; Homeostasis; Humans; Hyperglycemia; Insulin; Kinetics; Models, Theoretical | 2009 |
Increase in plasma glucagon, a factor in hyperglycemia, is related to neurological outcome in postcardiac-arrest patients.
Topics: Adult; Aged; Aged, 80 and over; Female; Glucagon; Heart Arrest; Humans; Hyperglycemia; Male; Middle Aged; Nervous System Diseases; Prognosis; Retrospective Studies; Risk Factors | 2010 |
Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo.
Topics: Animals; Blood Glucose; Glucagon; Glucose; Glucose Clamp Technique; Green Fluorescent Proteins; Hyperglycemia; Hypoglycemia; Islets of Langerhans; Mice; Mice, Transgenic; Microscopy, Confocal; Regional Blood Flow | 2010 |
Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Humans; Hyperglycemia; Insulin-Secreting Cells; Serum Albumin | 2010 |
Glucose flux in controlled hyperglycaemia before and after oral glucose ingestion in men with mild type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Statistics, Nonparametric | 2010 |
Streptozotocin causes pancreatic beta cell failure via early and sustained biochemical and cellular alterations.
Topics: Animals; Cell Degranulation; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Hydroxyindoleacetic Acid; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Norepinephrine; Osmolar Concentration; Pancreas; Rats; Rats, Wistar; Secretory Vesicles; Streptozocin; Time Factors; Weight Loss | 2010 |
Effects of physiological hyperglycemia on duodenal motility and flow events, glucose absorption, and incretin secretion in healthy humans.
Topics: Adult; Analysis of Variance; Area Under Curve; Blood Glucose; Duodenum; Electric Impedance; Female; Gastric Inhibitory Polypeptide; Gastrointestinal Motility; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Hyperglycemia; Incretins; Insulin; Male; Manometry; Single-Blind Method | 2010 |
Solitary concomitant endocrine tumor and ductal adenocarcinoma of pancreas.
Topics: Adenocarcinoma; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Chromogranin A; Endocrine Gland Neoplasms; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Pancreatic Neoplasms; Synaptophysin | 2010 |
Effect of anserine ingestion on hyperglycemia and the autonomic nerves in rats and humans.
Topics: Animals; Anserine; Autonomic Pathways; Blood Glucose; Cross-Over Studies; Deoxyglucose; Efferent Pathways; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Kinetics; Male; Rats; Rats, Wistar; Sympathetic Nervous System; Vagus Nerve | 2010 |
Protective effect of beta-casomorphin-7 on type 1 diabetes rats induced with streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 1; Endorphins; Glucagon; Glycogen; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Weight Gain | 2010 |
Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Glucagon; Gluconeogenesis; Glucose; Glycosuria; Humans; Hyperglycemia; Insulin Resistance; Intestinal Absorption; Liver; Postprandial Period; Reference Values; Uridine Diphosphate Glucose | 2010 |
Continuous glucose monitoring in subjects with type 1 diabetes: improvement in accuracy by correcting for background current.
Topics: Adult; Algorithms; Artificial Intelligence; Biosensing Techniques; Blood Glucose; Blood Glucose Self-Monitoring; Calibration; Data Interpretation, Statistical; Diabetes Mellitus, Type 1; Female; Glucagon; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Insulin Infusion Systems; Male; Middle Aged; Monitoring, Physiologic; Reference Standards; Reproducibility of Results | 2010 |
Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Glucagon; Glycogen; Hyperglycemia; Male; Mice; Mice, Knockout; Synaptotagmins | 2011 |
Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.
Topics: Animals; Blood Glucose; Body Composition; Brain; Corticosterone; Diabetes Mellitus, Experimental; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Leptin; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
Topics: Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Glucagon; Hyperglycemia; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Liver; Mice; Mice, Knockout; Pancreas; Radioimmunoassay; Receptors, Glucagon; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
[Malignant glucagonoma: an uncommon cause of new onset diabetes].
Topics: Adult; Alopecia; Anemia; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Chromogranin A; Combined Modality Therapy; Diabetes Mellitus; Female; Glossitis; Glucagon; Glucagonoma; Humans; Hyperglycemia; Necrolytic Migratory Erythema; Octreotide; Pancreatectomy; Pancreatic Neoplasms; Weight Loss | 2011 |
The ALBA project: an evaluation of needs, management, fears of Italian young patients with type 1 diabetes in a school setting and an evaluation of parents' and teachers' perceptions.
Topics: Adolescent; Attitude to Health; Child; Diabetes Mellitus, Type 1; Disease Management; Faculty; Fear; Glucagon; Health Services Needs and Demand; Humans; Hyperglycemia; Hypoglycemia; Insulin; Italy; Parents; Schools; Surveys and Questionnaires | 2011 |
Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Glucagon; Growth Hormone; Hyperglycemia; Leptin; Liver; Male; Mice; Mice, Inbred C57BL; Postprandial Period; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2011 |
Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Eating; Glucagon; Hyperglycemia; Insulin; Leptin; Longevity; Mice; Mice, Transgenic; Oxidative Stress; Pancreas | 2011 |
Long in the shade, glucagon re-occupies centre court.
Topics: Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia | 2011 |
Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.
Topics: Animals; Down-Regulation; Drug Administration Schedule; Glucagon; Gluconeogenesis; Glucose; Glucose Tolerance Test; Hyperglycemia; Infusion Pumps; Insulin; Insulin Secretion; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2011 |
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice.
Topics: Animals; Apoptosis; Cell Count; Diabetes Mellitus, Experimental; Diphtheria Toxin; Glucagon; Glucagon-Secreting Cells; Heparin-binding EGF-like Growth Factor; Hyperglycemia; Hypoglycemia; Insulin; Insulin-Secreting Cells; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Pancreas; Promoter Regions, Genetic; Receptors, Glucagon; Selective Estrogen Receptor Modulators; Signal Transduction; Streptozocin; Tamoxifen | 2011 |
Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.
Topics: Animals; Genes, Reporter; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channels; Islets of Langerhans; Male; Membrane Potential, Mitochondrial; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Organ Specificity; Promoter Regions, Genetic; Rats; Reactive Oxygen Species; Tissue Culture Techniques; Uncoupling Protein 2 | 2011 |
Effects of somatostatin analogs on glucose homeostasis in rats.
Topics: Animals; Blood Glucose; Glucagon; Homeostasis; Hyperglycemia; Insulin; Insulin-Like Growth Factor I; Male; Octreotide; Rats; Rats, Inbred Lew; Receptors, Somatostatin; Somatostatin | 2012 |
A pilot study of the efficacy of miglitol and sitagliptin for type 2 diabetes with a continuous glucose monitoring system and incretin-related markers.
Topics: 1-Deoxynojirimycin; Aged; Biomarkers; Blood Glucose; Case-Control Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin; Male; Middle Aged; Monitoring, Physiologic; Pilot Projects; Postprandial Period; Pyrazines; Sitagliptin Phosphate; Triazoles | 2011 |
Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.
Topics: C-Peptide; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glucagon; Glucagon-Like Peptide 1; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin-Secreting Cells; KCNQ1 Potassium Channel; Membrane Proteins; Transcription Factor 7-Like 2 Protein | 2012 |
MK-626, a dipeptidyl peptidase-4 inhibitor, does not improve the hyperglycemia or hyperinsulinemia of nonobese diabetic MKR mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Hyperinsulinism; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Obese; Phenylalanine; Triazoles | 2012 |
NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Glucagon; Glucose; Glucose Intolerance; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; NF-kappaB-Inducing Kinase; Obesity; Phosphorylation; Protein Serine-Threonine Kinases | 2012 |
Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism.
Topics: Computational Biology; Computer Simulation; Fasting; Glucagon; Gluconeogenesis; Glucose; Glycogenolysis; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Insulin; Kinetics; Liver; Liver Glycogen; Models, Biological; Postprandial Period | 2012 |
Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis.
Topics: Adipose Tissue, White; Adult; Bile Acids and Salts; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin Resistance; Intestinal Mucosa; Leptin; Liver; Liver Cirrhosis; Male; Middle Aged; Parenteral Nutrition; Postprandial Period | 2013 |
DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.
Topics: Adamantane; Animals; Blood Glucose; CCAAT-Enhancer-Binding Protein-beta; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Endoplasmic Reticulum Stress; Exenatide; Gene Expression Regulation; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Insulin; Insulin-Secreting Cells; Leupeptins; Mice; Mice, Transgenic; Nitriles; Peptides; Pyrrolidines; Venoms; Vildagliptin | 2012 |
Beta cell nuclear musculoaponeurotic fibrosarcoma oncogene family A (MafA) is deficient in type 2 diabetes.
Topics: Aged; Animals; Blood Glucose; Cell Nucleus; Cells, Cultured; Diabetes Mellitus, Type 2; Embryonic Stem Cells; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Maf Transcription Factors, Large; Male; Middle Aged; Rats; Rats, Nude | 2012 |
Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glycogen; Glycogenolysis; Human Growth Hormone; Humans; Hyperglycemia; Insulin; Liver; Male; Somatostatin | 2012 |
Regulation of glucose kinetics during exercise by the glucagon-like peptide-1 receptor.
Topics: Animals; Corticosterone; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucose; Hyperglycemia; Insulin; Kinetics; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Physical Conditioning, Animal; Receptors, Glucagon | 2012 |
Re-expression of IGF-II is important for beta cell regeneration in adult mice.
Topics: Aging; Animals; Blood Glucose; Cell Count; Glucagon; Glucose Tolerance Test; Homeostasis; Hyperglycemia; Insulin-Like Growth Factor II; Insulin-Secreting Cells; Mice; Mice, Knockout; Proto-Oncogene Proteins c-myc; Regeneration | 2012 |
Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cystic Fibrosis; Diabetes Mellitus; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Ferrets; Fibrosis; Gene Knockout Techniques; Glucagon; Glucose; Glucose Intolerance; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas, Exocrine; Pancreatic Ducts; Pancreatitis; Species Specificity | 2012 |
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.
Topics: Action Potentials; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electrophysiological Phenomena; Exocytosis; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Hyperglycemia; Mice; Potassium Channels, Voltage-Gated; Secretory Vesicles; Voltage-Gated Sodium Channels | 2013 |
BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production.
Topics: Animals; Behavior, Animal; Biological Transport; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 1; Feeding Behavior; Glucagon; Gluconeogenesis; Glucose; Hyperglycemia; Hypoglycemic Agents; Injections, Intraventricular; Insulin; Lateral Ventricles; Liver; Male; Neurons; Rats; Rats, Wistar; Ventromedial Hypothalamic Nucleus | 2013 |
Pathogenesis of prediabetes: role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Carbon Isotopes; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Glucose Intolerance; Glycogenolysis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Liver; Male; Middle Aged; Prediabetic State | 2013 |
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.
Topics: Adult; Alleles; Female; Gene Frequency; Glucagon; Glutamic Acid; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Male; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying | 2002 |
Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1.
Topics: Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemic Agents; Islet Amyloid Polypeptide; Male; Peptide Fragments; Protein Precursors | 2002 |
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Type 2; Eating; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Hyperglycemia; Insulin; Islets of Langerhans; Liraglutide; Mice; Mice, Inbred C57BL; Mice, Obese; Peptide Fragments; Peptides; Protein Precursors; Venoms | 2002 |
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.
Topics: Animals; Apoptosis; Blood Glucose; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 1; Exenatide; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hyperglycemia; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Peptide Fragments; Peptides; Protein Precursors; Venoms | 2002 |
An etiologic model proposing that non-insulin-dependent diabetes mellitus is chronic hypoxic stress hyperglycemia.
Topics: Anemia; Arteriosclerosis; Arthritis, Rheumatoid; Blood Glucose; Brain; Catecholamines; Diabetes Mellitus, Type 2; Edema; Endothelins; Endothelium, Vascular; Ephedrine; Glucagon; Hemorheology; Hydrocortisone; Hyperglycemia; Hyperplasia; Hypothalamo-Hypophyseal System; Hypoxia; Mitosis; Models, Biological; Muscle, Smooth, Vascular; Pituitary-Adrenal System; Sympathetic Nervous System; Vasodilation | 2002 |
Characterization of the portal signal in a nonsteady hyperglycemic state in conscious dogs.
Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Dogs; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Kinetics; Liver; Male; Portal Vein; Signal Transduction | 2003 |
Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.
Topics: Administration, Oral; Animals; Biological Availability; Cells, Cultured; Dogs; Glucagon; Glucose; Hepatocytes; Humans; Hydrazines; Hyperglycemia; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Structure-Activity Relationship | 2002 |
Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Dietary Proteins; Energy Intake; Exercise; Fasting; Fatty Acids; Female; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hyperglycemia; Hypertriglyceridemia; Insulin; Insulin Secretion; Male; Middle Aged; Obesity; Proinsulin; Pyrazines | 2003 |
Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy.
Topics: Animals; Blood Glucose; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Homeostasis; Hyperglycemia; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Pancreatectomy; Peptide Fragments; Protein Precursors; Receptors, Glucagon; Regeneration; Time Factors | 2003 |
Effects of inducing physiological hyperglucagonemia on metabolic responses to exercise.
Topics: 3-Hydroxybutyric Acid; Animals; Ankle; Blood Glucose; C-Peptide; Dose-Response Relationship, Drug; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Glycogen; Hyperglycemia; Infusions, Intravenous; Insulin; Liver Glycogen; Male; Muscle, Skeletal; Norepinephrine; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Reference Values | 2003 |
Glucose-induced suppression of endogenous glucose production: dynamic response to differing glucose profiles.
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Glucose Clamp Technique; Growth Hormone; Hormone Antagonists; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Male; Somatostatin | 2003 |
Influence of acute hyperglycemia in human sepsis on inflammatory cytokine and counterregulatory hormone concentrations.
Topics: Acute Disease; Adult; Female; Glucagon; Glucose Intolerance; Hormones; Humans; Hydrocortisone; Hyperglycemia; Infections; Insulin; Interleukin-6; Male; Osmolar Concentration; Tumor Necrosis Factor-alpha | 2003 |
Hyperglycemia-glycogenolytic factor in diabetic man and alloxan-diabetic animals.
Topics: Alloxan; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Humans; Hyperglycemia; Male | 1952 |
[Glucagon hyperglycemia and disordered insulin utilization in diabetes mellitus in man].
Topics: Diabetes Mellitus; Glucagon; Hormones; Humans; Hyperglycemia; Insulin; Male; Pancreas; Pancreatic Hormones | 1952 |
Glucagon; the hyperglycaemic glycogenolytic factor of the pancreas.
Topics: Glucagon; Hormones; Hyperglycemia; Pancreas | 1953 |
[Two types of diabetes mellitus; diabetes with glucagon hyperglycemia and diabetes with disturbed insulin utilization].
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Hormones; Humans; Hyperglycemia; Insulin; Pancreas; Pancreatic Hormones | 1953 |
[Glucagon].
Topics: Glucagon; Hormones; Humans; Hyperglycemia; Pancreas; Pancreatic Hormones | 1953 |
The effect of ACTH and cortisone on the hyperglycemic response to glucagon.
Topics: Adrenocorticotropic Hormone; Cortisone; Glucagon; Hormones; Hyperglycemia; Pancreas | 1954 |
Abdominal lymphatic tissue as a source of hyperglycaemic glycogenolytic factor.
Topics: Glucagon; Hormones; Humans; Hyperglycemia; Lymph Nodes; Lymphoid Tissue; Pancreas | 1954 |
Glucagon-induced hyperglycemia as in index of liver function.
Topics: Glucagon; Hormones; Humans; Hyperglycemia; Liver; Liver Function Tests; Pancreas | 1955 |
[Glucagon].
Topics: Endocrine Glands; Glucagon; Hormones; Humans; Hyperglycemia; Metabolism; Pancreas; Pancreatic Hormones | 1955 |
Analysis of the blood sugar response of obese-hyperglycemic mice and normal mice to hormones: insulin, glucagon, and epinephrine.
Topics: Animals; Blood Glucose; Epinephrine; Glucagon; Hormones; Hyperglycemia; Insulin; Mice; Mice, Obese; Obesity; Pancreas | 1956 |
Effects of pituitary growth hormone on the insulin and hyperglycaemic-glycogenolytic factor extractable from the pancreas of obese-hyperglycaemic mice.
Topics: Animals; Glucagon; Growth Hormone; Hyperglycemia; Insulin; Mice; Mice, Obese; Obesity; Pancreas | 1956 |
Turnover rates of blood glucose in normal dogs during hyperglycemia induced by glucose or glucagon.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucose; Hyperglycemia | 1958 |
[Influence of the autonomic nervous system on hyperglycemia from glucagon and hypoglycemia from N-(4-methyl-benzosulfonyl)-N'-butylurea].
Topics: Autonomic Nervous System; Blood Glucose; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Urea | 1957 |
[Hyperglycemia from glucagon and metabolism of creatine bodies. I. Urinary elimination of creatine and creatinine after glucagon administration].
Topics: Body Fluids; Creatine; Creatinine; Glucagon; Humans; Hyperglycemia | 1958 |
[Hyperglycemia from glucagon and metabolism of creatine bodies. II. Modifications of creatine and creatinine in blood].
Topics: Creatine; Creatinine; Glucagon; Humans; Hyperglycemia | 1958 |
The hyperglycaemic effect of 24-hour intravenous administration of glucagon in diabetes mellitus.
Topics: Administration, Intravenous; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia | 1958 |
[Glucagon & the sulfonylurea compounds with hypoglycemic effects; experimental studies with a standard glucagon-tolerance test].
Topics: Glucagon; Hyperglycemia; Hypoglycemic Agents; Sulfonylurea Compounds | 1958 |
Modification of glucagon-induced hyperglycemia in rats by 17-ethyl-19-nortestonsterone.
Topics: Androgens; Animals; Glucagon; Hyperglycemia; Rats | 1961 |
[Attempts at induction of a state of experimental hyperglycemia by glucagon].
Topics: Glucagon; Humans; Hyperglycemia | 1959 |
Effect of glucagon on gastric secretion in the dog.
Topics: Animals; Dogs; Gastric Juice; Glucagon; Histamine; Hyperglycemia | 1960 |
The effect of various steroids on the hyperglycemic action of glucagon.
Topics: Glucagon; Hormones; Hyperglycemia; Steroids | 1960 |
Modification of glucagon-induced hyperglycemia by various steroidal agents.
Topics: Diethylstilbestrol; Estradiol; Glucagon; Humans; Hyperglycemia; Lactates; Nandrolone | 1963 |
MECHANISM OF THE POTASSIUM MOBILIZING ACTION OF EPINEPHRINE AND GLUCAGON.
Topics: Carbon Dioxide; Cats; Dibenzylchlorethamine; Epinephrine; Ergotamine; Glucagon; Hyperglycemia; Hyperkalemia; Pharmacology; Phenoxybenzamine; Phentolamine; Phlorhizin; Potassium; Research; Sympatholytics | 1963 |
BLOOD GLUCOSE AND LIVER GLYCOGEN LEVELS IN GLUCAGON-TREATED CHICK EMBRYOS.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Chick Embryo; Glucagon; Glycoside Hydrolases; Hyperglycemia; Liver Glycogen; Pharmacology; Research | 1964 |
[GLUCAGON. CLINICAL STUDY OF ITS HYPERGLYCEMIC ACTION].
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Liver Diseases | 1964 |
LIVER GLYCOGEN DISEASE IN TWO GENERATIONS OF A FAMILY. CLINICAL STUDIES AND TISSUE ANALYSES DURING OVERT DISEASE AND AFTER APPARENT RECOVERY.
Topics: Adolescent; Biopsy; Electrocardiography; Epinephrine; Galactose; Genetics, Medical; Glucagon; Glycogen Storage Disease; Humans; Hyperglycemia; Infant; Liver; Liver Glycogen; Pathology | 1964 |
FURTHER STUDIES ON GLUCOSE METABOLISM IN EXPERIMENTAL POTASSIUM DEPLETION. EFFECT OF INSULIN, GLUCAGON, AND MUSCULAR EXERCISE.
Topics: Acidosis; Biomedical Research; Blood; Carbohydrate Metabolism; Electrocardiography; Epinephrine; Exercise Test; Glucagon; Glucose; Hyperglycemia; Hypoglycemia; Insulin; Ion Exchange Resins; Liver; Physical Exertion; Potassium | 1964 |
[STUDY OF GLUCIDE BEHAVIOR IN PREGNANCY DURING THE GLUCAGON TEST].
Topics: Carbohydrate Metabolism; Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Pharmacology; Pregnancy; Pregnancy Complications | 1964 |
[EFFECT OF GLUCAGON ON BLOOD GLUCOSE AND PLASMA NON-ESTERIFIED FATTY ACIDS CONCENTRATIONS].
Topics: Adolescent; Blood; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Humans; Hyperglycemia; Lactates; Lipid Metabolism; Liver Diseases | 1964 |
TOTAL PANCREATECTOMY IN TOADS: EFFECT OF HYPOPHYSECTOMY AND GLUCAGON.
Topics: Anura; Blood Glucose; Body Weight; Glucagon; Glycogen; Hepatectomy; Hyperglycemia; Hypophysectomy; Liver Glycogen; Metabolism; Muscles; Myocardium; Pancreas; Pancreatectomy; Pharmacology; Physiology; Research | 1964 |
RELATIVE POTENCY OF GLUCAGON AND EPINEPHRINE AS HEPATIC GLYCOGENOLYTIC AGENTS: STUDIES WITH THE ISOLATED PERFUSED RAT LIVER.
Topics: Epinephrine; Glucagon; Glycogenolysis; Hyperglycemia; Liver; Liver Glycogen; Pharmacology; Rats; Research | 1964 |
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pharmacology; Surgical Procedures, Operative; Tolbutamide | 1964 |
EFFECT OF GLYCOGENOLYTIC AGENTS ON PHOSPHORYLASE ACTIVITY OF PERFUSED RAT LIVER.
Topics: Adenine Nucleotides; Adrenocorticotropic Hormone; Carbohydrate Metabolism; Epinephrine; Glucagon; Glycogenolysis; Hyperglycemia; Insulin; Isoproterenol; Liver; Liver Glycogen; Pharmacology; Phosphorylases; Phosphotransferases; Rats; Research | 1965 |
[ON QUANTITATIVE STUDIES OF THE GLYCOGEN CONTENT OF THE LIVER IN HEALTHY AND DISEASED SUBJECTS. 3. ACTION MECHANISM OF GLUCAGON].
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Glycogen; Humans; Hyperglycemia; Insulin; Liver; Liver Glycogen; Pharmacology; Rabbits | 1965 |
TOTAL PANCREATECTOMY IN LIZARDS. EFFECTS OF SEVERAL HORMONES.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Cortisone; Epinephrine; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemia; Insulin; Ketone Bodies; Lizards; Pancreas; Pancreatectomy; Pharmacology; Physiology; Pituitary Hormones; Pituitary Hormones, Anterior; Reptiles; Research; Surgical Procedures, Operative | 1965 |
[STUDIES ON THE METABOLISM OF CARBOHYDRATES IN CHAGAS' DISEASE. II. THE GLUCAGON TEST].
Topics: Blood Glucose; Chagas Disease; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; United States | 1965 |
The influence of hyperglycaemic glycogenolytic factor (HGF) on glycogenolysis in skin.
Topics: Glucagon; Glycogen; Glycogenolysis; Hormones; Hyperglycemia; Pancreas; Pancreatic Hormones; Skin | 1955 |
Mode of action of the hyperglycemic-glycogenolytic factor from urine.
Topics: Body Fluids; Glucagon; Glycogen; Hyperglycemia; Urine | 1955 |
[Glucagon, glucogenolätico FHG-hyperglycaemic factor].
Topics: Glucagon; Hormones; Humans; Hyperglycemia; Pancreas | 1954 |
Enhancing effect of vasopressin on the hyperglycemic response to carotid body chemoreceptor stimulation. Role of metabolic variables.
Topics: Animals; Arginine Vasopressin; Blood Glucose; Brain; Carotid Body; Chemoreceptor Cells; Epinephrine; Glucagon; Glucose; Homeostasis; Hyperglycemia; Male; Rats; Rats, Wistar; Solitary Nucleus | 2003 |
Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.
Topics: Amino Acids; Animals; Dihydropyridines; Dogs; Enzyme Inhibitors; Female; Fructosephosphates; Furans; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphate; Glycogen Phosphorylase; Hyperglycemia; Insulin; Lactic Acid; Liver; Male | 2004 |
Does hyperoxia affect glucose regulation and transport in the newborn?
Topics: Animals; Animals, Newborn; Blood Glucose; Epinephrine; Glucagon; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hyperglycemia; Hyperoxia; Insulin; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Oxygen; Swine | 2003 |
An in vivo test for the hyperglycaemic glycogenolytic factor in insulin.
Topics: Glucagon; Humans; Hyperglycemia; Insulin | 1951 |
Transient chylomicronemia preceding the onset of insulin-dependent diabetes in a young girl with no humoral markers of islet autoimmunity.
Topics: Autoantibodies; Autoimmunity; C-Peptide; Child; Chylomicrons; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose Clamp Technique; Humans; Hypercholesterolemia; Hyperglycemia; Hypertriglyceridemia; Islets of Langerhans; Lipoprotein Lipase | 2004 |
Long-term correction of hyperglycemia in diabetic mice after implantation of cultured human cells derived from fetal pancreas.
Topics: Animals; Biomarkers; Cell Differentiation; Cell Separation; Clone Cells; Diabetes Mellitus, Experimental; Fetal Tissue Transplantation; Glucagon; Humans; Hyperglycemia; Insulin; Intermediate Filament Proteins; Islets of Langerhans; Keratins; Mice; Mice, SCID; Nerve Tissue Proteins; Nestin; Pancreas; Polylysine; Stem Cell Transplantation; Streptozocin; Transplantation, Heterologous; Vimentin | 2004 |
Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog.
Topics: Amino Acids; Animals; Blood Glucose; Dogs; Epinephrine; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Hyperglycemia; Insulin; Kidney; Lactic Acid; Male | 2004 |
Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver.
Topics: Animals; Axonal Transport; Bicuculline; Blood Glucose; Circadian Rhythm; Clonidine; Corticosterone; gamma-Aminobutyric Acid; Glucagon; Gluconeogenesis; Herpesvirus 1, Suid; Hyperglycemia; Hypothalamus; Insulin; Isoproterenol; Liver; Male; Microdialysis; Muscimol; N-Methylaspartate; Norepinephrine; Parasympathectomy; Parasympathetic Nervous System; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Sympathectomy; Sympathetic Nervous System; Tetrodotoxin; Vasopressins | 2004 |
Hypoplasia of endocrine and exocrine pancreas in homozygous transgenic TGF-beta1.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p15; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Homozygote; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; Pancreas, Exocrine; Promoter Regions, Genetic; Swine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Proteins | 2005 |
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.
Topics: Animals; Cell Differentiation; Cell Line; Chlorocebus aethiops; COS Cells; Female; Gene Expression Regulation, Developmental; Glucagon; Homeodomain Proteins; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Paired Box Transcription Factors; Somatostatin; Transcription Factors; Transcription, Genetic | 2005 |
Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes.
Topics: Alanine; Blood Glucose; Carbon Dioxide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose; Glycerol; Glycogenolysis; Glycolysis; Humans; Hyperglycemia; Insulin; Lactic Acid; Male; Middle Aged; Oxidation-Reduction; Postprandial Period; Viscera; Water | 2006 |
Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucose; Glycerol; Hyperglycemia; Infusions, Intravenous; Insulin; Lactic Acid; Liver; Liver Circulation; Norepinephrine; Portal System; Somatostatin; Sympathectomy; Sympathetic Nervous System | 2006 |
Impact of glucagon response on postprandial hyperglycemia in men with impaired glucose tolerance and type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Proteins; Fasting; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Multivariate Analysis; Postprandial Period | 2005 |
VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity.
Topics: Adipose Tissue; Animals; Diet; Disease Models, Animal; Disease Susceptibility; Energy Intake; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neuropeptides; Obesity; Proteins; Receptor, Melanocortin, Type 4 | 2005 |
Serum glucagon counterregulatory hormonal response to hypoglycemia is blunted in congenital hyperinsulinism.
Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Child, Preschool; Diazoxide; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Homeostasis; Hormones; Humans; Hyperglycemia; Hyperinsulinism; Infant; Insulin; Islets of Langerhans; Ketone Bodies; Male; Mutation; Norepinephrine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2005 |
A model of controlled acute hyperglycemia in rats: Effects of insulin and glucagon-like peptide-1 analog.
Topics: Acute Disease; Anesthesia; Animals; Disease Models, Animal; Glucagon; Glucagon-Like Peptide 1; Glucose; Growth Hormone; Hyperglycemia; Insulin; Male; Rats; Rats, Sprague-Dawley | 2006 |
Desperately seeking sugar: glial cells as hypoglycemia sensors.
Topics: Animals; Astrocytes; Blood Glucose; Cell Membrane; Glucagon; Glucagon-Secreting Cells; Glucose; Glucose Transporter Type 2; Hyperglycemia; Hypoglycemia; Insulin; Mice; Mice, Inbred C57BL; Models, Biological; Neuroglia; Neurons | 2005 |
Burn-induced alterations of chromium and the glucose/insulin system in rats.
Topics: Animals; Blood Glucose; Burns; Chromium; Corticosterone; Glucagon; Hyperglycemia; Insulin; Insulin-Like Growth Factor I; Male; Rats; Rats, Wistar | 2006 |
Insulin and glucagon ratio in the patho-physiology of diabetic ketoacidosis and hyperosmolar hyperglycemic non-ketotic diabetes.
Topics: Case-Control Studies; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male | 2006 |
Arginine-vasopressin mediates central and peripheral glucose regulation in response to carotid body receptor stimulation with Na-cyanide.
Topics: Adrenal Glands; Adrenalectomy; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Brain Chemistry; Carotid Body; Catecholamines; Chemoreceptor Cells; Enzyme Inhibitors; Glucagon; Glucose; Hyperglycemia; Hypoxia; Liver; Male; Rats; Rats, Wistar; Receptors, Vasopressin; Sodium Cyanide; Vasopressins | 2006 |
The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Blood Glucose; Cyclic AMP; Dogs; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Glycerol; Glycogenolysis; Heparin; Hyperglycemia; Insulin; Lactic Acid; Liver | 2006 |
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Liver; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription Factors | 2006 |
Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
Topics: Animals; Blood Glucose; Carbonates; Carrier Proteins; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Glucokinase; Glucose; Glucose-6-Phosphatase; Glucosides; Glycogen; Glycogen Synthase; Hyperglycemia; Insulin; Liver; Liver Glycogen; Male; Muscle, Skeletal; Phosphorylases; Rats; Rats, Zucker | 2006 |
Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.
Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Hyperglycemia; Liver; Liver Glycogen; Male; Mice; Mice, Obese | 2006 |
Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor.
Topics: Animals; Blood Glucose; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cyclic AMP; Dietary Fats; Drug Design; Gastric Inhibitory Polypeptide; Glucagon; Half-Life; Humans; Hyperglycemia; Indicators and Reagents; Mice; Mice, Transgenic; Molecular Conformation; Receptors, Glucagon; Urea | 2007 |
Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance.
Topics: Blood Glucose; C-Peptide; Fasting; Female; Glucagon; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Postprandial Period; Prediabetic State; Reference Values | 2006 |
Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia.
Topics: Adolescent; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Male; Middle Aged; Norepinephrine; Reference Values | 2007 |
[Study of relationship between stress hyperglycemia and insulin-resistance related factors].
Topics: Adult; Aged; C-Peptide; Critical Illness; Female; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Intensive Care Units; Male; Middle Aged; Stress, Physiological; Tumor Necrosis Factor-alpha; Young Adult | 2006 |
Evidence for the presence of a glucosensor in hypothalamus, hindbrain, and Brockmann bodies of rainbow trout.
Topics: Animals; Blood Glucose; Cattle; Deoxyglucose; Glucagon; Glucokinase; Glucose; Glucose Transporter Type 2; Glycogen; Hexokinase; Hormones; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Insulin; Islets of Langerhans; Mesencephalon; Oncorhynchus mykiss; Rhombencephalon; Telencephalon; Time Factors | 2007 |
Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo.
Topics: Animals; Blood Glucose; C-Peptide; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Hypoglycemia; Insulin; Male; Rats; Rats, Wistar; Streptozocin; Zinc | 2007 |
Fasting hyperglycemia impairs glucose- but not insulin-mediated suppression of glucagon secretion.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Mexican Americans | 2007 |
Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis.
Topics: Adipose Tissue; Blood Glucose; Body Mass Index; C-Peptide; Fasting; Female; Glucagon; Gluconeogenesis; Glucose Intolerance; Humans; Hyperglycemia; Insulin Resistance; Liver; Male; Middle Aged; Reference Values | 2007 |
Impaired first-phase insulin response predicts postprandial blood glucose increment in patients with recently diagnosed type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Middle Aged; Postprandial Period; Predictive Value of Tests; Reference Values; Sensitivity and Specificity | 2007 |
Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition.
Topics: Animal Feed; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glycogen; Glycogen Synthase; Glycogenolysis; Homeostasis; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Obesity; Receptors, Somatostatin; Triglycerides | 2007 |
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes.
Topics: Adolescent; ATP-Binding Cassette Transporters; Blotting, Western; C-Peptide; Child; Diabetes Mellitus, Type 1; Eating; Female; Gastric Inhibitory Polypeptide; Genotype; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Ileum; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Polymorphism, Restriction Fragment Length; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2007 |
Recurrent intermittent restraint delays fed and fasting hyperglycemia and improves glucose return to baseline levels during glucose tolerance tests in the Zucker diabetic fatty rat--role of food intake and corticosterone.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Type 2; Eating; Glucagon; Glucose Tolerance Test; Hormones; Hyperglycemia; Insulin; Leptin; Lipids; Male; Organ Size; Rats; Rats, Zucker; Regression Analysis; Restraint, Physical; Stress, Psychological | 2007 |
Editorial: The role of glucagon in postprandial hyperglycemia--the jury's still out.
Topics: Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Postprandial Period; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Sulfonylurea Compounds | 2007 |
Noninvasive assessment of the effects of glucagon on the gastric slow wave.
Topics: Electromagnetic Fields; Glucagon; Humans; Hyperglycemia; Magnetics; Reference Values; Stomach; Surface Properties | 2007 |
An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.
Topics: Animals; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Glucose; Glucose Tolerance Test; Glycogen Phosphorylase; Glycogen Synthase; Hepatocytes; Hyperglycemia; Inhibitory Concentration 50; Male; Obesity; Quinolones; Rats; Rats, Wistar; Rats, Zucker; Thiophenes | 2007 |
Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization.
Topics: Animals; Blood Glucose; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; Infusions, Intravenous; Insulin; Liver Circulation; Male | 2008 |
Effects of gastric inhibitory polypeptide (GIP) and related analogues on glucagon release at normo- and hyperglycaemia in Wistar rats and isolated islets.
Topics: Animals; Blood Glucose; Gastric Inhibitory Polypeptide; Glucagon; Hyperglycemia; Islets of Langerhans; Rats; Rats, Wistar; Structure-Activity Relationship | 2008 |
Glucagon and hyperglycaemia in diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Fasting; Glucagon; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin | 2008 |
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Glucose; Diabetes Mellitus, Type 2; Exenatide; Female; Gastric Emptying; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Peptides; Postprandial Period; Triglycerides; Venoms | 2008 |
Effect upon insulin secretion of physiologic doses of glucagon administered via the portal vein.
Topics: Animals; Dogs; Glucagon; Hyperglycemia; Infusions, Parenteral; Injections, Intravenous; Insulin; Portal Vein | 1967 |
Glutamate-induced hyperglycemia.
Topics: Adrenal Glands; Adrenalectomy; Alanine; Animals; Blood Glucose; Carbon Isotopes; Glucagon; Gluconeogenesis; Glutamates; Hyperglycemia; Male; Pyruvates; Rats | 1967 |
[Glycoregulation and carbon monoxide coma].
Topics: Adult; Aged; Carbon Monoxide Poisoning; Diabetic Coma; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Middle Aged; Tolbutamide | 1967 |
Effect of hyperglycemia independent of changes in insulin or glucagon on lipolysis in the conscious dog.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Hyperglycemia; Insulin; Lipolysis; Liver; Male; Somatostatin | 1980 |
Catecholamine-induced hyperglycemia in dogs: independence from alterations in pancreatic hormone release.
Topics: Animals; Blood Glucose; Dogs; Epinephrine; Glucagon; Hyperglycemia; Insulin; Isoproterenol; Lactates; Male; Somatostatin | 1980 |
Endogenous hyperglycemia restores insulin release impaired by somatostatin analogue.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dogs; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1981 |
Responses of neonatal rat islets to streptozotocin: limited B-cell regeneration and hyperglycemia.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Body Weight; Eating; Female; Glucagon; Hyperglycemia; Insulin; Islets of Langerhans; Male; Rats; Regeneration; Sex Factors; Somatostatin; Streptozocin | 1981 |
Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Glycerol; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Reference Values; Somatostatin | 1981 |
Retardant effect of hyperglycemia on the rise in plasma fatty acids following insulin withdrawal in man.
Topics: Adolescent; Adult; Fatty Acids, Nonesterified; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Kinetics; Male; Somatostatin | 1981 |
Role of epinephrine-mediated beta-adrenergic mechanisms in hypoglycemic glucose counterregulation and posthypoglycemic hyperglycemia in insulin-dependent diabetes mellitus.
Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus; Epinephrine; Female; Glucagon; Heart Rate; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male; Norepinephrine | 1982 |
Differential effects of insulin on splanchnic and peripheral glucose disposal after an intravenous glucose load in man.
Topics: Adult; Blood Circulation; Blood Flow Velocity; Blood Glucose; Dose-Response Relationship, Drug; Forearm; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Parenteral; Insulin; Kinetics; Liver; Male; Muscles; Somatostatin; Splanchnic Circulation | 1982 |
Failure of glucagon to stimulate ketone body production during acute insulin deficiency or insulin replacement in man.
Topics: Adult; Aged; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ketone Bodies; Kinetics; Male; Middle Aged; Somatostatin | 1982 |
Effect of hyperglycemia per se on glucose disposal and clearance in noninsulin-dependent diabetics.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Epinephrine; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Metabolic Clearance Rate; Middle Aged; Somatostatin | 1983 |
Minimal increases in glucagon levels enhance glucose production in man with partial hypoinsulinemia.
Topics: Adult; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Somatostatin | 1983 |
Effects of a long-acting somatostatin analogue on postprandial hyperglycemia in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Somatostatin; Triglycerides; Xylose | 1983 |
Hyperglycemia and beta-cell adaptation during prolonged somatostatin infusion with glucagon replacement in man.
Topics: Adaptation, Physiological; Adolescent; Adult; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Isoproterenol; Male; Somatostatin; Time Factors | 1983 |
A super active cyclic hexapeptide analog of somatostatin.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Growth Hormone; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Mice; Oligopeptides; Peptides, Cyclic; Rats; Somatostatin; Structure-Activity Relationship | 1984 |
Roles of glucagon and epinephrine in hypoglycemic and nonhypoglycemic glucose counterregulation in humans.
Topics: Adrenalectomy; Blood Glucose; Epinephrine; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Phentolamine; Propranolol; Somatostatin | 1984 |
Hyperglycemic effect of neurotensin.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Blood Pressure; Denervation; Dogs; Glucagon; Growth Hormone; Hydrocortisone; Hyperglycemia; Insulin; Neurotensin; Phentolamine; Pressoreceptors; Somatostatin | 1984 |
Effects of morphine on glucose homeostasis in the conscious dog.
Topics: Animals; Blood Glucose; Dogs; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Homeostasis; Hyperglycemia; Insulin; Kinetics; Ligation; Male; Morphine; Somatostatin | 1984 |
Changes in glucose tolerance after endoscopic retrograde cholangiopancreatography.
Topics: Amylases; Blood Glucose; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Follow-Up Studies; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin | 1981 |
Adrenergic mechanisms for the effects of epinephrine on glucose production and clearance in man.
Topics: Adult; Blood Glucose; Epinephrine; Glucagon; Humans; Hyperglycemia; Insulin; Male; Phentolamine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Insulin insensitivity and hyposuppressibility of glucagon by hyperglycemia in aged Wistar rats.
Topics: Aging; Animals; Cell Membrane; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Liver; Male; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Cell Surface | 1982 |
Hyperglycemia of diabetic rats decreased by a glucagon receptor antagonist.
Topics: Animals; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Male; Rats; Receptors, Cell Surface; Receptors, Glucagon; Structure-Activity Relationship | 1982 |
Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man.
Topics: Adult; Blood Glucose; Female; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Liver; Male; Splanchnic Circulation | 1983 |
Glucose tolerance in aging obese (ob/ob) and lean mice.
Topics: Aging; Animals; Corticosterone; Fasting; Female; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Male; Mice; Mice, Obese | 1983 |
Insulin or glucagon choleresis in the isolated perfused guinea pig liver.
Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Glucagon; Guinea Pigs; Hyperglycemia; Insulin; Liver; Perfusion | 1983 |
[Maternal hyperglycemia and fetal development in the rat: effects of a continuous glucose perfusion in the rat at the end of gestation].
Topics: Animals; Blood Glucose; Female; Fetus; Gestational Age; Glucagon; Glucose; Hyperglycemia; Insulin; Liver; Pancreas; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Rapid alterations in substrate profiles after partial hepatectomy in the rat.
Topics: Amino Acids; Animals; Glucagon; Hepatectomy; Hyperglycemia; Hypoglycemia; Insulin; Lipids; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
The Somogyi phenomenon. Sacred cow or bull?
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Epinephrine; Food; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin | 1984 |
Hyperglycaemia in infantile gastroenteritis.
Topics: Child, Preschool; Fatty Acids, Nonesterified; Fluid Therapy; Gastroenteritis; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Infant; Insulin | 1984 |
Glucose counterregulation and waning of insulin in the Somogyi phenomenon (posthypoglycemic hyperglycemia).
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Insulin Resistance; Male; Norepinephrine | 1984 |
Degranulation effect of ferric nitrilotriacetate (Fe3+-NTA) on the pancreatic islet beta-cells: its acute toxic effect on glucose metabolism.
Topics: Animals; Cytoplasmic Granules; Ferric Compounds; Glucagon; Glucose; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Secretion; Iron; Islets of Langerhans; Male; Nitrilotriacetic Acid; Rabbits; Rats; Rats, Inbred Strains | 1984 |
Determinants of glucose and ketoacid concentrations in acutely hyperglycemic diabetic patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hyperglycemic Hyperosmolar Nonketotic Coma; Keto Acids; Male; Middle Aged; Models, Biological; Regression Analysis | 1984 |
Naloxone decreases centrally induced hyperglycemia in dogs. Evidence for an opioid role in glucose homeostasis.
Topics: Animals; Blood Glucose; Brain; Deoxyglucose; Dogs; Endorphins; Glucagon; Glucose; Homeostasis; Hyperglycemia; Naloxone; Radioimmunoassay | 1984 |
Mechanisms of insulin resistance following injury.
Topics: Adult; Blood Glucose; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Male; Middle Aged; Wounds and Injuries | 1982 |
Different endocrinological properties, growth rate and sensitivity to chemotherapy of aplastic mammary carcinoma in normo- and hypoglycemic phase of tumor growth.
Topics: Animals; Cyclophosphamide; DNA, Neoplasm; Female; Glucagon; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Leukocyte Count; Lymphocyte Activation; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation | 1982 |
Effect of adrenergic drugs on glucose and plasma glucagon and insulin responses to xylazine in sheep.
Topics: Animals; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Phentolamine; Propranolol; Sheep; Sheep Diseases; Thiazines; Xylazine | 1982 |
Benefits and risks of meticulous control of diabetes.
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Insulin; Risk; Self Care | 1982 |
[Blood insulin, glucagon and glucose levels in latent diabetes mellitus determined during glucose tolerance test (effect of phenformin)].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Middle Aged; Phenformin | 1982 |
Insulin and glucagon response during hemorrhage induced hyperglycemia.
Topics: Adrenalectomy; Animals; Autonomic Nervous System; Cats; Denervation; Electric Stimulation; Glucagon; Hemorrhage; Hyperglycemia; Insulin; Liver | 1982 |
Regional distribution of glucagon-like immunoreactive material in the brain of rats and sand rats. An immunohistochemical investigation.
Topics: Amygdala; Animals; Arvicolinae; Brain Chemistry; Cerebral Ventricles; Fluorescent Antibody Technique; Glucagon; Hyperglycemia; Hypothalamus, Anterior; Median Eminence; Rats; Thalamus | 1980 |
Modulation of arginine-induced glucagon release by epinephrine and glucose levels in man.
Topics: Adult; Arginine; Blood Glucose; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Parenteral; Male; Middle Aged; Regression Analysis | 1983 |
Glucagon physiology and aging: evidence for enhanced hepatic sensitivity.
Topics: Adult; Aged; Aging; Alanine; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Hyperinsulinism; Kinetics; Liver; Male; Middle Aged; Stimulation, Chemical | 1983 |
Synergistic interactions of counterregulatory hormones: a mechanism for stress hyperglycemia.
Topics: Animals; Blood Glucose; Dogs; Drug Synergism; Epinephrine; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Stress, Physiological | 1980 |
Stimulation of counterregulatory hormonal responses in diabetic man by a fall in glucose concentration.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Epinephrine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Kinetics; Middle Aged; Norepinephrine | 1980 |
Circulating immunoreactive glucagon concentrations in aging obese-hyperglycaemic (ob/ob) mice [proceedings].
Topics: Animals; Blood Glucose; Body Weight; Genotype; Glucagon; Homozygote; Hyperglycemia; Insulin; Mice; Mice, Obese | 1980 |
Glucagon and diabetes: evidence for marked insensitivity to local regulation of A-cell function by endogenous insulin in obese-hyperglycaemic (ob/ob) mice [proceedings].
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Homozygote; Hyperglycemia; Insulin; Mice; Mice, Obese; Obesity; Pancreas; Starvation | 1980 |
Effect of alpha-adrenergic stimulation and its blockade on glucose turnover in man.
Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Phentolamine; Propranolol | 1980 |
Morphine-induced hyperglycemia: role of insulin and glucagon.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Hyperglycemia; Insulin; Morphine | 1980 |
Stress hyperglycemia and the adrenergic regulation of pancreatic hormones in hypoxia.
Topics: Animals; Blood Glucose; Dogs; Epinephrine; Glucagon; Hyperglycemia; Hypoxia; Insulin; Isoproterenol; Phentolamine | 1980 |
[Behavior of plasma insulin, C-peptide and glucagon in normal subjects and in patients with liver cirrhosis].
Topics: Adult; Aged; Ascites; C-Peptide; Female; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Liver Cirrhosis; Male; Middle Aged; Peptides | 1980 |
Hyperkalemia and hyperglycemic increments in plasma potassium in diabetes mellitus.
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Epinephrine; Female; Glucagon; Humans; Hypercalcemia; Hyperglycemia; Hyperkalemia; Insulin; Male; Middle Aged; Norepinephrine; Potassium | 1980 |
[Physiopathology of non-ketotic hyperosmolar coma in diabetes (author's transl)].
Topics: Blood; Dehydration; Diabetic Coma; Glucagon; Humans; Hyperglycemia; Hyperglycemic Hyperosmolar Nonketotic Coma; Insulin; Kinetics; Osmolar Concentration; Sodium; Uremia; Vasopressins | 1980 |
The metabolic response to hyperglycaemic clamping in insulin-dependent diabetes.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Hyperglycemia; Insulin; Ketone Bodies; Lactates; Male; Middle Aged; Pyruvates; Reference Values | 1981 |
Response of extrapancreatic glucagon to glycemic changes.
Topics: Animals; Arginine; Blood Glucose; Deoxyglucose; Dogs; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Insulin; Male; Middle Aged; Portacaval Shunt, Surgical | 1980 |
Synergistic interactions among antiinsulin hormones in the pathogenesis of stress hyperglycemia in humans.
Topics: Adult; Blood Glucose; Drug Synergism; Epinephrine; Female; Glucagon; Humans; Hydrocortisone; Hyperglycemia; Insulin; Kinetics; Male | 1981 |
Glucagon in spontaneously diabetic KK mice.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Insulin; Jejunum; Male; Mice; Organ Size; Pancreas; Stomach | 1981 |
Importance of glucagon in mediating epinephrine-induced hyperglycemia in alloxan-diabetic dogs.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Dogs; Epinephrine; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics | 1981 |
[Evaluation of immunoreactive serum levels of insulin, C peptide and glucagon in patients with acute pancreatitis and acute abdominal pain of non-pancreatic origin (author's transl)].
Topics: Abdomen, Acute; Acute Disease; Adult; Aged; C-Peptide; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Pancreatitis; Peptides | 1982 |
Transient hepatic response to glucagon in man: role of insulin and hyperglycemia.
Topics: Adult; Aged; Blood Glucose; Female; Glucagon; Gluconeogenesis; Humans; Hyperglycemia; Insulin; Liver; Male; Middle Aged | 1982 |
Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: metabolic and hormonal changes in the mother and the fetuses.
Topics: Animals; Blood Glucose; Body Weight; Female; Fetus; Glucagon; Glucose; Hyperglycemia; Insulin; Liver; Liver Glycogen; Male; Pancreatic Hormones; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Pregnancy Complications; Rats | 1981 |
Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice.
Topics: Aging; Animals; Female; Glucagon; Hyperglycemia; Hyperplasia; Insulin; Islets of Langerhans; Male; Mice; Mice, Obese | 1982 |
[Carbohydrate tolerance in the cirrhotic patient].
Topics: Dietary Carbohydrates; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Glycogen | 1981 |
[Changes in glucose tolerance following endoscopic retrograde cholangiopancreatography].
Topics: Cholangiopancreatography, Endoscopic Retrograde; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Pancreatitis; Secretory Rate | 1981 |
Effect of glucose, independent of changes in insulin and glucagon secretion, on alanine metabolism in the conscious dog.
Topics: Alanine; Animals; Blood Glucose; Dogs; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Lactates; Male; Time Factors | 1980 |
Glucagon stimulates insulin-like growth factor binding protein-1 secretion in healthy subjects, patients with pituitary insufficiency, and patients with insulin-dependent diabetes mellitus.
Topics: Adult; Carrier Proteins; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Insulin-Like Growth Factor Binding Protein 1; Male; Middle Aged; Reference Values; Somatomedins | 1993 |
Characterization of insulin-dependent diabetes mellitus induced by a new variant (DK-27) of encephalomyocarditis virus in DBA/2 mice.
Topics: Animals; Blood Glucose; Cardiovirus Infections; Diabetes Mellitus, Type 1; Disease Models, Animal; Encephalomyocarditis virus; Glucagon; Glycated Hemoglobin; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred DBA; Pancreas; Virus Replication | 1995 |
Suppressive effect of vasopressin on the hyperglycemic response to intracranial injection of 2-deoxy-D-glucose.
Topics: Animals; Blood Glucose; Deoxyglucose; Glucagon; Hyperglycemia; Hypothalamus; Insulin; Male; Rats; Rats, Wistar; Time Factors; Vasopressins | 1995 |
Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Glycolysis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Liver Glycogen; Male; Muscle, Skeletal; Myocardium; Organ Specificity; Rats; Rats, Wistar; Reference Values | 1995 |
Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Eating; Female; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Kinetics; Liver; Male; Portal System; Radioisotope Dilution Technique; Somatostatin; Time Factors; Tritium | 1995 |
Diabetic ketoacidosis in obese African-Americans.
Topics: Adult; Black People; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Georgia; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin Secretion; Male; Middle Aged; Obesity; Reference Values; Thinness | 1995 |
Exacerbation of verapamil-induced hyperglycemia with glucagon.
Topics: Animals; Dogs; Glucagon; Hyperglycemia; Verapamil | 1995 |
Diminished diabetogenic effect of streptozotocin in adrenodemedullated rats.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Pancreas; Rats; Rats, Wistar; Streptozocin | 1994 |
Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats.
Topics: Animals; Antibodies, Monoclonal; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; Hyperglycemia; Insulin; Male; Rats; Rats, Sprague-Dawley; Streptozocin | 1994 |
The possible role of age-related increase in the plasma glucagon/insulin ratio in the enhanced hepatic gluconeogenesis and hyperglycemia in genetically diabetic (C57BL/KsJ-db/db) mice.
Topics: Age Factors; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glucose-6-Phosphatase; Hyperglycemia; Insulin; Liver; Mice; Mice, Inbred C57BL | 1994 |
Insulinopenia and hyperglycemia influence the in vivo partitioning of GE and SI.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Glycogen Synthase; Hyperglycemia; Insulin; Lactates; Lactic Acid; Male; Muscle, Skeletal; Somatostatin | 1995 |
Effects of glucose on hepatic conversion of aminonitrogen to urea in patients with cirrhosis: relationship to glucagon.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Blood Glucose; Female; Glucagon; Glucose; Humans; Hyperglycemia; Liver; Liver Cirrhosis; Male; Middle Aged; Nitrogen; Somatostatin; Urea | 1994 |
Effect of sustained hyperglycemia on the release of insulin from the isolated perfused rat pancreas.
Topics: Animals; Arginine; Glucagon; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Male; Pancreas; Radioimmunoassay; Rats; Rats, Wistar | 1993 |
Permissive effect of VIP on the hyperglycemic response induced by 2-deoxy-D-glucose.
Topics: Analysis of Variance; Animals; Antibodies; Blood Glucose; Cerebral Ventricles; Deoxyglucose; Glucagon; Hyperglycemia; Injections, Intraventricular; Kinetics; Male; Microinjections; Neurons; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Time Factors; Vasoactive Intestinal Peptide | 1994 |
Natural history of B-cell dysfunction in spontaneously diabetic Chinese hamsters.
Topics: Amyloid; Animals; Blood Glucose; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Female; Glucagon; Glucose Tolerance Test; Hyperglycemia; Immunohistochemistry; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Longitudinal Studies; Male; Pancreas | 1994 |
Effect of lithium on plasma glucose, insulin and glucagon in normal and streptozotocin-diabetic rats: role of glucagon in the hyperglycaemic response.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Hyperglycemia; Insulin; Lithium; Male; Rats; Rats, Wistar | 1994 |
Effects of glipizide on glucose metabolism and muscle content of the insulin-regulatable glucose transporter (GLUT 4) and glycogen synthase activity during hyperglycaemia in type 2 diabetic patients.
Topics: Adult; Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glipizide; Glucagon; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Glycogen Synthase; Humans; Hyperglycemia; Male; Middle Aged; Monosaccharide Transport Proteins; Muscle Proteins; Muscles | 1994 |
Differential effects of hyperglycemia and hyperinsulinemia on leucine rate of appearance in normal humans.
Topics: Adult; Blood Glucose; Female; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Infusion Systems; Leucine; Male; Middle Aged; Reference Values; Somatostatin | 1993 |
Alpha 2-adrenergic blockade prevents hyperglycemia and hepatic glutathione depletion in nickel-injected rats.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Female; Glucagon; Glutathione; Hyperglycemia; Insulin; Liver; Nickel; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Yohimbine | 1993 |
Effect of hyperglycaemia on gallbladder motility in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Blood Glucose; Cholecystokinin; Diabetes Mellitus, Type 1; Female; Gallbladder; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Pancreatic Polypeptide; Reference Values; Ultrasonography | 1994 |
Enhancement by succinic acid dimethyl ester of insulin release evoked by D-glucose and glimepiride in the perfused pancreas of normoglycemic and hyperglycemic rats.
Topics: Animals; Diabetes Mellitus, Type 2; Drug Synergism; Female; Glucagon; Glucose; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Pancreas; Rats; Rats, Wistar; Succinates; Sulfonylurea Compounds | 1994 |
Acute metabolic effects of clenbuterol in calves.
Topics: Animals; Blood Glucose; Cattle; Clenbuterol; Glucagon; Hyperglycemia; Hyperinsulinism; Insulin | 1993 |
Lack of effect of hyperglycemia on lipolysis in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Growth Hormone; Humans; Hyperglycemia; Insulin; Lipolysis; Male; Palmitic Acid; Palmitic Acids; Radioimmunoassay; Time Factors | 1993 |
Octreotide: a long-acting inhibitor of endogenous hormone secretion for human metabolic investigations.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Dose-Response Relationship, Drug; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Octreotide; Radioimmunoassay; Time Factors | 1994 |
Myocardial glucose transporters and glycolytic metabolism during ischemia in hyperglycemic diabetic swine.
Topics: Animals; Coronary Vessels; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Transporter Type 4; Glycolysis; Hyperglycemia; Lactates; Microspheres; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Ischemia; Myocardium; Regional Blood Flow; Streptozocin; Swine | 1994 |
Opposite effects of hyperglycemia and insulin deficiency on liver glycogen synthase phosphatase activity in the diabetic rat.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucokinase; Glucose; Glucose-6-Phosphatase; Glycogen-Synthase-D Phosphatase; Hexosephosphates; Hyperglycemia; Insulin; Liver; Male; Phlorhizin; Rats; Rats, Sprague-Dawley | 1993 |
Glucagon-like peptide-I-(7-37) suppresses hyperglycemia in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Dose-Response Relationship, Drug; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hyperglycemia; Insulin; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values | 1993 |
Exaggerated hyperglycemia after a pizza meal in well-controlled diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Fatty Acids, Nonesterified; Female; Food; Glucagon; Humans; Hyperglycemia; Insulin; Male; Time Factors | 1993 |
The role of pancreatic insulin secretion in neonatal glucoregulation. II. Infants with disordered blood glucose homoeostasis.
Topics: Blood Glucose; Glucagon; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Insulin; Insulin Secretion; Pancreas | 1993 |
Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Synergism; Fasting; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Pancreas; Pancreatectomy; Peptide Fragments; Peptides; Proinsulin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1996 |
Systemic absorption of insulin and glucagon applied topically to the eyes of rats and a diabetic dog.
Topics: Absorption; Administration, Topical; Animals; Blood Glucose; Detergents; Diabetes Mellitus; Dogs; Drug Carriers; Eye; Gastrointestinal Agents; Glucagon; Glucosides; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nasal Mucosa; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley | 1995 |
Inability of hyperglycemia to counter the ability of glucagon to increase net glucose output and activate glycogen phosphorylase in the perfused rat liver.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Glucose; Hyperglycemia; Insulin; Liver; Male; Perfusion; Phosphorylases; Rats; Rats, Sprague-Dawley | 1996 |
Epidermal growth factor administration decreases liver glycogen and causes mild hyperglycaemia in mice.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epinephrine; Glucagon; Hyperglycemia; Liver Glycogen; Male; Mice | 1996 |
A 73-year-old man with hyperglycemia, skin rashes, anemia and weight loss.
Topics: Aged; Anemia; Diagnosis, Differential; Erythema; Glucagon; Glucagonoma; Humans; Hyperglycemia; Male; Pancreatic Neoplasms; Tomography, X-Ray Computed; Weight Loss | 1996 |
Involvement of cerebral neurotensin in hyperglycemic response caused by 2-deoxy-D-glucose in rats.
Topics: Animals; Blood Glucose; Brain; Deoxyglucose; Glucagon; Hyperglycemia; Injections, Spinal; Insulin; Male; Neurotensin; Rats; Rats, Wistar; Time Factors | 1995 |
Glucosamine-induced inhibition of liver glucokinase impairs the ability of hyperglycemia to suppress endogenous glucose production.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucagon; Glucokinase; Glucosamine; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Kinetics; Lactates; Liver; Male; Rats; Rats, Sprague-Dawley; Somatostatin; Uridine Diphosphate Glucose; Uridine Diphosphate N-Acetylglucosamine | 1996 |
A rapid- and short-acting hypoglycemic agent KAD-1229 improves post-prandial hyperglycemia and diabetic complications in streptozotocin-induced non-insulin-dependent diabetes mellitus rats.
Topics: Albuminuria; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Hypoglycemic Agents; Indoles; Insulin; Isoindoles; Male; Pancreas; Rats; Rats, Sprague-Dawley; Streptozocin | 1996 |
Influence of vaginal versus abdominal hysterectomy on perioperative glucose metabolism.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Carbohydrate Metabolism; Deuterium; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Hysterectomy; Hysterectomy, Vaginal; Insulin; Intraoperative Care; Lactates; Liver; Metabolic Clearance Rate; Middle Aged; Norepinephrine; Postoperative Care | 1996 |
The effects of acute hyperglycemia and hyperinsulinemia on plasma leptin levels: its relationships with body fat, visceral adiposity, and age in women.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Aged; Diabetes Mellitus, Type 2; Exercise; Female; Glucagon; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hyperinsulinism; Leptin; Middle Aged; Peptide Fragments; Protein Precursors; Proteins; Weight Loss | 1996 |
Mechanisms of postabsorptive hyperglycemia in streptozotocin diabetic rats.
Topics: Absorption; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Glycogen; Glycosuria; Hyperglycemia; Insulin; Liver; Male; Phlorhizin; Rats; Rats, Wistar; Time Factors | 1996 |
Exhaustion of blood glucose response and enhancement of insulin response after repeated glucagon injections in type-2 diabetes: potentiation by progressive hyperglycemia.
Topics: Aged; Analysis of Variance; B-Lymphocytes; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastrointestinal Agents; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged | 1996 |
Hyperglycemia during childhood diarrhea.
Topics: Blood Glucose; Child; Child, Preschool; Cholera; Dehydration; Diarrhea; Escherichia coli Infections; Female; Glucagon; Humans; Hyperglycemia; Male; Norepinephrine | 1997 |
Melatonin suppresses hyperglycemia caused by intracerebroventricular injection of 2-deoxy-D-glucose in rats.
Topics: Animals; Blood Glucose; Cerebral Ventricles; Deoxyglucose; Glucagon; Hyperglycemia; Injections, Intraperitoneal; Injections, Intraventricular; Insulin; Insulin Secretion; Male; Melatonin; Naphthalenes; Rats; Rats, Wistar | 1997 |
Evidence of increased systemic glucose production and gluconeogenesis in an early stage of NIDDM.
Topics: Alanine; Blood Glucose; Carbon Radioisotopes; Cohort Studies; Diabetes Mellitus, Type 2; Epinephrine; Fasting; Female; Glucagon; Gluconeogenesis; Glucose; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Middle Aged; Reference Values; Tritium | 1997 |
Direct quantification of norepinephrine spillover and hormone output from the pancreas of the conscious dog.
Topics: Animals; Arteries; Blood Glucose; Dogs; Epinephrine; Female; Glucagon; Glucose; Hormones; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Norepinephrine; Pancreas; Pancreatic Polypeptide; Veins | 1997 |
Islet hormone secretion in pancreatic cancer patients with diabetes.
Topics: Adenocarcinoma; Aged; Diabetes Complications; Diabetes Mellitus; Fasting; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Islets of Langerhans; Male; Middle Aged; Pancreatic Hormones; Pancreatic Neoplasms | 1997 |
Studies on the mass action effect of glucose in NIDDM and IDDM: evidence for glucose resistance.
Topics: Adult; Analysis of Variance; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Reference Values; Regression Analysis; Somatostatin | 1997 |
Absence of short-term effects of glucagon-like peptide-1 and of hyperglycemia on plasma leptin levels in man.
Topics: Adult; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Leptin; Male; Osmolar Concentration; Peptide Fragments; Protein Precursors; Proteins | 1997 |
The diabetogenic effects of acute verapamil poisoning.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Female; Glucagon; Glucose; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Antagonists; Male; Sodium Chloride; Verapamil | 1997 |
Diabetes mellitus update.
Topics: Blood Glucose; Dentists; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Epinephrine; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Mouth Diseases; Patient Care Team; Terminology as Topic | 1997 |
Physiological changes in circulating glucagon alter hepatic glucose disposition during portal glucose delivery.
Topics: Animals; Blood Glucose; Dogs; Fasting; Female; Glucagon; Glucose; Hyperglycemia; Hyperinsulinism; Infusions, Intravenous; Insulin; Liver; Male; Models, Biological; Portal System; Somatostatin | 1997 |
Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glucose Transporter Type 3; Homozygote; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monosaccharide Transport Proteins; Nerve Tissue Proteins | 1997 |
Hyperinsulinemia accompanying hyperglycemia in Chinese patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Anabolic Agents; Anemia, Aplastic; Blood Glucose; Female; Glucagon; Glucocorticoids; Glucose Tolerance Test; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Male; Middle Aged; Prednisone; Stanozolol | 1997 |
Leptin--a regulator of islet function?: its plasma levels correlate with glucagon and insulin secretion in healthy women.
Topics: Arginine; Blood Glucose; Body Mass Index; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Middle Aged; Multivariate Analysis; Pancreatic Polypeptide; Postmenopause; Proteins; Sex Characteristics; White People | 1997 |
Effects of glucagon on postprandial carbohydrate metabolism in nondiabetic humans.
Topics: Blood Glucose; C-Peptide; Carbohydrate Metabolism; Female; Food; Gastric Emptying; Gastrointestinal Hormones; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Postprandial Period; Xylose | 1998 |
Influence of muscle glycogen content on metabolic regulation.
Topics: Adult; Bicycling; Blood Glucose; Dietary Carbohydrates; Dietary Fats; Energy Intake; Energy Metabolism; Exercise Test; Glucagon; Glucose Clamp Technique; Glycogen; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Lactates; Male; Muscle Fatigue; Muscle, Skeletal; Oxygen Consumption; Physical Endurance | 1998 |
Preexercise muscle glycogen content affects metabolism during exercise despite maintenance of hyperglycemia.
Topics: Adult; Analysis of Variance; Bicycling; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glycogen; Humans; Hyperglycemia; Kinetics; Lactates; Male; Muscle Fatigue; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Physical Exertion | 1998 |
Insulin secretory capacity and the regulation of glucagon secretion in diabetic and non-diabetic alcoholic cirrhotic patients.
Topics: Adult; Aged; Arginine; Basal Metabolism; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Liver Cirrhosis, Alcoholic; Middle Aged; Secretory Rate | 1998 |
Hormonal counterregulation failure in rats is related to previous hyperglycaemia-hyperinsulinaemia.
Topics: Animals; Blood Glucose; Body Weight; Catecholamines; Eating; Female; Glucagon; Glycerol; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Kinetics; Lactic Acid; Liver; Rats; Rats, Wistar; Secretory Rate | 1998 |
Effects of glycemic control on protective responses against hypoglycemia in type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Norepinephrine; Psychomotor Performance; Reaction Time | 1998 |
Effects of glucagon-like peptide 1 (7-36 amide) on glucose kinetics during somatostatin-induced suppression of insulin secretion in healthy men.
Topics: Adult; Blood Glucose; C-Peptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Male; Peptide Fragments; Proinsulin; Somatostatin | 1998 |
A negative arterial-portal venous glucose gradient decreases skeletal muscle glucose uptake.
Topics: Animals; Blood Glucose; Dogs; Female; Glucagon; Glucose; Hepatic Artery; Hindlimb; Hyperglycemia; Iliac Artery; Iliac Vein; Infusions, Intravenous; Insulin; Liver; Liver Circulation; Male; Muscle, Skeletal; Portal System; Portal Vein; Regional Blood Flow; Somatostatin | 1998 |
Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose Clamp Technique; Glycogen; Glycolysis; Human Growth Hormone; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Middle Aged; Somatostatin; Sulfonylurea Compounds | 1998 |
Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Male; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasodilator Agents | 1998 |
Effect of bilateral lesions of the suprachiasmatic nucleus on hyperglycemia caused by 2-deoxy-D-glucose and vasoactive intestinal peptide in rats.
Topics: Animals; Antimetabolites; Behavior, Animal; Blood Glucose; Circadian Rhythm; Darkness; Denervation; Deoxyglucose; Glucagon; Hyperglycemia; Hypoglycemic Agents; Insulin; Locomotion; Male; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Vasoactive Intestinal Peptide | 1998 |
Synergistic effect of counterregulatory hormones during insulin-induced hypoglycemia in rats: participation of lipolysis and gluconeogenesis to hyperglycemia.
Topics: Animals; Blood Glucose; Drug Synergism; Fasting; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Isoproterenol; Lipolysis; Liver Glycogen; Male; Phenylephrine; Rats; Rats, Wistar | 1996 |
Hormonal and metabolic responses to maintained hyperglycemia during prolonged exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Epinephrine; Exercise; Exercise Test; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glycerol; Hormones; Human Growth Hormone; Humans; Hyperglycemia; Insulin; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Norepinephrine; Oxidation-Reduction | 1999 |
Evidence that the gastrointestinal tract is involved in glucose homeostasis.
Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Dogs; Epinephrine; Female; Gastrointestinal Agents; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Jejunum; Male; Veins | 1996 |
An anti-insulin serum, but not a glucagon antagonist, alters glycemia in fed chickens.
Topics: Animals; Antibodies; Blood Glucose; Blood Proteins; Chickens; Eating; Glucagon; Guinea Pigs; Hormone Antagonists; Hyperglycemia; Insulin; Male; Neutralization Tests | 2000 |
A putative hyperglycemic factor from the cerebral ganglia of Otala lactea (Mollusca: Pulmonata).
Topics: Animals; Cell Extracts; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Activation; Ganglia, Invertebrate; Glucagon; Glucose; Glycogen; Hyperglycemia; Phosphorylases; Snails | 2000 |
Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression.
Topics: Cells, Cultured; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Antagonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osmolar Concentration | 2000 |
Evidence that carotid bodies play an important role in glucoregulation in vivo.
Topics: Animals; Blood Glucose; Blood Pressure; Carotid Body; Dogs; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Homeostasis; Hormones; Hydrocortisone; Hyperglycemia; Hypoglycemia; Infusions, Intravenous; Insulin; Male; Norepinephrine; Time Factors | 2000 |
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Galactose; Glucagon; Glycogen; Human Growth Hormone; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged; Postprandial Period | 2000 |
Degradation and glycemic effects of His(7)-glucitol glucagon-like peptide-1(7-36)amide in obese diabetic ob/ob mice.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Eating; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Mice; Mice, Obese; Oligopeptides; Peptide Fragments; Protease Inhibitors; Protein Precursors; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2001 |
Effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on plasma glucose and glucagon levels of rats.
Topics: Adrenal Medulla; Amphetamines; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Hyperglycemia; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Diabetogenic role of insulin's counterregulatory hormones in the isletectomized, diabetic goby.
Topics: Ammonia; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Fishes; Glucagon; Hydrocortisone; Hyperglycemia; Insulin; Islets of Langerhans; Kinetics; Nitrogen; Rats | 2000 |
Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.
Topics: Aging; Animals; Cataract; Diabetes Mellitus, Type 2; Glucagon; Hyperglycemia; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Pancreas; Proteinuria; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Thirst; Time Factors | 2000 |
Evidence against a rate-limiting role of proinsulin processing for maximal insulin secretion in subjects with impaired glucose tolerance and beta-cell dysfunction.
Topics: Adult; Arginine; Blood Glucose; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Middle Aged; Peptide Fragments; Proinsulin; Protein Precursors | 2001 |
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Peripheral blood mitochondrial DNA content is inversely correlated with insulin secretion during hyperglycemic clamp studies in healthy young men.
Topics: Adult; Anthropometry; C-Peptide; DNA, Mitochondrial; Glucagon; Glucose Clamp Technique; Homeostasis; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Leukocytes; Male; Reference Values | 2001 |
Hepatic insulin expression improves glycemic control in type 1 diabetic rats.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Consensus Sequence; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Furin; Gene Transfer Techniques; Genetic Therapy; Glucagon; Hyperglycemia; Insulin; Islets of Langerhans; Liver; Liver Neoplasms, Experimental; Proinsulin; Protein Precursors; Rats; Rats, Nude; Subtilisins; Transfection | 2001 |
Increased responsiveness to the hyperglycemic, hyperglucagonemic and hyperinsulinemic effects of circulating norepinephrine in ob/ob mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Animals; Blood Glucose; Bromocriptine; Dopamine Agonists; Female; Glucagon; Glucose Clamp Technique; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Mice; Mice, Inbred C57BL; Mice, Obese; Norepinephrine; Random Allocation | 2001 |
Peritoneal implantation of macroencapsulated porcine pancreatic islets in diabetic rats ameliorates severe hyperglycemia and prevents retraction and simplification of hippocampal dendrites.
Topics: Animals; Blood Glucose; Body Weight; C-Peptide; Capsules; Dendrites; Diabetes Mellitus, Experimental; Glucagon; Graft Survival; Hippocampus; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Male; Nerve Degeneration; Peritoneum; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Swine; Treatment Outcome | 2001 |
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Diabetes Mellitus, Type 2; eIF-2 Kinase; Endoplasmic Reticulum; Female; Glucagon; Hyperglycemia; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Pancreas; Phenotype; Phosphorylation; Proinsulin; Protein Biosynthesis; RNA, Messenger; Secretory Vesicles | 2001 |
Pancreatic beta-cells from obese-hyperglycemic mice are characterized by excessive firing of cytoplasmic Ca2+ transients.
Topics: Animals; Caffeine; Calcium; Cytoplasm; Glucagon; Hyperglycemia; Islets of Langerhans; Leptin; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ryanodine; Signal Transduction; Type C Phospholipases | 2001 |
Restored hypoglycemic counterregulation is stable in successful pancreas transplant recipients for up to 19 years after transplantation.
Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Humans; Hyperglycemia; Male; Middle Aged; Pancreas Transplantation; Time Factors; Treatment Outcome | 2001 |
Hyperglycemia compensates for diet-induced insulin resistance in liver and skeletal muscle of rats.
Topics: Analysis of Variance; Animals; Body Weight; Diet; Dietary Fats; Dietary Sucrose; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Starch | 2001 |
Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog.
Topics: Alanine; Animals; Blood Glucose; Dogs; Duodenum; Fructose; Glucagon; Gluconeogenesis; Glucose; Glycerol; Hyperglycemia; Hyperinsulinism; Intestinal Mucosa; Lactic Acid; Liver; Liver Circulation; Osmolar Concentration; Postprandial Period | 2002 |
Glucose kinetics and splanchnic uptake following mixed meal ingestion in cirrhotic-diabetic subjects.
Topics: Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Food; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Kinetics; Lactic Acid; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Splanchnic Circulation | 2001 |
Functional and histochemical analysis on pancreatic islets of APA hamsters with SZ-induced hyperglycemia and hyperlipidemia.
Topics: Animals; Blood Glucose; Cricetinae; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Hyperglycemia; Hyperlipidemias; Immunohistochemistry; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Male; Mesocricetus; Proliferating Cell Nuclear Antigen; Somatostatin; Streptozocin; Vacuoles | 2002 |
Fructose improves the ability of hyperglycemia per se to regulate glucose production in type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Enzyme Activation; Fatty Acids, Nonesterified; Female; Fructose; Glucagon; Glucokinase; Glucose; Human Growth Hormone; Humans; Hyperglycemia; Insulin; Liver; Male; Middle Aged; Somatostatin; Tritium | 2002 |
Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats.
Topics: Animals; Area Under Curve; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Glucagon; Glucose; Glucose Tolerance Test; Glucosides; Hyperglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Rats, Wistar; Terpenes | 2002 |
Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Glucose; Glucose Clamp Technique; Homeostasis; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Male; Norepinephrine; Pancreas; Proglucagon; Protein Precursors; Rats; Rats, Sprague-Dawley; Recurrence; RNA, Messenger; Somatostatin | 2002 |
Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects.
Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glycated Hemoglobin; Glycerol; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Lactates; Liver; Middle Aged; Reference Values; Somatostatin | 2002 |
[Glucide intolerance and its pathogenic mechanisms during parenteral feeding].
Topics: Blood Glucose; Diuresis; Glucagon; Gluconeogenesis; Glycosuria; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Osmolar Concentration; Parenteral Nutrition; Risk | 1977 |
Sympathectomy and prostaglandin deficiency do not prevent gastrogenic hyperglycaemia and hyperinsulinaemia.
Topics: Animals; Blood Glucose; Dogs; Food; Gastrins; Glucagon; Hydrogen-Ion Concentration; Hydroxydopamines; Hyperglycemia; Hyperinsulinism; Indomethacin; Liver Extracts; Prostaglandins; Prostaglandins E; Sympathetic Nervous System | 1979 |
The essential role of glucagon in the pathogenesis of diabetes mellitus.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Growth Hormone-Releasing Hormone; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Pancreatectomy | 1975 |
Letter: Glucagon in pathogenesis of diabetes.
Topics: Animals; Arginine; Diabetes Mellitus; Duodenum; Electrophoresis, Polyacrylamide Gel; Glucagon; Humans; Hyperglycemia; Infusions, Parenteral; Insulin; Pancreas; Swine; Tissue Extracts | 1975 |
Pathogenesis of nonketotic hyperosmolar diabetic coma.
Topics: Animals; Diabetes Mellitus; Diabetic Coma; Fatty Acids, Nonesterified; Glucagon; Glycogen; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Liver; Metabolic Clearance Rate; Osmolar Concentration; Oxidation-Reduction; Rats; Triglycerides | 1975 |
Pancreatectomised man: A model for diabetes without glucagon.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Pancreatectomy | 1976 |
Letter: Diabetes without glucagon.
Topics: Arginine; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Middle Aged; Pancreatectomy; Somatostatin | 1976 |
Influence of somatostatin on carbohydrate disposal and absorption in diabetes mellitus.
Topics: Administration, Oral; Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Drug Evaluation; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Intestinal Absorption; Middle Aged; Somatostatin; Xylose | 1976 |
Effect of lipolytic agents on calcium uptake in the epididymal adipose tissue of obese-hyperglycemic mice and their lean controls [proceedings].
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Epinephrine; Glucagon; Hyperglycemia; Isoproterenol; Lipid Mobilization; Male; Mice; Mice, Obese; Phentolamine; Propranolol; Species Specificity; Theophylline | 1977 |
Diabetes without glucagon.
Topics: Adult; Aged; Diabetes Mellitus; Female; Glucagon; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Male; Middle Aged | 1978 |
Duodenal glucagonoma: a case report.
Topics: Adenoma, Islet Cell; Aged; Bronchopneumonia; Choristoma; Duodenal Neoplasms; Glucagon; Humans; Hyperglycemia; Male; Pancreas; Prostatic Hyperplasia | 1979 |
Effects of intrahepatic transplantation of pancreatic islets on hepatic metabolism in the rat.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Gluconeogenesis; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Liver; Male; Rats; Transplantation, Homologous; Urea | 1978 |
Severe hyperglycemia: effects of rehydration on endocrine derangements and blood glucose concentration.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; C-Peptide; Dehydration; Diabetic Ketoacidosis; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Middle Aged; Norepinephrine; Pancreatic Polypeptide; Parathyroid Hormone; Prolactin | 1979 |
Glucose regulation by isolated near term fetal monkey liver.
Topics: Adenosine Monophosphate; Animals; Animals, Newborn; Female; Fetus; Glucagon; Glucose; Glycogen Synthase; Haplorhini; Hyperglycemia; Hypoglycemia; In Vitro Techniques; Insulin; Liver; Liver Glycogen; Macaca mulatta; Perfusion; Pregnancy; Streptozocin | 1975 |
[The use glucagon for endoscopic and radiological examination of the gastrointestinal tract (author's transl)].
Topics: Endoscopy; Esophagoscopy; Gastrointestinal Diseases; Gastrointestinal Motility; Gastroscopy; Glucagon; Humans; Hyperglycemia; Muscle Tonus; Parasympatholytics; Radiography | 1976 |
[Subacute alcoholic intoxication in rats: effect of an intravenous injection of glucagon or adrenaline].
Topics: Alcoholism; Animals; Blood Glucose; Epinephrine; Ethanol; Glucagon; Humans; Hyperglycemia; Kinetics; Male; Rats | 1978 |
The effect of fasting on tissue cyclic cAMP and plasma glucagon in the obese hyperglycemic mouse.
Topics: Animals; Body Weight; Cyclic AMP; Fasting; Female; Glucagon; Hyperglycemia; Liver Glycogen; Mice; Obesity | 1975 |
The enhancement of adenyl cyclase by steroid therapy in shock.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dogs; Epinephrine; Female; Glucagon; Glucose; Hyperglycemia; Intestines; Liver; Male; Methylprednisolone; Shock, Hemorrhagic; Sodium Fluoride | 1977 |
Lipolysis and cyclic AMP levels in epididymal adipose tissue of obese-hyperglycaemic mice.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Glucagon; Hyperglycemia; Isoproterenol; Kinetics; Male; Mice; Mice, Obese; Secretin; Species Specificity; Vasoactive Intestinal Peptide | 1977 |
Plasma free tryptophan, brain serotonin, and an endocrine profile of the genetically obese hyperglycemic mouse at 4--5 months of age.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Brain; Fasting; Glucagon; Hormones; Hyperglycemia; Insulin; Male; Mice; Mice, Obese; Serotonin; Species Specificity; Thyrotropin; Thyroxine; Triiodothyronine; Tryptophan | 1979 |
Hormonal responses in ethanol-induced hypoglycemia.
Topics: Blood Glucose; Ethanol; Glucagon; Glucose; Growth Hormone; Hormones; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Infusions, Parenteral; Insulin; Male | 1975 |
Osmolar control of the circulation in hemorrhagic hypotension. An experimental study in the cat.
Topics: Adrenal Glands; Animals; Blood Circulation; Blood Glucose; Blood Pressure; Blood Volume; Capillary Permeability; Capillary Resistance; Catecholamines; Cats; Female; Glucagon; Glucose; Hemorrhage; Hydrogen-Ion Concentration; Hyperglycemia; Hypotension; Intestines; Liver; Male; Muscles; Osmolar Concentration; Regional Blood Flow; Skin; Sympathetic Nervous System; Water-Electrolyte Balance | 1975 |
Somatostatinoma.
Topics: Diabetes Mellitus; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pancreatic Neoplasms; Somatostatin | 1977 |
Somatostatin. Its possible role in carbohydrate homeostasis and the treatment of diabetes mellitus.
Topics: Acidosis; Diabetes Mellitus; Fasting; Glucagon; Half-Life; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Somatostatin | 1977 |
Glucagon and insulin binding to liver membranes in a partially nephrectomized uremic rat model.
Topics: Adenylyl Cyclases; Animals; Blood Urea Nitrogen; Cell Membrane; Creatinine; Disease Models, Animal; Glucagon; Glucose; Hyperglycemia; Hyperinsulinism; Hypersensitivity; Insulin; Insulin Resistance; Kidney; Liver; Nephrectomy; Protein Binding; Rats; Uremia | 1977 |
Abnormal alpha cell function in human diabetes: the response to oral protein.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Proteins; Fasting; Female; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Parenteral; Insulin; Islets of Langerhans; Male; Middle Aged | 1978 |
Segmental pancreatic transplantation in pigs.
Topics: Animals; Cyclophosphamide; Glucagon; History, 18th Century; Hyperglycemia; Ligation; Methylprednisolone; Pancreas; Pancreas Transplantation; Pancreatectomy; Pancreatic Ducts; Peritoneum; Swine; Time Factors; Transplantation, Homologous | 1979 |
[Effect of ambient temperature on pancreatic hormone secretions at birth].
Topics: Animals; Animals, Newborn; Female; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Phentolamine; Pregnancy; Rats; Temperature | 1979 |
Somatostatin does not cause sustained fasting hyperglycemia in man.
Topics: Adult; Blood Glucose; Dose-Response Relationship, Drug; Fasting; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Somatostatin | 1979 |
[Etiology of congenital transitory hyperglycemia].
Topics: Blood Glucose; Glucagon; Growth Hormone; Humans; Hyperglycemia; Infant; Insulin; Islets of Langerhans; Male | 1979 |
Role of glucagon in diabetes.
Topics: Antigens; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Extracellular Space; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Models, Biological | 1977 |
Hyperglycemia and glucagon suppression: possible importance of the vagus and enteric humoral factors.
Topics: Adult; Atropine; Blood Glucose; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Vagus Nerve | 1979 |
Hyperglycemia per se (insulin and glucagon withdrawn) can inhibit hepatic glucose production in man.
Topics: Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver; Male; Somatostatin | 1979 |
Somatostatin: central nervous system actions on glucoregulation.
Topics: Animals; Atropine; Blood Glucose; Bombesin; Central Nervous System; Endorphins; Glucagon; Hormones; Hyperglycemia; Insulin; Kinetics; Male; Peptides; Rats; Somatostatin; Structure-Activity Relationship | 1979 |
Neural release of glucagon is inhibited by hyperglycemia and enhanced by phentolamine.
Topics: Animals; Dogs; Duodenum; Glucagon; Hyperglycemia; Pancreas; Perfusion; Phentolamine; Splanchnic Nerves; Stomach | 1979 |
Pancreatic alpha- and beta-cell responses to GIP infusion in normal man.
Topics: Adult; Blood Glucose; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Male | 1979 |
Central nervous system action of bombesin: mechanism to induce hyperglycemia.
Topics: Adrenal Glands; Animals; Blood Glucose; Bombesin; Brain; Epinephrine; Glucagon; Hyperglycemia; Insulin; Liver; Male; Peptides; Pituitary Gland; Rats; Somatostatin | 1979 |
[Behavior of glucagonemia in hyperglycemia and hypoglycemia conditions provoked in obese children by means of oral load of normal and pathological doses of glucose].
Topics: Age Factors; Child; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemia; Injections, Intravenous; Insulin; Male; Obesity | 1979 |
Gluconeogenesis in the burned patient.
Topics: Burns; Glucagon; Glucocorticoids; Gluconeogenesis; Humans; Hyperglycemia; Insulin | 1979 |
Glucose homoeostasis following injury.
Topics: Glucagon; Glucose; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Hyperglycemia; Insulin; Nitrogen; Norepinephrine; Potassium; Surgical Procedures, Operative; Wounds and Injuries | 1979 |
Glucagon antiserum: a tool to investigate the role of circulating glucagon in obese-hyperglycaemic (ob/ob) mice [proceedings].
Topics: Animals; Blood Glucose; Glucagon; Hyperglycemia; Immune Sera; Insulin; Mice; Mice, Obese | 1979 |
Possible mechanism by which somatostatin-induced glucagon suppression improves glucose tolerance during insulinopaenia in man.
Topics: Adolescent; Adult; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Somatostatin | 1979 |
[Late hypoglycaemia in chemical diabetes. Abnormalities of pancreatic glucagon secretion and effect of pectine (author's transl)].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemia; Male; Middle Aged; Pectins | 1979 |
Plasma insulin and glucose responses to glucagon and catecholamines in the European silver eel (Anguilla anguilla L).
Topics: Animals; Arginine; Blood Glucose; Eels; Epinephrine; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Norepinephrine; Portal Vein; Regional Blood Flow | 1977 |
Bombesin affects the central nervous system to produce hyperglycemia in rats.
Topics: Animals; Blood Glucose; Body Temperature; Bombesin; Central Nervous System; Glucagon; Hyperglycemia; Insulin; Male; Peptides; Rats; Structure-Activity Relationship | 1977 |
Hyperglycemia, hypoinsulinemia, and hyperglucagonemia in acute water intoxication.
Topics: Acute Disease; Animals; Glucagon; Hyperglycemia; Hyponatremia; Insulin; Mice; Water Intoxication | 1978 |
Metabolic response in shock.
Topics: Acidosis; Animals; Blood Glucose; Blood Volume; Catecholamines; Dogs; Fatty Acids, Nonesterified; Glucagon; Glucose; Hyperglycemia; Hypoglycemia; Insulin; Lactates; Oxygen Consumption; Shock; Shock, Septic; Triglycerides | 1978 |
Plasma glucose, insulin, glucagon, and growth hormone in kindreds with maturity-onset type of hyperglycemia in young people.
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Pedigree | 1978 |
Neurotensin hyperglycemia:evidence for histamine mediation and the assessment of a possible physiologic role.
Topics: Animals; Blood Glucose; Cimetidine; Diphenhydramine; Glucagon; Histamine; Hyperglycemia; Insulin; Male; Neurotensin; Rats | 1978 |
Lithium in diabetes mellitus: a paradoxical response.
Topics: Bipolar Disorder; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Glucagon; Humans; Hyperglycemia; Insulin; Lithium; Male; Middle Aged | 1978 |
Somatostatin: central nervous system (CNS) action on glucoregulation.
Topics: Animals; Blood Glucose; Bombesin; Central Nervous System; Glucagon; Hyperglycemia; Insulin; Male; Peptide Fragments; Rats; Somatostatin | 1978 |
Effect of glucagon on glucose production during insulin deficiency in the dog.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Female; Glucagon; Gluconeogenesis; Hyperglycemia; Insulin; Lactates; Male; Somatostatin; Time Factors | 1978 |
[Pancreatic glucagon and the pathogenesis of diabetes mellitus (author's transl)].
Topics: Adult; Diabetes Mellitus; Fasting; Female; Glucagon; Humans; Hyperglycemia; Male; Middle Aged; Pancreas; Pancreatectomy; Time Factors | 1978 |
[The acute effect of the human growth hormone under hyperglycemic conditions in man (author's transl)].
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Insulin; Male | 1978 |
Failure of somatostatin to decrease blood glucose by suppression of extrapancreatic glucagon in severely diabetic depancreatized dogs.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dogs; Glucagon; Hyperglycemia; Insulin; Pancreatectomy; Somatostatin | 1978 |
Essential roles of insulin and glucagon in regulating glucose fluxes during exercise in dogs.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucose; Hyperglycemia; Hypoglycemia; Insulin; Muscles; Pancreatectomy; Physical Exertion | 1979 |
Synergistic interactions of physiologic increments of glucagon, epinephrine, and cortisol in the dog: a model for stress-induced hyperglycemia.
Topics: Animals; Blood Glucose; Disease Models, Animal; Dogs; Drug Synergism; Epinephrine; Glucagon; Hydrocortisone; Hyperglycemia; Male; Stress, Physiological | 1979 |
Somatostatin--clinical implications.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Digestive System; Gastric Mucosa; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Pancreas; Rats; Somatostatin | 1976 |
Alpha cell function in diabetes mellitus.
Topics: Arginine; Diabetes Mellitus; Eating; Epinephrine; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Somatostatin | 1976 |
Current aspects of aetiology and diagnosis in diabetes mellitus.
Topics: Adult; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Histocompatibility Antigens; Humans; Hyperglycemia; Islets of Langerhans; Somatostatin; Virus Diseases | 1976 |
[Regulation of pancreatic glucagon secretion].
Topics: Amino Acids; Animals; Carbohydrate Metabolism; Deoxyglucose; Diabetes Mellitus; Fatty Acids; Glucagon; Gluconeogenesis; Hexoses; Hyperglycemia; Islets of Langerhans; Ketone Bodies; Mannoheptulose; Mice; Pancreas; Rats | 1976 |
Histophysiology of the pancreatic islets of Rana tigrina, treated with glucagon.
Topics: Animals; Anura; Blood Glucose; Glucagon; Hyperglycemia; India; Islets of Langerhans; Ranidae | 1976 |
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon.
Topics: Adult; Alanine; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Insulin; Ketone Bodies; Lactates; Male; Peptides; Substance Withdrawal Syndrome | 1975 |
[The historic role of insulin in the physiopathology of the metabolic complications from pancreatic diabetes. Therapeutic implications for somatostatin].
Topics: Adult; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1975 |
Discordance of diabetic microangiopathy in identical twins.
Topics: Adult; Basement Membrane; Blood Glucose; Capillaries; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Ketoacidosis; Diseases in Twins; Female; Glucagon; Humans; Hyperglycemia; Hypertrophy; Muscles; Pregnancy; Twins; Twins, Monozygotic | 1976 |
The emergency management of the diabetic at home.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Ketoacidosis; Emergencies; First Aid; Glucagon; Glucose; Home Nursing; Humans; Hyperglycemia; Hypoglycemia; Insulin; Vomiting | 1976 |
Postoperative tolerance to glucose and sugar substitutes.
Topics: Adult; Female; Fructose; Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Parenteral Nutrition; Postoperative Care; Xylitol | 1976 |
Dose response to insulin in man: differential effects on glucose and ketone body regulation.
Topics: Adult; Bicarbonates; Blood Glucose; Dexamethasone; Diabetes Mellitus; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Ketone Bodies; Middle Aged; Potassium | 1977 |
Immunoreactive glucagon levels in obese-hyperglycemic (ob/ob) mice.
Topics: Animals; Arginine; Blood Glucose; Drug Synergism; Fasting; Glucagon; Glucose; Hyperglycemia; Insulin; Male; Mice; Mice, Obese; Obesity; Phenotype | 1977 |
Transient diabetes mellitus in a neonate. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion.
Topics: Adolescent; Antigens; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Parenteral; Insulin; Insulin Secretion; Pregnancy; Somatostatin; Theophylline; Time Factors; Tolbutamide | 1977 |
Effects of glucagon and secretin on food- or morphine-induced motor activity of the distal colon, rectum, and anal sphincter.
Topics: Adult; Aged; Anal Canal; Colon; Female; Food; Gastrointestinal Motility; Glucagon; Humans; Hyperglycemia; Intestine, Large; Male; Middle Aged; Morphine; Muscles; Rectum; Secretin | 1977 |
On the mechanism of diazoxide-induced hyperglycemia.
Topics: Animals; Blood Glucose; Diazoxide; Dogs; Glucagon; Hyperglycemia; Insulin; Phentolamine; Somatostatin | 1977 |
Adenylate cyclase activity in hepatic plasma membranes from obese-hyperglycaemic mice [proceedings].
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hyperglycemia; Liver; Mice; Mice, Obese | 1977 |
Does glucagon play a role in the insulin resistance of patients with adult non-ketotic diabetes?
Topics: Adult; Blood Glucose; Diabetes Mellitus; Fasting; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Resistance; Middle Aged | 1977 |
Influence of glucagon replacement on the hyperglycemic and hyperketonemic response to prolonged somatostatin infusion in normal man.
Topics: Adult; Blood Glucose; Female; Glucagon; Humans; Hyperglycemia; Insulin; Ketones; Male; Somatostatin | 1977 |
Insulin and jejunal electrical activity in dogs and sheep.
Topics: Animals; Arginine; Blood Glucose; Dogs; Fatty Acids, Volatile; Female; Gastrointestinal Motility; Glucagon; Glucose; Hyperglycemia; Insulin; Jejunum; Leucine; Male; Membrane Potentials; Milk; Sheep; Vagotomy; Vagus Nerve | 1976 |
Hyperglycemia and hyperglucagonemia following neurotensin administration.
Topics: Adrenal Medulla; Animals; Dose-Response Relationship, Drug; Glucagon; Hyperglycemia; Hypothalamus; Injections, Intra-Arterial; Injections, Intraventricular; Insulin; Male; Nerve Tissue Proteins; Phentolamine; Propranolol; Rats; Somatostatin | 1976 |
[Hepatic participation in the regulation of glucides: blocking action of glucagon on hepatic utilization of insulin].
Topics: Animals; Dogs; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver; Liver Glycogen | 1976 |
Hormonal responses and their effect on metabolism.
Topics: Adolescent; Adult; Body Temperature Regulation; Burns; Catecholamines; Energy Metabolism; Energy Transfer; Glucagon; Glucocorticoids; Growth Hormone; Homeostasis; Hormones; Humans; Hyperglycemia; Insulin; Middle Aged; Nitrogen; Oxygen Consumption; Stress, Physiological; Wound Infection | 1976 |
Editorial: The primacy of insulin.
Topics: Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Insulin; Somatostatin | 1976 |
Gastric A-cell function in insulin-deprived depancreatized dogs.
Topics: Animals; Arginine; Dogs; Gastric Mucosa; Glucagon; Hyperglycemia; Ileum; Insulin; Jejunum; Pancreatectomy | 1976 |
Insulin, glucagon, and somatostatin in normal physiology and diabetes mellitus.
Topics: Carbohydrate Metabolism; Diabetes Mellitus; Dietary Proteins; Digestive System; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver; Somatostatin | 1976 |
Hyperglycemia induced by somatostatin in normal subjects.
Topics: Adult; Glucagon; Humans; Hyperglycemia; Insulin; Male; Somatostatin; Time Factors | 1976 |
Somatostatin and diabetes mellitus: the role of glucagon in diabetic hyperglycemia and glucose intolerance.
Topics: Diabetes Mellitus; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Somatostatin | 1976 |
A current concept of the pathophysiology of the hyperglycemia of diabetes mellitus.
Topics: Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion | 1976 |
Glucagon: role in the hyperglycemia of diabetes mellitus.
Topics: Animals; Arginine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Glucagon; Growth Hormone-Releasing Hormone; Hyperglycemia; Insulin; Oligopeptides; Pancreatectomy | 1975 |
Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Synergism; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Islets of Langerhans; Male; Middle Aged; Phentolamine; Propranolol; Somatostatin | 1976 |
Permanent neonatal diabetes mellitus: a case report with plasma insulin studies.
Topics: Blood Glucose; Chronic Disease; Diabetes Mellitus; Drug Tolerance; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Male; Tolbutamide | 1975 |
Hormonal control of ketogenesis. Rapid activation of hepatic ketogenic capacity in fed rats by anti-insulin serum and glucagon.
Topics: Animals; Blood Glucose; Carnitine O-Acetyltransferase; Fasting; Fatty Acids, Nonesterified; Glucagon; Hyperglycemia; Infusions, Parenteral; Insulin; Insulin Antibodies; Ketone Bodies; Liver; Liver Glycogen; Male; Oleic Acids; Rats | 1975 |
Conditioning insulin effects.
Topics: Animals; Association; Behavior, Animal; Blood Glucose; Conditioning, Classical; Cues; Depression, Chemical; Extinction, Psychological; Glucagon; Hyperglycemia; Hypoglycemia; Injections, Intraperitoneal; Insulin; Male; Motor Activity; Physical Stimulation; Placebos; Rats; Seizures; Smell | 1975 |
Arginine-stimulated acute phase of insulin and glucagon secretion. I. in normal man.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Male | 1975 |
Gastric operations and glucose homeostasis. II. glucagon and secretin.
Topics: Adult; Antigens; Blood Glucose; Duodenal Ulcer; Gastrectomy; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Middle Aged; Postoperative Complications; Pyloric Antrum; Secretin; Vagotomy | 1975 |
Metabolic actions of vasopressin, glucagon and adrenalin in the intact rat.
Topics: Adipose Tissue; Animals; Blood Glucose; Epinephrine; Fatty Acids; Female; Glucagon; Glycogen; Hyperglycemia; Insulin; Liver; Male; Muscles; Phosphorylases; Rats; Vasopressins | 1975 |
The role of glucagon in the pathogenesis of the endogenous hyperglycemia of diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; Dogs; Glucagon; Hyperglycemia; Pancreas; Pancreatectomy; Somatostatin | 1975 |
[Induced hyperglycemia and its relationship to underweight fetuses: study on a newborn infant].
Topics: Birth Weight; Blood Glucose; Female; Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Infant, Newborn; Insulin; Pregnancy | 1975 |
Letter: Correction of heart failure with treatment of hyperglycemia.
Topics: Animals; Catecholamines; Dogs; Glucagon; Heart Failure; Humans; Hyperglycemia; Insulin; Myocardial Contraction; Rabbits | 1976 |
Interaction of somatostatin, glucagon, and insulin on hepatic glucose output in the normal dog.
Topics: Animals; Blood Glucose; Dogs; Drug Synergism; Glucagon; Glucose; Hyperglycemia; Hypoglycemia; Insulin; Liver; Somatostatin | 1976 |
Glucagon and insulin relationships in the obese hyperglycemic mouse (ob/ob).
Topics: Animals; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Male; Mice; Mice, Obese | 1976 |
Altered insulin and glucagon secretion in treated genetic hyperlipemia: a mechanism of theraphy?
Topics: Animals; Arginine; Blood Glucose; Disease Models, Animal; Glucagon; Glycolates; Halofenate; Hyperglycemia; Hyperlipidemias; Insulin; Rats; Rats, Inbred Strains | 1976 |
Studies on the hyperglycemic effect of diphenylhydantoin in normal golden hamsters.
Topics: Animals; Blood Glucose; Cricetinae; Glucagon; Hyperglycemia; Insulin; Male; Phentolamine; Phenytoin; Propranolol; Reserpine | 1976 |
Effects of mild-to-moderate hyperglycaemia per se on glucose production and uptake in the elderly.
Topics: Adult; Age Factors; Aged; Blood Glucose; C-Peptide; Glucagon; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Metabolic Clearance Rate; Severity of Illness Index; Time Factors | 1992 |
Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs.
Topics: Animals; Dogs; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Hyperglycemia; Insulin; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Pancreas | 1992 |
Evidence that GLUT-2 mRNA and protein concentrations are decreased by hyperinsulinaemia and increased by hyperglycaemia in liver of diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression; Glucagon; Glucokinase; Hyperglycemia; Insulin; Liver; Male; Monosaccharide Transport Proteins; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; RNA, Messenger | 1992 |
Analysis of early-phase insulin responses in nonobese subjects with mild glucose intolerance.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Reference Values | 1992 |
Effect of high carbohydrate intake on hyperglycemia, islet function, and plasma lipoproteins in NIDDM.
Topics: Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Fatty Acids, Monounsaturated; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Lipoproteins; Male; Middle Aged; Triglycerides | 1992 |
Plasma islet amyloid polypeptide levels in obesity, impaired glucose tolerance and non-insulin-dependent diabetes mellitus.
Topics: Adult; Amyloid; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Islet Amyloid Polypeptide; Male; Middle Aged; Obesity; Radioimmunoassay; Reference Values | 1992 |
Mechanism of intrahippocampal neostigmine-induced hyperglycemia in fed rats.
Topics: Animals; Epinephrine; Glucagon; Hippocampus; Hyperglycemia; Hypothalamus, Middle; Insulin; Insulin Secretion; Male; Neostigmine; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Glucose homeostasis. Comparison between hypothermic and normothermic cardiopulmonary bypass.
Topics: Adult; Aged; Blood Glucose; Cardiopulmonary Bypass; Coronary Artery Bypass; Epinephrine; Female; Glucagon; Growth Hormone; Heart Valves; Homeostasis; Humans; Hydrocortisone; Hyperglycemia; Hypothermia, Induced; Insulin; Male; Middle Aged; Norepinephrine; Prospective Studies | 1992 |
Encainide-induced diabetes: analysis of islet cell function.
Topics: Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet; Encainide; Glucagon; Humans; Hyperglycemia; Insulin Resistance; Islets of Langerhans; Male | 1992 |
Failure of chronic hyperinsulinemia to suppress pancreatic glucagon in vivo in the rat.
Topics: Animals; Blood Glucose; Body Weight; Chronic Disease; Glucagon; Hyperglycemia; Hyperinsulinism; Insulin; Male; Pancreas; Rats; Rats, Inbred Strains; Somatostatin; Sucrose | 1991 |
Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.
Topics: Alloxan; Animals; Arginine; Dogs; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Somatostatin | 1991 |
Relative contribution of nervous system and hormones to hyperglycemia induced by thyrotropin-releasing hormone in fed rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Brain; Epinephrine; Glucagon; Hepatic Veins; Hormones; Hyperglycemia; Injections, Intraventricular; Insulin; Liver; Male; Norepinephrine; Rats; Rats, Inbred Strains; Somatostatin; Thyrotropin-Releasing Hormone | 1991 |
Nickel-induced hyperglycaemia: the role of insulin and glucagon.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Glycogen; Homeostasis; Hyperglycemia; Injections, Intraperitoneal; Insulin; Liver; Nickel; Radioimmunoassay; Rats; Rats, Inbred Strains | 1992 |
Glutathione infusion potentiates glucose-induced insulin secretion in aged patients with impaired glucose tolerance.
Topics: Aged; Blood Glucose; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Glutathione; Humans; Hyperglycemia; Insulin; Insulin Secretion; Time Factors | 1992 |
Hyperglycaemia but not hyperinsulinaemia prevents the secretion of glucagon-like peptide-1 (7-36 amide) stimulated by fat ingestion.
Topics: Adult; Analysis of Variance; Blood Glucose; Chromatography, Gel; Dietary Fats; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Peptide Fragments; Peptides | 1991 |
Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulinoma; Male; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1991 |
Glucose overload and hepatic energy metabolism after resection of the cirrhotic liver in rats.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Dietary Carbohydrates; Energy Intake; Energy Metabolism; Fatty Acids; Glucagon; Glucose; Hepatectomy; Hyperglycemia; Liver; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; Palmitic Acid; Palmitic Acids; Postoperative Period; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Postprandial hyperglycemia and pancreatic function in cystic fibrosis patients.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Cystic Fibrosis; Eating; Female; Forced Expiratory Flow Rates; Gastric Inhibitory Polypeptide; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Reference Values; Time Factors | 1991 |
Attenuated anomeric difference of glucose-induced insulin release in the perfused pancreas of diazoxide-treated rats.
Topics: Administration, Oral; Animals; Diazoxide; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Pancreas; Rats; Rats, Inbred Strains | 1991 |
Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice.
Topics: Administration, Oral; Animals; Blood Glucose; Chromans; Diabetes Mellitus; Glucagon; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Pancreas; Thiazoles; Thiazolidinediones; Troglitazone | 1991 |
Supplemental-chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets.
Topics: Adult; Aged; Blood Glucose; Chromium; Diet; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Middle Aged | 1991 |
The amino acid-induced alteration in renal hemodynamics is glucagon independent.
Topics: Amino Acids; Animals; Dogs; Fasting; Glucagon; Glucose Clamp Technique; Hemodynamics; Hyperglycemia; Insulin; Renal Circulation | 1991 |
Lack of effect of hyperglycemia on lipolysis in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Lipolysis; Male; Palmitic Acid; Palmitic Acids; Reference Values; Somatostatin | 1990 |
Contribution to postprandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Kinetics; Liver; Male; Middle Aged; Splanchnic Circulation; Time Factors | 1991 |
Pancreatic endocrine function in cystic fibrosis.
Topics: Adult; Arginine; C-Peptide; Cystic Fibrosis; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemia; Insulin; Pancreas; Pancreatic Polypeptide; Time Factors | 1991 |
The effect of acute hyperglycemia on the plasma C-peptide response to intravenous glucagon or to a mixed meal in insulin-dependent diabetes mellitus.
Topics: Acute Disease; Adolescent; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Food; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Islets of Langerhans; Male | 1991 |
[Stress and glycemic control in diabetes mellitus].
Topics: Blood Glucose; Catecholamines; Diabetes Mellitus; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Stress, Psychological | 1991 |
Ischemia in normoglycemic and hyperglycemic rats: plasma energy substrates and hormones.
Topics: Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Corticosterone; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Hormones; Hyperglycemia; Insulin; Ischemic Attack, Transient; Ketone Bodies; Male; Norepinephrine; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains | 1990 |
'Diabetic' emergencies. They happen with or without diabetes.
Topics: Blood Glucose; Diabetic Ketoacidosis; Diagnosis, Differential; Emergencies; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemia; Insulin; Sodium Chloride; Sulfonylurea Compounds | 1990 |
Early morning hyperglycaemia "dawn phenomenon" in non-insulin dependent diabetes mellitus (NIDDM): effects of cortisol suppression by metyrapone.
Topics: Aged; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glycated Hemoglobin; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Metyrapone; Norepinephrine | 1990 |
Postprandial hyperglycaemia following a morning hypoglycaemia in type 1 diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Eating; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male | 1990 |
Acute changes in plasma non-esterified fatty acid concentration do not change hepatic glucose production in people with type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Lipids; Liver; Male; Middle Aged; Niacin; Safflower Oil | 1990 |
Maintenance of pancreatic endocrine B cells of neonatal rat: Part-XIV--Effect of maternal hyperglycemia on the secretion of insulin and glucagon.
Topics: Animals; Animals, Newborn; Cells, Cultured; Female; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pregnancy; Pregnancy in Diabetics; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1990 |
Failure of nocturnal hypoglycemia to cause daytime hyperglycemia in patients with IDDM.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Hypoglycemia; Insulin; Lactates; Male; Norepinephrine | 1990 |
Hyperglycemia per se can reduce plasma free fatty acid and glycerol levels in the acutely insulin-deficient dog.
Topics: Acute Disease; Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Hyperglycemia; Insulin; Male; Osmolar Concentration | 1990 |
[Consequences of hyperglycemia on glucose and nitrogen metabolism in liver cirrhosis. A study using a hyperglycemic clamp].
Topics: Adult; Aged; Amino Acids; Ammonia; C-Peptide; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitrogen | 1990 |
Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age.
Topics: 3-Hydroxybutyric Acid; Adult; Age Factors; Aged; Aging; Blood Glucose; C-Peptide; Drug Administration Schedule; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Hydroxybutyrates; Hyperglycemia; Infusions, Intravenous; Insulin; Ketone Bodies; Kinetics; Lipolysis; Reference Values | 1990 |
Actions of novel antidiabetic agent englitazone in hyperglycemic hyperinsulinemic ob/ob mice.
Topics: 3-Hydroxybutyric Acid; Animals; Benzopyrans; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Glucagon; Glycerol; Hydroxybutyrates; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Reference Values; Thiazoles; Thiazolidinediones; Triglycerides | 1990 |
No change of beta-endorphin plasma levels during hyperglycemic glucose clamping in obese patients and lean controls.
Topics: Adult; beta-Endorphin; Body Mass Index; Female; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Obesity | 1990 |
Impaired hepatic glycogenolysis related to hyperinsulinemia in newborns from hyperglycemic pregnant rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Female; Glucagon; Hyperglycemia; Hyperinsulinism; Insulin; Liver Glycogen; Maternal-Fetal Exchange; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Inbred Strains | 1990 |
Galanin-induced hyperglycemia: effect on insulin and glucagon.
Topics: Animals; Catecholamines; Dogs; Dose-Response Relationship, Drug; Galanin; Glucagon; Growth Hormone; Hydrocortisone; Hyperglycemia; Insulin; Male; Peptides; Time Factors | 1986 |
The relative importance of nervous system and hormones to the 2-deoxy-D-glucose-induced hyperglycemia in fed rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Deoxy Sugars; Deoxyglucose; Epinephrine; Glucagon; Hepatic Veins; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Liver; Male; Nervous System; Norepinephrine; Rats; Rats, Inbred Strains; Somatostatin; Sympathetic Nervous System | 1989 |
Assessment of pancreatic islet-cell population in the hyperglycemic athymic nude mouse: immunohistochemical, ultrastructural, and hormonal studies.
Topics: Animals; Blood Glucose; Cell Count; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Mice, Nude; Microscopy, Electron; Radioimmunoassay; Somatostatin | 1989 |
Central nervous system control of glycogenolysis and gluconeogenesis in fed and fasted rat liver.
Topics: Adrenal Medulla; Animals; Blood Glucose; Cerebral Ventricles; Epinephrine; Fasting; Glucagon; Gluconeogenesis; Glycogen; Hyperglycemia; Insulin; Liver; Male; Neostigmine; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylases; Rats; Rats, Inbred Strains; Somatostatin; Time Factors | 1989 |
Involvement of adrenergic mechanism in hyperglycemia due to SCN stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System; Electric Stimulation; Female; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperglycemia; Insulin; Propranolol; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Suprachiasmatic Nucleus; Yohimbine | 1989 |
Galanin inhibits insulin secretion and induces hyperglycemia in dogs.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Dogs; Fasting; Galanin; Gastric Inhibitory Polypeptide; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Pancreatic Polypeptide; Peptides | 1985 |
Hyperglycemia may determine fibrinopeptide A plasma level increase in humans.
Topics: Adult; Blood Glucose; Fibrinogen; Fibrinopeptide A; Glucagon; Glucose; Heparin; Humans; Hyperglycemia; Infusions, Intravenous; Male; Thrombin; Time Factors | 1989 |
Estimates of in vivo insulin action in man: comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies.
Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Female; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Insulin Resistance; Male; Norepinephrine; Obesity | 1989 |
Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry.
Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; Genes; Glucagon; Glucose; Glucose Clamp Technique; Homeostasis; Hyperglycemia; Islets of Langerhans; Mice; Mice, Obese; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Probes; Pancreatectomy; Proglucagon; Proinsulin; Protein Precursors; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger | 1989 |
Insulin and glucagon secretion are suppressed equally during both hyper- and euglycemia by moderate hyperinsulinemia in patients with diabetes mellitus.
Topics: Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged | 1989 |
Pancreatic hormonal responses to hyperglycemia during orthotopic liver transplantation in man.
Topics: Blood Glucose; Glucagon; Humans; Hyperglycemia; Insulin; Liver Transplantation; Pancreas | 1989 |
Alloxan-induced diabetes mellitus in the pregnant ewe: metabolic and cardiovascular effects on the mother and her fetus.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Fetal Hypoxia; Glucagon; Hyperglycemia; Hyperinsulinism; Insulin; Ketone Bodies; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy in Diabetics; Sheep; Sheep Diseases | 1989 |
Responses of the pancreatic A cell during hypoglycemia and hyperglycemia are dependent on the B cell.
Topics: Animals; Arginine; Glucagon; Glucose; Hyperglycemia; Hypoglycemia; Insulin; Islets of Langerhans; Male; Pancreas; Papio | 1989 |
Early morning hyperglycemia in insulin-dependent diabetes: acute and sustained effects of cholinergic blockade.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Male; Parasympatholytics; Pirenzepine | 1989 |
Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans.
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucagon; Gluconeogenesis; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Liver; Male; Reference Values | 1989 |
Preservation of pancreatic beta cell function with pulsatile cardiopulmonary bypass.
Topics: Blood Glucose; C-Peptide; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Glucagon; Humans; Hyperglycemia; Insulin; Intraoperative Care; Islets of Langerhans; Lactates; Lactic Acid; Male; Middle Aged; Pulsatile Flow | 1989 |
Role of glucagon in hyperglycemic response during a short period of hemorrhage in anesthetized dogs.
Topics: Adrenalectomy; Animals; Catecholamines; Dogs; Glucagon; Hyperglycemia; Insulin; Male; Pancreas; Shock, Hemorrhagic | 1989 |
The plasma C-peptide and insulin responses to stimulation with intravenous glucagon and a mixed meal in well-controlled type 2 (non-insulin-dependent) diabetes mellitus: dependency on acutely established hyperglycaemia.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Time Factors | 1989 |
Autonomic and endocrine participation in opioid peptide-induced hyperglycemia.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cisterna Magna; Corticosterone; Dopamine; Epinephrine; Glucagon; Growth Hormone; Hyperglycemia; Injections, Intra-Arterial; Injections, Intraventricular; Insulin; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1987 |
Hyperglycaemic effect of glucagon administered intracerebroventricularly in the rat.
Topics: Adrenalectomy; Animals; Atropine; Autonomic Nervous System; Blood Glucose; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperglycemia; Injections, Intravenous; Injections, Intraventricular; Insulin; Male; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1985 |
Prolonged hyperglycaemia during infusion of glucose and somatostatin impairs pancreatic A- and B-cell responses to decrements in plasma glucose in normal man: evidence for induction of altered sensitivity to glucose.
Topics: Adult; Blood Glucose; C-Peptide; Drug Resistance; Epinephrine; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Islets of Langerhans; Male; Somatostatin; Time Factors | 1985 |
Pathogenesis of the dawn phenomenon in patients with insulin-dependent diabetes mellitus. Accelerated glucose production and impaired glucose utilization due to nocturnal surges in growth hormone secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Growth Hormone; Humans; Hyperglycemia; Insulin; Male; Norepinephrine; Phentolamine; Propranolol; Somatostatin; Time | 1985 |
Effects of insulin on fasting and meal-stimulated somatostatin-like immunoreactivity in noninsulin-dependent diabetes mellitus: evidence for more than one mechanism of action.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Eating; Fasting; Feedback; Female; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Male; Middle Aged; Somatostatin | 1986 |
[Hyperglycemic agents].
Topics: Blood Glucose; Chemical Phenomena; Chemistry; Diazoxide; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Somatostatin; Streptozocin | 1986 |
Islets of Langerhans in adolescents and adults with cystic fibrosis. A quantitative study.
Topics: Adolescent; Adult; Age Factors; Child; Cystic Fibrosis; Diabetes Mellitus, Type 1; Female; Glucagon; Humans; Hyperglycemia; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Male; Somatostatin | 1986 |
Increase in plasma glucose concentration after intracerebroventricular injection of N,O'-dibutyryl cyclic adenosine 3',5'-monophosphate.
Topics: Adenosine Triphosphate; Animals; Atropine; Blood Glucose; Bucladesine; Cyclic AMP; Dibutyryl Cyclic GMP; Epinephrine; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperglycemia; Injections, Intraventricular; Male; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Somatostatin | 1986 |
The influence of graded hyperglycemia with and without physiological hyperinsulinemia on forearm glucose uptake and other metabolic responses in man.
Topics: Adult; Blood Glucose; Forearm; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Parenteral; Insulin; Male; Somatostatin | 1986 |
Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Liver; Middle Aged; Somatostatin | 1987 |
Pancreatic somatostatin is a mediator of glucagon inhibition by hyperglycemia.
Topics: Animals; Dogs; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Pancreas; Somatostatin | 1987 |
Basal and meal-induced somatostatin-like immunoreactivity in healthy subjects and in IDDM and totally pancreatectomized patients. Effects of acute blood glucose normalization.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Female; Gastric Inhibitory Polypeptide; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Pancreatectomy; Somatostatin | 1987 |
The effects of hyperglycaemia on isotopic measurement of glucose utilisation using [2(3)H], [3(3)H] and [6(14)C] glucose in patients with type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Hyperglycemia; Insulin; Kinetics; Male; Radioisotope Dilution Technique; Reference Values; Somatostatin; Tritium | 1987 |
Hyperglycemia induced by electrical stimulation of lateral part of dorsal parabrachial nucleus.
Topics: Animals; Atropine; Blood Glucose; Electric Stimulation; Female; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Suprachiasmatic Nucleus | 1988 |
Relative contributions of the nervous system and hormones to CNS-mediated hyperglycemia.
Topics: Adrenal Medulla; Animals; Blood Glucose; Cerebral Ventricles; Epinephrine; Glucagon; Hyperglycemia; Injections, Intraventricular; Insulin; Male; Neostigmine; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values; Somatostatin | 1988 |
Time-dependent involvement of autonomic nervous system in hyperglycemia due to 2-deoxy-D-glucose.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Glucose; Circadian Rhythm; Deoxyglucose; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperglycemia; Insulin; Male; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Hypoinsulinemic and hyperglycemic effects of beta-endorphin in rabbits.
Topics: Animals; Atropine; beta-Endorphin; Blood Glucose; Endorphins; Female; Glucagon; Hyperglycemia; Injections, Intravenous; Insulin; Naloxone; Phentolamine; Propranolol; Quaternary Ammonium Compounds; Rabbits; Yohimbine | 1986 |
Hyperglycemia and obesity as determinants of glucose, insulin, and glucagon responses to beta-endorphin in human diabetes mellitus.
Topics: Adult; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endorphins; Glucagon; Humans; Hyperglycemia; Infusions, Intravenous; Middle Aged; Obesity | 1987 |
Modulation of plasma glucose levels by thyrotropin-releasing hormone administered intracerebroventricularly in the rat.
Topics: Adrenalectomy; Animals; Blood Glucose; Glucagon; Hyperglycemia; Hyperinsulinism; Injections, Intraventricular; Insulin; Male; Rats; Rats, Inbred Strains; Streptozocin; Thyrotropin-Releasing Hormone; Vagotomy; Vagus Nerve | 1988 |
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Ketone Bodies; Male; Norepinephrine; Propranolol; Receptors, Adrenergic, beta | 1985 |
Hyperglycemia after intense exercise in IDDM subjects during continuous subcutaneous insulin infusion.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydroxybutyrates; Hyperglycemia; Insulin; Insulin Infusion Systems; Lactates; Male; Physical Exertion; Pyruvates; Reference Values | 1988 |
Changes in plasma glucagon, pancreatic polypeptide and insulin during development of alloxan diabetes mellitus in dog.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Glucagon; Hyperglycemia; Immunohistochemistry; Injections, Intravenous; Insulin; Pancreatic Polypeptide | 1988 |
The abnormal responses of A and B cells in pancreatic monolayer cultures of neonatal rats born to hyperglycemic mothers.
Topics: Animals; Animals, Newborn; Cells, Cultured; Female; Glucagon; Glucose; Homeostasis; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pregnancy; Rats; Rats, Inbred Strains | 1988 |
Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Glipizide; Glucagon; Glucose; Glyburide; Humans; Hyperglycemia; Insulin; Insulin Secretion; Kinetics; Liver; Sulfonylurea Compounds | 1987 |
Thyrotropin-releasing hormone (TRH) blocks glucagon-induced hyperglycemia in mice: dissociation of the antihyperglycemic and pituitary actions of TRH.
Topics: Animals; Blood Glucose; Glucagon; Hyperglycemia; Hypophysectomy; Male; Mice; Mice, Inbred ICR; Pituitary Gland; Reference Values; Thyrotropin-Releasing Hormone | 1988 |
The roles of glucagon and adrenal epinephrine in mediating hyperglycemia induced by third cerebroventricular injection of bombesin.
Topics: Animals; Bombesin; Epinephrine; Glucagon; Hyperglycemia; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains | 1988 |
Postexercise dose-response relationship between plasma glucose and insulin secretion.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Blood Pressure; C-Peptide; Calorimetry; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Growth Substances; Heart Rate; Humans; Hydrocortisone; Hydroxybutyrates; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Male; Norepinephrine; Physical Exertion; Proinsulin | 1988 |
Hormonal control of substrate cycling in humans.
Topics: Adult; Blood Glucose; Epinephrine; Fatty Acids; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Prednisone; Triglycerides | 1988 |
Pancreastatin inhibits insulin secretion and stimulates glucagon secretion in mice.
Topics: Animals; Blood Glucose; Carbachol; Chromogranin A; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Mice; Pancreatic Hormones; Phentolamine; Propranolol | 1988 |
Evolution of abnormal insulin secretory responses during 48-h in vivo hyperglycemia.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Osmolar Concentration; Perfusion; Time Factors | 1988 |
Failure of nocturnal hypoglycemia to cause fasting hyperglycemia in patients with insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fasting; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Hypoglycemia; Insulin; Male; Norepinephrine; Time | 1987 |
Hormonal responses during development of streptozotocin diabetes in rats.
Topics: Animals; Corticosterone; Diabetes Mellitus, Experimental; Glucagon; Glucose Tolerance Test; Growth; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1987 |
Effect of the enteroinsular axis on both the A- and B-cell response to arginine after oral glucose in man.
Topics: Administration, Oral; Adult; Arginine; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged | 1987 |
Inhibition of gastric acid secretion in humans by glucagon during euglycemia, hyperglycemia, and hypoglycemia.
Topics: Adult; Blood Glucose; Female; Gastric Acid; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Male; Pentagastrin; Stimulation, Chemical | 1988 |
Antecedent chronic hyperglycaemia blocks phlorizin-induced insulin resistance in the dog.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glycosuria; Hyperglycemia; Insulin Resistance; Kidney; Male; Phlorhizin | 1988 |
Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Islets of Langerhans; Male; Rats; Secretory Rate | 1986 |
Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues.
Topics: C-Peptide; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Insulin; Liver; Male; Middle Aged; Tritium | 1986 |
Effects of hyperglycemia on glucose production and utilization in humans. Measurement with [23H]-, [33H]-, and [614C]glucose.
Topics: Adult; Blood Glucose; C-Peptide; Carbon Radioisotopes; Female; Glucagon; Glucose; Glucose-6-Phosphate; Glucosephosphates; Growth Hormone; Humans; Hyperglycemia; Insulin; Liver Glycogen; Male; Middle Aged; Tritium | 1986 |
Hyperglucagonemia in L-asparaginase induced diabetes mellitus.
Topics: Alanine; Asparaginase; Child; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Insulin; Leukemia, Lymphoid | 1986 |
Hypoglycemia and hyperglycemia in tiny infants.
Topics: Blood Glucose; Brain; Female; Follow-Up Studies; Glucagon; Humans; Hyperglycemia; Hypoglycemia; Infant, Newborn; Infant, Premature, Diseases; Insulin; Liver; Maternal-Fetal Exchange; Pregnancy | 1986 |
Selective unresponsiveness of pancreatic beta-cells to acute sulfonylurea stimulation during sulfonylurea therapy in NIDDM.
Topics: Aged; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Islets of Langerhans; Male; Middle Aged; Rats; Sulfonylurea Compounds; Tolazamide; Tolbutamide | 1986 |
Hormonal responses associated with early hyperglycemia after graded hemorrhage in dogs.
Topics: Animals; Blood Glucose; Dogs; Epinephrine; Female; Glucagon; Hemodynamics; Hemorrhage; Hydrocortisone; Hyperglycemia; Insulin; Kinetics; Male; Norepinephrine | 1986 |
Splanchnic neural regulation of insulin and glucagon secretion in the isolated perfused human pancreas.
Topics: Adolescent; Adult; Aged; Electric Stimulation; Female; Glucagon; Glucose; Humans; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Male; Middle Aged; Pancreas; Phentolamine; Splanchnic Nerves | 1987 |
Exercise and the management of diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Glucagon; Glucose; Humans; Hyperglycemia; Hypoglycemia; Ketone Bodies; Physical Exertion | 1987 |
Alterations of insulin and glucose metabolism during cardiopulmonary bypass under normothermia.
Topics: Blood Glucose; Body Temperature; Cardiopulmonary Bypass; Female; Glucagon; Humans; Hyperglycemia; Insulin; Intraoperative Period; Lipid Metabolism; Male; Middle Aged; Time Factors | 1985 |
alpha-Glucosidase inhibition improves postprandial hyperglycemia and decreases insulin requirements in insulin-dependent diabetes mellitus.
Topics: Absorption; Acarbose; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Food; Glucagon; Glucose; Glucosidases; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Insulin; Insulin Infusion Systems; Male; Oligosaccharides; Trisaccharides; Xylose | 1985 |
Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Hyperglycemia; Islets of Langerhans; Phlorhizin | 1985 |
Hyper-G stress-induced hyperglycemia in rats mediated by glucoregulatory hormones.
Topics: Aerospace Medicine; Animals; Blood Glucose; Glucagon; Gravitation; Hyperglycemia; Insulin; Lactates; Liver Glycogen; Male; Muscles; Rats; Rats, Inbred Strains | 1985 |
Effects of gestational hyperglycemia on glucose metabolism and its hormonal control in the fasted, newborn rat during the early postnatal period.
Topics: Age Factors; Animals; Animals, Newborn; Catecholamines; Fasting; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Liver Glycogen; Pregnancy; Rats | 1985 |
Diminished glucagon response to epinephrine in physically trained diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Hyperglycemia; Insulin; Male; Physical Endurance; Rats; Rats, Inbred Strains | 1985 |
Effects of gastric inhibitory polypeptide in the response to prolonged parenteral or enteral alimentation in rats.
Topics: Animals; Blood Glucose; Body Weight; Dogs; Enteral Nutrition; Gastric Inhibitory Polypeptide; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Parenteral Nutrition, Total; Radioimmunoassay; Rats; Rats, Inbred Strains | 1985 |
Hyperglycemic effect of high doses of dobutamine in the rat: studies of insulin and glucagon secretion.
Topics: Animals; Blood Glucose; Dobutamine; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Male; Mannitol; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Time course of changes in gluconeogenesis from various precursors in chronically endotoxemic rats.
Topics: Animals; Endotoxins; Glucagon; Gluconeogenesis; Hyperglycemia; Hypoglycemia; Lactates; Liver; Liver Glycogen; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sugar Phosphates; Time Factors | 1985 |
Letter: Hyperglucagonaemia after drugs.
Topics: Burns; Glucagon; Humans; Hyperglycemia | 1974 |
Studies of the action of neutral red on glycemia and on insulin and glucagon secretion in the dog.
Topics: Adrenalectomy; Animals; Blood Glucose; Blood Pressure; Dogs; Epinephrine; Glucagon; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Norepinephrine; Phenazines; Radioimmunoassay; Spectrometry, Fluorescence; Staining and Labeling; Time Factors | 1974 |
Function of the alpha cell in diabetic ketoacidosis.
Topics: Animals; Diabetic Ketoacidosis; Glucagon; Hyperglycemia; Insulin; Pancreas | 1973 |
[The diabetic disease (M.D.). Clinical picture and complications].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Coma; Diabetic Ketoacidosis; Diabetic Nephropathies; Diabetic Retinopathy; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Antibodies; Ketone Bodies; Radioimmunoassay; Tolbutamide | 1974 |
A combined biochemical and histological study on the islets of Langerhans in the genetically obese hyperglycaemic mouse and the lean mouse, including observations on the effects of streptozotocin treatment.
Topics: Animals; Blood Glucose; Body Weight; Cell Count; Glucagon; Histocytochemistry; Hyperglycemia; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Obesity; Organ Size; Pancreas; Streptozocin | 1973 |
[Metabolism in mongoloid children. Studies using heart catheterization].
Topics: Adolescent; Blood Glucose; Carbohydrate Metabolism; Cardiac Catheterization; Child; Child, Preschool; Down Syndrome; Epinephrine; Female; Glucagon; Humans; Hyperglycemia; Lactates; Lipid Metabolism; Male; Methods; Thiamine Deficiency | 1972 |
The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Cholecystokinin; Dogs; Epinephrine; Gastrins; Glucagon; Growth Hormone; Hyperglycemia; Insulin; Secretin; Vasopressins | 1967 |
Conditioned glycemic responses in the control of food intake.
Topics: Animals; Blood Glucose; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Extinction, Psychological; Female; Glucagon; Hunger; Hyperglycemia; Hypoglycemia; Injections, Intraperitoneal; Insulin; Isotonic Solutions; Rats; Reinforcement, Psychology; Self Stimulation; Synaptic Transmission; Time Factors | 1968 |
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Tolbutamide; Trichlormethiazide | 1968 |
[Insulinoma in aged patients].
Topics: Adenoma, Islet Cell; Age Factors; Aged; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypertension; Pancreatic Neoplasms; Tolbutamide | 1968 |
Insulin and growth hormone regulation in organic hyperinsulinism.
Topics: Adenoma, Islet Cell; Adolescent; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Male; Pancreatic Neoplasms; Tolbutamide | 1971 |
Regulation of pancreatic beta-cell glycogen through cyclic-3,5-AMP.
Topics: Adenine Nucleotides; Animals; Cyclic AMP; Epinephrine; Female; Glucagon; Glucose; Glycogen; Hyperglycemia; In Vitro Techniques; Islets of Langerhans; Mice; Obesity; Theophylline | 1971 |
[Diagnosis of somatotropic insufficiency. Efficiency and tolerance of the beta 1-24-corticotrophin test].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arginine; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Hypoglycemia; Hypopituitarism; Injections, Intravenous; Male; Middle Aged; Pituitary Function Tests; Pyrogens | 1971 |
Normal carbohydrate metabolism and carbohydrate metabolism in trauma.
Topics: Adenosine Triphosphate; Anaerobiosis; Brain; Carbohydrate Metabolism; Cyclic AMP; Dietary Carbohydrates; Epinephrine; Glucagon; Gluconeogenesis; Glucose; Glycogen; Glycogen Synthase; Humans; Hyperglycemia; Hypoxia; Insulin; Ketone Bodies; Lactates; Liver; Muscles; Oxidative Phosphorylation; Physical Exertion; Postoperative Complications; Pyruvates; Starvation; Wounds and Injuries | 1974 |
The preparation of, and studies on, free cell suspensions from mouse pancreatic islets.
Topics: Animals; Cell Count; Cell Separation; Cell Survival; Culture Media; Cytological Techniques; Cytoplasmic Granules; DNA; Female; Glucagon; Glucose; Hyaluronoglucosaminidase; Hyperglycemia; Insulin; Insulin Secretion; Iodine Radioisotopes; Islets of Langerhans; Mice; Mice, Inbred Strains; Microbial Collagenase; Microscopy, Electron; Obesity; Pronase; Theophylline | 1974 |
[Investigation of sugar metabolism by non-isotope methods].
Topics: Adrenocorticotropic Hormone; beta-Lipotropin; Blood Glucose; Duodenum; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth Hormone; Humans; Hydrocortisone; Hyperglycemia; Insulin; Intestinal Absorption; Liver; Mathematics; Stomach; Tolbutamide | 1973 |
Presence and mobilization of glycogen in mammalian pancreatic beta cells.
Topics: Animals; Cyclic AMP; Fluorometry; Glucagon; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glycogen; Hexokinase; Hyperglycemia; Ischemia; Islets of Langerhans; Mice; NADP; Obesity; Phosphoglucomutase | 1969 |
Effects of hyperglycemia, tolbutamide and glucagon on the pathways of glucose oxidation in the goosefish islet in vitro.
Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Fishes; Glucagon; Glucose; Hyperglycemia; Islets of Langerhans; NAD; NADP; Nucleotides; Oxygen; Pyridines; Tolbutamide | 1970 |
Carbohydrate metabolism in pregnancy. XI. Response of plasma glucagon to overnight fast and oral glucose during normal pregnancy and in gestational diabetes.
Topics: Administration, Oral; Carbohydrate Metabolism; Drug Hypersensitivity; Fasting; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Parity; Postpartum Period; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, Third; Time Factors | 1974 |
Paradoxical glucagon release in obese hyperglycemic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucagon; Hyperglycemia; Mice; Mice, Inbred Strains; Mutation; Obesity; Pancreas; Perfusion; Time | 1974 |
Serum glucagon and insulin levels and their relationship to blood glucose values in patients with acute myocardial infarction and acute coronary insufficiency.
Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis; Blood Glucose; Coronary Disease; Creatine Kinase; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Myocardial Infarction; Radioimmunoassay; Shock, Cardiogenic | 1974 |
Suppressive effect of secretin upon pancreatic alpha cell function.
Topics: Animals; Depression, Chemical; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Hydrochloric Acid; Hyperglycemia; Insulin; Islets of Langerhans; Male; Secretin | 1972 |
Insulin-glucagon ratio.
Topics: Alanine; Animals; Blood Glucose; Diet; Dietary Carbohydrates; Dietary Proteins; Dogs; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Islets of Langerhans; Liver | 1972 |
[Glucagon in the treatment of acute pancreatitis. A new therapeutic principle?].
Topics: Acute Disease; Animals; Dogs; Duodenum; Gastric Juice; Glucagon; Humans; Hyperglycemia; Pancreas; Pancreatitis; Secretin | 1972 |
Effect of 2-deoxyglucose on insulin secretion in the rabbit.
Topics: Animals; Catheterization; Ergotamine; Female; Glucagon; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Portal Vein; Rabbits; Time Factors; Tolbutamide | 1973 |
The effect of insulin on the alpha-cell response to hyperglycemia in long-standing alloxan diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Hyperglycemia; Insulin; Islets of Langerhans; Time Factors | 1974 |
Diabetes in the sand-rat: diabetogenesis, responses to mannoheptulose and atriplex ash.
Topics: Animals; Basal Metabolism; Blood Glucose; Cataract; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diet; Disaccharides; Glucagon; Glucose Tolerance Test; Glycosuria; Heptoses; Hyperglycemia; Mannose; Obesity; Plants, Medicinal; Rats; Respiration; Species Specificity | 1972 |
[Studies on insulinemia in Graves-Basedow disease].
Topics: Adolescent; Adult; Glucagon; Glucose Tolerance Test; Graves Disease; Humans; Hyperglycemia; Hyperthyroidism; Insulin; Intestinal Absorption; Middle Aged; Prediabetic State; Radioimmunoassay | 1972 |
Hyperglycemic and glycogenolytic effects of vasoactive intestinal polypeptide.
Topics: Animals; Dogs; Glucagon; Glycogen; Hyperglycemia; In Vitro Techniques; Intestine, Small; Liver; Peptides; Rabbits; Vasodilator Agents | 1973 |
A case of transient hypoglycemia and hyperglycemia in a full-term neonate. A case study suggesting CNS causation.
Topics: 17-Ketosteroids; Central Nervous System Diseases; Chromatography; Creatinine; Electroencephalography; Female; Glucagon; Glucose; Glucose Tolerance Test; Glycosuria; Humans; Hyperglycemia; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Respiratory Insufficiency; Seizures | 1973 |
Evidence for a role of endogenous insulin and glucagon in the regulation of potassium homeostasis.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Homeostasis; Hyperglycemia; Hyperkalemia; Hypoglycemia; Infusions, Parenteral; Insulin; Insulin Secretion; Insulin, Long-Acting; Potassium; Potassium Chloride; Spectrophotometry, Atomic | 1973 |
Hyperglycemic and insulogenic effects of intravenous glucagon at different blood glucose levels.
Topics: Animals; Antibodies; Blood Glucose; Dogs; Fasting; Glucagon; Glucose; Hyperglycemia; Infusions, Parenteral; Injections, Intravenous; Insulin; Insulin Secretion; Stimulation, Chemical; Time Factors | 1973 |
Plasma levels of growth hormone and glucagon in diabetic patients and relatives of diabetic patients.
Topics: Adult; Arginine; Blood Glucose; Cortisone; Diabetes Mellitus; Diabetic Retinopathy; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Male; Middle Aged; Prediabetic State | 1973 |
Glucagon structure and function. II. Increased activity of iodoglucagon.
Topics: Adenylyl Cyclases; Animals; Blood Glucose; Cell Membrane; Cortisone; Enzyme Activation; Glucagon; Hyperglycemia; Iodine; Iodine Radioisotopes; Kinetics; Liver; Phosphorus Radioisotopes; Rabbits; Rats | 1973 |
Stimulation of glucagon secretion by epinephrine in man.
Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Humans; Hyperglycemia; Insulin; Male; Receptors, Adrenergic; Time Factors | 1973 |
Hypothalamic control of blood glucose level.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Blood Glucose; Catecholamines; Glucagon; Gluconeogenesis; Hyperglycemia; Hypothalamus; Insulin; Insulin Secretion; Liver; Liver Glycogen; Rabbits; Rats | 1973 |
Insulin response to glucagon in diabetic children.
Topics: Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fasting; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Insulin; Insulin Secretion; Prospective Studies; Time Factors | 1973 |
[The role of glucagon in child's body].
Topics: Adolescent; Age Factors; Blood Glucose; Child; Child, Preschool; Glucagon; Humans; Hyperglycemia; Infant; Time Factors | 1973 |
Hyperglucagonemia following thermal injury: insulin and glucagon in the posttraumatic catabolic state.
Topics: Adolescent; Adult; Burns; Child; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Wounds and Injuries | 1973 |
[Hypoglycemia].
Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Leucine; Liver Glycogen; Pancreatic Neoplasms; Thyroid Hormones; Tolbutamide | 1973 |
Effects of glucagon on plasma lipids in different types of primary hyperlipoproteinemia.
Topics: Adolescent; Adult; Blood Glucose; Body Weight; Cholesterol; Diet; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hyperglycemia; Hyperlipidemias; Injections, Intramuscular; Lipid Metabolism; Lipids; Male; Middle Aged; Time Factors; Triglycerides | 1974 |
Diminished response to glucagon in the dextros-primed neonate.
Topics: Blood Glucose; Child; Child, Preschool; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intravenous; Insulin; Time Factors | 1974 |
Abnormal secretion of insulin and glucagon by the in vitro perfused pancreas of the genetically diabetic Chinese hamster.
Topics: Animals; Blood Glucose; Cattle; Cricetinae; Diabetes Mellitus; Disease Models, Animal; Drug Combinations; Female; Glucagon; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Rats; Swine; Theophylline | 1974 |
Glucagon mediation of growth hormone secretion in juvenile diabetes mellitus.
Topics: Adolescent; Blood Glucose; Body Weight; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Growth Hormone; Humans; Hyperglycemia; Injections, Intravenous; Male; Methods; Propranolol; Stimulation, Chemical; Time Factors | 1974 |
Effects of prolonged glucagon administration to turtles (Chrysemys d'Orbignyi).
Topics: Adipose Tissue; Animals; Blood Glucose; Glucagon; Glycogen; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Liver Glycogen; Manometry; Muscles; Seasons; Turtles | 1967 |
Neutral red induced hyperglucagonemia.
Topics: Animals; Blood Glucose; Chromatography, Ion Exchange; Coloring Agents; Dogs; Glucagon; Hyperglycemia; Insulin; Islets of Langerhans; Liver Glycogen; Pancreas; Phenazines; Radioimmunoassay | 1968 |
Stimulation of glucagon secretion by tetragastrin.
Topics: Amides; Animals; Dogs; Gastrins; Glucagon; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Peptides; Propylene Glycols; Receptors, Drug; Stimulation, Chemical; Veins | 1970 |
Glucose production and utilization in the newborn puppy.
Topics: Age Factors; Animals; Animals, Newborn; Blood Glucose; Dogs; Female; Glucagon; Glucose; Guinea Pigs; Humans; Hyperglycemia; Hypoglycemia; Infant, Newborn; Insulin; Liver; Liver Glycogen; Pregnancy; Rabbits; Radioisotope Dilution Technique | 1970 |
Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Dietary Proteins; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Islets of Langerhans; Male | 1970 |
Pathogenetic aspects of the obese-hyperglycemic syndrome in mice (genotype obob). I. Function of the pancreatic B-cells.
Topics: Age Factors; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Obesity | 1970 |
Impairment of glucose homeostasis after hepatic ischemia.
Topics: Animals; Blood Pressure; Dogs; Glucagon; Glucose; Glucose Tolerance Test; Hyperglycemia; Hypoglycemia; Insulin; Insulin Secretion; Ischemia; Liver; Liver Circulation; Liver Transplantation | 1971 |
The effect of experimental insulin deficiency on glucagon secretion.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diazoxide; Dogs; Glucagon; Heptoses; Hexoses; Hyperglycemia; Insulin; Insulin Antibodies; Islets of Langerhans; Rats | 1971 |
Effect of hypothalamic stimulation on plasma glucose, insulin, and glucagon levels.
Topics: Adrenalectomy; Animals; Blood Glucose; Carbon Isotopes; Cerebral Cortex; Electric Stimulation; Epinephrine; Female; Glucagon; Homeostasis; Hyperglycemia; Hypothalamus; Immune Sera; Insulin; Islets of Langerhans; Liver; Radioimmunoassay; Rats; Sympathetic Nervous System | 1971 |
Studies of pancreatic alpha cell function in normal and diabetic subjects.
Topics: Adolescent; Adult; Arginine; Body Weight; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Diabetic Nephropathies; Fasting; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Middle Aged; Pancreas; Radioimmunoassay | 1970 |
[Differential action of temperature on hyperglycemic activity of glucagon and epinephrine: study in rats in deep hypothermia].
Topics: Animals; Blood Glucose; Epinephrine; Glucagon; Hyperglycemia; Hypothermia, Induced; Liver Glycogen; Male; Methoxamine; Rats | 1970 |
[Effect of glucagon-zinc on blood sugar and glycogen content of the rat fetal liver at the end of gestation].
Topics: Animals; Blood Glucose; Female; Fetus; Glucagon; Hyperglycemia; Liver; Liver Glycogen; Pregnancy; Rats; Time Factors | 1970 |
The ultrastructural aspect of A-cells of non-ketotic and ketotic diabetic animals: indications for stimulation and inhibition of glucagon production.
Topics: Animals; Cricetinae; Diabetes Mellitus; Diabetic Ketoacidosis; Glucagon; Hyperglycemia; Islets of Langerhans; Mice; Microscopy, Electron; Rats | 1970 |
Relationship between insulin and gut glucagon-like immunoreactivity (GLI) secretion in normal and gastrectomized subjects.
Topics: Adolescent; Adult; Allergy and Immunology; Female; Gastrectomy; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Immune Sera; Insulin; Male; Middle Aged; Radioimmunoassay | 1972 |
[Hyperglycemia and insulin resistance during glucagon infusion].
Topics: Aged; Female; Glucagon; Humans; Hyperglycemia; Injections, Intravenous; Insulin Resistance | 1972 |
Plasma insulin, glucagon, and nonesterified fatty acids in dogs with diabetes mellitus.
Topics: Acidosis; Age Factors; Animals; Antigens; Cattle; Diabetes Complications; Diabetes Mellitus; Dog Diseases; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Guinea Pigs; Hyperglycemia; Hyperlipidemias; Insulin; Insulin Antibodies; Insulin Secretion; Male; Pancreas; Pancreatic Diseases; Radioimmunoassay | 1972 |
Isolation from porcine-intestinal wall of a vasoactive octacosapeptide related to secretin and to glucagon.
Topics: Amino Acids; Animals; Cats; Chromatography, Gel; Chromatography, Ion Exchange; Countercurrent Distribution; Electrophoresis, Disc; Glucagon; Hydrolysis; Hyperglycemia; Intestine, Small; Mercaptoethanol; Methylcellulose; Muscle, Smooth; Pancreas; Peptides; Secretin; Swine; Vasodilator Agents | 1972 |
Hormones and crayfish blood sugar.
Topics: Animals; Blood Glucose; Crustacea; Epinephrine; Glucagon; Hyperglycemia; Insulin; Invertebrate Hormones; Stimulation, Chemical | 1971 |
Effects of glucagon on the splanchnic and the systemic circulation.
Topics: Animals; Blood Circulation; Blood Glucose; Blood Pressure; Carbon Dioxide; Cardiac Output; Celiac Artery; Central Venous Pressure; Dogs; Female; Glucagon; Heart Rate; Hepatic Artery; Hydrogen-Ion Concentration; Hyperglycemia; Liver Circulation; Male; Mesenteric Arteries; Oxygen; Potassium; Vascular Resistance | 1971 |
Effect of ecdysterone on hyperglycemia in experimental animals.
Topics: Alloxan; Animals; Carbon Isotopes; Cholestanes; Diabetes Mellitus, Experimental; Drug Antagonism; Glucagon; Glucose; Hyperglycemia; Insulin Antibodies; Invertebrate Hormones; Liver Glycogen; Male; Mice; Plant Growth Regulators; Protein Biosynthesis; Rats | 1971 |
[Glucagon-induced hyperglycemia as a measure of liver function].
Topics: Adolescent; Adult; Aged; Blood Glucose; Female; Galactose; Glucagon; Half-Life; Humans; Hyperglycemia; Injections, Intravenous; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Serum Albumin | 1971 |
[Effect of glucagon on extracellular potassium concentration measurements in aorta, hepatic vein and coronary sinus in man].
Topics: Aorta; Blood Glucose; Coronary Vessels; Extracellular Space; Glucagon; Hepatic Veins; Humans; Hyperglycemia; Hyperkalemia; Hypokalemia; Potassium; Time Factors; Veins | 1971 |
Comparison of some metabolic responses in normal and asthmatic subjects to epinephrine and glucagon.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Hyperglycemia; Male; Sympathomimetics | 1967 |
Effect of high spinal cord section on epinephrine hyperglycemia.
Topics: Animals; Blood Glucose; Brain; Cordotomy; Dogs; Epinephrine; Glucagon; Gluconeogenesis; Hyperglycemia; Hypothalamus; Infusions, Parenteral; Lactates; Liver Glycogen; Spinal Cord; Sympathetic Nervous System; Time Factors | 1968 |
THe glucagon plus galactose tolerance test. A preliminary report.
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Galactose; Glucagon; Glucose Tolerance Test; Glycogen Storage Disease; Humans; Hyperglycemia; Liver; Liver Diseases; Middle Aged | 1970 |
Enhanced postglucose hypophosphatemia during starvation therapy of obesity.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Body Weight; Depression, Chemical; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Insulin; Liver; Middle Aged; Muscles; Obesity; Phosphorus; Stimulation, Chemical; Time Factors; Tolbutamide | 1969 |
Fatty acid, epinephrine, and glucagon hyperglycemia in normal and depancreatized sheep.
Topics: Animals; Blood Glucose; Butyrates; Epinephrine; Fatty Acids; Glucagon; Glycogen; Hyperglycemia; Liver; Pancreas; Sheep | 1969 |
Zinc glucagon depression of blood amino acids in rabbits.
Topics: Amino Acids; Animals; Blood Glucose; Depression, Chemical; Glucagon; Gluconeogenesis; Hyperglycemia; Rabbits; Zinc | 1969 |
Hepatic glycogen and blood glucose control.
Topics: Animals; Blood Glucose; Diet; Drug Synergism; Epinephrine; Ergotamine; Fasting; Glucagon; Hyperglycemia; Hypoglycemia; Insulin; Liver; Liver Glycogen; Male; Propranolol; Rabbits; Rats; Time Factors | 1969 |
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Glucagon; Glycosuria; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Mice; Mice, Inbred Strains; Obesity; Pancreas; Tolbutamide | 1969 |
Hyperglycemic response to massive doses of commercial insulin.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Insulin; Insulin Resistance; Male; Rabbits | 1970 |
Effect of enteric hormones on insulin secretion.
Topics: Adult; Blood Glucose; Cholecystokinin; Diabetes Mellitus; Female; Glucagon; Hormones; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Prediabetic State; Secretin; Tolbutamide | 1970 |
[Influence of glucagon on mesenteric blood flow in different blood sugar concentrations].
Topics: Animals; Blood Flow Velocity; Blood Glucose; Dogs; Glucagon; Hyperglycemia; Mesentery | 1970 |
[Glucose regulation].
Topics: Animals; Blood Glucose; Catecholamines; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Food; Glucagon; Glucose; Glucose Tolerance Test; Glycosuria; Growth Hormone; Hyperglycemia; Insulin; Intestinal Absorption; Liver; Liver Glycogen; Male; Rats; Starvation | 1970 |
Stimulation of glucagon secretion by arginine and histidine infused intrapancreatically.
Topics: Animals; Arginine; Arteries; Dogs; Femoral Artery; Glucagon; Histidine; Hyperglycemia; Infusions, Parenteral; Insulin; Pancreas; Stimulation, Chemical; Veins | 1971 |
[Glycemic reactions following hypothiazide].
Topics: Animals; Chlorothiazide; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Male; Pancreas; Purines; Rats; Sympathetic Nervous System | 1967 |
[On the mechanism of action of phenethylbiguanide (PEBG). 3. Effects on glucagon-induced hyperglycemia in vivo].
Topics: Animals; Biguanides; Glucagon; Hyperglycemia; Hypoglycemic Agents; Rabbits | 1967 |
[Total pancreatectomy in the goose].
Topics: Animals; Blood Glucose; Fasting; Female; Geese; Glucagon; Glucose; Glucose Tolerance Test; Hyperglycemia; Hypoglycemia; Male; Pancreatectomy | 1967 |
Characterization of the responses of circulating glucagon-like immunoreactivity to intraduodenal and intravenous administration of glucose.
Topics: Animals; Blood Glucose; Chromatography; Dogs; Glucagon; Glucose; Hyperglycemia; Immunoassay; Insulin; Insulin Secretion; Intestinal Absorption; Intestines; Iodine Radioisotopes; Jejunum; Pancreas; Perfusion | 1968 |
Glucagon and fetal growth in the rat.
Topics: Animals; Appetite; Blood Glucose; Body Weight; Embryonic and Fetal Development; Female; Fetus; Glucagon; Hyperglycemia; Injections, Subcutaneous; Liver; Liver Glycogen; Placenta; Pregnancy; Rats | 1968 |
Characterization of response of circulating glucagon to intraduodenal and intravenous administration of amino acids.
Topics: Amino Acids; Animals; Blood Glucose; Cholecystokinin; Dogs; Duodenum; Glucagon; Hyperglycemia; Injections, Intravenous; Insulin; Male; Pancreas; Radioimmunoassay | 1968 |
Comparative hypocalcemic and hypophosphatemic effects of glucagon and thyrocalcitonin.
Topics: Animals; Blood Glucose; Calcitonin; Calcium; Glucagon; Hyperglycemia; Hypocalcemia; Phosphorus; Phosphorus Metabolism Disorders; Rats | 1968 |
The mode of action of glymidine (Gondafon) with some speculations about the molecular and intracellular action of insulinotrophic drugs.
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Leucine; Pancreas; Stimulation, Chemical; Sulfonamides | 1968 |
[On the mathematical analysis of hyperglycemia caused by glucagon evaluated as a liver function in the aged].
Topics: Aged; Glucagon; Humans; Hyperglycemia; Liver Diseases; Liver Function Tests | 1968 |
Effect of blood glucose on glucagon secretion in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Glucose; Dogs; Glucagon; Hemostasis; Hyperglycemia; Hypoglycemia; Insulin; Pancreas; Pancreatectomy; Radioimmunoassay; Tolbutamide; Veins | 1969 |
Control of pancreatic glucagon secretion by glucose.
Topics: Amino Acids; Animals; Blood Glucose; Dogs; Duodenum; Glucagon; Glucose; Homeostasis; Hyperglycemia; Hypoglycemia; Infusions, Parenteral; Insulin; Pancreas; Radioimmunoassay; Veins | 1969 |
The role of aminogenic glucagon secretion in blood glucose homeostasis.
Topics: Amino Acids; Animals; Blood Glucose; Catheterization; Cholecystokinin; Dogs; Glucagon; Homeostasis; Hyperglycemia; Lipids; Pancreas | 1969 |
[The role of glucagon in glucide metabolism].
Topics: Carbohydrate Metabolism; Chromaffin System; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Antagonists | 1969 |
The effect of epinephrine on immunoreactive insulin levels in man.
Topics: Adult; Blood; Epinephrine; Glucagon; Glucose; Humans; Hyperglycemia; Insulin; Male; Tolbutamide | 1966 |
Action of neutral red on the secretion of glucagon and glucose metabolism in the rat.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Glucose; Coloring Agents; Cortisone; Fasting; Female; Glucagon; Hyperglycemia; Male; Pancreatectomy; Rats | 1966 |
Effect of glucagon on the metabolism of lipids and on urea formation by the perfused rat liver.
Topics: Animals; Blood Glucose; Cholesterol; Fatty Acids; Glucagon; Hyperglycemia; Hyperlipidemias; Ketone Bodies; Lipid Metabolism; Liver; Perfusion; Rats; Urea | 1966 |
Hyperglycaemic effect of neurohypophysial hormones in the chicken, Gallus domesticus.
Topics: Animals; Blood Glucose; Glucagon; Hyperglycemia; In Vitro Techniques; Oxytocin; Pituitary Hormones, Posterior; Poultry; Vasotocin | 1966 |
Effect of glucagon on plasma free fatty acids of normal and pancreatectomized dogs.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids; Glucagon; Hyperglycemia; Insulin; Lipid Metabolism; Lipids; Pancreas; Pancreatectomy | 1966 |
Interrelationship of glucagon, insulin and glucose. The insulinogenic effect of glucagon.
Topics: Adult; Blood Glucose; Dietary Carbohydrates; Female; Glucagon; Humans; Hyperglycemia; Immunoassay; Injections, Intravenous; Insulin; Male; Middle Aged; Tolbutamide | 1966 |
Heterogeneity of glucagon-like immunoreactive peptides (GLi) in the intestine of obese hyperglycaemic (ob/ob) mice.
Topics: Animals; Chromatography, Gel; Glucagon-Like Peptides; Hyperglycemia; Intestines; Mice; Mice, Obese; Obesity; Peptides | 1983 |