pentamidine has been researched along with Hyperglycemia in 9 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiprotozoal agent pentamidine, used for the treatment of Pneumocystis jirovecii pneumonia (PCP), is known to cause abnormalities in blood glucose homeostasis, such as hypoglycemia and hyperglycemia." | 7.78 | Effect of cimetidine on pentamidine induced hyperglycemia in rats. ( Arino, T; Ishiwata, Y; Karakawa, S; Nagata, M; Yasuhara, M, 2012) |
| "Severe hemorrhagic pancreatitis developed in a patient with the acquired immunodeficiency syndrome (AIDS) during pentamidine isethionate treatment for Pneumocystis carinii pneumonia." | 7.67 | Pentamidine-associated fatal acute pancreatitis. ( el-Sadr, W; Rahal, JJ; Simberkoff, MS; Wolf, BZ; Zuger, A, 1986) |
| "The antiprotozoal agent pentamidine, used for the treatment of Pneumocystis jirovecii pneumonia (PCP), is known to cause abnormalities in blood glucose homeostasis, such as hypoglycemia and hyperglycemia." | 3.78 | Effect of cimetidine on pentamidine induced hyperglycemia in rats. ( Arino, T; Ishiwata, Y; Karakawa, S; Nagata, M; Yasuhara, M, 2012) |
| " Demographic information, family histories of diabetes mellitus, body weights, CD4+ lymphocyte counts, and use of corticosteroids, megestrol acetate, pentamidine, or didanosine were recorded for subjects meeting the case definition." | 3.70 | Severe hyperglycemia in an HIV clinic: preexisting versus drug-associated diabetes mellitus. ( Kilby, JM; Tabereaux, PB, 1998) |
| "Severe hemorrhagic pancreatitis developed in a patient with the acquired immunodeficiency syndrome (AIDS) during pentamidine isethionate treatment for Pneumocystis carinii pneumonia." | 3.67 | Pentamidine-associated fatal acute pancreatitis. ( el-Sadr, W; Rahal, JJ; Simberkoff, MS; Wolf, BZ; Zuger, A, 1986) |
| "Pentamidine was frequently associated with dysglycaemia due to its pancreatic beta-cell cytotoxic effects but is now used less often to treat Pneumocystis carinii pneumonia in immunosuppressed patients." | 2.39 | Drug-induced disorders of glucose metabolism. Mechanisms and management. ( Chan, JC; Cockram, CS; Critchley, JA, 1996) |
| "The pentamidine-treated dysglycemic patients differed from their euglycemic counterparts by higher pentamidine doses (P < 0." | 1.29 | Pentamidine-induced derangements of glucose homeostasis. Determinant roles of renal failure and drug accumulation. A study of 128 patients. ( Assan, D; Assan, R; Chotard, L; Matheron, S; Mayaud, C; Perronne, C; Zucman, D, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arino, T | 1 |
| Karakawa, S | 1 |
| Ishiwata, Y | 1 |
| Nagata, M | 1 |
| Yasuhara, M | 1 |
| Assan, R | 1 |
| Perronne, C | 1 |
| Assan, D | 1 |
| Chotard, L | 1 |
| Mayaud, C | 1 |
| Matheron, S | 1 |
| Zucman, D | 1 |
| Lu, CP | 1 |
| Wu, HP | 1 |
| Chuang, LM | 1 |
| Lin, BJ | 1 |
| Chuang, CY | 1 |
| Tai, TY | 1 |
| Chan, JC | 1 |
| Cockram, CS | 1 |
| Critchley, JA | 1 |
| Gambini, D | 1 |
| Brambilla, AM | 1 |
| Galli, C | 1 |
| Castagna, A | 1 |
| Veglia, F | 1 |
| Lazzarin, A | 1 |
| Kilby, JM | 1 |
| Tabereaux, PB | 1 |
| Shen, M | 1 |
| Orwoll, ES | 1 |
| Conte, JE | 1 |
| Prince, MJ | 1 |
| Singh, NK | 1 |
| Agrawal, SK | 1 |
| Jha, TK | 1 |
| Zuger, A | 1 |
| Wolf, BZ | 1 |
| el-Sadr, W | 1 |
| Simberkoff, MS | 1 |
| Rahal, JJ | 1 |
1 review available for pentamidine and Hyperglycemia
| Article | Year |
|---|---|
Drug-induced disorders of glucose metabolism. Mechanisms and management.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converti | 1996 |
8 other studies available for pentamidine and Hyperglycemia
| Article | Year |
|---|---|
Effect of cimetidine on pentamidine induced hyperglycemia in rats.
Topics: Animals; Antiprotozoal Agents; Blood Glucose; Catecholamine Plasma Membrane Transport Proteins; Cime | 2012 |
Pentamidine-induced derangements of glucose homeostasis. Determinant roles of renal failure and drug accumulation. A study of 128 patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Diabetes Mellitus; Female; Humans; Hyperglycemia; Hypo | 1995 |
Pentamidine-induced hyperglycemia and ketosis in acquired immunodeficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Diabetic Ketoacidosis; Fatal Outcom | 1995 |
Increased hyperglycaemia during cotreatment with pentamidine and corticosteroids in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; | 1997 |
Severe hyperglycemia in an HIV clinic: preexisting versus drug-associated diabetes mellitus.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-HIV Agents; Diabetes Complications; Diabetes Mellitus; Di | 1998 |
Pentamidine-induced pancreatic beta-cell dysfunction.
Topics: Acquired Immunodeficiency Syndrome; Amidines; Chromatography, High Pressure Liquid; Diabetes Mellitu | 1989 |
Persistent hyperglycaemia requiring insulin therapy following the use of pentamidine in the treatment of kala-azar.
Topics: Adult; Child; Humans; Hyperglycemia; Insulin; Leishmaniasis; Male; Pentamidine | 1989 |
Pentamidine-associated fatal acute pancreatitis.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Amidines; Drug Hypersensitivity; Hemorrhag | 1986 |