Page last updated: 2024-11-08

triiodothyronine and Hyperglycemia

triiodothyronine has been researched along with Hyperglycemia in 29 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect."5.34Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007)
" Several major conclusions are justified from the data obtained: (1) Although the hepatic specific activity of fatty acid synthetase is higher in obese than in non obese animals pair-fed chow, no difference in hepatic activities is apparent in animals pair-fed the fat-free diet; (2) The higher enzymatic activity in obese animals fed chow is related to a higher content of enzyme, and this higher content is associated with a higher rate of enzyme synthesis; (3) The decrease in hepatic synthetase activity with starvation is distinctly more striking in non obese than in obese animals, and the changes in activity reflect changes in content of enzyme; (4) With starvation there is a decrease in synthesis of enzyme in obese and non obese animals, but only in non obese animals is there also a marked increase in the rate of synthetase degradation (t1/2 = 24 h during starvation, t1/2 = 76 h during normalfeeding); (5) Refeeding starved mice a fat-free diet results in a more striking increase in hepatic synthetase activity in non obese than in obese animals; (6) Administration of triiodothyronine causes a more marked increase in hepatic synthetase activity in non obese than in obese animals."3.65Regulation of hepatic fatty acid synthetase in the obese-hyperglycemic mutant mouse. ( Marasa, JC; Volpe, JJ, 1975)
"Critical illness is often associated with reduced TSH and thyroid hormone secretion as well as marked changes in peripheral thyroid hormone metabolism, resulting in low serum T(3) and high rT(3) levels."2.71Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. ( Kaptein, E; Peeters, RP; Van den Berghe, G; van Toor, H; Visser, TJ; Wouters, PJ, 2003)
"After treatment for myxedema with liothyronine 5 mcg two times per day and levothyroxine 175 mcg once daily via a nasogastric tube and diabetic ketoacidosis with intravenously administered fluid and insulin, his clinical condition rapidly improved including mental status, hyperglycemia, and acidosis."1.51Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report. ( Kim, EY; Kim, JJ, 2019)
"It seems that hyperglycemia is not an important risk factor for future diabetes."1.38Thyroid function and stress hormones in children with stress hyperglycemia. ( Bordbar, MR; Haghpanah, S; Karamizadeh, Z; Karimi, M; Omrani, GH; Taj-Aldini, R, 2012)
"Notably, diabetic nephropathy was accompanied by a significant decrease in PI3K activity and an increase in TGF-β1 expression in kidneys."1.37Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes. ( Lin, Y; Sun, Z, 2011)
"Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect."1.34Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's4 (13.79)18.2507
2000's5 (17.24)29.6817
2010's9 (31.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katz, LS1
Xu, S1
Ge, K1
Scott, DK1
Gershengorn, MC1
Kamrul-Hasan, M1
Siddiqui, NI1
Shubha, RA1
Abu-Bakar, M1
Chanda, PK1
Haque, FI1
Kim, JJ1
Kim, EY1
Finan, B1
Clemmensen, C1
Zhu, Z1
Stemmer, K1
Gauthier, K1
Müller, L1
De Angelis, M1
Moreth, K1
Neff, F1
Perez-Tilve, D1
Fischer, K1
Lutter, D1
Sánchez-Garrido, MA1
Liu, P1
Tuckermann, J1
Malehmir, M1
Healy, ME1
Weber, A1
Heikenwalder, M1
Jastroch, M1
Kleinert, M1
Jall, S1
Brandt, S1
Flamant, F1
Schramm, KW1
Biebermann, H1
Döring, Y1
Weber, C1
Habegger, KM1
Keuper, M1
Gelfanov, V1
Liu, F1
Köhrle, J1
Rozman, J1
Fuchs, H1
Gailus-Durner, V1
Hrabě de Angelis, M1
Hofmann, SM1
Yang, B1
Tschöp, MH1
DiMarchi, R1
Müller, TD1
Parmar, HS1
Kar, A2
Derde, S1
Vanhorebeek, I1
Ververs, EJ1
Vanhees, I1
Darras, VM1
Van Herck, E1
Larsson, L1
Van den Berghe, G2
Lin, Y2
Sun, Z2
Bordbar, MR1
Taj-Aldini, R1
Karamizadeh, Z1
Haghpanah, S1
Karimi, M1
Omrani, GH1
Matsen, ME1
Thaler, JP1
Wisse, BE1
Guyenet, SJ1
Meek, TH1
Ogimoto, K1
Cubelo, A1
Fischer, JD1
Kaiyala, KJ1
Schwartz, MW1
Morton, GJ1
Peeters, RP1
Wouters, PJ1
Kaptein, E1
van Toor, H1
Visser, TJ1
KELLEN, J1
Szkudelski, T1
Michalski, W1
Szkudelska, K1
Jatwa, R1
Bhatt, P1
Makwana, D1
Santani, D1
Goyal, R1
Alexander, CM1
Lum, SM1
Rhodes, J1
Boarman, C1
Nicoloff, JT1
Kumar, D1
Achmadi, J1
Terashima, Y1
Chapa, AM1
Fernandez, JM1
Thompson, DL1
Tempelman, RJ1
Berrio, LF1
Croom, WJ1
Hagler, WM1
Shimokawa, T1
Kato, M1
Shioduka, K1
Irie, J1
Ezaki, O1
Garthwaite, TL1
Kalkhoff, RK1
Guansing, AR1
Hagen, TC1
Menahan, LA1
Blichert-Toft, M1
Christensen, V1
Engquist, A1
Fog-Moller, F1
Kehlet, H1
Madsen, SN1
Skovsted, L1
Thode, J1
Olgaard, K1
Hall, R1
Gomez-Pan, A1
Volpe, JJ1
Marasa, JC1
Wronska, D1
Niezgoda, J1
Sechman, A1
Bobek, S1
Röjdmark, S1
Berg, A1
Ekström, U1
Ikeda, T1
Takeuchi, T1
Ito, Y1
Murakami, I1
Mokuda, O1
Tominaga, M1
Mashiba, H1
Mohamed, HF1
Ageel, AM1
el-Denshary, ES1
Abu-Jayyab, AR1
el-Wakkad, I1
Gharib, H1
Munoz, JM1
Vinik, A1
Pimstone, B1
Buchanan-Lee, B1

Reviews

1 review available for triiodothyronine and Hyperglycemia

ArticleYear
The hypothalamic regulatory hormones and their clinical applications.
    Advances in clinical chemistry, 1976, Volume: 18

    Topics: Female; Follicle Stimulating Hormone; Gastrins; Glucagon; Gonadotropin-Releasing Hormone; Humans; Hy

1976

Trials

1 trial available for triiodothyronine and Hyperglycemia

ArticleYear
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:7

    Topics: Aged; Aged, 80 and over; Biopsy; Critical Illness; Humans; Hyperglycemia; Hypoglycemic Agents; Insul

2003

Other Studies

27 other studies available for triiodothyronine and Hyperglycemia

ArticleYear
T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice.
    Endocrinology, 2018, 01-01, Volume: 159, Issue:1

    Topics: Active Transport, Cell Nucleus; Adipocytes, Brown; Adipogenesis; Animals; Basic Helix-Loop-Helix Leu

2018
Low Free T₃ was Associated with Poor Glycemic Control in Type 2 Diabetes in a Hospital Based Study in Bangladesh.
    Mymensingh medical journal : MMJ, 2018, Volume: 27, Issue:2

    Topics: Adult; Bangladesh; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia

2018
Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report.
    Journal of medical case reports, 2019, Mar-04, Volume: 13, Issue:1

    Topics: Adult; Blood Gas Analysis; Coma; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Glycated Hemoglob

2019
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
    Cell, 2016, Oct-20, Volume: 167, Issue:3

    Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes M

2016
Possible amelioration of atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia by the peel extracts of Mangifera indica, Cucumis melo and Citrullus vulgaris fruits in rats.
    BioFactors (Oxford, England), 2008, Volume: 33, Issue:1

    Topics: Animals; Ascorbic Acid; Atherosclerosis; Blood Glucose; Citrullus; Creatine Kinase, MB Form; Cucumis

2008
Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits.
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Actins; Animals; Blood Glucose; Body Weight; Critical Illness; Disease Models, Animal; Glucose; Hype

2010
Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes.
    British journal of pharmacology, 2011, Volume: 162, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Bloo

2011
Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes.
    The Journal of endocrinology, 2011, Volume: 209, Issue:2

    Topics: Albuminuria; Animals; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic

2011
Thyroid function and stress hormones in children with stress hyperglycemia.
    Endocrine, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Aging; Child; Child, Preschool; Cross-Sectional Studies; Female; Hormones; Human Growth

2012
In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.
    American journal of physiology. Endocrinology and metabolism, 2013, Apr-01, Volume: 304, Issue:7

    Topics: Acetates; Adipose Tissue, Brown; Adrenergic beta-3 Receptor Agonists; Animals; Body Composition; Dia

2013
[The "rebound phenomenon" in fat metabolism after triiodothyronine].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1960, Aug-15, Volume: 15

    Topics: Fats; Humans; Hyperglycemia; Lipid Metabolism; Triiodothyronine

1960
The effect of thyroid hormones on blood insulin level and metabolic parameters in diabetic rats.
    Journal of physiology and biochemistry, 2003, Volume: 59, Issue:2

    Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Energy Metabolism; Hyperglycemia;

2003
Cardio-protective role of terazosin is possibly mediated through alteration in thyroid function.
    European journal of pharmacology, 2006, Dec-03, Volume: 551, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Cholesterol, Dietary; Disease Models, Animal;

2006
Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body

2007
Rapid increase in both plasma fibronectin and serum triiodothyromine associated with treatment of diabetic ketoacidosis.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:2

    Topics: Adult; Diabetic Ketoacidosis; Female; Fibronectins; Humans; Hyperglycemia; Insulin; Kinetics; Male;

1983
The effect of propylthiouracyl-induced low thyroid function on secretion response and action of insulin in sheep.
    Domestic animal endocrinology, 1995, Volume: 12, Issue:2

    Topics: Animals; Blood Glucose; Female; Glucose; Glucose Clamp Technique; Hyperglycemia; Hypothyroidism; Ins

1995
Endocrine and metabolic response to muscarinic stimulation and inhibition in the ruminant: effects of slaframine.
    Journal of animal science, 1995, Volume: 73, Issue:12

    Topics: Alkaloids; Animals; Blood Glucose; Endocrine Glands; Fatty Acids, Nonesterified; Female; Goat Diseas

1995
Effect of triiodothyronine on muscle cell differentiation and blood glucose level in hyperglycemic KK mice.
    Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3

    Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Cell Differentiation; Diabetes Mellitus, Type 2; Gl

1997
Plasma free tryptophan, brain serotonin, and an endocrine profile of the genetically obese hyperglycemic mouse at 4--5 months of age.
    Endocrinology, 1979, Volume: 105, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Brain; Fasting; Glucagon; Hormones; Hyperglycem

1979
Influence of age on the endocrine-metabolic response to surgery.
    Annals of surgery, 1979, Volume: 190, Issue:6

    Topics: Adult; Age Factors; Aged; Aldosterone; Anesthesia, General; Electrolytes; Endocrine Glands; Hernia,

1979
Regulation of hepatic fatty acid synthetase in the obese-hyperglycemic mutant mouse.
    Biochimica et biophysica acta, 1975, Nov-21, Volume: 409, Issue:2

    Topics: Animals; Fatty Acid Synthases; Half-Life; Hyperglycemia; Liver; Mice; Mice, Inbred C57BL; Mice, Obes

1975
Food deprivation suppresses stress-induced rise in catabolic hormones with a concomitant tendency to potentiate the increment of blood glucose.
    Physiology & behavior, 1990, Volume: 48, Issue:4

    Topics: Animals; Blood Glucose; Female; Food Deprivation; Hormones; Hydrocortisone; Hyperglycemia; Sheep; St

1990
Hormone release from thyrotrophs and lactotrophs during hypo- and hyperglycemia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:9

    Topics: Adult; Female; Humans; Hyperglycemia; Hypoglycemia; Insulin; Male; Pituitary Gland, Anterior; Prolac

1989
Effect of hyperglycemia on serum T4 and T3 levels in rats.
    Experimental and clinical endocrinology, 1987, Volume: 90, Issue:1

    Topics: Animals; Glucose; Hyperglycemia; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Thyroxine

1987
Mechanism of bromocriptine-induced hyperglycaemia.
    Life sciences, 1985, Feb-25, Volume: 36, Issue:8

    Topics: Adrenalectomy; Animals; Bromocriptine; Corticosterone; Hyperglycemia; Insulin; Liver Glycogen; Male;

1985
Endocrine manifestations of diphenylhydantoin therapy.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Alkaline Phosphatase; Blood Glucose; End

1974
Impairment of hyperglycemic induced growth hormone suppression in hyperthyroidism.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:11

    Topics: Blood Glucose; Catecholamines; Growth Hormone; Humans; Hyperglycemia; Hyperthyroidism; Hypothalamo-H

1968