Page last updated: 2024-10-25

diazepam and Hyperglycemia

diazepam has been researched along with Hyperglycemia in 12 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"The benzodiazepine anxiolytic diazepam did not affect immobilization-elicited hyperglycemia, although a high dose increased blood glucose levels in normal mice."7.70Effects of anxiolytics, diazepam and tandospirone, on immobilization stress-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 1998)
"Diazepam-elicited hyperglycemia in mice was inhibited by adrenalectomy and the catecholamine synthesis inhibitor alpha-methyl-p-tyrosine, although it was unaffected by pretreatment with the corticosterone synthesis inhibitor dexamethasone."7.70Involvement of adrenaline in diazepam-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 2000)
"Since hyperglycemia was not abolished by adrenalectomy and/or hypophysectomy, a hypothesis is presented to explain how central accumulation of acetylcholine might cause hyperglycemia."5.25Evidence of central influences on blood glucose level: malathion hyperglycemia. ( Korner, M; Ramu, A, 1975)
"The benzodiazepine anxiolytic diazepam did not affect immobilization-elicited hyperglycemia, although a high dose increased blood glucose levels in normal mice."3.70Effects of anxiolytics, diazepam and tandospirone, on immobilization stress-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 1998)
"Diazepam-elicited hyperglycemia in mice was inhibited by adrenalectomy and the catecholamine synthesis inhibitor alpha-methyl-p-tyrosine, although it was unaffected by pretreatment with the corticosterone synthesis inhibitor dexamethasone."3.70Involvement of adrenaline in diazepam-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 2000)
" Malathion (500 mg/kg, ip) inhibited acetylcholinesterase (AchE) activity in RBC and brain and produced hyperglycemia and hyperlactacidemia with depletion of glycogen in liver, triceps, and brain of animals 2 hr after its administration."3.68Effectiveness of certain drugs in acute malathion intoxication in rats. ( Ansari, RA; Husain, K, 1990)
" Rats with the same degree of hyperglycemia, treated after ischemia with pentobarbital (75-95 mg/kg) or diazepam (10-13 mg/kg), survived the observation period of 21 days and recovered, albeit incompletely."3.66Improvement of restitution from cerebral ischemia in hyperglycemic rats by pentobarbital or diazepam. ( Siemkowicz, E, 1980)
"Tramadol is a synthetic opioid and poisoning is increasing around the world day by day."1.62Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study). ( Amirabadizadeh, A; Askari, M; Farrokhfall, K; Foadoddini, M; Mehrpour, O; Miri-Moghaddam, E; Nakhaee, S, 2021)
"Since hyperglycemia was not abolished by adrenalectomy and/or hypophysectomy, a hypothesis is presented to explain how central accumulation of acetylcholine might cause hyperglycemia."1.25Evidence of central influences on blood glucose level: malathion hyperglycemia. ( Korner, M; Ramu, A, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Nakhaee, S1
Farrokhfall, K1
Miri-Moghaddam, E1
Askari, M1
Amirabadizadeh, A1
Foadoddini, M1
Mehrpour, O1
Dhanani, LY1
Totton, RR1
Jara-Quijada, E1
Pérez-Won, M1
Tabilo-Munizaga, G1
Lemus-Mondaca, R1
González-Cavieres, L1
Palma-Acevedo, A1
Herrera-Lavados, C1
Milovanovic, S1
Grzegorczyk, A1
Świątek, Ł1
Grzęda, A1
Dębczak, A1
Tyskiewicz, K1
Konkol, M1
Li, Y2
Chang, P1
Sankaran, S1
Jang, H1
Nie, Y1
Zeng, A1
Hussain, S1
Wu, JY1
Chen, X2
Shi, L2
Senapati, A1
Chetri, BK1
Mitra, S1
Shelke, RG1
Rangan, L1
Chauhan, AS1
Tiwari, M1
Indoliya, Y1
Mishra, SK1
Lavania, UC1
Chauhan, PS1
Chakrabarty, D1
Tripathi, RD1
Akaputra, R1
Hatta, M1
Massi, MN1
Djaharuddin, I1
Bukhari, A1
Aminuddin, A1
Santoso, A1
Natzir, R1
Bahar, B1
Fachri, M1
Farsida, F1
Fathimah, A1
Ubaidah, FM1
Sridiana, E1
Dwiyanti, R1
Syukri, A1
Junita, AR1
Febrianti, A1
Primaguna, MR1
Azhar, A1
Rajaure, YS1
Thapa, B1
Budhathoki, L1
Rana, SR1
Khadka, M1
Batchu, UR1
Surapaneni, JR1
Cheemalamarri, C1
Mandava, K1
Puvvada, N1
Shetty, PR1
Mv, S1
Ranjbarian, P1
Goudarzi, F1
Akya, A1
Heidarinia, H1
Farasat, A1
Rostamian, M1
Suri, K1
Rajput, N1
Sharma, P1
Omble, AD1
Kulkarni, K1
Gahlay, GK1
Fernandez Garcia, E1
Paudel, U1
Noji, MC1
Bowman, CE1
Rustgi, AK1
Pitarresi, JR1
Wellen, KE1
Arany, Z1
Weissenrieder, JS1
Foskett, JK1
Lee, MS1
Han, HJ1
Choi, TI1
Lee, KH1
Baasankhuu, A1
Kim, HT1
Kim, CH1
Redd, PS1
Payero, L1
Gilbert, DM1
Page, CA1
King, R1
McAssey, EV1
Bodie, D1
Diaz, S1
Hancock, CN1
Lee, HS1
Jung, S1
Lee, SW1
Kim, YT1
Lee, J1
Ren, T1
Yu, Z1
Yu, H1
Deng, K1
Wang, Z1
Li, X1
Wang, H1
Wang, L2
Xu, Y1
Lascano, J1
Riley, L1
Khodayari, N1
Brantly, M1
Gupta, R1
Pradhan, J1
Haldar, A1
Murapaka, C1
Chandra Mondal, P1
Gao, R1
Dai, TY1
Meng, Z1
Sun, XF1
Liu, DX1
Shi, MM1
Li, HR1
Kang, X1
Bi, B1
Zhang, YT1
Xu, TW1
Yan, JM1
Jiang, Q1
Helmchen, G1
Guo, H1
Xiang, W1
Fang, Y1
Li, J4
Lin, Y1
An, X1
Jiang, D1
Cao, Q1
Xu, F1
Shiigi, H1
Wang, W1
Chen, Z1
Akosman, I1
Kumar, N1
Mortenson, R1
Lans, A1
De La Garza Ramos, R1
Eleswarapu, A1
Yassari, R1
Fourman, MS1
Jana, S1
Evans, EGB1
Jang, HS1
Zhang, S2
Zhang, H1
Rajca, A1
Gordon, SE1
Zagotta, WN1
Stoll, S1
Mehl, RA1
Miller, S1
Lee, DA1
Muhimpundu, S1
Maxwell, CA1
Liu, Z1
Shen, F1
Tong, Q1
Tang, M1
Peng, M1
Jiao, Z1
Jiang, Y1
Ao, L1
Fu, W1
Lv, X1
Jiang, G1
Hou, L1
Tu, WC1
McManamen, AM1
Su, X1
Jeacopello, I1
Takezawa, MG1
Hieber, DL1
Hassan, GW1
Lee, UN1
Anana, EV1
Locknane, MP1
Stephenson, MW1
Shinkawa, VAM1
Wald, ER1
DeMuri, GP1
Adams, KN1
Berthier, E1
Thongpang, S1
Theberge, AB1
Jiang, L1
Li, Z1
Dong, Q1
Rong, X1
Dong, G1
Huang, J1
Liang, Y1
Sun, S1
Zhang, R1
Miao, Z1
Senju, C1
Nakazawa, Y1
Oso, T1
Shimada, M1
Kato, K1
Matsuse, M1
Tsujimoto, M1
Masaki, T1
Miyazaki, Y1
Fukushima, S1
Tateishi, S1
Utani, A1
Murota, H1
Tanaka, K1
Mitsutake, N1
Moriwaki, S1
Nishigori, C1
Ogi, T1
Liu, C1
Zhang, X1
Wang, B1
Luo, Z1
Qian, D1
Liu, J1
Waterhouse, GIN1
Barbosa, M1
Marques-Sá, J1
Carvalho, C1
Fernandes, V1
Grilli, D1
Smetana, V1
Ahmed, SJ1
Shtender, V1
Pani, M1
Manfrinetti, P1
Mudring, AV1
Kuang, Y1
Yang, D1
Gai, S1
He, F1
An, B1
Yang, P1
Notini, L1
Schulz, K1
Kubeneck, LJ1
Grigg, ARC1
Rothwell, KA1
Fantappiè, G1
ThomasArrigo, LK1
Kretzschmar, R1
Siswanto, FM1
Okukawa, K1
Tamura, A1
Oguro, A1
Imaoka, S1
Kim, CG1
Jung, M1
Kim, HS1
Lee, CK1
Jeung, HC1
Koo, DH1
Bae, WK1
Zang, DY1
Kim, BJ1
Kim, H1
Yun, UJ1
Che, J1
Park, S1
Kim, TS1
Kwon, WS1
Park, J1
Cho, SW1
Nam, CM1
Chung, HC1
Rha, SY1
Colombo, N1
Van Gorp, T1
Matulonis, UA1
Oaknin, A1
Grisham, RN1
Fleming, GF1
Olawaiye, AB1
Nguyen, DD1
Greenstein, AE1
Custodio, JM1
Pashova, HI1
Tudor, IC1
Lorusso, D1
Zhou, F1
Jiang, Z1
Liang, H1
Ru, S1
Bettiol, AA1
Gao, W1
Lipsyc-Sharf, M1
Jain, E1
Collins, LC1
Rosenberg, SM1
Ruddy, KJ1
Tamimi, RM1
Schapira, L1
Come, SE1
Peppercorn, JM1
Borges, VF1
Warner, E1
Snow, C1
Krop, IE1
Kim, D1
Weiss, J1
Zanudo, JGT1
Partridge, AH1
Wagle, N1
Waks, AG1
Moskowitz, A1
Berg, KM1
Grossestreuer, AV1
Balaji, L1
Liu, X1
Cocchi, MN1
Chase, M1
Gong, MN1
Gong, J1
Parikh, SM1
Ngo, L1
Berlin, N1
Donnino, MW1
Zhou, Y1
Chen, Q1
Zhong, S1
Liu, H1
Koh, K1
Chen, H1
He, J1
Chen, J1
Liu, S1
Lin, L1
Zhang, Y1
Xiao, S1
Cao, S1
Yan, B2
Deng, J1
Gu, J1
Tao, Y1
Huang, C1
Lai, C1
Yong, Q1
Shen, Y1
Gong, Z1
Cao, J1
Mao, W1
Yao, Y1
Zhao, J1
Li, Q1
Liu, K1
Liu, B1
Feng, S1
Chandran, V1
Kunjan, C1
Veerapandian, V1
Kannan, R1
Zhang, T1
von Gunten, U1
Caruso, FR1
Goulart, CDL1
Jr, JCB1
de Oliveira, CR1
Mendes, RG1
Arena, R1
Borghi-Silva, A1
Carrasco-Nuñes, N1
Romano, M1
Cabeza, M1
Jiang, B1
Chen, D1
Zhao, C1
Ma, Y1
Yang, W1
Shen, X1
Satheeshkumar, K1
Saravanakumar, P1
Kalavathi, A1
Vennila, KN1
Elango, KP1
Mues Genannt Koers, L1
Prevost, D1
Paulssen, E1
Hoehr, C1
Ulhassan, Z1
Yang, S1
He, D1
Khan, AR1
Salam, A1
Azhar, W1
Muhammad, S1
Ali, S1
Hamid, Y1
Khan, I1
Sheteiwy, MS1
Zhou, W1
Wang, X1
Xie, Q1
Wang, Y1
Lü, H1
Fu, M1
Wang, D1
Siemkowicz, E1
Sugimoto, Y2
Yamada, J2
Noma, T2
Ramu, A1
Korner, M1
Husain, K1
Ansari, RA1
Michael, CA1
Kersh, ES1
Schwartz, LK1
Mottram, PE1
Johnson, PB1
Hoffman, JE1
Vapaatalo, H1
Karppanen, H1
de Bonnevaux, SC1
Carrillo, L1

Trials

1 trial available for diazepam and Hyperglycemia

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Sexuality research & social policy : journal of NSRC : SR & SP, 2023, Apr-05

    Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com

2023

Other Studies

11 other studies available for diazepam and Hyperglycemia

ArticleYear
Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study).
    BMC endocrine disorders, 2021, Sep-06, Volume: 21, Issue:1

    Topics: Analgesics, Opioid; Animals; Blood Glucose; Diazepam; Drug Overdose; Hyperglycemia; Hypnotics and Se

2021
Improvement of restitution from cerebral ischemia in hyperglycemic rats by pentobarbital or diazepam.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Animals; Blood Glucose; Diazepam; Hyperglycemia; Ischemic Attack, Transient; Male; Pentobarbital; Ra

1980
Effects of anxiolytics, diazepam and tandospirone, on immobilization stress-induced hyperglycemia in mice.
    Life sciences, 1998, Volume: 63, Issue:14

    Topics: Animals; Anti-Anxiety Agents; Diazepam; Epinephrine; Hyperglycemia; Immobilization; Isoindoles; Male

1998
Involvement of adrenaline in diazepam-induced hyperglycemia in mice.
    Life sciences, 2000, Feb-18, Volume: 66, Issue:13

    Topics: Adrenergic beta-Antagonists; alpha-Methyltyrosine; Animals; Blood Glucose; Diazepam; Epinephrine; Hy

2000
Evidence of central influences on blood glucose level: malathion hyperglycemia.
    European journal of pharmacology, 1975, Volume: 32, Issue:1

    Topics: Acetylcholine; Adrenalectomy; Animals; Atropine; Blood Glucose; Brain; Cholinesterases; Depression,

1975
Effectiveness of certain drugs in acute malathion intoxication in rats.
    Ecotoxicology and environmental safety, 1990, Volume: 19, Issue:3

    Topics: Acidosis, Lactic; Animals; Atropine; Brain; Butanones; Cholinesterase Inhibitors; Cholinesterase Rea

1990
Intravenous diazoxide in the treatment of severe pre-eclamptic toxaemia and eclampsia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1973, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Delivery, Obstetric; Diazepam; Diazoxide; Eclampsia; Female; Fetal Death; Humans;

1973
Narcotic poisoning: an epidemic disease.
    American family physician, 1973, Volume: 8, Issue:6

    Topics: Diazepam; Glucose; Hospitalization; Humans; Hyperglycemia; Methadone; Myelitis, Transverse; Myoglobi

1973
Isoniazid toxicity. Reversal with pyridoxine.
    Minnesota medicine, 1974, Volume: 57, Issue:2

    Topics: Adolescent; Diazepam; Humans; Hyperglycemia; Hypothermia; Isoniazid; Lactates; Male; Pyridoxine; Sei

1974
Blood glucose, serum GOT and tissue catecholamines in rats after combined ethanol-tranquilizer administration.
    Agents and actions, 1970, Volume: 1, Issue:4

    Topics: Adrenal Glands; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Catecholamines; Chlormet

1970
Autonomic response to pentamethylenetetrazol following trimetadione and benzodiazepines administration.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1

    Topics: Animals; Anticonvulsants; Autonomic Nervous System; Blood Glucose; Blood Pressure; Chlordiazepoxide;

1968