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chlorpropamide and Hyperglycemia

chlorpropamide has been researched along with Hyperglycemia in 21 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of hyperglycemia on normal islets, rats were made diabetic by a 95% partial pancreatectomy and treated with insulin, saline, or chlorpropamide for 3 mo."7.66Islet changes induced by hyperglycemia in rats. Effect of insulin or chlorpropamide therapy. ( Bown, E; Clark, A; King, T; Turner, RC; Vanhegan, RI, 1982)
"To investigate the effect of hyperglycemia on normal islets, rats were made diabetic by a 95% partial pancreatectomy and treated with insulin, saline, or chlorpropamide for 3 mo."3.66Islet changes induced by hyperglycemia in rats. Effect of insulin or chlorpropamide therapy. ( Bown, E; Clark, A; King, T; Turner, RC; Vanhegan, RI, 1982)
" Recent evidence indicates that hyperglycemia in diabetic patients, but not in normal subjects, is characterized by elevations of circulating levels of arginine vasopressin (AVP; antidiuretic hormone, ADH)."3.66Water metabolism in diabetes mellitus. ( Davis, FB; Davis, PJ, 1981)
"Treatment with chlorpropamide (one to three months, average dose equals 375 mg/day) was associated with a marked reduction in hyperglycemia and an increase toward normal in insulin binding to mononuclear cells."1.26Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients. ( Olefsky, JM; Reaven, GM, 1976)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199021 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeung, JM1
Knaus, EE1
BRIGANTE, JC1
LEVINE, R1
SMITH, M1
FOGLIA, VG1
YABO, R1
RODARI, T1
MAGGI, G1
SPECCHIA, G1
Czyzyk, A1
Ooms, HA1
Wodon, C1
Christophe, J1
Clark, A1
Bown, E1
King, T1
Vanhegan, RI1
Turner, RC2
Best, JD1
Judzewitsch, RG1
Pfeifer, MA1
Beard, JC1
Halter, JB1
Porte, D1
Kanefsky, TM1
Medoff, SJ1
Davis, FB1
Davis, PJ1
Olefsky, JM1
Reaven, GM2
Fajans, SS1
Cloutier, MC1
Crowther, RL1
Richards, P1
Pacuła, P1
Janeczko, E1
Trusiewicz, D1
Koneczna, A1
Tomaszczyk, M1
Dembe, K1
Stryjek-Kamińska, D1
Hosker, JP1
Burnett, MA1
Davies, EG1
Harris, EA1
Felber, JP1
Mehnert, H1
Coppi, G1
Bonardi, G1
Ravid, M1
Rubinstein, E1
Cabili, S1
Vorona, MI1
Genes, SG1
Grinchenko, TS1
Kopelovich, MA1
Lobanovskaia, LI1

Reviews

1 review available for chlorpropamide and Hyperglycemia

ArticleYear
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
    Schweizerische medizinische Wochenschrift, 1979, Dec-01, Volume: 109, Issue:46

    Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromo

1979

Other Studies

20 other studies available for chlorpropamide and Hyperglycemia

ArticleYear
Synthesis of N-(3,6-dihydro-1(2H)-pyridinyl)benzamides with hyperglycemic-hypoglycemic activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Benzamides; Blood Glucose; Hyperglycemia; Hypoglycemic Agents; Indicators and Reagents; Mag

1987
[Chloropropamide in rats with endocrine insufficiencies and glucose tolerance].
    La Semana medica, 1963, Jan-03, Volume: 122

    Topics: Animals; Chlorpropamide; Glucose; Glucose Tolerance Test; Hyperglycemia; Hypophysectomy; Pancreas; R

1963
ORAL HYPOGLYCEMIC AGENTS.
    The Journal-lancet, 1963, Volume: 83

    Topics: Chlorpropamide; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Phenformin

1963
[ACTION OF CHLORPROPAMIDE ON NORMAL, PREDIABETIC AND DIABETIC RATS].
    Acta physiologica latino americana, 1964, Volume: 14

    Topics: Animals; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Experimental

1964
[Behavior of the double venous hyperglycemia test in diabetic subjects after prolonged treatment with chlorpropamide].
    Bollettino della Societa italiana di biologia sperimentale, 1961, Dec-15, Volume: 37

    Topics: Chlorpropamide; Diabetes Mellitus; Hyperglycemia; Hypoglycemic Agents; Veins

1961
[Hypoaminoacidemia in the dog after rapid intravenous injection of L-leucine].
    Revue francaise d'etudes cliniques et biologiques, 1967, Volume: 12, Issue:8

    Topics: Amino Acids; Animals; Biological Transport, Active; Blood Glucose; Chlorpropamide; Dogs; Glucose; Hy

1967
Islet changes induced by hyperglycemia in rats. Effect of insulin or chlorpropamide therapy.
    Diabetes, 1982, Volume: 31, Issue:4 Pt 1

    Topics: Animals; Blood Glucose; Body Weight; Chlorpropamide; Dogs; Hyperglycemia; Insulin; Islets of Langerh

1982
The effect of chronic sulfonylurea therapy on hepatic glucose production in non-insulin-dependent diabetes.
    Diabetes, 1982, Volume: 31, Issue:4 Pt 1

    Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glucose; Humans; Hyperglycemi

1982
Stevens-Johnson syndrome and neutropenia with chlorpropamide therapy.
    Archives of internal medicine, 1980, Volume: 140, Issue:11

    Topics: Aged; Agranulocytosis; Chlorpropamide; Female; Humans; Hyperglycemia; Neutropenia; Stevens-Johnson S

1980
Water metabolism in diabetes mellitus.
    The American journal of medicine, 1981, Volume: 70, Issue:1

    Topics: Arginine Vasopressin; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus; Diabetic Nephropathies;

1981
Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients.
    The American journal of medicine, 1976, Volume: 60, Issue:1

    Topics: Adult; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hyperglycemia; Insulin; Insulin Resistance

1976
Drug-induced metabolic disease.
    British medical journal, 1979, Apr-28, Volume: 1, Issue:6171

    Topics: Anti-Inflammatory Agents; Antidepressive Agents; Chlorpropamide; Diabetes Mellitus; Diuretics; Gout;

1979
[Evaluation of the late ineffectiveness of sulfonylurea derivatives in patients with diabetes mellitus hospitalized at the Gastroenterology and Metabolic Disease Clinic, Medical Academy, in Warsaw 1976-1987].
    Polskie Archiwum Medycyny Wewnetrznej, 1989, Volume: 81, Issue:4

    Topics: Adult; Age Factors; Aged; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy,

1989
Beneficial effect of moderate weight loss in older patients with non-insulin-dependent diabetes mellitus poorly controlled with insulin.
    Journal of the American Geriatrics Society, 1985, Volume: 33, Issue:2

    Topics: Aged; Body Weight; Chlorpropamide; Diabetes Mellitus, Type 2; Diet, Diabetic; Diet, Reducing; Female

1985
Sulphonylurea therapy doubles B-cell response to glucose in type 2 diabetic patients.
    Diabetologia, 1985, Volume: 28, Issue:11

    Topics: Aged; Blood Glucose; C-Peptide; Chlorpropamide; Diabetes Mellitus, Type 2; Glucose; Glyburide; Human

1985
Clinical use of radioimmunological plasma insulin assessment.
    Klinische Wochenschrift, 1973, Jan-15, Volume: 51, Issue:2

    Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet; Glucose Toleranc

1973
[Letter: Posthypoglycemic hyperglycemia].
    Deutsche medizinische Wochenschrift (1946), 1974, Mar-22, Volume: 99, Issue:12

    Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Insulin; Tolbut

1974
[Action of tolbutamide, chlorpropamide and insulin on hyperglycemia induced by non-thiazide diuretics in rats].
    Bollettino della Societa italiana di biologia sperimentale, 1969, Jan-31, Volume: 45, Issue:2

    Topics: Animals; Chlorpropamide; Chlorthalidone; Diuretics; Ethacrynic Acid; Female; Furosemide; Hyperglycem

1969
Anaphylactic reaction to chlorpropamide.
    British medical journal, 1971, Jul-17, Volume: 3, Issue:5767

    Topics: Anaphylaxis; Antibodies; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Humans; Hyperglycemia; Im

1971
[The therapeutic efficacy of saccharoreducing preparation chlorcyclamide].
    Klinicheskaia meditsina, 1968, Volume: 46, Issue:9

    Topics: Adult; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hyperglycemia; Hypoglycemic Agents; Male;

1968