Page last updated: 2024-08-07 13:40:18
Neutral alpha-glucosidase C
A neutral alpha-glucosidase C that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8TET4]
Synonyms
EC 3.2.1.20
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| homonojirimycin | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
Enables
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| alpha-1,4-glucosidase activity | molecular function | Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. [EC:3.2.1.20] |
| carbohydrate binding | molecular function | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah] |
| maltose alpha-glucosidase activity | molecular function | Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose. [MetaCyc:RXN-2141] |
Involved In
This protein is involved in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| maltose metabolic process | biological process | The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch. [GOC:jl, ISBN:0198506732] |
| N-glycan processing | biological process | The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. [ISBN:0879695595, PMID:12736198] |