Page last updated: 2024-08-07 13:40:18

Neutral alpha-glucosidase C

A neutral alpha-glucosidase C that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8TET4]

Synonyms

EC 3.2.1.20

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (1)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
homonojirimycinHomo sapiens (human)IC5080.000011

Enables

This protein enables 3 target(s):

TargetCategoryDefinition
alpha-1,4-glucosidase activitymolecular functionCatalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. [EC:3.2.1.20]
carbohydrate bindingmolecular functionBinding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah]
maltose alpha-glucosidase activitymolecular functionCatalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose. [MetaCyc:RXN-2141]

Involved In

This protein is involved in 2 target(s):

TargetCategoryDefinition
maltose metabolic processbiological processThe chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch. [GOC:jl, ISBN:0198506732]
N-glycan processingbiological processThe conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. [ISBN:0879695595, PMID:12736198]