Compounds > 5-(4-phenylbutoxy)psoralen
Page last updated: 2024-08-02 04:19:07

5-(4-phenylbutoxy)psoralen

Description

5-(4-phenylbutoxy)psoralen: structure in first source [MeSH]

psora 4 : A member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM). [CHeBI]

Cross-References

ID SourceID
PubMed CID6603977
CHEMBL ID1256851
SCHEMBL ID2801777
CHEBI ID183514
MeSH IDM0483786

Synonyms (36)

Synonym
EU-0100137
psora-4, >=98% (hplc)
NCGC00015863-01 ,
lopac-p-9872
NCGC00093627-01
psora-4
NCGC00093627-02
NCGC00015863-02
NCGC00015863-04
5-(4-phenylbutoxy)psoralen
4-(4-phenylbutoxy)-7h-furo[3,2-g]chromen-7-one
psora 4
4-(4-phenylbutoxy)-7h-furo[3,2-g][1]benzopyran-7-one
724709-68-6
CHEBI:183514
4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one
HMS3260K16
CHEMBL1256851 ,
bdbm50331458
CCG-204232
NCGC00015863-03
LP00137
tox21_500137
NCGC00260822-01
SCHEMBL2801777
DTXSID10424970
AKOS024458119
SR-01000075478-1
sr-01000075478
gtpl9583
phenolphthalein diphosphate tetrasodium
SDCCGSBI-0050125.P002
CS-0029231
HY-108583
QDY3FLF2DY
7h-furo[3,2-g][1]benzopyran-7-one, 4-(4-phenylbutoxy)-

Roles (3)

RoleDescription
geroprotectorAny compound that supports healthy aging, slows the biological aging process, or extends lifespan.
potassium channel blockerAn agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
immunosuppressive agentAn agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.

Drug Classes (3)

ClassDescription
benzenesAny benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
aromatic etherAny ether in which the oxygen is attached to at least one aryl substituent.
psoralensA furanocoumarin with a 7H-furo[3,2-g]chromen-7-one skeleton and its substituted derivatives thereof.

Protein Targets (44)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Chain A, HADH2 proteinHomo sapiens (human)Potency19.7830AID886; AID893
Chain B, HADH2 proteinHomo sapiens (human)Potency19.7830AID886; AID893
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency35.4813AID2147
Chain A, Ferritin light chainEquus caballus (horse)Potency50.1187AID2323
Chain A, CruzipainTrypanosoma cruziPotency12.5893AID1476
endonuclease IVEscherichia coliPotency11.2202AID1708
NFKB1 protein, partialHomo sapiens (human)Potency0.4467AID895; AID928
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency31.6228AID1030
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency25.1189AID914; AID915
thyroid stimulating hormone receptorHomo sapiens (human)Potency25.1189AID926; AID938
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency18.0459AID1224819; AID1224820
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency25.1376AID504332
Bloom syndrome protein isoform 1Homo sapiens (human)Potency25.1189AID2364; AID2528
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency0.0501AID891
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency3.0131AID1967
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.0631AID899
cytochrome P450 2C9 precursorHomo sapiens (human)Potency0.1000AID883
chromobox protein homolog 1Homo sapiens (human)Potency17.7828AID488953
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency22.3872AID588834
mitogen-activated protein kinase 1Homo sapiens (human)Potency7.9874AID1454; AID995
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency0.3981AID884; AID885
M-phase phosphoprotein 8Homo sapiens (human)Potency19.4201AID488949
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency9.0532AID943; AID944
lamin isoform A-delta10Homo sapiens (human)Potency8.4218AID1459; AID1487
neuropeptide S receptor isoform AHomo sapiens (human)Potency12.5893AID1461
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency0.3981AID885
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency0.1000AID883
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency0.3981AID885
GABA theta subunitRattus norvegicus (Norway rat)Potency0.3981AID885
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency0.3981AID885
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency8.4921AID485368

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)IC500.7240AID539299

Bioassays (32)

Assay IDTitleYearJournalArticle
AID588378qHTS for Inhibitors of ATXN expression: Validation2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60ISSN: 1873-3913A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
ISSN: 1946-6242		Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490		Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
ISSN: 1946-6242		Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
ISSN: 2211-1247		A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
ISSN: 1554-8937		High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
ISSN: 0021-9258		Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
ISSN: 1946-6242		Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID524795Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID524791Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID524793Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID726085Selectivity ratio of EC50 for mouse voltage-gated K channel 1.3 to EC50 for mouse voltage-gated K channel 1.12013Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
ISSN: 1520-4804		Ion channels as therapeutic targets: a drug discovery perspective.
AID726080Selectivity ratio of EC50 for mouse voltage-gated K channel 1.3 to EC50 for rat voltage-gated K channel 1.22013Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
ISSN: 1520-4804		Ion channels as therapeutic targets: a drug discovery perspective.
AID539299Inhibition of human voltage-gated potassium channel Kv1.3 expressed in CGE22 cells by patch clamp assay2010Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23
ISSN: 1464-3405		N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.
AID524790Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID726079Selectivity ratio of EC50 for mouse voltage-gated K channel 1.3 to EC50 for mouse voltage-gated K channel 1.72013Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
ISSN: 1520-4804		Ion channels as therapeutic targets: a drug discovery perspective.
AID726081Selectivity ratio of EC50 for mouse voltage-gated K channel 1.3 to EC50 for human voltage-gated K channel 1.42013Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3
ISSN: 1520-4804		Ion channels as therapeutic targets: a drug discovery perspective.
AID524794Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID524796Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID524792Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
ISSN: 1552-4469		Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
ISSN: 1552-454X		A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2022Journal of enzyme inhibition and medicinal chemistry, Dec, Volume: 37, Issue:1
ISSN: 1475-6374
AID1346697Human Kv1.3 (Voltage-gated potassium channels)2010Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23
ISSN: 1464-3405		N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.

Research

Studies (35)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (14.29)29.6817
2010's21 (60.00)24.3611
2020's9 (25.71)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (2.86%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other34 (97.14%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
3-phenylpropionic acid
0
benzenes;
monocarboxylic acid		antifungal agent;
human metabolite;
plant metabolite		00low000000
benzene
0
aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent		00low000000
phenylacetic acid
0
benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin		00low000000
gallopamil
0
benzenes;
organic amino compound		00low000000
mandelic acid
0
2-hydroxy monocarboxylic acid;
benzenes		antibacterial agent;
human xenobiotic metabolite		00low000000
4-phenyl-3-furoxancarbonitrile
0
1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
bencyclane
0
benzenes00low000000
benzamidine
0
benzenes;
carboxamidine		serine protease inhibitor00low000000
benzyl isothiocyanate
0
benzenes;
isothiocyanate		antibacterial drug00low000000
benzylhydrochlorothiazide
0
benzenes;
benzothiadiazine;
organochlorine compound;
secondary amino compound;
sulfonamide		00low000000
carbetapentane
0
benzenes00low000000
carbidopa
0
benzenes;
monocarboxylic acid		00low000000
cetraxate
0
benzenes;
monocarboxylic acid		00low000000
chlorpropham
0
benzenes;
carbamate ester;
monochlorobenzenes		herbicide;
plant growth retardant		00low000000
cimaterol
0
benzenes;
nitrile		00low000000
clofilium
0
benzenes;
organic amino compound		00low000000
diphenidol
0
benzenes;
piperidines;
tertiary alcohol		antiemetic00low000000
cycloadiphenine
0
benzenes00low000000
fenipentol
0
benzenes00low000000
2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1,1-dimethyl-3-pyrrolidin-1-iumyl) ester
0
benzenes00low000000
lidocaine
0
benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic		00low000000
isocarboxazid
0
benzenes00low000000
labetalol
0
benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound		00low000000
methadone
0
benzenes;
diarylmethane;
ketone;
tertiary amino compound		00low000000
3-Hydroxy-alpha-methyl-DL-tyrosine
0
benzenes;
monocarboxylic acid		00low000000
metolachlor
0
aromatic amide;
benzenes;
ether;
organochlorine compound		00low000000
nafoxidine
0
benzenes;
naphthalenes;
ring assembly		00low000000
nicardipine
0
benzenes;
C-nitro compound;
diester;
dihydropyridine;
methyl ester;
tertiary amino compound		00low000000
phenprobamate
0
benzenes00low000000
sulfabenzamide
0
benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug		00low000000
sulfacytine
0
benzenes;
sulfonamide		00low000000
sulfamonomethoxine
0
benzenes;
sulfonamide		00low000000
sulfaquinoxaline
0
benzenes;
sulfonamide		00low000000
2-phenylcyclopropan-1-amine
0
benzenes;
cyclopropanes;
primary amine		00low000000
tyropanoate
0
benzenes;
monocarboxylic acid		00low000000
tolazoline hydrochloride
0
benzenes00low000000
phenylethyl alcohol
0
benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite		00low000000
mebanazine
0
benzenes00low000000
phencyclidine
0
benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug		00low000000
caramiphen
0
benzenes00low000000
acetyl sulfisoxazole
0
benzenes;
sulfonamide		00low000000
2-phenylbutyric acid
0
benzenes;
monocarboxylic acid		human xenobiotic metabolite00low000000
diphenyl
0
aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative		00low000000
styrene glycol
0
benzenes00low000000
sulfaethidole
0
benzenes;
sulfonamide		00low000000
iophenoxic acid
0
benzenes;
monocarboxylic acid		00low000000
benzotrichloride
0
benzenes;
organochlorine compound;
volatile organic compound		carcinogenic agent00low000000
benzal chloride
0
benzenes00low000000
benzoyl chloride
0
acyl chloride;
benzenes		carcinogenic agent00low000000
benzonitrile
0
benzenes;
nitrile		00low000000
methylphenylsulfide
0
aryl sulfide;
benzenes		00low000000
methyl phenylacetate
0
benzenes00low000000
ethyl phenylacetate
0
benzenes00low000000
phenyl isocyanate
0
benzenes;
isocyanates		allergen;
hapten		00low000000
3-phenylpropanal
0
aldehyde;
benzenes		flavouring agent;
plant metabolite		00low000000
1,4-diethylbenzene
0
benzenes00low000000
benzyl cyanide
0
benzenes;
nitrile		animal metabolite;
pheromone		00low000000
pivalylbenzhydrazine
0
benzenes00low000000
mexacarbate
0
benzenes00low000000
carbutamide
0
benzenes;
sulfonamide		00low000000
methaphenilene
0
benzenes00low000000
biphenylacetylene
0
arylacetylene;
benzenes		fluorochrome00low000000
beclamide
0
benzenes00low000000
mepiperphenidol
0
benzenes;
organic amino compound		00low000000
glybuthiazol
0
benzenes;
sulfonamide		00low000000
phenylacetylene
0
benzenes00low000000
sulfanilylurea
0
benzenes;
sulfonamide		00low000000
metahexamide
0
benzenes;
sulfonamide		00low000000
nitrosobenzene
0
benzenes;
nitroso compound		xenobiotic metabolite00low000000
triphenylphosphine
0
benzenes;
tertiary phosphine		NMR chemical shift reference compound;
reducing agent		00low000000
2-cyanophenol
0
benzenes;
nitrile		00low000000
bensulide
0
benzenes00low000000
1-phenylcyclohex-1-ene
0
benzenes00low000000
diphenyl disulfide
0
benzenes00low000000
2-phenylpropanol
0
benzenes00low000000
methyl phenyl sulfoxide
0
benzenes;
sulfoxide		00low000000
2,6-dimethoxybenzoic acid
0
benzenes;
carbonyl compound		00low000000
phenylphosphonic acid
0
benzenes00low000000
pyrazon
0
benzenes;
organochlorine compound;
primary amino compound;
pyridazinone		environmental contaminant;
herbicide;
xenobiotic		00low000000
3-phenylpropylamine
0
benzenes;
phenylalkylamine;
primary amino compound		00low000000
aminorex
0
benzenes00low000000
5-phenylvaleric acid
0
benzenes;
monocarboxylic acid		00low000000
bitoscanate
0
benzenes00low000000
3-phenylbutyric acid
0
benzenes;
monocarboxylic acid		antibacterial agent;
bacterial xenobiotic metabolite		00low000000
teclozan
0
benzenes00low000000
dioxacarb
0
benzenes00low000000
fenestrel
0
benzenes00low000000
propham
0
benzenes;
carbamate ester		herbicide;
plant growth retardant		00low000000
cyanophenphos
0
benzenes;
nitrile		00low000000
N'-methyl-N,N-diphenylurea
0
benzenes00low000000
dibenzo-18-crown-6
0
benzenes;
crown ether		phase-transfer catalyst00low000000
clobutinol
0
benzenes;
organic amino compound		00low000000
phenyl acetate
0
benzenes;
phenyl acetates		00low000000
ripazepam
0
benzenes00low000000
u 40481
0
benzenes;
formamidines		marine xenobiotic metabolite00low000000
iprodione
0
benzenes;
dichlorophenyl dicarboximide fungicide;
imidazole fungicide;
imidazolidine-2,4-dione;
ureas		antifungal agrochemical;
nematicide		00low000000
clorsulon
0
benzenes;
sulfonamide		00low000000
ibutilide
0
benzenes;
organic amino compound		00low000000
prosulfocarb
0
benzenes;
monothiocarbamic ester		environmental contaminant;
herbicide;
xenobiotic		00low000000
Isopropyl phenylacetate
0
benzenes00low000000
4-methyl-1-phenylpentan-2-ol
0
benzenes00low000000
magnesium salicylate
0
benzenes;
carbonyl compound		00low000000
plerixafor
0
azacycloalkane;
azamacrocycle;
benzenes;
crown amine;
secondary amino compound;
tertiary amino compound		anti-HIV agent;
antineoplastic agent;
C-X-C chemokine receptor type 4 antagonist;
immunological adjuvant		00low000000
tribuzone
0
benzenes00low000000
phenylpropiolic acid
0
acetylenic compound;
alpha,beta-unsaturated monocarboxylic acid;
benzenes		00low000000
2-Oxo-4-phenylbutyric acid
0
benzenes00low000000
emopamil
0
benzenes;
organic amino compound		00low000000
bathophenanthroline
0
benzenes;
phenanthrolines		chelator00low000000
2-aminobenzenesulfonamide
0
benzenes;
sulfonamide		00low000000
3-phenylpropyl isothiocyanate
0
benzenes00low000000
4-chloro-5-sulfamoylanthranilic acid
0
benzenes;
sulfonamide		00low000000
phenylheptatriyne
0
benzenes00low000000
methyl mandelate
0
benzenes00low000000
benzylphosphonic acid
0
benzenes00low000000
9,10-bis(phenylethynyl)anthracene
0
anthracenes;
arylacetylene;
benzenes		fluorochrome00low000000
4-phenylbutylamine
0
benzenes;
phenylalkylamine;
primary amino compound		00low000000
3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid
0
benzenes;
monocarboxylic acid		00low000000
sdds
0
benzenes;
sulfonamide		00low000000
1-hydroxy-1-phenyl-2-propanone
0
benzenes;
methyl ketone;
secondary alpha-hydroxy ketone		00low000000
silomat
0
benzenes;
organic amino compound		00low000000
phenylisopropyladenosine
0
aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent		00low000000
alpha-Cyclohexylmandelic acid
0
benzenes00low000000
1-amino-1-phenylmethyl phosphonic acid
0
benzenes;
phosphonic acids;
primary amino compound		00low000000
alpha-methylphenylalanine
0
benzenes;
monocarboxylic acid		00low000000
piscidic acid
0
benzenes;
monocarboxylic acid		00low000000
mitiglinide
0
benzenes;
monocarboxylic acid		00low000000
n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide
0
benzenes;
coumarins;
maleimides;
tertiary amino compound		fluorescent dye00low000000
4-phenylbutyl isothiocyanate
0
benzenes;
organic amino compound		00low000000
n-acetylphenelzine
0
benzenes00low000000
forasartan
0
benzenes;
pyridines;
tetrazoles;
triazoles		angiotensin receptor antagonist;
antihypertensive agent		00low000000
desethyloxybutynin
0
benzenes00low000000
varespladib
0
aromatic ether;
benzenes;
dicarboxylic acid monoamide;
indoles;
monocarboxylic acid;
primary carboxamide		anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor		00low000000
3,5-dihydroxyphenylpropionic acid
0
benzenes;
monocarboxylic acid		00low000000
fukiic acid
0
benzenes;
monocarboxylic acid		00low000000
monodesmethylcitalopram
0
benzenes;
organic amino compound		00low000000
cyclodrine
0
benzenes00low000000
didesmethylcitalopram
0
benzenes;
organic amino compound		00low000000
carlina oxide
0
benzenes00low000000
4-butyl-4-(hydroxymethyl)-1,2-diphenylpyrazolidine-3,5-dione
0
benzenes00low000000
2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile
0
benzenes;
nitrile		00low000000
benzyl d-glucopyranoside
0
benzenes;
beta-D-glucoside		plant metabolite00low000000
cafenstrole
0
benzenes;
sulfone;
triazoles		agrochemical;
antimitotic;
herbicide		00low000000
(5-Phenyl-1,2,4-triazol-3-yl)urea
0
benzenes00low000000
pifithrin mu
0
benzenes00low000000
2-(2-phenylethyl)chromone
0
benzenes;
chromones		plant metabolite00low000000
bms 214662
0
benzenes;
benzodiazepine;
imidazoles;
nitrile;
sulfonamide;
thiophenes		antineoplastic agent;
apoptosis inducer;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor		00low000000
N-bis(N-methylanilino)phosphoryl-N-methylaniline
0
benzenes00low000000
3-[di(propan-2-yl)phosphorylmethyl]benzonitrile
0
benzenes;
nitrile		00low000000
4,5-diphenyl-1,2,3-triazole
0
benzenes;
ring assembly;
triazoles		00low000000
N-benzylquinazolin-4-amine
0
benzenes;
quinazolines;
secondary amino compound		00low000000
2-acetyl-6-amino-8-(2-phenylethyl)-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile
0
benzenes00low000000
thiobenzamide
0
benzenes00low000000
4-(benzylsulfanyl)thieno[2,3-d]pyrimidine
0
aryl sulfide;
benzenes;
thienopyrimidine		00low000000
4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile
0
benzenes;
nitrile		00low000000
N-methyl-N-phenylthiourea
0
benzenes00low000000
3,6-dibenzyl-1,2-dihydro-1,2,4,5-tetraazine
0
benzenes00low000000
1-cyclohexyl-3-(2-phenylethyl)urea
0
benzenes00low000000
5-ethyl-1-(phenylmethyl)-1,3,5-triazinane-2-thione
0
benzenes00low000000
4-amino-N-(4-ethoxyphenyl)benzenesulfonamide
0
benzenes;
sulfonamide		00low000000
N-[5-(phenylmethyl)-1,3,4-thiadiazol-2-yl]carbamic acid methyl ester
0
benzenes00low000000
1,3-bis(2-phenylethyl)thiourea
0
benzenes00low000000
8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thione
0
benzenes00low000000
3-(4-ethyl-5-methyl-3-thiophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione
0
benzenes00low000000
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione
0
benzenes00low000000
6-(2-phenylethyl)-3-(phenylmethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
0
benzenes;
triazolothiadiazole		00low000000
4-(2-furanylmethyl)-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione
0
benzenes00low000000
4-(1H-imidazol-1-ylmethyl)benzonitrile
0
benzenes;
nitrile		00low000000
N-(3-cyano-5-methyl-4-phenyl-2-thiophenyl)-3,5-dimethyl-4-isoxazolecarboxamide
0
benzenes00low000000
1-amino-3-[3-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea
0
benzenes00low000000
N-(3-phenylpropyl)methanesulfonamide
0
benzenes00low000000
1-ethyl-3-[[[(phenylmethyl)amino]-sulfanylidenemethyl]amino]thiourea
0
benzenes00low000000
N-[[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide
0
benzenes00low000000
amn082
0
benzenes;
diamine;
diarylmethane;
secondary amino compound		metabotropic glutamate receptor agonist;
neuroprotective agent		00low000000
2-(2-furanyl)-3,5-dimethyl-4-oxido-6-phenylpyrazin-1-ium 1-oxide
0
benzenes00low000000
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-phenyl-1,3,4-oxadiazol-2-amine
0
benzenes00low000000
4-butyl-3-(phenylmethyl)-1H-1,2,4-triazole-5-thione
0
benzenes00low000000
N1-phenethylhydrazine-1-carbothioamide
0
benzenes00low000000
1-hydroxy-5,5-dimethyl-2-phenyltetrahydro-4H-imidazole-4-thione
0
benzenes00low000000
2-[1-[2-oxo-2-[(4-thiophen-2-ylphenyl)methylamino]ethyl]cyclohexyl]acetic acid
0
benzenes00low000000
5-[4-(2-furylcarbonyl)piperazino]-5-oxo-3-phenylpentanoic acid
0
benzenes;
monocarboxylic acid		00low000000
N-(cyclopropylmethyl)-N'-phenylurea
0
benzenes00low000000
2-[(4-chlorophenyl)methoxy]-6-methoxybenzonitrile
0
benzenes;
nitrile		00low000000
2-(4-pentylphenyl)acetic acid
0
benzenes00low000000
5-methyl-2-phenyl-5-(2-phenylethyl)-1,2,4-triazolidine-3-thione
0
benzenes00low000000
k 858
0
benzenes00low000000
4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile
0
benzenes;
nitrile		00low000000
9-oxo-N-(1-phenylethyl)-3-bicyclo[3.3.1]nonanecarboxamide
0
benzenes00low000000
N1,N4-bis(1-phenylethyl)cyclohexane-1,4-dicarboxamide
0
benzenes00low000000
4-phenyl-3H-thiazole-2-thione
0
benzenes00low000000
sulfatolamide
0
benzenes;
sulfonamide		00low000000
ifetroban
0
benzenes;
monocarboxylic acid		00low000000
1-[(2-ethyl-4-hydroxy-4-methyl-1-oxopentyl)amino]-3-phenylthiourea
0
benzenes00low000000
2-[6-amino-5-cyano-4-(4-ethylphenyl)-2,4-dihydropyrano[2,3-c]pyrazol-3-yl]acetic acid methyl ester
0
benzenes;
pyranopyrazole		00low000000
3-phenyl-3-(1-tetrazolyl)propanoic acid
0
benzenes;
monocarboxylic acid		00low000000
3,5-dimethyl-N-(2-phenylethyl)-N-(phenylmethyl)-4-isoxazolesulfonamide
0
benzenes00low000000
4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-3-nitrobenzenesulfonamide
0
benzenes;
sulfonamide		00low000000
N'-[5-(phenylmethyl)-4,5-dihydrothiazol-2-yl]hexanehydrazide
0
benzenes00low000000
5-amino-2-(diethylamino)-N-(2-methoxyphenyl)benzenesulfonamide
0
benzenes;
sulfonamide		00low000000
4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione
0
benzenes00low000000
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
0
benzenes;
thiadiazolidine		anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent		00low000000
N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide
0
benzenes00low000000
N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)aniline
0
benzenes;
sulfonamide		00low000000
1-(1-adamantyl)-3-[1-(phenylmethyl)-4-pyrazolyl]urea
0
benzenes00low000000
neticonazole
0
aromatic ether;
benzenes;
conazole antifungal drug;
enamine;
imidazole antifungal drug;
imidazoles;
methyl sulfide		antifungal drug;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor		00low000000
l796778
0
benzenes;
C-nitro compound;
L-lysine derivative;
L-phenylalanine derivative;
methyl ester;
oligopeptide;
secondary carboxamide;
ureas		somatostatin receptor agonist00low000000
l803087
0
benzenes;
fluoroindole;
guanidines;
L-arginine derivative;
methyl ester;
phenylindole;
secondary carboxamide		somatostatin receptor agonist00low000000
ro 4-6790
0
benzenes;
sulfonamide		00low000000
bay 11-7085
0
benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor		00low000000
gluconasturtiin
0
aralkylglucosinolic acid;
benzenes		00low000000
DPI2
0
benzenes;
morpholines;
secondary carboxamide;
tertiary amino compound;
thiazolidinone		ferroptosis inducer00low000000
l 744832
0
benzenes;
ether;
isopropyl ester;
secondary carboxamide;
sulfone;
thiol		antineoplastic agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
geroprotector		00low000000
glucotropeolin
0
aralkylglucosinolic acid;
benzenes		00low000000
ro 25-6981
0
benzenes;
phenols;
piperidines;
secondary alcohol;
tertiary amino compound		anticonvulsant;
antidepressant;
neuroprotective agent;
NMDA receptor antagonist		00low000000
bm 567
0
benzenes;
sulfonamide		00low000000
varespladib methyl
0
aromatic ether;
benzenes;
indoles;
methyl ester;
primary carboxamide		anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor;
prodrug		00low000000
npi 2358
0
2,5-diketopiperazines;
benzenes;
imidazoles;
olefinic compound		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
microtubule-destabilising agent		00low000000
chlorobactene
0
benzenes;
carotenoid phi-end group;
carotenoid		bacterial metabolite00low000000
ws-5995 c
0
benzenes;
naphthalenes;
ring assembly		00low000000
phevalin
0
benzenes;
pyrazinone		bacterial metabolite;
calpain inhibitor		00low000000
np 031112
0
benzenes;
naphthalenes;
thiadiazolidine		anti-inflammatory agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent		00low000000
ym 216391
0
1,3-oxazoles;
1,3-thiazoles;
azamacrocycle;
benzenes;
heterodetic cyclic peptide		antineoplastic agent;
bacterial metabolite		00low000000
3-(4-nitrophenyl)-N-(4-phenylbutyl)-5-(phenylmethyl)-4,6-dihydro-3aH-pyrrolo[3,4-d]isoxazole-6a-carboxamide
0
benzenes;
organic amino compound		00low000000
SYC-435
0
benzenes;
cyclic hydroxamic acid;
pyridone		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor		00low000000
trelagliptin
0
benzenes;
nitrile		00low000000
1-hydroxy-5-nitro-N-(2-phenylethyl)-4-spiro[benzimidazole-2,1'-cyclohexane]imine
0
benzenes00low000000
5-methyl-5-pentyl-2-phenyl-1,2,4-triazolidine-3-thione
0
benzenes00low000000
N-methyl-3-[5-(3-phenylpropyl)-1,3,4-oxadiazol-2-yl]-N-(3-thiophenylmethyl)propanamide
0
benzenes00low000000
(5S)-1-(4-cyclohexylbutyl)-5-phenyl-4,5-dihydroimidazol-2-amine
0
benzenes00low000000
phenylmercuric acetate
0
arylmercury compound;
benzenes		00low000000
sm 164
0
benzenes;
organic heterobicyclic compound;
secondary carboxamide;
triazoles		antineoplastic agent;
apoptosis inducer;
radiosensitizing agent		00low000000
5-Methyl-1-phenyl-3-hexanyl sulfamate
0
benzenes00low000000
1-(3-methoxyphenyl)-3-(4-phenylbutyl)urea
0
benzenes;
organic amino compound		00low000000
niraparib
0
benzenes;
indazoles;
piperidines;
primary carboxamide		antineoplastic agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor		00low000000
n-alpha-benzoyl-n5-(2-chloro-1-iminoethyl)-l-ornithine amide
0
benzenes00low000000
1,1,1,2,2-pentafluoro-7-phenylheptan-3-one
0
benzenes00low000000
3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline
0
benzenes;
sulfonamide		00low000000
difenacoum
0
benzenes;
naphthalenes;
ring assembly		00low000000
warfarin
0
benzenes;
hydroxycoumarin;
methyl ketone		00low000000
bromfenacoum
0
benzenes;
naphthalenes;
ring assembly		00low000000
flocoumafen
0
benzenes;
naphthalenes;
ring assembly		00low000000
gsk2879552
0
benzenes;
benzoic acids;
cyclopropanes;
monocarboxylic acid;
piperidines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor		00low000000
quinacrine
0
acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor		00low000000
vanilmandelic acid
0
2-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite00low000000
4-(2,4-dichlorophenoxy)butyric acid
0
aromatic ether;
monocarboxylic acid;
organochlorine compound		agrochemical;
phenoxy herbicide;
synthetic auxin		00low000000
win 52035
0
aromatic ether00low000000
win 52084
0
aromatic ether00low000000
5-(nonyloxy)tryptamine
0
aromatic ether;
primary amino compound;
tryptamines		serotonergic agonist00low000000
methylbufotenin
0
aromatic ether;
tertiary amino compound;
tryptamine alkaloid		hallucinogen;
plant metabolite		00low000000
5-methoxytryptamine
0
aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist		00low000000
ro 48-8071
0
aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound		antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor		00low000000
rtki cpd
0
aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector		00low000000
amsacrine
0
acridines;
aromatic ether;
sulfonamide		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor		00low000000
aristolochic acid i
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one
0
aromatic ether;
benzoxazine;
cyclic hydroxamic acid;
lactol		allelochemical;
plant metabolite		00low000000
bufetolol
0
aromatic ether00low000000
bufexamac
0
aromatic ether;
hydroxamic acid		antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
bunitrolol
0
aromatic ether00low000000
bupranolol
0
aromatic ether00low000000
verapamil
0
aromatic ether;
nitrile;
polyether;
tertiary amino compound		00low000000
cgp 12177
0
aromatic ether;
benzimidazoles;
secondary alcohol;
secondary amino compound		beta-adrenergic antagonist00low000000
ciglitazone
0
aromatic ether;
thiazolidinone		antineoplastic agent;
insulin-sensitizing drug		00low000000
cirazoline
0
aromatic ether00low000000
clofibrate
0
aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist		00low000000
clofibric acid
0
aromatic ether;
monocarboxylic acid;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist		00low000000
colchicine, (+-)-isomer
0
acetamides;
alkaloid;
aromatic ether;
carbotricyclic compound		microtubule-destabilising agent;
plant metabolite		00low000000
croconazole
0
aromatic ether;
conazole antifungal drug;
imidazole antifungal drug;
monochlorobenzenes		00low000000
cypermethrin
0
aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound		agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide		00low000000
racemethorphan
0
aromatic ether;
morphinane alkaloid;
morphinane-like compound;
organic heterotetracyclic compound		00low000000
dibucaine
0
aromatic ether;
monocarboxylic acid amide;
tertiary amino compound		topical anaesthetic00low000000
dilacor xr
0
acetate ester;
aromatic ether;
benzothiazepine;
lactam;
tertiary amino compound		00low000000
domiphen
0
aromatic ether00low000000
donepezil
0
aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent		00low000000
epirizole
0
aromatic ether00low000000
ethacrynic acid
0
aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic		00low000000
ethoxyquin
0
aromatic ether;
quinolines		antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator		00low000000
ethoxzolamide
0
aromatic ether;
benzothiazoles;
sulfonamide		antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor		00low000000
2-hexyloxybenzamide
0
aromatic ether;
benzamides		antifungal agent00low000000
carbonyl cyanide p-trifluoromethoxyphenylhydrazone
0
aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore		00low000000
fenofibrate
0
aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
fenvalerate
0
aromatic ether;
carboxylic ester;
monochlorobenzenes		pyrethroid ester acaricide;
pyrethroid ester insecticide		00low000000
flecainide
0
aromatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines		anti-arrhythmia drug00low000000
fluoxetine
0
(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound		00low000000
gallamine triethiodide
0
aromatic ether00low000000
gemfibrozil
0
aromatic etherantilipemic drug00low000000
haloprogin
0
aromatic ether00low000000
indomethacin
0
aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic		00low000000
ipriflavone
0
aromatic ether;
isoflavones		bone density conservation agent00low000000
ly 171883
0
acetophenones;
aromatic ether;
phenols;
tetrazoles		anti-asthmatic drug;
leukotriene antagonist		00low000000
mephenesin
0
aromatic ether;
glycerol ether		00low000000
methocarbamol
0
aromatic ether;
carbamate ester;
secondary alcohol		00low000000
methoctramine
0
aromatic ether;
tetramine		muscarinic antagonist00low000000
methoxsalen
0
aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite		00low000000
metoprolol
0
aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
mexiletine
0
aromatic ether;
primary amino compound		anti-arrhythmia drug00low000000
midodrine
0
amino acid amide;
aromatic ether;
secondary alcohol		alpha-adrenergic agonist;
prodrug;
sympathomimetic agent;
vasoconstrictor agent		00low000000
clorgyline
0
aromatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound		antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor		00low000000
nefazodone
0
aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles		alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor		00low000000
nimesulide
0
aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug		00low000000
nisoxetine
0
aromatic ether;
secondary amino compound		adrenergic uptake inhibitor;
antidepressant		00low000000
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
0
aromatic ether;
C-nitro compound;
sulfonamide		antineoplastic agent;
cyclooxygenase 2 inhibitor		00low000000
omeprazole
0
aromatic ether;
benzimidazoles;
pyridines;
sulfoxide		00low000000
oxprenolol
0
aromatic ether00low000000
pantoprazole
0
aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic		00low000000
pd 153035
0
aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist		00low000000
pentamidine
0
aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic		00low000000
phenacetin
0
acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug		00low000000
pioglitazone
0
aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic		00low000000
piretanide
0
aromatic ether00low000000
pramoxine
0
aromatic ether;
morpholines		local anaesthetic00low000000
prazosin
0
aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor		00low000000
primaquine
0
aminoquinoline;
aromatic ether;
N-substituted diamine		antimalarial00low000000
proglumetacin
0
aromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug		00low000000
propoxur
0
aromatic ether;
carbamate ester		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
pyrilamine
0
aromatic ether;
ethylenediamine derivative		H1-receptor antagonist00low000000
sulfadimethoxine
0
aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic		00low000000
tetrahydropapaverine
0
aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
polyether;
secondary amino compound		00low000000
tilorone
0
aromatic ether;
diether;
fluoren-9-ones;
tertiary amino compound		anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist		00low000000
ultram
0
aromatic ether;
tertiary alcohol;
tertiary amino compound		00low000000
triclosan
0
aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic		00low000000
viloxazine
0
aromatic ether00low000000
wb 4101
0
aromatic ether;
benzodioxine;
secondary amino compound		alpha-adrenergic antagonist00low000000
3,3',5-triiodothyropropionic acid
0
aromatic ether00low000000
methacetin
0
acetamides;
aromatic ether		00low000000
mestranol
0
17beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound		prodrug;
xenoestrogen		00low000000
visnagin
0
aromatic ether;
furanochromone;
polyketide		anti-inflammatory agent;
antihypertensive agent;
EC 1.1.1.37 (malate dehydrogenase) inhibitor;
phytotoxin;
plant metabolite;
vasodilator agent		00low000000
2-tert-butyl-4-hydroxyanisole
0
aromatic ether;
phenols		00low000000
mecoprop
0
aromatic ether;
monocarboxylic acid;
monochlorobenzenes		00low000000
phenetidine
0
aromatic ether;
substituted aniline		00low000000
2-methyl-4-chlorophenoxy gamma-butyric acid
0
aromatic ether;
monocarboxylic acid;
monochlorobenzenes		environmental contaminant;
phenoxy herbicide;
xenobiotic		00low000000
4-bromophenyl phenyl ether
0
aromatic ether;
organobromine compound		00low000000
di-(4-aminophenyl)ether
0
aromatic ether00low000000
phenyl ether
0
aromatic etherplant metabolite00low000000
diglycidyl resorcinol ether
0
aromatic ether00low000000
phenetole
0
aromatic ether00low000000
scoparone
0
aromatic ether;
coumarins		anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite		00low000000
dimethoxyphenylethylamine
0
alkaloid;
aromatic ether;
phenylethylamine		allergen;
plant metabolite		00low000000
dichlorprop
0
aromatic ether;
dichlorobenzene;
monocarboxylic acid		00low000000
3-tert-butyl-4-hydroxyanisole
0
aromatic ether;
phenols		antioxidant;
human xenobiotic metabolite		00low000000
ethyl vanillin
0
aromatic ether;
benzaldehydes;
phenols		antioxidant;
flavouring agent		00low000000
benzethonium chloride
0
aromatic ether;
chloride salt;
quaternary ammonium salt		antibacterial agent;
antifungal agent;
antiseptic drug;
antiviral agent;
disinfectant		00low000000
peucedanin
0
aromatic ether;
furanocoumarin;
lactone		plant metabolite00low000000
phenetidine
0
aromatic ether;
primary amino compound;
substituted aniline		drug metabolite00low000000
6-methoxybenzoxazolinone
0
aromatic ether;
benzoxazole		antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite		00low000000
3-anisidine
0
aromatic ether;
substituted aniline		00low000000
domiphen bromide
0
aromatic ether00low000000
dibrompropamidine
0
aromatic ether00low000000
4-Ethoxyphenol
0
aromatic ether;
phenols		00low000000
bulbocapnine
0
aporphine alkaloid;
aromatic ether;
oxacycle;
phenols		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
EC 1.4.3.22 (diamine oxidase) inhibitor;
plant metabolite		00low000000
benzydamine
0
aromatic ether;
indazoles;
tertiary amino compound		analgesic;
central nervous system stimulant;
hallucinogen;
local anaesthetic;
non-steroidal anti-inflammatory drug		00low000000
xylocholine
0
aromatic ether00low000000
3-methoxycatechol
0
aromatic ether;
catechols		G-protein-coupled receptor agonist00low000000
2-phenoxypropanoic acid
0
aromatic ether;
carboxylic acid		00low000000
6-methoxyquinoline
0
aromatic ether;
quinolines		00low000000
metaxalone
0
aromatic ether00low000000
heliamine
0
aromatic ether;
diether;
isoquinoline alkaloid;
isoquinolines		plant metabolite00low000000
2,4,6-trichlorophenyl 4-nitrophenyl ether
0
aromatic ether;
C-nitro compound;
chlorobenzenes		EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide		00low000000
etridiazol
0
aromatic ether;
organochlorine compound;
thiadiazole antifungal agent;
thiadiazoles		antifungal agrochemical;
nitrification inhibitor		00low000000
toliprolol
0
aromatic ether00low000000
5-methoxyindoleacetic acid
0
aromatic ether;
indole-3-acetic acids		antibacterial agent;
Brassica napus metabolite;
carcinogenic agent;
human urinary metabolite;
marine xenobiotic metabolite;
rat metabolite		00low000000
iproclozide
0
aromatic ether00low000000
phenoxyacetic acid
0
aromatic ether;
monocarboxylic acid		allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant		00low000000
nafenopin
0
aromatic ether;
monocarboxylic acid		00low000000
methyl vanillate
0
aromatic ether;
benzoate ester;
phenols		antioxidant;
plant metabolite		00low000000
5-methoxyindole-2-carboxylic acid
0
aromatic ether;
indolecarboxylic acid		EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor;
hypoglycemic agent;
plant metabolite		00low000000
2-isopropoxyphenol
0
aromatic ether;
phenols		00low000000
dehydroemetine
0
aromatic ether;
isoquinolines;
pyridoisoquinoline		antileishmanial agent;
antimalarial;
antiprotozoal drug		00low000000
1,2-epoxy-3-(p-nitrophenoxy)propane
0
aromatic ether;
C-nitro compound;
epoxide		00low000000
laurolitsine
0
aporphine alkaloid;
aromatic ether;
phenols		HIV-1 integrase inhibitor;
metabolite		00low000000
metocurine iodide
0
aromatic ether00low000000
ac 45594
0
aromatic ether00low000000
3-phenoxybenzylalcohol
0
aromatic ether;
benzyl alcohols		marine xenobiotic metabolite00low000000
devrinol
0
aromatic ether;
monocarboxylic acid amide;
naphthalenes		00low000000
fluorodifen
0
aromatic ether00low000000
acridine half-mustard
0
aminoacridines;
aromatic ether;
organochlorine compound;
secondary amino compound		mutagen00low000000
precocene i
0
aromatic ether;
chromenes		plant metabolite;
precocenes		00low000000
oxadiazon
0
aromatic ether00low000000
lofexidine
0
aromatic ether;
carboxamidine;
dichlorobenzene;
imidazoles		alpha-adrenergic agonist;
antihypertensive agent		00low000000
alclofenac
0
aromatic ether;
monocarboxylic acid;
monochlorobenzenes		drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
phenylglycidyl ether
0
aromatic ether00low000000
phenoxyethanol
0
aromatic ether;
glycol ether;
primary alcohol		antiinfective agent;
central nervous system depressant		00low000000
metipranolol
0
acetate ester;
aromatic ether;
propanolamine;
secondary amino compound		anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist		00low000000
silybin
0
aromatic ether;
benzodioxine;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone		antineoplastic agent;
antioxidant;
hepatoprotective agent;
plant metabolite		00low000000
oxamethacin
0
aromatic ether;
hydroxamic acid;
N-acylindole;
organochlorine compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
canadine
0
aromatic ether;
berberine alkaloid;
organic heteropentacyclic compound;
oxacycle		00low000000
7-ethoxycoumarin
0
aromatic ether;
coumarins		00low000000
medifoxamine
0
aromatic ether00low000000
chlormethoxynil
0
aromatic ether00low000000
climbazole
0
aromatic ether;
hemiaminal ether;
imidazoles;
ketone;
monochlorobenzenes		00low000000
4-hexyloxyaniline
0
aromatic ether;
substituted aniline		00low000000
ticrynafen
0
aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic		00low000000
2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid
0
aromatic ether;
dichlorobenzene;
diether;
monocarboxylic acid		00low000000
bezafibrate
0
aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
oxyfluorofen
0
aromatic etherEC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide		00low000000
triadimefon
0
aromatic ether;
hemiaminal ether;
ketone;
monochlorobenzenes;
triazoles		00low000000
levobunolol
0
aromatic ether;
cyclic ketone;
propanolamine		antiglaucoma drug;
beta-adrenergic antagonist		00low000000
dichlorfop-methyl
0
aromatic ether;
dichlorobenzene;
diether;
methyl ester		00low000000
decamethrin
0
aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound		agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide		00low000000
triadimenol
0
aromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite		00low000000
triclopyr
0
aromatic ether;
chloropyridine;
monocarboxylic acid		agrochemical;
environmental contaminant;
herbicide;
xenobiotic		00low000000
prenalterol
0
aromatic ether00low000000
st 1059
0
aromatic ether;
primary amino compound;
secondary alcohol		alpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent		00low000000
paroxetine
0
aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines		antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor		00low000000
acifluorfen
0
aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide		00low000000
bopindolol
0
aromatic ether;
benzoate ester;
methylindole;
secondary amino compound		00low000000
fenpropathrin, (+-)-isomer
0
aromatic ether;
cyclopropanecarboxylate ester		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide		00low000000
triflumuron
0
aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound		00low000000
flutolanil
0
(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
benzanilide fungicide		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor		00low000000
fenoxaprop ethyl
0
aromatic ether00low000000
triclabendazole
0
aromatic ether00low000000
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid
0
aminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		environmental contaminant;
herbicide;
xenobiotic		00low000000
fluvalinate
0
(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide		00low000000
haloxyfop
0
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines		00low000000
fluazifop-butyl
0
aromatic ether;
carboxylic ester;
organofluorine compound;
pyridines		00low000000
fomesafen
0
aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide		00low000000
fenoxycarb
0
aromatic ether;
carbamate ester		environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic		00low000000
quizalofop-ethyl
0
aromatic ether;
ethyl ester;
organochlorine compound;
quinoxaline derivative		00low000000
cetamolol
0
aromatic ether00low000000
atomoxetine
0
aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic		00low000000
methyl bensulfuron
0
aromatic ether;
methyl ester;
N-sulfonylurea;
pyrimidines		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide		00low000000
itraconazole
0
aromatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles		EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor		00low000000
loxtidine
0
aromatic ether;
piperidines;
primary alcohol;
triazoles		H2-receptor antagonist00low000000
disoxaril
0
aromatic ether00low000000
chlorimuron ethyl
0
aromatic ether;
ethyl ester;
N-sulfonylurea;
organochlorine pesticide;
pyrimidines;
sulfamoylbenzoate		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide		00low000000
tepoxalin
0
aromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles		antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
esmolol
0
aromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound		00low000000
pioglitazone hydrochloride
0
aromatic ether00low000000
aripiprazole
0
aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone		drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist		00low000000
sulfametrole
0
aromatic ether;
substituted aniline;
sulfonamide antibiotic;
thiadiazoles		00low000000
propamidine
0
aromatic ether;
guanidines;
polyether		antimicrobial agent;
antiseptic drug		00low000000
hexamidine
0
aromatic ether;
guanidines;
polyether		antimicrobial agent;
antiseptic drug		00low000000
o-4-methylthymine
0
aromatic ether;
methylthymine		human metabolite00low000000
fenclofenac
0
aromatic ether00low000000
tetraiodothyroacetic acid
0
2-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid		apoptosis inducer;
human metabolite;
thyroid hormone		00low000000
fluazuron
0
aromatic ether;
chloropyridine;
monochlorobenzenes;
N-acylurea;
organochlorine acaricide;
organofluorine acaricide;
phenylureas		acaricide;
mite growth regulator		00low000000
etiroxate
0
aromatic ether00low000000
etofamide
0
aromatic ether00low000000
d 888
0
aromatic ether;
nitrile;
tertiary amino compound		anti-arrhythmia drug;
calcium channel blocker;
vasodilator agent		00low000000
esreboxetine
0
aromatic ether00low000000
guaethol
0
aromatic ether;
phenols;
volatile organic compound		flavouring agent00low000000
spiramide
0
aromatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
serotonergic antagonist		00low000000
5'-nitro-2'-propoxyacetanilide
0
aromatic ether;
C-nitro compound		00low000000
suberosin
0
aromatic ether;
coumarins		anticoagulant;
plant metabolite		00low000000
4-methoxyestradiol
0
17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols		estrogen;
human metabolite;
rat metabolite		00low000000
toltrazuril
0
aromatic ether00low000000
plafibride
0
aromatic ether00low000000
cinitapride
0
aromatic ether;
C-nitro compound		00low000000
isoscopoletin
0
aromatic ether;
hydroxycoumarin		plant metabolite00low000000
ethofenprox
0
aromatic etherpyrethroid ether insecticide00low000000
uk 68798
0
aromatic ether;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
potassium channel blocker		00low000000
hp 873
0
1,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist		00low000000
fenoxypropazine
0
aromatic ether00low000000
fluphenacur
0
aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound		00low000000
amezinium
0
aromatic ether;
primary arylamine;
pyridazinium ion		adrenergic uptake inhibitor;
antihypotensive agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
sympathomimetic agent		00low000000
rubrofusarin
0
aromatic ether;
benzochromenone;
phenols;
polyketide		biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
fungal metabolite		00low000000
triasulfuron
0
1,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound		agrochemical;
herbicide		00low000000
dauricine
0
aromatic ether;
bisbenzylisoquinoline alkaloid;
isoquinolines;
phenols;
tertiary amino compound		plant metabolite00low000000
uvaretin
0
aromatic ether;
dihydrochalcones;
polyketide;
resorcinol		antineoplastic agent;
plant metabolite		00low000000
fangchinoline
0
aromatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle		anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite		00low000000
prochloraz
0
amide fungicide;
aromatic ether;
conazole fungicide;
imidazole fungicide;
imidazoles;
trichlorobenzene;
ureas		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic		00low000000
stictic acid
0
aromatic ether00low000000
pramoxine hydrochloride
0
aromatic ether00low000000
4-methoxybenzylamine
0
aralkylamino compound;
aromatic ether;
primary amino compound		00low000000
xanthurenic acid 8-methyl ether
0
aromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid		carcinogenic agent;
metabolite;
mouse metabolite		00low000000
adriamycinol
0
aminoglycoside;
anthracycline antibiotic;
aromatic ether;
deoxy hexoside;
p-quinones;
phenols;
polyol;
tetracenequinones		cardiotoxic agent;
drug metabolite		00low000000
difenoconazole
0
aromatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic		00low000000
a 8947
0
aromatic ether;
biaryl;
N-sulfonylurea;
pyrazole pesticide;
tetrazoles		EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide		00low000000
thifluzamide
0
1,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor		00low000000
ethylhydrocupreine
0
aromatic ether;
cinchona alkaloid		EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor00low000000
7,8-dihydromethysticin
0
2-pyranones;
aromatic ether		00low000000
4,5-dimethoxy-2-nitrobenzaldehyde
0
aromatic ether;
C-nitro compound		00low000000
bisphenol f diglycidyl ether
0
aromatic ether;
diarylmethane;
epoxide		00low000000
oryzemate
0
1,2-benzisothiazole;
aromatic ether;
benzothiazole fungicide;
sulfone		antifungal agrochemical;
plant activator		00low000000
bitertanol
0
aromatic ether;
biphenyls;
secondary alcohol;
triazoles		00low000000
fluazifop
0
aromatic ether;
monocarboxylic acid;
organofluorine compound;
pyridines		00low000000
diflufenican
0
(trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic		00low000000
hexafluoron
0
aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organochlorine insecticide;
organofluorine insecticide		00low000000
diethofencarb
0
aromatic ether;
carbamate ester;
carbanilate fungicide		antifungal agrochemical00low000000
pyriproxyfen
0
aromatic ether;
pyridines		juvenile hormone mimic00low000000
methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate
0
aromatic ether;
benzoate ester;
diamino-1,3,5-triazine;
methyl ester;
N-sulfonylurea		EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide		00low000000
dpx e9636
0
aromatic ether;
N-sulfonylurea;
pyridines;
pyrimidines;
sulfone		environmental contaminant;
herbicide;
xenobiotic		00low000000
aclonifen
0
aromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide		00low000000
cinosulfuron
0
aromatic ether00low000000
clodinafop-propargyl
0
aromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines		agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide		00low000000
triflusulfuron-methyl
0
1,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide		00low000000
vestitol
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		anti-inflammatory agent;
phytoalexin;
plant metabolite		00low000000
laudanine
0
aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
phenols;
racemate		00low000000
cryptopleurine
0
alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound		antineoplastic agent;
antiviral agent;
protein synthesis inhibitor		00low000000
6-hydroxymethylmexiletine
0
aromatic ether00low000000
4-hydroxymexiletine
0
aromatic ether;
phenols		00low000000
cloquintocet-mexyl
0
aromatic ether;
carboxylic ester;
organochlorine compound;
quinolines		00low000000
novaluron
0
aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound		00low000000
bursehernin
0
aromatic ether;
benzodioxoles;
butan-4-olide;
lignan		plant metabolite00low000000
2,2',4,4'-tetrabromodiphenyl ether
0
aromatic ether;
organobromine compound		00low000000
allocryptopine
0
aromatic ether;
cyclic acetal;
cyclic ketone;
dibenzazecine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		00low000000
sporidesmin
0
aromatic ether;
cyclic ketone;
diketone;
organic disulfide;
organic heteropentacyclic compound;
organochlorine compound;
secondary alcohol;
tertiary alcohol;
tertiary amino compound		mycotoxin;
Wnt signalling activator		00low000000
syringaresinol
0
aromatic ether;
furofuran;
lignan;
polyether;
polyphenol		plant metabolite00low000000
p-methoxy-n-methylphenethylamine
0
aromatic ether;
secondary amino compound		metabolite00low000000
aflatoxin q1
0
aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human xenobiotic metabolite		00low000000
u 73122
0
aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor00low000000
cyfluthrin
0
aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester insecticide		00low000000
norverapamil
0
aromatic ether;
nitrile;
polyether;
secondary amino compound		00low000000
fumitremorgin a
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		mycotoxin00low000000
deguelin
0
aromatic ether;
diether;
organic heteropentacyclic compound;
rotenones		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor;
plant metabolite		00low000000
aristolochic acid ii
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
tephrosin
0
aromatic ether;
cyclic ketone;
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
pesticide		00low000000
alpha-hydroxymetoprolol
0
aromatic ether00low000000
5-(tetradecyloxy)-2-furancarboxylic acid
0
aromatic ether;
furoic acid		antineoplastic agent;
apoptosis inducer;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
PPARalpha agonist		00low000000
tafenoquine
0
(trifluoromethyl)benzenes;
aminoquinoline;
aromatic ether;
primary amino compound;
secondary amino compound		00low000000
5-hydroxymethylomeprazole
0
aromatic ether;
benzimidazoles;
pyridines;
sulfoxide		drug metabolite00low000000
mosapride
0
aromatic ether;
benzamides;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
secondary carboxamide;
substituted aniline;
tertiary amino compound		00low000000
ym 12617
0
aromatic ether;
secondary amino compound;
sulfonamide		00low000000
gefitinib
0
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist		00low000000
cgp 28392
0
aromatic ether00low000000
sodium-binding benzofuran isophthalate
0
1-benzofurans;
aromatic ether;
crown compound;
tetracarboxylic acid		fluorochrome00low000000
garenoxacin
0
aromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
non-steroidal anti-inflammatory drug		00low000000
ay 25545
0
acetate ester;
aromatic ether;
C-glycosyl compound;
naphthoisochromene;
olefinic compound;
phenols;
tertiary amine		antimicrobial agent;
antineoplastic agent;
bacterial metabolite		00low000000
reboxetine
0
aromatic ether00low000000
b 823-08
0
aromatic ether00low000000
cyclazosin
0
aromatic amide;
aromatic ether;
furans;
monocarboxylic acid amide;
quinazolines;
quinoxaline derivative		adenosine A2A receptor antagonist00low000000
ivabradine
0
aromatic ether;
benzazepine;
carbobicyclic compound;
tertiary amino compound		cardiotonic drug00low000000
febuxostat
0
1,3-thiazolemonocarboxylic acid;
aromatic ether;
nitrile		EC 1.17.3.2 (xanthine oxidase) inhibitor00low000000
marsupsin
0
1-benzofurans;
aromatic ether;
polyphenol		antilipemic drug;
hypoglycemic agent;
metabolite		00low000000
6,6'-bieckol
0
aromatic ether;
oxacycle;
phlorotannin		anti-HIV-1 agent;
metabolite;
radical scavenger		00low000000
xibenolol
0
aromatic ether00low000000
cicloprolol
0
aromatic ether00low000000
chs 828
0
aromatic ether00low000000
2-(4-methoxyphenoxy)propanoic acid
0
aromatic ether;
carboxylic acid		00low000000
moxifloxacin
0
aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug00low000000
rp 73401
0
aromatic ether;
benzamides;
chloropyridine;
monocarboxylic acid amide		anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
phosphodiesterase IV inhibitor		00low000000
2,2',4,4',5,5'-hexabrominated diphenyl ether
0
aromatic ether;
organobromine compound		00low000000
birb 796
0
aromatic ether;
morpholines;
naphthalenes;
pyrazoles;
ureas		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
immunomodulator		00low000000
schizandrin b
0
aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin		anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite		00low000000
s 23121
0
aromatic ether;
dicarboximide;
monochlorobenzenes;
monofluorobenzenes;
pyrroline;
terminal acetylenic compound		00low000000
acrovestone
0
acetophenones;
aromatic ether;
olefinic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		00low000000
corytuberine
0
aporphine alkaloid;
aromatic ether;
organic heterotetracyclic compound;
polyphenol;
tertiary amino compound		plant metabolite00low000000
actinodaphine
0
aporphine alkaloid;
aromatic ether;
organic heteropentacyclic compound;
phenols;
secondary amino compound		antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite;
platelet aggregation inhibitor;
topoisomerase inhibitor		00low000000
isohomovanillic acid
0
aromatic ether;
phenols;
phenylacetic acids		metabolite00low000000
3,5-diiodothyropropionic acid
0
aromatic ether;
monocarboxylic acid;
organoiodine compound;
phenols		00low000000
7,8-dihydro-5,6-dehydrokawain
0
2-pyranones;
aromatic ether		00low000000
4-amino-2-methoxypyrimidine
0
aminopyrimidine;
aromatic ether;
methylcytosine		metabolite00low000000
aristolochic acid D
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
nephrotoxin;
toxin		00low000000
myricanone
0
aromatic ether;
cyclic ketone;
diarylheptanoid;
methoxybenzenes;
phenols		antineoplastic agent;
plant metabolite		00low000000
pannarin
0
aldehyde;
aromatic ether;
depsidones;
organic heterotricyclic compound;
organochlorine compound;
phenols		antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lichen metabolite		00low000000
aminopotentidine
0
aromatic ether;
benzamides;
guanidines;
nitrile;
piperidines;
substituted aniline		H2-receptor antagonist00low000000
aristolochic acid c
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
pluviatolide
0
aromatic ether;
benzodioxoles;
butan-4-olide;
lignan;
phenols		plant metabolite00low000000
erysodine
0
aromatic ether;
diether;
Erythrina alkaloid;
organic heterotetracyclic compound;
phenols		antiparasitic agent;
nicotinic antagonist;
phytogenic insecticide		00low000000
erlotinib
0
aromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound		antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor		00low000000
rubrofusarin B
0
aromatic ether;
benzochromenone;
naphtho-gamma-pyrone;
phenols;
polyketide		Aspergillus metabolite00low000000
ly 293111
0
aromatic ether00low000000
enrasentan
0
aromatic ether;
benzodioxoles;
indanes;
monocarboxylic acid;
monomethoxybenzene;
primary alcohol		antihypertensive agent;
endothelin receptor antagonist		00low000000
quizalofop
0
aromatic ether;
monocarboxylic acid;
organochlorine compound;
quinoxaline derivative		00low000000
cyhalofop-butyl
0
aromatic ether00low000000
cyperin
0
aromatic ether00low000000
aflatoxin b1
0
aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite		00low000000
etravirine
0
aminopyrimidine;
aromatic ether;
dinitrile;
organobromine compound		antiviral agent;
HIV-1 reverse transcriptase inhibitor		00low000000
5-o-methyllicoricidin
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		antibacterial agent;
plant metabolite		00low000000
pronuciferine
0
aromatic ether;
cyclic ketone;
isoquinoline alkaloid;
isoquinolines;
organic heterotetracyclic compound		plant metabolite00low000000
dronedarone
0
1-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic		00low000000
famoxadone
0
aromatic ether;
carbohydrazide;
oxazolidinone		00low000000
cimicoxib
0
aromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug		00low000000
sorafenib
0
(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide		angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor		00low000000
dabuzalgron
0
aromatic ether;
imidazoles;
monochlorobenzenes;
sulfonamide		alpha-adrenergic agonist00low000000
fonsecin
0
aromatic ether;
cyclic hemiketal;
heptaketide;
naphtho-gamma-pyrone;
phenols		Aspergillus metabolite;
marine metabolite		00low000000
lasofoxifene
0
aromatic ether;
N-alkylpyrrolidine;
naphthols;
tetralins		antineoplastic agent;
bone density conservation agent;
cardioprotective agent;
estrogen receptor agonist;
estrogen receptor antagonist		00low000000
(+-)-Dihydromethysticin
0
2-pyranones;
aromatic ether		00low000000
2-[2-[2-(2-aminophenoxy)ethoxy]ethoxy]aniline
0
aromatic ether;
substituted aniline		00low000000
chondocurine (1beta)-(+-)-isomer
0
aromatic ether00low000000
1-methyl-4-prop-2-enoxy-2-pyrimidinone
0
aromatic ether;
pyrimidone		00low000000
noscapine
0
aromatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound		antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite		00low000000
4-[4-(3-methyl-4-nitrophenoxy)butoxy]benzonitrile
0
aromatic ether;
C-nitro compound		00low000000
lariciresinol
0
aromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol		antifungal agent;
plant metabolite		00low000000
tryptoquivaline
0
aromatic ether;
indole alkaloid;
organic heteropentacyclic compound		breast cancer resistance protein inhibitor;
mycotoxin		00low000000
2-methoxyestrone
0
17-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols		human metabolite;
mouse metabolite		00low000000
win 54954
0
aromatic ether00low000000
silychristin
0
1-benzofurans;
aromatic ether;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone		lipoxygenase inhibitor;
metabolite;
prostaglandin antagonist;
radical scavenger		00low000000
cleomiscosin a
0
aromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol		anti-inflammatory agent;
metabolite		00low000000
bispyribac
0
aromatic ether;
benzoic acids;
monocarboxylic acid;
pyrimidines		herbicide00low000000
petunidin-3-glucoside
0
anthocyanin cation;
aromatic ether;
beta-D-glucoside		antioxidant;
metabolite		00low000000
malvidin-3-glucoside
0
anthocyanin cation;
aromatic ether;
beta-D-glucoside		metabolite00low000000
dioncophylline c
0
aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthols		antimalarial;
antiplasmodial drug;
metabolite		00low000000
stigmatellin
0
aromatic ether;
chromones;
olefinic compound;
phenols		bacterial metabolite;
quinol oxidation site inhibitor		00low000000
roflumilast
0
aromatic ether;
benzamides;
chloropyridine;
cyclopropanes;
organofluorine compound		anti-asthmatic drug;
phosphodiesterase IV inhibitor		00low000000
teniposide
0
aromatic ether;
beta-D-glucoside;
cyclic acetal;
furonaphthodioxole;
gamma-lactone;
monosaccharide derivative;
phenols;
thiophenes		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor		00low000000
prinomastat
0
aromatic ether;
hydroxamic acid;
pyridines;
sulfonamide;
thiomorpholines		antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
matrix metalloproteinase inhibitor		00low000000
posaconazole
0
aromatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles		trypanocidal drug00low000000
gancaonin I
0
1-benzofurans;
aromatic ether;
resorcinols		antibacterial agent;
plant metabolite		00low000000
glycyrin
0
aromatic ether;
coumarins;
hydroxyisoflavans		antibacterial agent;
metabolite;
plant metabolite		00low000000
glyasperin D
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		plant metabolite00low000000
licoricidin
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		antibacterial agent;
plant metabolite		00low000000
egonol
0
1-benzofurans;
aromatic ether;
benzodioxoles;
primary alcohol		plant metabolite00low000000
N-ethylharmine
0
aromatic ether;
beta-carbolines;
semisynthetic derivative		anti-HIV agent00low000000
pf 1163a
0
aromatic ether;
lactam;
macrolide antibiotic;
secondary alcohol		antifungal agent;
Penicillium metabolite		00low000000
pf 1163b
0
aromatic ether;
lactam;
macrolide antibiotic		antifungal agent;
Penicillium metabolite		00low000000
licocoumarone
0
1-benzofurans;
aromatic ether;
resorcinols		antibacterial agent;
apoptosis inducer;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite		00low000000
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide
0
aromatic ether00low000000
LSM-22807
0
aromatic ether00low000000
N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide
0
aromatic ether00low000000
piperlactam s
0
alkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols		anti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-one
0
aromatic ether00low000000
antofine
0
alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound		angiogenesis inhibitor;
anti-inflammatory agent;
antimicrobial agent;
antineoplastic agent;
antiviral agent;
phytotoxin;
plant metabolite		00low000000
xanthohumol
0
aromatic ether;
chalcones;
polyphenol		anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite		00low000000
2-phenoxy-N-(2-pyridinyl)butanamide
0
aromatic ether00low000000
6-amino-4-(2-ethoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
aromatic ether;
pyranopyrazole		00low000000
N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamide
0
aromatic ether00low000000
2-(3,4-diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazole
0
aromatic ether00low000000
2-[[5-(phenoxymethyl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetamide
0
aromatic ether00low000000
1-(8-methyl-2,5,11,14-tetraoxa-8-azabicyclo[13.4.0]nonadeca-1(15),16,18-trien-17-yl)ethanol
0
aromatic ether00low000000
3-[2-(3-phenoxypropyl)-5-tetrazolyl]pyridine
0
aromatic ether00low000000
1-cyclohexyl-5-(2-phenoxyethylthio)tetrazole
0
aromatic ether00low000000
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamide
0
aromatic ether00low000000
6-amino-4-[3-ethoxy-4-[2-(4-morpholinyl)ethoxy]phenyl]-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
aromatic ether;
pyranopyrazole		00low000000
2-[[5-[(2,3-dimethylphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-1-thiophen-2-ylethanone
0
aromatic ether00low000000
(1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanol
0
aromatic ether00low000000
5-(3-butoxyphenyl)-1,3,4-thiadiazol-2-amine
0
aromatic ether00low000000
3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazole
0
aromatic ether00low000000
6-(3,4,5-triethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
0
aromatic ether;
triazolothiadiazole		00low000000
4-(1-benzotriazolyl)-5-(2-methoxyphenoxy)benzene-1,2-dicarbonitrile
0
aromatic ether00low000000
4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thione
0
aromatic ether00low000000
7-ethoxy-9-nitro-5H-benzo[b][1,4]benzoxazepin-6-one
0
aromatic ether00low000000
4-[4-(2-quinoxalinyl)phenoxy]benzene-1,2-dicarbonitrile
0
aromatic ether00low000000
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(phenoxymethyl)-4-triazolecarboxylic acid ethyl ester
0
aromatic ether00low000000
2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide
0
aromatic ether00low000000
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide
0
aromatic ether00low000000
5-[(4-ethylphenoxy)methyl]-N-(2-pyridinylmethyl)-2-furancarboxamide
0
aromatic ether00low000000
7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethione
0
aromatic ether00low000000
N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl ester
0
aromatic ether00low000000
2-(2-bromo-4-methylphenoxy)-N-(2-pyridinylmethyl)acetamide
0
aromatic ether00low000000
1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazine
0
aromatic ether00low000000
2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol
0
aromatic ether;
C-nitro compound		00low000000
4-[[4-(ethylamino)-6-(methylthio)-1,3,5-triazin-2-yl]oxy]benzoic acid ethyl ester
0
aromatic ether00low000000
5-ethyl-3-[[4-(2-methylpropoxy)phenyl]methylthio]-1H-1,2,4-triazole
0
aromatic ether00low000000
[4-[(2-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethione
0
aromatic ether00low000000
5-[(2-chlorophenoxy)methyl]-3-pyridin-4-yl-1,2,4-oxadiazole
0
aromatic ether00low000000
4-(4-phenylmethoxyphenyl)thiadiazole
0
aromatic ether00low000000
N-methyl-2-[[4-methyl-5-[(4-nitrophenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide
0
aromatic ether;
C-nitro compound		00low000000
2-[[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-morpholinyl)ethanone
0
aromatic ether00low000000
4-(3-pyridinyloxy)benzene-1,2-dicarbonitrile
0
aromatic ether00low000000
N-tert-butyl-2-(4-chloro-3-methylphenoxy)acetamide
0
aromatic ether00low000000
1-(2-furanylmethyl)-3-(4-phenoxyphenyl)thiourea
0
aromatic ether00low000000
1-(2-methylpropyl)-3-(4-phenoxyphenyl)thiourea
0
aromatic ether00low000000
1-cyclopentyl-3-(4-phenoxyphenyl)thiourea
0
aromatic ether00low000000
5-[(4-ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamide
0
aromatic ether00low000000
2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide
0
aromatic ether00low000000
5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamide
0
aromatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide
0
aromatic ether00low000000
N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamide
0
aromatic ether00low000000
5-(2-fluorophenoxy)-1-methyl-3-nitro-1,2,4-triazole
0
aromatic ether00low000000
1-methyl-5-(1-naphthalenyloxy)-4-nitroimidazole
0
aromatic ether00low000000
curcumin
0
aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger		00low000000
1-(3,4-dimethoxyphenyl)-3-(2-methoxy-5-nitrophenyl)urea
0
aromatic ether;
C-nitro compound		00low000000
1-cyclopentyl-3-(2-phenoxyphenyl)thiourea
0
aromatic ether00low000000
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamide
0
aromatic ether;
C-nitro compound		00low000000
2-chloro-12-(4-methoxyphenyl)sulfonylquinoxalino[2,3-b][1,4]benzoxazine
0
aromatic ether00low000000
1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)urea
0
aromatic ether;
C-nitro compound		00low000000
2-(2-bromo-4-chlorophenoxy)-N-cyclohexyl-N-methylacetamide
0
aromatic ether00low000000
2-furanyl-[4-(4-phenoxyphenyl)sulfonyl-1-piperazinyl]methanone
0
aromatic ether00low000000
4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamide
0
aromatic ether00low000000
1-(3-chlorophenyl)-3-(2-phenoxyphenyl)thiourea
0
aromatic ether00low000000
N-[3-[2-(1-azepanyl)-4,5-dicyanophenoxy]phenyl]acetamide
0
aromatic ether00low000000
2,5-dimethoxy-N-(4-phenoxyphenyl)benzenesulfonamide
0
aromatic ether00low000000
4-[[4-(dimethylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl ester
0
aromatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide
0
aromatic ether00low000000
1-[4-[[4-(2-chloro-6-nitrophenoxy)phenyl]methoxy]phenyl]ethanone
0
aromatic ether00low000000
N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2,2-dimethylpropanamide
0
aromatic ether00low000000
N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamide
0
aromatic ether00low000000
2-(4-fluorophenoxy)-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)acetamide
0
aromatic ether00low000000
4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-N-propan-2-ylbenzenesulfonamide
0
aromatic ether00low000000
4-(4-tert-butylphenoxy)-5-methoxy-2-phenylpyrimidine
0
aromatic ether00low000000
4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl ester
0
aromatic ether00low000000
Src Inhibitor-1
0
aromatic ether;
polyether;
quinazolines;
secondary amino compound		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor00low000000
N-[2,5-dioxo-6-(4-phenoxyphenyl)-3-pyrano[3,2-c]pyridinyl]benzamide
0
aromatic ether00low000000
2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrile
0
aromatic ether00low000000
6-methyl-5-[2-(2-methylphenoxy)ethyl]-2-sulfanylidene-1H-pyrimidin-4-one
0
aromatic ether00low000000
4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone
0
aromatic ether00low000000
N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diamine
0
aromatic ether00low000000
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thione
0
aromatic ether00low000000
1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thiourea
0
aromatic ether00low000000
N-[3-(3-methylphenoxy)-5-nitrophenyl]-2-(3-nitro-1,2,4-triazol-1-yl)acetamide
0
aromatic ether00low000000
N-bis(2-fluorophenoxy)phosphoryl-3,4-dimethylaniline
0
aromatic ether00low000000
2-[[4-(2-ethoxyanilino)-6-(4-ethoxyanilino)-2-pyrimidinyl]methylidene]propanedinitrile
0
aromatic ether00low000000
5-methyl-3-[(4-pentoxyphenyl)methylthio]-1H-1,2,4-triazole
0
aromatic ether00low000000
4,5-dichloro-1-[2-(4-chlorophenoxy)ethyl]imidazole
0
aromatic ether00low000000
1-butyl-3-(4-phenoxyphenyl)thiourea
0
aromatic ether00low000000
N-(3-cyano-2-thiophenyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]acetamide
0
aromatic ether00low000000
2-(2-bromophenyl)-5-[(2-chlorophenoxy)methyl]-1,3,4-oxadiazole
0
aromatic ether00low000000
5-(4-ethoxyphenyl)-N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-1,3,4-oxadiazol-2-amine
0
aromatic ether00low000000
4-(4-chloro-2-methylphenoxy)-1-(4-morpholinyl)-1-butanone
0
aromatic ether00low000000
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine
0
aromatic ether00low000000
2-[2-(4-chlorophenoxy)ethylthio]pyrimidine
0
aromatic ether00low000000
5-(3-phenoxypropyl)-3-(3-pyridinyl)-1,2,4-oxadiazole
0
aromatic ether00low000000
N-[(3-ethoxy-2-prop-2-enoxyphenyl)methyl]-2-thiazolamine
0
aromatic ether00low000000
2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamide
0
aromatic ether00low000000
4-[2-[(4-chlorophenyl)thio]ethoxy]-3-ethoxybenzaldehyde
0
aromatic ether00low000000
1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester
0
aromatic ether;
C-nitro compound		00low000000
5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thione
0
aromatic ether00low000000
N-tert-butyl-4-(2-fluorophenoxy)-1-butanamine
0
aromatic ether00low000000
N-butyl-4-phenoxy-1-butanamine
0
aromatic ether00low000000
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) ester
0
aromatic ether00low000000
1,3-dimethyl-5-[[2-[2-(4-nitrophenoxy)ethoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trione
0
aromatic ether;
C-nitro compound		00low000000
4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine
0
aromatic ether00low000000
2-[2-(3-ethylphenoxy)ethyl]propanedioic acid diethyl ester
0
aromatic ether00low000000
2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] ester
0
aromatic ether00low000000
1-[3-(2-bromo-4-chlorophenoxy)propyl]-4-methylpiperidine
0
aromatic ether00low000000
N4-(2-methoxyphenyl)benzene-1,4-diamine
0
aromatic ether;
substituted aniline		00low000000
4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester
0
aromatic ether00low000000
2-phenoxybenzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester
0
aromatic ether00low000000
1-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanone
0
aromatic ether00low000000
N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-2-(2-methylphenoxy)-N-(2-methylpropyl)acetamide
0
aromatic ether00low000000
4-[[6-[(2-methyl-5-thieno[2,3-e][1,3]benzothiazolyl)oxy]-3-pyridinyl]sulfonyl]morpholine
0
aromatic ether00low000000
5-(3-fluorophenoxy)-8-nitroisoquinoline
0
aromatic ether00low000000
1-[4-(2-prop-2-enylphenoxy)butyl]pyrrolidine
0
aromatic ether00low000000
2-(2,4-dibromophenoxy)-N-[oxo-(propan-2-ylamino)methyl]acetamide
0
aromatic ether00low000000
4-phenoxyphenyl 4-hydroxypiperidine-1-carboxylate
0
aromatic ether00low000000
N'-benzoyl-5-(3,5-dichlorophenoxy)-2-furancarbohydrazide
0
aromatic ether00low000000
1-[2-[(4-chlorophenoxy)methyl]-4-thiazolyl]ethanone
0
aromatic ether00low000000
5-(benzyloxy)-2-(hydroxymethyl)-1,4-dihydropyridin-4-one
0
aromatic ether00low000000
2-(4-aminophenoxy)isophthalonitrile
0
aromatic ether00low000000
N5-(2-chloro-6-phenoxybenzyl)-1H-1,2,4-triazole-3,5-diamine
0
aromatic ether00low000000
N-[(2-chloro-6-phenoxyphenyl)methyl]benzenesulfonamide
0
aromatic ether00low000000
N-[5-(tert-butyl)-3-isoxazolyl]-N'-[2-(trifluoromethoxy)phenyl]urea
0
aromatic ether00low000000
6-(4-methoxyphenoxy)-2-imidazo[1,2-b]pyridazinecarboxylic acid ethyl ester
0
aromatic ether00low000000
2-fluoro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamide
0
aromatic ether;
C-nitro compound		00low000000
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrile
0
aromatic ether;
C-nitro compound		00low000000
2,4-dichloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide
0
aromatic ether;
C-nitro compound		00low000000
1-anilino-3-[4-(3-anilino-2-hydroxypropoxy)phenoxy]-2-propanol
0
aromatic ether00low000000
1-[4-(3-ethoxyphenoxy)butyl]imidazole
0
aromatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-oxolanecarboxamide
0
aromatic ether00low000000
1-[[2-(2,4-difluorophenoxy)-1-oxopropyl]amino]-3-(2-oxolanylmethyl)thiourea
0
aromatic ether00low000000
N-[[(5-bromo-6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-(2-chlorophenoxy)acetamide
0
aromatic ether00low000000
2-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-methoxy-2-nitrophenyl)acetamide
0
aromatic ether;
C-nitro compound		00low000000
4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxide
0
aromatic ether00low000000
1-(2-fluorophenyl)-3-(4-methoxy-2-nitrophenyl)urea
0
aromatic ether;
C-nitro compound		00low000000
2-[[5-[(2-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamide
0
aromatic ether00low000000
cyclopropanecarboxylic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester
0
aromatic ether00low000000
toremifene
0
aromatic ether;
organochlorine compound;
tertiary amine		antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator		00low000000
dieckol
0
aromatic ether;
oxacycle;
phlorotannin		anticoagulant;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
metabolite;
radical scavenger		00low000000
2-[(2-ethoxyphenoxy)-phenylmethyl]morpholine
0
aromatic ether00low000000
naproxol
0
aromatic etherantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
tamoxifen n-oxide
0
aromatic ether;
tertiary amine oxide		anti-estrogen;
metabolite		00low000000
diafenthiuron
0
aromatic ether;
thiourea acaricide;
thiourea insecticide		oxidative phosphorylation inhibitor;
proinsecticide		00low000000
ospemifene
0
aromatic ether;
organochlorine compound;
primary alcohol		anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator		00low000000
tandutinib
0
aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
piperidines;
quinazolines;
tertiary amino compound		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
zd 6474
0
aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine		antineoplastic agent;
tyrosine kinase inhibitor		00low000000
adefovir
0
aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol		antimalarial;
Aspergillus metabolite;
marine metabolite		00low000000
3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide
0
aromatic ether;
C-nitro compound		00low000000
N-(2-hydroxyethyl)-4-[2-nitro-4-(trifluoromethyl)phenoxy]benzamide
0
aromatic ether00low000000
N'-[2-[(4-amino-5-cyano-2-pyrimidinyl)thio]-1-oxoethyl]-2-(4-methylphenoxy)acetohydrazide
0
aromatic ether00low000000
N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide
0
aromatic ether00low000000
6-amino-4-(2-ethoxy-4-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
aromatic ether;
pyranopyrazole		00low000000
1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylurea
0
aromatic ether00low000000
quinoxyfen
0
aromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines		antifungal agrochemical00low000000
nafadotride
0
aromatic ether;
naphthalenecarboxamide;
nitrile;
pyrrolidines;
tertiary amino compound		dopaminergic antagonist00low000000
1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]urea
0
aromatic ether;
C-nitro compound		00low000000
2-methyl-1,3-bis(phenylmethoxy)benzene
0
aromatic ether00low000000
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea
0
aromatic ether00low000000
3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thione
0
aromatic ether00low000000
2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamide
0
aromatic ether00low000000
5-(benzenesulfonyl)-4-(2,6-dimethylphenoxy)-2-phenylpyrimidine
0
aromatic ether00low000000
4-(2-methylphenoxy)-6-phenylfuro[2,3-d]pyrimidine
0
aromatic ether00low000000
1-[4-(2-chlorophenoxy)butyl]imidazole
0
aromatic ether;
imidazoles;
monochlorobenzenes		00low000000
N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamide
0
aromatic ether;
C-nitro compound		00low000000
N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide
0
aromatic ether;
C-nitro compound		00low000000
N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamide
0
aromatic ether00low000000
hydroxypioglitazone
0
aromatic ether;
pyridines;
thiazolidinediones		human xenobiotic metabolite00low000000
sc 560
0
aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug		00low000000
sc-19220
0
aromatic ether00low000000
5-methyl-4-(3-phenoxyphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-6-carboxylic acid ethyl ester
0
aromatic ether00low000000
8-[4-(4-fluorophenoxy)-3-nitrophenyl]-7-(2-hydroxyethyl)-3-(phenylmethyl)purine-2,6-dione
0
aromatic ether00low000000
2-phenoxybenzoic acid [2-oxo-2-(propan-2-ylamino)ethyl] ester
0
aromatic ether00low000000
2-(4-bromophenoxy)-N'-[2-[(4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]acetohydrazide
0
aromatic ether00low000000
2-(2-methoxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrile
0
aromatic ether;
substituted aniline		00low000000
N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
0
aromatic ether00low000000
5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-ol
0
aromatic ether00low000000
3,3-dimethyl-1,5-dinitro-6-phenoxy-3-azoniabicyclo[3.3.1]non-6-ene
0
aromatic ether00low000000
fraxin
0
aromatic ether;
beta-D-glucoside;
hydroxycoumarin		anti-inflammatory agent;
hepatoprotective agent;
plant metabolite		00low000000
fraxetin
0
aromatic ether;
hydroxycoumarin		anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent		00low000000
5,6-dehydrokawain
0
2-pyranones;
aromatic ether		00low000000
jtk-303
0
aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		HIV-1 integrase inhibitor00low000000
coniferin
0
aromatic ether;
cinnamyl alcohol beta-D-glucoside;
monosaccharide derivative		plant metabolite00low000000
daphnoretin
0
aromatic ether;
hydroxycoumarin		antineoplastic agent;
antiviral agent;
metabolite		00low000000
kavain
0
2-pyranones;
aromatic ether		00low000000
methysticin
0
2-pyranones;
aromatic ether		00low000000
yangonin
0
2-pyranones;
aromatic ether		00low000000
hinokiflavone
0
aromatic ether;
biflavonoid;
hydroxyflavone		antineoplastic agent;
metabolite;
neuroprotective agent		00low000000
gentiacaulein
0
aromatic ether;
polyphenol;
xanthones		plant metabolite00low000000
gentisin
0
aromatic ether;
polyphenol;
xanthones		plant metabolite00low000000
isogentisin
0
aromatic ether;
polyphenol;
xanthones		EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite		00low000000
mangostin
0
aromatic ether;
phenols;
xanthones		antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite		00low000000
1,8-dihydroxy-3,7-dimethoxyxanthone
0
aromatic ether;
polyphenol;
xanthones		plant metabolite00low000000
swerchirin
0
aromatic ether;
phenols;
xanthones		hypoglycemic agent;
metabolite		00low000000
1,2,8-trihydroxy-6-methoxyxanthone
0
aromatic ether;
polyphenol;
xanthones		antioxidant;
plant metabolite		00low000000
wedelolactone
0
aromatic ether;
coumestans;
delta-lactone;
polyphenol		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite		00low000000
cyhalothrin
0
aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide		00low000000
sofalcone
0
aromatic ether;
chalcones;
monocarboxylic acid		anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite		00low000000
pibutidine
0
aromatic ether;
cyclobutenones;
olefinic compound;
piperidines;
primary amino compound;
pyridines;
secondary amino compound		anti-ulcer drug;
H2-receptor antagonist		00low000000
purmorphamine
0
aromatic ether;
morpholines;
purines;
secondary amino compound		osteogenesis regulator;
SMO receptor agonist		00low000000
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile
0
aromatic ether00low000000
ro 41-5253
0
aromatic ether;
benzoic acids;
sulfone;
thiochromane		apoptosis inducer;
retinoic acid receptor alpha antagonist		00low000000
glycycoumarin
0
aromatic ether;
coumarins;
resorcinols		antispasmodic drug;
plant metabolite		00low000000
isoginkgetin
0
aromatic ether;
biflavonoid		antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
plant metabolite		00low000000
neoglycyrol
0
aromatic ether;
coumestans;
delta-lactone;
polyphenol		antineoplastic agent;
plant metabolite		00low000000
rhamnazin
0
aromatic ether;
dimethoxyflavone;
phenols;
trihydroxyflavone		antineoplastic agent;
plant metabolite		00low000000
bosutinib
0
aminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound		antineoplastic agent;
tyrosine kinase inhibitor		00low000000
bw b70c
0
aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor00low000000
lichexanthone
0
aromatic ether;
phenols;
xanthones		plant metabolite00low000000
alternariol monomethyl ether
0
aromatic ether;
benzochromenone		antifungal agent;
fungal metabolite;
mycotoxin		00low000000
decussatin
0
aromatic ether;
phenols;
xanthones		plant metabolite00low000000
bedaquiline
0
aromatic ether;
naphthalenes;
organobromine compound;
quinolines;
tertiary alcohol;
tertiary amino compound		antitubercular agent;
ATP synthase inhibitor		00low000000
dimethomorph
0
aromatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide		00low000000
benanomicin b
0
aromatic ether;
disaccharide derivative;
L-alanine derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol		00low000000
pradimicin b
0
aromatic ether;
L-alanine derivative;
monosaccharide derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol		00low000000
1,7-dihydroxy-4-methoxyxanthone
0
aromatic ether;
phenols;
xanthones		metabolite;
plant metabolite		00low000000
pradimicin a
0
aromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol		00low000000
clodinafop
0
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines		EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
phenoxy herbicide		00low000000
ici 118551
0
aromatic ether;
indanes;
secondary alcohol;
secondary amino compound		beta-adrenergic antagonist00low000000
ochnaflavone
0
aromatic ether;
biflavonoid;
hydroxyflavone		anti-inflammatory agent;
antiatherogenic agent;
antibacterial agent;
EC 3.1.1.4 (phospholipase A2) inhibitor;
leukotriene antagonist;
plant metabolite		00low000000
3-(4-fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene 1-oxide
0
aromatic ether00low000000
flavasperone
0
aromatic ether;
naphtho-gamma-pyrone;
phenols		acyl-CoA:cholesterol acyltransferase 2 inhibitor;
antiviral agent;
Aspergillus metabolite;
marine metabolite		00low000000
4-hydroxycordoin
0
aromatic ether;
chalcones;
polyphenol		anti-inflammatory agent;
antibacterial agent;
plant metabolite		00low000000
n-feruloylserotonin
0
aromatic ether;
cinnamamides;
hydroxyindoles;
phenols;
secondary carboxamide		plant metabolite00low000000
tyrphostin ag825
0
aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide		epidermal growth factor receptor antagonist00low000000
kresoxim-methyl
0
aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic		00low000000
5-methoxy-3,6-diphenyl-1,2,4-triazine
0
aromatic ether00low000000
pyrachlostrobin
0
aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic		00low000000
piericidin a
0
aromatic ether;
methylpyridines;
monohydroxypyridine;
secondary allylic alcohol		antimicrobial agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor;
mitochondrial respiratory-chain inhibitor		00low000000
metrafenone
0
aromatic ether;
aryl phenyl ketone fungicide;
benzophenones;
organobromine compound		antifungal agrochemical00low000000
2-(4-fluoro-3-(trifluoromethyl)phenoxy)-n-(phenylmethyl)butanamide
0
(trifluoromethyl)benzenes;
aromatic ether;
monocarboxylic acid amide;
monofluorobenzenes		00low000000
b 43
0
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
5-ia-85380
0
aromatic ether00low000000
yunaconitine
0
acetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound		antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic		00low000000
ru 58668
0
17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
organofluorine compound;
sulfone		anti-estrogen;
antineoplastic agent;
estrogen receptor antagonist		00low000000
altenusin
0
aromatic ether;
carboxybiphenyl;
catechols;
hydroxybiphenyls;
polyphenol		antifungal agent;
fungal metabolite		00low000000
gw 501516
0
1,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound		carcinogenic agent;
PPARbeta/delta agonist		00low000000
bay 58-2667
0
aromatic ether;
benzoic acids;
dicarboxylic acid;
tertiary amino compound		antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
camostat
0
aromatic ether;
phenols		00low000000
lenvatinib
0
aromatic amide;
aromatic ether;
cyclopropanes;
monocarboxylic acid amide;
monochlorobenzenes;
phenylureas;
quinolines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist;
orphan drug;
vascular endothelial growth factor receptor antagonist		00low000000
nsc 716970
0
aromatic amine;
aromatic ether;
indolecarboxamide;
organochlorine compound		antineoplastic agent00low000000
lobeglitazone
0
aromatic ether00low000000
noviflumuron
0
aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound		00low000000
etomoxir
0
aromatic ether00low000000
fr 148083
0
aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone		antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor		00low000000
9-methoxycanthin-6-one
0
aromatic ether;
indole alkaloid;
organic heterotetracyclic compound		antineoplastic agent;
antiplasmodial drug;
metabolite		00low000000
sb 3ct compound
0
aromatic ether00low000000
dapagliflozin
0
aromatic ether;
C-glycosyl compound;
monochlorobenzenes		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor		00low000000
naveglitazar
0
aromatic ether00low000000
tivozanib
0
aromatic ether00low000000
zm 447439
0
aromatic ether;
benzamides;
morpholines;
polyether;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor		00low000000
ustiloxin b
0
aromatic ether;
heterodetic cyclic peptide;
macrocycle;
phenols;
secondary alcohol;
secondary carboxamide;
sulfoxide		Aspergillus metabolite;
microtubule-destabilising agent;
mycotoxin		00low000000
hypothemycin
0
aromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone		antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite		00low000000
tryprostatin a
0
aromatic ether;
dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine		breast cancer resistance protein inhibitor00low000000
cediranib
0
aromatic ether00low000000
3-iodothyronamine
0
aromatic ether00low000000
n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride
0
aromatic ether;
hydrochloride;
methoxybenzenes;
tertiary amino compound		antipsychotic agent;
receptor modulator		00low000000
rubraxanthone
0
aromatic ether;
polyphenol;
xanthones		antibacterial agent;
antineoplastic agent;
metabolite		00low000000
7,8-Dihydroyangonin
0
2-pyranones;
aromatic ether		00low000000
sch 51344
0
aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound		antineoplastic agent00low000000
ancistroealaine a
0
aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes		antileishmanial agent;
antiplasmodial drug;
metabolite;
trypanocidal drug		00low000000
pimavanserin
0
aromatic ether;
monofluorobenzenes;
piperidines;
tertiary amino compound;
ureas		5-hydroxytryptamine 2A receptor inverse agonist;
antipsychotic agent;
serotonergic antagonist		00low000000
tolfenpyrad
0
aromatic amide;
aromatic ether;
organochlorine compound;
pyrazole insecticide		agrochemical;
antifungal agent;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor		00low000000
SIS3 free base
0
aromatic ether;
enamide;
isoquinolines;
monocarboxylic acid amide;
pyrrolopyridine;
tertiary carboxamide		Smad3 inhibitor00low000000
apixaban
0
aromatic ether;
lactam;
piperidones;
pyrazolopyridine		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor		00low000000
bibw 2992
0
aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
tyrosine kinase inhibitor		00low000000
dihydrokavain
0
2-pyranones;
aromatic ether		00low000000
troglitazone sulfate
0
aromatic ether;
thiazolidinone		00low000000
arisugacin
0
aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol		antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite		00low000000
saracatinib
0
aromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound		anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent		00low000000
fonsecinone a
0
aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol		antibacterial agent;
Aspergillus metabolite		00low000000
crenolanib
0
aminopiperidine;
aromatic ether;
benzimidazoles;
oxetanes;
quinolines;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
aiphanol
0
aromatic ether;
benzodioxine;
lignan;
stilbenoid		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor00low000000
nigerloxin
0
aromatic ether;
benzamides;
benzoic acids;
phenols;
styrenes		antioxidant;
Aspergillus metabolite;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
radical scavenger		00low000000
msdc-0160
0
aromatic ether00low000000
dihydroxanthohumol
0
aromatic ether;
dihydrochalcones;
polyphenol		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite		00low000000
PB28
0
aromatic ether;
piperazines;
tetralins		anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist		00low000000
7-phloroeckol
0
aromatic ether;
phlorotannin		antioxidant;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
metabolite		00low000000
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside
0
aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol		antineoplastic agent;
metabolite		00low000000
PDGF receptor tyrosine kinase inhibitor III
0
aromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
quinazolines;
tertiary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor00low000000
fluoxastrobin
0
aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor		00low000000
flumorph
0
aromatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide		00low000000
regorafenib
0
(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide		antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor		00low000000
erastin
0
aromatic ether;
diether;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
quinazolines;
tertiary carboxamide		antineoplastic agent;
ferroptosis inducer;
voltage-dependent anion channel inhibitor		00low000000
brivanib
0
aromatic ether;
diether;
fluoroindole;
pyrrolotriazine;
secondary alcohol		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
drug metabolite;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist		00low000000
fg-4592
0
aromatic ether;
isoquinolines;
N-acylglycine		EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor		00low000000
picoxystrobin
0
aromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor		00low000000
cenicriviroc
0
aromatic ether;
benzazocine;
diether;
imidazoles;
secondary carboxamide;
sulfoxide		anti-HIV agent;
anti-inflammatory agent;
antirheumatic drug;
chemokine receptor 2 antagonist;
chemokine receptor 5 antagonist		00low000000
mandipropamid
0
aromatic ether;
monocarboxylic acid amide;
monochlorobenzenes;
terminal acetylenic compound		00low000000
glyceryl ferulate
0
1-monoglyceride;
aromatic ether;
enoate ester;
phenols		antioxidant;
plant metabolite;
ultraviolet filter		00low000000
ki 8751
0
aromatic ether00low000000
ceratamine a
0
alkaloid;
aromatic ether;
cyclic ketone;
organic heterobicyclic compound;
organobromine compound;
secondary amino compound;
tertiary amine		antimitotic;
metabolite		00low000000
azd 8931
0
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
tertiary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist		00low000000
bay94 9172
0
(18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline		radioactive imaging agent00low000000
olodaterol
0
aromatic ether;
benzoxazine;
phenols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent		00low000000
dorsomorphin
0
aromatic ether;
piperidines;
pyrazolopyrimidine;
pyridines		bone morphogenetic protein receptor antagonist;
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor		00low000000
cj-042794
0
aromatic ether00low000000
hu 308
0
aromatic ether;
bridged compound;
carbobicyclic compound;
primary allylic alcohol;
synthetic cannabinoid		anti-inflammatory agent;
antihypertensive agent;
apoptosis inhibitor;
bone density conservation agent;
CB2 receptor agonist		00low000000
ki11502
0
aromatic ether;
benzamides;
quinolines;
thioureas		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
apremilast
0
aromatic ether;
N-acetylarylamine;
phthalimides;
sulfone		non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor		00low000000
PF-00835231
0
aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
0
aminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate		antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
chir-265
0
aromatic ether00low000000
aminocandin
0
aromatic ether;
echinocandin;
homodetic cyclic peptide		antiinfective agent00low000000
zk 756326
0
aromatic ether00low000000
bay 60-6583
0
aminopyridine;
aromatic ether;
aryl sulfide;
cyanopyridine;
cyclopropanes;
monocarboxylic acid amide		adenosine A2B receptor agonist;
anti-inflammatory agent;
cardioprotective agent		00low000000
empagliflozin
0
aromatic ether;
C-glycosyl compound;
monochlorobenzenes;
tetrahydrofuryl ether		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor		00low000000
4-[5-(4-ethoxyphenyl)-3-isoxazolyl]-N-[(4-methylphenyl)methyl]butanamide
0
aromatic ether00low000000
bgt226
0
aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		00low000000
n-desmethylrosiglitazone
0
aromatic ether00low000000
4-(5-methyl-3-nitro-1-pyrazolyl)-N-[3-(4-methylphenoxy)-5-nitrophenyl]butanamide
0
aromatic ether00low000000
verruculogen
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker		00low000000
1-O-feruloyl-beta-D-glucose
0
aromatic ether;
beta-D-glucoside;
cinnamate ester;
phenols		antioxidant;
plant metabolite		00low000000
2,2',4,5'-tetrabromodiphenyl ether
0
aromatic ether;
organobromine compound		00low000000
hexabromodiphenyl ether 154
0
aromatic ether;
organobromine compound		00low000000
bde 183
0
aromatic ether;
organobromine compound		00low000000
l-798106
0
aromatic ether;
bromobenzenes;
N-sulfonylcarboxamide		prostaglandin receptor antagonist00low000000
aflatoxin m1
0
aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol		Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite		00low000000
macitentan
0
aromatic ether;
organobromine compound;
pyrimidines;
ring assembly;
sulfamides		antihypertensive agent;
endothelin receptor antagonist;
orphan drug		00low000000
CDN1163
0
aromatic ether;
quinolines;
secondary carboxamide		SERCA activator00low000000
e 7050
0
aromatic ether00low000000
N-[(5-chloro-2-thiophenyl)methyl]-5-[(2,6-difluorophenoxy)methyl]-3-isoxazolecarboxamide
0
aromatic ether00low000000
dafadine C
0
aromatic amide;
aromatic ether;
difluorobenzene;
isoxazoles;
N-acylpiperidine;
pyridines		P450 inhibitor00low000000
dafadine B
0
aromatic amide;
aromatic ether;
isoxazoles;
monochlorobenzenes;
monofluorobenzenes;
N-acylpiperidine;
pyridines		P450 inhibitor00low000000
3-[5-(5-methyl-2-thiophenyl)-1,3,4-oxadiazol-2-yl]-N-[2-(3-pyridinyloxy)propyl]propanamide
0
aromatic ether00low000000
violaceol II
0
aromatic ether;
catechols;
resorcinols		mycotoxin00low000000
pamapimod
0
aromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound		antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
gsk690693
0
1,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
cnf 2024
0
2-aminopurines;
aromatic ether;
organochlorine compound;
pyridines		antineoplastic agent;
Hsp90 inhibitor		00low000000
uk 453,061
0
aromatic ether00low000000
8-{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one
0
aromatic ether;
coumarins;
pyrrolidines;
tertiary amino compound		00low000000
zm323881
0
aromatic ether;
benzyl ether;
fluorophenol;
halophenol;
monofluorobenzenes;
organic cation;
quinazolines;
secondary amino compound;
substituted aniline		vascular endothelial growth factor receptor antagonist00low000000
compound w
0
aromatic ether00low000000
2-[[4-[2-[(2-methylpropan-2-yl)oxy]anilino]-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol
0
aromatic ether00low000000
interiotherin b
0
aromatic ether;
fatty acid ester;
lignan;
organic heteropentacyclic compound;
oxacycle		anti-HIV agent;
metabolite		00low000000
5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one
0
aromatic ether;
homoisoflavonoid;
polyphenol		angiogenesis modulating agent;
plant metabolite		00low000000
ph 797804
0
aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone		anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
diorcinol
0
aromatic ether;
phenols		fungal metabolite;
marine metabolite;
metabolite		00low000000
2-[[4-(2-phenoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol
0
aromatic ether00low000000
2-[[4-(1-pyrrolidinyl)-6-[2-(trifluoromethoxy)anilino]-1,3,5-triazin-2-yl]amino]ethanol
0
aromatic ether00low000000
2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol
0
aromatic ether00low000000
2-[[4-(5-chloro-2-propan-2-yloxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol
0
aromatic ether00low000000
mk 5108
0
aromatic ether00low000000
lde225
0
aminopyridine;
aromatic ether;
benzamides;
biphenyls;
morpholines;
organofluorine compound;
tertiary amino compound		antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist		00low000000
1-azepanyl-[5-[(4-chloro-3,5-dimethylphenoxy)methyl]-3-isoxazolyl]methanone
0
aromatic ether00low000000
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines		geroprotector;
P450 inhibitor		00low000000
dafadine D
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
organofluorine compound;
pyridines		P450 inhibitor00low000000
1-[(1-ethyl-3-methyl-4-pyrazolyl)methyl]-N-[4-(2-fluorophenoxy)phenyl]-4-piperidinecarboxamide
0
aromatic ether00low000000
dafadine O
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines;
ring assembly		P450 inhibitor00low000000
5-[(3,4-dimethylphenoxy)methyl]-N-methyl-N-(4-oxanylmethyl)-3-isoxazolecarboxamide
0
aromatic ether00low000000
pci 32765
0
acrylamides;
aromatic amine;
aromatic ether;
N-acylpiperidine;
pyrazolopyrimidine;
tertiary carboxamide		antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor		00low000000
florbetapir f 18
0
(18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline		radioactive imaging agent00low000000
AMG-208
0
aromatic ether;
quinolines;
triazolopyridazine		antineoplastic agent;
c-Met tyrosine kinase inhibitor		00low000000
6-methoxyspirotryprostatin b
0
aromatic ether;
azaspiro compound;
indole alkaloid;
indolones		antineoplastic agent;
Aspergillus metabolite		00low000000
lucitanib
0
aromatic ether;
cyclopropanes;
naphthalenecarboxamide;
primary amino compound;
quinolines		antineoplastic agent;
fibroblast growth factor receptor antagonist;
vascular endothelial growth factor receptor antagonist		00low000000
act-132577
0
aromatic ether;
organobromine compound;
pyrimidines;
sulfamides		antihypertensive agent;
drug metabolite;
endothelin receptor antagonist;
xenobiotic metabolite		00low000000
cabozantinib
0
aromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines		antineoplastic agent;
tyrosine kinase inhibitor		00low000000
poziotinib
0
acrylamides;
aromatic ether;
dichlorobenzene;
diether;
monofluorobenzenes;
N-acylpiperidine;
quinazolines;
secondary amino compound;
substituted aniline		antineoplastic agent;
apoptosis inducer;
epidermal growth factor receptor antagonist		00low000000
gsk 2126458
0
aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent		00low000000
gsk 1363089
0
aromatic ether00low000000
1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylurea
0
aromatic ether00low000000
1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-propan-2-ylurea
0
aromatic ether00low000000
3-cyclohexyl-1-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea
0
aromatic ether00low000000
3-cyclohexyl-1-[[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-10-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylurea
0
aromatic ether00low000000
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamide
0
aromatic ether00low000000
1-(3,5-dimethyl-4-isoxazolyl)-3-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea
0
aromatic ether00low000000
monepantel
0
(trifluoromethyl)benzenes;
aromatic ether;
aryl sulfide;
nitrile;
secondary carboxamide		anthelminthic drug;
nematicide		00low000000
an2728
0
aromatic ether;
benzoxaborole;
nitrile		antipsoriatic;
non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor		00low000000
grazoprevir
0
aromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative		antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent		00low000000
hordatine a
0
aromatic ether;
benzofurans;
dicarboxylic acid diamide;
guanidines;
phenols		adrenergic antagonist;
metabolite		00low000000
kavain
0
2-pyranones;
aromatic ether		00low000000
5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone
0
aromatic ether00low000000
tak-632
0
(trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor		00low000000
lrrk2-in1
0
aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
quinolobactin
0
aromatic ether;
monohydroxyquinoline;
phenols;
quinolinemonocarboxylic acid		bacterial metabolite;
siderophore		00low000000
AZD1979
0
aromatic ether;
azaspiro compound;
carboxamide;
N-acylazetidine;
oxadiazole;
oxaspiro compound;
oxetanes		melanin-concentrating hormone receptor antagonist00low000000
ML240
0
aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound		antineoplastic agent00low000000
aripiprazole lauroxil
0
aromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone		H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist		00low000000
abt-199
0
aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor		00low000000
xl765
0
aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		00low000000
DMH1
0
aromatic ether;
pyrazolopyrimidine;
quinolines		antineoplastic agent;
bone morphogenetic protein receptor antagonist;
protein kinase inhibitor		00low000000
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide
0
aromatic ether;
methylpyridines;
olefinic compound;
quinazolines;
secondary amino compound;
secondary carboxamide;
toluenes		00low000000
pf 4800567
0
aromatic ether;
monochlorobenzenes;
oxanes;
pyrazolopyrimidine		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
propenylphosphonic acid
0
aromatic ether00low000000
abt-333
0
aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide		antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor		00low000000
naloxegol
0
aromatic ether;
organic heteropentacyclic compound;
phenols;
polyether;
tertiary alcohol		cathartic;
mu-opioid receptor antagonist		00low000000
ceritinib
0
aminopyrimidine;
aromatic ether;
organochlorine compound;
piperidines;
secondary amino compound;
sulfone		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
MK-8353
0
aromatic ether;
dihydropyridine;
indazoles;
methyl sulfide;
N-alkylpyrrolidine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
triazoles		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
HG-10-102-01
0
aminopyrimidine;
aromatic ether;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
secondary amino compound		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
N-[(5-methyl-2-furanyl)methylideneamino]-2-phenoxybenzamide
0
aromatic ether00low000000
saroglitazar
0
aromatic ether;
methyl sulfide;
monocarboxylic acid;
pyrroles		hypoglycemic agent;
PPARalpha agonist;
PPARgamma agonist		00low000000
fertaric acid
0
aromatic ether;
cinnamate ester;
dicarboxylic acid;
phenols;
tetraric acid derivative		00low000000
2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol
0
(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
tertiary alcohol;
triazoles		00low000000
pf-06463922
0
aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
DDR1-IN-1
0
(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor00low000000
ldc4297
0
aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound		antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
MLI-2
0
aromatic ether;
cyclopropanes;
indazoles;
morpholines;
pyrimidines;
tertiary amino compound		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
ap20187
0
aromatic ether;
carboxylic ester;
N-acylpiperidine;
tertiary amino compound		ligand00low000000
methysticin
0
2-pyranones;
aromatic ether		00low000000
biliatresone
0
aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols		plant metabolite;
toxin		00low000000
tak 491
0
1,2,4-oxadiazole;
aromatic ether;
benzimidazoles;
carboxylic ester;
cyclic carbonate ester;
dioxolane		angiotensin receptor antagonist;
antihypertensive agent;
prodrug		00low000000
azilsartan
0
1,2,4-oxadiazole;
aromatic ether;
benzimidazolecarboxylic acid		angiotensin receptor antagonist;
antihypertensive agent		00low000000
hydrazinocurcumin
0
aromatic ether;
olefinic compound;
polyphenol;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
mirodenafil
0
aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent		00low000000
cerulomycin
0
aldoxime;
aromatic ether;
bipyridines;
pyridine alkaloid		antineoplastic agent;
bacterial metabolite;
marine metabolite		00low000000
undecylprodigiosin
0
alkaloid;
aromatic ether;
tripyrrole		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent		00low000000
sb-590885
0
aromatic ether;
imidazoles;
ketoxime;
pyridines;
tertiary amino compound		00low000000
2-[[4-(trifluoromethoxy)phenyl]methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one
0
aromatic ether00low000000
PF-07304814
0
aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug		00low000000
5-methoxypsoralen
0
5-methoxyfurocoumarin;
organic heterotricyclic compound;
psoralens		hepatoprotective agent;
plant metabolite		00low000000
trioxsalen
0
psoralensdermatologic drug;
photosensitizing agent		00low000000
ficusin
0
psoralensplant metabolite00low000000
9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-7h-furo(3,2-g)(1)benzopyran-7-one
0
psoralens00low000000
imperatorin
0
psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
rutamarin
0
psoralens00low000000
3-carbethoxypsoralen
0
ethyl ester;
psoralens		00low000000
isopimpinellin
0
psoralens00low000000
isoimperatorin
0
psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
phellopterin
0
psoralens00low000000
oxypeucadanin
0
psoralens00low000000
4-(2,3-Dihydroxy-3-methylbutoxy)furo(3,2-g)chromen-7-one
0
psoralens00low000000
Neobyakangelicol
0
psoralens00low000000
cnidilin
0
psoralens00low000000
3-methyl-5-propyl-7-furo[3,2-g][1]benzopyranone
0
psoralens00low000000
3-(3,5-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl)propanoic acid
0
psoralens00low000000
byakangelicol
0
psoralens00low000000
acetic acid 2-(7-oxo-2,3-dihydrofuro[3,2-g][1]benzopyran-2-yl)propan-2-yl ester
0
psoralens00low000000
bergaptol
0
5-hydroxyfurocoumarin;
psoralens		00low000000
6',7'-dihydroxybergamottin
0
psoralens00low000000
epoxybergamottin
0
psoralens00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
gallic acid
0
trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite		00low000000
creatine
0
glycine derivative;
guanidines;
zwitterion		geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical		00low000000
dimethyl sulfoxide
0
sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger		00low000000
glycerol
0
alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent		00low000000
thioctic acid
0
dithiolanes;
heterocyclic fatty acid;
thia fatty acid		fundamental metabolite;
geroprotector		00low000000
melatonin
0
acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger		00low000000
niacinamide
0
pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor		00low000000
oxaloacetic acid
0
C4-dicarboxylic acid;
oxo dicarboxylic acid		geroprotector;
metabolite		00low000000
spermidine
0
polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector		00low000000
n-(3-(aminomethyl)benzyl)acetamidine
0
aralkylamine;
carboxamidine;
primary amino compound		angiogenesis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector		00low000000
2,4-dinitrophenol
0
dinitrophenolallergen;
antiseptic drug;
bacterial xenobiotic metabolite;
geroprotector;
oxidative phosphorylation inhibitor		00low000000
mercaptoethanol
0
alkanethiol;
primary alcohol		geroprotector00low000000
3,4-dichloroisocoumarin
0
isocoumarins;
organochlorine compound		geroprotector;
serine protease inhibitor		00low000000
cgp 52411
0
phthalimidesgeroprotector;
tyrosine kinase inhibitor		00low000000
4-phenyl-3-furoxancarbonitrile
0
1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
acetaminophen
0
acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic		00low000000
ag 1295
0
quinoxaline derivativegeroprotector00low000000
rtki cpd
0
aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector		00low000000
tyrphostin a1
0
methoxybenzenesgeroprotector00low000000
amoxapine
0
dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor		00low000000
aspirin
0
benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent		00low000000
berberine
0
alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker		00low000000
buformin
0
biguanidesantineoplastic agent;
antiviral agent;
geroprotector;
hypoglycemic agent;
radiosensitizing agent		00low000000
caffeine
0
purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic		00low000000
carbonyl cyanide m-chlorophenyl hydrazone
0
hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore		00low000000
celecoxib
0
organofluorine compound;
pyrazoles;
sulfonamide;
toluenes		cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
clofibrate
0
aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist		00low000000
ethosuximide
0
dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker		00low000000
ethoxyquin
0
aromatic ether;
quinolines		antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator		00low000000
carbonyl cyanide p-trifluoromethoxyphenylhydrazone
0
aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore		00low000000
fenofibrate
0
aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
foscarnet
0
carboxylic acid;
one-carbon compound;
phosphonic acids		antiviral drug;
geroprotector;
HIV-1 reverse transcriptase inhibitor;
sodium-dependent Pi-transporter inhibitor		00low000000
fasudil
0
isoquinolines;
N-sulfonyldiazepane		antihypertensive agent;
calcium channel blocker;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
geroprotector;
neuroprotective agent;
nootropic agent;
vasodilator agent		00low000000
ibuprofen
0
monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic		00low000000
juglone
0
hydroxy-1,4-naphthoquinonegeroprotector;
herbicide;
reactive oxygen species generator		00low000000
nsc 664704
0
indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector		00low000000
kinetin
0
6-aminopurines;
furans		cytokinin;
geroprotector		00low000000
lamotrigine
0
1,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic		00low000000
loratadine
0
benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist		00low000000
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
0
chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector		00low000000
metformin
0
guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic		00low000000
methiothepin
0
aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist		00low000000
metoprolol
0
aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
mianserin
0
dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist		00low000000
nitrendipine
0
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent		00low000000
masoprocol
0
catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite		00low000000
oxatomide
0
benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist		00low000000
pd 98059
0
aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
pioglitazone
0
aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic		00low000000
ag 1879
0
aromatic amine;
monochlorobenzenes;
pyrazolopyrimidine		beta-adrenergic antagonist;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
resveratrol
0
polyphenol;
resorcinols;
stilbenol		antioxidant;
geroprotector;
glioma-associated oncogene inhibitor;
phytoalexin		00low000000
4-phenylbutyric acid, sodium salt
0
organic sodium saltEC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector;
neuroprotective agent;
orphan drug;
prodrug		00low000000
trimethadione
0
oxazolidinoneanticonvulsant;
geroprotector		00low000000
tyrphostin a9
0
alkylbenzenegeroprotector00low000000
nad
0
NADgeroprotector00low000000
chloramphenicol
0
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		00low000000
promethazine hydrochloride
0
hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative		00low000000
edetic acid
0
ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector		00low000000
cysteamine
0
amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent		00low000000
dimethylnitrosamine
0
nitrosaminegeroprotector;
mutagen		00low000000
dimethylformamide
0
formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent		00low000000
pantothenic acid
0
pantothenic acid;
vitamin B5		antidote to curare poisoning;
geroprotector;
human blood serum metabolite		00low000000
trehalose
0
trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
phenformin
0
biguanidesantineoplastic agent;
geroprotector;
hypoglycemic agent		00low000000
pyrazolanthrone
0
anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector		00low000000
cyproterone acetate
0
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin		00low000000
lithocholic acid
0
bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite		00low000000
naphthazarin
0
hydroxy-1,4-naphthoquinoneacaricide;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
geroprotector;
plant metabolite		00low000000
4-hydroxyphenylethanol
0
phenolsanti-arrhythmia drug;
antioxidant;
cardiovascular drug;
fungal metabolite;
geroprotector;
plant metabolite;
protective agent		00low000000
acetylcysteine
0
acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary		00low000000
dibromoacetic acid
0
2-bromocarboxylic acid;
monocarboxylic acid		apoptosis inducer;
geroprotector;
marine metabolite		00low000000
2-(2'-hydroxyphenyl)benzoxazole
0
1,3-benzoxazoles;
phenols		geroprotector00low000000
ethidium bromide
0
organic bromide saltgeroprotector;
intercalator;
trypanocidal drug		00low000000
paraquat
0
organic cationgeroprotector;
herbicide		00low000000
thioflavin t
0
organic chloride saltfluorochrome;
geroprotector;
histological dye		00low000000
2-(2-hydroxyphenyl)benzothiazole
0
benzothiazoles;
phenols		geroprotector00low000000
selegiline
0
selegiline;
terminal acetylenic compound		geroprotector00low000000
danazol
0
17beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector		00low000000
metergoline
0
carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist		00low000000
butylated hydroxytoluene
0
phenolsantioxidant;
ferroptosis inhibitor;
food additive;
geroprotector		00low000000
bezafibrate
0
aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
lonidamine
0
dichlorobenzene;
indazoles;
monocarboxylic acid		antineoplastic agent;
antispermatogenic agent;
EC 2.7.1.1 (hexokinase) inhibitor;
geroprotector		00low000000
nicardipine hydrochloride
0
dihydropyridinegeroprotector00low000000
acarbose
0
tetrasaccharide derivativeEC 3.2.1.1 (alpha-amylase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
geroprotector;
hypoglycemic agent		00low000000
staurosporine
0
indolocarbazole alkaloid;
organic heterooctacyclic compound		apoptosis inducer;
bacterial metabolite;
EC 2.7.11.13 (protein kinase C) inhibitor;
geroprotector		00low000000
pergolide mesylate
0
methanesulfonate saltantiparkinson drug;
dopamine agonist;
geroprotector		00low000000
simvastatin
0
delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug		00low000000
doxazosin mesylate
0
methanesulfonate saltgeroprotector00low000000
ursolic acid
0
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		geroprotector;
plant metabolite		00low000000
epigallocatechin gallate
0
flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite		00low000000
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose
0
gallate ester;
galloyl beta-D-glucose		anti-inflammatory agent;
antineoplastic agent;
geroprotector;
hepatoprotective agent;
plant metabolite;
radiation protective agent;
radical scavenger		00low000000
pyrrolidine dithiocarbamate
0
dithiocarbamic acids;
pyrrolidines		anticonvulsant;
antineoplastic agent;
geroprotector;
neuroprotective agent;
NF-kappaB inhibitor;
radical scavenger		00low000000
thioridazine hydrochloride
0
hydrochloridefirst generation antipsychotic;
geroprotector		00low000000
mianserin hydrochloride
0
hydrochloridegeroprotector00low000000
alfatradiol
0
17alpha-hydroxy steroid;
3-hydroxy steroid;
estradiol		estrogen;
geroprotector		00low000000
dipropylacetamide
0
fatty amidegeroprotector;
metabolite;
teratogenic agent		00low000000
loxapine succinate
0
succinate saltgeroprotector00low000000
guanfacine hydrochloride
0
acetamidesgeroprotector00low000000
amperozide
0
diarylmethane;
monofluorobenzenes;
N-alkylpiperazine;
secondary carboxamide;
ureas		anxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist		00low000000
amperozide hydrochloride
0
hydrochlorideanxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist		00low000000
2-(1H-benzimidazol-2-yl)aniline
0
benzimidazoles;
primary arylamine;
substituted aniline		geroprotector00low000000
methionine sulfoximine
0
L-alpha-amino acid zwitterion;
L-methionine derivative;
methionine sulfoximine;
non-proteinogenic L-alpha-amino acid		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
geroprotector		00low000000
thiazolidine-4-carboxylic acid, (r)-isomer
0
thiazolidinemonocarboxylic acid;
thioproline		geroprotector;
metabolite		00low000000
paxilline
0
diterpene alkaloid;
enone;
organic heterohexacyclic compound;
terpenoid indole alkaloid;
tertiary alcohol		anticonvulsant;
Aspergillus metabolite;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor;
genotoxin;
geroprotector;
mycotoxin;
Penicillium metabolite;
potassium channel blocker		00low000000
catechin
0
hydrategeroprotector00low000000
nitroflurbiprofen
0
biphenyls;
carboxylic ester;
nitrate ester;
organofluorine compound		cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector;
non-steroidal anti-inflammatory drug;
vasodilator agent		00low000000
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine
0
(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist		00low000000
fullerene c60
0
fullerenegeroprotector00low000000
oxoline
0
aromatic ketone;
tetralins		geroprotector00low000000
sb 203580
0
imidazoles;
monofluorobenzenes;
pyridines;
sulfoxide		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent		00low000000
latrepirdine
0
methylpyridines;
pyridoindole		geroprotector00low000000
vincristine sulfate
0
organic sulfate saltantineoplastic agent;
geroprotector		00low000000
wortmannin
0
acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent		00low000000
lithium chloride
0
inorganic chloride;
lithium salt		antimanic drug;
geroprotector		00low000000
glucosamine
0
D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite		00low000000
carnosine
0
amino acid zwitterion;
dipeptide		anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent		00low000000
theanine
0
amino acid zwitterion;
N(5)-alkyl-L-glutamine		geroprotector;
neuroprotective agent;
plant metabolite		00low000000
nicotinamide-beta-riboside
0
N-glycosylnicotinamide;
pyridine nucleoside		geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
nortriptyline hydrochloride
0
organic tricyclic compoundgeroprotector00low000000
kanamycin sulfate
0
aminoglycoside sulfate saltantibacterial drug;
geroprotector		00low000000
glaucarubinone
0
carboxylic ester;
organic heteropentacyclic compound;
quassinoid;
secondary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone;
tetrol		antimalarial;
antineoplastic agent;
geroprotector;
plant metabolite		00low000000
vinpocetine
0
alkaloidgeroprotector00low000000
dihydroergocristine monomesylate
0
methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent		00low000000
trichostatin a
0
antibiotic antifungal agent;
hydroxamic acid;
trichostatin		bacterial metabolite;
EC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector		00low000000
fumaric acid
0
butenedioic acidfood acidity regulator;
fundamental metabolite;
geroprotector		00low000000
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
0
carbotetracyclic compound;
polyphenol		estrogen receptor agonist;
estrogen receptor antagonist;
geroprotector;
neuroprotective agent		00low000000
isoliquiritigenin
0
chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist		00low000000
3,3',4,5'-tetrahydroxystilbene
0
catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor		00low000000
caffeic acid
0
caffeic acidgeroprotector;
mouse metabolite		00low000000
curcumin
0
aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger		00low000000
cinnarizine
0
diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist		00low000000
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene
0
C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector		00low000000
brl 15572
0
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist		00low000000
ly 367265
0
dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor		00low000000
sodium butyrate
0
organic sodium saltEC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector		00low000000
quercetin
0
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		00low000000
cholecalciferol
0
D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone		geroprotector;
human metabolite		00low000000
quercetin 3-o-glucopyranoside
0
beta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite		00low000000
kaempferol
0
7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite		00low000000
genistein
0
7-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor		00low000000
methylergonovine maleate
0
ergoline alkaloidgeroprotector00low000000
butein
0
chalcones;
polyphenol		antineoplastic agent;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
geroprotector;
hypoglycemic agent;
plant metabolite;
radiosensitizing agent;
tyrosine kinase inhibitor		00low000000
baicalein
0
trihydroxyflavoneangiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger		00low000000
fisetin
0
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		00low000000
myricetin
0
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		00low000000
polydatin
0
beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		anti-arrhythmia drug;
antioxidant;
geroprotector;
hepatoprotective agent;
metabolite;
nephroprotective agent;
potassium channel modulator		00low000000
chicoric acid
0
organooxygen compoundgeroprotector;
HIV-1 integrase inhibitor		00low000000
rosmarinic acid
0
rosmarinic acidgeroprotector;
plant metabolite		00low000000
ellagic acid
0
catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent		00low000000
cis-flupenthixol dihydrochloride
0
hydrochloridegeroprotector00low000000
n-oleoylethanolamine
0
endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist		00low000000
cyclosporine
0
homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite		00low000000
sirolimus
0
antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		00low000000
morphine
0
morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic		00low000000
kn 93
0
monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector		00low000000
10-hydroxy-2-decenoic acid
0
alpha,beta-unsaturated monocarboxylic acid;
hydroxy monounsaturated fatty acid;
omega-hydroxy-medium-chain fatty acid;
straight-chain fatty acid		animal metabolite;
geroprotector		00low000000
ag-490
0
catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor		00low000000
methyl 2,5-dihydroxycinnamate
0
cinnamate ester;
hydroquinones;
methyl ester		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
geroprotector;
human urinary metabolite;
plant metabolite		00low000000
enalapril
0
dicarboxylic acid monoester;
dipeptide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
geroprotector;
prodrug		00low000000
3,8-dihydroxy-6h-dibenzo(b,d)pyran-6-one
0
coumarinsgeroprotector00low000000
guanabenz acetate
0
dichlorobenzenegeroprotector00low000000
everolimus
0
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
primary alcohol;
secondary alcohol		anticoronaviral agent;
antineoplastic agent;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		00low000000
l 744832
0
benzenes;
ether;
isopropyl ester;
secondary carboxamide;
sulfone;
thiol		antineoplastic agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
geroprotector		00low000000
b 43
0
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
3,3-diethyl-2-pyrrolidinone
0
pyrrolidin-2-onesanticonvulsant;
geroprotector		00low000000
n,n'-dibenzhydrylethane-1,2-diamine dihydrochloride
0
hydrochloridegeroprotector;
metabotropic glutamate receptor agonist;
neuroprotective agent		00low000000
trametinib
0
acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
valproate sodium
0
organic sodium saltgeroprotector00low000000
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines		geroprotector;
P450 inhibitor		00low000000
ascorbic acid
0
ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent		00low000000
lfm a13
0
aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor		00low000000
chromium tripicolinate
0
chromium coordination entityanti-obesity agent;
geroprotector;
hypoglycemic agent;
nutraceutical		00low000000
rifampin
0
cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor		00low000000
didanosine
0
purine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor;
geroprotector;
HIV-1 reverse transcriptase inhibitor		00low000000
4-aminopyridine
0
aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker		00low000000
tolazamide
0
N-sulfonylureahypoglycemic agent;
potassium channel blocker		00low000000
tolbutamide
0
N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker		00low000000
tetraethylammonium chloride
0
organic chloride salt;
quaternary ammonium salt		potassium channel blocker00low000000
barium chloride
0
barium salt;
inorganic chloride		potassium channel blocker00low000000
uk 68798
0
aromatic ether;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
potassium channel blocker		00low000000
methionine ethyl ester
0
alpha-amino acid ester;
L-methionine derivative		potassium channel blocker00low000000
ent-diltiazem
0
5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetatepotassium channel blocker00low000000
quinidine
0
cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker		00low000000
NNC 55-0396 (free base)
0
benzimidazoles;
cyclopropanecarboxylate ester;
organofluorine compound;
tertiary amino compound;
tetralins		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
neuroprotective agent;
potassium channel blocker;
T-type calcium channel blocker		00low000000
4-aminopyridine-3-methanol
0
aminopyridine;
aromatic amine;
aromatic primary alcohol		potassium channel blocker00low000000
verruculogen
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker		00low000000
nnc 55-0396
0
hydrochlorideangiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
neuroprotective agent;
potassium channel blocker;
T-type calcium channel blocker		00low000000
spermine
0
polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent		00low000000
phenanthridone
0
lactam;
phenanthridines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
immunosuppressive agent;
mutagen		00low000000
azathioprine
0
aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug		00low000000
chetomin
0
indoles;
organic disulfide;
organic heteropentacyclic compound		Chaetomium metabolite;
immunosuppressive agent		00low000000
chlorambucil
0
aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		00low000000
fluorouracil
0
nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic		00low000000
ifosfamide
0
ifosfamidesalkylating agent;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
xenobiotic		00low000000
leflunomide
0
(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor		00low000000
prednisolone
0
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic		00low000000
prednisone
0
11-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug		00low000000
gliotoxin
0
dipeptide;
organic disulfide;
organic heterotetracyclic compound;
pyrazinoindole		antifungal agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
immunosuppressive agent;
mycotoxin;
proteasome inhibitor		00low000000
cytarabine
0
beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent		00low000000
dimethyl sulfate
0
alkyl sulfatealkylating agent;
immunosuppressive agent		00low000000
scoparone
0
aromatic ether;
coumarins		anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite		00low000000
betamethasone
0
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent		00low000000
triphenyltin chloride
0
chlorine molecular entity;
organotin compound		antifungal agrochemical;
immunosuppressive agent		00low000000
cladribine
0
organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent		00low000000
cyclophosphamide
0
hydratealkylating agent;
antineoplastic agent;
carcinogenic agent;
immunosuppressive agent		00low000000
thiamphenicol
0
monocarboxylic acid amide;
sulfone		antimicrobial agent;
immunosuppressive agent		00low000000
fludarabine phosphate
0
nucleoside analogue;
organofluorine compound;
purine arabinonucleoside monophosphate		antimetabolite;
antineoplastic agent;
antiviral agent;
DNA synthesis inhibitor;
immunosuppressive agent;
prodrug		00low000000
perfosfamide
0
nitrogen mustard;
organochlorine compound;
peroxol;
phosphorodiamide		alkylating agent;
antineoplastic agent;
drug allergen;
immunosuppressive agent;
metabolite		00low000000
brequinar
0
biphenyls;
monocarboxylic acid;
monofluorobenzenes;
quinolinemonocarboxylic acid		anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor;
immunosuppressive agent;
pyrimidine synthesis inhibitor		00low000000
gemcitabine hydrochloride
0
hydrochloride;
organofluorine compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral drug;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
immunosuppressive agent;
radiosensitizing agent		00low000000
gemcitabine
0
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic		00low000000
triptonide
0
butenolide;
cyclic ketone;
diterpene triepoxide;
organic heteroheptacyclic compound		anti-inflammatory agent;
antineoplastic agent;
immunosuppressive agent		00low000000
dexrazoxane
0
razoxaneantineoplastic agent;
cardiovascular drug;
chelator;
immunosuppressive agent		00low000000
flunisolide
0
11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
primary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug;
immunosuppressive agent		00low000000
hydrocortamate
0
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
glucocorticoid;
glycinyl ester;
tertiary alpha-hydroxy ketone		anti-inflammatory drug;
immunosuppressive agent		00low000000
fingolimod hydrochloride
0
hydrochlorideimmunosuppressive agent;
prodrug;
sphingosine-1-phosphate receptor agonist		00low000000
fingolimod
0
aminodiol;
primary amino compound		antineoplastic agent;
CB1 receptor antagonist;
immunosuppressive agent;
prodrug;
sphingosine-1-phosphate receptor agonist		00low000000
methotrexate
0
dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent		00low000000
4'-demethyldesoxypodophyllotoxin
0
furonaphthodioxole;
gamma-lactone;
lignan;
methoxybenzenes;
phenols		antineoplastic agent;
antioxidant;
immunosuppressive agent;
plant metabolite		00low000000
vincaleukoblastine
0
acetate ester;
indole alkaloid fundamental parent;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
immunosuppressive agent;
microtubule-destabilising agent;
plant metabolite		00low000000
tacrolimus
0
macrolide lactambacterial metabolite;
immunosuppressive agent		00low000000
mycophenolic acid
0
2-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic		00low000000
azaserine
0
carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite		00low000000
melphalan
0
L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		00low000000
mycophenolate mofetil
0
carboxylic ester;
ether;
gamma-lactone;
phenols;
tertiary amino compound		anticoronaviral agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
immunosuppressive agent;
prodrug		00low000000
l 683590
0
ether;
lactol;
macrolide;
secondary alcohol		antifungal agent;
bacterial metabolite;
immunosuppressive agent		00low000000
thermozymocidin
0
alpha-amino fatty acid;
hydroxy monocarboxylic acid;
non-proteinogenic alpha-amino acid;
sphingoid		antifungal agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor;
fungal metabolite;
immunosuppressive agent		00low000000
fty 720p
0
monoalkyl phosphate;
primary alcohol;
primary amino compound		antineoplastic agent;
immunosuppressive agent;
sphingosine-1-phosphate receptor agonist		00low000000
sotrastaurin
0
indoles;
maleimides;
N-alkylpiperazine;
N-arylpiperazine;
quinazolines		anticoronaviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunosuppressive agent		00low000000
demethylzeylasteral
0
arenecarbaldehyde;
benzenediols;
carbopolycyclic compound;
cyclic ketone;
enone;
oxo monocarboxylic acid		anti-inflammatory agent;
EC 2.4.1.17 (glucuronosyltransferase) inhibitor;
immunosuppressive agent;
nephroprotective agent;
plant metabolite		00low000000
ginsenoside rd
0
beta-D-glucoside;
ginsenoside;
tetracyclic triterpenoid		anti-inflammatory drug;
apoptosis inducer;
immunosuppressive agent;
neuroprotective agent;
plant metabolite;
vulnerary		00low000000
brequinar sodium
0
organic sodium saltanticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor;
immunosuppressive agent;
pyrimidine synthesis inhibitor		00low000000
baricitinib
0
azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide		anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent		00low000000
euonine
0
acetate ester;
dihydroagarofuran sesquiterpenoid;
macrolide;
pyridine alkaloid;
sesquiterpene alkaloid		immunosuppressive agent;
insecticide;
plant metabolite		00low000000
physalin f
0
enone;
epoxy steroid;
lactone;
physalin		antileishmanial agent;
antimalarial;
antineoplastic agent;
apoptosis inducer;
immunosuppressive agent		00low000000
brasilicardin a
0
benzoate ester;
carbotricyclic compound;
diterpenoid;
N-acetyl-D-glucosaminide;
non-proteinogenic alpha-amino acid;
phenols		antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
immunosuppressive agent		00low000000
undecylprodigiosin
0
alkaloid;
aromatic ether;
tripyrrole		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
4-phenyl-3-furoxancarbonitrile
0
1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
rtki cpd
0
aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector		00low000000
clofibrate
0
aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist		00low000000
ethoxyquin
0
aromatic ether;
quinolines		antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator		00low000000
carbonyl cyanide p-trifluoromethoxyphenylhydrazone
0
aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore		00low000000
fenofibrate
0
aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
metoprolol
0
aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound		antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
pioglitazone
0
aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic		00low000000
bezafibrate
0
aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		00low000000
curcumin
0
aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger		00low000000
l 744832
0
benzenes;
ether;
isopropyl ester;
secondary carboxamide;
sulfone;
thiol		antineoplastic agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
geroprotector		00low000000
b 43
0
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines		geroprotector;
P450 inhibitor		00low000000
uk 68798
0
aromatic ether;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
potassium channel blocker		00low000000
verruculogen
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker		00low000000
scoparone
0
aromatic ether;
coumarins		anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite		00low000000
undecylprodigiosin
0
alkaloid;
aromatic ether;
tripyrrole		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
catechol
1
catecholsallelochemical;
genotoxin;
plant metabolite		2009200915.0low000100
taxifolin
1
3'-hydroxyflavanones;
4'-hydroxyflavanones;
dihydroflavonols;
pentahydroxyflavanone;
secondary alpha-hydroxy ketone		2009200915.0low000100
phosphonoacetic acid
1
monocarboxylic acid;
phosphonic acids		antiviral agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor		2009200915.0low000100
3,4-dihydroxyphenylacetic acid
1
catechols;
dihydroxyphenylacetic acid		human metabolite2009200915.0low000100
hydroquinone
1
benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent		2009200915.0low000100
sk&f-38393
1
benzazepine;
catechols;
secondary amino compound		2009200915.0low000100
1,10-diaminodecane
1
2009200915.0low000100
1,3-dipropyl-8-cyclopentylxanthine
1
oxopurineadenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor		2009200915.0low000100
pk 11195
1
aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent2009200915.0low000100
1-aminobenzotriazole
1
2009200915.0low000100
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one
1
oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor2009200915.0low000100
2,2'-dipyridyl
1
bipyridinechelator;
ferroptosis inhibitor		2009200915.0low000100
3,4-dichloroisocoumarin
1
isocoumarins;
organochlorine compound		geroprotector;
serine protease inhibitor		2009200915.0low000100
cgp 52411
1
phthalimidesgeroprotector;
tyrosine kinase inhibitor		2009200915.0low000100
4-amino-1,8-naphthalimide
1
benzoisoquinoline;
dicarboximide		2009200915.0low000100
homovanillic acid
1
guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite		2009200915.0low000100
4-phenyl-3-furoxancarbonitrile
1
1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		2009200915.0low000100
5-(n,n-hexamethylene)amiloride
1
aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker		2009200915.0low000100
ethylisopropylamiloride
1
aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker		2009200915.0low000100
5-fluoroindole-2-carboxylic acid
1
indolyl carboxylic acid2009200915.0low000100
phenanthridone
1
lactam;
phenanthridines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
immunosuppressive agent;
mutagen		2009200915.0low000100
6-nitroso-1,2-benzopyrone
1
2009200915.0low000100
8-(4-sulfophenyl)theophylline
1
2009200915.0low000100
aa 861
1
1,4-benzoquinones;
acetylenic compound;
primary alcohol		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor		2009200915.0low000100
ag 127
1
nitrophenol2009200915.0low000100
rtki cpd
1
aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector		2009200915.0low000100
tyrphostin a23
1
catechols2009200915.0low000100
tyrphostin 25
1
benzenetriol2009200915.0low000100
amlodipine
1
dihydropyridine;
ethyl ester;
methyl ester;
monochlorobenzenes;
primary amino compound		antihypertensive agent;
calcium channel blocker;
vasodilator agent		2013201311.0low000010
amoxapine
1
dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor		2009200915.0low000100
aurintricarboxylic acid
1
monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist		2009200915.0low000100
azathioprine
1
aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug		2009200915.0low000100
bay-k-8644
1
(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester		2009200915.0low000100
bml 190
1
N-acylindole2009200915.0low000100
brimonidine
1
imidazoles;
quinoxaline derivative;
secondary amine		adrenergic agonist;
alpha-adrenergic agonist;
antihypertensive agent		2009200915.0low000100
bu 224
1
quinolines2009200915.0low000100
cgs 15943
1
aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline		adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant		2009200915.0low000100
chlorambucil
1
aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		2009200915.0low000100
chloroquine
1
aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug		2009200915.0low000100
cilostamide
1
quinolines2009200915.0low000100
cilostazol
1
lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent		2009200915.0low000100
cimetidine
1
aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor		2009200915.0low000100
cinoxacin
1
cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent		2009200915.0low000100
clotrimazole
1
conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic		2009200915.0low000100
diazepam
1
1,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic		2013201311.0low000010
dipyridamole
1
piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent		2009200915.0low000100
disulfiram
1
organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor		2009200915.0low000100
2,3-dimethoxy-1,4-naphthoquinone
1
1,4-naphthoquinones2009200915.0low000100
domperidone
1
benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist		2009200915.0low000100
droperidol
1
aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic		2009200915.0low000100
ebselen
1
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		2009200915.0low000100
ellipticine
1
indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite		2009200915.0low000100
emodin
1
trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor		2009200915.0low000100
felodipine
1
dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent		2009200915.0low000100
fenofibrate
1
aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		2009200915.0low000100
flumazenil
1
ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist		2013201311.0low000010
fluorouracil
1
nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic		2009200915.0low000100
fluoxetine
1
(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound		2013201311.0low000010
fluspirilene
1
diarylmethane2009200915.0low000100
flutamide
1
(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent		2009200915.0low000100
formoterol fumarate
1
formamides;
phenols;
phenylethanolamines;
secondary alcohol;
secondary amino compound		2009200915.0low000100
fpl 64176
1
carboxylic ester;
pyrroles		calcium channel agonist2009200915.0low000100
furosemide
1
chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic		2009200915.0low000100
glyburide
1
monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent		2009200915.0low000100
haloperidol
1
aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist		2009200915.0low000100
ic 261
1
indoles2009200915.0medium000100
lidocaine
1
benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic		2013201311.0low000010
indirubin-3'-monoxime
1
2009200915.0low000100
4-piperidinecarboxylic acid
1
2009200915.0low000100
jl 18
1
2009200915.0low000100
nsc 664704
1
indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector		2009200915.0low000100
ketoconazole
1
dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine		2009200915.0low000100
lansoprazole
1
benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor		2009200915.0low000100
beta-lapachone
1
benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite		2009200915.0low000100
linopirdine
1
indoles2009200915.0low000100
loratadine
1
benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist		2009200915.0low000100
nocodazole
1
aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator		2009200915.0low000100
metolazone
1
organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor		2009200915.0low000100
mitoxantrone
1
dihydroxyanthraquinoneanalgesic;
antineoplastic agent		2009200915.0low000100
ml 7
1
N-sulfonyldiazepane;
organoiodine compound		EC 2.7.11.18 (myosin-light-chain kinase) inhibitor2009200915.0low000100
ml 9
1
naphthalenes;
sulfonic acid derivative		2009200915.0low000100
fg 7142
1
beta-carbolines2009200915.0low000100
n 0840
1
2009200915.0low000100
nialamide
1
organonitrogen compound;
organooxygen compound		2009200915.0low000100
niclosamide
1
benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor		2009200915.0low000100
nifedipine
1
C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent		2009200915.0low000100
nimodipine
1
2-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent		2009200915.0low000100
nitrendipine
1
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent		2009200915.0low000100
masoprocol
1
catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite		2009200915.0low000100
norfluoxetine
1
(trifluoromethyl)benzenes2013201311.0low000010
5-nitro-2-(3-phenylpropylamino)benzoic acid
1
nitrobenzoic acid2009200915.0low000100
ns 1619
1
(trifluoromethyl)benzenes;
benzimidazoles;
phenols		potassium channel opener2009200915.0low000100
ofloxacin
1
3-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline		2009200915.0low000100
olomoucine
1
2,6-diaminopurines;
ethanolamines		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor2009200915.0low000100
oxaprozin
1
1,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug		2009200915.0low000100
oxatomide
1
benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist		2009200915.0low000100
palmidrol
1
endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent		2009200915.0low000100
pd 169316
1
imidazoles2009200915.0low000100
pd 98059
1
aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		2009200915.0low000100
perphenazine
1
N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug		2009200915.0low000100
phenyl biguanide
1
guanidinescentral nervous system drug2009200915.0low000100
phenylbutazone
1
pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug		2009200915.0low000100
phloretin
1
dihydrochalconesantineoplastic agent;
plant metabolite		2009200915.0low000100
picotamide
1
benzamides2009200915.0low000100
pinacidil
1
pyridines2009200915.0low000100
pirenperone
1
aromatic ketone2009200915.0low000100
praziquantel
1
isoquinolines2009200915.0low000100
propentofylline
1
oxopurine2009200915.0low000100
pf 5901
1
quinolines2009200915.0low000100
riluzole
1
benzothiazoles2009200915.0low000100
risperidone
1
1,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist		2009200915.0low000100
ritanserin
1
organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist		2009200915.0low000100
sb 202190
1
imidazoles;
organofluorine compound;
phenols;
pyridines		apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		2009200915.0low000100
spiroxatrine
1
imidazolidines2009200915.0low000100
t0156
1
naphthyridine derivative2009200915.0low000100
terfenadine
1
diarylmethane2009200915.0low000100
tetraisopropylpyrophosphamide
1
phosphoramide2009200915.0low000100
ici 136,753
1
pyrazolopyridine2009200915.0low000100
triamterene
1
pteridinesdiuretic;
sodium channel blocker		2009200915.0low000100
trimethoprim
1
aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic		2009200915.0low000100
tyrphostin a9
1
alkylbenzenegeroprotector2009200915.0low000100
8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine
1
2009200915.0low000100
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
1
aromatic primary alcohol;
furans;
indazoles		antineoplastic agent;
apoptosis inducer;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		2009200915.0low000100
zaleplon
1
nitrile;
pyrazolopyrimidine		anticonvulsant;
anxiolytic drug;
central nervous system depressant;
sedative		2013201311.0low000010
corticosterone
1
11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite		2009200915.0low000100
reserpine
1
alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic		2009200915.0low000100
isoproterenol hydrochloride
1
catechols2009200915.0low000100
spironolactone
1
3-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic		2009200915.0low000100
estrone
1
17-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite		2009200915.0low000100
androsterone
1
17-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone		2009200915.0low000100
promazine hydrochloride
1
hydrochloride2009200915.0low000100
dimethylphenylpiperazinium iodide
1
N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist2009200915.0low000100
racepinephrine hydrochloride
1
2009200915.0low000100
(4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride
1
2009200915.0low000100
cantharidin
1
cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide		2009200915.0low000100
tetraethylammonium chloride
1
organic chloride salt;
quaternary ammonium salt		potassium channel blocker2009200915.0low000100
physostigmine
1
carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic		2009200915.0low000100
promethazine hydrochloride
1
hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative		2009200915.0low000100
methoxamine hydrochloride
1
dimethoxybenzene2009200915.0low000100
papaverine hydrochloride
1
2009200915.0low000100
bretylium tosylate
1
organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent		2009200915.0low000100
androstenedione
1
17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite		2009200915.0low000100
colchicine
1
alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen		2009200915.0low000100
yohimbine hydrochloride
1
2009200915.0low000100
17-alpha-hydroxyprogesterone
1
17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin		2009200915.0low000100
quinacrine monohydrochloride
1
2009200915.0medium000100
chlorpromazine hydrochloride
1
hydrochloride;
phenothiazines		anticoronaviral agent;
phenothiazine antipsychotic drug		2009200915.0low000100
tryptophan
1
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite		2009200915.0low000100
lidocaine hydrochloride
1
hydrochlorideanti-arrhythmia drug;
local anaesthetic		2009200915.0low000100
rotenone
1
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin		2009200915.0low000100
imipramine hydrochloride
1
hydrochlorideantidepressant2009200915.0low000100
suramin sodium
1
organic sodium saltangiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug		2009200915.0low000100
pyrazolanthrone
1
anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector		2009200915.0low000100
methapyrilene hydrochloride
1
hydrochlorideanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative		2009200915.0low000100
2-chloroadenosine
1
purine nucleoside2009200915.0low000100
diphenhydramine hydrochloride
1
hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative		2009200915.0low000100
propantheline bromide
1
xanthenes2009200915.0low000100
pargyline hydrochloride
1
2009200915.0low000100
orphenadrine hydrochloride
1
hydrochlorideantiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic		2009200915.0low000100
betamethasone
1
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent		2009200915.0low000100
benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide
1
2009200915.0low000100
cyproterone acetate
1
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin		2009200915.0low000100
podophyllotoxin
1
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		2009200915.0low000100
tetrahydrozoline hydrochloride
1
hydrochloridenasal decongestant;
sympathomimetic agent;
vasoconstrictor agent		2009200915.0low000100
dequalinium chloride
1
organic chloride saltantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor		2009200915.0low000100
decamethonium dibromide
1
2009200915.0low000100
amitriptyline hydrochloride
1
organic tricyclic compound2009200915.0low000100
naphazoline hydrochloride
1
organic molecular entity2009200915.0low000100
doxylamine succinate
1
organic molecular entity2009200915.0low000100
formestane
1
17-oxo steroid;
3-oxo-Delta(4) steroid;
enol;
hydroxy steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor		2009200915.0low000100
Mecamylamine hydrochloride
1
monoterpenoid2009200915.0medium000100
cyproheptadine hydrochloride (anhydrous)
1
hydrochloride2009200915.0low000100
amiloride
1
aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker		2013201311.0low000010
pimozide
1
benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist		2009200915.0low000100
antazoline hydrochloride
1
2009200915.0low000100
beclomethasone
1
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug		2009200915.0low000100
buthionine sulfoximine
1
diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer		2009200915.0low000100
mexiletine hydrochloride
1
hydrochlorideanti-arrhythmia drug2009200915.0low000100
cyclobenzaprine hydrochloride
1
hydrochlorideantidepressant;
muscle relaxant		2009200915.0low000100
3-deazaadenosine
1
2009200915.0low000100
metoclopramide hydrochloride
1
2009200915.0low000100
isoetharine mesylate
1
2009200915.0low000100
propionylpromazine hydrochloride
1
2009200915.0low000100
camptothecin
1
delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite		2009200915.0low000100
benserazide hydrochloride
1
hydrochlorideantiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor		2009200915.0low000100
pancuronium bromide
1
bromide saltcholinergic antagonist;
muscle relaxant;
nicotinic antagonist		2009200915.0medium000100
tetradecanoylphorbol acetate
1
acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator		2009200915.0low000100
danazol
1
17beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector		2009200915.0low000100
metergoline
1
carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist		2009200915.0low000100
disopyramide phosphate
1
organoammonium phosphate2009200915.0low000100
2-bromoergocryptine mesylate
1
methanesulfonate saltantiparkinson drug2009200915.0medium000100
paclitaxel
1
taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent		2009200915.0low000100
buspirone hydrochloride
1
hydrochlorideanxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist		2009200915.0low000100
etoposide
1
beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor		2009200915.0low000100
propafenone hydrochloride
1
hydrochlorideanti-arrhythmia drug2009200915.0low000100
etazolate hydrochloride
1
2009200915.0low000100
ribavirin
1
1-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor		2009200915.0low000100
carbidopa
1
catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor		2009200915.0low000100
flecainide acetate
1
acetate saltanti-arrhythmia drug2009200915.0low000100
nicardipine hydrochloride
1
dihydropyridinegeroprotector2009200915.0low000100
idarubicin
1
anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative		2009200915.0low000100
terazosin hydrochloride anhydrous
1
2009200915.0low000100
pergolide mesylate
1
methanesulfonate saltantiparkinson drug;
dopamine agonist;
geroprotector		2009200915.0low000100
atomoxetine
1
aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic		2009200915.0low000100
raloxifene hydrochloride
1
hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator		2009200915.0low000100
mifepristone
1
3-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive		2009200915.0low000100
salmeterol xinafoate
1
naphthoic acid2009200915.0low000100
finasteride
1
3-oxo steroid;
aza-steroid;
delta-lactam		androgen antagonist;
antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor		2009200915.0low000100
mibefradil dihydrochloride
1
2009200915.0low000100
eliprodil
1
monochlorobenzenes;
monofluorobenzenes;
piperidines;
secondary alcohol;
tertiary amino compound		2009200915.0low000100
aptiganel hydrochloride
1
2009200915.0low000100
phenelzine sulfate
1
organic molecular entity2009200915.0low000100
fluoxetine hydrochloride
1
hydrochloride;
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine		2009200915.0low000100
propranolol hydrochloride
1
hydrochloride2009200915.0low000100
bupropion hydrochloride
1
aromatic ketone2009200915.0low000100
trazodone hydrochloride
1
hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor		2009200915.0low000100
verapamil hydrochloride
1
2009200915.0low000100
doxazosin mesylate
1
methanesulfonate saltgeroprotector2009200915.0low000100
terfenadine
1
diarylmethane2009200915.0low000100
sertraline hydrochloride
1
hydrochlorideantidepressant;
serotonin uptake inhibitor		2009200915.0low000100
amantadine hydrochloride
1
hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist		2009200915.0low000100
chloroquine diphosphate
1
2009200915.0low000100
dobutamine hydrochloride
1
hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent		2009200915.0low000100
desipramine hydrochloride
1
hydrochloridedrug allergen2009200915.0low000100
dopamine hydrochloride
1
catecholamine2009200915.0low000100
proadifen hydrochloride
1
2009200915.0low000100
4-nitrobenzylthioinosine
1
purine nucleoside2009200915.0low000100
rutecarpine
1
beta-carbolines2009200915.0low000100
trihexyphenidyl hydrochloride
1
aralkylamine2009200915.0low000100
thioridazine hydrochloride
1
hydrochloridefirst generation antipsychotic;
geroprotector		2009200915.0low000100
siquil
1
hydrochlorideanticoronaviral agent2009200915.0low000100
oxymetazoline hydrochloride
1
hydrochloridealpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent		2009200915.0low000100
alprenolol hydrochloride
1
hydrochloride2009200915.0low000100
2-methoxyestradiol
1
17beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite		2009200915.0low000100
fluphenazine hydrochloride
1
phenothiazinesanticoronaviral agent2009200915.0low000100
tryptamine monohydrochloride
1
2009200915.0high000100
clomipramine hydrochloride
1
hydrochlorideanticoronaviral agent;
antidepressant;
serotonergic antagonist;
serotonergic drug		2009200915.0low000100
amiloride hydrochloride
1
hydratediuretic;
sodium channel blocker		2009200915.0low000100
prazosin hydrochloride
1
hydrochloride2009200915.0low000100
mianserin hydrochloride
1
hydrochloridegeroprotector2009200915.0low000100
lomefloxacin hydrochloride
1
hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent		2009200915.0low000100
fenspiride hydrochloride
1
2009200915.0low000100
nilverm
1
organic molecular entity2009200915.0low000100
sanguinarine chloride
1
2009200915.0low000100
ropinirole hydrochloride
1
indoles2009200915.0medium000100
dihydroergotamine mesylate
1
methanesulfonate saltnon-narcotic analgesic;
serotonergic agonist;
vasoconstrictor agent		2009200915.0low000100
ranolazine hydrochloride
1
2009200915.0medium000100
loxapine succinate
1
succinate saltgeroprotector2009200915.0low000100
guanfacine hydrochloride
1
acetamidesgeroprotector2009200915.0low000100
labetalol hydrochloride
1
salicylamides2009200915.0low000100
loperamide hydrochloride
1
hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist		2009200915.0low000100
maprotiline hydrochloride
1
anthracenes2009200915.0low000100
opipramol hydrochloride
1
2009200915.0low000100
chelerythrine chloride
1
2009200915.0low000100
tosyllysine chloromethyl ketone
1
2009200915.0low000100
5-(n-methyl-n-isobutyl)amiloride
1
2009200915.0low000100
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride
1
hydrochlorideEC 2.7.11.13 (protein kinase C) inhibitor2009200915.0high000100
amperozide hydrochloride
1
hydrochlorideanxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist		2009200915.0low000100
pyrrolidine dithiocarbamic acid
1
2009200915.0medium000100
p-Aminobenzamidine dihydrochloride
1
organic molecular entity2009200915.0high000100
carbetapentane citrate
1
carbonyl compound2009200915.0low000100
phentolamine mesylate
1
2009200915.0low000100
mephentermine
1
2-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite		2009200915.0low000100
oxybutynin hydrochloride
1
hydrochloride2009200915.0low000100
prilocaine hydrochloride
1
hydrochloridelocal anaesthetic2009200915.0low000100
brexanolone
1
3-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative		2009200915.0low000100
6-(4-nitrobenzylthio)guanosine
1
2009200915.0low000100
zpck
1
2009200915.0low000100
tetrahydrodeoxycorticosterone
1
21-hydroxy steroid2009200915.0low000100
cp-55,940
1
2009200915.0low000100
vanoxerine
1
hydrochloridedopamine uptake inhibitor2009200915.0low000100
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole
1
ether;
imidazoles;
monomethoxybenzene		TRP channel blocker2009200915.0low000100
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
1
beta-carbolines2009200915.0low000100
u 69593
1
monocarboxylic acid amide;
N-alkylpyrrolidine;
organic heterobicyclic compound;
oxaspiro compound		anti-inflammatory agent;
diuretic;
kappa-opioid receptor agonist		2009200915.0low000100
u 78517f
1
2009200915.0low000100
cv 3988
1
2009200915.0low000100
beta-carboline-3-carboxylic acid methyl ester
1
beta-carbolines2009200915.0low000100
methoctramine
1
hydrochloridemuscarinic antagonist2009200915.0low000100
betaxolol hydrochloride
1
hydrochlorideantihypertensive agent;
beta-adrenergic antagonist		2009200915.0low000100
1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine
1
hydrobromideserotonergic antagonist2009200915.0medium000100
parthenolide
1
germacranolide2009200915.0low000100
3',4'-dichlorobenzamil
1
guanidines;
pyrazines		2009200915.0low000100
gr 113808
1
indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist2009200915.0low000100
gallopamil hydrochloride
1
2009200915.0low000100
buthionine sulfoximine
1
2-amino-4-(S-butylsulfonimidoyl)butanoic acidEC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer		2009200915.0low000100
sb 204070a
1
2009200915.0low000100
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine
1
(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist		2009200915.0low000100
san 58035
1
2009200915.0low000100
mk 912
1
2009200915.0low000100
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide
1
diarylmethane2009200915.0low000100
sk&f 86466
1
benzazepine2009200915.0low000100
e 64
1
dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor		2009200915.0low000100
w 7
1
2009200915.0medium000100
pre 084
1
morpholines2009200915.0low000100
5-fluorowillardiine
1
L-alanine derivative;
non-proteinogenic L-alpha-amino acid;
organofluorine compound		AMPA receptor agonist2013201311.0low000010
methotrexate
1
dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent		2009200915.0low000100
1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol
1
2009200915.0low000100
ly 293558
1
2013201311.0low000010
sr 2640
1
quinolines2009200915.0low000100
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
1
phenylindole2009200915.0low000100
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine
1
2009200915.0low000100
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine
1
2009200915.0low000100
l 741626
1
piperidines2009200915.0low000100
nisoxetine hydrochloride
1
2009200915.0low000100
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomer
1
2009200915.0low000100
nsc-141549
1
2009200915.0low000100
idazoxan hydrochloride
1
2009200915.0low000100
cyc 202
1
2,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		2009200915.0low000100
urapidil monohydrochloride
1
2009200915.0low000100
aminopterin
1
dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen		2009200915.0low000100
varenicline
1
2013201311.0low000010
abt 980
1
2009200915.0low000100
sk&f 75670
1
2009200915.0low000100
nbi 27914
1
dialkylarylamine;
tertiary amino compound		2009200915.0low000100
sb 216763
1
indoles;
maleimides		2009200915.0low000100
dizocilpine
1
secondary amino compound;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist		2009200915.0low000100
memantine hydrochloride
1
hydrochlorideantidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist		2009200915.0low000100
pongidae
1
2009200915.0medium000100
sb 205384
1
thienopyridine2009200915.0low000100
hydrastine
1
isoquinolinesmetabolite2009200915.0low000100
bms204352
1
2013201311.0low000010
senicapoc
1
2013201311.0low000010
lacosamide
1
N-acyl-amino acid2013201311.0low000010
vincristine sulfate
1
organic sulfate saltantineoplastic agent;
geroprotector		2009200915.0low000100
nsc 95397
1
1,4-naphthoquinones2009200915.0low000100
wortmannin
1
acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent		2009200915.0low000100
ouabain
1
11alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite		2009200915.0low000100
cortodoxone
1
deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite		2009200915.0low000100
amiodarone hydrochloride
1
aromatic ketone2009200915.0low000100
dicyclomine hydrochloride
1
hydrochlorideantispasmodic drug;
muscarinic antagonist		2009200915.0low000100
nortriptyline hydrochloride
1
organic tricyclic compoundgeroprotector2009200915.0low000100
hydroxylamine hydrochloride
1
organic molecular entity2009200915.0high000100
sb 228357
1
indolyl carboxylic acid2009200915.0medium000100
actinonin
1
2009200915.0low000100
vinpocetine
1
alkaloidgeroprotector2009200915.0low000100
dihydroergocristine monomesylate
1
methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent		2009200915.0low000100
tretinoin
1
retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule		2009200915.0low000100
resveratrol
1
resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger		2009200915.0low000100
thapsigargin
1
butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor		2009200915.0low000100
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
1
carbotetracyclic compound;
polyphenol		estrogen receptor agonist;
estrogen receptor antagonist;
geroprotector;
neuroprotective agent		2009200915.0low000100
6-bromoindirubin-3'-oxime
1
2009200915.0low000100
h 89
1
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide2009200915.0low000100
melphalan
1
L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		2009200915.0low000100
isoliquiritigenin
1
chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist		2009200915.0low000100
cardamonin
1
chalcones2010201014.0low000100
gw9662
1
benzamides2009200915.0low000100
calmidazolium
1
organic chloride saltapoptosis inducer;
calmodulin antagonist		2009200915.0low000100
tropisetron hydrochloride
1
2009200915.0medium000100
quinidine sulfate
1
2009200915.0medium000100
r 59949
1
diarylmethane2009200915.0low000100
n(6)-cyclopentyladenosine
1
2009200915.0low000100
sb 366791
1
2009200915.0low000100
ag-213
1
2009200915.0low000100
3,3',4,5'-tetrahydroxystilbene
1
catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor		2009200915.0low000100
bemesetron
1
2009200915.0low000100
4-fluorophenyl-L-alanine
1
4-fluorophenylalanine;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid		2009200915.0low000100
phenylthiazolylthiourea
1
2009200915.0low000100
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)
1
benzimidazoles2009200915.0low000100
cotinine
1
N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite		2009200915.0low000100
hc 030031
1
2013201311.0low000010
cinnarizine
1
diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist		2009200915.0low000100
tg 003
1
2009200915.0low000100
(1R,2S)-tranylcypromine hydrochloride
1
hydrochloride2009200915.0low000100
tacrine hydrochloride
1
2009200915.0low000100
4-bromotetramisole, oxalate (1:1), salt(s)-isomer
1
2009200915.0medium000100
3-hydroxybenzylhydrazine hydrochloride
1
2009200915.0high000100
1-(3-chlorophenyl)biguanide hydrochloride
1
2009200915.0medium000100
capsazepine
1
benzazepine;
catechols;
monochlorobenzenes;
thioureas		capsaicin receptor antagonist2009200915.0low000100
diphenyleneiodium chloride
1
organic chloride saltEC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
G-protein-coupled receptor agonist		2009200915.0low000100
tamoxifen citrate
1
citrate saltangiogenesis inhibitor;
anticoronaviral agent		2009200915.0low000100
eskazine
1
2009200915.0low000100
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene
1
C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector		2009200915.0low000100
u 0126
1
aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent		2009200915.0low000100
4-diphenylacetoxy-n-methylpiperidine methiodide
1
iodide salt;
quaternary ammonium salt		cholinergic antagonist;
muscarinic antagonist		2009200915.0low000100
quinine
1
cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic		2009200915.0low000100
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamide
1
2009200915.0low000100
bp 897
1
naphthalenecarboxamide2009200915.0low000100
trequinsin hydrochloride
1
2009200915.0low000100
benzatropine methanesulfonate
1
2009200915.0medium000100
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea
1
1,2-thiazoles;
indoles;
ureas		receptor modulator;
serotonergic antagonist		2009200915.0low000100
gw 7647
1
aryl sulfide;
monocarboxylic acid;
ureas		PPARalpha agonist2009200915.0low000100
ro 41-0960
1
2009200915.0low000100
rn 1734
1
2013201311.0low000010
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide
1
2009200915.0low000100
l 663536
1
aryl sulfide;
indoles;
monocarboxylic acid;
monochlorobenzenes		antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
leukotriene antagonist		2009200915.0low000100
brl 15572
1
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist		2009200915.0low000100
mrs 1523
1
2009200915.0low000100
fg 9041
1
quinoxaline derivative2009200915.0low000100
sb 415286
1
C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent		2009200915.0low000100
dm 235
1
2009200915.0low000100
jhw 015
1
indolecarboxamide2009200915.0low000100
bw 723c86
1
tryptamines2009200915.0low000100
sc 560
1
aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug		2009200915.0low000100
le 300
1
indoles2009200915.0low000100
ly 367265
1
dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor		2009200915.0low000100
cgp 7930
1
alkylbenzene2009200915.0low000100
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole
1
phenols;
pyrazoles		estrogen receptor agonist2009200915.0low000100
sib 1757
1
2009200915.0low000100
apigenin
1
trihydroxyflavoneantineoplastic agent;
metabolite		2009200915.0low000100
daphnetin
1
hydroxycoumarin2009200915.0low000100
pulmicort
1
11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen		2009200915.0low000100
timolol maleate
1
maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist		2009200915.0low000100
brompheniramine maleate
1
maleate saltanti-allergic agent2009200915.0low000100
chlorpheniramine maleate
1
organic molecular entity2009200915.0low000100
clemastine fumarate
1
fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist		2009200915.0low000100
methylergonovine maleate
1
ergoline alkaloidgeroprotector2009200915.0medium000100
astaxanthine
1
carotenol;
carotenone		animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite		2009200915.0low000100
harman
1
harmala alkaloid;
indole alkaloid fundamental parent;
indole alkaloid		anti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite		2009200915.0low000100
myricetin
1
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		2009200915.0low000100
caffeic acid phenethyl ester
1
alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent		2009200915.0low000100
rottlerin
1
aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite		2009200915.0low000100
n-oleoyldopamine
1
catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		TRPV1 agonist2009200915.0low000100
pheniramine maleate
1
organic molecular entity2009200915.0low000100
tranilast
1
amidobenzoic acid;
cinnamamides;
dimethoxybenzene;
secondary carboxamide		anti-allergic agent;
anti-asthmatic drug;
antineoplastic agent;
aryl hydrocarbon receptor agonist;
calcium channel blocker;
hepatoprotective agent;
nephroprotective agent		2009200915.0low000100
trimipramine maleate
1
maleate saltantidepressant2009200915.0low000100
isotretinoin
1
retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent		2009200915.0low000100
xylometazoline hydrochloride
1
2009200915.0low000100
flunarizine hydrochloride
1
diarylmethane2009200915.0low000100
ketotifen fumarate
1
organoammonium saltanti-asthmatic drug;
H1-receptor antagonist		2009200915.0low000100
cis-flupenthixol dihydrochloride
1
hydrochloridegeroprotector2009200915.0medium000100
n-arachidonylglycine
1
fatty amide;
N-acylglycine		2009200915.0low000100
n-oleoylethanolamine
1
endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist		2009200915.0low000100
cyclosporine
1
homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite		2009200915.0low000100
phenoxybenzamine hydrochloride
1
organic molecular entity2009200915.0low000100
mepyramine maleate
1
2009200915.0low000100
brefeldin a
1
macrolide antibioticPenicillium metabolite2009200915.0low000100
fenretinide
1
monocarboxylic acid amide;
retinoid		antineoplastic agent;
antioxidant		2009200915.0low000100
su 9516
1
2009200915.0low000100
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
1
benzoic acids;
naphthalenes;
retinoid		antineoplastic agent;
retinoic acid receptor agonist;
teratogenic agent		2009200915.0low000100
l 655,708
2
2009201313.0low000110
ml 10302
1
2009200915.0low000100
sb 200646a
1
2009200915.0high000100
su 6656
1
2009200915.0low000100
ag 538
1
2009200915.0low000100
tyrphostin ag 555
1
2009200915.0low000100
tyrphostin b44
1
2009200915.0low000100
ag-490
1
catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor		2009200915.0low000100
ag 112
1
2009200915.0low000100
ag 183
1
2009200915.0low000100
semaxinib
1
olefinic compound;
oxindoles;
pyrroles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist		2009200915.0low000100
8-(3-chlorostyryl)caffeine
1
monochlorobenzenes;
trimethylxanthine		adenosine A2A receptor antagonist;
EC 1.4.3.4 (monoamine oxidase) inhibitor		2009200915.0low000100
bay 11-7085
1
benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor		2009200915.0low000100
bw b70c
1
aromatic ether;
hydroxamic acid;
organofluorine compound;
ureas		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor2009200915.0low000100
nomifensine maleate
1
2009200915.0low000100
nalbuphine hydrochloride
1
hydrochloride2009200915.0low000100
vinblastine sulfate
1
2009200915.0low000100
dextromethorphan hydrobromide
1
hydrate;
hydrobromide		2009200915.0low000100
s-trans,trans-farnesylthiosalicylic acid
1
sesquiterpenoid2009200915.0low000100
naltrexone hydrochloride
1
hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist		2009200915.0low000100
guanabenz acetate
1
dichlorobenzenegeroprotector2009200915.0low000100
nylidrin hydrochloride
1
alkylbenzene2009200915.0low000100
triprolidine hydrochloride anhydrous
1
hydrochlorideH1-receptor antagonist2009200915.0low000100
quipazine maleate
1
2009200915.0low000100
tulobuterol hydrochloride
1
organic molecular entity2009200915.0low000100
hp 029
1
2009200915.0low000100
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one
1
naphthalenes2009200915.0low000100
nf 449
1
2009200915.0medium000100
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine
1
2009200915.0low000100
homatropine hydrobromide, (endo-(+-)-isomer)
1
2009200915.0low000100
dizocilpine maleate
1
maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist		2009200915.0low000100
mg 624
1
2009200915.0low000100
flupirtine
1
2009200915.0low000100
zimelidine hydrochloride
1
2009200915.0high000100
pregna-4,17-diene-3,16-dione, (17z)-isomer
1
2009200915.0low000100
su 4312
1
2009200915.0low000100
gw 1929
1
benzophenones2009200915.0low000100
protriptyline hydrochloride
1
hydrochlorideantidepressant2009200915.0low000100
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamide
1
2009200915.0low000100
b 43
1
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		2009200915.0low000100
2-(3,3-diphenylpropylamino)acetamide
1
diarylmethane2009200915.0low000100
l 162313
1
2009200915.0low000100
sb 222200
1
quinolines2009200915.0low000100
dantrolene sodium
1
2009200915.0low000100
cr 2945
1
2009200915.0low000100
sb 218795
1
quinolines2009200915.0low000100
5-ia-85380
1
aromatic ether2013201311.0medium000010
epinephrine bitartrate
1
2009200915.0low000100
bicuculline methobromide
1
2009200915.0low000100
butaclamol hydrochloride
1
2009200915.0low000100
a 38503
1
2009200915.0low000100
bisoprolol, fumarate (1:1) salt
1
2009200915.0medium000100
cv 1808
1
purine nucleoside2009200915.0low000100
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride
1
2009200915.0medium000100
mrk 016
1
2013201311.0low000010
fluvoxamine maleate
1
(trifluoromethyl)benzenes2009200915.0low000100
naloxone benzoylhydrazone
1
2009200915.0low000100
2-methyl-6-(phenylethynyl)pyridine hydrochloride
1
hydrochlorideanxiolytic drug;
metabotropic glutamate receptor antagonist		2009200915.0low000100
(R)-fluoxetine hydrochloride
1
hydrochlorideantidepressant;
serotonin uptake inhibitor		2009200915.0medium000100
ro 8-4304
1
2009200915.0low000100
ispronicline
1
2013201311.0low000010
3-morpholino-sydnonimine monohydrochloride
1
2009200915.0low000100
t 1032
1
2009200915.0low000100
(S)-fluoxetine hydrochloride
1
hydrochlorideantidepressant;
serotonin uptake inhibitor		2009200915.0medium000100
sr 59230a
1
2009200915.0low000100
u 74389g
1
2009200915.0medium000100
1-(2-methoxyphenyl)piperazine hydrochloride
1
2009200915.0low000100
l 838,417
1
2013201311.0low000010
sb 203186
1
2009200915.0medium000100
noscapine hydrochloride
1
2009200915.0medium000100
a 77636
1
hydrochlorideantiparkinson drug;
dopamine agonist		2009200915.0medium000100
cgp 20712a
1
2009200915.0low000100
levodopa methyl ester hydrochloride
1
2009200915.0low000100
a-317567
1
2013201311.0low000010
lu 19005
1
2009200915.0medium000100
benoxathian hydrochloride
1
2009200915.0medium000100
((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1h-inden-5-yl)oxy)acetic acid, (+)-isomer
1
2009200915.0low000100
tetrodotoxin
1
2013201311.0low000010
calpain inhibitor iii
1
2009200915.0low000100
GR 127935 hydrochloride
1
hydrochlorideserotonergic antagonist2009200915.0medium000100
mrs 1845
1
2009200915.0low000100
1-aminocyclopropane-1-carboxylic acid hydrochloride
1
2009200915.0medium000100
alaproclate hydrochloride
1
2009200915.0medium000100
ubenimex
1
peptide2009200915.0low000100
dsp 4 hydrochloride
1
2009200915.0medium000100
calcimycin
1
benzoxazole2009200915.0low000100
(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride
1
hydrochloridealpha-adrenergic antagonist2009200915.0low000100
2-cyclooctyl-2-hydroxyethylamine hydrochloride
1
2009200915.0medium000100
cirazoline monohydrochloride
1
2009200915.0medium000100
adtn
1
2009200915.0medium000100
apocodeine hydrochloride, (r)-isomer
1
2009200915.0medium000100
2-hydroxyapomorphine, (r)-isomer
1
2009200915.0high000100
lilly 78335
1
2009200915.0medium000100
efaroxan hydrochloride
1
2009200915.0low000100
fenoldopam hydrobromide
1
2009200915.0low000100
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
1
hydrochloridedopamine uptake inhibitor2009200915.0medium000100
7-hydroxy-2-n,n-dipropylaminotetralin hydrobromide
1
2009200915.0low000100
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (r)-isomer,
1
organic molecular entity2009200915.0low000100
1-(2-(4-(4-fluoro-benzoyl)-piperidin-1-yl)-ethyl)-3,3-dimethyl-1,2-dihydro-indol-2-one
1
hydrochloridereceptor modulator;
serotonergic antagonist		2009200915.0low000100
4-iodoclonidine
1
2009200915.0medium000100
alpha-methyltyrosine methyl ester, monohydrochloride
1
2009200915.0medium000100
octoclothepine maleate
1
2009200915.0low000100
2-(n-phenethyl-n-propyl)amino-5-hydroxytetralin hydrochloride
1
2009200915.0low000100
du 24565
1
2009200915.0high000100
2-methoxyidazoxan hydrochloride
1
2009200915.0medium000100
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide
1
hydrobromidedopamine agonist;
prodrug		2009200915.0medium000100
ro 25-6981
1
2009200915.0medium000100
sk&f 77434
1
hydrobromidedopamine agonist;
prodrug		2009200915.0low000100
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea
1
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		2009200915.0high000100
demethylcantharidin
1
2009200915.0low000100
atropine sulfate
1
2009200915.0low000100
win 62577
1
2009200915.0medium000100
quinine sulfate
1
hydrate2009200915.0low000100
quercetin
1
2009200915.0low000100
rv 538, (r-(r*,r*))-isomer
1
2009200915.0medium000100
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (1s-cis)-isomer
1
2009200915.0medium000100
taurocholic acid, monosodium salt
1
bile salt2009200915.0medium000100
fusidate sodium
1
2009200915.0medium000100
cefazolin sodium
1
organic sodium salt2009200915.0low000100
cortisol succinate, sodium salt
1
organic molecular entity2009200915.0low000100
piroxicam
1
benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug		2009200915.0low000100
hispidin
1
2-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite		2009200915.0low000100
minocycline hydrochloride
1
2009200915.0low000100
demeclocycline hydrochloride
1
2009200915.0low000100
clozapine
1
benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic		2009200915.0low000100
zaprinast
1
triazolopyrimidines2009200915.0low000100
8-bromocyclic gmp, sodium salt
1
organic sodium saltmuscle relaxant;
protein kinase G agonist		2009200915.0medium000100
ag-879
1
2009200915.0low000100
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
allantoin
1
imidazolidine-2,4-dione;
ureas		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary		201820186.0low000010
clofazimine
2
monochlorobenzenes;
phenazines		dye;
leprostatic drug;
non-steroidal anti-inflammatory drug		2012201311.5low000020
metformin
1
guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic		201820186.0low000010
ficusin
20
psoralensplant metabolite2005202210.3low0004133
sirolimus
1
antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		201820186.0low000010
correolide
1
hydroxy steroid2011201113.0low000010
endothelin-1
1
2008200816.0low000100
transforming growth factor beta
1
201820186.0low000010
margatoxin
3
2011201412.0low000030
rifampin
1
cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor		201820186.0low000010
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Acute Confusional Senile Dementia0
1
201820186.0low000010
Acute Coronary Syndrome0
1
2012201212.0low000010
Aging0
1
201820186.0low000010
Allergic Contact Dermatitis0
1
2013201311.0low000010
Alloxan Diabetes0
1
2011201113.0low000010
Alzheimer Disease0
1
201820186.0low000010
Anterior Optic Neuritis0
1
2008200816.0low000100
Apoplexy0
1
202120213.0low000001
Autoimmune Disease0
1
2008200816.0low000100
Autoimmune Diseases0
1
2008200816.0low000100
B-Cell Chronic Lymphocytic Leukemia0
1
2013201311.0low000010
B16 Melanoma0
1
2012201212.0low000010
Break-Bone Fever0
1
202120213.0low000001
Bright Disease0
1
2010201014.0low000100
Cerebral Infarction, Middle Cerebral Artery0
1
202120213.0low000001
Colitis0
1
201920195.0low000010
Congenital Zika Syndrome0
2
202020213.5low000011
Contact Dermatitis0
1
201920195.0low000010
Dengue0
1
202120213.0low000001
Dermatitis, Allergic Contact0
1
2013201311.0low000010
Dermatitis, Contact0
1
201920195.0low000010
Dermatitis, Contact, Phototoxic0
1
2005200519.0low000100
Disease Models, Animal0
5
201320215.8low000041
Extravascular Hemolysis0
1
2005200519.0low000100
Glomerulonephritis0
1
2010201014.0low000100
Hemolysis0
1
2005200519.0low000100
Hepatitis C0
1
202120213.0low000001
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted0
1
202120213.0low000001
Hyperglycemia0
1
2011201113.0low000010
Hyperglycemia, Postprandial0
1
2011201113.0low000010
Hyperplasia0
1
2011201113.0low000010
Infarction, Middle Cerebral Artery0
1
202120213.0low000001
Infections, Respirovirus0
1
202120213.0low000001
Inflammation0
1
2008200816.0low000100
Innate Inflammatory Response0
1
2008200816.0low000100
Insulin Resistance0
1
2011201113.0low000010
Insulin Sensitivity0
1
2011201113.0low000010
Itching0
1
201920195.0low000010
Leukemia, Lymphocytic, Chronic, B-Cell0
1
2013201311.0low000010
Malaria, Falciparum0
1
2014201410.0low000010
Obesity0
1
2011201113.0low000010
Optic Neuritis0
1
2008200816.0low000100
Plasmodium falciparum Malaria0
1
2014201410.0low000010
Pruritus0
1
201920195.0low000010
Stroke0
1
202120213.0low000001
Zika Virus Infection0
2
202020213.5low000011

Safety/Toxicity (3)

ArticleYear
Identification of phase-I metabolites and chronic toxicity study of the Kv1.3 blocker PAP-1 (5-(4-phenoxybutoxy)psoralen) in the rat.
Xenobiotica; the fate of foreign compounds in biological systems, , Volume: 41, Issue:3		2011
Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques.
Experimental biology and medicine (Maywood, N.J.), , Volume: 232, Issue:10		2007
5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: mechanistic studies on phototoxicity.
Die Pharmazie, , Volume: 60, Issue:3		2005

Pharmacokinetics (1)

ArticleYear
Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques.
Experimental biology and medicine (Maywood, N.J.), , Volume: 232, Issue:10		2007

Dosage (1)

ArticleYear
Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques.
Experimental biology and medicine (Maywood, N.J.), , Volume: 232, Issue:10		2007