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metoprolol and Hyperglycemia

metoprolol has been researched along with Hyperglycemia in 7 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
" Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension."9.08Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996)
"Although prior literature suggests that metoprolol may worsen glucose control compared to carvedilol, whether this has clinical relevance among older adults with diabetes and heart failure (HF) remains an open question."8.02Risk of clinically relevant hyperglycemia with metoprolol compared to carvedilol in older adults with heart failure and diabetes. ( Dave, CV; Dejanovic, I; Gerhard, T; Horton, DB; Kobylarz, FA; Nyandege, A; Setoguchi, S; Strom, BL; Tseng, CL, 2021)
"Diazepam-elicited hyperglycemia in mice was inhibited by adrenalectomy and the catecholamine synthesis inhibitor alpha-methyl-p-tyrosine, although it was unaffected by pretreatment with the corticosterone synthesis inhibitor dexamethasone."7.70Involvement of adrenaline in diazepam-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 2000)
"Glycosuria, hyperglycemia, and nephrotic-range proteinuria developed in a 68-year-old patient after clonidine was added to a stable antihypertensive regimen, which included metoprolol, of three years' duration."7.67Nephrotic-range proteinuria and hyperglycemia associated with clonidine therapy. ( Josselson, J; Sadler, JH, 1986)
"The Glycemic Effect in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) trial compared the metabolic effects of two beta-blockers in people with type 2 diabetes and hypertension treated with renin-angiotensin system (RAS) blockade and found differences in metabolic outcomes."5.12beta-blocker use and diabetes symptom score: results from the GEMINI study. ( Anderson, KM; Bakris, GL; Bell, DS; Dalal, MR; Fonseca, V; Iyengar, M; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Phillips, RA; Raskin, P; Wright, JT, 2007)
" Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension."5.08Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996)
"Although prior literature suggests that metoprolol may worsen glucose control compared to carvedilol, whether this has clinical relevance among older adults with diabetes and heart failure (HF) remains an open question."4.02Risk of clinically relevant hyperglycemia with metoprolol compared to carvedilol in older adults with heart failure and diabetes. ( Dave, CV; Dejanovic, I; Gerhard, T; Horton, DB; Kobylarz, FA; Nyandege, A; Setoguchi, S; Strom, BL; Tseng, CL, 2021)
"Diazepam-elicited hyperglycemia in mice was inhibited by adrenalectomy and the catecholamine synthesis inhibitor alpha-methyl-p-tyrosine, although it was unaffected by pretreatment with the corticosterone synthesis inhibitor dexamethasone."3.70Involvement of adrenaline in diazepam-induced hyperglycemia in mice. ( Noma, T; Sugimoto, Y; Yamada, J, 2000)
"Glycosuria, hyperglycemia, and nephrotic-range proteinuria developed in a 68-year-old patient after clonidine was added to a stable antihypertensive regimen, which included metoprolol, of three years' duration."3.67Nephrotic-range proteinuria and hyperglycemia associated with clonidine therapy. ( Josselson, J; Sadler, JH, 1986)
"Recognizing SIDS as part of the diagnostic criteria for BrS would help us identifying a significant number of families susceptible to develop SCD (as well as SIDS)."1.40EKG pattern of Brugada syndrome and sudden infant death syndrome--is it time to review the diagnostic criteria? Case report and review of literature. ( Dias, A; Franco, E; Hebert, K; Teresa, D, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Dave, CV1
Strom, BL1
Kobylarz, FA1
Horton, DB1
Gerhard, T1
Tseng, CL1
Dejanovic, I1
Nyandege, A1
Setoguchi, S1
Franco, E1
Dias, A1
Teresa, D1
Hebert, K1
McGill, JB1
Bakris, GL1
Fonseca, V1
Raskin, P1
Messerli, FH1
Phillips, RA1
Katholi, RE1
Wright, JT1
Iyengar, M1
Anderson, KM1
Lukas, MA1
Dalal, MR1
Bell, DS1
Laakso, M1
Karjalainen, L1
Lempiäinen-Kuosa, P1
Yamada, J1
Sugimoto, Y1
Noma, T1
Lager, I1
Blohmé, G1
Smith, U1
Josselson, J1
Sadler, JH1

Trials

3 trials available for metoprolol and Hyperglycemia

ArticleYear
beta-blocker use and diabetes symptom score: results from the GEMINI study.
    Diabetes, obesity & metabolism, 2007, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Carvedilol; Cognition; Diab

2007
Effects of losartan on insulin sensitivity in hypertensive subjects.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:3

    Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Fatty Acids, Nones

1996
Effect of cardioselective and non-selective beta-blockade on the hypoglycaemic response in insulin-dependent diabetics.
    Lancet (London, England), 1979, Mar-03, Volume: 1, Issue:8114

    Topics: Adult; Blood Glucose; Blood Pressure; Bradycardia; Clinical Trials as Topic; Diabetes Mellitus; Dias

1979

Other Studies

4 other studies available for metoprolol and Hyperglycemia

ArticleYear
Risk of clinically relevant hyperglycemia with metoprolol compared to carvedilol in older adults with heart failure and diabetes.
    Pharmacoepidemiology and drug safety, 2021, Volume: 30, Issue:10

    Topics: Aged; Carvedilol; Diabetes Mellitus; Heart Failure; Humans; Hyperglycemia; Male; Medicare; Metoprolo

2021
EKG pattern of Brugada syndrome and sudden infant death syndrome--is it time to review the diagnostic criteria? Case report and review of literature.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014, Volume: 19, Issue:2

    Topics: Acidosis; Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brugada S

2014
Involvement of adrenaline in diazepam-induced hyperglycemia in mice.
    Life sciences, 2000, Feb-18, Volume: 66, Issue:13

    Topics: Adrenergic beta-Antagonists; alpha-Methyltyrosine; Animals; Blood Glucose; Diazepam; Epinephrine; Hy

2000
Nephrotic-range proteinuria and hyperglycemia associated with clonidine therapy.
    The American journal of medicine, 1986, Volume: 80, Issue:3

    Topics: Aged; Clonidine; Drug Synergism; Glycosuria; Humans; Hyperglycemia; Insulin; Male; Metoprolol; Prote

1986