leucine and Hyperglycemia

leucine has been researched along with Hyperglycemia in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199045 (61.64)18.7374
1990's12 (16.44)18.2507
2000's7 (9.59)29.6817
2010's8 (10.96)24.3611
2020's1 (1.37)2.80

Authors

AuthorsStudies
Burgner, D; Chan, SY; Chong, MF; Chong, YS; Eriksson, JG; Lee, YS; Li, LJ; Liu, M; Tint, MT; Yang, J; Yap, F; Zhang, C1
Kolahian, S; Larki, NN; Sadri, H1
Chao, T; Fan, W; Hao, L; Huang, J; Jin, Q; Li, H; Liu, R; Wu, Y; Yang, X1
Coqueiro, AY; Lima, VBS; Martins, CEC; Ribeiro, HQT; Tirapegui, J1
Arapostathi, C; Argyrakopoulou, G; Eleftheriadou, I; Katsilambros, N; Kokkinos, A; Kontrafouri, P; Kyriaki, D; Perrea, D; Revenas, C; Tentolouris, N1
Braun, S; Demmelmair, H; Hartl, WH; Jauch, KW; Koletzko, B; Kuppinger, D; Rittler, P; Vogeser, M1
Brum, PC; Chaves, DF; da Luz, CR; Dardevet, D; de Moraes, WM; de Siqueira Filho, MA; Lancha, AH; Medeiros, A; Nicastro, H; Ramona, P; Zanchi, NE1
Bassil, MS; Gougeon, R1
Campbell, WW; Evans, WJ; Kirwan, JP; Krishnan, RK; Kullman, EL; Yarasheski, KE1
Awazu, M; Fujita, H; Hida, M; Ishikura, K; Omori, S1
BONESSI, JV; DANOWSKI, TS; MOSES, C1
BOUMAN, PR1
LEVINE, R; MAHLER, R1
FOA, PP1
CONN, JW; FAJANS, SS; FLOYD, JC; KNOPF, RF1
Al-Saleh, E; Al-Shammari, M; Harouny, AK; Nandakumaran, M1
Adiels, M; Borén, J; Caslake, MJ; Olofsson, SO; Packard, C; Soro, A; Stewart, P; Taskinen, MR; Wennberg, B; Westerbacka, J1
de Roos, AL; Koopman, R; Manders, RJ; Meex, RC; Praet, SF; Saris, WH; van Loon, LJ; Wagenmakers, AJ1
Barazzoni, R; Biolo, G; Dal Mas, V; De Cicco, M; Fantin, D; Guarnieri, G; Iapichino, G; Lorenzon, S; Paroni, R; Zanetti, M1
Christophe, J; Czyzyk, A; Ooms, HA; Wodon, C1
Logothetopoulos, J; Valiquette, N1
Besch, W; Wilke, B1
Bier, DM; Matthews, DE; Robert, JJ; Young, VR; Zhao, XH1
Jain, K; Logothetopoulos, J2
Asano, G; Shimizu, Y; Win, T1
Beaufrere, B; Campbell, PJ; Gerich, JE; Gottesman, IS; Haymond, MW; Heiling, VJ; Tsalikian, E1
Abumrad, NN; Flakoll, PJ; Hill, JO; May, MM; Rice, DE1
Abumrad, NN; Flakoll, PJ; Hill, JO1
Angermaier, A; Buchfelder, M; Fahlbusch, R; Georgieff, M; Reinartz, G1
Clavo, AC; Torizuka, T; Wahl, RL1
Bedford, D; Caslake, M; Malmström, R; Packard, CJ; Shepherd, J; Stewart, P; Taskinen, MR; Yki-Järvinen, H1
Boland, O; Matthews, DR1
Bernard, C; Berthault, MF; Ktorza, A; Magnan, C; Pénicaud, L; Portha, B; Pralong, WF; Saulnier, C; Thibault, C1
Agell, N; Alvarez, B; Argilś, JM; Busquets, S; Lpez-Soriano, FJ; Rodríguez, T1
Anderson, SM; Hay, WW; Thureen, PJ1
Bhatnagar, A; Chandra, D; Christensen, BN; Ramana, KV; Srivastava, SK; Wang, L1
Porath, U; Schreier, K1
Gylfe, E; Sehlin, J1
Fex, G; Lernmark, A1
Buéno, L; Ruckebusch, M1
Ruderman, NB1
Gunnarsson, R1
Bleecker, S; Caster, WO1
Amatruda, JM; Barnard, RR; Statt, M; Welle, S1
Darmaun, D; Koziet, J; Robert, JJ; Rongier, M1
Bard, H; Fouron, JC1
Takao, F1
Askari, A; Birkhahn, RH; Thomford, NR1
Beaufrere, B; Bier, DM; Desjeux, JF; Koziet, J; Lestradet, H; Robert, JJ; Young, VR1
Christians, J; Hasselblatt, A; Panten, U; Poser, W; von Kriegstein, E1
Gates, RJ; Hunt, MI; Lazarus, NR1
Mashimo, K; Nakagawa, M1
Conn, JW; Fajans, SS; Floyd, JC; Harrison, TS; Knopf, RF; Thiffault, CA1
Brauman, H; Corvilain, J; Telerman-Toppet, N1
Hellman, B; Sehlin, J; Täljedal, IB3
Lernmark, A1
Briel, G; Gylfe, E; Hellman, B; Neuhoff, V1
Sehlin, J1
Duprey, J; Lubetzki, J1
Paulsen, EP1
Idahl, LA; Täljedal, IB1
Hellerström, C; Schmidt, FH; Stork, H; Westman, S1
Hellman, B; Sehlin, J; Täljedal, I1
Steuer, W1
Berger, S; Green, OC1
Ciofalo, LM; Roberts, ME1
Junod, A; Lambert, AE; Letarte, J; Stauffacher, W1
Boutry, M; Christophe, J; Furnelle, J; Winand, J1
Hipólito-Reis, C; Sobrinho-Simões, M1
Butterfield, WJ; Hicks, BH; Mallinson, CN; Whichelow, MJ1

Reviews

6 review(s) available for leucine and Hyperglycemia

ArticleYear
Muscle protein anabolism in type 2 diabetes.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Aged; Aging; Amino Acids, Branched-Chain; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hyperglycemia; Insulin; Insulin Resistance; Leucine; Male; Motor Activity; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Obesity; Protein Biosynthesis; Sarcopenia

2013
[POSSIBILITIES AND LIMITATIONS IN THE DETERMINATION OF INSULIN IN BLOOD IN THE DIAGNOSIS OF HYPERINSULINISM].
    Maandschrift voor kindergeneeskunde, 1963, Volume: 31

    Topics: Adenoma, Islet Cell; Blood; Diagnosis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide

1963
PRODUCTION, SECRETION, AND AVAILABILITY OF INSULIN.
    Annual review of medicine, 1964, Volume: 15

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Chemical Phenomena; Chemistry; Growth Hormone; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Antibodies; Leucine; Metabolism; Tolbutamide

1964
EXPERIMENTAL DIABETES AND THE MODE OF ACTION OF THE SULFONYLUREAS. WITH SOME SPECULATIONS ON THE PREVENTION OF DIABETES.
    Bulletin - Sinai Hospital of Detroit, 1964, Volume: 12

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cortisone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids; Fluoroacetates; Genetics, Medical; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Leucine; Pharmacology; Pregnancy; Prolactin; Rats; Research; Sulfonylurea Compounds; Tolbutamide

1964
[Congenital metabolic acidosis in the postnatal period].
    Deutsche medizinische Wochenschrift (1946), 1978, Jun-02, Volume: 103, Issue:22

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Fructose-1,6-Diphosphatase Deficiency; Glutarates; Glycogen Storage Disease Type I; Humans; Hyperglycemia; Infant, Newborn; Isoleucine; Ketosis; Lactates; Leucine; Leukoencephalitis, Acute Hemorrhagic; Methylmalonic Acid; Propionates; Syndrome; Thiamine; Valerates; Valine

1978
Muscle amino acid metabolism and gluconeogenesis.
    Annual review of medicine, 1975, Volume: 26

    Topics: Adaptation, Physiological; Alanine; Amino Acids; Aminoacylation; Animals; Fasting; Forearm; Gluconeogenesis; Glucose; Glutamine; Homeostasis; Humans; Hyperglycemia; Hypoglycemia; Kidney Failure, Chronic; Leucine; Muscle Proteins; Muscles; Nitrogen; Pericardium; Rats; Starvation

1975

Trials

7 trial(s) available for leucine and Hyperglycemia

ArticleYear
The Effect of the Oral Administration of Leucine on Endothelial Function, Glucose and Insulin Concentrations in Healthy Subjects.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2019, Volume: 127, Issue:8

    Topics: Adult; Blood Glucose; Cross-Over Studies; Endothelium, Vascular; Female; Humans; Hyperglycemia; Insulin; Leucine; Male

2019
Albumin synthesis rates are not responsive to hyperglycemic hyperinsulinemia in postoperative patients.
    JPEN. Journal of parenteral and enteral nutrition, 2011, Volume: 35, Issue:3

    Topics: Abdomen; Aged; Carbon Isotopes; Case-Control Studies; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Middle Aged; Postoperative Complications; Serum Albumin

2011
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:8

    Topics: Adult; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, VLDL; Deuterium; Diabetes Mellitus, Type 2; Dyslipidemias; Glycerol; Humans; Hyperglycemia; Insulin Resistance; Leucine; Male; Triglycerides

2005
Protein hydrolysate/leucine co-ingestion reduces the prevalence of hyperglycemia in type 2 diabetic patients.
    Diabetes care, 2006, Volume: 29, Issue:12

    Topics: Administration, Oral; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Leucine; Prevalence; Protein Hydrolysates; Reference Values

2006
Treating hyperglycemia improves skeletal muscle protein metabolism in cancer patients after major surgery.
    Critical care medicine, 2008, Volume: 36, Issue:6

    Topics: Abdominal Neoplasms; Amino Acids; Arginine; Blood Glucose; Cancer Care Facilities; Combined Modality Therapy; Critical Care; Cross-Over Studies; Energy Metabolism; Female; Glutamine; Humans; Hyperglycemia; Insulin; Insulin Resistance; Leucine; Middle Aged; Muscle Proteins; Muscle, Skeletal; Overweight; Parenteral Nutrition, Total; Phenylalanine; Postoperative Complications; Radiotherapy, Adjuvant

2008
Pre- and postoperative investigations of hepatic glucose production and leucine turnover in Cushing's disease utilizing stable isotope techniques.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1995, Volume: 27, Issue:9

    Topics: Adult; Blood Glucose; Cushing Syndrome; Female; Humans; Hydrocortisone; Hyperglycemia; Leucine; Liver; Male; Microsurgery; Middle Aged; Muscles; Pituitary Gland; Postoperative Period

1995
The stimulation of insulin secretion in non-insulin-dependent diabetic patients by amino acids and gliclazide in the basal and hyperglycemic state.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1

    Topics: Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Gliclazide; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Time Factors

1997

Other Studies

60 other study(ies) available for leucine and Hyperglycemia

ArticleYear
Maternal glycemic status during pregnancy and mid-childhood plasma amino acid profiles: findings from a multi-ethnic Asian birth cohort.
    BMC medicine, 2023, Nov-29, Volume: 21, Issue:1

    Topics: Birth Cohort; Body Mass Index; Cardiovascular Diseases; Child; Diabetes, Gestational; Female; Glucose; Histidine; Humans; Hyperglycemia; Isoleucine; Leucine; Pregnancy; Valine

2023
Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes.
    Biological trace element research, 2017, Volume: 180, Issue:2

    Topics: Animals; Blood Glucose; Chromium; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dietary Supplements; Glyburide; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin Resistance; Leucine; Lipids; Male; Random Allocation; Rats, Wistar; Streptozocin; Zinc

2017
Leucine Supplementation Differently Modulates Branched-Chain Amino Acid Catabolism, Mitochondrial Function and Metabolic Profiles at the Different Stage of Insulin Resistance in Rats on High-Fat Diet.
    Nutrients, 2017, Jun-02, Volume: 9, Issue:6

    Topics: Amino Acids, Branched-Chain; Animals; Caloric Restriction; Diet, High-Fat; Dietary Supplements; Hyperglycemia; Insulin Resistance; Leucine; Lipid Metabolism; Male; Mitochondria; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

2017
Leucine and resistance training improve hyperglycemia, white adipose tissue loss, and inflammatory parameters in an experimental model of type 1 diabetes.
    Nutrition and health, 2018, Volume: 24, Issue:1

    Topics: Adiponectin; Adipose Tissue, White; Adiposity; Animals; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Diabetes Mellitus, Type 1; Dietary Supplements; Gene Expression Regulation; Hyperglycemia; Inflammation Mediators; Insulin Resistance; Intra-Abdominal Fat; Leptin; Leucine; Male; Random Allocation; Rats, Wistar; Resistance Training; Weight Loss

2018
Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2012, Volume: 28, Issue:4

    Topics: Animals; Blood Glucose; Dexamethasone; Dietary Supplements; Glucose Transporter Type 4; Hyperglycemia; Insulin Resistance; Leucine; Male; Movement; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Wistar; Resistance Training; Ribosomal Protein S6 Kinases, 70-kDa

2012
Age attenuates leucine oxidation after eccentric exercise.
    International journal of sports medicine, 2013, Volume: 34, Issue:8

    Topics: Age Factors; Aged; Aging; Exercise; Exercise Test; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin Resistance; Leucine; Male; Middle Aged; Oxidation-Reduction; Time Factors; Young Adult

2013
The lack of cyclin kinase inhibitor p27(Kip1) ameliorates progression of diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Albuminuria; Animals; Blood Group Antigens; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Disease Progression; Eukaryotic Initiation Factors; Fibronectins; Glomerular Mesangium; Hyperglycemia; Leucine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphoproteins; Phosphorylation; Proliferating Cell Nuclear Antigen; Thymidine; Transforming Growth Factor beta; Tritium; Tumor Suppressor Proteins

2003
Acute tolbutamide and leucine effects in diabetes mellitus.
    Metabolism: clinical and experimental, 1962, Volume: 11

    Topics: Diabetes Mellitus; Hyperglycemia; Hypoglycemia; Leucine; Pancreatic Diseases; Phosphates; Potassium; Tolbutamide

1962
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pharmacology; Surgical Procedures, Operative; Tolbutamide

1964
Effect of hyperglycaemic load on maternal-foetal transport of L-leucine in perfused human placental lobule: in vitro study.
    Acta diabetologica, 2005, Volume: 42, Issue:1

    Topics: Area Under Curve; Biological Transport; Female; Humans; Hyperglycemia; Kinetics; Leucine; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Pregnancy in Diabetics; Tissue Culture Techniques

2005
[Hypoaminoacidemia in the dog after rapid intravenous injection of L-leucine].
    Revue francaise d'etudes cliniques et biologiques, 1967, Volume: 12, Issue:8

    Topics: Amino Acids; Animals; Biological Transport, Active; Blood Glucose; Chlorpropamide; Dogs; Glucose; Hyperglycemia; Injections, Intravenous; Insulin; Leucine

1967
Hormonal and non-hormonal protein biosynthesis in the pancreatic beta cell of the intact rat after prolonged hyperglycaemia.
    Acta endocrinologica, 1984, Volume: 107, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Cerebral Cortex; DNA; Hyperglycemia; Islets of Langerhans; Leucine; Male; Pituitary Gland, Anterior; Proinsulin; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tryptophan

1984
Characterization of beta-cell specific function of isolated pancreatic islets from hyperglycemic C57BL/KsJ-db/db mice.
    Acta biologica et medica Germanica, 1982, Volume: 41, Issue:12

    Topics: Animals; Blood Glucose; Cells, Cultured; Hyperglycemia; Hyperinsulinism; Insulin; Islets of Langerhans; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Proinsulin; Protein Precursors

1982
Glucose and insulin effects on the novo amino acid synthesis in young men: studies with stable isotope labeled alanine, glycine, leucine, and lysine.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:12

    Topics: Adult; Alanine; Amino Acids; Blood Glucose; Glucose; Glycine; Humans; Hyperglycemia; Infusions, Parenteral; Insulin; Leucine; Lysine; Male; Nitrogen

1982
In vivo incorporation of [3H[ leucine and [3H] tryptophan into proinsulin-insulin and other islet cell proteins in normoglycemic, hyperglycemic, and hypoglycemic rats.
    Diabetes, 1980, Volume: 29, Issue:10

    Topics: Animals; Autoradiography; Blood Glucose; Hyperglycemia; Insulin; Islets of Langerhans; Leucine; Male; Proinsulin; Protein Biosynthesis; Rats; Tritium; Tryptophan

1980
The efficacy of aldose reductase inhibitor, antioxidant butylated hydroxytoluene and cysteine protease inhibitor E64 on hyperglycemia-induced metabolic changes in the organ-cultured bovine lens.
    Nihon Ika Daigaku zasshi, 1994, Volume: 61, Issue:3

    Topics: Aldehyde Reductase; Animals; Butylated Hydroxytoluene; Cataract; Cattle; Culture Techniques; Cysteine Proteinase Inhibitors; Hyperglycemia; Lens, Crystalline; Leucine; Magnetic Resonance Spectroscopy

1994
Differential effects of hyperglycemia and hyperinsulinemia on leucine rate of appearance in normal humans.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1

    Topics: Adult; Blood Glucose; Female; Glucagon; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Infusion Systems; Leucine; Male; Middle Aged; Reference Values; Somatostatin

1993
The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:2

    Topics: Adult; Amino Acids; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Isoleucine; Leucine; Male; Obesity; Phenylalanine; Reference Values

1994
Acute hyperglycemia enhances proteolysis in normal man.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Adult; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Glucose; Humans; Hyperglycemia; Insulin; Isotope Labeling; Leucine; Male; Middle Aged; Oxidation-Reduction; Proteins; Radioisotope Dilution Technique; Respiration; Tritium

1993
Effect of hyperglycemia on in vitro tumor uptake of tritiated FDG, thymidine, L-methionine and L-leucine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Hyperglycemia; Leucine; Methionine; Ovarian Neoplasms; Thymidine; Tomography, Emission-Computed; Tumor Cells, Cultured

1997
Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM.
    Diabetologia, 1997, Volume: 40, Issue:4

    Topics: Apolipoproteins B; Cholesterol; Cholesterol, HDL; Deuterium; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Intravenous; Insulin; Leucine; Lipoproteins, VLDL; Liver; Male; Middle Aged; Models, Biological; Radioisotope Dilution Technique; Reference Values; Triglycerides

1997
Pancreatic beta-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement.
    Diabetes, 1998, Volume: 47, Issue:7

    Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Hyperinsulinism; Immunoenzyme Techniques; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Rats, Wistar; Regeneration

1998
Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis.
    International journal of molecular medicine, 1998, Volume: 1, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adipose Tissue; Animals; Body Weight; Diabetes Mellitus, Experimental; Female; Hydrolysis; Hyperglycemia; Insulin; Isoleucine; Kidney; Leucine; Liver; Liver Glycogen; Methylhistidines; Muscle Development; Muscle Proteins; Muscle, Skeletal; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Ubiquitins; Valine

1998
Regulation of uterine and umbilical amino acid uptakes by maternal amino acid concentrations.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Female; Gestational Age; Glucose Clamp Technique; Hyperglycemia; Insulin; Lactic Acid; Leucine; Lysine; Maternal-Fetal Exchange; Ornithine; Oxygen; Placenta; Pregnancy; Sheep; Umbilical Cord; Uterus

2000
Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:7

    Topics: Aminopeptidases; Animals; Calcium; Calpain; Cataract; Chromatography, Ion Exchange; Glucose; Glutathione; Hyperglycemia; Lens Cortex, Crystalline; Leucine; Organ Culture Techniques; Phthalimides; Protease Inhibitors; Rats; Rats, Sprague-Dawley

2002
Secretion of insulin in a perifusion system and conversion of proinsulin to insulin by pancreatic islets from hyperglycemic rats.
    Diabetes, 1977, Volume: 26, Issue:7

    Topics: Animals; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Male; Proinsulin; Rats

1977
Interactions between the metabolism of L-leucine and D-glucose in the pancreatic beta-cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:1

    Topics: Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glucose; Glutamates; Glycolysis; Hyperglycemia; Islets of Langerhans; Leucine; Mice; Mice, Obese

1976
Effects of insulin secretagogues on phospholipid metabolism in pancreatic beta-cells.
    Biochimica et biophysica acta, 1975, Apr-18, Volume: 388, Issue:1

    Topics: Animals; Arginine; Glucose; Glyburide; Hyperglycemia; Insulin; Islets of Langerhans; Leucine; Mice; Mice, Obese; Phosphates; Phosphatidylinositols; Phosphatidylserines; Phospholipids

1975
Insulin and jejunal electrical activity in dogs and sheep.
    The American journal of physiology, 1976, Volume: 230, Issue:6

    Topics: Animals; Arginine; Blood Glucose; Dogs; Fatty Acids, Volatile; Female; Gastrointestinal Motility; Glucagon; Glucose; Hyperglycemia; Insulin; Jejunum; Leucine; Male; Membrane Potentials; Milk; Sheep; Vagotomy; Vagus Nerve

1976
Function of the pancreatic B-cell during the development of hyperglycaemia in mice homozygous for the mutations "diabetes" (db) and "misty" (m).
    Diabetologia, 1975, Volume: 11, Issue:5

    Topics: Age Factors; Animals; Body Weight; Diabetes Mellitus; Female; Glucose; Hair Color; Homozygote; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Mice, Inbred C57BL; Mutation; Oxidation-Reduction; Proinsulin

1975
Hyperglycemic effect of amino compounds structurally related to caproate in rats.
    The Journal of nutrition, 1975, Volume: 105, Issue:3

    Topics: Amino Acids; Aminocaproates; Animals; Diabetes Mellitus; Glucose Tolerance Test; Glutamates; Glycosuria; Hyperglycemia; Leucine; Male; Methionine; Norleucine; Rats; Structure-Activity Relationship; Time Factors

1975
Increased protein turnover in obese women.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:9

    Topics: Abdomen; Adult; Body Mass Index; Body Weight; Female; Glucose Tolerance Test; Hip; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Leucine; Magnetic Resonance Imaging; Middle Aged; Obesity; Proteins

1992
Glutamine nitrogen kinetics in insulin-dependent diabetic humans.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Adult; Diabetes Mellitus, Type 1; Glutamine; Humans; Hyperglycemia; Insulin; Kinetics; Leucine; Male; Nitrogen

1991
The increase in fetal hemoglobin synthesis in the fetal lamb during hyperglycemic hypoxemia.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:5

    Topics: Animals; Blood Glucose; Chromatography; Erythrocytes; Fetal Hemoglobin; Hyperglycemia; Hypoxia; Leucine; Oxygen; Partial Pressure; Sheep

1988
[The effect of maternal hyperglycemia on insulin secretion by monolayer-cultured B cells of neonatal rats--a perifusion study].
    Nihon Naibunpi Gakkai zasshi, 1989, Aug-20, Volume: 65, Issue:8

    Topics: Animals; Animals, Newborn; Arginine; Cells, Cultured; Female; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Perfusion; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred Strains; Streptozocin

1989
The influence of ketosis on the metabolic response to skeletal trauma.
    The Journal of surgical research, 1988, Volume: 44, Issue:2

    Topics: Acetoacetates; Acidosis; Animals; Body Weight; Copper; Femoral Fractures; Glucose; Glycerides; Hyperglycemia; Ketone Bodies; Ketosis; Leucine; Male; Nitrogen; Parenteral Nutrition; Rats; Rats, Inbred Strains; Zinc

1988
Whole body de novo amino acid synthesis in type I (insulin-dependent) diabetes studied with stable isotope-labeled leucine, alanine, and glycine.
    Diabetes, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Alanine; Amino Acids; Diabetes Mellitus, Type 1; Glucose; Glycine; Humans; Hyperglycemia; Insulin; Kinetics; Leucine; Male

1985
Studies on the mechanism of L-leucine-and alpha-ketoisocaproic acid-induced insulin release from perifused isolated pancreatic islets.
    Diabetologia, 1974, Volume: 10, Issue:2

    Topics: Animals; Caproates; Chemical Phenomena; Chemistry; Female; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; NADP; Obesity; Spectrometry, Fluorescence; Structure-Activity Relationship; Valerates

1974
Further studies on the amelioration of the characteristics of New Zealand Obese (NZO) mice following implantation of islets of Langerhans.
    Diabetologia, 1974, Volume: 10, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Cytological Techniques; Diffusion; Hyperglycemia; Hyperinsulinism; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Leucine; Male; Mice; Mice, Inbred Strains; Micropore Filters; Obesity; Peritoneal Cavity; Proinsulin; Streptozocin; Time Factors; Transplantation, Homologous; Tritium

1974
[Insuloma; on endocrine function].
    Naika. Internal medicine, 1965, Volume: 16, Issue:6

    Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; In Vitro Techniques; Insulin; Leucine; Tolbutamide

1965
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Tolbutamide; Trichlormethiazide

1968
[Apropos of 2 cases of insulinoma. Note on the effect of hypoglycemic effect of leucine].
    Acta clinica Belgica, 1969, Volume: 24, Issue:2

    Topics: Adenoma, Islet Cell; Aortography; Female; Humans; Hyperglycemia; Hypoglycemia; Leucine; Middle Aged; Pancreas; Pancreatic Neoplasms

1969
Transport of -aminoisobutyric acid in mammalian pancretic -cells.
    Diabetologia, 1971, Volume: 7, Issue:4

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Butyrates; Cyclic AMP; Diazoxide; Galactose; Glucose; Hyperglycemia; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Methionine; Mice; Monosaccharides; Obesity; Sodium

1971
Effects of glucose and other modifiers of insulin release on the oxidative metabolism of amino acids in micro-dissected pancreatic islets.
    The Biochemical journal, 1971, Volume: 123, Issue:4

    Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Citrates; Cyclic AMP; Depression, Chemical; Diazoxide; Epinephrine; Glucose; Glyburide; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Iodoacetates; Islets of Langerhans; Leucine; Male; Mice; Monosaccharides; Obesity; Oxidation-Reduction; Pyruvates; Stimulation, Chemical; Succinates

1971
Specificity of leucine stimulation of insulin release.
    Hormones, 1972, Volume: 3, Issue:1

    Topics: Amino Acids; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Isotopes; Islets of Langerhans; Isoleucine; Leucine; Mice; Obesity; Radioimmunoassay; Receptors, Cell Surface

1972
Microdetermination of free amino acids in pancreatic islets isolated from obese-hyperglycemic mice.
    Acta physiologica Scandinavica, 1972, Volume: 84, Issue:2

    Topics: Amino Acids; Animals; Binding Sites; Carbon Isotopes; Chromatography, Thin Layer; Dansyl Compounds; Fatty Acids, Nonesterified; Hyperglycemia; Islets of Langerhans; Leucine; Mice; Obesity; Taurine; Valine

1972
Transport of L-leucine and D-leucine into pancreatic -cells with reference to the mechanisms of amino acid-induced insulin release.
    Biochimica et biophysica acta, 1972, May-09, Volume: 266, Issue:2

    Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cells; Extracellular Space; Glyburide; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Mice; Mice, Inbred Strains; Obesity; Protein Biosynthesis; Receptors, Drug; Stereoisomerism; Sucrose; Tritium

1972
Uptake and oxidation of glutamic acid in mammalian pancreatic islets.
    Hormones, 1972, Volume: 3, Issue:3

    Topics: Alanine; Animals; Arginine; Carbon Isotopes; Female; Galactose; Glucose; Glutamates; Glyburide; Hyperglycemia; Insulin; Iodine Isotopes; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Sucrose; Time Factors; Tritium

1972
[Hypoglycemia].
    Actualites de physiologie pathologique, 1973, Volume: 4

    Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Leucine; Liver Glycogen; Pancreatic Neoplasms; Thyroid Hormones; Tolbutamide

1973
Mannoheptulose and insulin inhibition.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Blood Glucose; Child, Preschool; Female; Heptoses; Humans; Hyperglycemia; Insulin Antagonists; Islets of Langerhans; Leucine

1968
Leucyl-beta-naphthylamide-splitting enzymes in the mammalian endocrine pancreas.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Aminopeptidases; Animals; Electrophoresis, Disc; Female; Hydrogen-Ion Concentration; Hyperglycemia; Insulin; Islets of Langerhans; Kinetics; Leucine; Liver; Male; Mice; Naphthalenes; Obesity; Pancreas; Spectrophotometry; Starvation

1968
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Oxygen Consumption; Pancreas; Stimulation, Chemical; Tolbutamide; Urea; Valine

1969
Uptake of alanine, arginine and leucine by mammalian pancreatic beta-cells.
    Endocrinology, 1971, Volume: 89, Issue:6

    Topics: Alanine; Animals; Arginine; Carbon Isotopes; Diazoxide; Fructose; Glucose; Glyburide; Hyperglycemia; Islets of Langerhans; Leucine; Mice; Obesity; Pancreas; Pyruvates; Sodium; Stereoisomerism; Succinates; Time Factors

1971
[Early diagnosis of congenital metabolic diseases].
    Minerva medica, 1971, Nov-03, Volume: 62, Issue:83

    Topics: Diet Therapy; Galactosemias; Histidine; Homocystinuria; Humans; Hyperglycemia; Infant, Newborn; Leucine; Lipoproteins; Lysine; Metabolism, Inborn Errors; Phenylketonurias; Time Factors; Valine

1971
The clinical use of diazoxide in leucine-sensitive hypoglycemia.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diazoxide; Female; Humans; Hyperglycemia; Hypertrichosis; Hypoglycemia; Infant; Infant, Newborn; Insulin; Insulin Secretion; Leucine; Male

1968
Some evidence for pancreatic-adrenal interaction following lethal doses of 1-aminocyclopentanecarboxylic acid.
    Experientia, 1966, Feb-15, Volume: 22, Issue:2

    Topics: Adrenalectomy; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Blood Glucose; Cycloparaffins; Hyperglycemia; Islets of Langerhans; Leucine; Liver Glycogen; Rats; Valine

1966
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1969, Volume: 1, Issue:2

    Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Glucagon; Glycosuria; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Mice; Mice, Inbred Strains; Obesity; Pancreas; Tolbutamide

1969
[Quality of lipids and quantity of proteins synthesized in vivo by the normal mouse and the obese-hyperglycemic mouse from Bar Harbor].
    Bulletin de la Societe de chimie biologique, 1970, Apr-17, Volume: 52, Issue:3

    Topics: Acetates; Adipose Tissue; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Fatty Acids; Fatty Acids, Nonesterified; Female; Glycerides; Hyperglycemia; Leucine; Lipids; Liver; Mice; Muscles; Obesity; Phospholipids; Protein Biosynthesis; Rodent Diseases; Triglycerides

1970
Leucine-induced hyperglycemia in the goat.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:5

    Topics: Animals; Goats; Hyperglycemia; Infusions, Parenteral; Insulin; Leucine

1967
The mode of action of glymidine (Gondafon) with some speculations about the molecular and intracellular action of insulinotrophic drugs.
    Guy's Hospital reports, 1968, Volume: 117, Issue:4

    Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Leucine; Pancreas; Stimulation, Chemical; Sulfonamides

1968