peoniflorin has been researched along with Hyperglycemia* in 1 studies
1 other study(ies) available for peoniflorin and Hyperglycemia
| Article | Year |
|---|---|
A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKC
Hyperglycemia fluctuation is associated with diabetes mellitus (DM) complications when compared to persistent hyperglycemia. Previous studies have shown that paeoniflorin (PF), through its antiapoptosis, anti-inflammation, and antithrombotic properties, effectively protects against cardiovascular and cerebrovascular disease. However, the mechanism underlying the protection from PF against vascular injuries induced by hyperglycemia fluctuations remains poorly understood. Herein, we investigated the potential protective role of PF on human umbilical vein endothelial cells (HUVECs) subjected to intermittent glucose levels Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Inflammation; Male; Monoterpenes; Oxidative Stress; Protective Agents; Protein Kinase C beta; Rats, Sprague-Dawley; Vascular System Injuries | 2019 |