glycerol has been researched along with Hyperglycemia in 72 studies
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperglycemia in LKO mice led to increased liver weight and accumulation of triglycerides, glycogen and cholesterol together with elevated levels of Gro3P, dihydroxyacetone phosphate, acetyl-CoA and some Krebs cycle intermediates in liver." | 8.12 | Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia. ( Ahmad, R; Al-Mass, A; Al-Mulla, F; Chenier, I; Ghosh, A; Leung, YH; Lussier, R; Mugabo, Y; Murthy Madiraju, SR; Oppong, A; Peyot, ML; Possik, E; Poursharifi, P; Prentki, M; Sladek, R, 2022) |
| "We investigated the association of fasting serum glycerol and fatty acids (FAs) as predictors for worsening of hyperglycemia and incident type 2 diabetes." | 7.79 | Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. ( Ala-Korpela, M; Cederberg, H; Kangas, AJ; Kuusisto, J; Laakso, M; Mahendran, Y; Soininen, P; Uusitupa, M; Vangipurapu, J, 2013) |
| "To evaluate the in vivo effect of hyperglycemia per se on plasma free fatty acid (FFA) and glycerol concentrations, euglycemic and hyperglycemic clamp studies were performed in six overnight fasted dogs in the state of insulin deficiency produced by somatostatin (SRIF) infusion." | 7.68 | Hyperglycemia per se can reduce plasma free fatty acid and glycerol levels in the acutely insulin-deficient dog. ( Koh, CS; Lee, HK; Lee, KU; Min, HK; Park, KS; Rhee, BD, 1990) |
| " Hyperglycemia resulted in a significant decrease in the arterial blood glycerol (35%) and plasma free fatty acid concentrations (46%)." | 7.66 | Effect of hyperglycemia independent of changes in insulin or glucagon on lipolysis in the conscious dog. ( Cherrington, AD; Keller, U; Lacy, WW; Liljenquist, JE; Shulman, GI; Williams, PE, 1980) |
| "To evaluate the role of glucagon in the pathogenesis of diabetic ketoacidosis in man, we studied the effect of suppression of glucagon secretion by somatostatin on changes in plasma beta-hydroxybutyrate and glucose concentrations (as well as changes in their precursors) after acute withdrawal of insulin from seven patients with juvenile-type diabetes." | 7.65 | Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. ( Bier, DM; Forsham, PH; Gerich, JE; Karam, JH; Lorenzi, M; Schneider, V; Tsalikian, E, 1975) |
| "Insulin resistance was studied in seven non-obese male subjects with impaired glucose tolerance and four healthy, age and body-weight matched male control subjects by means of a continuous intravenous infusion of somatostatin, glucose and insulin over 150 min." | 5.26 | Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance. ( Besch, W; Ratzmann, KP; Schulz, B; Witt, S, 1981) |
| " Hyperglycemia in LKO mice led to increased liver weight and accumulation of triglycerides, glycogen and cholesterol together with elevated levels of Gro3P, dihydroxyacetone phosphate, acetyl-CoA and some Krebs cycle intermediates in liver." | 4.12 | Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia. ( Ahmad, R; Al-Mass, A; Al-Mulla, F; Chenier, I; Ghosh, A; Leung, YH; Lussier, R; Mugabo, Y; Murthy Madiraju, SR; Oppong, A; Peyot, ML; Possik, E; Poursharifi, P; Prentki, M; Sladek, R, 2022) |
| "Leptin can reverse hyperglycemia in rodent models of type 1 diabetes." | 3.83 | Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy. ( Covey, SD; Denroche, HC; Kieffer, TJ; Mojibian, M; Neumann, UH, 2016) |
| " Characterization of overt hyperglycemia in insulin receptor mutant (Insr(P1195L/+)) mice exposed to HFD (Insr(P1195L/+)/HFD mice) revealed increased glucose-6-phosphatase (G6pc) expression in liver and increased gluconeogenesis from glycerol." | 3.81 | Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet. ( Jiang, M; Lee, EY; Miki, T; Minokoshi, Y; Sakurai, K; Shirasawa, T; Tachibana, K; Tanaka, T; Toda, C; Vidal-Puig, A; Yokote, K; Zhang, X, 2015) |
| "We investigated the association of fasting serum glycerol and fatty acids (FAs) as predictors for worsening of hyperglycemia and incident type 2 diabetes." | 3.79 | Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. ( Ala-Korpela, M; Cederberg, H; Kangas, AJ; Kuusisto, J; Laakso, M; Mahendran, Y; Soininen, P; Uusitupa, M; Vangipurapu, J, 2013) |
| " Microdialysis measurements of interstitial glycerol and determination of fractional glycerol release were carried out during standardized combinations of relative hypoinsulinemia/moderate hyperglycemia (11 mmol/liter), hyperinsulinemia/ normoglycemia (5 mmol/liter), and hyperinsulinemia/moderate hyperglycemia, respectively." | 3.72 | Combined hyperinsulinemia and hyperglycemia, but not hyperinsulinemia alone, suppress human skeletal muscle lipolytic activity in vivo. ( Bolinder, J; Enoksson, S; Hagström-Toft, E; Qvisth, V; Sherwin, RS; Sjöberg, S, 2004) |
| " Each study consisted of an equilibration (-140 to -40 min), a control (-40 to 0 min), and a test period (0 to 180 min), during which BAY R3401 (10 mg/kg), a glycogen phosphorylase inhibitor, was administered orally, either alone to create mild hypoglycemia or with peripheral glucose infusion to maintain euglycemia or create mild hyperglycemia." | 3.71 | Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog. ( Cherrington, AD; Emshwiller, MG; Flattem, N; Igawa, K; Neal, DW; Shiota, M, 2001) |
| "To evaluate the in vivo effect of hyperglycemia per se on plasma free fatty acid (FFA) and glycerol concentrations, euglycemic and hyperglycemic clamp studies were performed in six overnight fasted dogs in the state of insulin deficiency produced by somatostatin (SRIF) infusion." | 3.68 | Hyperglycemia per se can reduce plasma free fatty acid and glycerol levels in the acutely insulin-deficient dog. ( Koh, CS; Lee, HK; Lee, KU; Min, HK; Park, KS; Rhee, BD, 1990) |
| " Hyperglycemia resulted in a significant decrease in the arterial blood glycerol (35%) and plasma free fatty acid concentrations (46%)." | 3.66 | Effect of hyperglycemia independent of changes in insulin or glucagon on lipolysis in the conscious dog. ( Cherrington, AD; Keller, U; Lacy, WW; Liljenquist, JE; Shulman, GI; Williams, PE, 1980) |
| "To evaluate the role of glucagon in the pathogenesis of diabetic ketoacidosis in man, we studied the effect of suppression of glucagon secretion by somatostatin on changes in plasma beta-hydroxybutyrate and glucose concentrations (as well as changes in their precursors) after acute withdrawal of insulin from seven patients with juvenile-type diabetes." | 3.65 | Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. ( Bier, DM; Forsham, PH; Gerich, JE; Karam, JH; Lorenzi, M; Schneider, V; Tsalikian, E, 1975) |
| " GSK256073 was dosed 5 mg every 12 h before breakfast and supper (BID), 10 mg every 24 h before breakfast (QD), 25 mg BID and 50 mg QD." | 2.78 | GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus. ( Byerly, RL; Dobbins, RL; Gao, FF; Le Monnier de Gouville, AC; Mahar, KM; Nachbaur, GJ; Napolitano, A; Shearn, SP, 2013) |
| "Glycerol concentration was 267 +/- 41 micromol/L and 133 +/- 40 micromol/L in PF and venous blood, respectively (P = 0." | 2.73 | Microdialysis technique as a monitoring system for acute complications of diabetes. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2008) |
| "We propose that hyperglycemia is the driving force that aggravates overproduction of VLDL1 in DM2." | 2.71 | Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia. ( Adiels, M; Borén, J; Caslake, MJ; Olofsson, SO; Packard, C; Soro, A; Stewart, P; Taskinen, MR; Wennberg, B; Westerbacka, J, 2005) |
| "Seven obese nondiabetic women with postprandial hyperglycemia and nine lean healthy women were recruited." | 1.37 | Impaired delivery of insulin to adipose tissue and skeletal muscle in obese women with postprandial hyperglycemia. ( Jansson, PA; Lönnroth, P; Sandqvist, M; Schmelz, M; Strindberg, L, 2011) |
| "In conclusion, GIP in combination with hyperinsulinemia and slight hyperglycemia increased adipose tissue blood flow, glucose uptake, and FFA re-esterification, thus resulting in increased TAG deposition in abdominal subcutaneous adipose tissue." | 1.36 | Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans. ( Asmar, M; Bülow, J; Holst, JJ; Madsbad, S; Simonsen, L; Stallknecht, B, 2010) |
| "Thus in type 2 diabetes, postprandial hyperglycemia is primarily due to increased glucose release; hyperglycemia overcomes the effects of impaired insulin secretion and sensitivity on glucose transport, but intracellular defects persist so that pathways of glucose metabolism are abnormal and glucose is shunted away from normal sites of storage (e." | 1.33 | Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes. ( Dostou, JM; Gerich, JE; Gosmanov, NR; Meyer, C; Szoke, E; Welle, SL; Wittlin, SD; Woerle, HJ, 2006) |
| "Glucose effectiveness is impaired in type 2 diabetes." | 1.31 | Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects. ( Gabriely, I; Hawkins, M; Reddy, K; Rossetti, L; Shamoon, H; Wozniak, R, 2002) |
| " Linear dose-response relationships (p less than 0." | 1.28 | Impaired glucose tolerance is characterized by multiple abnormalities in the regulation of intermediary metabolism. ( Krentz, AJ; Nattrass, M; Singh, BM, 1991) |
| "The significance of ketosis in this syndrome has been evaluated from several viewpoints." | 1.27 | Can marked hyperglycemia occur without ketosis? ( Halperin, ML; Marsden, PA; Singer, GG; West, ML, 1985) |
| "Insulin resistance was studied in seven non-obese male subjects with impaired glucose tolerance and four healthy, age and body-weight matched male control subjects by means of a continuous intravenous infusion of somatostatin, glucose and insulin over 150 min." | 1.26 | Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance. ( Besch, W; Ratzmann, KP; Schulz, B; Witt, S, 1981) |
| "Hyperglycemia was seen in 13 of stressed and in only one of control premature infants." | 1.26 | Hyperglycemia in stressed small premature neonates. ( Baccaro, MM; Lilien, LD; Pildes, RS; Rosenfield, RL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (43.06) | 18.7374 |
| 1990's | 8 (11.11) | 18.2507 |
| 2000's | 18 (25.00) | 29.6817 |
| 2010's | 13 (18.06) | 24.3611 |
| 2020's | 2 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, P | 1 |
| Hansen, JS | 1 |
| Saba, KH | 1 |
| Bergman, A | 1 |
| Negoita, F | 1 |
| Gourdon, P | 1 |
| Hagström-Andersson, A | 1 |
| Lindkvist-Petersson, K | 1 |
| Al-Mass, A | 1 |
| Poursharifi, P | 1 |
| Peyot, ML | 1 |
| Lussier, R | 1 |
| Chenier, I | 1 |
| Leung, YH | 1 |
| Ghosh, A | 1 |
| Oppong, A | 1 |
| Possik, E | 1 |
| Mugabo, Y | 1 |
| Ahmad, R | 1 |
| Sladek, R | 1 |
| Murthy Madiraju, SR | 1 |
| Al-Mulla, F | 1 |
| Prentki, M | 1 |
| Nikolaou, KC | 1 |
| Vatandaslar, H | 1 |
| Meyer, C | 2 |
| Schmid, MW | 1 |
| Tuschl, T | 1 |
| Stoffel, M | 1 |
| Dobbins, RL | 1 |
| Shearn, SP | 1 |
| Byerly, RL | 1 |
| Gao, FF | 1 |
| Mahar, KM | 1 |
| Napolitano, A | 1 |
| Nachbaur, GJ | 1 |
| Le Monnier de Gouville, AC | 1 |
| Rajpal, A | 1 |
| Dube, S | 1 |
| Carvalho, F | 1 |
| Simoes, AR | 1 |
| Figueiredo, A | 1 |
| Basu, A | 2 |
| Jones, J | 1 |
| Basu, R | 2 |
| Mahendran, Y | 1 |
| Cederberg, H | 1 |
| Vangipurapu, J | 1 |
| Kangas, AJ | 1 |
| Soininen, P | 1 |
| Kuusisto, J | 1 |
| Uusitupa, M | 1 |
| Ala-Korpela, M | 1 |
| Laakso, M | 1 |
| Haglind, CB | 1 |
| Nordenström, A | 1 |
| Ask, S | 1 |
| von Döbeln, U | 1 |
| Gustafsson, J | 1 |
| Stenlid, MH | 1 |
| Karstoft, K | 1 |
| Mortensen, SP | 1 |
| Knudsen, SH | 1 |
| Solomon, TP | 1 |
| Herring, RA | 1 |
| Shojaee-Moradie, F | 1 |
| Umpleby, AM | 1 |
| Jones, R | 1 |
| Jackson, N | 1 |
| Russell-Jones, DL | 1 |
| Lee, JT | 1 |
| Huang, Z | 1 |
| Pan, K | 1 |
| Zhang, HJ | 1 |
| Woo, CW | 1 |
| Xu, A | 1 |
| Wong, CM | 1 |
| Lee, EY | 1 |
| Sakurai, K | 1 |
| Zhang, X | 1 |
| Toda, C | 1 |
| Tanaka, T | 1 |
| Jiang, M | 1 |
| Shirasawa, T | 1 |
| Tachibana, K | 1 |
| Yokote, K | 1 |
| Vidal-Puig, A | 1 |
| Minokoshi, Y | 1 |
| Miki, T | 1 |
| Neumann, UH | 1 |
| Denroche, HC | 1 |
| Mojibian, M | 1 |
| Covey, SD | 1 |
| Kieffer, TJ | 1 |
| Perry, RJ | 1 |
| Peng, L | 1 |
| Cline, GW | 1 |
| Petersen, KF | 1 |
| Shulman, GI | 3 |
| Asmar, M | 1 |
| Simonsen, L | 1 |
| Madsbad, S | 1 |
| Stallknecht, B | 1 |
| Holst, JJ | 1 |
| Bülow, J | 1 |
| Sandqvist, M | 1 |
| Strindberg, L | 1 |
| Schmelz, M | 1 |
| Lönnroth, P | 1 |
| Jansson, PA | 2 |
| Lourido, J | 1 |
| Ederoth, P | 1 |
| Sundvall, N | 1 |
| Ungerstedt, U | 3 |
| Nordström, CH | 2 |
| Shah, P | 1 |
| Vella, A | 1 |
| Adkins, A | 1 |
| Schwenk, WF | 1 |
| Johnson, CM | 1 |
| Nair, KS | 1 |
| Jensen, MD | 1 |
| Rizza, RA | 1 |
| Bélanger, P | 1 |
| Fillion, Y | 1 |
| Couturier, K | 1 |
| Gauthier, MS | 1 |
| Lavoie, JM | 1 |
| Diaz-Parejo, P | 1 |
| Ståhl, N | 1 |
| Xu, W | 1 |
| Reinstrup, P | 1 |
| TREBLE, DH | 1 |
| MAYER, J | 1 |
| JAVID, M | 1 |
| GILBOE, D | 1 |
| CESARIO, T | 1 |
| Qvisth, V | 1 |
| Hagström-Toft, E | 1 |
| Enoksson, S | 1 |
| Sherwin, RS | 1 |
| Sjöberg, S | 1 |
| Bolinder, J | 1 |
| Adiels, M | 1 |
| Borén, J | 1 |
| Caslake, MJ | 1 |
| Stewart, P | 1 |
| Soro, A | 1 |
| Westerbacka, J | 1 |
| Wennberg, B | 1 |
| Olofsson, SO | 1 |
| Packard, C | 1 |
| Taskinen, MR | 1 |
| Rajamand, N | 1 |
| Brismar, K | 1 |
| Woerle, HJ | 1 |
| Szoke, E | 1 |
| Dostou, JM | 1 |
| Wittlin, SD | 1 |
| Gosmanov, NR | 1 |
| Welle, SL | 1 |
| Gerich, JE | 2 |
| Dicostanzo, CA | 2 |
| Dardevet, DP | 1 |
| Neal, DW | 4 |
| Lautz, M | 1 |
| Allen, E | 1 |
| Snead, W | 1 |
| Cherrington, AD | 6 |
| Everett-Grueter, C | 1 |
| Edgerton, DS | 1 |
| Donahue, EP | 1 |
| Vaughan, S | 1 |
| Chu, CA | 1 |
| Sindelar, DK | 1 |
| Kishore, P | 1 |
| Tonelli, J | 1 |
| Koppaka, S | 1 |
| Fratila, C | 1 |
| Bose, A | 1 |
| Lee, DE | 1 |
| Reddy, K | 2 |
| Hawkins, M | 2 |
| Ciechanowska, A | 1 |
| Ladyzynski, P | 1 |
| Wojcicki, JM | 1 |
| Sabalinska, S | 1 |
| Krzymien, J | 1 |
| Pulawska, E | 1 |
| Karnafel, W | 1 |
| Foltynski, P | 1 |
| Kawiak, J | 1 |
| Moore, MC | 2 |
| Smith, MS | 1 |
| Farmer, B | 1 |
| Rodewald, TD | 1 |
| Williams, PE | 2 |
| Liljenquist, JE | 1 |
| Lacy, WW | 1 |
| Keller, U | 1 |
| Ratzmann, KP | 1 |
| Besch, W | 1 |
| Witt, S | 1 |
| Schulz, B | 1 |
| Nosadini, R | 1 |
| Noy, GA | 1 |
| Alberti, KG | 1 |
| Hodson, A | 1 |
| Orskoy, H | 1 |
| van der Merwe, TM | 1 |
| Eklund, L | 1 |
| Lönnroth, PN | 1 |
| Giacca, A | 1 |
| Fisher, SJ | 1 |
| Shi, ZQ | 1 |
| Gupta, R | 1 |
| Lickley, HL | 1 |
| Skottner, A | 1 |
| Anderson, GH | 1 |
| Efendic, S | 1 |
| Vranic, M | 1 |
| Magnan, C | 1 |
| Laury, MC | 1 |
| Adnot, P | 1 |
| Doaré, L | 1 |
| Boucontet, L | 1 |
| Kergoat, M | 1 |
| Pénicaud, L | 1 |
| Ktorza, A | 1 |
| Gilbert, M | 1 |
| MacLaren, DP | 1 |
| Reilly, T | 1 |
| Campbell, IT | 1 |
| Hopkin, C | 1 |
| Landreaud, M | 1 |
| Nougué, J | 1 |
| Flattem, N | 1 |
| Igawa, K | 1 |
| Shiota, M | 2 |
| Emshwiller, MG | 1 |
| Lattermann, R | 1 |
| Schricker, T | 1 |
| Wachter, U | 1 |
| Georgieff, M | 1 |
| Goertz, A | 1 |
| Galassetti, P | 1 |
| Monohan, M | 1 |
| Gabriely, I | 1 |
| Wozniak, R | 1 |
| Rossetti, L | 1 |
| Shamoon, H | 1 |
| Hurwitz, BJ | 1 |
| Rottenberg, DA | 1 |
| Lilien, LD | 1 |
| Rosenfield, RL | 1 |
| Baccaro, MM | 1 |
| Pildes, RS | 1 |
| Schwartz, MZ | 1 |
| Levey, RH | 1 |
| Lorenzi, M | 1 |
| Bier, DM | 1 |
| Schneider, V | 1 |
| Tsalikian, E | 1 |
| Karam, JH | 1 |
| Forsham, PH | 1 |
| Kreutner, W | 1 |
| Springer, SC | 1 |
| Sherwood, JE | 1 |
| Sears, ES | 1 |
| Tanabe, S | 1 |
| Kameoka, K | 1 |
| Wahren, J | 1 |
| Felig, P | 1 |
| Krentz, AJ | 1 |
| Singh, BM | 1 |
| Nattrass, M | 1 |
| Park, KS | 1 |
| Rhee, BD | 1 |
| Lee, KU | 1 |
| Lee, HK | 1 |
| Koh, CS | 1 |
| Min, HK | 1 |
| Paolisso, G | 1 |
| Buonocore, S | 1 |
| Gentile, S | 1 |
| Sgambato, S | 1 |
| Varricchio, M | 1 |
| Scheen, A | 1 |
| D'Onofrio, F | 1 |
| Lefèbvre, PJ | 1 |
| Stevenson, RW | 1 |
| Hutson, NJ | 1 |
| Krupp, MN | 1 |
| Volkmann, RA | 1 |
| Holland, GF | 1 |
| Eggler, JF | 1 |
| Clark, DA | 1 |
| McPherson, RK | 1 |
| Hall, KL | 1 |
| Danbury, BH | 1 |
| Belfiore, F | 1 |
| Iannello, S | 1 |
| Rabuazzo, AM | 1 |
| Campione, R | 1 |
| Beylot, M | 1 |
| Sautot, G | 1 |
| Dechaud, H | 1 |
| Cohen, R | 1 |
| Riou, JP | 1 |
| Serusclat, P | 1 |
| Mornex, R | 1 |
| Mikines, KJ | 1 |
| Farrell, PA | 1 |
| Sonne, B | 1 |
| Tronier, B | 1 |
| Galbo, H | 1 |
| Halperin, ML | 1 |
| Marsden, PA | 1 |
| Singer, GG | 1 |
| West, ML | 1 |
| Salmon, MA | 1 |
| Esiri, MM | 1 |
| Ruderman, NB | 1 |
| Koschinsky, T | 2 |
| Gries, FA | 3 |
| Herberg, L | 3 |
| Neuvonen, PJ | 2 |
| Westermann, E | 3 |
| Beyer, J | 1 |
| Cordes, U | 1 |
| Sell, G | 1 |
| Schöffling, K | 1 |
| Vapaatalo, H | 1 |
| Bieck, P | 1 |
| Stock, K | 1 |
| Hesse-Wortmann, C | 1 |
| Hammerl, H | 1 |
| Kränzl, C | 1 |
| Nebosis, G | 1 |
| Pichler, O | 1 |
| Studlar, M | 1 |
| Welton, RF | 1 |
| Martin, RJ | 1 |
| Baumgardt, BR | 1 |
| Kaplan, ML | 1 |
| Fried, GH | 1 |
| Lockey, SD | 1 |
| Glennon, JA | 1 |
| Reed, CE | 1 |
| Mitzkat, HJ | 1 |
| Meyer, U | 1 |
| McCraw, EF | 1 |
| Wagle, SR | 1 |
| Patterson, C | 1 |
| Ashmore, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Single Blind, Placebo-controlled, Three Period Crossover, Dose Selection Study to Evaluate the Effect of GSK256073, an HM74A Receptor Agonist, on Glucose and NEFA 24 Hour Profile in Type 2 Diabetic Patients.[NCT01147861] | Phase 1 | 39 participants (Actual) | Interventional | 2010-07-01 | Completed | ||
| A Dietary Intervention With Functional Foods Reduce Metabolic Endotoxemia and Attenuates Biochemical Abnormalities in Subjects With Type 2 Diabetes by Modifying the Gut Microbiota.[NCT03421301] | 81 participants (Actual) | Interventional | 2014-08-07 | Completed | |||
| An Acute Randomized Dose-finding Equivalence Trial of Small, Catalytic Doses of Fructose and Allulose on Postprandial Carbohydrate Metabolism: The Fructose and Allulose Catalytic Effects (FACE) Study[NCT02459834] | 50 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for glycerol and Hyperglycemia
| Article | Year |
|---|---|
GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus.
Topics: C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Adm | 2013 |
Direct effect of incretin hormones on glucose and glycerol metabolism and hemodynamics.
Topics: Adolescent; Adult; Blood Glucose; Blood Pressure; Carotid Artery, Common; Glucose; Glucose Clamp Tec | 2015 |
Effect of subcutaneous insulin detemir on glucose flux and lipolysis during hyperglycaemia in people with type 1 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Glycated Hemoglobin; Glycerol; Hum | 2015 |
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia.
Topics: Adult; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, VLDL; Deuterium; Diabetes Me | 2005 |
Time-dependent effects of free fatty acids on glucose effectiveness in type 2 diabetes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Gluco | 2006 |
Microdialysis technique as a monitoring system for acute complications of diabetes.
Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 2008 |
Effects of hyperglycemia on in vivo adipose tissue metabolism studied with microdialysis in IDDM subjects.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Gl | 1994 |
Understanding the mechanisms by which isoflurane modifies the hyperglycemic response to surgery.
Topics: Aged; Analgesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Catecholamines; Double-B | 2001 |
64 other studies available for glycerol and Hyperglycemia
| Article | Year |
|---|---|
Aquaglyceroporins and orthodox aquaporins in human adipocytes.
Topics: Adipocytes; Aquaglyceroporins; Aquaporin 1; Aquaporin 3; Aquaporins; Gene Expression Regulation; Gly | 2022 |
Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia.
Topics: Animals; Glucose; Glycerol; Glycogen; Hyperglycemia; Liver; Male; Mice; Phosphoric Monoester Hydrola | 2022 |
The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing.
Topics: 3' Untranslated Regions; Alternative Splicing; Animals; Base Sequence; Cell Line, Tumor; Fatty Liver | 2019 |
Effects of transaldolase exchange on estimates of gluconeogenesis in type 2 diabetes.
Topics: Acetic Acid; Aged; Carbon Radioisotopes; Deuterium Oxide; Diabetes Mellitus, Type 2; Fasting; Female | 2013 |
Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men.
Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Monounsaturated; | 2013 |
Increased and early lipolysis in children with long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency during fast.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Age Factors; Biomarkers; Blood Glucose; Calorimetry, Indirect; Car | 2015 |
Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.
Topics: Adipocytes; Adipose Tissue, White; Animals; Gluconeogenesis; Glycerol; Hyperglycemia; Lipocalins; Li | 2016 |
Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Bile Acids and Salts; Blood Gluco | 2015 |
Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus, Exper | 2016 |
A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo.
Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Animals; Blood Glucose; Fasting; Feeding Behavior; Glucose | 2017 |
Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids; Gastric Inhibitory Polypeptide; Glucose Clamp Techniqu | 2010 |
Impaired delivery of insulin to adipose tissue and skeletal muscle in obese women with postprandial hyperglycemia.
Topics: Adipose Tissue; Biopsy; Body Weight; Cell Size; Female; Glucose; Glycerol; Humans; Hyperglycemia; In | 2011 |
Correlation between blood glucose concentration and glucose concentration in subcutaneous adipose tissue evaluated with microdialysis during intensive care.
Topics: Adipose Tissue; Blood Glucose; Brain Injuries; Critical Care; Energy Metabolism; Glycerol; Humans; H | 2002 |
Elevated free fatty acids impair glucose metabolism in women: decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia.
Topics: Adult; C-Peptide; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Human Growth Hormone; Human | 2003 |
Effects of inducing physiological hyperglucagonemia on metabolic responses to exercise.
Topics: 3-Hydroxybutyric Acid; Animals; Ankle; Blood Glucose; C-Peptide; Dose-Response Relationship, Drug; E | 2003 |
Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma.
Topics: Blood Glucose; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Female; Glutamic Acid | 2003 |
GLYCEROLKINASE ACTIVITY IN WHITE ADIPOSE TISSUE OF OBESE-HYPERGLYCAEMIC MICE.
Topics: Adenosine Triphosphate; Adipose Tissue; Adipose Tissue, White; Animals; Carbohydrate Metabolism; Car | 1963 |
THE REBOUND PHENOMENON AND HYPERTONIC SOLUTIONS.
Topics: Animals; Cerebrospinal Fluid; Dogs; Glycerol; Glycine; Hyperglycemia; Hypertonic Solutions; Intracra | 1964 |
Combined hyperinsulinemia and hyperglycemia, but not hyperinsulinemia alone, suppress human skeletal muscle lipolytic activity in vivo.
Topics: Adipose Tissue; Adult; Glycerol; Humans; Hyperglycemia; Hyperinsulinism; Lipolysis; Lipoprotein Lipa | 2004 |
Subcutaneous microdialysis before and after an oral glucose tolerance test: a method to determine insulin resistance in the subcutaneous adipose tissue in diabetes mellitus.
Topics: Adult; Anthropometry; Blood Glucose; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 1; | 2005 |
Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes.
Topics: Alanine; Blood Glucose; Carbon Dioxide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Femal | 2006 |
Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal.
Topics: Animals; Blood Glucose; Dogs; Glucagon; Glucose; Glycerol; Hyperglycemia; Infusions, Intravenous; In | 2006 |
The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Blood Glucose; Cyclic AMP; Dogs; Fat Emu | 2006 |
Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake.
Topics: Animals; Blood Glucose; Carbon; Catheterization; Dogs; Dose-Response Relationship, Drug; Enzyme Inhi | 2008 |
Effect of hyperglycemia independent of changes in insulin or glucagon on lipolysis in the conscious dog.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Hyper | 1980 |
Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Glyce | 1981 |
The metabolic response to hyperglycaemic clamping in insulin-dependent diabetes.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glycerol; Hu | 1981 |
Insulin-like growth factor-I and insulin have no differential effects on glucose production and utilization under conditions of hyperglycemia.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Glycerol | 1994 |
Hormonal counterregulation failure in rats is related to previous hyperglycaemia-hyperinsulinaemia.
Topics: Animals; Blood Glucose; Body Weight; Catecholamines; Eating; Female; Glucagon; Glycerol; Hyperglycem | 1998 |
Hormonal and metabolic responses to maintained hyperglycemia during prolonged exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Epinephrine; Exercise; Exercise Test; Fatty Acids, None | 1999 |
[Concerning hyperglycerolemias].
Topics: Bias; Diagnostic Errors; Glycerol; Humans; Hyperglycemia; Hypertriglyceridemia; Terminology as Topic | 2000 |
Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog.
Topics: Alanine; Animals; Arteries; Blood Glucose; Dogs; Female; Gluconeogenesis; Glucose; Glycerol; Glycoge | 2001 |
Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog.
Topics: Alanine; Animals; Blood Glucose; Dogs; Duodenum; Fructose; Glucagon; Gluconeogenesis; Glucose; Glyce | 2002 |
Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects.
Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucagon; Glu | 2002 |
Letter: Glycerol, cerebral oedema, and diabetes.
Topics: Brain Edema; Diabetes Complications; Glycerol; Humans; Hyperglycemia; Male; Middle Aged | 1975 |
Hyperglycemia in stressed small premature neonates.
Topics: Blood Glucose; Female; Glucose; Glycerol; Humans; Hyaline Membrane Disease; Hydrocortisone; Hypergly | 1979 |
Glycerin toxicity in an infant following enteric administration.
Topics: Glycerol; Hematoma, Subdural; Humans; Hyperglycemia; Infant, Newborn; Intestinal Mucosa; Male | 1978 |
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon.
Topics: Adult; Alanine; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Type 1; Diabetic Ketoacidosi | 1975 |
Resistance of gluconeogenic and glycogenic pathways in obese-hyperglycemic mice.
Topics: Alanine; Animals; Enzyme Activation; Female; Genotype; Gluconeogenesis; Glucose Tolerance Test; Glyc | 1975 |
Nonkitotoc hyperosmolar hyperglycemia during glycerol therapy for cerebral edema.
Topics: Aged; Blood Glucose; Brain Edema; Diabetes Complications; Diabetes Mellitus; Female; Glycerol; Human | 1976 |
Effect of feeding a carbohydrate-free diet on the growth and metabolism of preruminant kids.
Topics: Age Factors; Animals; Body Weight; Carbohydrates; Cattle; Cholesterol; Deficiency Diseases; Energy M | 1976 |
Renal substrate exchange in human diabetes mellitus.
Topics: Adult; Amino Acids; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Gluconeogenesis; G | 1975 |
Impaired glucose tolerance is characterized by multiple abnormalities in the regulation of intermediary metabolism.
Topics: Alanine; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose Tolerance Test; Glycerol; Hum | 1991 |
Hyperglycemia per se can reduce plasma free fatty acid and glycerol levels in the acutely insulin-deficient dog.
Topics: Acute Disease; Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; | 1990 |
Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age.
Topics: 3-Hydroxybutyric Acid; Adult; Age Factors; Aged; Aging; Blood Glucose; C-Peptide; Drug Administratio | 1990 |
Actions of novel antidiabetic agent englitazone in hyperglycemic hyperinsulinemic ob/ob mice.
Topics: 3-Hydroxybutyric Acid; Animals; Benzopyrans; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; | 1990 |
Metabolic effects of short-term fasting in obese hyperglycaemic humans and mice.
Topics: Adult; Animals; Fasting; Female; Fructose-Bisphosphatase; Glucokinase; Gluconeogenesis; Glucose Tole | 1987 |
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; | 1985 |
Postexercise dose-response relationship between plasma glucose and insulin secretion.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Blood Pressure; C-Peptide; Calorimetry; Epinep | 1988 |
Can marked hyperglycemia occur without ketosis?
Topics: Acetone; Acidosis; Brain; Diabetic Coma; Glucose; Glycerides; Glycerol; Glycogen; Humans; Hyperglyce | 1985 |
Myopathic disorder associated with mitochondrial abnormalities, hyperglycaemia, and hyperketonaemia.
Topics: Acetoacetates; Age Factors; Blood Glucose; Child, Preschool; Creatine Kinase; Cytoplasmic Granules; | 1971 |
Regulation of glycerol kinase by insulin in isolated fat cells and liver of Bar Harbor obese mice.
Topics: Adipose Tissue; Age Factors; Amino Sugars; Animals; Anti-Bacterial Agents; Dactinomycin; Enzyme Indu | 1971 |
Studies on some metabolic effects of dopa and dopamine in the rat.
Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Blood Glucose; Dihydroxyphenylalanine; Dopamin | 1974 |
[Extrapancreatic effects of sulfonylurea compounds. 3. Studies on the additional blood sugar decreasing and antilipolytic effect of tolbutamide, glibornuride, and glibenclamide on completely pancreatectomized dogs, chronically treated with insulin during
Topics: Animals; Blood Glucose; Camphanes; Dogs; Fatty Acids, Nonesterified; Glyburide; Glycerol; Hyperglyce | 1972 |
On the mechanism of some metabolic actions of dopamine.
Topics: Animals; Blood Glucose; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Drug Antagonism; Fatty | 1971 |
[Effect of cyclic adenosine-3',5'-monophosphate (3',5'-AMP) and its dibutyryl derivative (DBA) on lipolysis, glycogenolysis and corticosterone synthesis].
Topics: Adenine Nucleotides; Adipose Tissue; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticost | 1969 |
Effect of weight and cell size on hormone-induced lipolysis in New Zealand obese mice and American obese hyperglycemic mice.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Body Weight; Disease Models, Animal; Epididymi | 1970 |
[Metabolic studies and therapeutic experiences with the beta-receptor blockader 4-(2-hydroxy-3-isopropylamino-propoxy)-indol (LB 46)].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Carbohydrate Metabolism; Fatt | 1972 |
Effects of feeding and exercise regimens on adipose tissue glycerokinase activity and body composition of lean and obese mice.
Topics: Adipose Tissue; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; | 1973 |
Adaptive enzyme responses in adipose tissue of obese hyperglycemic mice.
Topics: Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Enzyme Induction; Epididymis; Fasting; Glu | 1973 |
Comparison of some metabolic responses in normal and asthmatic subjects to epinephrine and glucagon.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Gluc | 1967 |
Hepatic metabolite pattern of the energy-linked metabolism in 'instant diabetes' after mannohhetulose.
Topics: Acetoacetates; Animals; Fatty Acids, Nonesterified; Gluconeogenesis; Glycerol; Glycolysis; Hydroxybu | 1970 |
Glycerol kinase activity in isolated fat cells of BHob mice.
Topics: Adipose Tissue; Age Factors; Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; E | 1970 |
Cortisol induction of lipolysis in adrenalectomized diabetic rats.
Topics: Adipose Tissue; Adrenalectomy; Animals; Cycloheximide; Dactinomycin; Diabetes Mellitus, Experimental | 1969 |