propofol has been researched along with Hyperglycemia in 14 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rat heart-derived H9c2 cells were exposed to high glucose (HG) for 48 h (h), then subjected to hypoxia/reoxygenation (H/R, composed of 8 h of hypoxia followed by 12 h of reoxygenation) in the absence or presence of postconditioning with various concentrations of propofol (P-PostC) at the onset of reoxygenation." | 8.02 | Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia. ( Cai, Y; Chen, H; Han, H; Han, RH; Huang, HM; Liu, DY; Liu, X; Tang, J; Xia, ZY; Xie, X; Zeng, F; Zhang, LQ, 2021) |
| "Rat pial arteriole responses to ACh are maintained during conditions of acute hyperglycemia with propofol anesthesia but suppressed compared with normoglycemia with desflurane anesthesia." | 8.02 | Propofol But Not Desflurane Maintains Rat Cerebral Arteriolar Responses to Acetylcholine During Acute Hyperglycemia. ( Fukuoka, N; Iida, H; Kito, K; Nagase, K; Sakata, K; Tanabe, K, 2021) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 7.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "Propofol counteracts cardiomyocyte H/R injury by attenuating mitochondrial damage and improving mitochondrial biogenesis through upregulating Cav-3 during hyperglycemia." | 7.85 | Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia. ( Cai, S; Deng, F; Li, H; Liu, X; Miao, HL; Wang, S; Xia, Z; Xie, GL; Xie, X; Yang, C; Zhang, L, 2017) |
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 7.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| "Sixty rats were randomly assigned to four groups: normoglycemia-etomidate, normoglycemia-propofol, hyperglycemia-etomidate, and hyperglycemia-propofol." | 7.79 | Propofol attenuates renal ischemia-reperfusion injury aggravated by hyperglycemia. ( Jun, JH; Kwak, YL; Lim, BJ; Shim, JK; Yoo, KJ; Yoo, YC, 2013) |
| "To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 7.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
| "Rat heart-derived H9c2 cells were exposed to high glucose (HG) for 48 h (h), then subjected to hypoxia/reoxygenation (H/R, composed of 8 h of hypoxia followed by 12 h of reoxygenation) in the absence or presence of postconditioning with various concentrations of propofol (P-PostC) at the onset of reoxygenation." | 4.02 | Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia. ( Cai, Y; Chen, H; Han, H; Han, RH; Huang, HM; Liu, DY; Liu, X; Tang, J; Xia, ZY; Xie, X; Zeng, F; Zhang, LQ, 2021) |
| "Rat pial arteriole responses to ACh are maintained during conditions of acute hyperglycemia with propofol anesthesia but suppressed compared with normoglycemia with desflurane anesthesia." | 4.02 | Propofol But Not Desflurane Maintains Rat Cerebral Arteriolar Responses to Acetylcholine During Acute Hyperglycemia. ( Fukuoka, N; Iida, H; Kito, K; Nagase, K; Sakata, K; Tanabe, K, 2021) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 3.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "Propofol counteracts cardiomyocyte H/R injury by attenuating mitochondrial damage and improving mitochondrial biogenesis through upregulating Cav-3 during hyperglycemia." | 3.85 | Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia. ( Cai, S; Deng, F; Li, H; Liu, X; Miao, HL; Wang, S; Xia, Z; Xie, GL; Xie, X; Yang, C; Zhang, L, 2017) |
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 3.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| "Sixty rats were randomly assigned to four groups: normoglycemia-etomidate, normoglycemia-propofol, hyperglycemia-etomidate, and hyperglycemia-propofol." | 3.79 | Propofol attenuates renal ischemia-reperfusion injury aggravated by hyperglycemia. ( Jun, JH; Kwak, YL; Lim, BJ; Shim, JK; Yoo, KJ; Yoo, YC, 2013) |
| "To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 3.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
| "During surgery, hyperglycemia was observed under sevoflurane and sevoflurane/buprenorphine anesthesia, but blood glucose levels were relatively stable under propofol and propofol/buprenorphine anesthesia." | 3.75 | The effects of sevoflurane and propofol on glucose metabolism under aerobic conditions in fed rats. ( Kawamura, G; Kitamura, T; Ogawa, M; Sato, K; Yamada, Y, 2009) |
| "Propofol is a widely used anesthetic." | 1.72 | Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions. ( Ding, J; Hou, W; Jiang, H; Lu, L; Shao, J; Sun, Z; Wang, F; Zhao, Y, 2022) |
| "Propofol is a widely used anesthetic drug in clinical settings." | 1.43 | Propofol attenuates high glucose-induced superoxide anion accumulation in human umbilical vein endothelial cells. ( Jiang, H; Wang, J; Zhao, Y; Zhu, M; Zhu, Y, 2016) |
| "Propofol has been reported to improve high glucose-induced endothelial dysfunction." | 1.38 | Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells. ( Chen, J; Tan, Z; Wang, J; Zhu, M, 2012) |
| "Where hypotension was present, the method of and response to treatment was recorded." | 1.36 | A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study. ( Clark, L; Corletto, F; Gould, DJ; Oliver, JA, 2010) |
| "Propofol has been known to suppress glucose metabolism in the brain and possess neuroprotective properties in cerebral ischaemia." | 1.31 | Effects of propofol on lactate accumulation and oedema formation in focal cerebral ischaemia in hyperglycaemic rats. ( Arai, T; Fukuda, K; Inubushi, T; Ishii, H; Morikawa, S; Segawa, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Han, RH | 1 |
| Huang, HM | 1 |
| Han, H | 1 |
| Chen, H | 1 |
| Zeng, F | 1 |
| Xie, X | 2 |
| Liu, DY | 1 |
| Cai, Y | 1 |
| Zhang, LQ | 1 |
| Liu, X | 2 |
| Xia, ZY | 2 |
| Tang, J | 1 |
| Shao, J | 1 |
| Ding, J | 1 |
| Lu, L | 1 |
| Hou, W | 1 |
| Wang, F | 1 |
| Sun, Z | 1 |
| Jiang, H | 2 |
| Zhao, Y | 2 |
| Wu, CC | 1 |
| Hung, CJ | 1 |
| Wang, YY | 1 |
| Lin, SY | 1 |
| Chen, WY | 1 |
| Kuan, YH | 1 |
| Liao, SL | 1 |
| Yang, CP | 1 |
| Chen, CJ | 1 |
| Lemos, SV | 1 |
| Vianna, IG | 1 |
| Castiglia, YM | 2 |
| Golim, MA | 1 |
| Souza, AV | 2 |
| Carvalho, LR | 2 |
| Deffune, E | 2 |
| Nascimento, PD | 1 |
| Módolo, NS | 1 |
| Vianna, PT | 2 |
| Deng, F | 1 |
| Wang, S | 1 |
| Zhang, L | 1 |
| Cai, S | 1 |
| Li, H | 2 |
| Xie, GL | 1 |
| Miao, HL | 1 |
| Yang, C | 1 |
| Xia, Z | 2 |
| Sakata, K | 1 |
| Kito, K | 1 |
| Tanabe, K | 1 |
| Fukuoka, N | 1 |
| Nagase, K | 1 |
| Iida, H | 1 |
| Yoo, YC | 1 |
| Yoo, KJ | 1 |
| Lim, BJ | 1 |
| Jun, JH | 1 |
| Shim, JK | 1 |
| Kwak, YL | 1 |
| Carraretto, AR | 1 |
| Vianna Filho, PT | 1 |
| Golim, Mde A | 1 |
| Xu, J | 1 |
| Irwin, MG | 1 |
| Mao, X | 1 |
| Lei, S | 1 |
| Wong, GT | 1 |
| Hung, V | 1 |
| Cheung, CW | 1 |
| Fang, X | 1 |
| Clanachan, AS | 1 |
| Wang, J | 3 |
| Zhu, Y | 1 |
| Zhu, M | 2 |
| Kitamura, T | 1 |
| Ogawa, M | 1 |
| Kawamura, G | 1 |
| Sato, K | 1 |
| Yamada, Y | 1 |
| Oliver, JA | 1 |
| Clark, L | 1 |
| Corletto, F | 1 |
| Gould, DJ | 1 |
| Chen, J | 1 |
| Tan, Z | 1 |
| Ishii, H | 1 |
| Arai, T | 1 |
| Segawa, H | 1 |
| Morikawa, S | 1 |
| Inubushi, T | 1 |
| Fukuda, K | 1 |
14 other studies available for propofol and Hyperglycemia
| Article | Year |
|---|---|
Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia.
Topics: Animals; Apoptosis; Autophagy; Forkhead Transcription Factors; Hyperglycemia; Hypoxia; Ischemic Post | 2021 |
Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions.
Topics: Cyclooxygenase 2; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Nitric Oxi | 2022 |
Propofol Improved Glucose Tolerance Associated with Increased FGF-21 and GLP-1 Production in Male Sprague-Dawley Rats.
Topics: Animals; Blood Glucose; Disease Models, Animal; Fibroblast Growth Factors; Glucagon-Like Peptide 1; | 2020 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; | 2017 |
Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.
Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caveolin 3; Cell Hypoxia; Cell Line; Cell Survival; Glucos | 2017 |
Propofol But Not Desflurane Maintains Rat Cerebral Arteriolar Responses to Acetylcholine During Acute Hyperglycemia.
Topics: Acetylcholine; Animals; Arterioles; Endothelium, Vascular; Hyperglycemia; Propofol; Rats; Rats, Spra | 2021 |
Propofol attenuates renal ischemia-reperfusion injury aggravated by hyperglycemia.
Topics: Anesthetics, Intravenous; Animals; Antioxidants; Comorbidity; Disease Models, Animal; Etomidate; Hyp | 2013 |
Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
Topics: Acute Disease; Anesthesia; Anesthetics; Animals; Cell Survival; Creatinine; Flow Cytometry; Hypergly | 2013 |
Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats.
Topics: Activating Transcription Factor 3; Animals; Antioxidants; Apoptosis; Cardiomegaly; Diabetes Mellitus | 2014 |
Propofol attenuates high glucose-induced superoxide anion accumulation in human umbilical vein endothelial cells.
Topics: Antioxidants; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Glucose; Human Umbilical Vein | 2016 |
The effects of sevoflurane and propofol on glucose metabolism under aerobic conditions in fed rats.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Blood Glucose; Buprenorphine; Colostomy; Dose | 2009 |
A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study.
Topics: Acepromazine; Anesthesia, Intravenous; Animals; Bradycardia; Cataract; Diabetes Mellitus; Dog Diseas | 2010 |
Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells.
Topics: Anesthetics, Intravenous; Antioxidants; Biopterins; Blotting, Western; Cells, Cultured; Chromatograp | 2012 |
Effects of propofol on lactate accumulation and oedema formation in focal cerebral ischaemia in hyperglycaemic rats.
Topics: Anesthetics, Intravenous; Animals; Brain; Brain Edema; Brain Ischemia; Hyperglycemia; Lactic Acid; M | 2002 |