acetoacetic acid has been researched along with Hyperglycemia in 15 studies
acetoacetic acid : A 3-oxo monocarboxylic acid that is butyric acid bearing a 3-oxo substituent.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Erythrocytes were washed, suspended in buffers containing 5 mM glucose (simulates euglycemia) or 25 mM glucose (simulates hyperglycemia), and incubated with acetone (5 and 10 mM, acetoacetate (5 and 10 mM), or beta-hydroxybutyrate (5 and 25 mM) for 24 hours at 37 C." | 3.69 | In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. ( Christopher, MM; Fallin, CW, 1996) |
| "Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal." | 1.39 | Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013) |
| "Type 1 diabetes is associated with elevated levels of blood PAI-1 and cardiovascular disease (CVD) incidence." | 1.37 | Effects of high glucose and ketosis (acetoacetate, ss-hydroxybutyrate) on PAI-1 secretion in human umbilical vascular endothelial cells. ( Jain, SK; Velusamy, T, 2011) |
| "To investigate in vitro effects of ketosis and hyperglycemia on feline erythrocyte Heinz body formation, reduced glutathione (GSH) concentration, and D- and L-lactate production, and to identify potential metabolic mechanisms of oxidative stress in diabetic cats." | 1.29 | In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. ( Christopher, MM; Fallin, CW, 1996) |
| "Neither high glucose concentration nor ketosis had direct effects on Heinz body formation or GSH values." | 1.29 | In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. ( Christopher, MM; Fallin, CW, 1996) |
| "High glucose concentration and ketosis do not account directly for oxidative damage and glyoxalase induction in feline erythrocytes in vitro, although high concentrations of beta-hydroxybutyrate may stimulate D-lactate formation." | 1.29 | In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. ( Christopher, MM; Fallin, CW, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Polidori, D | 1 |
| Iijima, H | 1 |
| Goda, M | 1 |
| Maruyama, N | 1 |
| Inagaki, N | 1 |
| Crawford, PA | 1 |
| Mahendran, Y | 1 |
| Vangipurapu, J | 1 |
| Cederberg, H | 1 |
| Stancáková, A | 1 |
| Pihlajamäki, J | 1 |
| Soininen, P | 1 |
| Kangas, AJ | 1 |
| Paananen, J | 1 |
| Civelek, M | 1 |
| Saleem, NK | 1 |
| Pajukanta, P | 1 |
| Lusis, AJ | 1 |
| Bonnycastle, LL | 1 |
| Morken, MA | 1 |
| Collins, FS | 1 |
| Mohlke, KL | 1 |
| Boehnke, M | 1 |
| Ala-Korpela, M | 1 |
| Kuusisto, J | 1 |
| Laakso, M | 1 |
| Keltanen, T | 1 |
| Sajantila, A | 1 |
| Palo, JU | 1 |
| Partanen, T | 1 |
| Valonen, T | 1 |
| Lindroos, K | 1 |
| Velusamy, T | 1 |
| Jain, SK | 1 |
| Harano, Y | 1 |
| NATH, MC | 1 |
| CHAKRABARTI, CH | 1 |
| NAYUDU, SG | 1 |
| Khan, AS | 1 |
| Talbot, JA | 1 |
| Tieszen, KL | 1 |
| Gardener, EA | 1 |
| Gibson, JM | 1 |
| New, JP | 1 |
| Ramakrishnan, R | 1 |
| Sheeladevi, R | 1 |
| Suthanthirarajan, N | 1 |
| Namasivayam, A | 1 |
| Everett-Grueter, C | 1 |
| Edgerton, DS | 1 |
| Donahue, EP | 1 |
| Vaughan, S | 1 |
| Chu, CA | 1 |
| Sindelar, DK | 1 |
| Cherrington, AD | 1 |
| Taboulet, P | 1 |
| Deconinck, N | 1 |
| Thurel, A | 1 |
| Haas, L | 1 |
| Manamani, J | 1 |
| Porcher, R | 1 |
| Schmit, C | 1 |
| Fontaine, JP | 1 |
| Gautier, JF | 1 |
| Fallin, CW | 1 |
| Christopher, MM | 1 |
| Rodríguez, T | 1 |
| Busquets, S | 1 |
| Alvarez, B | 1 |
| Agell, N | 1 |
| Lpez-Soriano, FJ | 1 |
| Argilś, JM | 1 |
| Møller, N | 1 |
| Jørgensen, JO | 1 |
| Møller, J | 1 |
| Orskov, L | 1 |
| Pørksen, N | 1 |
| Alberti, KG | 1 |
| Schmitz, O | 1 |
| Baron, AD | 1 |
| Brechtel, G | 1 |
| Edelman, SV | 1 |
| Zusman, I | 1 |
| Ornoy, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'[NCT05225467] | 58 participants (Actual) | Observational [Patient Registry] | 2022-03-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetoacetic acid and Hyperglycemia
| Article | Year |
|---|---|
[Blood level of ketone bodies and its clinical significance].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2002 |
1 trial available for acetoacetic acid and Hyperglycemia
| Article | Year |
|---|---|
Intra- and inter-subject variability for increases in serum ketone bodies in patients with type 2 diabetes treated with the sodium glucose co-transporter 2 inhibitor canagliflozin.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biological Variation, Population; Blood Glucose; Canagliflozin | 2018 |
13 other studies available for acetoacetic acid and Hyperglycemia
| Article | Year |
|---|---|
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Area Under Curve; Biomarkers; Blood Glucose; Diabetes Mellitus | 2013 |
Assessment of Traub formula and ketone bodies in cause of death investigations.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl | 2013 |
Effects of high glucose and ketosis (acetoacetate, ss-hydroxybutyrate) on PAI-1 secretion in human umbilical vascular endothelial cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Ketoacido | 2011 |
Effect of methionine and casein on acetoacetate induced hyperglycemia.
Topics: Acetoacetates; Animals; Caseins; Hyperglycemia; Methionine; Rats | 1955 |
Evaluation of a bedside blood ketone sensor: the effects of acidosis, hyperglycaemia and acetoacetate on sensor performance.
Topics: Acetoacetates; Acidosis; Biosensing Techniques; Blood Glucose; Blood Glucose Self-Monitoring; Diabet | 2004 |
An acute hyperglycemia or acidosis-induced changes of indolamines level correlates with PKC-alpha expression in rat brain.
Topics: Acetoacetates; Ammonium Chloride; Animals; Brain; Brain Chemistry; Diabetes Complications; Diabetic | 2005 |
The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Blood Glucose; Cyclic AMP; Dogs; Fat Emu | 2006 |
Correlation between urine ketones (acetoacetate) and capillary blood ketones (3-beta-hydroxybutyrate) in hyperglycaemic patients.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Hy | 2007 |
In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Cat Diseases; Cats; Erythrocytes; Female; Gl | 1996 |
Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adipose Tissue; Animals; Body Weight; Diabetes Mellitus, Exper | 1998 |
Lack of effects of hyperglycemia on the disposal of 3-hydroxybutyrate in insulin-dependent diabetic patients.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, | 1990 |
Effects of free fatty acids and ketone bodies on in vivo non-insulin-mediated glucose utilization and production in humans.
Topics: Acetoacetates; Adult; Fatty Acids, Nonesterified; Glucose; Humans; Hyperglycemia; Insulin; Ketone Bo | 1989 |
Effects of hyperglycemia and ketone bodies on the in vitro development of early somite rate embryos.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Congenital Abnormalities; Cu | 1987 |