risperidone has been researched along with Hyperglycemia in 26 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to explore the association of genetic polymorphism of genes related to pharmacokinetics or pharmacodynamics with insulin resistance in children and adolescents with autism spectrum disorder (ASD) and treated with risperidone." | 7.88 | Pharmacogenetics of Risperidone-Induced Insulin Resistance in Children and Adolescents with Autism Spectrum Disorder. ( Chamkrachangpada, B; Hongkaew, Y; Limsila, P; Ngamsamut, N; Nuntamool, N; Puangpetch, A; Srisawasdi, P; Sukasem, C; Vanwong, N, 2018) |
| "A 35-year-old woman, diagnosed as schizophrenia and treated with olanzapine for nearly 30 months, consulted our department because of severe hyperglycemia." | 7.76 | Severe hyperglycemia induced by olanzapine was improved with a recovery of insulin secretion after switching to risperidone and introducing insulin therapy. ( Nagamine, T; Nakamura, M, 2010) |
| "Pharmacovigilance survey of spontaneously reported adverse events in risperidone-treated patients, with reports of haloperidol-associated hyperglycemia used as a control." | 7.72 | Risperidone-associated diabetes mellitus: a pharmacovigilance study. ( Cross, JT; Doraiswamy, PM; Koller, EA; Schneider, BS, 2003) |
| " The authors' goal was to assess the effects of clozapine, olanzapine, risperidone, and haloperidol on glucose and cholesterol levels in hospitalized patients with schizophrenia or schizoaffective disorder during a randomized double-blind 14-week trial." | 5.10 | Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics. ( Chakos, M; Citrome, L; Cooper, TB; Czobor, P; Lieberman, JA; Lindenmayer, JP; McEvoy, JP; Sheitman, B; Volavka, J, 2003) |
| "The purpose of this study was to explore the association of genetic polymorphism of genes related to pharmacokinetics or pharmacodynamics with insulin resistance in children and adolescents with autism spectrum disorder (ASD) and treated with risperidone." | 3.88 | Pharmacogenetics of Risperidone-Induced Insulin Resistance in Children and Adolescents with Autism Spectrum Disorder. ( Chamkrachangpada, B; Hongkaew, Y; Limsila, P; Ngamsamut, N; Nuntamool, N; Puangpetch, A; Srisawasdi, P; Sukasem, C; Vanwong, N, 2018) |
| " Hospitalizations for hyperglycemic emergencies (hyperglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic state) were compared between new users of risperidone (reference), and new users of olanzapine, other atypical antipsychotics, and typical antipsychotics." | 3.80 | Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data. ( Alessi-Severini, S; Austin, PC; Blackburn, DF; Blais, L; Bresee, L; Filion, KB; Kawasumi, Y; Kurdyak, P; Lipscombe, LL; Paterson, JM; Platt, RW; Tamim, H, 2014) |
| "Patients with schizophrenia receive medication to alleviate various symptoms, but some efficacious second generation antipsychotics, particularly olanzapine, can cause obesity, dyslipidemia, and diabetes mellitus." | 3.79 | The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation. ( Harding, H; Mori, K; Nadanaka, S; Nagamine, T; Okada, T; Ozasa, R; Ron, D; Zyryanova, A, 2013) |
| "A 35-year-old woman, diagnosed as schizophrenia and treated with olanzapine for nearly 30 months, consulted our department because of severe hyperglycemia." | 3.76 | Severe hyperglycemia induced by olanzapine was improved with a recovery of insulin secretion after switching to risperidone and introducing insulin therapy. ( Nagamine, T; Nakamura, M, 2010) |
| "The risk of the appearance of diabetes mellitus in patients treated with olanzapine is twice as high as that in patients treated with risperidone, and the risk in patients treated with clozapine is nearly triple as high as that found in patients treated with risperidone." | 3.73 | [Therapy with antipsychotic drugs as a risk factor for diabetes in schizophrenia: a case-control study]. ( Burón, JA; Gómez-de-la-Cámara, A; Ledesma, F; Martínez-Junquera, G; Rodríguez-Morales, A; Rubio, G, 2006) |
| "Pharmacovigilance survey of spontaneously reported adverse events in risperidone-treated patients, with reports of haloperidol-associated hyperglycemia used as a control." | 3.72 | Risperidone-associated diabetes mellitus: a pharmacovigilance study. ( Cross, JT; Doraiswamy, PM; Koller, EA; Schneider, BS, 2003) |
| "To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs." | 3.71 | Glucose intolerance with atypical antipsychotics. ( Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M, 2002) |
| "RLAI and OP show good short- and long-term safety when treating patients with schizophrenia, with uncommon discontinuation due to adverse effects." | 2.46 | Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review. ( Cañas, F; Möller, HJ, 2010) |
| "Olanzapine (6 mg/kg) treatment significantly altered glucose and lipid homeostasis which was further accompanied by elevated levels of proinflammatory cytokines, ghrelin and leptin." | 1.51 | Modeling of antipsychotic-induced metabolic alterations in mice: An experimental approach precluding psychosis as a predisposing factor. ( Bansal, Y; Kuhad, A; Medhi, B; Saroj, P; Singh, R; Sodhi, RK, 2019) |
| "Hyperglycemia is associated with several common neurological syndromes." | 1.37 | Permanent haemichorea associated with transient hyperglycemia. ( Arnason, T; Savedia-Cayabyab, S; Senior, P; Slabu, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (53.85) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sukasem, C | 1 |
| Vanwong, N | 1 |
| Srisawasdi, P | 1 |
| Ngamsamut, N | 1 |
| Nuntamool, N | 1 |
| Hongkaew, Y | 1 |
| Puangpetch, A | 1 |
| Chamkrachangpada, B | 1 |
| Limsila, P | 1 |
| Skonieczna-Żydecka, K | 1 |
| Łoniewski, I | 1 |
| Misera, A | 1 |
| Stachowska, E | 1 |
| Maciejewska, D | 1 |
| Marlicz, W | 1 |
| Galling, B | 1 |
| Singh, R | 1 |
| Bansal, Y | 1 |
| Sodhi, RK | 1 |
| Saroj, P | 1 |
| Medhi, B | 1 |
| Kuhad, A | 1 |
| Vale, TC | 1 |
| Freitas, Dda S | 1 |
| Maciel, RO | 1 |
| Miranda, EC | 1 |
| Cardoso, F | 1 |
| Ozasa, R | 1 |
| Okada, T | 1 |
| Nadanaka, S | 1 |
| Nagamine, T | 2 |
| Zyryanova, A | 1 |
| Harding, H | 1 |
| Ron, D | 1 |
| Mori, K | 1 |
| Lipscombe, LL | 1 |
| Austin, PC | 1 |
| Alessi-Severini, S | 1 |
| Blackburn, DF | 1 |
| Blais, L | 1 |
| Bresee, L | 1 |
| Filion, KB | 1 |
| Kawasumi, Y | 1 |
| Kurdyak, P | 1 |
| Platt, RW | 1 |
| Tamim, H | 1 |
| Paterson, JM | 1 |
| Cañas, F | 1 |
| Möller, HJ | 1 |
| Nakamura, M | 1 |
| Adeneye, AA | 1 |
| Agbaje, EO | 1 |
| Olagunju, JA | 1 |
| Létourneau, G | 1 |
| Abdel-Baki, A | 1 |
| Dubreucq, S | 1 |
| Mahone, M | 1 |
| Granger, B | 1 |
| Slabu, H | 1 |
| Savedia-Cayabyab, S | 1 |
| Senior, P | 1 |
| Arnason, T | 1 |
| Stern, AP | 1 |
| Trieu, ML | 1 |
| Hedenmalm, K | 1 |
| Hägg, S | 1 |
| Ståhl, M | 1 |
| Mortimer, O | 1 |
| Spigset, O | 1 |
| Lindenmayer, JP | 1 |
| Czobor, P | 1 |
| Volavka, J | 1 |
| Citrome, L | 1 |
| Sheitman, B | 1 |
| McEvoy, JP | 1 |
| Cooper, TB | 1 |
| Chakos, M | 1 |
| Lieberman, JA | 1 |
| Gupta, S | 1 |
| Koller, EA | 1 |
| Cross, JT | 1 |
| Doraiswamy, PM | 1 |
| Schneider, BS | 1 |
| Clark, C | 1 |
| Burge, MR | 1 |
| Ananth, J | 1 |
| Johnson, KM | 1 |
| Levander, EM | 1 |
| Harry, JL | 1 |
| Filaković, P | 1 |
| Laufer, D | 1 |
| Radanović-Grgurić, L | 1 |
| Koić, O | 1 |
| Fijacko, M | 1 |
| Durković, M | 1 |
| Wu, PL | 1 |
| Lane, HY | 1 |
| Su, KP | 1 |
| Rubio, G | 1 |
| Gómez-de-la-Cámara, A | 1 |
| Ledesma, F | 1 |
| Burón, JA | 1 |
| Rodríguez-Morales, A | 1 |
| Martínez-Junquera, G | 1 |
| Duncan, E | 1 |
| Dunlop, BW | 1 |
| Boshoven, W | 1 |
| Woolson, SL | 1 |
| Hamer, RM | 1 |
| Phillips, LS | 1 |
| Hardy, TA | 1 |
| Meyers, AL | 1 |
| Yu, J | 1 |
| Shankar, SS | 1 |
| Steinberg, HO | 2 |
| Porksen, NK | 1 |
| Ardizzone, TD | 1 |
| Bradley, RJ | 1 |
| Freeman, AM | 1 |
| Dwyer, DS | 1 |
| Mallya, A | 1 |
| Chawla, P | 1 |
| Boyer, SK | 1 |
| DeRosear, L | 1 |
| Sowell, MO | 1 |
| Mukhopadhyay, N | 1 |
| Cavazzoni, P | 1 |
| Shankar, S | 1 |
| Breier, A | 1 |
| Beasley, CM | 1 |
| Dananberg, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Community-based, Family Navigator Intervention to Improve Cardiometabolic Health of Medicaid-insured Youth Identified Through an Antipsychotic Medication Preauthorization Program[NCT02877823] | 302 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| Atypical Antipsychotics and Hyperglycemic Emergencies: Multicentre, Retrospective Cohort Study of Administrative Data[NCT02582736] | 725,489 participants (Actual) | Observational | 2012-04-30 | Completed | |||
| Outcome Evaluation of Solutions for Wellness and Team Solutions Program in Patients With Severe Mental Illness[NCT00661869] | 295 participants (Actual) | Interventional | 2006-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for risperidone and Hyperglycemia
| Article | Year |
|---|---|
Second-generation antipsychotics and metabolism alterations: a systematic review of the role of the gut microbiome.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Gastrointestinal Microbiome; Humans; Hyperglycemia; | 2019 |
Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review.
Topics: Administration, Oral; Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Dyslipidem | 2010 |
Safety in treating bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Melli | 2003 |
Diabetes mellitus associated with atypical anti-psychotic medications.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clozap | 2003 |
4 trials available for risperidone and Hyperglycemia
| Article | Year |
|---|---|
Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cholesterol; Clozapine; Double-Bl | 2003 |
Newer antipsychotics and glucose metabolism: a comparison between olanzapine and risperidone.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gluc | 2005 |
Acute insulin response and beta-cell compensation in normal subjects treated with olanzapine or risperidone for 2 weeks.
Topics: Benzodiazepines; Blood Glucose; C-Peptide; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; | 2007 |
Hyperglycemic clamp assessment of insulin secretory responses in normal subjects treated with olanzapine, risperidone, or placebo.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Female; Glucose Clamp Technique; Huma | 2002 |
18 other studies available for risperidone and Hyperglycemia
| Article | Year |
|---|---|
Pharmacogenetics of Risperidone-Induced Insulin Resistance in Children and Adolescents with Autism Spectrum Disorder.
Topics: Adolescent; Adult; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; Autism Spect | 2018 |
Modeling of antipsychotic-induced metabolic alterations in mice: An experimental approach precluding psychosis as a predisposing factor.
Topics: Animals; Antipsychotic Agents; Body Weight; Female; Ghrelin; Hyperglycemia; Leptin; Mice; Mice, Inbr | 2019 |
Teaching Video NeuroImages: hemichorea-hemiballismus secondary to nonketotic hyperglycemia.
Topics: Antipsychotic Agents; Brain; Chorea; Diabetes Mellitus, Type 2; Dyskinesias; Female; Humans; Hypergl | 2013 |
The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation.
Topics: Animals; Antipsychotic Agents; Apoptosis; Benzodiazepines; Cell Line; Cricetinae; Diabetes Mellitus; | 2013 |
Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Diabetes Complications; Female; Huma | 2014 |
Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Diabetes Complications; Female; Huma | 2014 |
Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Diabetes Complications; Female; Huma | 2014 |
Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Diabetes Complications; Female; Huma | 2014 |
Severe hyperglycemia induced by olanzapine was improved with a recovery of insulin secretion after switching to risperidone and introducing insulin therapy.
Topics: Adult; Benzodiazepines; Drug Substitution; Female; Humans; Hyperglycemia; Insulin; Insulin Secretion | 2010 |
Metformin: an effective attenuator of risperidone-induced insulin resistance hyperglycemia and dyslipidemia in rats.
Topics: Animals; Antipsychotic Agents; Blood Glucose; Disease Models, Animal; Dyslipidemias; Glyburide; Huma | 2011 |
Hyperosmolar hyperglycemic state associated with ziprasidone treatment: a case report.
Topics: Adult; Antipsychotic Agents; Humans; Hyperglycemia; Male; Osmolar Concentration; Piperazines; Risper | 2011 |
Permanent haemichorea associated with transient hyperglycemia.
Topics: Chorea; Diagnosis, Differential; Dopamine Antagonists; Humans; Hyperglycemia; Hypoglycemic Agents; M | 2011 |
A case of antipsychotic-induced hyperglycemia in a child with insulin dependent diabetes mellitus.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders; | 2012 |
Glucose intolerance with atypical antipsychotics.
Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlor | 2002 |
Risperidone-associated diabetes mellitus: a pharmacovigilance study.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An | 2003 |
Diabetic ketoacidosis, neuroleptic malignant syndrome, and myocardial infarction in a patient taking risperidone and lithium carbonate.
Topics: Antipsychotic Agents; Diabetic Ketoacidosis; Drug Therapy, Combination; Humans; Hyperglycemia; Lithi | 2004 |
Risperidone alternative for a schizophrenic patient with olanzapine-exacerbated diabetic mellitus.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Diabetes Mellitus, Type 2; Disease Progression; Humans | 2006 |
[Therapy with antipsychotic drugs as a risk factor for diabetes in schizophrenia: a case-control study].
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Clozapi | 2006 |
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population.
Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphe | 2007 |
Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine.
Topics: Animals; Antimetabolites; Antipsychotic Agents; Biological Transport; Clozapine; Deoxyglucose; Dose- | 2001 |
Resolution of hyperglycemia on risperidone discontinuation: a case report.
Topics: Adult; Antipsychotic Agents; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia | 2002 |