Page last updated: 2024-10-21

phenytoin and Hyperglycemia

phenytoin has been researched along with Hyperglycemia in 39 studies

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"A case of diabetic ketoacidosis in a 64-year-old black woman with maturity-onset diabetes receiving phenytoin for a seizure disorder is reported."7.66Phenytoin-induced hyperglycemia. ( Carter, BL; Mandel, MD; Small, RE; Starkman, MT, 1981)
"A case of diabetic ketoacidosis in a 64-year-old black woman with maturity-onset diabetes receiving phenytoin for a seizure disorder is reported."3.66Phenytoin-induced hyperglycemia. ( Carter, BL; Mandel, MD; Small, RE; Starkman, MT, 1981)
"Phenytoin is a known human teratogen with unknown etiology."1.62The effect of phenytoin on embryonic heart rate in Vivo. ( Ababneh, D; Abela, D; Farrell, E; Hegedus, E; Howe, AM; Ritchie, HE, 2021)
"Occipital lobe seizures caused by nonketotic hyperglycemia (NKH) have been reported in only a few cases and are not fully characterized."1.36Occipital lobe seizures related to marked elevation of hemoglobin A1C: report of two cases. ( Chang, MH; Hsieh, PF; Hung, WL; Lee, YC, 2010)
"Propranolol pretreatment (5 mg/kg) does not affect the DPH-induced changes in blood glucose, plasma insulin and plasma glucagon."1.26Studies on the hyperglycemic effect of diphenylhydantoin in normal golden hamsters. ( Lefebvre, PJ; Luyckx, AS; Tamburrano, S, 1976)
"Glycogen was depleted only by amphetamine-like compounds or by bemegride-induced convulsions."1.25Physiological and drug-induced changes in the glycogen content of mouse brain. ( Hutchins, DA; Rogers, KJ, 1970)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199033 (84.62)18.7374
1990's3 (7.69)18.2507
2000's0 (0.00)29.6817
2010's2 (5.13)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Ritchie, HE1
Abela, D1
Ababneh, D1
Howe, AM1
Farrell, E1
Hegedus, E1
Witthayapraphakorn, L1
Srilanchakon, K1
Sahakitrungruang, T1
Wacharasindhu, S1
Supornsilchai, V1
Hung, WL1
Hsieh, PF1
Lee, YC1
Chang, MH1
Dahl, JR1
Gunnarsson, R1
Collste, H1
Lundgren, G1
Ostman, J1
Groth, CG1
Kutt, H1
Solomon, GE1
Boquist, L1
Bäckman, AM1
Strömberg, C1
Aquino, A1
Gabor, AJ1
Carter, BL1
Small, RE1
Mandel, MD1
Starkman, MT1
Hazard, J1
Perlemuter, L1
Colombo, JL1
Lohff, MR1
Sanbar, SS2
Tamburrano, S1
Luyckx, AS1
Lefebvre, PJ1
Edwardson, JM1
Dean, PM1
Takebe, K1
Onuma, T1
al-Rubeaan, K1
Ryan, EA1
Young, B1
Ott, L1
Dempsey, R1
Haack, D1
Tibbs, P1
Espósito Avella, M1
Dávila, L1
Bravo, C1
Castleden, CM1
Richens, A1
Gharib, H1
Munoz, JM1
Vaisrub, S1
Esposito-Avella, M1
Mennear, JH2
Gossel, TA1
Kim, CB1
Johnson, WW1
MacMillan, DR1
Strandjord, RE1
Johannessen, SI1
Levin, SR1
Booker, J1
Smith, DF1
Grodsky, GM1
Said, DM1
Fraga, JR1
Reichelderfer, TE1
Treasure, T1
Toseland, PA1
Holcomb, R1
Lynn, R1
Harvey, B1
Sweetman, BJ1
Gerber, N1
Buckley, RE1
Evans, CC1
Littler, WA1
Meade, JB1
Hutchins, DA1
Rogers, KJ1
Fariss, BL2
Lutcher, CL2
Krupin, T1
Podos, SM1
Becker, B1
Goldberg, EM1
Peters, BH1
Samaan, NA1
Millichap, JG1
Klein, JP1

Reviews

1 review available for phenytoin and Hyperglycemia

ArticleYear
Phenytoin: relevant side effects.
    Advances in neurology, 1980, Volume: 27

    Topics: Animals; Blood Coagulation; Bone and Bones; Calcium; Connective Tissue Diseases; Drug Hypersensitivi

1980

Other Studies

38 other studies available for phenytoin and Hyperglycemia

ArticleYear
The effect of phenytoin on embryonic heart rate in Vivo.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 106

    Topics: Abnormalities, Drug-Induced; Animals; Female; Heart; Heart Rate; Hyperglycemia; Hypoxia; Phenytoin;

2021
Phenytoin-induced dysglycemia in a child.
    Pediatrics international : official journal of the Japan Pediatric Society, 2017, Volume: 59, Issue:9

    Topics: Anticonvulsants; Humans; Hyperglycemia; Hypoglycemia; Infant; Male; Phenytoin

2017
Occipital lobe seizures related to marked elevation of hemoglobin A1C: report of two cases.
    Seizure, 2010, Volume: 19, Issue:6

    Topics: Acidosis; Adult; Anticonvulsants; Brain; Electroencephalography; Female; Glycated Hemoglobin; Humans

2010
Diphenylhydantoin toxic psychosis with associated hyperglycemia.
    California medicine, 1967, Volume: 107, Issue:4

    Topics: Glycosuria; Humans; Hyperglycemia; Male; Middle Aged; Phenytoin; Psychoses, Substance-Induced

1967
Observations on B-cell function after segmental pancreatic allotransplantation in diabetic patients.
    Hormone and metabolic research. Supplement series, 1983, Issue:13

    Topics: Adrenal Cortex Hormones; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Humans;

1983
Hyperglycemia produced in mice by administration of acetazolamide and diphenylhydantoin.
    European journal of pharmacology, 1980, Jun-27, Volume: 64, Issue:4

    Topics: Acetazolamide; Animals; Blood Glucose; Drug Interactions; Hydroxymercuribenzoates; Hyperglycemia; In

1980
Movement-induced seizures in nonketotic hyperglycemia.
    Neurology, 1980, Volume: 30, Issue:6

    Topics: Aged; Humans; Hyperglycemia; Male; Middle Aged; Movement; Phenytoin; Seizures

1980
Phenytoin-induced hyperglycemia.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:10

    Topics: Acidosis; Diabetes Complications; Female; Humans; Hyperglycemia; Middle Aged; Phenytoin; Seizures

1981
[Action of phenytoin on glycoregulation].
    La Nouvelle presse medicale, 1975, Sep-27, Volume: 4, Issue:31

    Topics: Adenoma, Islet Cell; Adolescent; Animals; Blood Pressure; Child; Child, Preschool; Depression, Chemi

1975
Phenytoin and hyperglycemic complex.
    The Nebraska medical journal, 1979, Volume: 64, Issue:5

    Topics: Dose-Response Relationship, Drug; Humans; Hyperglycemia; Infant; Infant, Newborn; Infant, Premature,

1979
Metabolic and hemodynamic effects of diphenylhydantoin.
    The Journal of the Oklahoma State Medical Association, 1975, Volume: 68, Issue:9

    Topics: Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Glucose; Hemodynamics; Hyperglycem

1975
Studies on the hyperglycemic effect of diphenylhydantoin in normal golden hamsters.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: Suppl 6

    Topics: Animals; Blood Glucose; Cricetinae; Glucagon; Hyperglycemia; Insulin; Male; Phentolamine; Phenytoin;

1976
Inhibition of alloxan-induced hyperglycaemia by compounds of similar molecular structure.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Allantoin; Alloxan; Animals; Barbiturates; Blood Glucose; Caffeine; Ethosuximide; Hyperglycemia; Ino

1992
[Abnormal glucose tolerance induced by drugs and chemicals].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Adrenergic beta-Antagonists; Asparaginase; Calcium Channel Blockers; Contraceptives, Oral; Cyclospor

1991
Phenytoin-induced insulin insensitivity.
    Diabetic medicine : a journal of the British Diabetic Association, 1991, Volume: 8, Issue:10

    Topics: Aged; Aged, 80 and over; C-Peptide; Coronary Artery Bypass; Coronary Disease; Epilepsies, Partial; H

1991
Relationship between admission hyperglycemia and neurologic outcome of severely brain-injured patients.
    Annals of surgery, 1989, Volume: 210, Issue:4

    Topics: Analysis of Variance; Blood Glucose; Brain Injuries; Dexamethasone; Follow-Up Studies; Humans; Hyper

1989
[Interaction of cadmium, diphenylhydantoin and chlorpromazine: their effect in the metabolism of carbohydrates in mice].
    Revista medica de Panama, 1985, Volume: 10, Issue:3

    Topics: Animals; Cadmium; Carbohydrate Metabolism; Chlorpromazine; Drug Interactions; Glucose Tolerance Test

1985
Letter: Chronic phenytoin therapy and carbohydrate tolerance.
    Lancet (London, England), 1973, Oct-27, Volume: 2, Issue:7835

    Topics: Adolescent; Adult; Child; Epilepsy; Glucose Tolerance Test; Humans; Hyperglycemia; Pancreas; Phenyto

1973
Endocrine manifestations of diphenylhydantoin therapy.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Alkaline Phosphatase; Blood Glucose; End

1974
Diphenylhydantoin and insulin-secreting tumors.
    JAMA, 1973, Jan-29, Volume: 223, Issue:5

    Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; Insulin; Insulin Antagonists; Insulin Secretion; Pancrea

1973
Studies on the protective effect of diphenylhydantoin against alloxan diabetes in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:1

    Topics: Alloxan; Animals; Binding, Competitive; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Hyp

1973
Interactions between diphenylhydantoin and tolbutamide in mice.
    Toxicology and applied pharmacology, 1973, Volume: 24, Issue:2

    Topics: Adrenal Glands; Animals; Blood Glucose; Carbohydrate Metabolism; Drug Interactions; Electroshock; Ep

1973
Hyperglycemic nonketotic coma in a postpancreatectomy diabetic infant.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:5

    Topics: Diabetes Mellitus, Type 1; Glucocorticoids; Humans; Hyperglycemia; Hypoglycemia; Infant; Infant, New

1973
[Can phenytoin cause hyperglycemia?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Nov-30, Volume: 93, Issue:33

    Topics: Animals; Depression, Chemical; Dogs; Humans; Hyperglycemia; Insulin; Insulin Secretion; Phenytoin; R

1973
Inhibition of insulin secretion by diphenylhydantoin in the isolated perfused pancreas.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:3

    Topics: Animals; Depression, Chemical; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secreti

1970
Hyperbglycemia associated with diphenylhydantoin (Dilantin) intoxication.
    The Medical annals of the District of Columbia, 1968, Volume: 37, Issue:3

    Topics: Child, Preschool; Epilepsy, Tonic-Clonic; Glucose Tolerance Test; Glycosuria; Humans; Hyperglycemia;

1968
Hyperglycaemia due to phenytoin toxicity.
    Archives of disease in childhood, 1971, Volume: 46, Issue:248

    Topics: Child; Epilepsy, Tonic-Clonic; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Male; Phenyto

1971
Intoxication with 5,5-diphenylhydantoin (Dilantin): clinical features, blood levels, urinary metabolites, and metabolic changes in a child.
    The Journal of pediatrics, 1972, Volume: 80, Issue:4

    Topics: Ataxia; Child, Preschool; Glucuronates; Half-Life; Humans; Hyperglycemia; Insulin; Male; Movement Di

1972
Diphenylhydantoin in the treatment of duodenal ulcer.
    JAMA, 1972, Jan-24, Volume: 219, Issue:4

    Topics: Diabetes Mellitus; Duodenal Ulcer; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretio

1972
Hyperosmolar hyperglycaemic non-ketotic diabetic coma complicating open heart surgery.
    British heart journal, 1972, Volume: 34, Issue:10

    Topics: Autopsy; Blood; Diabetic Coma; Female; Heart; Humans; Hyperglycemia; Insulin; Middle Aged; Mitral Va

1972
Physiological and drug-induced changes in the glycogen content of mouse brain.
    British journal of pharmacology, 1970, Volume: 39, Issue:1

    Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circad

1970
Diphenylhydantoin-induced hyperglycemia and impaired insulin release. Effect of dosage.
    Diabetes, 1971, Volume: 20, Issue:3

    Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secret

1971
Diphenylhdantoin-induced hyperglycemia and impaired insulin release. Effect of dosage.
    Diabetes, 1971, Volume: 20, Issue:3

    Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secret

1971
Effect of diphenylhydantoin on dexamethasone suppression of plasma cortisol in primary open-angle glaucoma.
    American journal of ophthalmology, 1971, Volume: 71, Issue:5

    Topics: Depression, Chemical; Dexamethasone; Feedback; Fundus Oculi; Glaucoma; Glucose Tolerance Test; Human

1971
Hyperglycemic, nonketotic coma following administration of Dilantin (Diphenylhydantoin).
    Diabetes, 1969, Volume: 18, Issue:2

    Topics: Animals; Blood Glucose; Blood Pressure; Coma; Dogs; Fatty Acids, Nonesterified; Humans; Hyperglycemi

1969
Hyperglycemia with relative hypoinsulinemia in diphenylhydantoin toxicity.
    The New England journal of medicine, 1969, Jul-10, Volume: 281, Issue:2

    Topics: Adolescent; Arginine; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia;

1969
Hyperglycemic effect of diphenylhydantoin.
    The New England journal of medicine, 1969, Aug-21, Volume: 281, Issue:8

    Topics: Child; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Phenytoin

1969
Diphenylhydantoin intoxication associated with hyperglycemia.
    The Journal of pediatrics, 1966, Volume: 69, Issue:3

    Topics: Humans; Hyperglycemia; Infant; Male; Phenobarbital; Phenytoin

1966