swerchirin has been researched along with Hyperglycemia* in 1 studies
1 other study(ies) available for swerchirin and Hyperglycemia
| Article | Year |
|---|---|
Swerchirin induced blood sugar lowering of streptozotocin treated hyperglycemic rats.
Effect of Swerchirin (1:8 dihydroxy 3:5 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied. Streptozotocin was administered in citrate buffer (pH-4.5) intravenously / 35 and 65 mg/kg body wt to Charles Foster strain albino rats. Swerchirin (50 mg/kg, po) suspended in gum acacia was fed through cannula to the above rats and to a group of healthy rats. Blood sugar estimated at 0, 1, 3 and 7 hr after, indicated a very significant lowering in healthy and streptozotocin (35 mg/kg iv) but not in streptozotocin (65 mg/kg) treated rats. Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Male; Rats; Streptozocin; Xanthenes; Xanthones | 1991 |