isoflurane has been researched along with Hyperglycemia in 23 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane anesthesia is reported to induce insulin resistance (IR) in the peripheral tissues." | 7.96 | Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice. ( Fang, X; Gu, X; Ma, Z; Wu, H; Xia, T; Xu, F; Zhao, X, 2020) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 7.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 7.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
| "Our results suggest that the metabolic stress of hyperglycemia can impair isoflurane-induced vascular K(ATP) channel activity mediated by excessive activation of PKC." | 7.74 | Hyperglycemia impairs isoflurane-induced adenosine triphosphate-sensitive potassium channel activation in vascular smooth muscle cells. ( Kawano, T; Mawatari, K; Nakaya, Y; Oshita, S; Takahashi, A; Tanaka, K, 2008) |
| "Hyperglycemia generates reactive oxygen species and prevents isoflurane-induced preconditioning." | 7.72 | N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. ( Kehl, F; Kersten, JR; Krolikowski, JG; Pagel, PS; Warltier, DC; Weihrauch, D, 2003) |
| "Results indicated that pretreatments with medetomidine and alfaxalone or with medetomidine, midazolam, and alfaxalone were useful for preventing stress-related hormonal and metabolic responses, other than hyperglycemia, during isoflurane anesthesia and surgery in cats." | 5.51 | A randomized clinical trial on effects of alfaxalone combined with medetomidine and midazolam in preventing stress-related neurohormonal and metabolic responses of isoflurane-anesthetized cats undergoing surgery. ( Hikasa, Y; Kamohara, H; Kamohara, T, 2022) |
| "Isoflurane anesthesia is reported to induce insulin resistance (IR) in the peripheral tissues." | 3.96 | Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice. ( Fang, X; Gu, X; Ma, Z; Wu, H; Xia, T; Xu, F; Zhao, X, 2020) |
| "Early apoptosis was significantly higher in isoflurane and propofol anesthetized animals subjected to renal ischemia-reperfusion injury when compared to both cyclosporine A treated and sham groups." | 3.85 | Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats. ( Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT, 2017) |
| "Hyperglycemia can blunt the cardioprotective effects of isoflurane in the setting of ischemia-reperfusion injury." | 3.83 | High Glucose Attenuates Anesthetic Cardioprotection in Stem-Cell-Derived Cardiomyocytes: The Role of Reactive Oxygen Species and Mitochondrial Fission. ( Bai, X; Bosnjak, ZJ; Canfield, SG; Godshaw, B; Twaroski, D; Zaja, I, 2016) |
| "The aim of this study was to investigate blood glucose level of desflurane and sevoflurane on blood glucose in diabetic rats undergoing acute hyperglycemia." | 3.83 | Are there any effects of Sevoflurane and Desflurane anaesthesia on blood glucose levels in acute hyperglycemic diabetic rats? ( Arpaci, AH; Arslan, M; Beskardes, E; Dikmen, B; Gunes, I; Kalayci, D; Kurtipek, O, 2016) |
| " The anesthetic isoflurane induced marked insulin resistance, whereas lipid emulsion induced mild insulin resistance." | 3.80 | Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets. ( Engelhardt, JF; Hu, S; Liang, B; Nelson, DJ; Norris, AW; Ode, KL; Philipson, LH; Sui, H; Sun, X; Uc, A; Yao, J; Yi, Y, 2014) |
| "To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia." | 3.79 | Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia? ( Carraretto, AR; Carvalho, LR; Castiglia, YM; Deffune, E; Golim, Mde A; Souza, AV; Vianna Filho, PT; Vianna, PT, 2013) |
| "Because the potential neuroprotective effect of isoflurane is controversial, we attempted to study whether isoflurane after treatment provides neuroprotection in a rat model of hyperglycemia-induced ischemic hemorrhagic transformation." | 3.77 | Isoflurane enhanced hemorrhagic transformation by impairing antioxidant enzymes in hyperglycemic rats with middle cerebral artery occlusion. ( He, Z; Hu, Q; Ma, Q; Tang, J; Zhan, Y; Zhang, J; Zhou, C, 2011) |
| "Myocardial infarct size was measured in rabbits in the absence or presence of APC (30 min of isoflurane), with or without hyperglycemia, and in the presence or absence of the BH4 precursor sepiapterin." | 3.76 | Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms. ( Amour, J; Brzezinska, AK; Du, J; Jager, Z; Kersten, JR; Pratt, PF; Shi, Y; Sullivan, C; Vladic, N; Warltier, DC; Weihrauch, D, 2010) |
| "Our results suggest that the metabolic stress of hyperglycemia can impair isoflurane-induced vascular K(ATP) channel activity mediated by excessive activation of PKC." | 3.74 | Hyperglycemia impairs isoflurane-induced adenosine triphosphate-sensitive potassium channel activation in vascular smooth muscle cells. ( Kawano, T; Mawatari, K; Nakaya, Y; Oshita, S; Takahashi, A; Tanaka, K, 2008) |
| "Hyperglycemia generates reactive oxygen species and prevents isoflurane-induced preconditioning." | 3.72 | N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. ( Kehl, F; Kersten, JR; Krolikowski, JG; Pagel, PS; Warltier, DC; Weihrauch, D, 2003) |
| "Desflurane has demonstrated the indistinguishable blood glucose level and hemodynamic response from isoflurane anesthesia intraoperatively in neurosurgical patients, confirming a comparable pattern of blood glucose concentration intensifying over time spends." | 2.74 | Blood glucose level in neurosurgery. Is it different between isoflurane and desflurane anesthesia? ( Akavipat, P; Pannak, S; Polsayom, N; Punkla, W, 2009) |
| "Hyperglycemia is known to inhibit myocardial anesthetic postconditioning." | 1.42 | Activation of Adenosine Triphosphate-regulated Potassium Channels during Reperfusion Restores Isoflurane Postconditioning-induced Cardiac Protection in Acutely Hyperglycemic Rabbits. ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2015) |
| "Hyperglycemia is known to inhibit ischemic and anesthetic preconditioning." | 1.36 | Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling. ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2010) |
| "The presence of cerebral hemorrhage after reperfusion was checked macroscopically and infarct volume with 2,3,5-triphenyltetrazolium staining." | 1.30 | Hyperglycemia and the vascular effects of cerebral ischemia. ( Betz, AL; Kawai, N; Keep, RF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 13 (56.52) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Kamohara, H | 1 |
| Kamohara, T | 1 |
| Hikasa, Y | 1 |
| Fang, X | 1 |
| Xia, T | 1 |
| Xu, F | 1 |
| Wu, H | 1 |
| Ma, Z | 1 |
| Zhao, X | 1 |
| Gu, X | 1 |
| Tokunaga, R | 1 |
| Paquette, T | 1 |
| Tsurugizawa, T | 1 |
| Leblond, H | 1 |
| Piché, M | 1 |
| Lemos, SV | 1 |
| Vianna, IG | 1 |
| Castiglia, YM | 2 |
| Golim, MA | 1 |
| Souza, AV | 2 |
| Carvalho, LR | 2 |
| Deffune, E | 2 |
| Nascimento, PD | 1 |
| Módolo, NS | 1 |
| Vianna, PT | 2 |
| Carraretto, AR | 1 |
| Vianna Filho, PT | 1 |
| Golim, Mde A | 1 |
| Baotic, I | 1 |
| Ge, ZD | 1 |
| Sedlic, F | 2 |
| Coon, A | 1 |
| Weihrauch, D | 3 |
| Warltier, DC | 3 |
| Kersten, JR | 3 |
| Sui, H | 1 |
| Yi, Y | 1 |
| Yao, J | 1 |
| Liang, B | 1 |
| Sun, X | 1 |
| Hu, S | 1 |
| Uc, A | 1 |
| Nelson, DJ | 1 |
| Ode, KL | 1 |
| Philipson, LH | 1 |
| Engelhardt, JF | 1 |
| Norris, AW | 1 |
| Zhao, L | 1 |
| Nowak, TS | 1 |
| Raphael, J | 2 |
| Gozal, Y | 2 |
| Navot, N | 2 |
| Zuo, Z | 2 |
| Canfield, SG | 2 |
| Zaja, I | 1 |
| Godshaw, B | 1 |
| Twaroski, D | 1 |
| Bai, X | 2 |
| Bosnjak, ZJ | 2 |
| Dikmen, B | 1 |
| Arpaci, AH | 1 |
| Kalayci, D | 1 |
| Gunes, I | 1 |
| Beskardes, E | 1 |
| Kurtipek, O | 1 |
| Arslan, M | 1 |
| Cata, JP | 1 |
| Hagan, KB | 1 |
| Bhavsar, SD | 1 |
| Arunkumar, R | 1 |
| Grasu, R | 1 |
| Dang, A | 1 |
| Carlson, R | 1 |
| Arnold, B | 1 |
| Potylchansky, Y | 1 |
| Lipski, I | 1 |
| McHugh, T | 1 |
| Jimenez, F | 1 |
| Nguyen, AT | 1 |
| Feng, L | 1 |
| Rahlfs, TF | 1 |
| Weber, NC | 1 |
| Goletz, C | 1 |
| Huhn, R | 1 |
| Grueber, Y | 1 |
| Preckel, B | 1 |
| Schlack, W | 1 |
| Ebel, D | 1 |
| Akavipat, P | 1 |
| Polsayom, N | 1 |
| Pannak, S | 1 |
| Punkla, W | 1 |
| Amour, J | 1 |
| Brzezinska, AK | 1 |
| Jager, Z | 1 |
| Sullivan, C | 1 |
| Du, J | 1 |
| Vladic, N | 1 |
| Shi, Y | 1 |
| Pratt, PF | 1 |
| Hu, Q | 1 |
| Ma, Q | 1 |
| Zhan, Y | 1 |
| He, Z | 1 |
| Tang, J | 1 |
| Zhou, C | 1 |
| Zhang, J | 1 |
| Sepac, A | 1 |
| Muravyeva, MY | 1 |
| Kehl, F | 1 |
| Krolikowski, JG | 1 |
| Pagel, PS | 1 |
| Lu, CC | 1 |
| Ho, ST | 1 |
| Wang, JJ | 1 |
| Wong, CS | 1 |
| Tsai, CS | 1 |
| Chang, SY | 1 |
| Lin, CY | 1 |
| Kawano, T | 1 |
| Tanaka, K | 1 |
| Mawatari, K | 1 |
| Oshita, S | 1 |
| Takahashi, A | 1 |
| Nakaya, Y | 1 |
| Kawai, N | 1 |
| Keep, RF | 1 |
| Betz, AL | 1 |
| Lattermann, R | 1 |
| Schricker, T | 1 |
| Wachter, U | 1 |
| Georgieff, M | 1 |
| Goertz, A | 1 |
4 trials available for isoflurane and Hyperglycemia
| Article | Year |
|---|---|
A randomized clinical trial on effects of alfaxalone combined with medetomidine and midazolam in preventing stress-related neurohormonal and metabolic responses of isoflurane-anesthetized cats undergoing surgery.
Topics: Anesthetics, Combined; Animals; Cat Diseases; Cats; Hyperglycemia; Isoflurane; Medetomidine; Midazol | 2022 |
Blood glucose level in neurosurgery. Is it different between isoflurane and desflurane anesthesia?
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Glucose; Desflurane; | 2009 |
Minimal low-flow isoflurane-based anesthesia benefits patients undergoing coronary revascularization via preventing hyperglycemia and maintaining metabolic homeostasis.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2003 |
Understanding the mechanisms by which isoflurane modifies the hyperglycemic response to surgery.
Topics: Aged; Analgesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Catecholamines; Double-B | 2001 |
19 other studies available for isoflurane and Hyperglycemia
| Article | Year |
|---|---|
Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice.
Topics: Anesthetics, Inhalation; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, | 2020 |
Fasting prevents medetomidine-induced hyperglycaemia and alterations of neurovascular coupling in the somatosensory cortex of the rat during noxious stimulation.
Topics: Animals; Fasting; Hyperglycemia; Isoflurane; Male; Medetomidine; Neurovascular Coupling; Rats; Somat | 2021 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; | 2017 |
Do propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
Topics: Acute Disease; Anesthesia; Anesthetics; Animals; Cell Survival; Creatinine; Flow Cytometry; Hypergly | 2013 |
Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia.
Topics: Acute Disease; Animals; Apolipoprotein A-I; Blood Glucose; Caveolin 1; Cells, Cultured; Coronary Ves | 2013 |
Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets.
Topics: Analysis of Variance; Animals; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Ferrets; Glucos | 2014 |
Preconditioning cortical lesions reduce the incidence of peri-infarct depolarizations during focal ischemia in the Spontaneously Hypertensive Rat: interaction with prior anesthesia and the impact of hyperglycemia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebellar Cortex; Cerebral | 2015 |
Activation of Adenosine Triphosphate-regulated Potassium Channels during Reperfusion Restores Isoflurane Postconditioning-induced Cardiac Protection in Acutely Hyperglycemic Rabbits.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Blood Glucose; Creatine Kinase, MB Form; Heart Diseases | 2015 |
High Glucose Attenuates Anesthetic Cardioprotection in Stem-Cell-Derived Cardiomyocytes: The Role of Reactive Oxygen Species and Mitochondrial Fission.
Topics: Anesthetics, Inhalation; Antioxidants; Biomarkers; Cell Differentiation; Cell Survival; Cells, Cultu | 2016 |
Are there any effects of Sevoflurane and Desflurane anaesthesia on blood glucose levels in acute hyperglycemic diabetic rats?
Topics: Anesthetics, Inhalation; Animals; Blood Glucose; Desflurane; Diabetes Mellitus, Experimental; Humans | 2016 |
The use of isoflurane and desflurane as inhalational agents for glioblastoma surgery. A survival analysis.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemoradiotherapy; Combined Modality T | 2017 |
Blockade of anaesthetic-induced preconditioning in the hyperglycaemic myocardium: the regulation of different mitogen-activated protein kinases.
Topics: Anesthetics; Anesthetics, Inhalation; Animals; Blood Glucose; Blood Pressure; Blotting, Western; Des | 2008 |
Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms.
Topics: Anesthetics; Animals; Biopterins; Blotting, Western; Chromatography, High Pressure Liquid; Coronary | 2010 |
Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling.
Topics: Anesthetics; Animals; Blood Glucose; Blood Pressure; Creatine Kinase, MB Form; Glucose; Heart; Heart | 2010 |
Isoflurane enhanced hemorrhagic transformation by impairing antioxidant enzymes in hyperglycemic rats with middle cerebral artery occlusion.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Brain Ischemia; Catalase; Cerebral Hemorrhage; Hyper | 2011 |
Marked hyperglycemia attenuates anesthetic preconditioning in human-induced pluripotent stem cell-derived cardiomyocytes.
Topics: Anesthetics; Anesthetics, Inhalation; Cardiac Myosins; Cell Differentiation; Diabetes Mellitus, Type | 2012 |
N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Collateral Circulation; Coronary Circulation; Dogs | 2003 |
Hyperglycemia impairs isoflurane-induced adenosine triphosphate-sensitive potassium channel activation in vascular smooth muscle cells.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Enzyme Activators; Free Radical Scavengers; Gluco | 2008 |
Hyperglycemia and the vascular effects of cerebral ischemia.
Topics: Anesthetics; Animals; Blood Glucose; Body Temperature; Cerebral Arteries; Cerebral Hemorrhage; Cereb | 1997 |