dehydroepiandrosterone has been researched along with Hyperglycemia in 17 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin might be a safe and useful supplement to ameliorate PCOS-associated hyperandrogenemia and hyperglycemia." | 9.41 | Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trial. ( Heshmati, J; Moini, A; Mojtahedi, MF; Morvaridzadeh, M; Palmowski, A; Salehi, M; Sepidarkish, M; Shidfar, F, 2021) |
| "Acute dehydroepiandrosterone (DHEA) administration improves hyperglycemia in rats with streptozotocin (STZ)-induced type 1 diabetes mellitus." | 7.80 | Acute administration of diosgenin or dioscorea improves hyperglycemia with increases muscular steroidogenesis in STZ-induced type 1 diabetic rats. ( Fujita, S; Iemitsu, M; Sato, K, 2014) |
| "This study was undertaken to assess the effects of dehydroepiandrosterone (DHEA) administration and exercise training on muscular DHEA and 5α-dihydrotestosterone (DHT) levels and hyperglycemia in diet-induced obese and hyperglycemic rats." | 7.77 | Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats. ( Aizawa, K; Fujita, S; Iemitsu, M; Mesaki, N; Sato, K, 2011) |
| "Curcumin might be a safe and useful supplement to ameliorate PCOS-associated hyperandrogenemia and hyperglycemia." | 5.41 | Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trial. ( Heshmati, J; Moini, A; Mojtahedi, MF; Morvaridzadeh, M; Palmowski, A; Salehi, M; Sepidarkish, M; Shidfar, F, 2021) |
| "Dehydroepiandrosterone, which has recently been found to have antioxidant properties, was administered i." | 5.30 | Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats. ( Aragno, M; Boccuzzi, G; Brignardello, E; Danni, O; Gatto, V; Tamagno, E, 1997) |
| "Acute dehydroepiandrosterone (DHEA) administration improves hyperglycemia in rats with streptozotocin (STZ)-induced type 1 diabetes mellitus." | 3.80 | Acute administration of diosgenin or dioscorea improves hyperglycemia with increases muscular steroidogenesis in STZ-induced type 1 diabetic rats. ( Fujita, S; Iemitsu, M; Sato, K, 2014) |
| "This study was undertaken to assess the effects of dehydroepiandrosterone (DHEA) administration and exercise training on muscular DHEA and 5α-dihydrotestosterone (DHT) levels and hyperglycemia in diet-induced obese and hyperglycemic rats." | 3.77 | Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats. ( Aizawa, K; Fujita, S; Iemitsu, M; Mesaki, N; Sato, K, 2011) |
| " Since chronic hyperglycemia is central to diabetic complications, and poorly differentiated cells are oxidatively more vulnerable, we currently investigated the effect of glycemic status on MG-induced apoptosis in naïve (nPC12) cells focusing on glutathione-to-glutathione disulfide (GSH/GSSG) redox signaling." | 3.73 | Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression. ( Aw, TY; Okayama, N; Okouchi, M, 2005) |
| "Dehydroepiandrosterone (DHEA) has been reported to possess antioxidant properties." | 1.31 | Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment. ( Aragno, M; Boccuzzi, G; Brignardello, E; Danni, O; Manti, R; Parola, S; Tamagno, E, 2000) |
| "Dehydroepiandrosterone, which has recently been found to have antioxidant properties, was administered i." | 1.30 | Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats. ( Aragno, M; Boccuzzi, G; Brignardello, E; Danni, O; Gatto, V; Tamagno, E, 1997) |
| "Dehydroepiandrosterone-treatment (4 mg/day for 3 weeks) protected tissues against lipid peroxidation: liver, kidney and brain homogenates from dehydroepiandrosterone-treated animals showed a significant decrease of both thiobarbituric acid reactive substances and fluorescent chromolipids formation." | 1.30 | Dehydroepiandrosterone protects tissues of streptozotocin-treated rats against oxidative stress. ( Aragno, M; Boccuzzi, G; Brignardello, E; Danni, O; Gatto, V; Parola, S; Tamagno, E, 1999) |
| "Dehydroepiandrosterone (DHEA) was fed at 0." | 1.27 | Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. ( Coleman, DL; Leiter, EH; Schwizer, RW, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Heshmati, J | 1 |
| Moini, A | 1 |
| Sepidarkish, M | 1 |
| Morvaridzadeh, M | 1 |
| Salehi, M | 1 |
| Palmowski, A | 1 |
| Mojtahedi, MF | 1 |
| Shidfar, F | 1 |
| Sato, K | 3 |
| Fujita, S | 2 |
| Iemitsu, M | 3 |
| Aizawa, K | 2 |
| Ajisaka, R | 1 |
| Wang, T | 1 |
| Villegas, S | 1 |
| Huang, Y | 1 |
| White, SK | 1 |
| Ahlem, C | 1 |
| Lu, M | 1 |
| Olefsky, JM | 1 |
| Reading, C | 1 |
| Frincke, JM | 1 |
| Alleva, D | 1 |
| Flores-Riveros, J | 1 |
| Mesaki, N | 1 |
| González, F | 2 |
| Nair, KS | 2 |
| Daniels, JK | 2 |
| Basal, E | 2 |
| Schimke, JM | 2 |
| Blair, HE | 1 |
| Okouchi, M | 1 |
| Okayama, N | 1 |
| Aw, TY | 1 |
| Boudou, P | 1 |
| Sobngwi, E | 1 |
| Ibrahim, F | 1 |
| Porcher, R | 1 |
| Vexiau, P | 1 |
| Calvo, F | 1 |
| Gautier, JF | 1 |
| Bassotti, G | 1 |
| Di Sarra, D | 1 |
| Pietrobono, D | 1 |
| Schiaffini, R | 1 |
| Battocletti, T | 1 |
| D'Amico, T | 1 |
| Gargiulo, P | 1 |
| Coleman, DL | 2 |
| Schwizer, RW | 1 |
| Leiter, EH | 1 |
| Yamauchi, A | 1 |
| Takei, I | 1 |
| Nakamoto, S | 1 |
| Ohashi, N | 1 |
| Kitamura, Y | 1 |
| Tokui, M | 1 |
| Nakano, S | 1 |
| Takayama, S | 1 |
| Kasuga, A | 1 |
| Katsukawa, F | 1 |
| Saruta, T | 1 |
| Aragno, M | 4 |
| Brignardello, E | 4 |
| Tamagno, E | 4 |
| Gatto, V | 2 |
| Danni, O | 4 |
| Boccuzzi, G | 4 |
| Parola, S | 3 |
| Manti, R | 2 |
| Betteto, S | 1 |
3 trials available for dehydroepiandrosterone and Hyperglycemia
| Article | Year |
|---|---|
Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Androgens; Blood Glucose; Curcumin; Dehydroepiandrosterone; Dietary Supplements; | 2021 |
Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation in lean reproductive-age women.
Topics: Adult; Body Mass Index; Cell Nucleus; Cytokines; Dehydroepiandrosterone; Double-Blind Method; Female | 2012 |
Hyperandrogenism sensitizes leukocytes to hyperglycemia to promote oxidative stress in lean reproductive-age women.
Topics: Adult; Blood Glucose; Body Composition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Doub | 2012 |
14 other studies available for dehydroepiandrosterone and Hyperglycemia
| Article | Year |
|---|---|
Acute administration of diosgenin or dioscorea improves hyperglycemia with increases muscular steroidogenesis in STZ-induced type 1 diabetic rats.
Topics: Animals; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2014 |
DHEA improves impaired activation of Akt and PKC zeta/lambda-GLUT4 pathway in skeletal muscle and improves hyperglycaemia in streptozotocin-induced diabetes rats.
Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus, Experimen | 2009 |
Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dehydroepiandrosterone; Gene Expression Profiling; Glu | 2010 |
Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats.
Topics: Animals; Blood Glucose; Body Weight; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dietary | 2011 |
Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression.
Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Brain; Cell Respiration; Dehydroepiandro | 2005 |
Hyperglycaemia acutely decreases circulating dehydroepiandrosterone levels in healthy men.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Analysis of Variance; Androgens; Blood Glucose; Body Compositio | 2006 |
Polyglandular autoimmune endocrine insufficiency complicated by severe osteoporosis.
Topics: Addison Disease; Adult; Asthenia; Bone Density; Dehydroepiandrosterone; Female; Gonadal Steroid Horm | 2006 |
Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice.
Topics: Aging; Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Female; Gluco | 1984 |
Hyperglycemia decreases dehydroepiandrosterone in Japanese male with impaired glucose tolerance and low insulin response.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Humans; Hype | 1996 |
Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Brain; Dehydroepiandrosterone; Glucose; Hyperglycemia; | 1997 |
Dehydroepiandrosterone protects tissues of streptozotocin-treated rats against oxidative stress.
Topics: Animals; Antioxidants; Brain; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; Drug Evaluati | 1999 |
Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment.
Topics: Animals; Antioxidants; Axons; Cell Membrane; Dehydroepiandrosterone; Diabetes Mellitus, Experimental | 2000 |
Oxidative stress and eicosanoids in the kidneys of hyperglycemic rats treated with dehydroepiandrosterone.
Topics: Animals; Antioxidants; Arachidonic Acids; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; D | 2001 |
Therapeutic effects of dehydroepiandrosterone (DHEA) and its metabolites in obese-hyperglycemic mutant mice.
Topics: Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Hyperglycemia; Insulin; Mice; Mice, Inb | 1988 |