hexamethonium has been researched along with Hyperglycemia in 10 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracranial injection of D-mannitol (MA) or D-glucose (GL) caused photoperiodic hyperglycemia in rats; MA injection elicited hyperglycemia only in the light period, while GL injection induced it only in the dark period." | 7.67 | Role of autonomic nervous system in the time-dependent hyperglycemia induced by intracranial injection of D-mannitol and D-glucose. ( Nagai, K; Nakagawa, H; Yamamoto, H, 1984) |
| "Intracranial injection of D-mannitol (MA) or D-glucose (GL) caused photoperiodic hyperglycemia in rats; MA injection elicited hyperglycemia only in the light period, while GL injection induced it only in the dark period." | 3.67 | Role of autonomic nervous system in the time-dependent hyperglycemia induced by intracranial injection of D-mannitol and D-glucose. ( Nagai, K; Nakagawa, H; Yamamoto, H, 1984) |
| "Previously we found that in rats, electrical stimulation of the suprachiasmatic nucleus (SCN) of the hypothalamus elicited hyperglycemia associated with hyperglucagonemia without immediate hyperinsulinemia." | 3.67 | Involvement of adrenergic mechanism in hyperglycemia due to SCN stimulation. ( Fujii, T; Inoue, S; Nagai, K; Nakagawa, H, 1989) |
| "Electrical stimulation of the lateral part of the dorsal parabrachial nucleus (PBD) induces hyperglycemia by enhancing glucagon secretion and suppressing insulin secretion in rats." | 3.67 | Hyperglycemia induced by electrical stimulation of lateral part of dorsal parabrachial nucleus. ( Fujiwara, T; Nagai, K; Nakagawa, H; Takagi, S, 1988) |
| "To determine the mechanism of time-dependent hyperglycemia due to intracranial injection of 2-deoxy-D-glucose (2DG), we examined the effects of various blockers of the autonomic nervous system on the hyperglycemia and hyperglucagonemia induced by intracranial injection of 2DG in male Wistar rats in light and dark periods." | 3.67 | Time-dependent involvement of autonomic nervous system in hyperglycemia due to 2-deoxy-D-glucose. ( Nagai, K; Nakagawa, H; Yamamoto, H, 1988) |
| "Pretreatment with hexamethonium, as well as truncal vagotomy, abolished the gastric motor responses to hyperglycemia (250 mg/dl), and perivagal and gastroduodenal applications of capsaicin significantly reduced the gastric responses to hyperglycemia." | 1.35 | Gastric relaxation induced by hyperglycemia is mediated by vagal afferent pathways in the rat. ( Lu, YX; Owyang, C; Zhou, SY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Savoy, YE | 1 |
| Ashton, MA | 1 |
| Miller, MW | 1 |
| Nedza, FM | 1 |
| Spracklin, DK | 1 |
| Hawthorn, MH | 1 |
| Rollema, H | 1 |
| Matos, FF | 1 |
| Hajos-Korcsok, E | 1 |
| Zhou, SY | 1 |
| Lu, YX | 1 |
| Owyang, C | 1 |
| Yamamoto, H | 2 |
| Nagai, K | 4 |
| Nakagawa, H | 4 |
| Sugimoto, Y | 1 |
| Yamada, J | 1 |
| Yoshikawa, T | 1 |
| Horisaka, K | 1 |
| das Neves, J | 1 |
| Hackl, LP | 1 |
| Freitas, CG | 1 |
| Paschoalini, MA | 1 |
| Marino-Neto, J | 1 |
| Fujii, T | 1 |
| Inoue, S | 1 |
| Marubashi, S | 1 |
| Tominaga, M | 1 |
| Katagiri, T | 1 |
| Yamatani, K | 1 |
| Yawata, Y | 1 |
| Hara, M | 1 |
| Sasaki, H | 1 |
| Iguchi, A | 1 |
| Gotoh, M | 1 |
| Matsunaga, H | 1 |
| Ohuchi, M | 1 |
| Nomura, T | 1 |
| Sakamoto, N | 1 |
| Fujiwara, T | 1 |
| Takagi, S | 1 |
10 other studies available for hexamethonium and Hyperglycemia
| Article | Year |
|---|---|
Differential effects of various typical and atypical antipsychotics on plasma glucose and insulin levels in the mouse: evidence for the involvement of sympathetic regulation.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Blood Glucose; Dose-Response Relationsh | 2010 |
Gastric relaxation induced by hyperglycemia is mediated by vagal afferent pathways in the rat.
Topics: Afferent Pathways; Animals; Blood Glucose; Capsaicin; Carbachol; Electric Stimulation; Fenclonine; G | 2008 |
Role of autonomic nervous system in the time-dependent hyperglycemia induced by intracranial injection of D-mannitol and D-glucose.
Topics: Animals; Atropine; Autonomic Nervous System; Circadian Rhythm; Darkness; Glucose; Hexamethonium; Hex | 1984 |
Effects of the 5-HT2C/2B receptor agonist 1-(3-chlorophenyl) piperazine on plasma glucose levels of rats.
Topics: Amphetamines; Animals; Blood Glucose; Hexamethonium; Hyperglycemia; Male; Piperazines; Rats; Rats, S | 1996 |
Central injections of noradrenaline and adrenaline differentially affect plasma free fatty acid and glucose in conscious pigeons (Columba livia).
Topics: Animals; Autonomic Nervous System; Blood Glucose; Columbidae; Consciousness; Energy Metabolism; Epin | 2000 |
Involvement of adrenergic mechanism in hyperglycemia due to SCN stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System; Electric Stimulation; Female; Gluca | 1989 |
Hyperglycaemic effect of glucagon administered intracerebroventricularly in the rat.
Topics: Adrenalectomy; Animals; Atropine; Autonomic Nervous System; Blood Glucose; Glucagon; Hexamethonium; | 1985 |
Increase in plasma glucose concentration after intracerebroventricular injection of N,O'-dibutyryl cyclic adenosine 3',5'-monophosphate.
Topics: Adenosine Triphosphate; Animals; Atropine; Blood Glucose; Bucladesine; Cyclic AMP; Dibutyryl Cyclic | 1986 |
Hyperglycemia induced by electrical stimulation of lateral part of dorsal parabrachial nucleus.
Topics: Animals; Atropine; Blood Glucose; Electric Stimulation; Female; Glucagon; Hexamethonium; Hexamethoni | 1988 |
Time-dependent involvement of autonomic nervous system in hyperglycemia due to 2-deoxy-D-glucose.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Glucose; Circadian Rhythm; Deoxyglucose; Glucagon | 1988 |