pyrilamine has been researched along with Hyperglycemia in 4 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The injection of pyrilamine (5 x 10(-7) mol) into the third cerebral ventricle suppressed the hyperglycemia induced by intraventricular injection of histamine (5 x 10(-7) mol)." | 7.68 | Histamine-induced, central nervous system-mediated hyperglycemia is suppressed by atropine in the brain. ( Hiyoshi, Y; Iguchi, A; Li, X; Nonogaki, K; Ozawa, K; Sakamoto, N; Tamagawa, T; Watanabe, G, 1993) |
| " To determine whether brain histamine receptors are involved in cholinergic system transmission with regard to central nervous system (CNS)-mediated glucoregulation, we examined the effects of the H1 receptor antagonist pyrilamine and the H2 receptor antagonist ranitidine on neostigmine-induced hyperglycemia in anesthetized rats." | 7.68 | Role of brain histamine H1- and H2-receptors in neostigmine-induced hyperglycemia in rats. ( Hiyoshi, Y; Iguchi, A; Li, X; Nonogaki, K; Sakamoto, N; Tamagawa, T; Watanabe, G, 1992) |
| " The injection of pyrilamine (5 x 10(-7) mol) into the third cerebral ventricle suppressed the hyperglycemia induced by intraventricular injection of histamine (5 x 10(-7) mol)." | 3.68 | Histamine-induced, central nervous system-mediated hyperglycemia is suppressed by atropine in the brain. ( Hiyoshi, Y; Iguchi, A; Li, X; Nonogaki, K; Ozawa, K; Sakamoto, N; Tamagawa, T; Watanabe, G, 1993) |
| "We studied the effects of the histamine H1 receptor antagonists diphenhydramine and pyrilamine, the H2 receptor antagonist ranitidine and the muscarinic receptor antagonist atropine injected into the third cerebral ventricle on prostaglandin F2 alpha (PGF2 alpha)-induced hyperglycemia in anesthetized fed rats." | 3.68 | Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats. ( Iguchi, A; Kunoh, Y; Nonogaki, K; Sakamoto, N; Tamagawa, T; Zhu, LX, 1993) |
| " To determine whether brain histamine receptors are involved in cholinergic system transmission with regard to central nervous system (CNS)-mediated glucoregulation, we examined the effects of the H1 receptor antagonist pyrilamine and the H2 receptor antagonist ranitidine on neostigmine-induced hyperglycemia in anesthetized rats." | 3.68 | Role of brain histamine H1- and H2-receptors in neostigmine-induced hyperglycemia in rats. ( Hiyoshi, Y; Iguchi, A; Li, X; Nonogaki, K; Sakamoto, N; Tamagawa, T; Watanabe, G, 1992) |
| "5-2 mg/kg), chlorpheniramine (1-4 mg/kg) and promethazine (1-4 mg/kg), inhibited dose-dependently the HA-induced hyperglycemia, whereas an H2-receptor antagonist, cimetidine (80 nmol i." | 3.67 | Mechanism of the central hyperglycemic action of histamine in mice. ( Itoh, Y; Nishibori, M; Oishi, R; Saeki, K, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nonogaki, K | 3 |
| Li, X | 2 |
| Tamagawa, T | 3 |
| Watanabe, G | 2 |
| Hiyoshi, Y | 2 |
| Ozawa, K | 1 |
| Sakamoto, N | 3 |
| Iguchi, A | 3 |
| Zhu, LX | 1 |
| Kunoh, Y | 1 |
| Nishibori, M | 1 |
| Itoh, Y | 1 |
| Oishi, R | 1 |
| Saeki, K | 1 |
4 other studies available for pyrilamine and Hyperglycemia
| Article | Year |
|---|---|
Histamine-induced, central nervous system-mediated hyperglycemia is suppressed by atropine in the brain.
Topics: Animals; Atropine; Brain; Central Nervous System; Dose-Response Relationship, Drug; Histamine; Hista | 1993 |
Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats.
Topics: Animals; Atropine; Dinoprost; Diphenhydramine; Histamine H1 Antagonists; Hyperglycemia; Injections, | 1993 |
Role of brain histamine H1- and H2-receptors in neostigmine-induced hyperglycemia in rats.
Topics: Animals; Blood Glucose; Brain; Hyperglycemia; Male; Neostigmine; Pyrilamine; Ranitidine; Rats; Rats, | 1992 |
Mechanism of the central hyperglycemic action of histamine in mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpheniramine; Chromatography, High Pressure Liquid; Corti | 1987 |