1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Hyperglycemia in 3 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the effects could be mediated by mitochondrial ATP-sensitive potassium (m-KATP) channels." | 7.78 | High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels. ( Cho, S; Higashijima, U; Ichinomiya, T; Maekawa, T; Matsumoto, S; Sumikawa, K, 2012) |
| "The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the effects could be mediated by mitochondrial ATP-sensitive potassium (m-KATP) channels." | 3.78 | High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels. ( Cho, S; Higashijima, U; Ichinomiya, T; Maekawa, T; Matsumoto, S; Sumikawa, K, 2012) |
| "Since inositol (Ins) depletion appears to be an important mechanism of cell injury in diabetic glomerulopathy, we studied Ins transport in cultured rat mesangial cells during hyperglycemia." | 3.68 | Regulation of inositol transport by glucose and protein kinase C in mesangial cells. ( Crews, FT; Guzman, NJ, 1992) |
| "In fasudil-treated rats, the internal carotid artery narrowing was ameliorated and L-NAME-induced regional constriction was abolished." | 1.43 | Vessel Dilation Attenuates Endothelial Dysfunction Following Middle Cerebral Artery Occlusion in Hyperglycemic Rats. ( Jiang, Z; Lin, XJ; Mu, ZH; Wang, LP; Wang, YT; Xi, Y; Yang, GY; Zhang, ZJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mu, ZH | 1 |
| Jiang, Z | 1 |
| Lin, XJ | 1 |
| Wang, LP | 1 |
| Xi, Y | 1 |
| Zhang, ZJ | 1 |
| Wang, YT | 1 |
| Yang, GY | 1 |
| Ichinomiya, T | 1 |
| Cho, S | 1 |
| Higashijima, U | 1 |
| Matsumoto, S | 1 |
| Maekawa, T | 1 |
| Sumikawa, K | 1 |
| Guzman, NJ | 1 |
| Crews, FT | 1 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hyperglycemia
| Article | Year |
|---|---|
Vessel Dilation Attenuates Endothelial Dysfunction Following Middle Cerebral Artery Occlusion in Hyperglycemic Rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Cerebral Angiography; Cerebral Arteri | 2016 |
High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Glucose; Decanoic Acids; Diazoxide; Do | 2012 |
Regulation of inositol transport by glucose and protein kinase C in mesangial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Transport, Active; Cel | 1992 |