quinacrine has been researched along with Epilepsy in 18 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| UZUNOV, G | 1 |
| BOZHINOV, S | 1 |
| GEORGIEV, I | 1 |
| NOBILE, M | 2 |
| MILLER, RA | 1 |
| VAZQUEZ, HJ | 1 |
| HOJMAN, N | 1 |
| QUIROGA, FE | 1 |
| LIEVENS, P | 1 |
| AYALA HURTADO, F | 1 |
| SOREL, L | 2 |
| EVANS, PR | 1 |
| SIBLEY, WA | 1 |
| TUCKER, HJ | 1 |
| RANDT, CT | 1 |
| SCHOLL, ML | 1 |
| SULLI, G | 1 |
| VARRONE, F | 1 |
| GASTAUT, H | 1 |
| SIMON, H | 1 |
| Bower, BD | 1 |
| Jeavons, PM | 1 |
| Borda, I | 1 |
| Krant, M | 1 |
| Hohenauer, I | 1 |
| Schmoigl, S | 1 |
| Schwartz, JF | 1 |
1 review available for quinacrine and Epilepsy
| Article | Year |
|---|---|
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy; | 1963 |
17 other studies available for quinacrine and Epilepsy
| Article | Year |
|---|---|
[Experimental investigations on pathogenesis of atabrine epileptiform seizure].
Topics: Epilepsy; Glomerulonephritis; Quinacrine; Seizures | 1954 |
[Effects of atebrin on disposition toward experimental reflex epilepsy in guinea pigs].
Topics: Animals; Epilepsy; Epilepsy, Reflex; Guinea Pigs; Quinacrine | 1956 |
[Effects of atebrin on disposition toward experimental reflex epilepsy in guinea pigs].
Topics: Animals; Epilepsy; Epilepsy, Reflex; Guinea Pigs; Quinacrine | 1956 |
[Effects of atebrin on disposition toward experimental reflex epilepsy in guinea pigs].
Topics: Animals; Epilepsy; Epilepsy, Reflex; Guinea Pigs; Quinacrine | 1956 |
[Effects of atebrin on disposition toward experimental reflex epilepsy in guinea pigs].
Topics: Animals; Epilepsy; Epilepsy, Reflex; Guinea Pigs; Quinacrine | 1956 |
Mepacrine therapy for children with petit mal.
Topics: Child; Epilepsy; Humans; Infant; Primidone; Quinacrine | 1958 |
[Observations on quinacrine & chloroquine in the treatment of petit mal; preliminary report].
Topics: Chloroquine; Epilepsy; Epilepsy, Absence; Quinacrine | 1959 |
[Experimental study of the anti-epileptic action of mepacrine].
Topics: Anticonvulsants; Epilepsy; Quinacrine | 1959 |
[Atabrine and pyknolepsy].
Topics: Epilepsy; Epilepsy, Absence; Quinacrine | 1959 |
[Experimental and clinical anti-epileptic actions of mepacrine (atebrine), of celontin and of elyptene].
Topics: Anticonvulsants; Epilepsy; Quinacrine; Seizures; Succinimides | 1959 |
Mepacrine in the treatment of petit mal.
Topics: Epilepsy; Epilepsy, Absence; Quinacrine | 1962 |
Quinacrine in the treatment of refractory petit-mal epilepsy.
Topics: Epilepsy; Epilepsy, Absence; Quinacrine | 1962 |
CURRENT CONCEPTS IN THERAPY: TREATMENT OF SEIZURE DISORDERS (EPILEPSY). (CONCLUDED FROM DECEMBER 12).
Topics: Acetazolamide; Anticonvulsants; Child; Chlordiazepoxide; Dextroamphetamine; Epilepsy; Epilepsy, Abse | 1963 |
[CLASSIFICATION OF EPILEPSY AND ITS TREATMENT].
Topics: Acetazolamide; Anticonvulsants; Barbiturates; Classification; Epilepsy; Humans; Hydantoins; Neurosur | 1963 |
CERTAIN BASIC CONCEPTS CONCERNING THE TREATMENT OF THE EPILEPSIES.
Topics: Amphetamine; Anticonvulsants; Barbiturates; Child; Drug Therapy; Electroencephalography; Epilepsy; E | 1964 |
Epileptic fit after oral administration of atabrine (in Hebrew; English summary).
Topics: Administration, Oral; Epilepsy; Language; Malaria; Quinacrine; Seizures | 1950 |
The "happy puppet" syndrome.
Topics: Child; Chlordiazepoxide; Electroencephalography; Epilepsy; Ethosuximide; Eye Diseases; Facial Expres | 1967 |
Convulsions following intrapleural administration of quinacrine hydrochloride.
Topics: Adult; Breast Neoplasms; Epilepsy; Female; Genital Neoplasms, Female; Humans; Middle Aged; Neoplasm | 1967 |
[Experience with a combination of ethosuximide and mepacrine (Acrisuxin) in the treatment of chronic epileptic seizures in children].
Topics: Child; Child, Preschool; Chronic Disease; Drug Combinations; Epilepsy; Epilepsy, Absence; Epilepsy, | 1972 |
Recent advances in treating epileptic children.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Epilepsy; Ethosuximide; Humans; Quinacrine | 1968 |