disulfiram has been researched along with Epilepsy in 12 studies
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of a 35-year-old man presenting with a delayed and prolonged coma due to an intentional overdose with disulfiram without simultaneous alcohol ingestion." | 7.75 | Delayed and prolonged coma after acute disulfiram overdose. ( Daems, J; Heytens, L; Lemoyne, S; Raemaekers, J, 2009) |
| "We report the case of a 35-year-old man presenting with a delayed and prolonged coma due to an intentional overdose with disulfiram without simultaneous alcohol ingestion." | 3.75 | Delayed and prolonged coma after acute disulfiram overdose. ( Daems, J; Heytens, L; Lemoyne, S; Raemaekers, J, 2009) |
| "A 49-year-old female with chronic alcoholism and epilepsy, treated with phenytoin, began to convulse when treatment with disulfiram (an inhibitor of phenytoin metabolism) was discontinued." | 3.65 | Multiple drug interactions with phenytoin. ( Birkett, DJ; Chinwah, PM; Graham, GG; Hickie, JB; Wade, DN, 1977) |
| "The behavioral and electrographic effects of DL-amphetamine, disulfiram, FLA-63, and propranolol on the photically induced epilepsy of the Senegalese baboon were evaluated." | 3.65 | Effects of drugs modifying brain levels of catecholamines on photically induced epilepsy in Papio papio. ( Brailowsky, S; Naquet, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lemoyne, S | 1 |
| Raemaekers, J | 1 |
| Daems, J | 1 |
| Heytens, L | 1 |
| Palmer, M | 1 |
| Olesen, OV | 1 |
| Krag, B | 1 |
| Dam, M | 1 |
| Angelo, H | 1 |
| Christensen, JM | 1 |
| Lamprecht, F | 1 |
| Birkett, DJ | 1 |
| Graham, GG | 1 |
| Chinwah, PM | 1 |
| Wade, DN | 1 |
| Hickie, JB | 1 |
| Brailowsky, S | 1 |
| Naquet, R | 1 |
| Loiseau, P | 1 |
| Brachet, A | 1 |
| Henry, P | 1 |
| Cenraud, P | 1 |
| Vercelletto, P | 1 |
| Friol-Vercelletto, M | 1 |
| Kutt, H | 1 |
| Penry, JK | 1 |
| Kiorboe, E | 1 |
| Gottwald, W | 1 |
2 reviews available for disulfiram and Epilepsy
| Article | Year |
|---|---|
Epilepsy and schizophrenia: a neurochemical bridge.
Topics: Amphetamine; Anticonvulsants; Brain; Butyrophenones; Disulfiram; Dopamine; Dopamine beta-Hydroxylase | 1977 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, G | 1974 |
1 trial available for disulfiram and Epilepsy
| Article | Year |
|---|---|
Phenytoin intoxication during treatment with antabuse (Disulfiram).
Topics: Adult; Alcoholism; Clinical Trials as Topic; Disulfiram; Drug Compounding; Drug Incompatibility; Epi | 1966 |
9 other studies available for disulfiram and Epilepsy
| Article | Year |
|---|---|
Delayed and prolonged coma after acute disulfiram overdose.
Topics: Adult; Alcohol Deterrents; Coma; Disulfiram; Drug Overdose; Epilepsy; Humans; Male; Neurotoxicity Sy | 2009 |
Combination treatment of epilepsy with ketogenic diet and concurrent pharmacological inhibition of cytochrome P450 2E1.
Topics: Animals; Child; Combined Modality Therapy; Cytochrome P-450 CYP2E1 Inhibitors; Diet, Ketogenic; Disu | 2013 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatogra | 1967 |
Influence of disulfiram on the serum concentration of carbamazepine in patients with epilepsy.
Topics: Adult; Carbamazepine; Disulfiram; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged | 1981 |
Multiple drug interactions with phenytoin.
Topics: Alcoholism; Disulfiram; Epilepsy; Female; Humans; Middle Aged; Phenytoin; Substance Withdrawal Syndr | 1977 |
Effects of drugs modifying brain levels of catecholamines on photically induced epilepsy in Papio papio.
Topics: Amphetamine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; D | 1976 |
[Letter: Diphenylhydrantoin poisoning during disulfiram therapy].
Topics: Adult; Alcoholism; Biotransformation; Disulfiram; Enzyme Inhibitors; Epilepsy; Humans; Liver; Male; | 1975 |
[Epilepsy in alcoholics].
Topics: Alcoholism; Disulfiram; Electroencephalography; Epilepsy; Humans; Liver Cirrhosis, Alcoholic; Tomogr | 1986 |
[Adverse effects of drugs in tuberculous patients. Allergic reactions due to isoniazid and hydantoins or disulfiram].
Topics: Alcoholism; Disulfiram; Drug Hypersensitivity; Drug Synergism; Epilepsy; Humans; Hydantoins; Isoniaz | 1970 |