Page last updated: 2024-11-05

zolpidem and Epilepsy

zolpidem has been researched along with Epilepsy in 9 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the impact of long-term zolpidem use on the subsequent risk of epilepsy."7.80Association of zolpidem use and subsequent increased risk of epilepsy: a population-based, case-control study. ( Harnod, T; Kao, CH; Sung, FC; Wang, YC, 2014)
"To evaluate the impact of long-term zolpidem use on the subsequent risk of epilepsy."3.80Association of zolpidem use and subsequent increased risk of epilepsy: a population-based, case-control study. ( Harnod, T; Kao, CH; Sung, FC; Wang, YC, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Castillo, JL1
Harnod, T1
Wang, YC1
Sung, FC1
Kao, CH1
Rajasekaran, K1
Sun, C1
Bertram, EH1
Heldt, SA1
Ressler, KJ1
Bowser, DN1
Wagner, DA1
Czajkowski, C1
Cromer, BA1
Parker, MW1
Wallace, RH1
Harkin, LA1
Mulley, JC1
Marini, C1
Berkovic, SF1
Williams, DA1
Jones, MV1
Petrou, S1
Tripodianakis, J1
Potagas, C1
Papageorgiou, P1
Lazaridou, M1
Matikas, N1
Levin, IaI1
Tarasov, BA1
Pericić, D1
Vlainić, J1
Strac, DS1
Hablitz, JJ1
DeFazio, RA1

Trials

1 trial available for zolpidem and Epilepsy

ArticleYear
[Influence of ivadal and depakene chrono on sleep structure in patients with epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:3

    Topics: Adult; Delayed-Action Preparations; Drug Administration Schedule; Electroencephalography; Electroocu

2003

Other Studies

8 other studies available for zolpidem and Epilepsy

ArticleYear
[Epileptic seizures after zolpidem withdrawal].
    Revista medica de Chile, 2020, Volume: 148, Issue:11

    Topics: Epilepsy; Humans; Hypnotics and Sedatives; Seizures; Zolpidem

2020
Association of zolpidem use and subsequent increased risk of epilepsy: a population-based, case-control study.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:10

    Topics: Adult; Aged; Case-Control Studies; Epilepsy; Female; Humans; Hypnotics and Sedatives; Male; Middle A

2014
Altered pharmacology and GABA-A receptor subunit expression in dorsal midline thalamic neurons in limbic epilepsy.
    Neurobiology of disease, 2009, Volume: 33, Issue:1

    Topics: Animals; Epilepsy; GABA Agents; Glutamate Decarboxylase; In Vitro Techniques; Inhibitory Postsynapti

2009
Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, May-26, Volume: 30, Issue:21

    Topics: Amygdala; Animals; Animals, Newborn; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cell Lin

2010
Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Nov-12, Volume: 99, Issue:23

    Topics: Amino Acid Substitution; Animals; Anti-Anxiety Agents; Cell Line; Diazepam; Epilepsy; Flunitrazepam;

2002
Zolpidem-related epileptic seizures: a case report.
    European psychiatry : the journal of the Association of European Psychiatrists, 2003, Volume: 18, Issue:3

    Topics: Adult; Electroencephalography; Epilepsy; Female; GABA Agonists; Humans; Pyridines; Substance Withdra

2003
Sedative and anticonvulsant effects of zolpidem in adult and aged mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:6

    Topics: Age Factors; Animals; Anticonvulsants; Brain; Convulsants; Diazepam; Disease Models, Animal; Dose-Re

2008
Altered receptor subunit expression in rat neocortical malformations.
    Epilepsia, 2000, Volume: 41 Suppl 6

    Topics: Animals; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Freezing; Neocortex;

2000