| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Becker Muscular Dystrophy
[description not available] | 0 | 2.99 | 4 | 0 |
Muscular Dystrophy, Animal
MUSCULAR DYSTROPHY that occurs in VERTEBRATE animals. | 0 | 2.78 | 3 | 0 |
Muscular Dystrophy, Duchenne
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415) | 0 | 2.99 | 4 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.77 | 3 | 0 |
Hyperkyphosis
[description not available] | 0 | 2.1 | 1 | 0 |
Muscular Dystrophy
[description not available] | 0 | 2.1 | 1 | 0 |
Cardiomyopathies, Primary
[description not available] | 0 | 2.1 | 1 | 0 |
Muscular Dystrophies
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS. | 0 | 2.1 | 1 | 0 |
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.1 | 1 | 0 |
HbS Disease
[description not available] | 0 | 8.31 | 10 | 3 |
Leg Ulcer
Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes. | 0 | 6.81 | 5 | 1 |
Anemia, Sickle Cell
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. | 0 | 8.31 | 10 | 3 |
EBV Infections
[description not available] | 0 | 8.3 | 6 | 1 |
Duncan Disease
[description not available] | 0 | 4.73 | 2 | 0 |
Lymphoproliferative Disorders
Disorders characterized by proliferation of lymphoid tissue, general or unspecified. | 0 | 4.73 | 2 | 0 |
Epstein-Barr Virus Infections
Infection with human herpesvirus 4 (HERPESVIRUS 4, HUMAN); which may facilitate the development of various lymphoproliferative disorders. These include BURKITT LYMPHOMA (African type), INFECTIOUS MONONUCLEOSIS, and oral hairy leukoplakia (LEUKOPLAKIA, HAIRY). | 0 | 8.3 | 6 | 1 |
Chronic Illness
[description not available] | 0 | 4.36 | 1 | 1 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 4.36 | 1 | 1 |
Leucocythaemia
[description not available] | 0 | 2.01 | 1 | 0 |
Germinoblastoma
[description not available] | 0 | 5.22 | 4 | 1 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 7.01 | 1 | 0 |
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 10.22 | 4 | 1 |
Addison Disease and Cerebral Sclerosis
[description not available] | 0 | 2.01 | 1 | 0 |
Adrenoleukodystrophy
An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS). | 0 | 7.01 | 1 | 0 |
Disease Exacerbation
[description not available] | 0 | 2.03 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.03 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.03 | 1 | 0 |
Benign Neoplasms
[description not available] | 0 | 1.96 | 1 | 0 |
Sarcoma 180
An experimental sarcoma of mice. | 0 | 2.65 | 3 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 1.96 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 1.96 | 1 | 0 |
Carcinoma, Ehrlich Tumor
A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. | 0 | 1.96 | 1 | 0 |
Experimental Leukemia
[description not available] | 0 | 1.96 | 1 | 0 |
Enterovirus Infections
Diseases caused by ENTEROVIRUS. | 0 | 1.96 | 1 | 0 |
Anemia, Cooley's
[description not available] | 0 | 4.47 | 5 | 1 |
beta-Thalassemia
A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. | 0 | 4.47 | 5 | 1 |
Aura
[description not available] | 0 | 1.98 | 1 | 0 |
Epilepsy
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 1.98 | 1 | 0 |
Hemoglobinopathies
A group of inherited disorders characterized by structural alterations within the hemoglobin molecule. | 0 | 2.9 | 1 | 0 |
Thalassemias
[description not available] | 0 | 1.98 | 1 | 0 |
Thalassemia
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. | 0 | 6.98 | 1 | 0 |
Acute Lymphoid Leukemia
[description not available] | 0 | 2.91 | 1 | 0 |
Aspergillus Infection
[description not available] | 0 | 2.91 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 4.71 | 2 | 0 |
Complication, Postoperative
[description not available] | 0 | 4.71 | 2 | 0 |
Aspergillosis
Infections with fungi of the genus ASPERGILLUS. | 0 | 2.91 | 1 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 4.71 | 2 | 0 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.91 | 1 | 0 |
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 4.71 | 2 | 0 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. | 0 | 2.91 | 1 | 0 |
Granulocytic Leukemia, Chronic
[description not available] | 0 | 1.99 | 1 | 0 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. | 0 | 1.99 | 1 | 0 |
Recrudescence
[description not available] | 0 | 1.99 | 1 | 0 |
Anoxemia
[description not available] | 0 | 1.99 | 1 | 0 |
Hypoxia
Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 1.99 | 1 | 0 |
Diffuse Mixed Small and Large Cell Lymphoma
[description not available] | 0 | 3.84 | 1 | 0 |
Lymphoma, Non-Hodgkin
Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 3.84 | 1 | 0 |
Acquired Immune Deficiency Syndrome
[description not available] | 0 | 2 | 1 | 0 |
Kaposi Sarcoma
[description not available] | 0 | 2 | 1 | 0 |
AIDS-Associated Lymphoma
[description not available] | 0 | 2 | 1 | 0 |
Acquired Immunodeficiency Syndrome
An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. | 0 | 2 | 1 | 0 |
Sarcoma, Kaposi
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. | 0 | 2 | 1 | 0 |
Lymphoma, AIDS-Related
B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation. | 0 | 2 | 1 | 0 |
Experimental Neoplasms
[description not available] | 0 | 2.37 | 2 | 0 |
Adrenal Cancer
[description not available] | 0 | 1.96 | 1 | 0 |