homocysteine has been researched along with Epilepsy in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (4.65) | 18.7374 |
| 1990's | 5 (5.81) | 18.2507 |
| 2000's | 39 (45.35) | 29.6817 |
| 2010's | 32 (37.21) | 24.3611 |
| 2020's | 6 (6.98) | 2.80 |
| Authors | Studies |
|---|---|
| Abd El Hady, NMS; Abdallah, HM; Abdelmageed, SM; Aboelghar, HM; Garib, MI; Mahmoud, AA | 1 |
| Duan, Z; Fang, Q; Hou, H; Sun, G; Tao, L; Zhang, S | 1 |
| Dai, Y; Wang, D; Zhang, X; Zou, R | 1 |
| Bilo, L; Bosso, G; De Luca, M; Oliviero, U; Pirone, D; Striano, P; Trinchillo, A; Valvano, A | 1 |
| Karatoprak, E; Ozer, I; Sozen, G; Yılmaz, K | 1 |
| Gong, Y; Liu, Y; Tao, H; Yu, Q; Zhou, H | 1 |
| Sharma, TK; Sitaraman, S; Vardey, SK | 3 |
| Ali, N; Nabi, M; Nazish, H; Shakir, S; Udin, Z | 1 |
| Ali, N; Nazish, H; Shakir, S | 1 |
| Chen, S; Xia, Z; Xu, H; Xu, S; Xu, Y; Zhang, N | 1 |
| Chen, D; Chen, L; Chen, P; Gao, X; Li, C; Li, H; Li, Y; Tian, Q; Tian, X; Wen, J; Yang, H; Zhang, M | 1 |
| Bjekić-Macut, J; Djuric, D; Hrncić, D; Rasić-Marković, A; Stanojlović, O; Susić, V | 1 |
| Kim, DW; Kim, JH; Lee, SY; Shon, YM | 1 |
| Alibrandi, A; Caccamo, D; Di Rosa, G; Germanò, E; Guerrera, S; Lenzo, P; Neri, M; Nicotera, A; Parisi, E; Spanò, M; Tortorella, G | 1 |
| Darteyre, S; Fichtner, C; Gay, C; Ged, C; Saboul, C; Stephan, JL | 1 |
| Keenan, N; Sadlier, LG; Wiltshire, E | 1 |
| Chen, Y; Chen, Z; Fang, Z; Ni, G; Qin, J; Zhou, J; Zhou, L | 1 |
| Gan, SH; Shaik, MM | 1 |
| Chen, Y; Chen, Z; Fang, Z; Huang, M; Li, H; Ni, G; Qin, J; Zhou, J; Zhou, L; Zhou, Y | 1 |
| Djuric, D; Hrnčić, D; Rašić-Marković, A; Šćepanović, L; Stanojlović, O; Stojanović, M | 1 |
| Mendioroz Iriarte, M; Muruzabal Pérez, J; Pulido Fontes, L; Pulido Fontes, M; Quesada Jiménez, P | 1 |
| Abdulahi Abdurahman, A; Djafarian, K; Rezaei, S; Shab-Bidar, S | 1 |
| Caccamo, D; Currò, M; Gorgone, G; Ientile, R; Oteri, G; Parisi, G; Pisani, F; Pisani, LR; Rossini, PM | 1 |
| Akar, N; Deda, G; Ertem, M; Teber, S; Unal, O | 1 |
| Belcastro, V; Striano, P | 2 |
| Abidin, CJ; Capuzzi, DM; Chervoneva, I; Mintzer, S; Morales, MC; Skidmore, CT; Sperling, MR | 1 |
| Druga, R; Folbergrová, J; Haugvicová, R; Otáhal, J; Tsenov, G | 1 |
| Arhan, E; Guven, A; Köse, G; Ozaydin, E; Sayli, TR; Unal, B | 1 |
| Bek, S; Cakir, E; Gökçil, Z; Odabaşi, Z; Oz, O | 1 |
| Folbergrová, J; Haugvicová, R; Houstek, J; Jesina, P; Lisý, V | 1 |
| Dorszewska, J; Kaczmarek, I; Sniezawska, A; Steinborn, B; Winczewska-Wiktor, A | 1 |
| Cheng, LS; Prasad, AN; Rieder, MJ | 1 |
| Aydogdu, SD; Colak, O; Dinleyici, EC; Ozdemir, O; Yakut, A; Yarar, C | 1 |
| Dorszewska, J; Jagodzinski, PP; Kozubski, W; Lianeri, M; Przedpelska-Ober, E; Rozycka, A; Sniezawska, A | 1 |
| Chan, SH; Chang, CC; Chang, WN; Chen, SD; Chuang, HY; Chuang, YC; Huang, CR; Lin, TK; Lu, CH; Tan, TY | 1 |
| Akgün, H; Gökçil, Z; Odabaşi, Z; Oz, O; Yücel, M | 1 |
| Bochyńska, A; Graban, A; Gugała-Iwaniuk, M; Lechowicz, W; Lipczyńska-Łojkowska, W; Lipska, B; Restel, M; Ryglewicz, D | 1 |
| Borowczyk, K; Jakubowski, H; Shih, DM | 1 |
| Barone, E; Coppola, G; Ingrosso, D; Lattanzio, F; Matera, S; Operto, FF; Signoriello, G; Verrotti, A | 1 |
| Carroll, WD; Clifford, H; Emes, RD; Farrell, WE; Fryer, AA; Haworth, KE; Ismail, KM | 1 |
| Aggarwal, A; Chillar, N; Faridi, MM; Kumar, V; Mittal, H; Sharma, S | 1 |
| Arga, M; Arhan, E; Biberoglu, G; Cansu, A; Emeksiz, HC; Gulbahar, O; Hasanoglu, A; Serdaroglu, A | 1 |
| Elger, C; Linnebank, M; Moskau-Hartmann, S; Semmler, A; Stoffel-Wagner, B | 1 |
| Haugvicová, R; Kubová, H; Mares, P | 1 |
| Apeland, T; Mansoor, MA; McNulty, H; Pentieva, K; Seljeflot, I; Strandjord, RE | 1 |
| Aksoy, E; Biberoğlu, G; Hasanoğlu, A; Serdaroğlu, A; Tümer, L | 1 |
| Karabiber, H; Otlu, B; Ozerol, E; Sonmezgoz, E; Yakinci, C; Yologlu, S | 1 |
| Kojima, K; Maekawa, T; Monji, A; Sumida, Y; Yamazaki, K; Yanagimoto, K | 1 |
| Gidal, BE; Hammer, A; Tamura, T; Vuong, A | 1 |
| Biagio Mercuri, N; De Sarro, G; Ferreri Ibbadu, G; Gallelli, L; Mancuso, F; Siniscalchi, A | 1 |
| Moore, JL | 1 |
| Hamed, SA; Nabeshima, T | 1 |
| Ausserer, B; Graninger, G; Hubmann, M; Huemer, C; Huemer, M; Schlachter, K; Simma, B; Tscharre, A; Ulmer, H | 1 |
| Coker, I; Karaguzel, O; Ozdamar, O; Sener, U; Topbas, M; Zorlu, Y | 1 |
| Attilakos, A; Garoufi, A; Katsarou, E; Mastroyianni, S; Papakonstantinou, E; Schulpis, K; Voudris, K | 1 |
| Elliott, JO; Haneef, Z; Jacobson, MP | 2 |
| Boisson, C; Candito, M; Gaucherand, P; Guéant, JL; Luton, D; Naimi, M; Rudigoz, JC; Van Obberghen, E | 1 |
| Choi, D; Harris, RH; Kohn, H; Kupferberg, HJ; Stables, JP; Stöhr, T; Walton, N; White, HS | 1 |
| Kampman, MT | 1 |
| Herrmann, W; Obeid, R | 1 |
| Belcastro, V; Caccamo, D; Gaetano, G; Ientile, R; Italiano, D; Oteri, G; Pisani, F; Pisani, LR; Striano, P; Striano, S | 1 |
| Badiou, S; Breton, H; Charasson, V; Crespel, A; Cristol, JP; Gelisse, P; Hillaire-Buys, D; Peyriere, H | 1 |
| Kurul, S; Unalp, A; Yiş, U | 1 |
| Aslan, K; Bozdemir, H; Güvenc, B; Unsal, C | 1 |
| Akin, R; Demirkaya, E; Gokçay, E; Gul, D; Kul, M; Unay, B; Vurucu, S | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Eguchi, T; Fujita, N; Nomura, S; Ono, H; Sakamoto, A; Sakura, N; Ueda, H; Ueda, K | 1 |
| James, GK; Jones, MW; Pudek, MR | 1 |
| Fiehn, W; Kohl, B; Rieser, PA; Ringleb, P; Schwaninger, M; Walter-Sack, I; Winter, R | 1 |
| Artuch, R; Campistol, J; Cardo, E; Colomé, C; Pineda, M; Vilaseca, MA | 1 |
| Folbergrová, J; Haugvicová, R; Mares, P | 2 |
| Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Chiarelli, F; Giuva, T; Morgese, G; Pascarella, R; Trotta, D; Verrotti, A | 1 |
| Diaz-Arrastia, R | 1 |
| Apeland, T; Mansoor, MA; Strandjord, RE | 1 |
| Afeltra, A; Amoroso, A; Del Porto, F; Francia, A; Galluzzo, S; Gandolfo, GM; Mitterhofer, AP; Vadacca, M | 1 |
| Biancheri, R; Caruso, U; Cerone, R; Minniti, G; Perrone, MV; Rossi, A; Schiaffino, MC; Tortori-Donati, P; Veneselli, E | 1 |
| Johansson, B; Nilsson, B | 1 |
| Audinat, E; Cuénod, M; Do, KQ; Gähwiler, BH; Grandes, P; Herrling, P; Knöpfel, T; Perschak, H; Streit, P; Vollenweider, F | 1 |
| Allen, IC; Grieve, A; Griffiths, R | 1 |
| Brett, EM | 1 |
14 review(s) available for homocysteine and Epilepsy
| Article | Year |
|---|---|
Effects of phenytoin on serum levels of homocysteine, vitamin B12, folate in patients with epilepsy: A systematic review and meta-analysis (PRISMA-compliant article).
Topics: Anticonvulsants; Epilepsy; Folic Acid; Homocysteine; Humans; Phenytoin; Research Design; Vitamin B 12 | 2019 |
CPS1 T1405N polymorphism, HDL cholesterol, homocysteine and renal function are risk factors of VPA induced hyperammonemia among epilepsy patients.
Topics: Anticonvulsants; Carbamoyl-Phosphate Synthase (Ammonia); Case-Control Studies; Cholesterol, HDL; Epilepsy; Homocysteine; Humans; Hyperammonemia; Kidney; Polymorphism, Genetic; Risk Factors; Valproic Acid | 2019 |
Increased homocysteine levels in valproate-treated patients with epilepsy: a meta-analysis.
Topics: Anticonvulsants; Epilepsy; Homocysteine; Humans; Valproic Acid | 2014 |
Vitamin supplementation as possible prophylactic treatment against migraine with aura and menstrual migraine.
Topics: Adult; Ascorbic Acid; Epilepsy; Female; Folic Acid; Genotype; Homocysteine; Humans; Menstruation; Migraine Disorders; Migraine with Aura; Vitamin B 12; Vitamin B 6; Vitamin E | 2015 |
Multidisciplinary approach to nitric oxide signaling: Focus on the gastrointestinal and the central nervous system.
Topics: Animals; Central Nervous System; Enteric Nervous System; Epilepsy; Gastrointestinal Tract; Homocysteine; Humans; Muscle, Smooth; Nitrergic Neurons; Nitric Oxide; Synaptic Transmission | 2015 |
Oxcarbazepine administration and the serum levels of homocysteine, vitamin B12 and folate in epileptic patients: A systematic review and meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Folic Acid; Homocysteine; Humans; Oxcarbazepine; Vitamin B 12 | 2017 |
[Homocysteine and asymmetric dimethylarginine (ADMA) in epilepsy].
Topics: Anticonvulsants; Arginine; Carbamazepine; Epilepsy; Homocysteine; Humans; Nitric Oxide; Nitric Oxide Synthase; Valproic Acid | 2009 |
Relationship between antiepileptic drugs and biological markers affecting long-term cardiovascular function in children and adolescents.
Topics: Adolescent; Anticonvulsants; Biomarkers, Pharmacological; Cardiovascular Diseases; Child; Epilepsy; Homocysteine; Humans; Lipoproteins; Methylenetetrahydrofolate Reductase (NADPH2); Time Factors | 2010 |
Antiepileptic drugs, hyperhomocysteinemia and B-vitamins supplementation in patients with epilepsy.
Topics: Anticonvulsants; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2012 |
Increase in plasma homocysteine levels induced by drug treatments in neurologic patients.
Topics: Cerebrovascular Disorders; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Parkinson Disease; Vitamins | 2005 |
The significance of folic acid for epilepsy patients.
Topics: Anticonvulsants; Epilepsy; Female; Folic Acid; History, 20th Century; Homocysteine; Humans; Male; Methionine; Models, Biological; Neural Tube Defects; Pregnancy; Vascular Diseases | 2005 |
The high atherosclerotic risk among epileptics: the atheroprotective role of multivitamins.
Topics: Antioxidants; Arteriosclerosis; Epilepsy; Female; Homocysteine; Humans; Lipid Metabolism; Lipids; Lipoproteins; Male; Oxidative Stress; Risk Factors; Uric Acid; Vitamins | 2005 |
Homocysteine and neurologic disease.
Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Pyridoxine; Vascular Diseases; Vitamin B 12 | 2000 |
Homocysteic acid as transmitter candidate in the mammalian brain and excitatory amino acids in epilepsy.
Topics: Amino Acids; Animals; Brain; Epilepsy; Homocysteine; Humans; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate | 1990 |
7 trial(s) available for homocysteine and Epilepsy
| Article | Year |
|---|---|
Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein.
Topics: Adolescent; Adult; Aged; Anticonvulsants; C-Reactive Protein; Case-Control Studies; Epilepsy; Fasting; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Young Adult | 2009 |
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Valproic Acid; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
The effect of B-vitamins on hyperhomocysteinemia in patients on antiepileptic drugs.
Topics: Adult; Anticonvulsants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; Middle Aged; Pyridoxic Acid; Riboflavin; Selectins; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2002 |
Hyperhomocysteinemia in children treated with antiepileptic drugs is normalized by folic acid supplementation.
Topics: Anticonvulsants; Child; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Treatment Outcome; Vitamin B 12 | 2005 |
Comparison of carbamazepine and oxcarbazepine effects on aminothiol levels.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Cysteine; Dipeptides; Epilepsy; Female; Homocysteine; Humans; Male; Middle Aged; Oxcarbazepine; Risk Factors | 2008 |
Homocyst(e)ine levels in patients on phenytoin therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Epilepsy; Female; Homocysteine; Humans; Male; Middle Aged; Phenytoin | 1997 |
Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsy; Female; Homocysteine; Humans; Male; Valproic Acid | 2000 |
65 other study(ies) available for homocysteine and Epilepsy
| Article | Year |
|---|---|
Assessment of asymmetric dimethylarginine and homocysteine in epileptic children receiving antiepileptic drugs.
Topics: Anticonvulsants; Arginine; Carotid Intima-Media Thickness; Child; Epilepsy; Homocysteine; Humans; Levetiracetam; Valproic Acid | 2022 |
Clinical characteristics of cognitive impairment and its related risk factors in post-stroke epilepsy
Topics: Adult; Anticonvulsants; Brain Ischemia; Cognitive Dysfunction; Epilepsy; Homocysteine; Humans; Risk Factors; Stroke | 2022 |
Association between MTHFR polymorphism and seizure control in epileptic patients with hyperhomocysteinaemia
Topics: Epilepsy; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Seizures; Vitamin B 12; Vitamins | 2022 |
Effects of three-months folate supplementation on early vascular abnormalities in hyperhomocysteinemic patients with epilepsy.
Topics: Dietary Supplements; Epilepsy; Folic Acid; Homocysteine; Humans; Matrix Metalloproteinase 9; Tissue Inhibitor of Metalloproteinase-1 | 2022 |
Interictal epileptiform discharges on electroencephalography in children with methylenetetrahydrofolate reductase (MTHFR) polymorphisms.
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vitamin B 12 | 2020 |
Elevated Serum Matrix Metalloproteinase-9, Interleukin-6, Hypersensitive C-Reactive Protein, and Homocysteine Levels in Patients with Epilepsy.
Topics: Adolescent; Adult; Aged; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Epilepsy; Female; Homocysteine; Humans; Interleukin-6; Male; Matrix Metalloproteinase 9; Middle Aged; Young Adult | 2020 |
Homocysteine Metabolism and Hematological Parameters in Early Stage of Phenytoin Treated Epileptic Children.
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phenytoin; Vitamin B 12 | 2017 |
Vitamin B
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsy; Female; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pakistan; Polymorphism, Single Nucleotide; Receptors, GABA-A; Vitamin B 6; Young Adult | 2017 |
Carbamazepine Verses Valproic Acid as Monotherapy in Epileptic Patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Chromatography, Liquid; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Seizures; Severity of Illness Index; Treatment Outcome; Valproic Acid; Vitamin B 6; Young Adult | 2018 |
Paradoxical sleep deprivation potentiates epilepsy induced by homocysteine thiolactone in adult rats.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy; Homocysteine; Male; Rats; Rats, Wistar; Sleep Deprivation; Sleep, REM | 2013 |
Effects of new antiepileptic drugs on circulatory markers for vascular risk in patients with newly diagnosed epilepsy.
Topics: Adult; Anticonvulsants; Apolipoprotein A-I; Apolipoproteins B; Atherosclerosis; Biomarkers; Carbamazepine; Cholesterol, LDL; Epilepsy; Female; Fructose; Homocysteine; Humans; Levetiracetam; Male; Oxcarbazepine; Piracetam; Prospective Studies; Risk Factors; Topiramate | 2013 |
Role of plasma homocysteine levels and MTHFR polymorphisms on IQ scores in children and young adults with epilepsy treated with antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Child; Cognition Disorders; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Intelligence Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Polymorphism, Genetic; Statistics, Nonparametric; Vitamin B 12; Young Adult | 2013 |
Inaugural cerebral sinovenous thrombosis revealing homocystinuria in a 2-year-old boy.
Topics: Anticonvulsants; Brain; Cavernous Sinus Thrombosis; Child, Preschool; Electroencephalography; Epilepsy; Gadolinium; Homocysteine; Homocystinuria; Humans; Magnetic Resonance Angiography; Male; Psychomotor Disorders; Tomography Scanners, X-Ray Computed | 2015 |
Vascular function and risk factors in children with epilepsy: associations with sodium valproate and carbamazepine.
Topics: Adolescent; Anticonvulsants; Aorta; Blood Glucose; Brachial Artery; Carbamazepine; Carotid Arteries; Cholesterol; Cholesterol, HDL; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phosphoric Monoester Hydrolases; Risk Factors; Ultrasonography; Valproic Acid; Vitamin B 12 | 2014 |
Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Cross-Sectional Studies; DNA Methylation; Epilepsy; Female; Folic Acid; Heterocyclic Compounds; Homocysteine; Humans; Lamotrigine; Long Interspersed Nucleotide Elements; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Triazines; Valproic Acid; Vitamin B 12; Young Adult | 2015 |
Evaluate the Effect of Valproate Monotherapy on the Serum Homocysteine, Folate and Vitamin B12 Levels in Epileptic Children.
Topics: Adolescent; Age Factors; Anticonvulsants; Case-Control Studies; Child; Child, Preschool; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Time Factors; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2015 |
Comparative case-control study of homocysteine, vitamin B
Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2017 |
Serum Homocysteine, Folate, and Vitamin B12 Levels in Carbamazepine Treated Epileptic Children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2016 |
Hyperhomocysteinemia in patients with epilepsy: does it play a role in the pathogenesis of brain atrophy? A preliminary report.
Topics: Adolescent; Adult; Atrophy; Brain; Epilepsy; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxidative Stress | 2009 |
Thrombophilic risk factors in epileptic children treated with valproic Acid.
Topics: Adolescent; Anticonvulsants; Antithrombin III; Blood Coagulation Factors; Child; Child, Preschool; Epilepsy; Female; Fibrinogen; Homocysteine; Humans; Infant; Lipoprotein(a); Male; Protein C; Protein S; Prothrombin; Risk Factors; Thrombophilia; Valproic Acid | 2009 |
Commentary to: "Evaluation of serum lipids and carotid artery intima media thickness in epileptic children treated with valproic acid".
Topics: Age Factors; Anticonvulsants; Carotid Stenosis; Child; Endothelial Cells; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Lipid Metabolism Disorders; Risk Factors; Tunica Intima; Valproic Acid | 2009 |
Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats.
Topics: Aging; Animals; Brain; Convulsants; Cytoprotection; Drug Administration Schedule; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Male; Nerve Degeneration; Neuroprotective Agents; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Treatment Outcome | 2009 |
Valproate-associated coagulopathies in children during short-term treatment.
Topics: Adolescent; Anticonvulsants; Biomarkers; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Protein Disorders; Child; Child, Preschool; Down-Regulation; Drug Administration Schedule; Epilepsy; Factor VII; Factor VIII; Female; Fibrinogen; Homocysteine; Humans; Lipoprotein(a); Male; Platelet Count; Prospective Studies; Protein C; Valproic Acid | 2009 |
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?
Topics: Adult; Anticonvulsants; Arginine; Arterial Occlusive Diseases; Carbamazepine; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Statistics, Nonparametric; Valproic Acid; Vitamin B 12 | 2009 |
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid.
Topics: Aldehydes; Animals; Animals, Newborn; Cerebral Cortex; Convulsants; Disease Models, Animal; Down-Regulation; Electron Transport Complex I; Energy Metabolism; Epilepsy; Excitatory Amino Acid Agonists; Free Radical Scavengers; Homocysteine; Male; Metabolic Networks and Pathways; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Rats; Rats, Wistar; Seizures; Survival Rate; Time Factors; Tyrosine | 2010 |
Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid.
Topics: Adolescent; Anticonvulsants; Arginine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cholesterol; Cross-Sectional Studies; Drug Administration Schedule; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Triglycerides; Valproic Acid; Vitamin B 12; Vitamin B Complex | 2011 |
MTHFR, MTR, and MTHFD1 gene polymorphisms compared to homocysteine and asymmetric dimethylarginine concentrations and their metabolites in epileptic patients treated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Arginine; Epilepsy; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Genetic | 2011 |
Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Atherosclerosis; Blood Glucose; Carbamazepine; Carotid Artery, Common; Cross-Sectional Studies; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Risk Factors; Time Factors; Uric Acid; Valproic Acid; Young Adult | 2012 |
Increased asymmetric dimethylarginine level after antiepileptic drug treatment may be independent of the changes in plasma homocysteine level.
Topics: Anticonvulsants; Arginine; Epilepsy; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2) | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen | 2012 |
Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2012 |
Antiepileptic drugs and the fetal epigenome.
Topics: Anticonvulsants; Birth Weight; Case-Control Studies; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Epilepsy; Female; Fetal Blood; Fetus; Folic Acid; Homocysteine; Humans; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnancy Complications | 2013 |
Effect of carbamazepine therapy on homocysteine, vitamin B12 and folic acid levels in children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Neurocysticercosis; Prospective Studies; Vitamin B 12 | 2013 |
Assessment of atherosclerosis risk due to the homocysteine-asymmetric dimethylarginine-nitric oxide cascade in children taking antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Arginine; Atherosclerosis; Biomarkers; Carbamazepine; Child; Epilepsy; Female; Homocysteine; Humans; Male; Nitric Oxide; Oxcarbazepine; Prospective Studies; Risk Factors; Valproic Acid | 2013 |
Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anticonvulsants; Cystathionine beta-Synthase; Epilepsy; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12 | 2013 |
Interaction of excitatory amino acid agonists with cortical afterdischarges in developing rats.
Topics: Aging; Animals; Cerebral Cortex; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Homocysteine; Kainic Acid; N-Methylaspartate; Rats; Rats, Wistar | 2002 |
Plasma homocysteine and lipoprotein (a) levels as risk factors for atherosclerotic vascular disease in epileptic children taking anticonvulsants.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Arteriosclerosis; Biomarkers; Case-Control Studies; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Homocysteine; Humans; Lipoprotein(a); Male; Probability; Prognosis; Reference Values; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric | 2002 |
Effects of valproate and carbamazepine on serum levels of homocysteine, vitamin B12, and folic acid.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Valproic Acid; Vitamin B 12 | 2003 |
Plasma folate and homocysteine levels may be related to interictal "schizophrenia-like" psychosis in patients with epilepsy.
Topics: Adult; Electroencephalography; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenic Psychology; Vitamin B 12 | 2005 |
Blood homocysteine, folate and vitamin B-12 concentrations in patients with epilepsy receiving lamotrigine or sodium valproate for initial monotherapy.
Topics: Adult; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid; Vitamin B 12 | 2005 |
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Pyridoxal Phosphate; Reference Values; Valproic Acid; Vitamin B 12 | 2006 |
Early effect of sodium valproate and carbamazepine monotherapy on homocysteine metabolism in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Prospective Studies; Pyridoxal Phosphate; Valproic Acid; Vitamin B 12 | 2006 |
Homocysteine and bone loss in epilepsy.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticonvulsants; Blood Urea Nitrogen; Bone Density; Bone Diseases, Metabolic; Calcium; Epilepsy; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Regression Analysis; Spine | 2007 |
Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Vitamin B 12; Vitamin B 6 | 2007 |
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
Topics: Acetamides; Animals; Anticonvulsants; Bicuculline; Cobalt; Convulsants; Electroshock; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Reflex; Excitatory Amino Acid Agonists; GABA Antagonists; Homocysteine; Kindling, Neurologic; Lacosamide; Male; Mice; N-Methylaspartate; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2007 |
Folate status in women of childbearing age with epilepsy.
Topics: Adolescent; Adult; Chi-Square Distribution; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Surveys and Questionnaires | 2007 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.
Topics: Aquaporins; Brain; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Muscular Dystrophy, Duchenne; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Antiepileptic drugs and MTHFR polymorphisms influence hyper-homocysteinemia recurrence in epileptic patients.
Topics: Adult; Age Factors; Anticonvulsants; Combined Modality Therapy; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2007 |
Cardiovascular risk factors and homocysteine in epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Body Mass Index; Cardiovascular Diseases; Epilepsy; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Meta-Analysis as Topic; Middle Aged; Prevalence; Risk Factors; Smoking | 2007 |
Homocysteine levels in epileptic children receiving antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Oxcarbazepine; Valproic Acid; Vitamin B 12 | 2007 |
The effect of antiepileptic drugs on vitamin B12 metabolism.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Case-Control Studies; Epilepsy; Erythrocytes, Abnormal; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neutrophils; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Electrochemistry; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Valproic Acid; Vitamin B 12 | 2008 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Plasma total homocysteine concentrations in epileptic patients taking anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Male; Vitamin B 12 | 1997 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Evaluation of hyperhomocysteinaemia in children with stroke.
Topics: Adolescent; Anticonvulsants; Cerebrovascular Disorders; Child; Child, Preschool; Chromatography, High Pressure Liquid; Epilepsy; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Odds Ratio; Risk Assessment | 1999 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Cyclobutanes; Cyclopropanes; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Glycine; Homocysteine; Male; Neuroprotective Agents; Organophosphorus Compounds; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures | 2001 |
Antiepileptic drugs as independent predictors of plasma total homocysteine levels.
Topics: Adult; Amino Acid Substitution; Anticonvulsants; Cholesterol; Cholesterol, HDL; Confidence Intervals; Cysteine; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Predictive Value of Tests; Prevalence; Statistics, Nonparametric; Threonine; Triglycerides; Vitamin B 12 | 2001 |
The 677C --> T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in epileptic patients affected by systemic lupus erythematosus.
Topics: Adolescent; Adult; Antibodies, Anticardiolipin; Epilepsy; Female; Gene Expression; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoglobulin G; Immunoglobulin M; Lupus Coagulation Inhibitor; Lupus Erythematosus, Systemic; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Protein S | 2002 |
Early-onset cobalamin C/D deficiency: epilepsy and electroencephalographic features.
Topics: Age of Onset; Brain; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Sleep; Vitamin B 12; Vitamin B 12 Deficiency; Wakefulness | 2002 |
The pathophysiology of the blood-brain barrier dysfunction induced by severe hypercapnia and by epileptic brain activity.
Topics: Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Epilepsy; Homocysteine; Hypercapnia; Hypertension; Male; Permeability; Phentolamine; Proteins; Rats | 1977 |
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Homocysteine; Hypothalamus; Inferior Colliculi; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Substantia Nigra; Taurine; Tissue Distribution | 1986 |
Homocystinuria with epilepsy.
Topics: Child; Cystinuria; Electroencephalography; Epilepsy; Homocysteine; Homocystinuria; Humans; Male; Urine | 1966 |