Page last updated: 2024-11-08

biguanides and Epilepsy

biguanides has been researched along with Epilepsy in 3 studies

Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin."5.04Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wada, Y1
Shiraishi, J1
Nakamura, M1
Koshino, Y1
Russell, BG1
Bay, LM1
Poli, S1
Vincent, A1
Perret, C1

Reviews

1 review available for biguanides and Epilepsy

ArticleYear
[Lactic acidosis].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:1

    Topics: Acidosis; Bicarbonates; Biguanides; Diabetes Mellitus; Epilepsy; Ethanol; Fructose; Heart Failure; H

1985

Trials

1 trial available for biguanides and Epilepsy

ArticleYear
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
    Scandinavian journal of dental research, 1978, Volume: 86, Issue:1

    Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial

1978

Other Studies

1 other study available for biguanides and Epilepsy

ArticleYear
Effects of the 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide in the rat kindling model of epilepsy.
    Brain research, 1997, Jun-13, Volume: 759, Issue:2

    Topics: Amygdala; Animals; Biguanides; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; K

1997