chloroquine has been researched along with Epilepsy in 17 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goal of this systematic review is to assess the published literature for seizure risk with chloroquine or hydroxychloroquine therapy in persons with and without epilepsy." | 7.96 | Assessing the risk of seizures with chloroquine or hydroxychloroquine therapy for COVID-19 in persons with epilepsy. ( Houston, T; Pati, S, 2020) |
| "The goal of this systematic review is to assess the published literature for seizure risk with chloroquine or hydroxychloroquine therapy in persons with and without epilepsy." | 3.96 | Assessing the risk of seizures with chloroquine or hydroxychloroquine therapy for COVID-19 in persons with epilepsy. ( Houston, T; Pati, S, 2020) |
| " However, management of acute seizures in patients with COVID-19 as well as management of PWE and COVID-19 needs to consider potential drug-drug interactions between antiseizure drugs and candidate drugs currently assessed as therapeutic options for COVID-19." | 2.72 | Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications. ( Chandra, PP; Jain, S; Potschka, H; Tripathi, M; Vohora, D, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Pati, S | 1 |
| Houston, T | 1 |
| Atakla, HG | 1 |
| Noudohounsi, ACWH | 1 |
| Barry, LF | 1 |
| Noudohounsi, MMUD | 1 |
| Legba, LD | 1 |
| Souare, IS | 1 |
| Kaba, F | 1 |
| Houinato, DS | 1 |
| Jain, S | 1 |
| Potschka, H | 1 |
| Chandra, PP | 1 |
| Tripathi, M | 1 |
| Vohora, D | 1 |
| Richens, A | 1 |
| Andrews, C | 1 |
| KAUFMANN, M | 1 |
| VAZQUEZ, HJ | 1 |
| HOJMAN, N | 1 |
| QUIROGA, FE | 1 |
| TAEN, S | 1 |
| KAZAMATSURI, H | 1 |
| GOTO, Y | 1 |
| TOKUDA, T | 1 |
| MARUNO, H | 1 |
| MOTEGI, A | 1 |
| WADA, T | 2 |
| YOSHIDA, T | 1 |
| GOTO, A | 1 |
| SAKURADA, S | 1 |
| SULLI, G | 1 |
| VARRONE, F | 1 |
| MIZUNO, T | 1 |
| NAMBA, H | 1 |
| INOUE, A | 1 |
| Guilloton, L | 2 |
| Drouet, A | 2 |
| Renoult, PA | 1 |
| Bedubourg, G | 1 |
| Vial, T | 1 |
| Felten, D | 2 |
| Amabeoku, GJ | 1 |
| Chikuni, O | 1 |
| Burchard, GD | 1 |
| Bauer, J | 1 |
| Burckard, E | 1 |
| Fresse, S | 1 |
| Torrey, EF | 1 |
4 reviews available for chloroquine and Epilepsy
| Article | Year |
|---|---|
Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications.
Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanize | 2021 |
Clinical practice: antimalarial prophylaxis in patients with epilepsy [corrected].
Topics: Antimalarials; Chemoprevention; Chloroquine; Epilepsy; Humans; Malaria; Mefloquine; Risk Factors; Tr | 2002 |
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy; | 1963 |
[Recommendations for prevention of malaria in patients with epilepsy].
Topics: Adolescent; Adult; Aged; Antimalarials; Chloroquine; Electroencephalography; Epilepsy; Female; Human | 2001 |
13 other studies available for chloroquine and Epilepsy
| Article | Year |
|---|---|
Assessing the risk of seizures with chloroquine or hydroxychloroquine therapy for COVID-19 in persons with epilepsy.
Topics: Adolescent; Adult; Aged; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Dr | 2020 |
COVID-19 infection in known epileptic and non-epileptic children: what is the place of chloroquine sulfate? (a case report).
Topics: Adolescent; Child; Chloroquine; COVID-19; COVID-19 Drug Treatment; Electroencephalography; Epilepsy; | 2020 |
[Successful treatment of petit mal with chloroquine (aralen)].
Topics: Chloroquine; Epilepsy | 1958 |
[Observations on quinacrine & chloroquine in the treatment of petit mal; preliminary report].
Topics: Chloroquine; Epilepsy; Epilepsy, Absence; Quinacrine | 1959 |
[Effects of chloroquine diorotate on epileptic seizures].
Topics: Chloroquine; Epilepsy; Humans | 1963 |
Chloroquine treatment in refractory epilepsy: clinical and electroencephalographic results.
Topics: Chloroquine; Electroencephalography; Epilepsy; Humans | 1962 |
[Combined treatment with chloroquinoline diphosphate and anticonvulsants for refractory epilepsy: an approach to a new therapeutic method].
Topics: Anticonvulsants; Chloroquine; Combined Modality Therapy; Diphosphates; Epilepsy; Manipulation, Osteo | 1961 |
[DIAGNOSIS AND THERAPY OF CONVULSIVE DISEASES IN CHILDHOOD].
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Amino Acids; Barbiturates; Brain Diseases; C | 1964 |
[TREATMENT OF EPILEPSY WITH RESOCHIN].
Topics: Anticonvulsants; Chloroquine; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Hum | 1965 |
[Oxcarbazepine-induced encephalopathy].
Topics: Adult; Anticonvulsants; Antimalarials; Carbamazepine; Chloroquine; Confusion; Epilepsy; Female; Huma | 2003 |
Chloroquine-induced seizures in mice: the role of monoaminergic mechanisms.
Topics: Animals; Biogenic Monoamines; Chloroquine; Epilepsy; Male; Mice; Mice, Inbred Strains; Reaction Time | 1993 |
[Epileptic crisis after antimalaria chemoprophylaxis with chloroquine].
Topics: Anti-Anxiety Agents; Anticonvulsants; Antimalarials; Benzodiazepines; Chloroquine; Clobazam; Epileps | 2001 |
Chloroquine seizures. Report of four cases.
Topics: Adult; Chloroquine; Dysentery, Amebic; Epilepsy; Female; Hepatitis; Humans; Malaria | 1968 |