1-methyl-3-isobutylxanthine has been researched along with Epilepsy in 4 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alam, AM | 1 |
| Starr, MS | 1 |
| De Sarro, A | 1 |
| Grasso, S | 1 |
| Zappala, M | 1 |
| Nava, F | 1 |
| De Sarro, G | 1 |
| Apland, JP | 1 |
| Helekar, SA | 1 |
| Lebeda, FJ | 1 |
| Hattori, Y | 1 |
| Moriwaki, A | 1 |
| Hayashi, Y | 1 |
| Hori, Y | 1 |
4 other studies available for 1-methyl-3-isobutylxanthine and Epilepsy
| Article | Year |
|---|---|
D1 agonists suppress zero Mg(2+)-induced epileptiform activity in the rat cingulate cortex slice.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Be | 1993 |
Convulsant effects of some xanthine derivatives in genetically epilepsy-prone rats.
Topics: 1-Methyl-3-isobutylxanthine; Acoustic Stimulation; Animals; Caffeine; Convulsants; Dyphylline; Elect | 1997 |
Suppression of drug-induced epileptiform discharges by cyclic AMP in rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 5'-Nucleotidase; Animals; B | 1997 |
Cyclic AMP levels in slices of epileptic cortex of the rat: effects of glutamate and 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cerebral Cortex; Cyclic AMP; Electroencephalography; Epilepsy; | 1986 |