Page last updated: 2024-10-20

taurine and Epilepsy

taurine has been researched along with Epilepsy in 92 studies

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"An experimental model based on kainic acid (KA) injections replicates many phenomenological features of human temporal lobe epilepsy, the most common type of epilepsy in adults."7.75Prevention of epilepsy by taurine treatments in mice experimental model. ( Auladell, C; Camins, A; Duque, D; Junyent, F; Pallàs, M; Romero, R; Utrera, J, 2009)
"The potential role of taurine on epilepsy and acupuncture anti-convulsion was addressed in the present study."7.73Involvement of taurine in penicillin-induced epilepsy and anti-convulsion of acupuncture: a preliminary report. ( Cheng, JS; Guo, JC; Jin, HB; Li, Q; Yang, R, 2005)
"The level of urinary taurine and 17-hydroxycorticosteroids were estimated in 19 cases of epilepsy."7.66Urinary excretion of taurine in epilepsy. ( Baliga, L; Raja, A; Rao, A; Rao, SN, 1983)
"Administration of taurine to a cat suffering from naturally occurring chronic (about 3 years) epilepsy caused disappearance of the clinical manifestation of the seizures as well as a marked improvement in the previously grossly abnormal EEG."7.65Taurine treatment of spontaneous chronic epilepsy in a cat. ( Jasper, HH; Koyama, I; van Gelder, NM, 1977)
"Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected."7.65Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975)
"Taurine was given orally (1."5.26[Orally-administered taurine in therapy-resistant epilepsy (author's transl)]. ( König, P; Kriechbaum, G; Presslich, O; Schubert, H; Schuster, P; Sieghart, W, 1977)
"Taurine was the only amino acid to be increased in epilepsy."5.25Free amino acids in serum of patients with epilepsy: significant increase in taurine. ( Delsedime, M; Durelli, L; Monaco, F; Mutani, R, 1975)
"An experimental model based on kainic acid (KA) injections replicates many phenomenological features of human temporal lobe epilepsy, the most common type of epilepsy in adults."3.75Prevention of epilepsy by taurine treatments in mice experimental model. ( Auladell, C; Camins, A; Duque, D; Junyent, F; Pallàs, M; Romero, R; Utrera, J, 2009)
"The potential role of taurine on epilepsy and acupuncture anti-convulsion was addressed in the present study."3.73Involvement of taurine in penicillin-induced epilepsy and anti-convulsion of acupuncture: a preliminary report. ( Cheng, JS; Guo, JC; Jin, HB; Li, Q; Yang, R, 2005)
"Parenteral injection of kainic acid (KA), a glutamate receptor agonist, causes severe and stereotyped behavioral convulsions in mice and is used as a rodent model for human temporal lobe epilepsy."3.72Prevention of epileptic seizures by taurine. ( El Idrissi, A; Messing, J; Scalia, J; Trenkner, E, 2003)
"Roles for melatonin, taurine, and the pineal gland in epilepsy are examined."3.67Could supplementary dietary tryptophan and taurine prevent epileptic seizures? ( Maurizi, CP, 1985)
"The level of urinary taurine and 17-hydroxycorticosteroids were estimated in 19 cases of epilepsy."3.66Urinary excretion of taurine in epilepsy. ( Baliga, L; Raja, A; Rao, A; Rao, SN, 1983)
" Three different situations associated with altered cortical conditions were studied: cortical hyperexcitability induced by cobalt epilepsy (mouse); chronic stimulation of the optic tectum by light adaptation (fish); and anatomic alteration of the optic tectum following unilateral enucleation (fish)."3.66Alterations in the compartmentalized metabolism of glutamic acid with changed cerebral conditions. ( Drujan, BD; van Gelder, NM, 1980)
"Administration of taurine to a cat suffering from naturally occurring chronic (about 3 years) epilepsy caused disappearance of the clinical manifestation of the seizures as well as a marked improvement in the previously grossly abnormal EEG."3.65Taurine treatment of spontaneous chronic epilepsy in a cat. ( Jasper, HH; Koyama, I; van Gelder, NM, 1977)
"Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected."3.65Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975)
"Taurine was administered orally to 25 intractable epileptic children, ranging in age from 4 months to 12 years."2.65Therapeutic trial by taurine for intractable childhood epilepsies. ( Fukuyama, Y; Ochiai, Y, 1982)
"Taurine is an organic osmolyte involved in cell volume regulation, and provides a substrate for the formation of bile salts."2.48Review: taurine: a "very essential" amino acid. ( Ripps, H; Shen, W, 2012)
" However, in selected cases, depending on the effectiveness of the interventions, dosage reductions or discontinuation of medications may be possible."2.44Natural approaches to epilepsy. ( Gaby, AR, 2007)
"Taurine has recently been added to infant formulas (about 50 mg/L)."2.37Taurine: its biological role and clinical implications. ( Chesney, RW, 1985)
"Vigabatrin is a highly effective antiseizure medication, but its use is limited due to concerns about retinal toxicity."1.43Plasma taurine levels are not affected by vigabatrin in pediatric patients. ( Mabud, TS; Porter, BE; Reimer, R; Spelbrink, EM, 2016)
"This taurine increase was highly reversible."1.28The epileptogenic action of the taurine analogue guanidinoethane sulfonate may be caused by a blockade of GABA receptors. ( Ambrosio, E; Herranz, AS; Herreras, O; Martin del Rio, R; Menéndez, N; Orensanz, LM; Solis, JM, 1990)
"In audiogenic seizure-susceptible (AGS) mice, evidence suggests a role for dopamine as well as GABA and possibly serotonin."1.27Neurotransmitter abnormalities in genetically epileptic rodents. ( Dailey, JW; Jobe, PC; Laird, HE, 1984)
"When kainic acid was included in the dialysis buffer, taurine was doubled in taurine-supplemented kittens, but it was only slightly affected in deficient animals."1.27Pentylenetetrazol seizure threshold and extracellular levels of cortical amino acids in taurine-deficient kittens. ( Lehmann, A, 1987)
"Taurine was given orally (1."1.26[Orally-administered taurine in therapy-resistant epilepsy (author's transl)]. ( König, P; Kriechbaum, G; Presslich, O; Schubert, H; Schuster, P; Sieghart, W, 1977)
"Taurine was the only amino acid to be increased in epilepsy."1.25Free amino acids in serum of patients with epilepsy: significant increase in taurine. ( Delsedime, M; Durelli, L; Monaco, F; Mutani, R, 1975)
"Thus taurine, which has an anticonvulsant action appears to partially correct the amino acid imbalance in epileptics."1.25Levels of free amino acids in serum and cerebrospinal fluid after administration of taurine to epileptic and normal subjects. ( Delsedime, M; Durelli, L; Monaco, F; Mutani, R, 1975)

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199064 (69.57)18.7374
1990's7 (7.61)18.2507
2000's14 (15.22)29.6817
2010's7 (7.61)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oja, SS3
Saransaari, P1
Chen, R1
Okabe, A1
Sun, H1
Sharopov, S1
Hanganu-Opatz, IL1
Kolbaev, SN1
Fukuda, A1
Luhmann, HJ1
Kilb, W1
Spelbrink, EM1
Mabud, TS1
Reimer, R1
Porter, BE1
Radwan, NM1
El Hay Ahmed, NA1
Ibrahim, KM1
Khedr, ME1
Aziz, MA1
Khadrawy, YA1
Junyent, F2
Utrera, J2
Romero, R2
Pallàs, M2
Camins, A2
Duque, D1
Auladell, C2
Maciejak, P1
Szyndler, J1
Turzyńska, D1
Sobolewska, A1
Taracha, E1
Skórzewska, A1
Lehner, M1
Bidziński, A1
Hamed, A1
Wisłowska-Stanek, A1
Płaźnik, A1
Porquet, D1
de Lemos, L1
Heim, MK1
Gidal, BE1
Filatova, YB1
Voronina, TA1
Klodt, PM1
Kudrin, VS2
Nerobkova, LN1
Rider, FK1
Avakyan, GN1
Ripps, H1
Shen, W1
El-Abhar, HS1
El Gawad, HM1
El Idrissi, A1
Messing, J1
Scalia, J1
Trenkner, E1
Kirchner, A1
Breustedt, J1
Rosche, B1
Heinemann, UF1
Schmieden, V1
GORDON, N1
WILSON, VK1
Li, Q2
Guo, JC2
Jin, HB3
Cheng, JS3
Yang, R3
Li, B1
Gu, J1
Baran, H1
Liu, J1
Wang, BE1
Gaby, AR1
Schmidt, D1
Laird, HE2
Dailey, JW2
Jobe, PC2
Craig, CR2
Kontro, P1
Alvarez, A1
Marcano de Cotte, D1
Pérez, JR1
Requena, MA1
Vallecalle, E1
Drujan, BD2
Durelli, L4
Mutani, R7
Gurevich, VS1
Goodman, HO4
Connolly, BM1
McLean, W1
Resnick, M1
Bonhaus, DW1
Lippincott, SE1
Huxtable, RJ2
Rao, A1
Baliga, L1
Raja, A1
Rao, SN1
van Gelder, NM13
Janjua, NA1
Metrakos, K1
MacGibbon, B1
Metrakos, JD1
Siatitsas, I1
Ménini, C1
Gloor, P1
Fukuyama, Y1
Ochiai, Y1
Bonhaus, D1
Lombardini, JB1
Frigyesi, TL1
Airaksinen, EM1
Marnela, KM1
Leino, E1
Pääkkönen, L1
Anyanwu, E1
Harding, GF1
Monaco, F3
Gianelli, M1
Schiavella, MP1
Naldi, P1
Cantello, R1
Torta, R1
Verzé, L1
Doretto, MC1
Burger, RL1
Mishra, PK1
Garcia-Cairasco, N1
Wilson, CL1
Maidment, NT1
Shomer, MH1
Behnke, EJ1
Ackerson, L1
Fried, I1
Engel, J1
Dammerman, RS1
Kriegstein, AR1
Raevskiĭ, KS1
Avakian, GN1
Nesterova, SI1
Gusev, EI1
Collins, GG1
Gaito, J1
Koyama, I3
Jasper, HH1
Svatý, J1
Mantovani, J1
DeVivo, DC1
Iwata, H1
Yamagami, S1
Lee, E1
Matsuda, T1
Baba, A1
Sherwin, AL2
Sacks, C1
Anderman, F1
König, P1
Kriechbaum, G1
Presslich, O1
Schubert, H1
Schuster, P1
Sieghart, W1
Sturman, JA1
Barbeau, A5
Inoue, N1
Tsukada, Y1
Butterworth, RF1
Delsedime, M5
Lehmann, A3
Herranz, AS1
Solis, JM1
Herreras, O1
Menéndez, N1
Ambrosio, E1
Orensanz, LM1
Martin del Rio, R1
Lloyd, KG1
Scatton, B1
Voltz, C1
Bryere, P1
Valin, A1
Naquet, R1
Kendler, BS1
Hartley, SG1
Shihabi, Z1
Fariello, RG2
Golden, GT2
McNeal, RB1
Allen, IC1
Grieve, A1
Griffiths, R1
Collins, BW1
Swanton, CH1
Remy, CN1
Hiramatsu, M1
Ogawa, K1
Kabuto, H1
Mori, A1
Ente, P1
Hagberg, H1
Lazarewicz, JW1
Jacobson, I1
Hamberger, A1
Yoshida, M1
Izumi, K1
Koja, T1
Fukuda, T1
Munekata, E1
Nakanishi, T1
Tanizawa, K1
Mizuno, T1
Ueda, K1
Maurizi, CP1
Chesney, RW1
Donaldson, J2
Bergamini, L2
Fariello, R2
Hartman, ER1
Rasmussen, T1
Courtois, A1
Ekelund, H1
Gamstorp, I1
Von Studnitz, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study in Adolescents With Bipolar Disorder[NCT00391001]Phase 14 participants (Actual)Interventional2006-02-28Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for taurine and Epilepsy

ArticleYear
Taurine and epilepsy.
    Epilepsy research, 2013, Volume: 104, Issue:3

    Topics: Amino Acids; Animals; Disease Models, Animal; Epilepsy; Humans; Neurotransmitter Agents; Taurine

2013
Vigabatrin-associated retinal damage: potential biochemical mechanisms.
    Acta neurologica Scandinavica, 2012, Volume: 126, Issue:4

    Topics: Animals; Anticonvulsants; Epilepsy; Humans; Retinal Diseases; Taurine; Vigabatrin

2012
Review: taurine: a "very essential" amino acid.
    Molecular vision, 2012, Volume: 18

    Topics: Amino Acids, Essential; Animals; Brain; Ciliary Body; Cornea; Cytoprotection; Diabetes Mellitus; Epi

2012
Natural approaches to epilepsy.
    Alternative medicine review : a journal of clinical therapeutic, 2007, Volume: 12, Issue:1

    Topics: Biotin; Carnitine; Diet; Dietary Supplements; Epilepsy; Fatty Acids, Essential; Folic Acid; Humans;

2007
The current status of taurine in epilepsy.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Epilepsy; Humans; Taurine

1983
[Taurine and the function of excitable tissues].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1984, Volume: 70, Issue:7

    Topics: Animals; Behavior, Animal; Biological Transport; Calcium; Cardiovascular Physiological Phenomena; Ca

1984
Glutamic acid in nervous tissue and changes of the taurine content: its implication in the treatment of epilepsy.
    Advances in biochemical psychopharmacology, 1981, Volume: 29

    Topics: Animals; Cerebral Cortex; Epilepsy; Glutamates; Humans; Nerve Tissue; Neuroglia; Neurons; Taurine

1981
The involvement of taurine in the action mechanism of sodium valproate (VPA) in the treatment of epilepsy.
    Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia, 1993, Volume: 43, Issue:1-2

    Topics: Brain; Epilepsy; Humans; Taurine; Valproic Acid

1993
Transient actions of neurotransmitters during neocortical development.
    Epilepsia, 2000, Volume: 41, Issue:8

    Topics: Animals; Calcium Channels; Cats; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, N

2000
Taurine - monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2001, Volume: 6, Issue:1

    Topics: Alcoholism; Alzheimer Disease; Animals; Cardiovascular Diseases; Cystic Fibrosis; Diabetes Mellitus;

2001
On the role of taurine in the mammalian central nervous system.
    Essays in neurochemistry and neuropharmacology, 1977, Volume: 1

    Topics: Animals; Brain; Central Nervous System; Epilepsy; Humans; Membranes; Neurotransmitter Agents; Spinal

1977
The kindling effect as a model of epilepsy.
    Psychological bulletin, 1976, Volume: 83, Issue:6

    Topics: Amygdala; Animals; Behavior, Animal; Brain; Electric Stimulation; Electrophysiology; Epilepsy; Model

1976
Taurine, the compartmentalized metabolism of glutamic acid, and the epilepsies.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:3

    Topics: Animals; Body Fluid Compartments; Epilepsy; Glutamates; Humans; Models, Biological; Taurine

1978
The brain, the heart and taurine.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1975, Volume: 2, Issue:4

    Topics: Analgesia; Brain; Epilepsy; Humans; Muscles; Muscular Diseases; Myocardium; Retina; Seizures; Taurin

1975
The neuropharmacology of taurine.
    Life sciences, 1975, Sep-01, Volume: 17, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Corpus Striatum; Epilepsy; Humans; Hypothalamus; Retina; Taurine

1975
Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy.
    Progress in clinical and biological research, 1990, Volume: 351

    Topics: Action Potentials; Animals; Brain; Epilepsy; Glutamates; Glutamic Acid; Humans; Migraine Disorders;

1990
Taurine: an overview of its role in preventive medicine.
    Preventive medicine, 1989, Volume: 18, Issue:1

    Topics: Animals; Cardiovascular Diseases; Cystic Fibrosis; Epilepsy; Humans; Infant, Newborn; Liver Diseases

1989
Taurine and related amino acids in seizure disorders--current controversies.
    Progress in clinical and biological research, 1985, Volume: 179

    Topics: Amino Acids; Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Epilepsy; g

1985
Taurine: its biological role and clinical implications.
    Advances in pediatrics, 1985, Volume: 32

    Topics: Animals; Bile Acids and Salts; Blood Platelets; Brain; Child; Epilepsy; Heart; Heart Failure; Humans

1985

Trials

3 trials available for taurine and Epilepsy

ArticleYear
Do taurine and its analogs or cogeners have actions in common?
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Amino Acids; Animals; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Female; Humans; Mice;

1981
Therapeutic trial by taurine for intractable childhood epilepsies.
    Brain & development, 1982, Volume: 4, Issue:1

    Topics: Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Electroencephalography; Epilepsy

1982
Taurine and related amino acids in seizure disorders--current controversies.
    Progress in clinical and biological research, 1985, Volume: 179

    Topics: Amino Acids; Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Epilepsy; g

1985

Other Studies

71 other studies available for taurine and Epilepsy

ArticleYear
Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus.
    The Journal of physiology, 2014, May-15, Volume: 592, Issue:10

    Topics: Animals; Animals, Newborn; Anticonvulsants; Cells, Cultured; Epilepsy; Glycine; Hippocampus; Rats; R

2014
Plasma taurine levels are not affected by vigabatrin in pediatric patients.
    Epilepsia, 2016, Volume: 57, Issue:8

    Topics: Age Factors; Analysis of Variance; Anticonvulsants; Child, Preschool; Cohort Studies; Epilepsy; Fema

2016
Effect of infrared laser irradiation on amino acid neurotransmitters in an epileptic animal model induced by pilocarpine.
    Photomedicine and laser surgery, 2009, Volume: 27, Issue:3

    Topics: Alanine Transaminase; Amino Acids; Analysis of Variance; Animals; Aspartate Aminotransferases; Aspar

2009
Prevention of epilepsy by taurine treatments in mice experimental model.
    Journal of neuroscience research, 2009, May-01, Volume: 87, Issue:6

    Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Calpain; Cell Death; Chromatography, High Pre

2009
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
    Brain research, 2009, Jul-28, Volume: 1282

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Re

2009
Decrease of calbindin-d28k, calretinin, and parvalbumin by taurine treatment does not induce a major susceptibility to kainic acid.
    Journal of neuroscience research, 2011, Volume: 89, Issue:7

    Topics: Animals; Calbindin 1; Calbindin 2; Calbindins; Calcium-Binding Proteins; Disease Models, Animal; Dis

2011
Changes in the levels of inhibitory and excitatory amino acids in the brain structures of female rats with cobalt epileptogenic focus during different phases of the estrous cycle.
    Bulletin of experimental biology and medicine, 2011, Volume: 152, Issue:1

    Topics: Animals; Animals, Outbred Strains; Aspartic Acid; Cobalt; Epilepsy; Estrous Cycle; Excitatory Amino

2011
Modulation of cortical nitric oxide synthase, glutamate, and redox state by nifedipine and taurine in PTZ-kindled mice.
    Epilepsia, 2003, Volume: 44, Issue:3

    Topics: Animals; Anticonvulsants; Antioxidants; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dose-Res

2003
Prevention of epileptic seizures by taurine.
    Advances in experimental medicine and biology, 2003, Volume: 526

    Topics: Animals; Chloride Channel Agonists; Chloride Channels; Epilepsy; Kainic Acid; Male; Receptors, GABA-

2003
Effects of taurine and glycine on epileptiform activity induced by removal of Mg2+ in combined rat entorhinal cortex-hippocampal slices.
    Epilepsia, 2003, Volume: 44, Issue:9

    Topics: Action Potentials; Animals; Entorhinal Cortex; Epilepsy; Female; Glycine; Hippocampus; In Vitro Tech

2003
ABNORMAL AMINO-ACID EXCRETION IN CEREBRAL DISEASE.
    Developmental medicine and child neurology, 1963, Volume: 5

    Topics: Brain Diseases; Cerebrospinal Fluid; Child; Chromatography; Cystine; Epilepsy; Glutamates; Humans; I

1963
Involvement of taurine in penicillin-induced epilepsy and anti-convulsion of acupuncture: a preliminary report.
    Acupuncture & electro-therapeutics research, 2005, Volume: 30, Issue:1-2

    Topics: Acupuncture Therapy; Animals; Behavior, Animal; Combined Modality Therapy; Dose-Response Relationshi

2005
Electro-acupuncture improves epileptic seizures induced by kainic acid in taurine-depletion rats.
    Acupuncture & electro-therapeutics research, 2005, Volume: 30, Issue:3-4

    Topics: Animals; Brain; Electroacupuncture; Epilepsy; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Taurine

2005
Alterations of taurine in the brain of chronic kainic acid epilepsy model.
    Amino acids, 2006, Volume: 31, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Epilepsy; Kainic Acid; Rats; Rats, Sprague

2006
Taurine participates in the anticonvulsive effect of electroacupuncture.
    Advances in experimental medicine and biology, 2006, Volume: 583

    Topics: Animals; Anticonvulsants; Electroacupuncture; Epilepsy; Excitatory Amino Acid Agonists; Kainic Acid;

2006
[Neurotransmitters and epilepsy. The antiepileptic effect of biogenic amines gamma-aminobutyric-acid and taurine in patients with epilepsy (author's transl)].
    Der Nervenarzt, 1980, Volume: 51, Issue:10

    Topics: Anticonvulsants; Dopamine; Epilepsy; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Serot

1980
Does taurine have clinical significance?
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Animals; Behavior; Calcium; Circadian Rhythm; Epilepsy; gamma-Aminobutyric Acid; Homeostasis; Humans

1981
Neurotransmitter abnormalities in genetically epileptic rodents.
    Federation proceedings, 1984, Volume: 43, Issue:10

    Topics: Acoustic Stimulation; Animals; Epilepsy; gamma-Aminobutyric Acid; Mice; Mice, Mutant Strains; Neurot

1984
Evidence for a role of neurotransmitters in the mechanism of topical convulsant models.
    Federation proceedings, 1984, Volume: 43, Issue:10

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Aspartic Acid; Brain; Choline O-Acetyltransferase; Dis

1984
Free amino acids in epilepsy: possible role of taurine.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 93

    Topics: Amino Acids; Animals; Brain; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilep

1983
Taurine- and penicillin-induced epileptic activity.
    Journal of neuroscience research, 1984, Volume: 11, Issue:2

    Topics: Animals; Electroencephalography; Epilepsy; Evoked Potentials; Male; Motor Cortex; Neural Inhibition;

1984
Taurine transport in epilepsy.
    Clinical chemistry, 1980, Volume: 26, Issue:3

    Topics: Child; Down Syndrome; Epilepsy; Female; Humans; Kinetics; Male; Reference Values; Taurine

1980
Subcellular distribution of neuroactive amino acids in brains of genetically epileptic rats.
    Epilepsia, 1984, Volume: 25, Issue:5

    Topics: Alanine; Amino Acids; Animals; Brain Chemistry; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Gluta

1984
Urinary excretion of taurine in epilepsy.
    Acta neurologica Scandinavica, 1983, Volume: 68, Issue:6

    Topics: Adolescent; Adult; Epilepsy; Female; Humans; Male; Middle Aged; Taurine

1983
Plasma amino acids in 3/sec spike-wave epilepsy.
    Neurochemical research, 1980, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; G

1980
Feline generalized penicillin epilepsy: changes of glutamic acid and taurine parallel the progressive increase in excitability of the cortex.
    Epilepsia, 1983, Volume: 24, Issue:2

    Topics: Animals; Brain; Cats; Cerebral Cortex; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Gl

1983
Decreased taurine transport in epileptic rats.
    Proceedings of the Western Pharmacology Society, 1982, Volume: 25

    Topics: Animals; Blood Platelets; Brain; Epilepsy; In Vitro Techniques; Rats; Rats, Inbred Strains; Synaptos

1982
Taurine-induced thalamocortical dissociative effects in an experimental model of epilepsy.
    Progress in clinical and biological research, 1981, Volume: 68

    Topics: Action Potentials; Animals; Brain; Cats; Cerebellum; Cerebral Cortex; Disease Models, Animal; Epilep

1981
Effects of taurine treatment on epileptic patients.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Adolescent; Adult; Aged; Amino Acids; Child; Double-Blind Method; Epilepsy; Female; Humans; Male; Mi

1980
Alterations in the compartmentalized metabolism of glutamic acid with changed cerebral conditions.
    Brain research, 1980, Nov-03, Volume: 200, Issue:2

    Topics: Animals; Brain; Cerebral Cortex; Cobalt; Epilepsy; Fishes; Glutamates; Glutamine; Mice; Neuroglia; N

1980
Plasma amino acid alterations in idiopathic generalized epilepsy: an investigation in probands and their first-degree relatives.
    Italian journal of neurological sciences, 1994, Volume: 15, Issue:3

    Topics: Adult; Amino Acids; Aspartic Acid; Epilepsy; Family; Female; Glutamates; Glycine; Humans; Male; Taur

1994
A microdialysis study of amino acid concentrations in the extracellular fluid of the substantia nigra of freely behaving GEPR-9s: relationship to seizure predisposition.
    Epilepsy research, 1994, Volume: 17, Issue:2

    Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Epilepsy; Extracellular Space; Male; Mic

1994
Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy.
    Epilepsy research, 1996, Volume: 26, Issue:1

    Topics: Amino Acids; Animals; Electroencephalography; Epilepsy; Excitatory Amino Acids; gamma-Aminobutyric A

1996
[Features of neurotransmitter pool in cerebrospinal fluid of patients with epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:6

    Topics: Adult; Aspartic Acid; Brain; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Huma

2001
Taurine treatment of spontaneous chronic epilepsy in a cat.
    Epilepsia, 1977, Volume: 18, Issue:1

    Topics: Administration, Oral; Animals; Brain; Cat Diseases; Cats; Drug Administration Schedule; Electroencep

1977
[Taurine and epilepsy].
    Ceskoslovenska pediatrie, 1979, Volume: 34, Issue:2

    Topics: Central Nervous System; Deficiency Diseases; Epilepsy; Humans; Taurine; Zinc

1979
Effects of taurine on seizures and growth hormone release in epileptic patients.
    Archives of neurology, 1979, Volume: 36, Issue:11

    Topics: Adolescent; Adult; Child; Epilepsy; Growth Hormone; Homovanillic Acid; Humans; Taurine

1979
Increase of brain taurine contents of E1 mice by physiological stimulation.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:4

    Topics: Animals; Anticonvulsants; Brain Chemistry; Brain Stem; Cerebellum; Cerebral Cortex; Epilepsy; Mice;

1979
Biochemical observations following administration of taurine to patients with epilepsy.
    Brain research, 1975, Aug-29, Volume: 94, Issue:2

    Topics: Adolescent; Adult; Alanine; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool

1975
[Orally-administered taurine in therapy-resistant epilepsy (author's transl)].
    Wiener klinische Wochenschrift, 1977, Feb-10, Volume: 89, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Child; Epilepsy; Female; Humans; Male; Taurine

1977
Taurine in nutrition.
    Comprehensive therapy, 1977, Volume: 3, Issue:10

    Topics: Animals; Blindness; Brain; Cysteine; Epilepsy; Female; Humans; Infant; Infant Nutritional Physiologi

1977
Free amino acids in serum of patients with epilepsy: significant increase in taurine.
    Epilepsia, 1975, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Blood-Brain Barrier; Chromatography, Ion Exchange; Epilepsy; Female;

1975
Levels of free amino acids in serum and cerebrospinal fluid after administration of taurine to epileptic and normal subjects.
    Epilepsia, 1975, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Amino Acids; Epilepsy; Female; Glutamates; Humans; Male; Taurine

1975
Relation between release of taurine and phosphoethanolamine and osmoregulation in experimental epilepsy.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: Amino Acids; Amygdala; Animals; Brain; Dialysis; Epilepsy; Ethanolamines; Hippocampus; Homeostasis;

1992
The epileptogenic action of the taurine analogue guanidinoethane sulfonate may be caused by a blockade of GABA receptors.
    Journal of neuroscience research, 1990, Volume: 26, Issue:1

    Topics: Animals; Convulsants; Epilepsy; gamma-Aminobutyric Acid; Rats; Rats, Inbred Strains; Receptors, GABA

1990
Cerebrospinal fluid amino acid and monoamine metabolite levels of Papio papio: correlation with photosensitivity.
    Brain research, 1986, Jan-22, Volume: 363, Issue:2

    Topics: Amino Acids; Animals; Biogenic Amines; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid;

1986
Urinary excretion of taurine in epilepsy.
    Neurochemical research, 1989, Volume: 14, Issue:2

    Topics: Autoanalysis; Biomarkers; Creatinine; Epilepsy; Humans; Reference Values; Taurine

1989
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
    Journal of neurochemistry, 1986, Volume: 46, Issue:5

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric A

1986
The hyperexcited brain: glutamic acid release and failure of inhibition.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Action Potentials; Animals; Brain; Cats; Epilepsy; Epilepsy, Post-Traumatic; Evoked Potentials; Fish

1986
Plasma and urinary taurine in epilepsy.
    Clinical chemistry, 1988, Volume: 34, Issue:4

    Topics: Anticonvulsants; Electroencephalography; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; T

1988
Pentylenetetrazol seizure threshold and extracellular levels of cortical amino acids in taurine-deficient kittens.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:3

    Topics: Amino Acids; Animals; Cats; Cerebral Cortex; Epilepsy; Extracellular Space; Female; Kainic Acid; Mal

1987
Reduced uptake and release of 5-hydroxytryptamine and taurine in the cerebral cortex of epileptic El mice.
    Epilepsy research, 1987, Volume: 1, Issue:1

    Topics: Animals; Cerebral Cortex; Epilepsy; In Vitro Techniques; Mice; Mice, Neurologic Mutants; Potassium;

1987
The epileptogenic action of 6-aminomethyl-3-methyl,1-4H-1,2,6-benzothiadiazine-1,1-diazide hydrochloride (TAG): non-specific versus specific antitaurine pathogenesis.
    Brain research, 1986, Aug-13, Volume: 380, Issue:1

    Topics: Action Potentials; Animals; Benzothiadiazines; Cerebral Cortex; Electroencephalography; Epilepsy; ga

1986
Alterations in extracellular amino acids and Ca2+ following excitotoxin administration and during status epilepticus.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amino Acids; Animals; Aspartic Acid; Bicuculline; Calcium; Epilepsy; Ethanolamines; Extracellular Sp

1986
Inhibitory effect of taurine on wet-dog shakes produced by [D-Ala2,Met5] enkephalinamide with reference to effects on hippocampal epileptic discharges.
    Neuropharmacology, 1986, Volume: 25, Issue:12

    Topics: Animals; Behavior, Animal; Electroencephalography; Enkephalin, Methionine; Epilepsy; Hippocampus; Ma

1986
Taurine treatment for spontaneous epilepsy in the cat.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1986, Volume: 48, Issue:5

    Topics: Animals; Cat Diseases; Cats; Epilepsy; Female; Taurine

1986
Taurine transport in sibs of epileptics.
    American journal of medical genetics, 1986, Volume: 25, Issue:4

    Topics: Biological Transport; Epilepsy; Humans; Pedigree; Taurine

1986
Could supplementary dietary tryptophan and taurine prevent epileptic seizures?
    Medical hypotheses, 1985, Volume: 18, Issue:4

    Topics: Diet; Epilepsy; gamma-Aminobutyric Acid; Humans; Melatonin; Monoamine Oxidase; Pineal Gland; Taurine

1985
Taurine in epilepsy.
    Lancet (London, England), 1973, Aug-18, Volume: 2, Issue:7825

    Topics: Epilepsy; Humans; Taurine

1973
Glutamate dehydrogenase, glutamic acid decarboxylase, and GABA amino transferase in epileptic mouse cortex.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:5

    Topics: Animals; Carboxy-Lyases; Cerebral Cortex; Cobalt; Epilepsy; gamma-Aminobutyric Acid; Glutamate Dehyd

1974
First clinical experience on the antiepileptic action of taurine.
    European neurology, 1974, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Child; Drug Evaluation; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic;

1974
Zinc, taurine, and epilepsy.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adenosine Triphosphatases; Adult; Aminobutyrates; Animals; Behavior, Animal; Brain; Cerebral Cortex;

1974
Effects of taurine on cortical acute epileptic foci.
    Brain research, 1974, Apr-12, Volume: 70, Issue:1

    Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Cobalt; Disease Models, Animal; Electroencephalogra

1974
Concentration of amino acids in the brain of cobalt-epileptic rat.
    Epilepsia, 1973, Volume: 14, Issue:4

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Cobalt; Disease Mode

1973
Amino acid content of epileptogenic human brain: focal versus surrounding regions.
    Brain research, 1972, May-26, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Cerebral Cortex; Chil

1972
Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy.
    Brain research, 1972, Aug-25, Volume: 43, Issue:2

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electro

1972
Antagonism by taurine of cobalt induced epilepsy in cat and mouse.
    Brain research, 1972, Nov-27, Volume: 47, Issue:1

    Topics: Amino Acids; Aminobutyrates; Animals; Cats; Cerebral Cortex; Cobalt; Electroencephalography; Epileps

1972
Zinc, taurine, and epilepsy.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Animals; Anticonvulsants; Copper; Epilepsy; Hippocampus; Humans; Hypothalamus; Rats; Taurine; Zinc

1973
[Antiepileptic effect of taurine administered by intra-carotid way in the cat].
    Rivista di neurologia, 1974, Volume: 44, Issue:2

    Topics: Animals; Anticonvulsants; Carotid Arteries; Cats; Epilepsy; Injections, Intra-Arterial; Taurine

1974
Amino acids in the cobalt-induced epileptogenic and nonepileptogenic cat's cortex.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:8

    Topics: Amino Acids; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electroencephalography; Epilepsy

1972
Apparent response of impaired mental development, minor motor epilepsy and ataxia to pyridoxine.
    Acta paediatrica Scandinavica, 1969, Volume: 58, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Ataxia; Child; Child, Preschool; Electroencephalography; Epile

1969