flurazepam has been researched along with Epilepsy in 4 studies
Flurazepam: A benzodiazepine derivative used mainly as a hypnotic.
flurazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Excerpt | Relevance | Reference |
---|---|---|
"A form of endogenous (binaural) inhibition in inferior colliculus neurons, which is proposed to be GABA-mediated, was also significantly reduced in the epilepsy-prone rat as compared with the normal rat." | 1.27 | Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat. ( Caspary, DM; Faingold, CL; Gehlbach, G, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Deutsch, SI | 1 |
Mastropaolo, J | 1 |
Burket, JA | 1 |
Rosse, RB | 1 |
Dodson, AM | 1 |
Miller, JW | 1 |
Ferrendelli, JA | 1 |
Faingold, CL | 1 |
Gehlbach, G | 1 |
Caspary, DM | 1 |
4 other studies available for flurazepam and Epilepsy
Article | Year |
---|---|
An epigenetic intervention interacts with genetic strain differences to modulate the stress-induced reduction of flurazepam's antiseizure efficacy in the mouse.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Butyrates; Disease Models, Animal; Dizocilpine Malea | 2009 |
Nursing care study - drug overdose: dealing with an unknown quantity.
Topics: Adult; Epilepsy; Female; Flurazepam; Humans; Nursing Care; Phenobarbital | 1982 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobut | 1990 |
Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat.
Topics: Animals; Bicuculline; Epilepsy; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Inferior Coll | 1986 |