2-deoxy-2-fluorogalactose profile

2-deoxy-2-fluorogalactose: structure given in first source; used as a tracer for evaluation of liver function by PET [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	162629
SCHEMBL ID	458017
MeSH ID	M0141283

Synonym
fdgal
2-deoxy-2-fluoro-galactose
51146-53-3
(2r,3s,4s,5r)-2-fluoro-3,4,5,6-tetrahydroxyhexanal
AKOS006272984
2-deoxy-2-(18f)fluoro-d-galactose
d-galactose, 2-deoxy-2-fluoro-
n5w0cej232 ,
2-deoxy-2-fluorogalactose
unii-n5w0cej232
SCHEMBL458017
238418-53-6
W-203627
2-deoxy-2-fluoro-d-galactose - non-animal origin

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	8 (25.81)	18.7374
1990's	8 (25.81)	18.2507
2000's	4 (12.90)	29.6817
2010's	11 (35.48)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (3.23%)	5.53%
Reviews	2 (6.45%)	6.00%
Case Studies	2 (6.45%)	4.05%
Observational	0 (0.00%)	0.25%
Other	26 (83.87%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
hydrogen Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.	1.97	1	0	elemental hydrogen; elemental molecule; gas molecular entity	antioxidant; electron donor; food packaging gas; fuel; human metabolite
thymidine [no description available]	1.98	1	0	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; metabolite; mouse metabolite
floxuridine Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.. floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.	1.98	1	0	nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; radiosensitizing agent
9,10-dimethyl-1,2-benzanthracene 9,10-Dimethyl-1,2-benzanthracene: Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.. 7,12-dimethyltetraphene : A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke.	1.97	1	0	ortho-fused polycyclic arene; tetraphenes	carcinogenic agent
uridine [no description available]	1.98	1	0	uridines	drug metabolite; fundamental metabolite; human metabolite
galactose galactopyranose : The pyranose form of galactose.	4.7	11	0	D-galactose; galactopyranose	Escherichia coli metabolite; mouse metabolite
uridine triphosphate Uridine Triphosphate: Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.	1.97	1	0	pyrimidine ribonucleoside 5'-triphosphate; uridine 5'-phosphate	Escherichia coli metabolite; mouse metabolite
methionine Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.	3.48	2	0	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
3-o-methylglucose 3-O-Methylglucose: A non-metabolizable glucose analogue that is not phosphorylated by hexokinase. 3-O-Methylglucose is used as a marker to assess glucose transport by evaluating its uptake within various cells and organ systems. (J Neurochem 1993;60(4):1498-504). 3-O-methyl-D-glucose : A D-aldohexose that is D-glucose in which the hydrogen of the hydroxy group at position 3 has been substituted by a methyl group. It is a non-metabolisable glucose analogue that is not phosphorylated by hexokinase and is used as a marker to assess glucose transport by evaluating its uptake within various cells and organ systems.	2.06	1	0	D-aldohexose derivative
fucose Fucose: A six-member ring deoxysugar with the chemical formula C6H12O5. It lacks a hydroxyl group on the carbon at position 6 of the molecule.. L-fucopyranose : The pyranose form of L-fucose.. fucose : Any deoxygalactose that is deoxygenated at the 6-position.	9.15	31	1	fucopyranose; L-fucose	Escherichia coli metabolite; mouse metabolite
mannose mannopyranose : The pyranose form of mannose.	1.97	1	0	D-aldohexose; D-mannose; mannopyranose	metabolite
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	2.68	3	0	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
galactose aldohexose : A hexose with a (potential) aldehyde group at one end.	2.06	1	0
1-deoxynojirimycin 1-deoxy-nojirimycin: structure in first source. duvoglustat : An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration.	2.05	1	0	2-(hydroxymethyl)piperidine-3,4,5-triol; piperidine alkaloid	anti-HIV agent; anti-obesity agent; bacterial metabolite; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; plant metabolite
castanospermine castanospermine: indolizidine alkaloid from seeds of Australian legume, Castanospermum australe. castanospermine : A tetrahydroxyindolizidine alkaloid that consists of octahydroindolizine having four hydroxy substituents located at positions 1, 6, 7 and 8 (the 1S,6S,7R,8R,8aR-diastereomer).	2.05	1	0	indolizidine alkaloid	anti-HIV-1 agent; anti-inflammatory agent; EC 3.2.1.* (glycosidase) inhibitor; metabolite
methionine methyl ester [no description available]	1.98	1	0
methylthymidine methylthymidine: RN given refers to N-3-methylthymidine	1.98	1	0
fluorodeoxyglucose f18 Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)	4.33	6	0	2-deoxy-2-((18)F)fluoro-D-glucose; 2-deoxy-2-fluoro-aldehydo-D-glucose
deoxyglucose Deoxyglucose: 2-Deoxy-D-arabino-hexose. An antimetabolite of glucose with antiviral activity.. deoxyglucose : A deoxyhexose comprising glucose having at least one hydroxy group replaced by hydrogen.	4.17	5	0
6-deoxy-6-fluorogalactose 6-deoxy-6-fluorogalactose: RN given refers to (D)-isomer	1.98	1	0
migalastat migalastat: a potent inhibitor of glycolipid biosynthesis	2.05	1	0	piperidines
brefeldin a [no description available]	2.05	1	0	macrolide antibiotic	Penicillium metabolite

Condition	Relationship Strength	Studies	Trials
Cancer of Liver [description not available]	4.66	6	1
Colorectal Cancer [description not available]	3.53	1	1
Liver Neoplasms Tumors or cancer of the LIVER.	4.66	6	1
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	3.53	1	1
Diabetic Feet [description not available]	3.09	1	0
Diabetic Foot Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.	3.09	1	0
Cirrhosis, Liver [description not available]	2.49	2	0
Alcoholic Cirrhosis [description not available]	2.1	1	0
Liver Dysfunction [description not available]	2.1	1	0
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.	2.49	2	0
Liver Cirrhosis, Alcoholic FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.	2.1	1	0
Liver Diseases Pathological processes of the LIVER.	2.1	1	0
Hepatocellular Carcinoma [description not available]	2.93	4	0
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	2.93	4	0
Carcinoma, Epidermoid [description not available]	2.93	1	0
Cancer of Head [description not available]	2.93	1	0
Hypopharyngeal Cancer [description not available]	2.93	1	0
Cancer of Larynx [description not available]	2.93	1	0
Cancer of Mouth [description not available]	2.93	1	0
Cancer of Oropharnyx [description not available]	2.93	1	0
Local Neoplasm Recurrence [description not available]	2.93	1	0
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	2.93	1	0
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)	2.93	1	0
Hypopharyngeal Neoplasms Tumors or cancer of the HYPOPHARYNX.	2.93	1	0
Laryngeal Neoplasms Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.	2.93	1	0
Mouth Neoplasms Tumors or cancer of the MOUTH.	2.93	1	0
Oropharyngeal Neoplasms Tumors or cancer of the OROPHARYNX.	2.93	1	0
Aura [description not available]	2.03	1	0
Angiomatosis Oculoorbital-Thalamic Syndrome [description not available]	2.03	1	0
Angiomatosis A condition with multiple tumor-like lesions caused either by congenital or developmental malformations of BLOOD VESSELS, or reactive vascular proliferations, such as in bacillary angiomatosis. Angiomatosis is considered non-neoplastic.	2.03	1	0
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)	2.03	1	0
Sturge-Weber Syndrome A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.	2.03	1	0
Spinal Neoplasms New abnormal growth of tissue in the SPINE.	1.98	1	0
Experimental Hepatoma [description not available]	2.38	2	0
Adrenocortical Carcinoma A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.	2	1	0
Adrenal Cortex Cancer [description not available]	2	1	0
Adrenal Cortex Neoplasms Tumors or cancers of the ADRENAL CORTEX.	2	1	0
Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.	2	1	0
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	1.98	1	0
Cancer of Lung [description not available]	1.98	1	0
Metastase [description not available]	1.98	1	0
Experimental Neoplasms [description not available]	2.38	2	0
Lung Neoplasms Tumors or cancer of the LUNG.	1.98	1	0
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	1.98	1	0
Experimental Mammary Neoplasms [description not available]	2.38	2	0
Reticulum Cell-Like Sarcoma, Yoshida [description not available]	1.97	1	0
Benign Neoplasms [description not available]	2.88	1	0
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.88	1	0

2-deoxy-2-fluorogalactose

Description

Cross-References

Synonyms (14)

Research

Studies (31)

Market Indicators

Research Demand Index: 11.15

Study Types