Page last updated: 2024-10-25

citalopram and Epilepsy

citalopram has been researched along with Epilepsy in 9 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
" In this paper we describe two patients with comorbid epilepsy, major depression, and panic disorder, whose serum citalopram levels increased and antidepressant response changed when concurrent carbamazepine treatment was substituted with oxcarbazepine."3.69Substituting carbamazepine with oxcarbazepine increases citalopram levels. A report on two cases. ( Koponen, H; Leinonen, E; Lepola, U, 1996)
"Both pseudoseizures and hysterical stridor are associated commonly with sexual abuse, eating disorders, depression, substance abuse, anxiety disorders, and personality disorders."1.32Pseudoseizures and hysterical stridor. ( Kaufman, KR; Mohebati, A; Sotolongo, A, 2004)
" El mouse convulsions were inhibited by chronic administration of citalopram (80 mg/kg/day, p."1.29Chronic administration of citalopram inhibited El mouse convulsions and decreased monoamine oxidase-A activity. ( Endo, A; Kabuto, H; Kurimoto, T; Mori, A; Takei, M; Yokoi, I, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chu, CS1
Lee, FL1
Bai, YM1
Su, TP1
Tsai, SJ1
Chen, TJ1
Hsu, JW1
Chen, MH1
Liang, CS1
Pardo-Peña, K1
Medina-Ceja, L1
Morales-Villagrán, A1
Wanders, AJ1
de Leeuw, AS1
van Megen, HJ1
Choi, HC1
Kim, YI1
Song, HK1
Kim, JE1
Kim, DS1
Kang, TC1
Kaufman, KR1
Mohebati, A1
Sotolongo, A1
Sterr, A1
Padberg, F1
Amann, B1
Mergl, R1
Mulert, C1
Juckel, G1
Hegerl, U1
Pogarell, O1
Albano, C1
Cupello, A1
Mainardi, P1
Scarrone, S1
Favale, E1
Kabuto, H1
Yokoi, I1
Endo, A1
Takei, M1
Kurimoto, T1
Mori, A1
Leinonen, E1
Lepola, U1
Koponen, H1

Other Studies

9 other studies available for citalopram and Epilepsy

ArticleYear
Antidepressant drugs use and epilepsy risk: A nationwide nested case-control study.
    Epilepsy & behavior : E&B, 2023, Volume: 140

    Topics: Antidepressive Agents; Case-Control Studies; Citalopram; Epilepsy; Humans; Selective Serotonin Reupt

2023
Serotonin modulates fast ripple activity in rats with spontaneous recurrent seizures.
    Brain research, 2014, Oct-02, Volume: 1583

    Topics: Animals; Catheters, Indwelling; Citalopram; Disease Models, Animal; Electrodes, Implanted; Electroen

2014
[Diagnosis of epilepsy complicated by panic disorder and a non-specific reaction to a SSRI].
    Tijdschrift voor psychiatrie, 2010, Volume: 52, Issue:5

    Topics: Adult; Citalopram; Diagnosis, Differential; Epilepsy; Humans; Male; Panic Disorder; Selective Seroto

2010
Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats.
    Brain research, 2010, Oct-21, Volume: 1357

    Topics: Analysis of Variance; Animals; Citalopram; Electroencephalography; Epilepsy; Fluoxetine; gamma-Amino

2010
Pseudoseizures and hysterical stridor.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2

    Topics: Academic Medical Centers; Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Second

2004
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroence

2006
Successful treatment of epilepsy with serotonin reuptake inhibitors: proposed mechanism.
    Neurochemical research, 2006, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Citalopram; Clinical Trials as Topic; Epilepsy; Female; Fluoxe

2006
Chronic administration of citalopram inhibited El mouse convulsions and decreased monoamine oxidase-A activity.
    Acta medica Okayama, 1994, Volume: 48, Issue:6

    Topics: Administration, Oral; Animals; Anticonvulsants; Brain; Citalopram; Disease Models, Animal; Epilepsy;

1994
Substituting carbamazepine with oxcarbazepine increases citalopram levels. A report on two cases.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Carbamazepine; Citalopram; Depressive Disorder; Drug

1996