Page last updated: 2024-10-25

clomipramine and Epilepsy

clomipramine has been researched along with Epilepsy in 7 studies

Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"could increase the risk of seizures."1.26[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents]. ( Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J, 1976)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernik, MA1
Corregiari, FM1
Braun, IM1
Flechter, S1
Rabey, JM1
Regev, I1
Borenstein, N1
Vardi, J1
Hess, CW1
Hertrich, O1
Fischer, W1
Rabending, G1
Heydenreich, F1
Herzer, H1
Altenstein, R1
Grimmberger, E1
Fernández-Jaén, A1
Martínez-Bermejo, A1
López-Martín, V1
Pascual-Castroviejo, I1
Escande, M1
Gayral, L1
Golberger, E1
Jarrige, A1
Kulik, J1

Other Studies

7 other studies available for clomipramine and Epilepsy

ArticleYear
Panic attacks in the differential diagnosis and treatment of resistant epilepsy.
    Depression and anxiety, 2002, Volume: 15, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Clonazepam; Diagnosis, Diffe

2002
Convulsive attacks due to antidepressant drug overdoses: case reports and discussion.
    General hospital psychiatry, 1983, Volume: 5, Issue:3

    Topics: Adult; Antidepressive Agents; Cerebral Cortex; Clomipramine; Dibenzazepines; Electroencephalography;

1983
[Narcolepsy--epilepsy. Differential diagnosis].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1984, Jun-12, Volume: 73, Issue:24

    Topics: Amnesia; Cataplexy; Clomipramine; Diagnosis, Differential; Electroencephalography; Epilepsy; Halluci

1984
[Ataractic treatment in psychiatry and general medicine. Overview of preparations, 3].
    Fortschritte der Medizin, 1983, Jun-09, Volume: 101, Issue:22

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Chlorprothixene; Clobaza

1983
[Use possibilities of quantitative electroencephalography in psychiatry and psychopharmacology].
    Sammlung zwangloser Abhandlungen aus dem Gebiete der Psychiatrie und Neurologie, 1982, Volume: 50

    Topics: Cerebral Cortex; Clomipramine; Delayed-Action Preparations; Double-Blind Method; Electroencephalogra

1982
[Munchausen syndrome by proxy: report of one case with epilepsy].
    Revista de neurologia, 1998, Volume: 26, Issue:153

    Topics: Antidepressive Agents, Tricyclic; Child; Child Abuse; Clomipramine; Epilepsy; Humans; Male; Maternal

1998
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
    L'Encephale, 1976, Volume: 2, Issue:2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography;

1976