diazoxide has been researched along with Epilepsy in 11 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since 1969 leucine sensitive hypoglycemia has been diagnosed in 4 infants." | 7.65 | [Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)]. ( Lücking, T, 1976) |
| " In this study, we investigated DZ attenuating neuronal loss caused by pilocarpine-induced seizures in rat hippocampus." | 3.77 | Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat. ( Cao, L; Chi, Z; Jiang, H; Xie, N; Xue, Y; Zhao, X, 2011) |
| "Since 1969 leucine sensitive hypoglycemia has been diagnosed in 4 infants." | 3.65 | [Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)]. ( Lücking, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| De Los Santos-La Torre, MA | 2 |
| Del Águila-Villar, CM | 2 |
| Lu-de Lama, LR | 2 |
| Nuñez-Almache, O | 2 |
| Chávez-Tejada, EM | 2 |
| Espinoza-Robles, OA | 2 |
| Pinto-Ibárcena, PM | 2 |
| Calagua-Quispe, MR | 2 |
| Azabache-Tafur, PM | 2 |
| Tucto-Manchego, RM | 2 |
| Ağladıoğlu, SY | 1 |
| Savaş Erdeve, S | 1 |
| Cetinkaya, S | 1 |
| Baş, VN | 1 |
| Peltek Kendirci, HN | 1 |
| Onder, A | 1 |
| Aycan, Z | 1 |
| Xue, Y | 1 |
| Xie, N | 1 |
| Cao, L | 1 |
| Zhao, X | 1 |
| Jiang, H | 1 |
| Chi, Z | 1 |
| Semiz, S | 1 |
| Bircan, I | 1 |
| Akçurin, S | 1 |
| Mihçi, E | 1 |
| Melikoglu, M | 1 |
| Karagüzel, G | 1 |
| Kiliçaslan, B | 1 |
| Karpuzoğlu, G | 1 |
| Mattia, D | 1 |
| Nagao, T | 1 |
| Rogawski, MA | 1 |
| Avoli, M | 1 |
| Lawson, K | 1 |
| Menni, F | 1 |
| de Lonlay, P | 1 |
| Sevin, C | 1 |
| Touati, G | 1 |
| Peigné, C | 1 |
| Barbier, V | 1 |
| Nihoul-Fékété, C | 1 |
| Saudubray, JM | 1 |
| Robert, JJ | 1 |
| Fujinawa, A | 1 |
| Kawai, I | 1 |
| Ohashi, H | 1 |
| Kimura, S | 1 |
| Petro, DJ | 1 |
| Vannucci, RC | 1 |
| Kulin, HE | 1 |
| Lücking, T | 1 |
| Wolff, F | 1 |
| Hirsch, E | 1 |
| Wales, J | 1 |
| Viktora, J | 1 |
1 review available for diazoxide and Epilepsy
| Article | Year |
|---|---|
Is there a role for potassium channel openers in neuronal ion channel disorders?
Topics: Aminopyridines; Animals; Anticonvulsants; Antihypertensive Agents; Ataxia; Carbamates; Diazoxide; Ep | 2000 |
10 other studies available for diazoxide and Epilepsy
| Article | Year |
|---|---|
Hyperinsulinism-hyperammonemia syndrome in two Peruvian children with refractory epilepsy.
Topics: Child; Congenital Hyperinsulinism; Diazoxide; Drug Resistant Epilepsy; Epilepsy; Glutamate Dehydroge | 2023 |
Hyperinsulinism-hyperammonemia syndrome in two Peruvian children with refractory epilepsy.
Topics: Child; Congenital Hyperinsulinism; Diazoxide; Drug Resistant Epilepsy; Epilepsy; Glutamate Dehydroge | 2023 |
Hyperinsulinism-hyperammonemia syndrome in two Peruvian children with refractory epilepsy.
Topics: Child; Congenital Hyperinsulinism; Diazoxide; Drug Resistant Epilepsy; Epilepsy; Glutamate Dehydroge | 2023 |
Hyperinsulinism-hyperammonemia syndrome in two Peruvian children with refractory epilepsy.
Topics: Child; Congenital Hyperinsulinism; Diazoxide; Drug Resistant Epilepsy; Epilepsy; Glutamate Dehydroge | 2023 |
Hyperinsulinemic hypoglycemia: experience in a series of 17 cases.
Topics: Child; Child, Preschool; Developmental Disabilities; Diazoxide; Epilepsy; Female; Humans; Hyperinsul | 2013 |
Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat.
Topics: Androstadienes; Animals; Decanoic Acids; Diazoxide; Epilepsy; Hydroxy Acids; Male; Malondialdehyde; | 2011 |
Persistent hyperinsulinaemic hypoglycaemia of infancy: case report.
Topics: Anti-Inflammatory Agents; Blood Glucose; Consanguinity; Diazoxide; Epilepsy; Glucagon; Humans; Hyper | 2002 |
Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice.
Topics: 4-Aminopyridine; Animals; Benzopyrans; Cromakalim; Diazoxide; Epilepsy; Hippocampus; Hypoxia, Brain; | 1994 |
Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia.
Topics: Age of Onset; Child; Child, Preschool; Developmental Disabilities; Diazoxide; Epilepsy; Humans; Hype | 2001 |
A case of musicogenic epilepsy.
Topics: Aged; Diazoxide; Electroencephalography; Epilepsy; Female; Humans; Music; Phenytoin | 1977 |
Letter: Diazoxide-diphenylhydantoin interaction.
Topics: Child, Preschool; Diazoxide; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Hypogly | 1976 |
[Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)].
Topics: Blood Glucose; Diazoxide; Dietary Proteins; Drug Hypersensitivity; Epilepsy; Female; Humans; Hypertr | 1976 |
Experimental and clinical studies with diazoxide.
Topics: Agammaglobulinemia; Animals; Blood Glucose; Diazoxide; Dogs; Edema; Epilepsy; Epinephrine; Female; H | 1968 |